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    176 results match your criteria Adiposis Dolorosa

    1 OF 4

    Trauma-induced adiposis dolorosa (Dercum's disease).
    BMJ Case Rep 2018 Mar 28;2018. Epub 2018 Mar 28.
    Internal Medicine, Reading Hospital and Medical Center, West Reading, Pennsylvania, USA.
    We present a case of a 39-year-old man who presented with chronic bilateral upper extremity pain associated with innumerable angiomyolipomas that developed 5 years after a motor vehicle accident involving his upper extremities. Our case notes the rare nature of painful adipose tissue deposits and the diagnostic challenges. Read More

    Differentiating lipedema and Dercum's disease.
    Int J Obes (Lond) 2017 02 18;41(2):240-245. Epub 2016 Nov 18.
    Department of Medicine, Medical Imaging and Pharmacy, University of Arizona, Tucson, AZ, USA.
    Background: People with lipedema or Dercum's disease (DD) can have a similar distribution of excess painful nodular subcutaneous adipose tissue (SAT), making them difficult to differentiate.

    Methods: Case series of 94 patients with DD, 160 with lipedema and 18 with both diagnoses (Lip+DD) from a single clinic in an academic medical center to improve identification and differentiation of these disorders by comparison of clinical findings, prevalence of type 2 diabetes (DM2), hypermobility by the Beighton score and assessment of a marker of inflammation, Total complement activity (CH50).

    Results: Differences between groups were by Student's t-test with α of 0. Read More

    Lipedema: A Relatively Common Disease with Extremely Common Misconceptions.
    Plast Reconstr Surg Glob Open 2016 Sep 28;4(9):e1043. Epub 2016 Sep 28.
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, Mo.; and Department of Medicine, University of Arizona, Banner University Medical Center, Tucson, Ariz.
    Lipedema, or adiposis dolorosa, is a common adipose tissue disorder that is believed to affect nearly 11% of adult women worldwide. It is characterized most commonly by disproportionate adipocyte hypertrophy of the lower extremities, significant tenderness to palpation, and a failure to respond to extreme weight loss modalities. Women with lipedema report a rapid growth of the lipedema subcutaneous adipose tissue in the setting of stress, surgery, and/or hormonal changes. Read More

    Juxta-articular adiposis dolorosa (Dercum's disease type IV): report of four cases and treatment by dermolipectomy.
    Wien Med Wochenschr 2015 Sep 20;165(17-18):374-7. Epub 2015 Aug 20.
    Department of Anesthesiology and Intensive Medical Care, Emergency Medicine and Pain Management, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
    Juxta-articular adiposis dolorosa is a rare subtype of Dercum's disease. It manifests mainly on the medial parts of the knees. Pain and impaired mobility are common symptoms. Read More

    Successful Treatment of Dercum's Disease by Transcutaneous Electrical Stimulation: A Case Report.
    Medicine (Baltimore) 2015 Jun;94(24):e950
    From the Diabetes Research Institute (SM, MS, EB); Department of Radiology, San Raffaele Hospital and Scientific Institute (CL); and San Raffaele Vita Salute University, Milan, Italy (AC, EB).
    Dercum's disease is a rare condition of painful subcutaneous growth of adipose tissue. Etiology is unknown and pain is difficult to control. We report the case of a 57-year-old man with generalized diffuse Dercum's disease, who improved after the treatment with transcutaneous frequency rhythmic electrical modulation system (FREMS). Read More

    Imaging findings of adiposis dolorosa vs. massive localized lymphedema.
    Skeletal Radiol 2015 Jun 13;44(6):839-47. Epub 2015 Feb 13.
    Department of Radiology, H066, Milton S. Hershey Medical Center, 500 University Drive, P.O. Box 850, Hershey, PA, 17033, USA,
    Purpose: Adiposis dolorosa (Dercum's disease) is a condition of benign, painful subcutaneous lipomatous lesions associated with weakness, endocrine and lipid abnormalities, and mental disturbances. There is little information documenting the cross-sectional imaging findings that differentiate it from lipomatous and neoplastic soft tissue masses, or massive localized lymphedema. The purpose of this study was to provide a radiological case series of adiposis dolorosa. Read More

    Adiposis dolorosa.
    Dermatol Online J 2014 Dec 16;20(12). Epub 2014 Dec 16.
    New York University School of Medicine.
    We report a 46-year-old woman with a nine-year history of obesity; chronic diffuse pain in the adipose tissue of her medial upper arms, lower trunk, and thighs; multiple biopsy-proven lipomas and angiolipomas; and a lipomatous pseudomass of the breast. Her systemic symptoms included generalized weakness, fatigue, memory impairment, and arthralgias. Although some of the lesions were tender, most were only appreciated with palpation. Read More

    Francis Xavier Dercum: a man for all seasons.
    Ann Clin Transl Neurol 2014 Mar 10;1(3):233-7. Epub 2014 Feb 10.
    Rutgers New Jersey Medical School Newark, New Jersey ; Department of Surgery, Rutgers New Jersey Medical School Newark, New Jersey.
    Francis Xavier Dercum (1856-1931) is known primarily for his prominence in the field of neurology and for his identification of "Adiposis Dolorosa", known as Dercum's disease. His brilliance, however, extends well beyond neurology. Born and raised in Philadelphia to parents of American and European descent, Dercum's natural curiosity oriented his interests toward medicine and philosophy. Read More

    An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease.
    Obesity (Silver Spring) 2014 Oct 9;22(10):2186-92. Epub 2014 Jul 9.
    The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
    Objective: Investigational, near-infrared fluorescence (NIRF) lymphatic imaging was used to assess lymphatic architecture and contractile function in participants diagnosed with Dercum's disease, a rare, poorly understood disorder characterized by painful lipomas in subcutaneous adipose tissues.

    Methods: After informed consent and as part of an FDA-approved feasibility study to evaluate lymphatics in diseases in which their contribution has been implicated, three women diagnosed with Dercum's disease and four control subjects were imaged. Each participant received multiple intradermal and subcutaneous injections of indocyanine green (ICG, total dose ≤400 µg) in arms, legs, and/or trunk. Read More

    Adiposis dolorosa (Dercum's disease): MRI and ultrasound appearances.
    Clin Radiol 2013 Oct 25;68(10):1047-53. Epub 2013 Jun 25.
    Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital, NHS Trust, Oswestry, UK.
    Aim: To describe ultrasound and magnetic resonance imaging (MRI) features of adiposis dolorosa, Dercum's disease, and to evaluate the MRI features prospectively against a large number of MRI examinations.

    Materials And Methods: Institutional review board approval for this study was obtained. The imaging features at MRI and ultrasound of 13 cases of adiposis dolorosa (nine female, four male; age range 32-72 years) were reviewed. Read More

    A successful case of pain management using metformin in a patient with adiposis dolorosa.
    Int J Clin Pharmacol Ther 2013 Jun;51(6):517-24
    Department of Internal Medicine, Clinical Pharmacology, Medical University of Silesia, Katowice, Poland.
    In this case report, we describe a patient with Dercum's disease who was successfully managed with metformin. The administration of metformin reduced pain intensity from 9/10 to 3/10 and favorably affected the profile of inflammatory cytokines (i.e. Read More

    Evaluation of measurement of fat mass reduction after liposuction in obese patients.
    J Plast Surg Hand Surg 2012 Dec 23;46(6):421-6. Epub 2012 Oct 23.
    Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital , Malmö , Sweden.
    Body composition measurements are used to evaluate surgical treatment, such as bariatric surgery in overweight patients. Nowadays, there are many different methods to measure body composition available. However, none of them has been validated for use in patients after operation. Read More

    Quality-of-life in patients with Dercum's disease--before and after liposuction.
    J Plast Surg Hand Surg 2012 Sep;46(3-4):252-6
    Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
    Dercum's disease is characterised by obesity, pronounced pain in the adipose tissue, and a number of associated symptoms. Liposuction has been suggested as a treatment. However, the effect on quality-of-life after liposuction in Dercum's disease has never been investigated. Read More

    Neuropeptide levels in Dercum's disease (adiposis dolorosa).
    Reumatismo 2012 Jul 19;64(3):134-41. Epub 2012 Jul 19.
    Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
    Dercum's disease (adiposis dolorosa) is characterised by adiposity and chronic pain in the adipose tissue. It has been proposed that conditions encompassing chronic pain have altered concentrations of neuropeptides involved in pain transmission. The aim of this investigation was to examine whether patients with Dercum's disease have abnormal concentrations of different neuropeptides. Read More

    Depression in Dercum's disease and in obesity: a case control study.
    BMC Psychiatry 2012 Jul 3;12:74. Epub 2012 Jul 3.
    Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, SE-20502, Malmö, Sweden.
    Background: Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms. The condition is usually accompanied by generalised weight gain. Many of the associated symptoms could also be signs of depression. Read More

    How to diagnose a lipodystrophy syndrome.
    Ann Endocrinol (Paris) 2012 Jun 28;73(3):170-89. Epub 2012 Jun 28.
    Inserm U859, service d'endocrinologie et maladies métaboliques, hôpital Huriez, CHRU de Lille, 1, rue Polonovski, 59000 Lille, France.
    The spectrum of adipose tissue diseases ranges from obesity to lipodystrophy, and is accompanied by insulin resistance syndrome, which promotes the occurrence of type 2 diabetes, dyslipidemia and cardiovascular complications. Lipodystrophy refers to a group of rare diseases characterized by the generalized or partial absence of adipose tissue, and occurs with or without hypertrophy of adipose tissue in other sites. They are classified as being familial or acquired, and generalized or partial. Read More

    Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management.
    Orphanet J Rare Dis 2012 Apr 30;7:23. Epub 2012 Apr 30.
    Department of Clinical Sciences in Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
    Unlabelled: DEFINITION AND CLINICAL PICTURE: We propose the minimal definition of Dercum's disease to be generalised overweight or obesity in combination with painful adipose tissue. The associated symptoms in Dercum's disease include fatty deposits, easy bruisability, sleep disturbances, impaired memory, depression, difficulty concentrating, anxiety, rapid heartbeat, shortness of breath, diabetes, bloating, constipation, fatigue, weakness and joint aches.

    Classification: We suggest that Dercum's disease is classified into: I. Read More

    Thermal and vibratory thresholds after liposuction in patients with Dercum's disease.
    J Plast Surg Hand Surg 2011 Apr;45(2):72-6
    Department of Clinical Sciences in Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
    Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms and is, in most patients, accompanied by obesity. Postoperative sensory change after liposuction is a well-known side effect, and probably caused by mechanical trauma to the nerves. The aim of this investigation was to find out whether the thermal and sensory sensation changed after liposuction in patients with Dercum's disease. Read More

    Liposuction may reduce pain in Dercum's disease (adiposis dolorosa).
    Pain Med 2011 Jun 11;12(6):942-52. Epub 2011 Apr 11.
    Department of Clinical Sciences, Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
    Objective: The aim of this prospective study is to assess the effect of liposuction on the pain experienced by women with Dercum's disease (adiposis dolorosa).

    Design: Pain was examined preoperatively and at 3 months, and 1, 2, 3, and 5 years after liposuction. The subjective pain sensation was evaluated with a visual analog scale and number of words chosen, and the objective pain sensation with the mechanical pressure pain threshold. Read More

    Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa.
    J Pain Res 2010 Aug 20;3:147-53. Epub 2010 Aug 20.
    Department of Medicine, University of California, San Diego, California, USA;
    Adiposis dolorosa (AD) is a rare disorder of painful nodular subcutaneous fat accompanied by fatigue, difficulty with weight loss, inflammation, increased fluid in adipose tissue (lipedema and lymphedema), and hyperalgesia. Sequential compression relieves lymphedema pain; we therefore hypothesized that whole body cyclic pneumatic hypobaric compression may relieve pain in AD. To avoid exacerbating hyperalgesia, we utilized a touch-free method, which is delivered via a high-performance altitude simulator, the Cyclic Variations in Altitude Conditioning™ (CVAC™) process. Read More

    [Fatter through lipids or water. Lipohyperplasia dolorosa versus lymphedema].
    Hautarzt 2010 Oct;61(10):873-9
    Lipohyperplasia dolorosa and lymphedema are completely different disease entities, which are both, however, classified under lymphology. While in lipohyperplasia dolorosa a congenital lipid distribution disorder leads to a high volume insufficiency and the corresponding clinical symptoms, lymphedema is characterized by a congenital transport incompetence of the vessels or acquired disorders of transport capacity. Both lymphedemas of different genesis are familial volume alterations of the affected regions and the increase in volume is irreversible if not exclusively still in stage I or II. Read More

    Adiposis dolorosa of scalp presenting with severe headache: an unusual case.
    J Headache Pain 2010 Dec 2;11(6):539-41. Epub 2010 Sep 2.
    Department of Medicine, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Parel, Mumbai, India.
    A 46-year-old female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parieto-occipital areas and vertex 1 year back. Six weeks prior to the presentation to our service, she developed severe occipital headache refractory to drug treatment. She improved after bilateral greater occipital nerve blocks. Read More

    Dercum's disease: an unusual presentation.
    Pain Med 2010 Sep 23;11(9):1430-4. Epub 2010 Jul 23.
    Wellmont Hospital, Bristol, Tennessee, USA.
    Dercum's disease, also known as adiposis dolorosa, is a rare disease characterized by the accumulation of painful subcutaneous deposits of mature adult fatty tissue around the thighs, trunk, and upper arms and usually in a multifocal distribution. We are reporting an unusual presentation of Dercum's disease, presenting as a single painful, erythematous lesion around the left hip in a 71-year old postmenopausal woman. This report emphasizes the unusual presentation of adiposa dolorosa with a new modality for therapy. Read More

    Microcannular tumescent liposuction in advanced lipedema and Dercum's disease.
    G Ital Dermatol Venereol 2010 Apr;145(2):151-9
    Department of Dermatology and Allergology, Academic Teaching Hospital of the Technical, University of Dresden, Dresden, Germany.
    Aim: We evaluated the outcome and risks of tumescence liposuction in patients with advanced lipedema or Dercum's disease.

    Methods: Six patients treated at a single center during the years 2004 to 2008 have been included. All patients were female and obese (body mass index 34 to 41. Read More

    [Skin manifestations, treatment and rehabilitation in overweight and obesity].
    Orv Hetil 2009 Sep;150(37):1731-8
    Fovárosi Onkormányzat Egyesített Szent István és Szent László Kórház és Rendelointézet Borgyógyászati és Lymphológiai Rehabilitációs Osztály Budapest Nagyvárad tér 1. 1095.
    Overweight and obesity is a public health problem in Hungary and in the Western world. It is important to underline that obesity is an illness and an important risk factor for several skin and other diseases. An overview of skin diseases caused or aggravated by obesity (acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism, stria, adiposis dolorosa, lymphoedema, chronic venous insufficiency, plantar hyperkeratosis, lipoedema, skin infections, acne inversa, psoriasis, tophi) helps us to look and see as well. Read More

    Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa.
    Int J Obes (Lond) 2009 Sep 21;33(9):1031-8. Epub 2009 Jul 21.
    Department of Medicine, University of California San Diego, San Diego, CA, USA.
    Background: Adiposis dolorosa (AD) is a syndrome of obese and non-obese individuals whose hallmark is lipomatosis: unencapsulated painful fatty masses in subcutaneous fat. Lipomatosis may contain excess collagen and multi-nucleated giant (MNG) cells. Case reports suggest metabolic defects in AD. Read More

    A rare cause of mastalgia: Dercum's disease (adiposis dolorosa).
    Tumori 2008 Sep-Oct;94(5):762-4
    Breast Imaging Unit, Department of Radiology, European Institute of Oncology, Milan, Italy.
    Among the symptoms reported by patients undergoing breast imaging, pain is one of the most common. Mastalgia is generally classified as cyclic, noncyclic, or extramammary. A rare cause of breast pain is Dercum's disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous lipomas. Read More

    Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
    Rheumatol Int 2008 Nov 5;29(1):17-22. Epub 2008 Jul 5.
    Kerckhoff-Clinic, Bad Nauheim, Germany,
    Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Read More

    Treatment of pain in Dercum's disease with Lidoderm (lidocaine 5% patch): a case report.
    Pain Med 2008 Nov 11;9(8):1224-6. Epub 2008 Mar 11.
    Department of Anesthesiology, Jefferson Pain Center, Jefferson Pain Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.
    Introduction: Dercum's disease is a rare disorder characterized by multiple painful subcutaneous lipomas on the trunk and extremities. It most commonly occurs in obese, postmenopausal women. The pain associated with this condition is postulated to arise from enlarging lipomas producing pressure on peripheral nerves, thereby initiating pain and sometimes paresthesias. Read More

    Obesity and the skin: skin physiology and skin manifestations of obesity.
    J Am Acad Dermatol 2007 Jun;56(6):901-16; quiz 917-20
    Departments of Dermatology, Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
    Unlabelled: Obesity is widely recognized as an epidemic in the Western world; however, the impact of obesity on the skin has received minimal attention. The purpose of this article is to highlight the association between obesity and dermatologic conditions. We review the impact of obesity on the skin, including skin physiology, skin manifestations of obesity, and dermatologic diseases aggravated by obesity. Read More

    [An uncommon cause of recurrent abdominal pain in a 63-year-old obese woman].
    Dtsch Med Wochenschr 2006 Mar;131(9):434-7
    Medizinische Klinik II, Krankenhaus Bad Oeynhausen.
    History And Clinical Findings: A 63-year-old woman was admitted because of abdominal pain for 12 months, associated with an increasing abdominal distension. One month before a gastroscopy had revealed mild gastritis. The taking of proton pump inhibitors did not improve her symptoms. Read More

    [Liposuction in children: clinical utility].
    Cir Pediatr 2005 Oct;18(4):188-91
    Hospital Niño Jesús, Madrid, España.
    Liposuction has become one of the most frequent aesthetic procedures. The "typical" patient is a young female with fat deposits in the trochanteric region. Gradually the safety of the technique together with the high satisfaction rate of the patients have contributed to the widening of its indications to other pathologies of the adipose tissue in different age populations. Read More

    [Dercum's disease: a case report].
    Ann Ital Med Int 2005 Jul-Sep;20(3):187-91
    Cattedra di Medicina Interna II, Dipartimento Internistico 2, Università degli Studi di Cagliari, Policlinico di Monserrato.
    A case of Dercum's disease in a 51-year-old obese woman with a history of brain vasculitis, and painful subcutaneous multiple lipomas is described. This disease, included in the category of rare diseases by the World Health Organization, first described in 1892 by Francis Xavier Dercum, is characterized by its prevalence among women, its familiarity, by the presence of multiple painful subcutaneous lipomas and its association with obesity, hypercholesterolemia and asthenia. The disease has to be differentiated from Madelung syndrome, the multiple familiar lipomatosis and Proteus' syndrome. Read More

    [Dercum's disease: a severe complication in a rare disease. A case report].
    Ann Chir Plast Esthet 2005 Jun 20;50(3):247-50. Epub 2005 Jan 20.
    Service de chirurgie plastique et maxillofaciale, centre hospitalier de Gonesse, 25, rue Pierre-de-Theilley, 95503 Gonesse, France.
    Dercum's disease or adiposis dolorasa is unusual and unknown. Four symptoms are typical. It is characterized by painful subcutaneous fatty tumors in postmenopausal woman. Read More

    Dercum's disease.
    Skinmed 2005 May-Jun;4(3):157-62; quiz 163-4
    Molecular and Population Genetics Laboratory, Cancer Research UK, London, England.
    Dercum's disease (adiposis dolorosa, lipomatosis dolorosa morbus Dercum), is a rare disorder resulting in painful fatty deposits around the upper legs, trunk, and upper arms. The portrait painted of Dercum's disease is very complicated, with many other disorders seen associated with the disease. There are no clear pathological mechanisms known, although it is suspected that there is either a metabolic or autoimmune component involved. Read More

    Dercum's disease (adiposis dolorosa): a new case-report.
    Joint Bone Spine 2004 Mar;71(2):147-9
    Rheumatology Department, Porte Madeleine Hospital, Orléans Regional Hospital Center, 10000 Orléans, France.
    Unlabelled: Dercum's disease, or adiposa dolorosa, is a rare condition characterized by the development of multiple painful subcutaneous lipomas. Postmenopausal women are selectively affected. The ankle area is an uncommon site of involvement. Read More

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