183 results match your criteria Adiposis Dolorosa


Intravenous Lidocaine for Acute Pain: A Systematic Review.

Pharmacotherapy 2018 Dec 9;38(12):1250-1259. Epub 2018 Nov 9.

Loyola University Medical Center, Maywood, Illinois.

This systematic review evaluates the safety and efficacy of intravenous (IV) lidocaine for the treatment of acute pain in adult patients. The PubMed database was searched for randomized controlled trials, retrospective cohort studies, case series, and case reports evaluating the use of IV lidocaine for the treatment of acute pain in adult patients, published between January 1970 and January 2018. The primary outcome was pain reduction via the Visual Analog Scale, Verbal Rating Scale, or Numeric Rating Scale among patients treated with IV lidocaine and placebo or active controls. Read More

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http://dx.doi.org/10.1002/phar.2189DOI Listing
December 2018
19 Reads

Subcutaneous adipose tissue therapy reduces fat by dual X-ray absorptiometry scan and improves tissue structure by ultrasound in women with lipoedema and Dercum disease.

Clin Obes 2018 Dec 24;8(6):398-406. Epub 2018 Sep 24.

TREAT Program, College of Medicine, University of Arizona, Tucson, Arizona, USA.

Lipoedema is painful nodular subcutaneous adipose tissue (SAT) on legs and arms of women sparing the trunk. People with Dercum disease (DD) have painful SAT masses. Lipoedema and DD fat resists loss by diet and exercise. Read More

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http://dx.doi.org/10.1111/cob.12281DOI Listing
December 2018

Trauma-induced adiposis dolorosa (Dercum's disease).

BMJ Case Rep 2018 Mar 28;2018. Epub 2018 Mar 28.

Internal Medicine, Reading Hospital and Medical Center, West Reading, Pennsylvania, USA.

We present a case of a 39-year-old man who presented with chronic bilateral upper extremity pain associated with innumerable angiomyolipomas that developed 5 years after a motor vehicle accident involving his upper extremities. Our case notes the rare nature of painful adipose tissue deposits and the diagnostic challenges. Read More

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http://dx.doi.org/10.1136/bcr-2017-223869DOI Listing
March 2018
15 Reads

Cutaneous manifestations of obesity and themetabolic syndrome.

Clin Dermatol 2018 Jan - Feb;36(1):81-88. Epub 2017 Sep 8.

Department of Dermatology, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.

The cutaneous manifestations of obesity and the associated metabolic syndrome (MetS) may present with a wide variety of cutaneous findings, including acanthosis nigricans, acrochordon, cellulitis, psoriasis, hidradenitis suppurativa, acne, and hirsutism. Being aware of such clinical signs and the underlying systemic disorders may facilitate earlier diagnoses, thereby permitting earlier of therapy initiation and prevention of long-term sequelae. In this process, dermatologists are key figures in the early detection of MetS and its clinical manifestations. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2017.09.014DOI Listing
August 2018
17 Reads

Cutaneous lipomatosis: diagnosing a rare condition.

G Ital Dermatol Venereol 2017 12;152(6):678-680

Department of Dermatology and Venereology, Sapienza University, Umberto I Polyclinic, Rome, Italy.

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http://dx.doi.org/10.23736/S0392-0488.16.05410-9DOI Listing
December 2017
1 Read

Widespread painful nodules in a patient with rheumatoid arthritis.

Eur J Intern Med 2017 Dec 3;46:e1-e2. Epub 2017 May 3.

Clinica Medica, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1016/j.ejim.2017.04.022DOI Listing
December 2017
17 Reads

Differentiating lipedema and Dercum's disease.

Int J Obes (Lond) 2017 02 18;41(2):240-245. Epub 2016 Nov 18.

Department of Medicine, Medical Imaging and Pharmacy, University of Arizona, Tucson, AZ, USA.

Background: People with lipedema or Dercum's disease (DD) can have a similar distribution of excess painful nodular subcutaneous adipose tissue (SAT), making them difficult to differentiate.

Methods: Case series of 94 patients with DD, 160 with lipedema and 18 with both diagnoses (Lip+DD) from a single clinic in an academic medical center to improve identification and differentiation of these disorders by comparison of clinical findings, prevalence of type 2 diabetes (DM2), hypermobility by the Beighton score and assessment of a marker of inflammation, Total complement activity (CH50).

Results: Differences between groups were by Student's t-test with α of 0. Read More

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http://dx.doi.org/10.1038/ijo.2016.205DOI Listing
February 2017
9 Reads

Lipedema: A Relatively Common Disease with Extremely Common Misconceptions.

Plast Reconstr Surg Glob Open 2016 Sep 28;4(9):e1043. Epub 2016 Sep 28.

Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, Mo.; and Department of Medicine, University of Arizona, Banner University Medical Center, Tucson, Ariz.

Lipedema, or adiposis dolorosa, is a common adipose tissue disorder that is believed to affect nearly 11% of adult women worldwide. It is characterized most commonly by disproportionate adipocyte hypertrophy of the lower extremities, significant tenderness to palpation, and a failure to respond to extreme weight loss modalities. Women with lipedema report a rapid growth of the lipedema subcutaneous adipose tissue in the setting of stress, surgery, and/or hormonal changes. Read More

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http://dx.doi.org/10.1097/GOX.0000000000001043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055019PMC
September 2016
88 Reads

VISUAL VIGNETTE.

Endocr Pract 2016 08 26;22(8):1027. Epub 2016 Feb 26.

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http://dx.doi.org/10.4158/EP161236.VVDOI Listing
August 2016
11 Reads

Juxta-articular adiposis dolorosa (Dercum's disease type IV): report of four cases and treatment by dermolipectomy.

Wien Med Wochenschr 2015 Sep 20;165(17-18):374-7. Epub 2015 Aug 20.

Department of Anesthesiology and Intensive Medical Care, Emergency Medicine and Pain Management, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.

Juxta-articular adiposis dolorosa is a rare subtype of Dercum's disease. It manifests mainly on the medial parts of the knees. Pain and impaired mobility are common symptoms. Read More

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http://dx.doi.org/10.1007/s10354-015-0378-1DOI Listing
September 2015
12 Reads

Successful Treatment of Dercum's Disease by Transcutaneous Electrical Stimulation: A Case Report.

Medicine (Baltimore) 2015 Jun;94(24):e950

From the Diabetes Research Institute (SM, MS, EB); Department of Radiology, San Raffaele Hospital and Scientific Institute (CL); and San Raffaele Vita Salute University, Milan, Italy (AC, EB).

Dercum's disease is a rare condition of painful subcutaneous growth of adipose tissue. Etiology is unknown and pain is difficult to control. We report the case of a 57-year-old man with generalized diffuse Dercum's disease, who improved after the treatment with transcutaneous frequency rhythmic electrical modulation system (FREMS). Read More

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http://pdfs.journals.lww.com/md-journal/2015/06030/Successfu
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http://dx.doi.org/10.1097/MD.0000000000000950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616524PMC
June 2015
127 Reads

Imaging findings of adiposis dolorosa vs. massive localized lymphedema.

Skeletal Radiol 2015 Jun 13;44(6):839-47. Epub 2015 Feb 13.

Department of Radiology, H066, Milton S. Hershey Medical Center, 500 University Drive, P.O. Box 850, Hershey, PA, 17033, USA,

Purpose: Adiposis dolorosa (Dercum's disease) is a condition of benign, painful subcutaneous lipomatous lesions associated with weakness, endocrine and lipid abnormalities, and mental disturbances. There is little information documenting the cross-sectional imaging findings that differentiate it from lipomatous and neoplastic soft tissue masses, or massive localized lymphedema. The purpose of this study was to provide a radiological case series of adiposis dolorosa. Read More

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http://dx.doi.org/10.1007/s00256-015-2114-8DOI Listing
June 2015
8 Reads

Adiposis dolorosa.

Dermatol Online J 2014 Dec 16;20(12). Epub 2014 Dec 16.

New York University School of Medicine.

We report a 46-year-old woman with a nine-year history of obesity; chronic diffuse pain in the adipose tissue of her medial upper arms, lower trunk, and thighs; multiple biopsy-proven lipomas and angiolipomas; and a lipomatous pseudomass of the breast. Her systemic symptoms included generalized weakness, fatigue, memory impairment, and arthralgias. Although some of the lesions were tender, most were only appreciated with palpation. Read More

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December 2014
31 Reads

Francis Xavier Dercum: a man for all seasons.

Ann Clin Transl Neurol 2014 Mar 10;1(3):233-7. Epub 2014 Feb 10.

Rutgers New Jersey Medical School Newark, New Jersey ; Department of Surgery, Rutgers New Jersey Medical School Newark, New Jersey.

Francis Xavier Dercum (1856-1931) is known primarily for his prominence in the field of neurology and for his identification of "Adiposis Dolorosa", known as Dercum's disease. His brilliance, however, extends well beyond neurology. Born and raised in Philadelphia to parents of American and European descent, Dercum's natural curiosity oriented his interests toward medicine and philosophy. Read More

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http://dx.doi.org/10.1002/acn3.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184553PMC
March 2014
7 Reads

An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease.

Obesity (Silver Spring) 2014 Oct 9;22(10):2186-92. Epub 2014 Jul 9.

The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

Objective: Investigational, near-infrared fluorescence (NIRF) lymphatic imaging was used to assess lymphatic architecture and contractile function in participants diagnosed with Dercum's disease, a rare, poorly understood disorder characterized by painful lipomas in subcutaneous adipose tissues.

Methods: After informed consent and as part of an FDA-approved feasibility study to evaluate lymphatics in diseases in which their contribution has been implicated, three women diagnosed with Dercum's disease and four control subjects were imaged. Each participant received multiple intradermal and subcutaneous injections of indocyanine green (ICG, total dose ≤400 µg) in arms, legs, and/or trunk. Read More

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http://dx.doi.org/10.1002/oby.20836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180796PMC
October 2014
22 Reads
4 Citations
3.734 Impact Factor

Adiposis dolorosa (Dercum's disease): MRI and ultrasound appearances.

Clin Radiol 2013 Oct 25;68(10):1047-53. Epub 2013 Jun 25.

Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital, NHS Trust, Oswestry, UK.

Aim: To describe ultrasound and magnetic resonance imaging (MRI) features of adiposis dolorosa, Dercum's disease, and to evaluate the MRI features prospectively against a large number of MRI examinations.

Materials And Methods: Institutional review board approval for this study was obtained. The imaging features at MRI and ultrasound of 13 cases of adiposis dolorosa (nine female, four male; age range 32-72 years) were reviewed. Read More

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http://dx.doi.org/10.1016/j.crad.2013.05.004DOI Listing
October 2013
9 Reads

An uncommon association between lipomatous hypertrophy of the interatrial septum (LHIS) and Dercum's disease.

Eur J Dermatol 2013 May-Jun;23(3):406-7

Policlinico Umberto i Department of Dermatology Viale del policlinico 155 00100 Rome, Italy.

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http://dx.doi.org/10.1684/ejd.2013.2016DOI Listing
November 2015
13 Reads

A successful case of pain management using metformin in a patient with adiposis dolorosa.

Int J Clin Pharmacol Ther 2013 Jun;51(6):517-24

Department of Internal Medicine, Clinical Pharmacology, Medical University of Silesia, Katowice, Poland.

In this case report, we describe a patient with Dercum's disease who was successfully managed with metformin. The administration of metformin reduced pain intensity from 9/10 to 3/10 and favorably affected the profile of inflammatory cytokines (i.e. Read More

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http://dx.doi.org/10.5414/CP201878DOI Listing
June 2013
7 Reads

Evaluation of measurement of fat mass reduction after liposuction in obese patients.

J Plast Surg Hand Surg 2012 Dec 23;46(6):421-6. Epub 2012 Oct 23.

Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital , Malmö , Sweden.

Body composition measurements are used to evaluate surgical treatment, such as bariatric surgery in overweight patients. Nowadays, there are many different methods to measure body composition available. However, none of them has been validated for use in patients after operation. Read More

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http://dx.doi.org/10.3109/2000656X.2012.715086DOI Listing
December 2012
18 Reads

Quality-of-life in patients with Dercum's disease--before and after liposuction.

J Plast Surg Hand Surg 2012 Sep;46(3-4):252-6

Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.

Dercum's disease is characterised by obesity, pronounced pain in the adipose tissue, and a number of associated symptoms. Liposuction has been suggested as a treatment. However, the effect on quality-of-life after liposuction in Dercum's disease has never been investigated. Read More

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http://dx.doi.org/10.3109/2000656X.2012.698417DOI Listing
September 2012
26 Reads

Neuropeptide levels in Dercum's disease (adiposis dolorosa).

Reumatismo 2012 Jul 19;64(3):134-41. Epub 2012 Jul 19.

Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.

Dercum's disease (adiposis dolorosa) is characterised by adiposity and chronic pain in the adipose tissue. It has been proposed that conditions encompassing chronic pain have altered concentrations of neuropeptides involved in pain transmission. The aim of this investigation was to examine whether patients with Dercum's disease have abnormal concentrations of different neuropeptides. Read More

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http://dx.doi.org/10.4081/reumatismo.2012.134DOI Listing
July 2012
7 Reads

Depression in Dercum's disease and in obesity: a case control study.

BMC Psychiatry 2012 Jul 3;12:74. Epub 2012 Jul 3.

Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, SE-20502, Malmö, Sweden.

Background: Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms. The condition is usually accompanied by generalised weight gain. Many of the associated symptoms could also be signs of depression. Read More

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http://dx.doi.org/10.1186/1471-244X-12-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416699PMC
July 2012
20 Reads

How to diagnose a lipodystrophy syndrome.

Ann Endocrinol (Paris) 2012 Jun 28;73(3):170-89. Epub 2012 Jun 28.

Inserm U859, service d'endocrinologie et maladies métaboliques, hôpital Huriez, CHRU de Lille, 1, rue Polonovski, 59000 Lille, France.

The spectrum of adipose tissue diseases ranges from obesity to lipodystrophy, and is accompanied by insulin resistance syndrome, which promotes the occurrence of type 2 diabetes, dyslipidemia and cardiovascular complications. Lipodystrophy refers to a group of rare diseases characterized by the generalized or partial absence of adipose tissue, and occurs with or without hypertrophy of adipose tissue in other sites. They are classified as being familial or acquired, and generalized or partial. Read More

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http://linkinghub.elsevier.com/retrieve/pii/S000342661200093
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http://dx.doi.org/10.1016/j.ando.2012.04.010DOI Listing
June 2012
25 Reads

Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management.

Orphanet J Rare Dis 2012 Apr 30;7:23. Epub 2012 Apr 30.

Department of Clinical Sciences in Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.

Unlabelled: DEFINITION AND CLINICAL PICTURE: We propose the minimal definition of Dercum's disease to be generalised overweight or obesity in combination with painful adipose tissue. The associated symptoms in Dercum's disease include fatty deposits, easy bruisability, sleep disturbances, impaired memory, depression, difficulty concentrating, anxiety, rapid heartbeat, shortness of breath, diabetes, bloating, constipation, fatigue, weakness and joint aches.

Classification: We suggest that Dercum's disease is classified into: I. Read More

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http://dx.doi.org/10.1186/1750-1172-7-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444313PMC
April 2012
38 Reads

Lipoma - a case study.

Authors:
Emily Phillips

J Vis Commun Med 2011 Jun;34(2):68-9

Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK.

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http://dx.doi.org/10.3109/17453054.2011.579896DOI Listing
June 2011
6 Reads

[Picture of the month: dercum disease].

Ugeskr Laeger 2011 Jun;173(26):1887

Klinik for Plastikkirurgi og Brandsårsbehandling, Afsnit 2102, HovedOrtoCentret, Rigshospitalet, 2100 København Ø, Denmark.

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June 2011
5 Reads

Thermal and vibratory thresholds after liposuction in patients with Dercum's disease.

J Plast Surg Hand Surg 2011 Apr;45(2):72-6

Department of Clinical Sciences in Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.

Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms and is, in most patients, accompanied by obesity. Postoperative sensory change after liposuction is a well-known side effect, and probably caused by mechanical trauma to the nerves. The aim of this investigation was to find out whether the thermal and sensory sensation changed after liposuction in patients with Dercum's disease. Read More

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http://dx.doi.org/10.3109/2000656X.2011.561102DOI Listing
April 2011
14 Reads

Liposuction may reduce pain in Dercum's disease (adiposis dolorosa).

Pain Med 2011 Jun 11;12(6):942-52. Epub 2011 Apr 11.

Department of Clinical Sciences, Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.

Objective: The aim of this prospective study is to assess the effect of liposuction on the pain experienced by women with Dercum's disease (adiposis dolorosa).

Design: Pain was examined preoperatively and at 3 months, and 1, 2, 3, and 5 years after liposuction. The subjective pain sensation was evaluated with a visual analog scale and number of words chosen, and the objective pain sensation with the mechanical pressure pain threshold. Read More

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http://dx.doi.org/10.1111/j.1526-4637.2011.01101.xDOI Listing
June 2011
46 Reads

Dercum's disease as a cause of weight loss failure after gastric bypass surgery.

Surg Obes Relat Dis 2011 Mar-Apr;7(2):243-5. Epub 2010 Sep 17.

Department of Surgery, Chelsea and Westminster Hospital, Imperial College of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.soard.2010.09.007DOI Listing
August 2011
4 Reads

Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa.

J Pain Res 2010 Aug 20;3:147-53. Epub 2010 Aug 20.

Department of Medicine, University of California, San Diego, California, USA;

Adiposis dolorosa (AD) is a rare disorder of painful nodular subcutaneous fat accompanied by fatigue, difficulty with weight loss, inflammation, increased fluid in adipose tissue (lipedema and lymphedema), and hyperalgesia. Sequential compression relieves lymphedema pain; we therefore hypothesized that whole body cyclic pneumatic hypobaric compression may relieve pain in AD. To avoid exacerbating hyperalgesia, we utilized a touch-free method, which is delivered via a high-performance altitude simulator, the Cyclic Variations in Altitude Conditioning™ (CVAC™) process. Read More

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http://dx.doi.org/10.2147/JPR.S12351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004643PMC
August 2010
5 Reads

[Fatter through lipids or water. Lipohyperplasia dolorosa versus lymphedema].

Authors:
M E Cornely

Hautarzt 2010 Oct;61(10):873-9

Lipohyperplasia dolorosa and lymphedema are completely different disease entities, which are both, however, classified under lymphology. While in lipohyperplasia dolorosa a congenital lipid distribution disorder leads to a high volume insufficiency and the corresponding clinical symptoms, lymphedema is characterized by a congenital transport incompetence of the vessels or acquired disorders of transport capacity. Both lymphedemas of different genesis are familial volume alterations of the affected regions and the increase in volume is irreversible if not exclusively still in stage I or II. Read More

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http://dx.doi.org/10.1007/s00105-010-1987-7DOI Listing
October 2010
9 Reads

Adiposis dolorosa of scalp presenting with severe headache: an unusual case.

J Headache Pain 2010 Dec 2;11(6):539-41. Epub 2010 Sep 2.

Department of Medicine, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Parel, Mumbai, India.

A 46-year-old female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parieto-occipital areas and vertex 1 year back. Six weeks prior to the presentation to our service, she developed severe occipital headache refractory to drug treatment. She improved after bilateral greater occipital nerve blocks. Read More

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http://dx.doi.org/10.1007/s10194-010-0253-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476222PMC
December 2010
19 Reads

Dercum's disease: an unusual presentation.

Pain Med 2010 Sep 23;11(9):1430-4. Epub 2010 Jul 23.

Wellmont Hospital, Bristol, Tennessee, USA.

Dercum's disease, also known as adiposis dolorosa, is a rare disease characterized by the accumulation of painful subcutaneous deposits of mature adult fatty tissue around the thighs, trunk, and upper arms and usually in a multifocal distribution. We are reporting an unusual presentation of Dercum's disease, presenting as a single painful, erythematous lesion around the left hip in a 71-year old postmenopausal woman. This report emphasizes the unusual presentation of adiposa dolorosa with a new modality for therapy. Read More

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http://dx.doi.org/10.1111/j.1526-4637.2010.00828.xDOI Listing
September 2010
24 Reads

Microcannular tumescent liposuction in advanced lipedema and Dercum's disease.

G Ital Dermatol Venereol 2010 Apr;145(2):151-9

Department of Dermatology and Allergology, Academic Teaching Hospital of the Technical, University of Dresden, Dresden, Germany.

Aim: We evaluated the outcome and risks of tumescence liposuction in patients with advanced lipedema or Dercum's disease.

Methods: Six patients treated at a single center during the years 2004 to 2008 have been included. All patients were female and obese (body mass index 34 to 41. Read More

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April 2010
117 Reads

Puzzles in practice. Spinal epidural lipomatosis.

Authors:
Yehia Y Mishriki

Postgrad Med 2010 Jan;122(1):192-4

Penn State University College of Medicine, Allentown, PA 18103, USA.

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http://www.tandfonline.com/doi/full/10.3810/pgm.2010.01.2113
Publisher Site
http://dx.doi.org/10.3810/pgm.2010.01.2113DOI Listing
January 2010
10 Reads

Francis Xavier Dercum.

Authors:
Charles Sorbie

Orthopedics 2009 Dec;32(12):882

Queen's University.

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http://dx.doi.org/10.3928/01477447-20091020-03DOI Listing
December 2009
7 Reads

[Skin manifestations, treatment and rehabilitation in overweight and obesity].

Authors:
Eniko Wenczl

Orv Hetil 2009 Sep;150(37):1731-8

Fovárosi Onkormányzat Egyesített Szent István és Szent László Kórház és Rendelointézet Borgyógyászati és Lymphológiai Rehabilitációs Osztály Budapest Nagyvárad tér 1. 1095.

Overweight and obesity is a public health problem in Hungary and in the Western world. It is important to underline that obesity is an illness and an important risk factor for several skin and other diseases. An overview of skin diseases caused or aggravated by obesity (acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism, stria, adiposis dolorosa, lymphoedema, chronic venous insufficiency, plantar hyperkeratosis, lipoedema, skin infections, acne inversa, psoriasis, tophi) helps us to look and see as well. Read More

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http://dx.doi.org/10.1556/OH.2009.28693DOI Listing
September 2009
4 Reads

Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa.

Int J Obes (Lond) 2009 Sep 21;33(9):1031-8. Epub 2009 Jul 21.

Department of Medicine, University of California San Diego, San Diego, CA, USA.

Background: Adiposis dolorosa (AD) is a syndrome of obese and non-obese individuals whose hallmark is lipomatosis: unencapsulated painful fatty masses in subcutaneous fat. Lipomatosis may contain excess collagen and multi-nucleated giant (MNG) cells. Case reports suggest metabolic defects in AD. Read More

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http://dx.doi.org/10.1038/ijo.2009.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964847PMC
September 2009
7 Reads

A rare cause of mastalgia: Dercum's disease (adiposis dolorosa).

Tumori 2008 Sep-Oct;94(5):762-4

Breast Imaging Unit, Department of Radiology, European Institute of Oncology, Milan, Italy.

Among the symptoms reported by patients undergoing breast imaging, pain is one of the most common. Mastalgia is generally classified as cyclic, noncyclic, or extramammary. A rare cause of breast pain is Dercum's disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous lipomas. Read More

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January 2009
20 Reads

Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.

Rheumatol Int 2008 Nov 5;29(1):17-22. Epub 2008 Jul 5.

Kerckhoff-Clinic, Bad Nauheim, Germany,

Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Read More

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http://dx.doi.org/10.1007/s00296-008-0635-3DOI Listing
November 2008
31 Reads

Adiposis dolorosa as an etiology of abdominal pain.

Wien Klin Wochenschr 2008 ;120(7-8):251; author reply 251

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http://dx.doi.org/10.1007/s00508-008-0961-1DOI Listing
September 2008
10 Reads

Treatment of pain in Dercum's disease with Lidoderm (lidocaine 5% patch): a case report.

Pain Med 2008 Nov 11;9(8):1224-6. Epub 2008 Mar 11.

Department of Anesthesiology, Jefferson Pain Center, Jefferson Pain Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.

Introduction: Dercum's disease is a rare disorder characterized by multiple painful subcutaneous lipomas on the trunk and extremities. It most commonly occurs in obese, postmenopausal women. The pain associated with this condition is postulated to arise from enlarging lipomas producing pressure on peripheral nerves, thereby initiating pain and sometimes paresthesias. Read More

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http://dx.doi.org/10.1111/j.1526-4637.2008.00417.xDOI Listing
November 2008
16 Reads

Obesity and the skin: skin physiology and skin manifestations of obesity.

J Am Acad Dermatol 2007 Jun;56(6):901-16; quiz 917-20

Departments of Dermatology, Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

Unlabelled: Obesity is widely recognized as an epidemic in the Western world; however, the impact of obesity on the skin has received minimal attention. The purpose of this article is to highlight the association between obesity and dermatologic conditions. We review the impact of obesity on the skin, including skin physiology, skin manifestations of obesity, and dermatologic diseases aggravated by obesity. Read More

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http://linkinghub.elsevier.com/retrieve/pii/S019096220604105
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http://dx.doi.org/10.1016/j.jaad.2006.12.004DOI Listing
June 2007
44 Reads

Case records of the Massachusetts General Hospital. Case 25-2006. A 41-year-old woman with painful subcutaneous nodules.

N Engl J Med 2006 Aug;355(7):714-22

Department of Dermatology, Massachusetts General Hospital, Boston, USA.

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http://www.nejm.org/doi/10.1056/NEJMcpc069018
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http://dx.doi.org/10.1056/NEJMcpc069018DOI Listing
August 2006
11 Reads

[An uncommon cause of recurrent abdominal pain in a 63-year-old obese woman].

Dtsch Med Wochenschr 2006 Mar;131(9):434-7

Medizinische Klinik II, Krankenhaus Bad Oeynhausen.

History And Clinical Findings: A 63-year-old woman was admitted because of abdominal pain for 12 months, associated with an increasing abdominal distension. One month before a gastroscopy had revealed mild gastritis. The taking of proton pump inhibitors did not improve her symptoms. Read More

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http://dx.doi.org/10.1055/s-2006-932538DOI Listing
March 2006
6 Reads