2,477 results match your criteria Adenomyosis Imaging


Malignant transformation of adenomyosis: literature review and meta-analysis.

Arch Gynecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Department of Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.

Purpose: To review and analyze risk factors and the pathology of malignant transformation of adenomyosis.

Methods: In this paper, the relevant research on current risks factors and the pathology of malignant transformation of adenomyosis was reviewed and analyzed by metaanalysis. All studies included were retrieved from the PUBMED. Read More

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December 2018

The Disease Phenotype of Adenomyosis-Affected Women Correlates With Specific Serum Cytokine Profiles.

Reprod Sci 2018 Dec 5:1933719118816852. Epub 2018 Dec 5.

1 Department of Gynaecology Obstetrics II and Reproductive Medicine, Faculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Paris Centre, Centre Hospitalier Universitaire (CHU) Cochin, Paris, France.

Background:: Adenomyosis (ADE) is an enigmatic uterine disorder. Several types have been previously described: diffuse adenomyosis (DIF-ADE), focal adenomyosis (FOC-ADE), and association of focal and diffuse lesions (FOC/DIF-ADE). Abnormal immune phenomena have been described that may provide an understanding of the pathophysiology of adenomyosis. Read More

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December 2018
2 Reads

Histological evaluation of the prevalence of adenomyosis, myomas and of their concomitance.

Minerva Ginecol 2018 Nov 27. Epub 2018 Nov 27.

Department of Medical Area, Institute of Obstetrics and Gynecology, University of Udine, Udine, Italy -

Background: The objective of this study is to evaluate the prevalence of adenomyosis, leiomyomas and of their concomitance in women who underwent hysterectomy.

Methods: An observational study carried out on a cohort of 347 women who underwent hysterectomy from a sample of 2383 patients who had gynecological surgery for benign disease in a single University Hospital between 2013 and 2016. An histological evaluation of all surgical specimens was carried out for the presence of adenomyosis and leiomyomas. Read More

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November 2018
1 Read

N 164 - Directive clinique de consensus pour la prise en charge de la douleur pelvienne chronique.

J Obstet Gynaecol Can 2018 Nov;40(11):e788-e836

Calgary, Alb.

Objectif: Améliorer La compréhension de la douleur pelvienne chronique (DPC) et fournir des directives cliniques factuelles qui bénéficieront aux fournisseurs de soins de santé primaires, aux obstétriciens-gynécologues et aux spécialistes de la douleur chronique.

Fardeau De La Souffrance: La DPC est une pathologie débilitante courante qui affecte les femmes. Elle est à l'origine d'importantes souffrances personnelles et de dépenses de santé considérables associées aux interventions, dont de multiples consultations et un grand nombre de traitements médicaux et chirurgicaux. Read More

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November 2018
1 Read

No. 164-Consensus Guidelines for the Management of Chronic Pelvic Pain.

J Obstet Gynaecol Can 2018 Nov;40(11):e747-e787

Calgary, AB.

Objective: To improve the understanding of chronic pelvic pain (CPP) and to provide evidence-based guidelines of value to primary care health professionals, general obstetricians and gynaecologists, and those who specialize in chronic pain.

Burden Of Suffering: CPP is a common, debilitating condition affecting women. It accounts for substantial personal suffering and health care expenditure for interventions, including multiple consultations and medical and surgical therapies. Read More

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November 2018
3 Reads

Transvaginal Ultrasound Vibro-elastography for Measuring Uterine Viscoelasticity: A Phantom Study.

Ultrasound Med Biol 2018 Nov 19. Epub 2018 Nov 19.

Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

The purpose of this research was to determine the feasibility of a transvaginal ultrasound vibro-elastography (TUVE) technique for generating and measuring shear wave propagation in the uterus. In TUVE, a 0.1-s harmonic vibration at a low frequency is generated on the abdomen of a subject via a handheld vibrator. Read More

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November 2018
2 Reads

P21-Activated Kinase 1 Overactivates in Eutopic Endometrium of Adenomyosis.

Reprod Sci 2018 Nov 19:1933719118812737. Epub 2018 Nov 19.

1 Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Adenomyosis is a common gynecological disease, characterized by the existence of endometrium in the myometrium. The pathogenesis of adenomyosis is not fully understood. P21-activated kinase 1 (PAK1) is an effector of small Rho GTPases including CDC42 and RAC1 and plays various roles in cellular biology, especially cytoskeletal remodeling. Read More

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November 2018

Does presence of adenomyosis affect reproductive outcome in IVF cycles? A retrospective analysis of 973 patients.

Reprod Biomed Online 2018 Oct 26. Epub 2018 Oct 26.

Institute of Reproductive Medicine, HB-36/A/3, Salt Lake City, Sector-III, Kolkata, Kolkata 700106, India.

Research Question: Reports on the effect of adenomyosis on assisted reproductive technology (ART) outcomes are conflicting. Does presence of adenomyosis affect reproductive outcome in IVF cycles in women pretreated with gonadotrophin releasing hormone (GnRH) agonist?

Design: In this retrospective cohort study, 973 women were divided into four groups: only endometriosis (n = 355); endometriosis and adenomyosis (n = 88); adenomyosis alone (n = 64); and tubal factor infertility as controls (n = 466). The pregnancy outcome parameters (clinical pregnancy, miscarriage rate, live birth rate) were compared between these groups. Read More

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October 2018
3 Reads
3.020 Impact Factor

A sonographic classification of adenomyosis: interobserver reproducibility in the evaluation of type and degree of the myometrial involvement.

Fertil Steril 2018 Nov;110(6):1154-1161.e3

Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

Objective: To study the interobserver reproducibility of our new ultrasonographic mapping system to define the type and extension of uterine adenomyosis.

Design: Interobserver study involving two observers with different medical backgrounds and gynecological ultrasound experience.

Setting: University hospital. Read More

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November 2018
8 Reads

Clinical anatomy of pelvic pain in women: A Gynecological Perspective.

Clin Anat 2018 Nov 2. Epub 2018 Nov 2.

Department of Anatomical Sciences, St. George's University, St. George's, Grenada, West Indies.

Pelvic pain is a common symptom that affects women worldwide and usually presents with variable range of severity, duration, and location. Several gynecological conditions may result in pelvic pain, and may have a variable presentation among patients. Pelvic pain creates a significant challenge and frustration to both patients and clinicians, which also creates a significant burden on the economy. Read More

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November 2018
1 Read

Correlation of LOX‑5 and COX‑2 expression with inflammatory pathology and clinical features of adenomyosis.

Mol Med Rep 2018 Nov 1. Epub 2018 Nov 1.

Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China.

Adenomyosis is a common benign disease of women of childbearing age. The typical clinical features are prolonged menstruation, menorrhagia and ingravescent dysmenorrhea. In the present study, the severity of dysmenorrhea was assessed using the visual analogue scale system as follows: 0, No pain; 1‑3, minimal pain; 4‑6, moderate pain; and 7‑10, severe pain. Read More

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November 2018
3 Reads

RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis.

J Int Med Res 2018 Nov 2:300060518789038. Epub 2018 Nov 2.

3 Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: This study aimed to investigate RhoA, RhoA-associated coiled-coil containing protein kinase (ROCK) 1, ROCK2, and Rho GTPase-activating protein 26 (ARHGAP26) expression in the eutopic endometrium (EU) and ectopic endometrium (EC), and examine their relationships with the clinical characteristics of adenomyosis.

Methods: Twenty patients with adenomyosis who underwent laparoscopy were recruited. Protein and mRNA expression of RhoA, ROCK1, ROCK2, and ARHGAP26 in EU and EC of patients with adenomyosis and in control endometrium without adenomyosis (CE) was detected. Read More

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November 2018
2 Reads

Ulipristal acetate therapy increases ultrasound features of adenomyosis: a good treatment given in an erroneous diagnosis of uterine fibroids.

Gynecol Endocrinol 2018 Nov 1:1-4. Epub 2018 Nov 1.

a Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic , University of Rome "Tor Vergata" , Roma , Italy.

Ulipristal acetate (UPA) is used for medical treatment of uterine fibroids. The aim of this study was to describe the effects on painful symptoms and the sonographic uterine modifications in patients with adenomyosis erroneously treated with UPA. This is an observational study on six women affected by adenomyosis and treated with three months of UPA (5 mg/24h). Read More

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November 2018
3 Reads

Predisposing factors for predicting the therapeutic response of adenomyosis after uterine artery embolization: serum CA125 levels and accompanying endometriosis.

Diagn Interv Radiol 2018 Nov;24(6):364-371

Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Purpose: We aimed to identify predisposing factors that could help predict the therapeutic response of adenomyosis after uterine artery embolization (UAE).

Methods: This was a retrospective, single-center study of patients admitted to the hospital for adenomyosis between 2013 and 2015. Sixty-eight patients with adenomyosis who underwent UAE with tris-acryl gelatin microspheres were divided into two groups based on their therapeutic response (complete or incomplete necrosis of lesions), and pre- and postprocedural pelvic magnetic resonance imaging (MRI) data. Read More

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November 2018
6 Reads

[Degree of fibrosis of adenomyotic myometrium and its relationship with dysmenorrhea].

Zhonghua Fu Chan Ke Za Zhi 2018 Oct;53(10):689-693

Gynecological Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China.

To investigate degrees of fibrosis of adenomyosis (AM) myometrium and explore its relationship with dysmenorrhea. Thirty AM patients who had hysterectomy from July, 2015 to December, 2016 in Beijing Obstetrics and Gynecology Hospital were selected as AM group; 28 cases of hysterectomy due to cervical lesions (none AM) were selected as control group. The area ratio of collagen fiber in the two groups was analysed by modified Masson stain, and the expression of collagen type Ⅰprotein in the two groups was analysed by immunohistochemical method. Read More

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October 2018
5 Reads

[Effect of gonadotropin-releasing hormone agonist used before surgery on natural pregnancy rates in patients with ovarian endometriomas].

Zhonghua Fu Chan Ke Za Zhi 2018 Oct;53(10):683-688

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To evaluate the impact of gonadotropin-releasing hormone agonist (GnRH-a) used before surgery on natural pregnancy rates in patients with ovarian endometriomas. In this retrospective study, 57 patients with ovarian endometriomas who had a consecutive laparoscopic surgery between June, 2010 to September, 2015 in Peking Union Medical College Hospital were included. Those patients were divided into preoperative GnRH-a treatment group (31) and non-GnRH-a treatment group (26) . Read More

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October 2018
5 Reads

Risk of preterm birth, low birthweight, and small-for-gestational-age infants in pregnancies with adenomyosis: a cohort study of the Japan Environment and Children's Study.

Acta Obstet Gynecol Scand 2018 Oct 26. Epub 2018 Oct 26.

Fukushima Regional Center for the Japan Environmental and Children's Study, Fukushima, Japan.

Introduction: This study evaluated the risk of preterm birth, low birthweight, and small-for-gestational-age neonates born to mothers with adenomyosis during pregnancy.

Material And Methods: We used the results of a Japanese nationwide prospective birth cohort study, identifying 93 668 singleton deliveries from 2011 to 2014. We identified 314 pregnancies with adenomyosis using self-reported questionnaires. Read More

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October 2018
2 Reads

FAK regulates epithelial‑mesenchymal transition in adenomyosis.

Mol Med Rep 2018 Dec 26;18(6):5461-5472. Epub 2018 Oct 26.

Department of Gynecology Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100000, P.R. China.

Epithelial‑mesenchymal transition (EMT) has been associated with the pathogenesis of adenomyosis; focal adhesion kinase (FAK) serves an important role in the EMT process. The aim of the present study was to determine whether FAK regulates EMT in adenomyosis and to investigate the potential pathway in this process. The expression of FAK and EMT‑associated molecules in adenomyosis and control cells were determined by immunohistochemical staining and immunofluorescence at the protein level, and at the mRNA level by reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR). Read More

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December 2018
10 Reads

Endometrial receptivity and adenomyosis.

Authors:
Peng-Hui Wang

Taiwan J Obstet Gynecol 2018 10;57(5):625-626

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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October 2018

Clinical Manifestations of Adenomyosis Patients with or without Coexisting Endometriosis.

Chin Med J (Engl) 2018 Oct;131(20):2495-2498

Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

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October 2018

Expression of Nerve Injury-Induced Protein1 (Ninj1) in Endometriosis.

Reprod Sci 2018 Oct 16:1933719118806395. Epub 2018 Oct 16.

1 Department of Obstetrics and Gynecology, The University of Tokyo, Tokyo, Japan.

Objective: The aim of this study was to clarify the expression of Ninj1 in endometriosis and adenomyosis lesions, and its inductive factor in human endometriotic stromal cells (ESCs).

Background: Nerve injury-induced protein 1 (Ninj1) is a molecule originally identified in dorsal root ganglion neurons and Schwann cells after nerve injury and promotes neurite outgrowth. The aim of this study was to clarify the expression of Ninj1 in endometriosis and adenomyosis lesions, and its inductive factor in human endometriotic stromal cells (ESCs). Read More

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October 2018

Effects of adenomyosis on obstetric outcomes: a literature review.

Minerva Ginecol 2018 Oct 11. Epub 2018 Oct 11.

Policlinico Abano Terme, Abano Terme, Padua, Italy.

Introduction: Several studies investigated the correlation between adenomyosis and adverse pregnancy outcomes. However, the role of adenomyosis as a risk factor for adverse outcomes in has yet to be established. The aim of this systematic review is to clarify the possible association between uterine adenomyosis and poor obstetrical outcomes. Read More

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October 2018
10 Reads

Two- and three-dimensional ultrasonographic features related to histopathology of the uterine endometrial-myometrial junctional zone.

Acta Obstet Gynecol Scand 2018 Oct 14. Epub 2018 Oct 14.

Department of Gynecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark.

Introduction: Our aim was to correlate junctional zone thickening and irregularity (junctional zone disease) and other ultrasonographic features of adenomyosis with the histopathology of the endometrial-myometrial junctional zone.

Material And Methods: Consecutively enrolled premenopausal women (n = 110) scheduled for hysterectomy or transcervical endometrial resection due to abnormal uterine bleeding and/or menstrual pain, underwent two- and three-dimensional transvaginal ultrasonography on the day of surgery with the observer blinded to previous diagnosis. Junctional zone maximum thickness (JZ ), junctional zone maximum irregularity (JZ ) and ultrasonographic characteristics of adenomyosis were compared with histopathology of the junctional zone defined as (1) adenomyosis of the inner myometrium, ≥2 mm myometrial invasion without contact to the basal endometrium, (2) serrated junctional zone, >3 mm myometrial invasion with contact to the basal endometrium or (3) linear junctional zone, no or marginal myometrial invasion ≤3 mm with contact to the basal endometrium. Read More

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October 2018
2 Reads

Development of a clinical prediction model for diagnosing adenomyosis.

Fertil Steril 2018 Oct;110(5):957-964.e3

Department of Gynecology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Objective: To develop a multivariate prediction model for diagnosing adenomyosis using predictors available through transvaginal ultrasonography and clinical examinations.

Design: Prospective observational single-center study.

Setting: Teaching university hospital. Read More

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October 2018
1 Read

A new era in diagnosing adenomyosis is coming.

Fertil Steril 2018 Oct;110(5):858

Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic, University of Rome "Tor Vergata", Rome, Italy.

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October 2018
2 Reads

Magnetic resonance imaging features influencing high-intensity focused ultrasound ablation of adenomyosis with a nonperfused volume ratio of ≥90% as a measure of clinical treatment success: retrospective multivariate analysis.

Int J Hyperthermia 2018 Oct 11:1-11. Epub 2018 Oct 11.

c Department of Radiology , Pham Ngoc Thach University of Medicine , Ho Chi Minh City , Viet Nam.

Objective: This retrospective study aimed (1) to investigate the magnetic resonance imaging (MRI) features influencing a nonperfused volume ratio (NPVr) ≥ 90% after high-intensity focussed ultrasound (HIFU) ablation of adenomyosis, and (2) to assess the safety, which was defined in terms of adverse events (AEs) and changes in anti-Mullerian hormone (AMH) concentrations, and clinical efficacy, which was defined in terms of adenomyosis volume reduction and symptom improvement at 6 months' follow-up.

Methods: Sixty-six women who underwent HIFU treatment were divided into groups A (NPVr ≥90%; n = 26) and B (NPVr <90%, n = 40). Multivariate logistic regression analyses of MRI features were conducted to identify the potential predictors of an NPVr ≥90%. Read More

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October 2018
2 Reads

High intensity focused ultrasound treatment of adenomyosis: a comparative study.

Int J Hyperthermia 2018 Oct 11:1-5. Epub 2018 Oct 11.

a Department of Gynecology , The First Hospital of Shijiazhuang , Shijiazhuang , China.

Objective: To compare the treatment efficacy and safety of high intensity focused ultrasound (HIFU) on its own, HIFU combined with levonorgestrel-releasing intrauterine system (LNG-IUS) and HIFU combined with gonadotropin-releasing hormone agonist (GnRHa).

Method: Seventy-eight patients with adenomyosis who underwent HIFU treatment were retrospectively analyzed. Among them, 45 patients were treated only with HIFU, 15 patients were treated with HIFU combined with LNG-IUS and 18 patients were treated with HIFU combined with GnRHa. Read More

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October 2018
2 Reads
2.640 Impact Factor

Comparison of effectiveness of epidural analgesia and monitored anesthesia care for high-intensity focused ultrasound treatment of adenomyosis.

Int J Hyperthermia 2018 Oct 10:1-9. Epub 2018 Oct 10.

a Department of Anesthesiology and Pain Medicine , Seoul National University Hospital , Seoul , Republic of Korea.

Background: High-intensity focused ultrasound (HIFU) is a noninvasive thermodestructive procedure targeting internal organs with concentrated sonification energy that may cause pain. We aimed to compare the effectiveness of epidural analgesia (EA) and monitored anesthesia care (MAC) in HIFU treatment of uterine adenomyosis.

Materials And Methods: Sixty-eight patients were included in this case-control study. Read More

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October 2018
1 Read

Assessment of ovarian reserve after cystectomy versus 'one-step' laser vaporization in the treatment of ovarian endometrioma: a small randomized clinical trial.

Hum Reprod 2018 Dec;33(12):2205-2211

Endocrinological Gynecology Department, Jagiellonian University, Collegium Medicum, Cracow, Poland.

Study Question: Does CO2 laser vaporization offer better results in treating endometrioma in terms of ovarian reserve preservation compared to traditional cystectomy?

Summary Answer: Assessing both antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) levels as measures of ovarian reserve, the results suggest that CO2 technology may be an alternative treatment for endometrioma, causing minimal damage to adjacent healthy ovarian tissue.

What Is Known Already: Excisional surgery has been questioned as an ideal surgical approach for endometriomas because it is associated with potential reduction of ovarian reserve. Recently, vaporization with CO2 laser in-line-of-sight, according to the 'three-step procedure', has been proposed as the best method to preserve ovarian function. Read More

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December 2018
6 Reads

Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases.

BMC Neurol 2018 Oct 4;18(1):166. Epub 2018 Oct 4.

Department of Neurosurgery, Yamaguchi University School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan.

Background: Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic stroke that seemed to be caused by mucin-producing adenomyosis. Read More

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October 2018
8 Reads

OC01: Transvaginal ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis.

Ultrasound Obstet Gynecol 2018 Oct;52(4):555

Department of Obstetrics & Gynecology, University General Hospital Alexandroupolis, Alexandroupoli, Greece.

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October 2018
17 Reads

Bladder Endometriosis: Management by Cystoscopic and Laparoscopic Approaches.

J Minim Invasive Gynecol 2018 Sep 29. Epub 2018 Sep 29.

Jyoti Hospital & Minimal Invasive Surgery Center, Ahmedabad, India (all authors).

Study Objective: Endometriosis of the urinary system accounts for less than 1% of all endometriosis, wherein bladder endometriosis is the most common. Bladder endometriosis is defined as endometriosis infiltrating the detrusor muscle and represents 85% of urinary tract endometriosis [1,2]. Segmental bladder resection/partial cystectomy is the bladder-preserving surgery and offers the complete removal of bladder endometriotic nodules [3,4]. Read More

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September 2018
3 Reads

The Association of Sonographic Evidence of Adenomyosis with Severe Endometriosis and Gene Expression in Eutopic Endometrium.

J Minim Invasive Gynecol 2018 Sep 28. Epub 2018 Sep 28.

Gynaecology Research Centre, Department of Obstetrics and Gynaecology, The University of Melbourne and Royal Women's Hospital, Parkville, Australia (Drs. Rogers, Holdsworth-Carson, and Girling).

Study Objective: To examine the presence of sonographic evidence of adenomyosis (SEOA) in patients undergoing laparoscopic surgery for the investigation of endometriosis and to assess if there is an association between SEOA and endometriosis severity. Using gene expression analysis, we also aimed to determine if gene expression in eutopic endometria differed in patients with and without adenomyosis.

Design: A prospective study (Canadian Task Force classification II-2). Read More

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September 2018
2 Reads

Incarceration of early gravid uterus with adenomyosis and myoma: report of two patients managed with uterine reduction.

Obstet Gynecol Sci 2018 Sep 2;61(5):621-625. Epub 2018 Aug 2.

Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.

Although gravid uterine incarceration is typically diagnosed during the early second trimester, we encountered two unusual cases in early pregnancy. A 34-year-old multiparous woman with adenomyosis presented at 7 + 2 weeks of gestation with increased urinary frequency and a sensation of incomplete bladder emptying. The uterine incarceration was successfully reduced by manual reduction and pessary insertion, and she delivered a normal infant at term. Read More

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September 2018
5 Reads

Efficacy of Hormonal Therapies for Decreasing Uterine Volume in Patients with Adenomyosis.

Gynecol Minim Invasive Ther 2018 Jul-Sep;7(3):119-123. Epub 2018 Aug 23.

Department of Obstetrics and Gynecology, Nippon Medical School, Tokyo, Japan.

Study Objective: The aim of this study is to evaluate the efficacy of hormonal therapies for inhibiting an increase in uterine volume in patients with adenomyosis.

Design: This was retrospective cohort study.

Setting: This study was conducted at Nippon Medical School Musashikosugi Hospital. Read More

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August 2018
2 Reads

Transvaginal Natural Orifice Transluminal Endoscopic Surgery Hysterectomy in a Woman with Uterine Adenomyosis and Multiple Severe Abdominal Adhesions.

Gynecol Minim Invasive Ther 2018 Apr-Jun;7(2):70-73. Epub 2018 May 2.

Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan.

Natural orifice transluminal endoscopic surgery (NOTES) had been used for many gynecologic surgeries without pelvic adhesions. We report a 30-year-old female with multiple abdominal adhesions underwent NOTES hysterectomy successfully. A 30-year-old female (para 2, gravida 3, abortus 1) presented with menorrhagia and dysmenorrhea. Read More

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May 2018
6 Reads

Subtotal hysterectomy by natural orifice transluminal endoscopic surgery.

Gynecol Minim Invasive Ther 2017 Oct-Dec;6(4):195-198. Epub 2017 May 4.

Department of Obstetrics and Gynecology, Linkou Chang Gung Memorial Hospital, Kwei-Shan, Taoyuan, Taiwan.

Study Objective: To introduce the innovative surgical procedure of treating benign uterine pathology with subtotal hysterectomy by natural orifice transluminal endoscopic surgery (NOTES).

Design: Prospective observational study.

Setting: Tertiary referral medical center. Read More

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May 2017
7 Reads

Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report.

Case Rep Obstet Gynecol 2018 4;2018:6210172. Epub 2018 Sep 4.

Department of Obstetrics and Gynecology, Kanazawa Medical University, School of Medicine, Japan.

Dienogest (DNG) is considered to be effective against ovarian endometrioma (OMA). We report a rare case of OMA transformation to ovarian cancer during long-term endometriosis treatment with a periodic administration of a gonadotropin-releasing hormone agonist (Gn-RH agonist) and DNG. The patient was a 41-year-old Japanese woman. Read More

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September 2018
3 Reads

Adenomyosis: A Sonographic Diagnosis.

Radiographics 2018 Sep-Oct;38(5):1576-1589

From the Department of Radiology, Einstein Healthcare Network, 5501 Old York Rd, Philadelphia, PA 19141.

Adenomyosis is a common benign uterine condition and a frequent cause of pelvic pain in premenopausal women. Transvaginal US is now considered the primary imaging modality for the diagnosis of adenomyosis, and thus radiologists should be familiar with its sonographic appearance. US findings can be divided into three categories, which parallel the histology of adenomyosis: (a) ectopic endometrial glands and stroma, (b) muscular hyperplasia/hypertrophy, and (c) increased vascularity. Read More

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September 2018
12 Reads

Persistence of Symptoms After Total vs Supracervical Hysterectomy in Women with Histopathological Diagnosis of Adenomyosis.

J Minim Invasive Gynecol 2018 Sep 8. Epub 2018 Sep 8.

Division of Minimally Invasive Gynecologic Surgery (Drs. Ajao, Oliveira Brito, Wang, Einarsson, and Cohen and Ms. Cox, Ms. Meurs, Ms. Goggins, and Ms Gu) and Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

Study Objective: To compare symptom persistence in women with adenomyosis based on retention or removal of the cervix at the time of hysterectomy.

Design: Retrospective cohort study and follow-up survey (Canadian Task Force classification xx).

Setting: Tertiary care academic hospital in Boston, Massachusetts. Read More

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September 2018
4 Reads

Multiple Synchronous Lesions in the Genital Tract of a Female: A Rare Combination with Unrelated Histogenesis.

J Menopausal Med 2018 Aug 31;24(2):133-137. Epub 2018 Aug 31.

Department of Pathology, MES Medical College, Perinthalmanna, Kerala, India.

Presenting a case of endometrioid adenocarcinoma of the endometrium, benign cystic teratoma of one ovary, fibrothecoma in the other ovary and adenomyosis in the uterus. Such a combination of synchronous lesion is very rare and is not reported in the English medical literature. Read More

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August 2018
2 Reads

The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions.

Int J Gynaecol Obstet 2018 Dec 10;143(3):393-408. Epub 2018 Oct 10.

School of Women's and Children's Health, Royal Hospital for Women, University of New South Wales, Randwick, NSW, Australia.

Background: The International Federation of Gynecology and Obstetrics (FIGO) systems for nomenclature of symptoms of normal and abnormal uterine bleeding (AUB) in the reproductive years (FIGO AUB System 1) and for classification of causes of AUB (FIGO AUB System 2; PALM-COEIN) were first published together in 2011. The purpose was to harmonize the definitions of normal and abnormal bleeding symptoms and to classify and subclassify underlying potential causes of AUB in the reproductive years to facilitate research, education, and clinical care. The systems were designed to be flexible and to be periodically reviewed and modified as appropriate. Read More

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December 2018
47 Reads

Preserving fertility by treating the three compartments: laparoscopic approach to deep infiltrating endometriosis.

J Minim Invasive Gynecol 2018 Sep 5. Epub 2018 Sep 5.

Service de Chirurgie Gynécologique, Hôpitaux Universitaires, Strasbourg, France.

Study Objective: To describe a laparoscopic technique for the resection of deep endometriosis, treating the three compartments.

Design: Educational video SETTING: Tertiary referral center in Strasbourg, France PATIENTS: This is the case of a 37-year-old primiparous woman. Her main symptoms included dysmenorrhea and dyspareunia associated with pollakiuria and macroscopic menstrual hematuria (with emission of endometriotic tissue on analysis). Read More

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September 2018
5 Reads

Inter-rater agreement in the diagnosis of adenomyosis by 2- and 3-dimensional transvaginal ultrasonography.

J Ultrasound Med 2018 Sep 4. Epub 2018 Sep 4.

Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.

Objectives: To assess the inter-rater agreement of 2-dimensional (2D) and 3-dimensional (3D) transvaginal ultrasonography (TVUS) in the diagnosis of adenomyosis.

Methods: This prospective study included premenopausal women (n = 96) with heavy menstrual bleeding, menstrual pain, or both who were scheduled for hysterectomy or transcervical resection of the endometrium. All women underwent real-time 2D TVUS and subsequently offline 3D TVUS, which was blinded to 2D TVUS, by a single expert rater and a single nonexpert rater for the diagnosis of adenomyosis based on standardized pattern recognition and junctional zone measurements. Read More

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September 2018

Adenomyosis and Myomata: Risks, Problems, and Complications in Diagnosis and Therapy of Adenomyosis and Myomata.

Biomed Res Int 2018;2018:5952460. Epub 2018 Aug 6.

Department of Obstetrics and Gynecology, Goethe University Frankfurt, Frankfurt, Germany.

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Treatment of Adenomyosis with Subcutaneous Etonogestrel Implants: A Clinical Observational Study in 17 Patients.

Med Sci Monit 2018 Sep 1;24:6085-6092. Epub 2018 Sep 1.

Department of Obstetrics and Gynecology, The First Affiliated Hospital and Clinical College of Fujian Medical University, Fuzhou, Fujian, China (mainland).

BACKGROUND Adenomyosis is a cause of chronic pelvic pain in women of reproductive age. The aim of this study was to investigate the effects of subcutaneous etonogestrel implantation on adenomyosis. MATERIAL AND METHODS A clinical observational study included 17 women with adenomyosis who were treated with subcutaneous etonogestrel implants and followed-up for 12 months. Read More

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September 2018
9 Reads

Accessory cavitated uterine mass: MRI features and surgical correlations of a rare but under-recognised entity.

Eur Radiol 2018 Aug 29. Epub 2018 Aug 29.

Radiology Department, Lyon Sud University Hospital, Hospices Civils de Lyon, 165 Chemin du Grand Revoyet, 69495, Pierre Bénite, France.

Objectives: To describe MRI features of accessory cavitated uterine mass (ACUM) with surgical correlations.

Methods: Eleven young women with an ACUM at pathology underwent preoperative pelvic MRI. Two experienced radiologists retrospectively analysed MR images in consensus to determine the lesion location within the uterus, its size, morphology (shape and boundaries), and structure reporting the signal and enhancement of its different parts compared to myometrium. Read More

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August 2018
3 Reads

Clear Cell Carcinoma Arising in Vulvar Endometriosis.

Case Rep Pathol 2018 26;2018:4263104. Epub 2018 Jul 26.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Thailand.

We report a case of vulvar clear cell adenocarcinoma in a woman presenting with a lump and pain in the right side of the labia majora. Three years prior to this visit, she underwent a total abdominal hysterectomy with bilateral salpingooophorectomy and excision of a labial mass. Pathological examination revealed adenomyosis and multiple leiomyomas in the uterus, endometriotic cysts in both ovaries, and foci of atypical endometriosis in the labial mass. Read More

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July 2018
10 Reads

"Recurrent multiple cerebral infarctions related to the progression of adenomyosis: a case report".

BMC Neurol 2018 Aug 21;18(1):119. Epub 2018 Aug 21.

Department of Neurology, Faculty of Medicine, Oita University, Yufu-city, Oita, 879-5593, Japan.

Background: Benign gynecologic tumor, such as uterine adenomyosis, has been suggested to develop hypercoagulability. Although some cases of cerebral infarction associated with adenomyosis have been reported, the mechanism of hypercoagulation initiated by adenomyosis is still not clear, and the therapeutic strategy is uncertain.

Case Presentation: A 44-year-old woman was presented to our department with headache, left hand weakness, and gait disturbance during her menstrual phase. Read More

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August 2018
2 Reads