1,354 results match your criteria Adenoma Bronchial


Well-differentiated fetal adenocarcinoma of the lung: positron emission tomography features and diagnostic difficulties in frozen section analysis-a case report.

Surg Case Rep 2020 Jun 29;6(1):152. Epub 2020 Jun 29.

Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Background: Well-differentiated fetal adenocarcinoma (WDFA) of the lung is a rare disease that resembles fetal lung tubules. Most of previous reports concerning WDFA have focused on histological features, while there are few reports describing radiological features. In addition, there are no reports evaluating the difficulty of intraoperative diagnosis of WDFA with frozen section. Read More

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http://dx.doi.org/10.1186/s40792-020-00910-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324441PMC

Persistent hyperparathyroidism due to mediastinal parathyroid adenoma treated with selective arterial embolization with embosphere: first case in the literature.

Authors:
G Yuce N C Seyrek

Osteoporos Int 2020 Jun 5. Epub 2020 Jun 5.

Endocrinology and Metabolism Department, Ankara Yildirim Beyazit University, Ankara, Turkey.

Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia in the clinical setting and affects 0.3% of the population. Parathyroidectomy is the only definitive cure. Read More

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http://dx.doi.org/10.1007/s00198-020-05456-3DOI Listing

Histologic characteristics and prognosis of lung mixed squamous cell and glandular papilloma: six case reports.

Int J Clin Exp Pathol 2019 1;12(9):3542-3548. Epub 2019 Sep 1.

Department of Clinical Laboratory, The Fourth Hospital of Hebei Medical University Shijiazhuang, China.

Lung mixed squamous cell and glandular papilloma (LMSCGP) has no clear signs, clinical symptoms, or imaging features; thus, its diagnosis primarily relies on post-resection histology and immunohistochemistry. Therefore, in this work six case reports are described to review the clinicopathologic characteristics, diagnosis, treatment, and prognosis. Here, we report the clinical symptoms, imaging features, pathologic characteristics, and follow-up data of six LMSCGP patients. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949857PMC
September 2019

La néoplasie endocrinienne multiple de type 1 : mise au point après le congrès de l’ENETS 2019: Multiple Endocrine Neoplasia Type 1: Development after the ENETS 2019 Congress.

Ann Endocrinol (Paris) 2019 Sep;80 Suppl 1:S19-S28

Service endocrinologie et maladies métaboliques, pôle cardio-vasculaire et métabolique, CHU Larrey-Rangueil, Toulouse, France.

Multiple Endocrine Neoplasia Type 1 (NEM1) is related to mutations of the menin gene. It is an autosomal dominant disease. Its prevalence is about 1/30 000 with a hugh penetrance. Read More

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http://dx.doi.org/10.1016/S0003-4266(19)30113-1DOI Listing
September 2019
1 Read

Adenoid Cystic Carcinoma of the Trachea: A Case Report.

Am J Case Rep 2019 Sep 17;20:1373-1377. Epub 2019 Sep 17.

Faculty of Medicine and Health of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

BACKGROUND Adenoid cystic carcinoma of trachea (ACCT) is an unusual low-grade tumor from the tracheal and bronchial wall glands. The histological structure and biological behavior of ACCT are similar to that of tumors found in the salivary glands. ACCT occurs most commonly in the upper trachea, being found in the articular cartilage in the posterior aspect of the trachea. Read More

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http://dx.doi.org/10.12659/AJCR.917136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767944PMC
September 2019
7 Reads

How thoracic surgeon manage tracheal tumors in African country? (Case series).

Ann Med Surg (Lond) 2019 Aug 18;44:13-19. Epub 2019 Jun 18.

Department of Thoracic Surgery, CHU Hassan II, Fez, Morocco.

Introduction: Tracheal tumors are a rare pathological entity whose diagnosis is usually delayed by clinical latency. Surgery, which consists of a tracheal resection-anastomosis with or without reconstructive reconstruction, remains the treatment that ensures the best long-term survival.

Methods: This is a retrospective study about 8 patients admitted in the department of thoracic surgery of Hassan II's university hospital of Fes for tracheal tumors management during 7 years time (December 2010 to December 2017). Read More

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http://dx.doi.org/10.1016/j.amsu.2019.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593208PMC
August 2019
7 Reads

Extra-pleural pneumonectomy in the era of image-guided intensity-modulated radiotherapy.

Radiol Med 2019 Sep 8;124(9):854-859. Epub 2019 Apr 8.

Department of Radiation Oncology, Azienda Ospedaliero Universitaria Careggi, University of Florence, Largo Brambilla, 3, 50134, Florence, Italy.

Purpose: To assess the outcome of malignant pleural mesothelioma patients treated with extra-pleural pneumonectomy (EPP) and adjuvant radiotherapy (RT), using the most advanced radiotherapeutic techniques, namely image-guided intensity-modulated RT (IG-IMRT).

Methods And Materials: Fifty-four patients were analyzed. Minimum radiation dose was 50 Gy (2 Gy/fr). Read More

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http://link.springer.com/10.1007/s11547-019-01030-y
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http://dx.doi.org/10.1007/s11547-019-01030-yDOI Listing
September 2019
22 Reads

Diagnostics and acknowledgement of occupational diseases - topics and challenges in the Czech Republic.

Cas Lek Cesk 2018 Dec;157(8):396-399

The causes of occupational diseases are changing, thats why a regular update of Czech List of Occupational Diseases is needed. New compensable occupational diseases, such as cancer of the larynx and ovarian cancer due to asbestos, and chronic obstructive pulmonary diseases due to black coal dust were included in the last two updates of the Czech List. The need of an early examination at the Centers of Occupational Diseases is stressed in this article, especially before a surgery or other treatment of epicondylitis and carpal tunnel syndrome. Read More

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December 2018
12 Reads

Right main bronchial pleomorphic adenoma: A case report and literature review.

Medicine (Baltimore) 2018 Oct;97(42):e12648

Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Respiratory Medicine Center of Fujian Province, Licheng District, Quan Zhou, P.R. China.

Rationale: Tracheobronchial benign tumors are uncommon; particularly, bronchial pleomorphic adenoma is one of the rarest benign tumors that develop in bronchus (only 7 reported cases, among which only 4 cases of pleomorphic adenoma were seen arising from right main bronchus).

Patient Concerns: In this report, a 38-year-old woman suffered from progressive shortness of breath for 5 years due to right main bronchial pleomorphic adenoma.

Diagnoses: The patient was diagnosed as right main bronchial pleomorphic adenoma based on chest computed tomography enhanced scan, bronchoscopy, and histological examination. Read More

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http://dx.doi.org/10.1097/MD.0000000000012648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211913PMC
October 2018
35 Reads

A case of ectopic ACTH syndrome due to DDAVP-sensitive but V1b receptor-negative bronchial typical carcinoid with lymphatic metastasis and plasma ProGRP elevation.

Endocr J 2018 Dec 20;65(12):1161-1169. Epub 2018 Sep 20.

Department of Diabetes and Endocrinology, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan.

Ectopic ACTH syndrome (EAS) is a potentially fatal endocrine disease that results from a variety of neuroendocrine tumors (NETs), such as small cell lung cancer (SCLC) and bronchial typical carcinoid. Typical carcinoid is usually slow growing, not associated with plasma progastrin releasing peptide (ProGRP) elevation. Here, we report a 47-year-old female smoker with progressive typical carcinoid and plasma ProGRP elevation. Read More

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http://dx.doi.org/10.1507/endocrj.EJ18-0052DOI Listing
December 2018
13 Reads

A rare case of peripherally located non-bronchial pulmonary mucous gland adenoma.

Turk Gogus Kalp Damar Cerrahisi Derg 2018 Oct 16;26(4):664-667. Epub 2018 Sep 16.

Department of Pathology, Medicine Faculty of Sanko University, Gaziantep, Turkey.

Pulmonary mucous gland adenomas are rare benign tumors, which need to be differentiated from malign lung masses. The differential diagnosis is of particular importance for those arising from lung parenchyma in atypical locations. In this article, we report a 70-year-old male patient, who had complaints of cough and expectoration for almost two years. Read More

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http://dx.doi.org/10.5606/tgkdc.dergisi.2018.15357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018175PMC
October 2018

Paragonimus westermani infection manifesting as a pulmonary cavity and adrenal gland mass: A case report.

J Infect Chemother 2019 Mar 10;25(3):200-203. Epub 2018 Sep 10.

Department of Internal Medicine, Keimyung University School of Medicine, Dongsan Medical Center, Republic of Korea. Electronic address:

We report a case of Paragonimus westermani infection simultaneously affecting two separate organs that presented as both a pulmonary cavity and adrenal mass in an immunocompromised host. A 65-year-old male with a previous kidney transplant visited our clinic because of hemoptysis. Chest computed tomography (CT) showed a pulmonary cavity and right adrenal gland mass. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.08.005DOI Listing
March 2019
13 Reads

Tracheal pleomorphic adenoma with coexisting pulmonary tuberculoma.

Yeungnam Univ J Med 2018 06 30;35(1):114-120. Epub 2018 Jun 30.

Department of Pulmonary and Critical Care Medicine, Kosin University Gospel Hospital, Kosin University College of Medicine, Busan, Korea.

Tracheal tumors are rare and difficult to diagnose. Moreover, delays in diagnosis are very common because the symptoms are nonspecific. As a result, tracheal tumors are commonly mistreated as chronic obstructive pulmonary disease or bronchial asthma. Read More

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http://dx.doi.org/10.12701/yujm.2018.35.1.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784665PMC
June 2018
1 Read

Adenolipoma of the Bronchus. A Rare Entity.

Am J Respir Crit Care Med 2018 02;197(4):520-521

1 Division of Critical Care Medicine.

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http://dx.doi.org/10.1164/rccm.201710-2003IMDOI Listing
February 2018
13 Reads

Bronchial oncocytosis: An incidental finding in ultrasound-guided transbronchial fine-needle aspiration cytology.

Diagn Cytopathol 2018 01 19;46(1):101-102. Epub 2017 Oct 19.

Department of Pathology, Hospital Universitario La Princesa, Madrid, Spain.

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http://doi.wiley.com/10.1002/dc.23846
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http://dx.doi.org/10.1002/dc.23846DOI Listing
January 2018
9 Reads

Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study.

BMJ Open 2017 Oct 11;7(10):e017104. Epub 2017 Oct 11.

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-Universität Bochum (IPA), Bochum, Germany.

Objectives: Mesothelin and calretinin are blood-based markers for malignant mesothelioma. The objective of this study was to analyse the markers in plasma samples from cancer-free men and to identify factors influencing their concentrations to minimise false-positive test results when using these markers for the early detection of malignant mesothelioma.

Setting: The present analyses used data and archived blood samples of the population-based Heinz Nixdorf Recall Study among elderly people collected from 2011 to 2014. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-017104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652464PMC
October 2017
39 Reads

Impact of etiology, age and gender on onset and severity of hyponatremia in patients with hypopituitarism: retrospective analysis in a specialised endocrine unit.

Endocrine 2017 Nov 14;58(2):312-319. Epub 2017 Sep 14.

Department of Neuroendocrinology, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Belgrade, Serbia.

Background: Hyponatremia can unmask hypopituitarism and secondary adrenal insufficiency. This is important, since the need to screen for steroid deficiency, in patients with hyponatremia is often neglected.

Patients And Methods: In a retrospective study, twenty-five patients (13f/12m, age 58. Read More

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http://dx.doi.org/10.1007/s12020-017-1415-1DOI Listing
November 2017
58 Reads

The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model.

Cancer Prev Res (Phila) 2017 Nov 29;10(11):671-679. Epub 2017 Aug 29.

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Prostacyclin (prostaglandin I, PGI) overproduction in FVB/N mice prevents the formation of carcinogen and tobacco smoke-induced adenomas, and administration of the oral prostacyclin analogue iloprost to wild-type mice also prevented carcinogen-induced mouse lung adenoma formation. Former smokers taking oral iloprost showed improved bronchial dysplasia histology compared with placebo. Next-generation oral prostacyclin analogues, like treprostinil, were developed for the treatment of pulmonary arterial hypertension (PAH). Read More

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http://dx.doi.org/10.1158/1940-6207.CAPR-17-0050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769875PMC
November 2017
20 Reads

Cushing Syndrome: Diagnostic Workup and Imaging Features, With Clinical and Pathologic Correlation.

AJR Am J Roentgenol 2017 Jul;209(1):19-32

1 Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.

Objective: Cushing syndrome (CS) is a constellation of clinical signs and symptoms resulting from chronic exposure to excess cortisol, either exogenous or endogenous. Exogenous CS is most commonly caused by administration of glucocorticoids. Endogenous CS is subdivided into two types: adrenocorticotropic hormone (ACTH) dependent and ACTH independent. Read More

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http://dx.doi.org/10.2214/AJR.16.17290DOI Listing
July 2017
48 Reads

Bronchial mucous gland adenoma: A rare tumor.

Rev Port Pneumol (2006) 2017 Jul - Aug;23(4):241-242. Epub 2017 May 27.

Serviço de Pneumologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.rppnen.2017.04.006DOI Listing
January 2019
21 Reads

[Malignant Pleural Mesothelioma Presenting Refractory Pneumothorax Successfully Treated by Intrapleural Administration of Diluted Fibrin Glue;Report of a Case].

Kyobu Geka 2017 May;70(5):393-396

Department of Thoracic, Endocrine Surgery and Oncology, University of Tokushima Graduate School, Tokushima, Japan.

Malignant pleural mesothelioma sometimes accompanies intractable neumothorax due to the visceral pleural invasion of the tumor. A 68-years-old man was found to have massive pleural effusion and pleural mass combined with pneumothorax by computed tomography(CT). CT guided biopsy revealed the mass to be malignant pleural mesothelioma. Read More

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May 2017
70 Reads

Inhibition of pulmonary carcinoma proliferation or metastasis of miR-218 via down-regulating CDCP1 expression.

Eur Rev Med Pharmacol Sci 2017 04;21(7):1502-1508

Department of Cardiac Surgery, GuiZhou Province People's Hospital, Guiyang, China.

Objective: Pulmonary carcinoma is one common malignant tumor with a high risk of recurrence and metastasis. Non-small cell lung cancer (NSCLC) is the most common subtype. As one tumor biomarker, microRNA (miR) has tissue sensitivity and can facilitate oncogene or inhibit tumor suppressor gene. Read More

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April 2017
9 Reads

[A bronchial mucous gland adenoma resected by endoscopic procedure].

Rev Mal Respir 2017 Mar 22;34(3):253-256. Epub 2017 Mar 22.

Service de pneumologie, université d'Angers, CHU d'Angers, 49000 Angers, France.

Introduction: Surgical resection is usually performed for the treatment of endobronchial tumors. This case describes the use of endoscopic resection as an initial treatment, allowing to spare lung parenchyma.

Case Report: A patient was admitted to the emergency unit with right lower lobe pneumonia. Read More

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http://dx.doi.org/10.1016/j.rmr.2016.07.008DOI Listing
March 2017
21 Reads

Is Routine Screening of Young Asymptomatic MEN1 Patients Necessary?

World J Surg 2017 08;41(8):2026-2032

Department of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Baldingerstrasse, 35041, Marburg, Germany.

Background: Recent clinical practice guidelines recommend that routine screening of MEN1 mutation carriers should start at the age of 5 years. The occurrence of clinically relevant MEN1 organ manifestations in children (≤18 years) was evaluated.

Methods: Two prospective collected databases of MEN1 patients (n = 166) who underwent annual screening were retrospectively analyzed for organ manifestations in MEN1 patients ≤18 years. Read More

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http://dx.doi.org/10.1007/s00268-017-3992-9DOI Listing
August 2017
39 Reads

Diagnostic challenges and management of a patient with acromegaly due to ectopic growth hormone-releasing hormone secretion from a bronchial carcinoid tumour.

Endocrinol Diabetes Metab Case Rep 2017 6;2017. Epub 2017 Jan 6.

Leeds Centre for Diabetes and Endocrinology , St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds , UK.

A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test. His acromegaly was originally considered to be of pituitary origin, based on a CT scan, which was interpreted as showing a pituitary macroadenoma. Despite two trans-sphenoidal surgeries, cranial radiotherapy and periods of treatment with bromocriptine and octreotide, his acromegaly remained active clinically and biochemically. Read More

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http://dx.doi.org/10.1530/EDM-16-0104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292981PMC
January 2017
38 Reads

An Unusual Cause of Dyspnea.

Ann Thorac Surg 2016 Oct;102(4):e333-4

Department of Surgery, Danbury Hospital, Danbury, Connecticut.

Sialadenoma papilliferum is a tumor of salivary gland origin. It is believed that sialadenoma papilliferum is a benign lesion usually known to occur in the hard palate, retromolar fat pads, lips, and parotid glands. Its origin in the bronchial tree is an extremely rare occurrence. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2016.02.051DOI Listing
October 2016
19 Reads

Pathology Report: Presacral Noncommunicating Enteric Duplication Cyst.

Cancer Control 2016 Apr;23(2):170-4

Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL 33612, USA.

Background: Gastrointestinal (GI) tract duplication cysts or enteric duplication cysts are rare congenital malformations sometimes found on the mesenteric aspect of segments of the alimentary tract. Enteric duplication cysts are lined by normal GI epithelium and may be classified as foregut, mid-gut, and hindgut cysts. Except in very rare cases of retroperitoneal enteric duplication cysts, these cysts communicate with the GI tract and share a common blood supply. Read More

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https://moffitt.org/media/5069/170.pdf
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http://dx.doi.org/10.1177/107327481602300213DOI Listing
April 2016
14 Reads

Photodynamic Therapy in Non-Gastrointestinal Thoracic Malignancies.

Int J Mol Sci 2016 Jan 21;17(1). Epub 2016 Jan 21.

Division of Thoracic Surgery, University of Toronto, Toronto, ON M5G 2C4, Canada.

Photodynamic therapy has a role in the management of early and late thoracic malignancies. It can be used to facilitate minimally-invasive treatment of early endobronchial tumours and also to palliate obstructive and bleeding effects of advanced endobronchial tumours. Photodynamic therapy has been used as a means of downsizing tumours to allow for resection, as well as reducing the extent of resection necessary. Read More

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http://www.mdpi.com/1422-0067/17/1/135
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http://dx.doi.org/10.3390/ijms17010135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730374PMC
January 2016
54 Reads

[Salivary gland-type lung tumor: An update].

Ann Pathol 2016 Jan 7;36(1):55-62. Epub 2016 Jan 7.

Service d'anatomie pathologique, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; Inserm U 970, équipe 10, faculté Paris Descartes, PARCC, 56, rue Leblanc, 75015 Paris, France. Electronic address:

"Salivary gland-type" tumors arising from the bronchi and lung are rare but not exceptional entities. They are mostly represented by malignant entities such as cystic adenoid carcinoma, mucoepidermoid carcinoma and epithelial/myoepithelial carcinoma. Benign tumors are rare, mainly encompassing pleomorphic adenomas, which are to differentiate from mucous gland adenomas, another entity arising specifically from the peri-bronchial glands. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02426498150022
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http://dx.doi.org/10.1016/j.annpat.2015.11.003DOI Listing
January 2016
33 Reads

The value of SHOX2 methylation test in peripheral blood samples used for the differential diagnosis of lung cancer and other lung disorders.

Neoplasma 2016 ;63(2):246-53

Methylation of the cytosine residues within the CpG dinucleotides plays an important role in the fundamental cellular processes, human diseases and even cancer. The DNA methylation represents a very stable sign and therefore may be used as a valuable marker for cancer screening. Epigenetic cancer biomarkers are independent of classical morphology and thus show extensive potential to overcome the limitations of cytology. Read More

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http://www.elis.sk/index.php?page=shop.product_details&f
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http://dx.doi.org/10.4149/210_150419N208DOI Listing
January 2019
9 Reads

Non-cardiovascular findings in clinical cardiovascular magnetic resonance imaging in children.

Pediatr Radiol 2016 Apr 11;46(4):473-82. Epub 2016 Jan 11.

Department of Radiology, Division of Cardiothoracic Radiology, University of Michigan Health System, Ann Arbor, MI, USA.

Background: With increasing use of pediatric cardiovascular MRI, it is important for all imagers to become familiar with the spectrum of non-cardiovascular imaging findings that can be encountered.

Objective: This study aims to ascertain the prevalence and nature of these findings in pediatric cardiovascular MRIs performed at our institution.

Materials And Methods: We retrospectively evaluated reports of all cardiovascular MRI studies performed at our institute from January 2008 to October 2012 in patients younger than18 years. Read More

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http://link.springer.com/10.1007/s00247-015-3512-8
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http://dx.doi.org/10.1007/s00247-015-3512-8DOI Listing
April 2016
17 Reads
1.651 Impact Factor

Palliative Cryotherapy of Aggressive Endobronchial Parotid Carcinoma ex Pleomorphic Adenoma: A Case Report.

Mil Med 2015 Dec;180(12):e1281-3

Naval Medical Center San Diego, Pulmonary Medicine Building 3-3, 34730 Bob Wilson Drive, San Diego, CA 92134.

Carcinoma ex pleomorphic adenoma is a rare salivary gland malignancy with a poor prognosis that can metastasize to the lungs. Endobronchial metastasis and associated bronchoscopic characteristics have not been described in the literature. Cryotherapy is a safe and efficacious palliative treatment option for obstructive bronchial tumors that can be performed with flexible bronchoscopy. Read More

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http://dx.doi.org/10.7205/MILMED-D-14-00705DOI Listing
December 2015
30 Reads

An immunohistochemical comparison of two TTF-1 monoclonal antibodies in atypical squamous lesions and sarcomatoid carcinoma of the lung, and pleural malignant mesothelioma.

J Clin Pathol 2016 Feb 17;69(2):136-41. Epub 2015 Aug 17.

Department of Surgical Pathology, SA Pathology at Flinders Medical Centre, Adelaide, South Australia, Australia.

Unlabelled: Immunohistochemical detection of thyroid transcription factor-1 (TTF-1) plays an important role in the diagnosis and subclassification of non-small cell carcinomas of the lung in biopsy and some cytology samples, specifically for identification of squamous cell carcinoma (classically negative) and non-mucinous adenocarcinoma (positive in most cases) and for discrimination between lung adenocarcinoma and pleural malignant mesothelioma (classically negative).

Aims And Methods: We carried out a comparison of the widely used mouse monoclonal TTF-1 antibody based on the 8G7G3/1 clone versus the more recently introduced rabbit monoclonal antibody (MAb) based on the SP141 clone.

Results: Both antibodies labelled alveolar epithelium in normal lung parenchyma, but the SP141 antibody also labelled bronchial mucosal basal cells. Read More

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http://dx.doi.org/10.1136/jclinpath-2015-203184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752635PMC
February 2016
53 Reads

18F-FDG PET/CT of Bronchial Mucous Gland Adenoma.

Clin Nucl Med 2016 Feb;41(2):e118-9

From the *Department of Nuclear Medicine, Korea University Anam Hospital; †Department of Nuclear Medicine, Korea University Guro Hospital; ‡Division of Pulmonology, Department of Internal Medicine, and §Department of Pathology, Korea University Anam Hospital, Seoul, Republic of Korea.

Bronchial mucous gland adenoma is a very rare benign tumor that arises from the bronchial mucous-secreting glands. Its detection and appearance using F-FDG PET/CT has not been well characterized. We present a case of a 59-year-old man with FDG-avid mucous gland adenoma that mimicked lung cancer on F-FDG PET/CT. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/RLU.0000000000000921DOI Listing
February 2016
16 Reads

Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model.

Cancer Sci 2015 Oct 19;106(10):1296-302. Epub 2015 Sep 19.

Department of Hematology, Oncology and Respiratory Medicine, Okayama University Hospital, Okayama, Japan.

Malignant mesothelioma is an aggressive and therapy-resistant neoplasm arising from mesothelial cells. Evidence suggests that the major pathology associated with asbestos-induced mesothelioma is local iron overload. In the present study, we induced iron-induced mesothelioma in rats based on previous reports. Read More

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http://doi.wiley.com/10.1111/cas.12752
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http://dx.doi.org/10.1111/cas.12752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638004PMC
October 2015
22 Reads

Endocytosis of Multiwalled Carbon Nanotubes in Bronchial Epithelial and Mesothelial Cells.

Biomed Res Int 2015 18;2015:793186. Epub 2015 May 18.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

Bronchial epithelial cells and mesothelial cells are crucial targets for the safety assessment of inhalation of carbon nanotubes (CNTs), which resemble asbestos particles in shape. Intrinsic properties of multiwalled CNTs (MWCNTs) are known to cause potentially hazardous effects on intracellular and extracellular pathways. These interactions alter cellular signaling and affect major cell functions, resulting in cell death, lysosome injury, reactive oxygen species production, apoptosis, and cytokine release. Read More

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http://dx.doi.org/10.1155/2015/793186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450259PMC
March 2016
16 Reads

Amplatzer Device in Bronchial Stump Fistula after Extrapleural Pneumonectomy.

Thorac Cardiovasc Surg 2016 Sep 18;64(6):540-2. Epub 2015 May 18.

Department of General Thoracic and Esophageal Surgery, Helsinki University Central Hospital, Heart and Lung Center, Helsinki, Finland.

Endoscopically superimposed Amplatzer (St. Jude Medical, St. Paul, Minnesota, United States) septal occluder plug was successfully used in the treatment of septic right main bronchus fistula having developed after extrapleural pneumonectomy and heated chemotherapy in two patients with malignant pleural mesothelioma. Read More

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http://dx.doi.org/10.1055/s-0035-1549358DOI Listing
September 2016
49 Reads

Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor formation by miR-16.

Oncotarget 2015 Apr;6(12):10222-38

Department of Life Sciences and Agricultural Biotechnology Center, National Chung Hsing University, Taichung 402, Taiwan.

Many studies have shown that vascular endothelial growth factor (VEGF), especially the human VEGF-A165 (hVEGF-A165) isoform, is a key proangiogenic factor that is overexpressed in lung cancer. We generated transgenic mice that overexpresses hVEGF-A165 in lung-specific Clara cells to investigate the development of pulmonary adenocarcinoma. In this study, three transgenic mouse strains were produced by pronuclear microinjection, and Southern blot analysis indicated similar patterns of the foreign gene within the genomes of the transgenic founder mice and their offspring. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496351PMC
http://dx.doi.org/10.18632/oncotarget.3390DOI Listing
April 2015
37 Reads

[Current situation and perspectives of proton therapy].

Cancer Radiother 2015 May 1;19(3):211-9; quiz 231-2, 235. Epub 2015 Apr 1.

Pôle de radiothérapie, centre Antoine-Lacassagne, université Nice-Sophia, 33, avenue de Valombrose, 06000 Nice, France. Electronic address:

Proton beam therapy is indicated as a treatment for some rare tumours and paediatric tumours because the technique allows a good local control with minimal toxicity; the growing number of centres that use proton beam therapy is associated with an increase of dosimetric and clinical data for other malignant tumours as well. This paper reviews potential indications of proton beam therapy. A systematic review on Medline was performed with the following keywords proton beam therapy, cancer, heavy particle, charged particle. Read More

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http://dx.doi.org/10.1016/j.canrad.2014.12.010DOI Listing
May 2015
13 Reads

Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs.

J Nucl Med 2015 Apr 19;56(4):613-5. Epub 2015 Feb 19.

Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland.

Unlabelled: A high proportion of gut and bronchial neuroendocrine tumors (NETs) overexpresses somatostatin receptors, especially the sst2 subtype. It has also recently been observed that incretin receptors, namely glucagonlike peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptors, can be overexpressed in gut and bronchial NETs. However, because not all tumors can express these receptors in sufficient amounts, in vivo imaging with a single radioligand may not always be successful. Read More

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http://jnm.snmjournals.org/content/56/4/613.full.pdf
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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.114.153189
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http://dx.doi.org/10.2967/jnumed.114.153189DOI Listing
April 2015
15 Reads

Asbestos-related occupational cancers compensated under the Spanish National Insurance System, 1978-2011.

Int J Occup Environ Health 2015 21;21(1):31-9. Epub 2014 Oct 21.

Background: In 1978, asbestos-related occupational cancers were added to the Spanish list of occupational diseases. However, there are no full accounts of compensated cases since their inclusion.

Objective: To analyze the cases of asbestos-related cancer recognized as occupational in Spain between 1978 and 2011. Read More

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http://dx.doi.org/10.1179/2049396714Y.0000000087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273517PMC
August 2016
13 Reads

Digital quantification of air leak to identify the location of an alveolopleural fistula.

Ann Am Thorac Soc 2014 Sep;11(7):1152-4

Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1513/AnnalsATS.201404-176CCDOI Listing
September 2014
15 Reads

Fetal bronchoscopy as a useful procedure in a case with prenatal diagnosis of congenital microcystic adenomatoid malformation.

Fetal Diagn Ther 2015 14;37(1):75-80. Epub 2014 Aug 14.

Massive microcystic congenital cystic adenomatoid malformation (CCAM) and bronchial atresia are associated with a high perinatal mortality secondary to lung hypoplasia and cardiac dysfunction, and fetal intervention should be considered to improve prognosis. Therapeutic options include open fetal surgery with pulmonary resection, fetal sclerotherapy and fetoscopy. We present a case with a severely enlarged left lung without ultrasound signs of dilated airways compatible with the diagnosis of microcystic CCAM, hydrops and severe contralateral lung hypoplasia that was treated successfully at 30 weeks of gestation by fetal bronchoscopy, through which bronchial atresia was identified at the end of the left mainstem bronchi and permeabilized by laser ablation. Read More

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https://www.karger.com/Article/FullText/361015
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http://dx.doi.org/10.1159/000361015DOI Listing
November 2015
16 Reads

[Small intestinal perforation due to metastasis from pulmonary pleomorphic carcinoma; report of a case].

Kyobu Geka 2014 Aug;67(9):856-9

Department of Thoracic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.

A 63-year-old male patient was referred to our department for an abnormal shadow in the left middle lung field. The patient underwent trans bronchial lung biopsy and pathological finding was adenocarcinoma. Computed tomography( CT) showed mass in the left lower lobe, nodules in the bilateral adrenal glands, liver, pancreas and lumbar bone. Read More

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August 2014
18 Reads

Bronchial mucous gland adenoma presenting as massive hemoptysis: A diagnostic dilemma.

Lung India 2014 Jul;31(3):274-6

Department of Cardiothoracic and Vascular Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab and Haryana, India.

Mucous gland adenoma of the lung is an uncommon benign tumor that histologically resembles the mucus-secreting component of tracheobronchial gland. The majority arises within the main, lobar, or segmental bronchi but parenchymal involvement had also been reported. We herein present a case of mucous gland adenoma arising from the left lower lobe bronchus. Read More

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http://dx.doi.org/10.4103/0970-2113.135776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129603PMC
July 2014
29 Reads

A historical appreciation of bronchopulmonary neuroendocrine neoplasia: resolution of a carcinoid conundrum.

Thorac Surg Clin 2014 Aug;24(3):235-55

Department of Surgery, Yale School of Medicine, 310 Cedar Street, New Haven, CT 06520, USA.

In the three-quarters of a century that have elapsed since the first description of a bronchial carcinoid, the field has progressed from serendipitous radiological or bronchoscopic diagnosis to computed tomography, magnetic resonance imaging, and somatostatin receptor imaging identification. Similarly, pathologic techniques have advanced from a naïve assessment of neoplasia to a delineation of several tumor subtypes and an understanding of the neuroendocrine basis of the disease process. A key unresolved question is the identification of the genetic and environmental activators that are responsible for the initiation of pulmonary neuroendocrine cell proliferation and neoplastic transformation. Read More

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http://dx.doi.org/10.1016/j.thorsurg.2014.05.008DOI Listing
August 2014
19 Reads

[A very rare cause of haemoptysis - coexistence of primary oncocytic adenoma of trachea with bronchial carcinoma].

Dtsch Med Wochenschr 2014 Jun 3;139(24):1295-8. Epub 2014 Jun 3.

Medizinische Klinik für Pneumologie, Kardiologie und Allergologie, Malteserkrankenhaus Bonn.

History And Admission Findings: A 70-year-old man with a past history of COPD stage GOLD D with home oxygen therapy and tracheotomy due to long-term ventilation (898 hours) 6 years ago was admitted for investigation of haemoptysis during oral anticoagulation. He suffered from peripheral arterial disease (PAD) with bypass and repeated thrombectomy due to recurrent bypass caps, despite effective warfarin therapy. He had all cardiovascular risk factors. Read More

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http://dx.doi.org/10.1055/s-0034-1370103DOI Listing
June 2014
17 Reads

[Cushing syndrome: Physiopathology, etiology and principles of therapy].

Authors:
Olivier Chabre

Presse Med 2014 Apr 20;43(4 Pt 1):376-92. Epub 2014 Mar 20.

CHU de Grenoble, Hôpital Nord, Service d'Endocrinologie-Diabétologie-Nutrition, BP 217, 38043 Grenoble cedex 9, France; Faculté de Médecine, Université Joseph Fourier, Grenoble-1, 38042 Grenoble cedex 9, France. Electronic address:

The most frequent cause of Cushing's syndrome is iatrogenic, as Cushing's syndrome is the unavoidable consequence of long-term glucocorticoid treatment using more than 7.5 mg prednisone per day. The most frequent cause of endogenous Cushing's syndrome is Cushing's disease (CD), which is an ACTH dependent hypercortisolism linked to a pituitary corticotroph adenoma. Read More

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http://dx.doi.org/10.1016/j.lpm.2014.02.001DOI Listing
April 2014
14 Reads

Management of endocrine disease: a clinical update on tumor-induced hypoglycemia.

Eur J Endocrinol 2014 Apr 14;170(4):R147-57. Epub 2014 Mar 14.

Department of Endocrinology, Hospital Ramón y Cajal, Ctra. de Colmenar, Km 9.100, 28034 Madrid, Spain.

Tumor-induced hypoglycemia (TIH) is a rare clinical entity that may occur in patients with diverse kinds of tumor lineages and that may be caused by different mechanisms. These pathogenic mechanisms include the eutopic insulin secretion by a pancreatic islet β-cell tumor, and also the ectopic tumor insulin secretion by non-islet-cell tumor, such as bronchial carcinoids and gastrointestinal stromal tumors. Insulinoma is, by far, the most common tumor associated with clinical and biochemical hypoglycemia. Read More

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http://dx.doi.org/10.1530/EJE-13-1012DOI Listing
April 2014
16 Reads

[Sialadenoma papilliferum--a rare benign endobronchial tumor].

Dtsch Med Wochenschr 2014 Jan 21;139(5):187-90. Epub 2014 Jan 21.

Klinik für Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin und thorakale Onkologie, Lungenklinik Lostau.

Unlabelled: HISTORY AND PRESENTATION AT ADMISSION: An 82-year-old male patient presented with a 3 week history of exercise-induced dyspnea, productive cough and left sided chest pain.

Investigations: Computertomography of the chest revealed an occluding endobronchial tumor in the left main bronchus with enlarged mediastinal lymph nodes, mediastinal shift and post-stenotic peribronchitis.

Treatment And Course: The tumor was removed completely with an optical forceps in rigid bronchoscopy. Read More

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http://dx.doi.org/10.1055/s-0033-1359983DOI Listing
January 2014
19 Reads