23,560 results match your criteria Acute Rheumatic Fever


Haemophagocytic syndrome in Systemic Lupus Erythematosus - clues to an early diagnosis.

Acta Reumatol Port 2018 Oct-Dec;43(4):318-320

Centro Hospitalar São João.

Macrophage activation syndrome (MAS) is a rare life-threatening condition that involves excessive activation of inflammatory cells and overproduction of different cytokines. It is characterized by persistent fever, hepatosplenomegaly, cytopenias and coagulopathy. Other prominent features are hyperferritinemia and findings of activated macrophages in haemopoietic organs, often associated with multi-organ impairment. Read More

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January 2019

Myocardial calcification secondary to toxic shock syndrome: a comparative review of 17 cases.

BMJ Case Rep 2019 Jan 10;12(1). Epub 2019 Jan 10.

Cleveland Clinic - Fairview Hospital, Cleveland, Ohio, USA.

Myocardial calcification is a rare and life-threatening condition. It has been associated with a myriad of causes, including ischaemic heart disease, cardiac surgery, rheumatic fever, and myocarditis. However, this entity is less well recognised in the setting of toxic shock syndrome. Read More

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http://dx.doi.org/10.1136/bcr-2018-228054DOI Listing
January 2019
1 Read

Early onset, non-rheumatic, group A streptococcal-associated myocarditis.

Clin Exp Rheumatol 2019 Jan 3. Epub 2019 Jan 3.

Rheumatology Research Center, Department of Medicine, and Department of Medicine B, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Objectives: Group A streptococcal (GAS) tonsillitis is reported as an uncommon cause of acute non-rheumatic fever (non-RF) myocarditis. The aim of this research was to study the occurrence, diagnosis, management and prognosis of this condition.

Methods: We conducted a retrospective computerised search through medical records of patients admitted to our tertiary medical center between 1998-2016 with the diagnosis of either acute rheumatic fever or non-RF streptococcal myocarditis based on criteria we developed and review the relevant literature from 1973-2016. Read More

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January 2019
2.724 Impact Factor

Sickening or Healing the Heart? The Association of Ficolin-1 and Rheumatic Fever.

Front Immunol 2018 18;9:3009. Epub 2018 Dec 18.

Molecular Immunopathology Laboratory, Department of Medical Pathology, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil.

Rheumatic fever (RF) and its subsequent progression to rheumatic heart disease (RHD) are chronic inflammatory disorders prevalent in children and adolescents in underdeveloped countries, and a contributing factor for high morbidity and mortality rates worldwide. Their primary cause is oropharynx infection by , whose acetylated residues are recognized by ficolin-1. This is the only membrane-bound, as well as soluble activator molecule of the complement lectin pathway (LP). Read More

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http://dx.doi.org/10.3389/fimmu.2018.03009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305461PMC
December 2018
1 Read

Pediatric rheumatology in Turkey.

Rheumatol Int 2019 Jan 3. Epub 2019 Jan 3.

Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Pediatric Rheumatology is an emerging specialty in Turkey with increasing number of available centers and specialists all over the country. In this paper, we sought to provide an overview on pediatric rheumatology service in our country, as well as to assess the principle published literature from Turkey in this field. A systematic literature search has been performed to achieve the significance and the impact of this manuscript. Read More

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http://dx.doi.org/10.1007/s00296-018-04236-xDOI Listing
January 2019
2 Reads

School-based surveillance for detection of children with acute pharyngitis, rheumatic fever/rheumatic heart disease in Shimla district, Himachal Pradesh, India-A cluster randomized controlled trial.

Indian Heart J 2018 Dec 30;70 Suppl 3:S74-S81. Epub 2018 May 30.

CUNY School of Public Health University, New York, USA.

Background: The lack of surveillance system is a major barrier in prevention and control of rheumatic fever/rheumatic heart disease (RF/RHD). Efficacy of school-based surveillance was evaluated for detection of acute pharyngitis and RF/RHD in Shimla district, HP.

Methods: The schools in district Shimla were randomly assigned to intervention and controlled arm (442 vs. Read More

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http://dx.doi.org/10.1016/j.ihj.2018.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309137PMC
December 2018
1 Read

Prevalence, risk determinants and consequences of atrial fibrillation in rheumatic heart disease: 6 years hospital based-Himachal Pradesh- Rheumatic Fever/Rheumatic Heart Disease (HP-RF/RHD) Registry.

Indian Heart J 2018 Dec 19;70 Suppl 3:S68-S73. Epub 2018 May 19.

IGMC, Shimla, HP, India.

Objective: To report the prevalence, risk factors and consequences of atrial fibrillation (AF) in patients of rheumatic heart disease (RHD).

Methods: The Himachal Pradesh- Rheumatic Fever/Rheumatic Heart Disease (HP-RF/RHD) Registry database of 1918 patients was analyzed. AF was diagnosed with 12-lead ECG recording at entry in to the registry. Read More

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http://dx.doi.org/10.1016/j.ihj.2018.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309149PMC
December 2018
1 Read

Secondary prophylaxis to control rheumatic heart disease in developing countries: Put into a cage if can't be killed.

Indian Heart J 2018 Nov - Dec;70(6):907-910. Epub 2018 Jan 8.

All India Institute of Medical Sciences, Bhubaneswar, India. Electronic address:

A significant socioeconomic inequality is the main barrier to achieve primordial prevention of rheumatic heart disease (RHD) in the developing countries. An effective vaccine with affordable cost against Streptococcus yet to be identified. The subclinical nature of rheumatic fever (RF) is the main hurdle for effective primary prevention of RHD. Read More

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http://dx.doi.org/10.1016/j.ihj.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306397PMC
January 2019
1 Read

Is Inflammasome a Potential Target of Prophylaxis in Rheumatic Heart Disease?

Circulation 2018 Dec;138(23):2662-2665

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317860PMC
December 2018
3 Reads

Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine.

Circulation 2018 Dec;138(23):2648-2661

Divisions of Inflammation (M.L.K., W.J.M., J.L.K., I.P.W.), Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Background: Acute rheumatic fever (ARF) and rheumatic heart disease are autoimmune consequences of group A streptococcus infection and remain major causes of cardiovascular morbidity and mortality around the world. Improved treatment has been stymied by gaps in understanding key steps in the immunopathogenesis of ARF and rheumatic heart disease. This study aimed to identify (1) effector T cell cytokine(s) that might be dysregulated in the autoimmune response of patients with ARF by group A streptococcus, and (2) an immunomodulatory agent that suppresses this response and could be clinically translatable to high-risk patients with ARF. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033891DOI Listing
December 2018
3 Reads

How Many Doses Make a Difference? An Analysis of Secondary Prevention of Rheumatic Fever and Rheumatic Heart Disease.

J Am Heart Assoc 2018 Dec;7(24):e010223

1 Menzies School of Health Research Charles Darwin University Darwin Australia.

Background Acute rheumatic fever ( ARF ) and rheumatic heart disease cause substantial burdens worldwide. Long-term antibiotic secondary prophylaxis is used to prevent disease progression, but evidence for benefits of different adherence levels is limited. Using data from northern Australia, we identified factors associated with adherence, and the association between adherence and ARF recurrence, progression to rheumatic heart disease, worsening or improvement of rheumatic heart disease, and mortality. Read More

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http://dx.doi.org/10.1161/JAHA.118.010223DOI Listing
December 2018
1 Read

Involvement of inflammatory responses in the early development of calcific aortic valve disease: lessons from statin therapy.

Anim Cells Syst (Seoul) 2018 28;22(6):390-399. Epub 2018 Sep 28.

Department of Life Science, College of Natural Sciences, Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.

Calcific aortic valve disease (CAVD) is the most common degenerative heart valve disease. Among the many risk factors for this disease are age, hypercholesterolemia, hypertension, smoking, type-2 diabetes, rheumatic fever, and chronic kidney disease. Since many of these overlap with risk factors for atherosclerosis, the molecular and cellular mechanisms of CAVD development have been presumed to be similar to those for atherogenesis. Read More

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http://dx.doi.org/10.1080/19768354.2018.1528175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282465PMC
September 2018
1 Read

A Rare Case of Macrophage Activation Syndrome Presenting as the First Manifestation of Systemic Lupus Erythematosus.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618812196. Epub 2018 Nov 15.

State University of New York Upstate Medical University, Syracuse, NY, USA.

Macrophage activation syndrome (MAS) itself is a rare, potentially life-threatening complication of a rheumatic disease, mostly seen in juvenile idiopathic arthritis. It infrequently occurs in systemic lupus erythematosus (SLE), and it is extremely rare to be the first presentation of SLE. In a study of 511 patients with SLE, 7 cases (1. Read More

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http://dx.doi.org/10.1177/2324709618812196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243398PMC
November 2018
1 Read

Syncope due to complete atrioventricular block and treatment with a transient pacemaker in acute rheumatic fever.

Turk Pediatri Ars 2018 Sep 1;53(3):197-199. Epub 2018 Sep 1.

Department of Pediatric Cardiology, Necip Fazıl City Hospital, Kahramanmaraş, Turkey.

Various rhythm and connection disorders can be seen in the acute phase of acute rheumatic fever. First degree atrioventricular block, one of the minor signs of acute rheumatic fever, is the most common connection disturbance in this disease. Complete atrioventricular block, which seriously affects the conduction pathways, is rare in the literature. Read More

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http://dx.doi.org/10.5152/TurkPediatriArs.2018.4014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239074PMC
September 2018
1 Read

Plantago squarrosa Murray extracts inhibit the growth of some bacterial triggers of autoimmune diseases: GC-MS analysis of an inhibitory extract.

Inflammopharmacology 2018 Nov 16. Epub 2018 Nov 16.

School of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, QLD, 4111, Australia.

Ankylosing spondylitis, multiple sclerosis, rheumatoid arthritis and rheumatic fever are autoimmune inflammatory diseases that may be triggered in genetically susceptible individuals by specific bacterial pathogens. Inhibiting the growth of these bacteria with high antioxidant plant extracts may inhibit the aetiology of these diseases, as well as inhibiting the later phase symptoms. P. Read More

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http://link.springer.com/10.1007/s10787-018-0547-0
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http://dx.doi.org/10.1007/s10787-018-0547-0DOI Listing
November 2018
10 Reads

Extracting Thickness Profiles of Anterior Mitral Leaflets in Echocardiography Videos.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:3582-3585

Rheumatic heart disease is the serious consequence of repeated episodes of acute rheumatic fever. It is the major cause of heart valve damage resulting in morbidity and mortality. Its early detection is considered vital to control the disease's progression. Read More

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https://ieeexplore.ieee.org/document/8512963/
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http://dx.doi.org/10.1109/EMBC.2018.8512963DOI Listing
July 2018
8 Reads

A New Method for the Anterior Mitral Leaflet Segmentation in Echocardiography Videos using the Virtual M-mode Space.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:3120-3123

Rheumatic heart disease is responsible for the heart valve damage, caused by repeated episodes of rheumatic fever. The disease commonly inflames and scars the mitral valve of the heart, resulting in thicker, less mobile leaflets, with associated decrease in cardiac efficiency. It is important to measure and quantity the early manifestations of this disease, including variations of the thickness, shape and mobility of the leaflets. Read More

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https://ieeexplore.ieee.org/document/8512913/
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http://dx.doi.org/10.1109/EMBC.2018.8512913DOI Listing
July 2018
5 Reads

Native valve dual pathogen endocarditis caused by and - a case report.

JMM Case Rep 2018 Sep 8;5(9):e005143. Epub 2018 Mar 8.

Armed Forces Institute of Pathology, National University of Medical Sciences, Islamabad, Pakistan.

Introduction: Infective endocarditis (IE) is an important clinical condition with significant morbidity and mortality among the affected population. A single etiological agent is identifiable in more than 90 % of the cases, however, polymicrobial endocarditis (PE) is a rare find, with a poor clinical outcome. Here we report a case of native valve dual pathogen endocarditis caused by and in an immunocompetent individual. Read More

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http://www.microbiologyresearch.org/content/journal/jmmcr/10
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http://dx.doi.org/10.1099/jmmcr.0.005143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230757PMC
September 2018
11 Reads

Group A disease in Hong Kong children: an overview.

Hong Kong Med J 2018 Nov 9. Epub 2018 Nov 9.

Department of Paediatrics, Alberta Children's Hospital, The University of Calgary, Calgary, Alberta, Canada.

Group A β-haemolytic or is a gram-positive coccus that tends to grow in chains. is the cause of many important human diseases, ranging from pharyngitis and mild superficial skin infections to life-threatening systemic diseases. Infections typically begin in the throat or skin. Read More

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http://dx.doi.org/10.12809/hkmj187275DOI Listing
November 2018
3 Reads

Poor long-term adherence to secondary penicillin prophylaxis in children with history of rheumatic fever.

Semin Arthritis Rheum 2018 Oct 16. Epub 2018 Oct 16.

Pediatric Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikva 4920235, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Objective: Recurrent episodes of acute rheumatic fever may contribute to the development or worsening of rheumatic heart disease. Secondary penicillin prophylaxis (SPP) has been found to significantly reduce the incidence of rheumatic heart disease. This study sought to evaluate adherence to oral and intramuscular SPP in pediatric patients with rheumatic fever using real-world data spanning 10 years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183042
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http://dx.doi.org/10.1016/j.semarthrit.2018.10.015DOI Listing
October 2018
4 Reads

Tuberculous coxitis with trochanteric bursitis manifesting a year after immigration to Germany: a case report.

J Med Case Rep 2018 Nov 7;12(1):332. Epub 2018 Nov 7.

Hannover Medical University, Clinic for Immunology and Rheumatology, Carl-Neubergstr. 1, 30625, Hannover, Germany.

Background: Osteoarticular tuberculosis is rare in Germany. In particular, trochanteric bursitis is an extremely rare manifestation of osteoarticular tuberculosis. We describe a case of tuberculous coxitis with trochanteric bursitis, successfully treated with a fourfold tuberculostatic therapy. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1867-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220512PMC
November 2018
11 Reads

Comparative study on maternal and fetal outcome in pregnant women with rheumatic heart disease and severe mitral stenosis undergoing percutaneous balloon mitral valvotomy before or during pregnancy.

Indian Heart J 2018 Sep - Oct;70(5):685-689. Epub 2018 Jan 9.

Department of Obstetrics and Gynecology, AIIMS, New Delhi, India.

Introduction: Mitral stenosis due to rheumatic heart disease is a common problem in India causing significant morbidity and mortality. We have compared the maternal and fetal outcome of women with severe mitral stenosis undergoing percutaneous balloon mitral valvotomy before or during pregnancy.

Methods: A total of 24 women of severe rheumatic mitral stenosis who underwent balloon mitral valvotomy before pregnancy (14 women, group 1) or during pregnancy (10 women, group 2) were included in the retrospective descriptive analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00194832173035
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http://dx.doi.org/10.1016/j.ihj.2018.01.018DOI Listing
January 2019
3 Reads

Management of Pharyngitis.

Authors:
Jonathan Berkley

Circulation 2018 Oct;138(18):1920-1922

Kupat Holim Meuhedet, Jerusalem District, Israel.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035900DOI Listing
October 2018
8 Reads

Chagas Cardiomyopathy: An Update of Current Clinical Knowledge and Management: A Scientific Statement From the American Heart Association.

Circulation 2018 Sep;138(12):e169-e209

Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally regarded as a tropical disease found only in Central America and South America, Chagas disease now affects at least 300 000 residents of the United States and is growing in prevalence in other traditionally nonendemic areas. Healthcare providers and health systems outside of Latin America need to be equipped to recognize, diagnose, and treat Chagas disease and to prevent further disease transmission. Read More

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http://dx.doi.org/10.1161/CIR.0000000000000599DOI Listing
September 2018
3 Reads

Complete heart block in young adult with acute rheumatic fever.

Med J Malaysia 2018 Oct;73(5):323-325

Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan, Malaysia.

Acute Rheumatic fever (ARF) is commonly associated with ECG abnormalities particularly atrioventricular block. However, third degree atrioventricular block or complete heart block is a rare manifestation. Most cases occurred in children. Read More

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October 2018
8 Reads

The leaves of Crataeva nurvala Buch-Ham. modulate locomotor and anxiety behaviors possibly through GABAergic system.

BMC Complement Altern Med 2018 Oct 19;18(1):283. Epub 2018 Oct 19.

Designated Reference Institute for Chemical Measurement (DRiCM), Bangladesh Council of Scientific & Industrial Research, Dhaka, 1205, Bangladesh.

Background: Crataeva nurvala Buch-Hum is an indigenous herb, extensively used in traditional medicines of the South Asian countries to treat inflammation, rheumatic fever, gastric irritation, and constipation. Despite this wide range of uses, very little information is known regarding its effects on the central nervous system (CNS). Therefore, this study evaluated the neuropharmacological properties of methanolic extract of Crataeva nurvala leaves (MECN) using a number of behavioral models in animals. Read More

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https://bmccomplementalternmed.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12906-018-2338-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194725PMC
October 2018
4 Reads
2.020 Impact Factor

Noncaseating suppurative granulomatous lymphadenitis in adult onset Still's disease - a diagnostic dilemma in a tuberculosis-endemic region: a case report.

J Med Case Rep 2018 Oct 15;12(1):299. Epub 2018 Oct 15.

Sri Jayewardenepura General Hospital and Post-graduate Training Institute, Sri Jayawardenepura Kotte, Western Province, Sri Lanka.

Background: Lymphadenopathy is not an uncommon presentation of adult onset Still's disease: it is present in up to two thirds of patients with adult onset Still's disease. The characteristic appearance of lymphadenopathy is described as intense, paracortical immunoblastic hyperplasia. Changes in light microscopy may resemble lymphoma, but immunohistochemistry reveals a benign polyclonal B cell hyperplasia. Read More

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http://dx.doi.org/10.1186/s13256-018-1816-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192002PMC
October 2018
2 Reads

The medicinal uses, toxicities and anti-inflammatory activity of Polyalthia species (Annonaceae).

J Ethnopharmacol 2019 Jan 11;229:303-325. Epub 2018 Oct 11.

Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Ethnopharmacological Relevance: Polyalthia is one of the largest and notable genera in Annonaceae family. Polyalthia species have been widely used in folklore medicine for the treatment of rheumatic fever, gastrointestinal ulcer and generalized body pain. Numerous in vitro and in vivo studies on Polyalthia Species have also corroborated the significant anti-inflammatory potential of its extracts and secondary metabolites. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183175
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http://dx.doi.org/10.1016/j.jep.2018.10.001DOI Listing
January 2019
8 Reads

Early and Midterm Outcomes of Rheumatic Mitral Valve Repair.

Heart Surg Forum 2018 Aug 14;21(5):E352-E358. Epub 2018 Aug 14.

Department of Cardiac Surgery, National Heart Institute, Cairo, Egypt.

Background: Rheumatic heart disease (RHD) is the leading cause of mitral valve disease in the developing world. In general, mitral valve repair is preferred over replacement. Although it is very successful in degenerative disease, its results in the rheumatic valve are not as successful as that for degenerative repair. Read More

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http://dx.doi.org/10.1532/hsf.1978DOI Listing
August 2018
3 Reads
0.562 Impact Factor

Fish mouth appearance: Mitral valve.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:28

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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http://doi.wiley.com/10.1111/1754-9485.15_12785
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http://dx.doi.org/10.1111/1754-9485.15_12785DOI Listing
October 2018
2 Reads

The role of cardiovascular magnetic resonance imaging in rheumatic heart disease.

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):171-176. Epub 2018 Oct 1.

Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany.

Cardiovascular involvement is a well-known feature of inflammatory rheumatic diseases, although often clinically silent, so early cardiovascular involvement may remain unrecognised. Thus, increased awareness and improved insights into the pathomechanisms of heart disease in the context of inflammatory rheumatic disease has led to an emerging role of cardiovascular magnetic resonance (CMR) as an accurate and non-invasive diagnostic test for detection of early (as well as late) cardiovascular involvement in inflammatory rheumatic disease. The present article will review the current potential as well as the limitations of established and emerging, qualitative and quantitative CMR techniques in the setting of inflammatory rheumatic disease and shed some light onto current developments in the field. Read More

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January 2019
1 Read

An old disease re-emerging: acute rheumatic fever.

Clin Med (Lond) 2018 Oct;18(5):400-402

Barts Health NHS Foundation Trust, London, UK.

We present the case of a 41-year-old Australian woman with a 3-day history of fevers and migratory polyarthritis. Three weeks prior she had been treated by her GP with phenoxymethylpenicillin for acute tonsillitis. Examination confirmed synovitis. Read More

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http://dx.doi.org/10.7861/clinmedicine.18-5-400DOI Listing
October 2018
1 Read
1.685 Impact Factor

Reoperation for isolated rheumatic tricuspid regurgitation.

J Cardiothorac Surg 2018 Oct 4;13(1):104. Epub 2018 Oct 4.

Cardiac surgery department, Mohammed V teaching military hospital, Hay Riyad, PB 10100, Rabat, Morocco.

Background: The reoperation for isolated tricuspid regurgitation in rheumatic population is rare and still unclear and controversial because of the rarity of publications. The aim of this study was to analyze short and long-term results and outcome of tricuspid valve surgery after left-sided valve surgery in rheumatic patients.

Methods: Twenty six consecutive rheumatic patients who underwent isolated tricuspid valve surgery after left-sided valve surgery between January 2000 and January2017 were retrospectively registered in the study. Read More

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https://cardiothoracicsurgery.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s13019-018-0793-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172749PMC
October 2018
2 Reads

Is population-based screening for rheumatic heart disease precluded by the Cairo accord? Echocardiography...and beyond.

Congenit Heart Dis 2018 Nov 2;13(6):1069-1071. Epub 2018 Oct 2.

Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.

In the 2017, "Cairo Accord on Rheumatic Heart Disease-From Molecules to The Global Community" experts from endemic areas enumerated an approach to reduce the population burden of rheumatic heart disease. The 10 key recommendations include immediate logistical objectives as well as domains for further study. Echocardiographic population screening programs were relegated to research alone. Read More

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http://dx.doi.org/10.1111/chd.12676DOI Listing
November 2018

Fourth mitral valve replacement in a 15-year span in a woman of childbearing age.

J Cardiol Cases 2018 Sep 13;18(3):110-112. Epub 2018 Jun 13.

Cardiology Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.

There is no report of four valve replacement surgeries in a woman during 15-year follow-up. A 23-year-old female was diagnosed at 7 years with rheumatic fever. She developed severe mitral regurgitation and at the same age a prosthetic valve was placed. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149623PMC
September 2018
18 Reads

Concurrent diagnosis of infective endocarditis and acute rheumatic fever: A case report.

J Cardiol Cases 2018 May 7;17(5):147-150. Epub 2018 Feb 7.

Department of Pathology, Iran University of Medical Sciences, Tehran, Iran.

Rheumatic heart disease has been classically considered as a risk factor for infective endocarditis (IE). Although valvulitis is frequently present in patients with acute rheumatic fever (ARF), the established valve disease after initial episode of ARF is usually considered as a predisposing factor for IE. We hereby present a biopsy-proven case of IE co-diagnosed with the first episode of ARF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18785409183000
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http://dx.doi.org/10.1016/j.jccase.2017.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149577PMC
May 2018
4 Reads

Fever and large pericardial effusion after valve surgery: can be malaria.

Asian Cardiovasc Thorac Ann 2018 Sep 30:218492318805337. Epub 2018 Sep 30.

Department of Cardiothoracic Surgery, Ahalia Hospital-Mussafah, Abu Dhabi, United Arab Emirates.

A 37-year-old man underwent mechanical mitral valve replacement for rheumatic heart disease. One week after discharge, he presented with high-grade fever with chills, malaise, and shortness of breath. Echocardiography showed pericardial effusion with no evidence of vegetation. Read More

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http://dx.doi.org/10.1177/0218492318805337DOI Listing
September 2018
2 Reads

Presence of increased inflammatory infiltrates accompanied by activated dendritic cells in the left atrium in rheumatic heart disease.

PLoS One 2018 27;13(9):e0203756. Epub 2018 Sep 27.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

Aims: Left atrial (LA) structural remodelling develops in rheumatic heart disease (RHD) according to the disease severity of the mitral valve and the presence of atrial fibrillation. Sustained active inflammation has been previously reported in the LA of patients with RHD, suggesting a direct role of cell-mediated immunity in the pathogenesis of LA remodelling. Dendritic cells (DCs) have a major antigen-presenting role, and are known as crucial modulators of innate and adaptive immunity. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203756PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159861PMC
September 2018
20 Reads

Murmurs of Politics and Economics.

Authors:
Nikola Lilic

N Engl J Med 2018 Sep;379(13):1202-1203

From the Department of Surgery, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1056/NEJMp1806115DOI Listing
September 2018
9 Reads

Streptococcal Serology in Acute Rheumatic Fever Patients: Findings From 2 High-income, High-burden Settings.

Pediatr Infect Dis J 2019 Jan;38(1):e1-e6

Royal Darwin Hospital.

Background: Globally, there is wide variation in streptococcal titer upper limits of normal (ULN) for antistreptolysin O (ASO) and anti-deoxyribonuclease B (ADB) used as an evidence of recent group A streptococcal infection to diagnose acute rheumatic fever (ARF).

Methods: We audited ASO and ADB titers among individuals with ARF in New Zealand (NZ) and in Australia's Northern Territory. We summarized streptococcal titers by different ARF clinical manifestations, assessed application of locally recommended serology guidelines where NZ uses high ULN cut-offs and calculated the proportion of cases fulfilling alternative serologic diagnostic criteria. Read More

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http://dx.doi.org/10.1097/INF.0000000000002190DOI Listing
January 2019
2 Reads

[Improved early diagnostics of rheumatic diseases : Monocentric experiences with an open rheumatological specialist consultation].

Z Rheumatol 2018 Nov;77(9):844-849

Standort Berlin Buch, Immanuel Krankenhaus Berlin, Lindenberger Weg 19, 13125, Berlin, Deutschland.

Aim Of The Project: To establish an open rheumatological outpatient consultation service for early diagnosis of inflammatory rheumatic diseases and initiation of further diagnostics and treatment.

Methods: In 2015 an open consultation service was initiated for patients with signs of an early rheumatic disease after referral by primary care physicians. Patients could attend once a week without the need for a prior appointment if they fulfilled at least one of the following criteria: positive rheumatoid factor, increased CRP, anti-CCP antibody or antinuclear antibody, joint pain or back pain for over 3 months, swollen joints, fever of unknown origin or acute muscle pain with or without headache of unknown origin. Read More

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http://dx.doi.org/10.1007/s00393-018-0540-4DOI Listing
November 2018
1 Read

Rheumatic heart disease awareness in the South West region of Cameroon: A hospital based survey in a Sub-Saharan African setting.

PLoS One 2018 25;13(9):e0203864. Epub 2018 Sep 25.

Clinical Research Education, Networking and Consultancy, Douala, Cameroon.

Background: Early diagnosis and adequate treatment of Group A streptococcal throat infection is an important initial stage in the primary prevention of acute rheumatic fever and rheumatic heart disease. This preventable condition associated with high mortality rates mandates a thorough understanding by the general public and the health.

Objective: The aim of the study was to assess the level of awareness about different aspects of rheumatic heart disease in patients coming to the outpatient department of the Buea regional Hospital, South West region of Cameroon. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203864PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155442PMC
September 2018
5 Reads

FDG PET/CT Findings in TAFRO Syndrome.

Clin Nucl Med 2018 Nov;43(11):828-829

Division of Rheumatic Diseases, National Center for Global Health and Medicine, Tokyo, Japan.

A 67-year-old woman with prolonged fever, thrombocytopenia, and renal dysfunction underwent FDG PET/CT to evaluate underlying causes, including malignancy. PET/CT showed FDG uptake in ascites, subcutaneous edema, lymph nodes, spleen, and bone marrow. Subsequent bone marrow biopsy revealed myelofibrosis, and laboratory testing showed elevated concentrations of interleukin 6 in serum and ascites. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002278DOI Listing
November 2018
3 Reads

Rheumatoid nodule on the anterior mitral valve leaflet.

J Card Surg 2018 Oct 10;33(10):643-645. Epub 2018 Sep 10.

Department of Cardiothoracic Surgery, Wythenshawe Hospital, Wythenshawe, Manchester, UK.

Symptomatic cardiac rheumatoid nodules are a rare but recognized manifestation of rheumatoid arthritis. We describe the surgical management of a rheumatic nodule involving the anterior leaflet of the mitral valve. Read More

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http://doi.wiley.com/10.1111/jocs.13809
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http://dx.doi.org/10.1111/jocs.13809DOI Listing
October 2018
11 Reads

Clinical Characteristics, Complications, and Treatment Practices in Patients With RHD: 6-Year Results From HP-RHD Registry.

Glob Heart 2018 12 6;13(4):267-274.e2. Epub 2018 Sep 6.

Department of Cardiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Background: Despite the high prevalence of rheumatic heart disease (RHD) in developing countries such as India, data on characteristics, complications, and treatment practices are lacking. The HP-RHD (Himachal Pradesh Rheumatic Heart Disease) registry aimed at reporting these parameters in patients with RHD from a northern state of India.

Methods: A total of 2,005 consecutive patients of RHD were enrolled over a period of 6 years (2011 to 2016) in the present study. Read More

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http://dx.doi.org/10.1016/j.gheart.2018.06.001DOI Listing
December 2018
7 Reads

Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues.

Glob Public Health 2018 Sep 7:1-13. Epub 2018 Sep 7.

a Telethon Kids Institute , Perth , Australia.

Rheumatic heart disease (RHD) is an avoidable disease of poverty that persists predominantly in low resource settings and among Indigenous and other high-risk populations in some high-income nations. Following a period of relative global policy inertia on RHD, recent years have seen a resurgence of research, policy and civil society activity to tackle RHD; this has culminated in growing momentum at the highest levels of global health diplomacy to definitively address this disease of disadvantage. RHD is inextricably entangled with the global development agenda, and effective RHD action requires concerted efforts both within and beyond the health policy sphere. Read More

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http://dx.doi.org/10.1080/17441692.2018.1515970DOI Listing
September 2018
3 Reads

Demographic and Psychological Factors Associated with Feelings of Antibiotic Entitlement in New Zealand.

Antibiotics (Basel) 2018 Sep 5;7(3). Epub 2018 Sep 5.

School of Psychology, University of Auckland, Auckland 1010, New Zealand.

Patients' expectations of being prescribed antibiotics can have an important influence on inappropriate prescribing. Therefore, it is important to understand the drivers of patients' antibiotic expectations. The 2015/16 New Zealand Attitudes and Values Study measured sense of entitlement to antibiotics in a nationally representative sample of New Zealanders ( = 13,484). Read More

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http://www.mdpi.com/2079-6382/7/3/82
Publisher Site
http://dx.doi.org/10.3390/antibiotics7030082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165134PMC
September 2018
4 Reads