1,187,890 results match your criteria Acute Pulmonary Embolism Helical CT
J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.
Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Background And Aim: The treat-to-target strategy has emerged in ulcerative colitis management. Mucosal healing is the best target, albeit not in induction therapy of acute diseases as clinical conditions vary over a short duration. To determine the targets during induction therapy for acute ulcerative colitis, we identified markers to predict mucosal healing at 3 and 12 months of initiating the induction therapy. Read More
Nicotine Tob Res 2018 Dec 14. Epub 2018 Dec 14.
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Introduction: Despite the overall decline in the prevalence of cigarette use in the United States, menthol cigarette use among smokers is rising, and evidence shows that it may lead to more detrimental effects on public health than regular cigarette use. One of the mechanisms by which nicotine sustains tobacco use and dependence is due to its cognitive enhancing properties, and basic science literature suggests that menthol may also enhance nicotine's acute effect on cognition.
Aims And Methods: The purpose of this review is to suggest that the cognitive enhancing effects of menthol may be a potentially important neuropsychological mechanism that has yet to be examined. Read More
Invest Ophthalmol Vis Sci 2018 Dec;59(15):5924-5931
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Purpose: To clarify the distinct molecular pathogenesis of central serous chorioretinopathy (CSC) and pachychoroid neovasculopathy (PNV).
Methods: Aqueous humor (AH) was collected from 18 acute CSC, 20 chronic CSC, and 20 PNV patients. Concentrations of 30 cytokines in the AH were analyzed using a multiplex bead immunoassay, and the cytokine profiles were compared among these three groups of patients. Read More
J Natl Cancer Inst 2018 Dec 14. Epub 2018 Dec 14.
University of California San Diego School of Medicine, UCSD School of Medicine, La Jolla, CA.
Background: Chimeric antigen receptor T-cell (CAR-T) therapy is a promising new class of cancer therapy but has a high up-front cost. We evaluated the cost-effectiveness of CAR-T therapy among pediatric patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL).
Methods: We built a microsimulation model for pediatric patients with relapsed/refractory B-ALL receiving either CAR-T therapy or standard of care. Read More
Nicotine Tob Res 2018 Dec 14. Epub 2018 Dec 14.
Department of Psychology, Louisiana State University, Baton Rouge, LA, USA.
Introduction: Despite negative effects of smoking, smokers have difficulty quitting, suggesting a need for additional strategies to help them quit. A single-session hatha yoga intervention acutely reduced craving among nicotine-deprived smokers not attempting to reduce or quit, yet it is unknown if it reduces craving among those attempting to change their smoking. Thus, the current study tested the efficacy of a single-session hatha yoga intervention for acutely reducing craving among smokers attempting to reduce or quit smoking. Read More
Chemosphere 2018 Dec 10;219:463-471. Epub 2018 Dec 10.
Centre de Biotechnologie de Borj Cedria (LR15CBBC02), Laboratoire des Plantes Extrèmophiles, BP 901 2050 Hammam-Lif, Tunisia. Electronic address:
Sesuvium portulacastrum, a halophyte with high tolerance to heavy metals like Cd, Pb and Ni is considered for phytoremediation of metal contaminated saline soils. The tolerance to a selected metal ion could, by hypothesis, be stimulated through in vitro adaptation and regeneration of the plant. Seedlings obtained by in vitro micro-propagation, were exposed to 0, 25 and 50 μM Ni, as NiCl, in agar-based medium for 30 days. Read More
Int J Nurs Stud 2018 Nov 27;90:21-30. Epub 2018 Nov 27.
School of Education, Health, and Social Studies, Dalarna University, Falun, Sweden.
Background: The approach and style of leaders is known to be an important factor influencing the translation of research evidence into nursing practice. However, questions remain as to what types of roles are most effective and the specific mechanisms through which influence is achieved.
Objectives: The aim of the study was to enhance understanding of the mechanisms by which key nursing roles lead the implementation of evidence-based practice across different care settings and countries and the contextual factors that influence them. Read More
Thromb Res 2018 Dec 6;174:16-23. Epub 2018 Dec 6.
Department of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
Background: Patients with warfarin have a potential risk of warfarin-related nephropathy, which could result in the discontinuation of anticoagulation therapy. The question of whether non-vitamin K antagonist oral anticoagulants (NOACs) use is associated with increased risk of renal impairment in atrial fibrillation (AF) patients remains unanswered.
Methods: Studies were systematically searched through Medline, Embase, Cochrane Library databases, and ClinicalTrials. Read More
Compr Psychiatry 2018 Dec 5;89:1-6. Epub 2018 Dec 5.
Department of Social Work and Social Administration, University of Hong Kong, Hong Kong. Electronic address:
Purpose: Although high expressed emotions (EE) is one of the most significant predictors for schizophrenic relapse, the assessment of EE is often impeded by the demanding Camberwell Family Interview (CFI) that is required to be conducted by specifically trained staff. To enable a more efficient assessment of EE, we developed the 12-item Concise Chinese Level of Expressed Emotion Scale (CCLEES) and reported its predictive and concurrent validity in this study.
Methods: A one-year prospective study design was adopted. Read More
Behav Brain Res 2018 Dec 11. Epub 2018 Dec 11.
University of Saskatchewan, Department of Physiology, Saskatoon, SK, Canada.
Abnormalities in social behavior are a co-morbid symptom of idiopathic generalized epilepsies such as childhood absence epilepsy. The Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model is a spontaneously occurring absence epilepsy phenotype closely correlated to that of human absence epilepsies. Similar to the human conditions, GAERS display social abnormalities. Read More
Behav Brain Res 2018 Dec 11. Epub 2018 Dec 11.
Department of Pharmacology, School of Pharmacy, Physiology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Neuroanesthesia Laboratory, Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:
Here, we aimed to investigate the effects of fluoxetine on morphine-induced analgesia, as well as preventive effects of it on morphine induced tolerance and dependence in mice. We also elucidate the involvement of L-type Ca channels in these phenomena. To induce morphine tolerance, mice were treated with morphine (50 mg/kg) for 3 consecutive days. Read More
Brain Behav Immun 2018 Dec 11. Epub 2018 Dec 11.
Departament de Biologia Cel·lular, Fisiologia i Immunologia, Institut de Neurociències, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Bellaterra, Catalonia, 08193, Spain. Electronic address:
Lysophosphatidic acid (LPA) is an extracellular lipid mediator involved in many physiological functions by signaling through six known G-protein-coupled receptors (LPA-LPA). In the central nervous system (CNS), LPA mediates a wide range of effects, including neural progenitor cell physiology, astrocyte and microglia activation, neuronal cell death, axonal retraction, and contributions to pain, schizophrenia and hydrocephalus. We recently reported that LPA-LPA signaling mediates functional deficits and myelin loss after spinal cord injury (SCI). Read More
Brain Behav Immun 2018 Dec 11. Epub 2018 Dec 11.
Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232-2650, USA.
Background: Prenatal life stress exposure is linked to dysregulated immune function and chronic inflammatory disease in offspring, but we know little about its effects on infant immune response during viral infection.
Method: To address this issue, we examined associations between prenatal life stress exposure and infant upper-airway inflammatory markers during acute respiratory infection (ARI) using data from a prospective, population-based birth-cohort study (N=180). Infant inflammation was measured as a continuous latent factor within a structural equation modeling framework using nasal wash concentrations of interleukin-1β, interleukin-6, and tumor necrosis factor-α. Read More
Appetite 2018 Dec 11. Epub 2018 Dec 11.
Department of Foods and Nutrition, University of Georgia, Athens, GA, USA. Electronic address:
Background: Modifying the type of dietary fat consumed may impact appetite, therefore having implications in weight management.
Objective: To test the effects of a 5-day, high-fat diet rich in poly-unsaturated fatty acids (PUFAs) and a diet rich in mono-unsaturated fatty acids (MUFAs) on markers of appetite.
Methods: Fifteen normal weight men participated in a randomized cross-over design with two controlled feeding trials (3d lead-in diet, pre-diet visit, 5d PUFA- or MUFA-rich diet, post-diet visit). Read More
Life Sci 2018 Dec 11. Epub 2018 Dec 11.
Department of Cell and Molecular Biology, Institute of Acute Abdominal Diseases of Integrated Traditional Chinese and Western Medicine, Tianjin Nankai Hospital, Tianjin 300100, China; Nankai Clinical College, Tianjin Medical University, Tianjin 300107, China. Electronic address:
Aims: Pancreatic stellate cells (PSCs) play a critical role in the development of pancreatic fibrosis. Any agents that can affect PSC activation could become potential candidates for treating pancreatic fibrosis. FTY720 can attenuate chronic pancreatic fibrosis by suppressing T-cell infiltration, but its effect on PSCs remains unknown. Read More
Life Sci 2018 Dec 11. Epub 2018 Dec 11.
Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address:
Drug-induced liver toxicity is the most frequent cause of acute liver failure worldwide. Hepatotoxicity caused by acetaminophen (ACT) overdose is mediated by its metabolic product promoting oxidative stress and activation of inflammatory mediators. Nuclear factor erythroid-related factor-2 (Nrf-2) induces the release of cytoprotective enzymes in response to electrophilic or oxidative stress and is considered a promising therapeutic target. Read More
Fungal Genet Biol 2018 Dec 11. Epub 2018 Dec 11.
Department of Cellular and Molecular Biology, Centro de Investigaciones Biológicas CSIC, Ramiro de Maeztu 9, Madrid 28040, Spain. Electronic address:
Coatomer-I (COPI) is a heteromeric protein coat that facilitates the budding of membranous carriers mediating Golgi-to-ER and intra-Golgi transport. While the structural features of COPI have been thoroughly investigated, its physiological role is insufficiently understood. Here we exploit the amenability of A. Read More
Neuroscience 2018 Dec 11. Epub 2018 Dec 11.
Northeastern Univ, Center for Translational NeuroImaging, Boston, MA, USA. Electronic address:
The present study was designed to use blood-oxygen-level dependent (BOLD) imaging to "fingerprint" the change in activity in response to oxycodone (OXY) in drug naïve rats before and after repeated exposure to OXY. It was hypothesized that repeated exposure to OXY would initiate adaptive changes in brain organization that would be reflected in an altered response to opioid exposure. Male rats exposed to OXY repeatedly showed conditioned place preference, evidence of drug seeking behavior and putative neuroadaptation. Read More
J Invertebr Pathol 2018 Dec 11. Epub 2018 Dec 11.
INRA, UR 406 Abeilles et Environnement - Site Agroparc - Domaine St Paul - 228, Route de l'aérodrome CS40509 - 84914 Avignon Cedex 9, France.
Many of the physiological traits in insects are shaped by environmental temperatures, which can influence their interactions with pathogens. Therefore, quantifying the thermal responses of the host-pathogen system is crucial for better understanding and predicting their dynamics due to environmental changes. This is particularly important in honey bees, which are experiencing severe colony losses around the world, notably due to infection with the Deformed wing virus (DWV). Read More
Surv Ophthalmol 2018 Dec 11. Epub 2018 Dec 11.
Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Vernal keratoconjunctivitis, a chronic, bilateral, seasonal allergic inflammatory disease of the eye, is an important cause of visual debilitation and impairment of quality of life in children and young adults in certain parts of the world such as the Mediterranean areas, Central and West Africa, the Middle East, Japan, the Indian subcontinent, and South America. It usually has a self-limiting course; however, in a few cases the disease is recurrent and leads to long-term visual disabling complications like keratoconus and limbal stem cell deficiency. The main pathogenic mechanism is IgE mediated; however, there may be non-IgE and certain non-specific hypersensitivity mechanisms. Read More
Cochrane Database Syst Rev 2018 Dec 14;12:CD012939. Epub 2018 Dec 14.
ENT Department, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK, CB2 0QQ.
Background: More than 400,000 cases of oropharyngeal squamous cell cancer (OPSCC) are diagnosed every year worldwide and this is rising. Much of the increase has been attributed to human papillomavirus (HPV). HPV-positive OPSCC patients are often younger and have significantly improved survival relative to HPV-negative patients. Read More
PLoS One 2018 14;13(12):e0209088. Epub 2018 Dec 14.
Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Background: We investigated the role of nutritional risk index (NRI) in predicting 1-year mortality in patients with acute decompensated heart failure (ADHF).
Methods: Among 5,625 cohort patients enrolled in Korean Acute Heart Failure (KorAHF) Registry, a total of 5,265 patients who were possible to calculate NRI [NRI = (1.519 x serum albumin [g/dl]) + (41. Read More
PLoS One 2018 14;13(12):e0208847. Epub 2018 Dec 14.
Group of Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova de Lleida,IRBLleida, Universitat de Lleida, Lleida, Catalonia, Spain.
Introduction: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common reason for presentation to emergency departments (ED), but the management of these episodes is often heterogeneous regardless of their potential impact on short-term adverse outcomes.
Methods: This was a longitudinal, retrospective study of all patients >40 years old admitted to the ED of two Spanish teaching hospitals for an AECOPD between January 1st and May 31st, 2016. All data were collected from electronic medical records. Read More
PLoS One 2018 14;13(12):e0207980. Epub 2018 Dec 14.
Department of Cardiology, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Purpose: Quantitative computed tomography (QCT) provides important prognostic information of coronary atherosclerosis. We investigated intraobserver and interobserver QCT reproducibility in asymptomatic individuals, patients with acute chest pain without acute coronary syndrome (ACS), and patients with acute chest pain and ACS.
Methods: Fifty patients from each cohort, scanned between 01/02/2010-14/11/2013 and matched according to age and gender, were retrospectively assessed for inclusion. Read More
PLoS One 2018 14;13(12):e0209295. Epub 2018 Dec 14.
Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
CD25 is expressed on leukemic cells in 10-20% cases of acute myeloid leukemia (AML), and its expression is associated with poor prognosis. We reevaluated the relationship between CD25 expression and the leukemia-initiating cell (LIC) properties of AML using a patient-derived xenograft model. We divided lineage marker-negative (Lin-) CD34+CD38- or Lin-CD34+ cells from CD25-positive AML into CD25-positive and -negative populations, and then transplanted each population into NOD. Read More
Medwave 2018 Dec 11;18(8):e7370. Epub 2018 Dec 11.
Proyecto Epistemonikos, Santiago, Chile; Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile; Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.
Introduction: The treatment of acute appendicitis using laparoscopy reduces the risk of wound infection, hospitalization time and return to normal activity. However, it increases the risk of intra-abdominal abscess, which is one the main complications of complicated appendicitis.
Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More
J Cardiovasc Med (Hagerstown) 2018 Dec 12. Epub 2018 Dec 12.
Department of Cardiology, 'Sapienza' University of Rome, Rome, Italy.
Med Sci Sports Exerc 2018 Dec 13. Epub 2018 Dec 13.
Department of Human Studies.
Exercise is known to improve insulin sensitivity (SI), however studies to date have been confounded by negative energy deficits following exercise.
Purpose: The primary objective of this study was to assess the effect of 8-16 weeks of aerobic exercise training on the SI of untrained women under rigorously controlled energy balanced conditions. The secondary objective was to determine if one acute bout of moderate (MIC)- or high (HII)-intensity exercise further affected SI. Read More
Pediatr Infect Dis J 2018 Dec 13. Epub 2018 Dec 13.
Department of Pediatrics, Sendai Medical Center, 2-8-8 Miyagino, Sendai 983-8520, Japan.
Background: Kawasaki disease (KD) is an acute, systemic vasculitis syndrome that occurs in children. The clinical symptoms and epidemiological features of KD strongly suggest that KD is triggered by unidentified infectious agents in genetically predisposed patients. In addition, a number of studies have described the role of B cells in the development of KD. Read More
J Pediatr Hematol Oncol 2019 Jan;41(1):e12-e17
Department of Pediatrics, Aarhus University Hospital Skejby, Aarhus.
Background: As more children survive acute myeloid leukemia (AML) it is increasingly important to assess possible late effects of the intensive treatment. Hearing loss has only sporadically been reported in survivors of childhood AML. We assessed hearing status in survivors of childhood AML treated with chemotherapy alone according to 3 consecutive NOPHO-AML trials. Read More
Curr Opin Pulm Med 2018 Dec 12. Epub 2018 Dec 12.
Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital National Clinical Research Center of Respiratory Diseases Capital Medical University.
Purpose Of Review: This review summarizes the latest discoveries regarding the use of clinical indicators and biomarkers to guide antibiotic use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and it analyzes the advantages and disadvantages of various indicators and markers.
Recent Findings: For AECOPD patients admitted to emergency departments and medical wards, procalcitonin (PCT)-guided antibiotic therapy reduced antibiotic use without adverse outcomes. In contrast, for severe AECOPD patients admitted to ICUs, PCT-guided antibiotic therapy increased the overall mortality in a 3-month follow-up period, and antibiotic use was not decreased. Read More
J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.
Southern Cross University and Griffith University, Gold Coast, Australia (Dr Stolic); Menzies Health Institute Queensland and Griffith University, Gold Coast, Australia (Dr Lin); and Intensive Care Unit, Princess Alexandra Hospital, Griffith University and Menzies Health Institute, Brisbane, Australia (Dr Mitchell).
Background: Poorly managed acute coronary syndrome symptoms increase the risk of subsequent cardiovascular events.
Purpose: The aim of this study was to evaluate the effectiveness of symptom management patient education on the knowledge of sublingual nitroglycerin for people with acute coronary syndrome.
Methods: A randomized controlled trial was used to evaluate the 3-resource intervention. Read More
J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.
Department of Medicine (Drs Krol, Jolly Graham, and White and Mr English), Center for Advanced Clinical Practice (Ms Allen), and Duke University School of Nursing (Ms Matters), Duke University Medical Center, Durham, North Carolina.
Background: Individuals discharged from the hospital to skilled nursing facilities (SNFs) experience high rates of unplanned hospital readmission, indicating opportunity for improvement in transitional care.
Local Problem: Local physicians providing care in SNFs were not associated with the discharging hospital health care system. As a result, substantive real-time communication between hospital and SNF physicians was not occurring. Read More
J Acquir Immune Defic Syndr 2018 Dec 6. Epub 2018 Dec 6.
AIDS Clinical Center and.
Background: Acute hepatitis C virus (HCV) infection is increasing among HIV-1-infected individuals in Tokyo. Appropriate clinical management is needed.
Setting: To delineate the epidemiological status of HCV transmission, we analyzed stocked plasma samples of HCV/HIV-1-coinfected patients seen at the largest referral center for HIV care in Tokyo. Read More
Anesth Analg 2019 Jan;128(1):e17
J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.
Plastic, Reconstructive, and Aesthetic Surgery Department of Mersin University Medical Faculty, Mersin, Turkey.
Ultra-thin porous polyethylene has been widely preferred in orbital blow out fracture repair for many years as a safe and stable material. Delayed complications related to the implant in orbital blow out fracture repair are very rare and usually begin as a periorbital inflammation. Infections and tissue reaction to the foreign body are regarded as main causes for implant-related inflammation of which symptoms may vary among the patients and may involve subacute and chronic eyelid swelling, skin redness, pain, conjunctival injection, proptosis, and acute orbital inflammation. Read More
Clin J Sport Med 2018 Dec 13. Epub 2018 Dec 13.
Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Objective: To determine the acute effects of repetitive soccer heading on postural control.
Design: Prospective study; participants were divided into 2 groups: a soccer heading group and a control group.
Setting: Biomechanics laboratory. Read More
Ann Surg 2018 Dec 13. Epub 2018 Dec 13.
Department of Surgery, Division of Trauma, Burn and Surgical Critical Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Objective: The aim of this study was to determine factors associated with patient-reported outcomes, 6 to 12 months after moderate to severe injury.
Summary Of Background Data: Due to limitations of trauma registries, we have an incomplete understanding of factors that impact long-term patient-reported outcomes after injury. As 96% of patients survive their injuries, several entities including the National Academies of Science, Engineering and Medicine have called for a mechanism to routinely follow trauma patients and determine factors associated with survival, patient-reported outcomes, and reintegration into society after trauma. Read More
J Oncol Pract 2018 Dec 14:JOP1800162. Epub 2018 Dec 14.
UCLA Jonsson Comprehensive Cancer Center; UCLA Anderson School of Management; UCLA Schools of Medicine and Public Health, Los Angeles; UC Davis Center for Healthcare Policy and Research, Davis, CA; and University of Texas Health Sciences Center, San Antonio, TX.
Purpose:: According to the Institute of Medicine, high-quality cancer care should include effective communication between clinicians and patients about the risks and benefits, expected response, and impact on quality of life of a recommended therapy. In the delivery of oncology care, the barriers to and facilitators of communication about potential long-term and late effects, post-treatment expectations, and transition to survivorship care have not been fully defined.
Patients And Methods:: We collected qualitative data through semistructured interviews with medical oncologists and focus groups with breast cancer survivors and applied the Theoretical Domains Framework to systematically analyze and identify the factors that may influence oncologists' communication with patients with breast cancer about the long-term and late effects of adjuvant therapy. Read More
Syst Biol Reprod Med 2018 Dec 14:1-16. Epub 2018 Dec 14.
b Division of Pharmacology and Toxicology , CSIR- Indian Institute of Chemical Technology , Hyderabad , India.
We aimed to survey the monogenic causes of disorders of sex development (DSD) and thereby its prevalence in India. This study revealed mutations resulting in androgen insensitivity syndrome, 5α-reductase type 2 deficiency, and gonadal dysgenesis were commonly reported. Intriguingly, AR deficits were the most prevalent (32 mutations) and of 11/26 missense mutations were in exons 4-8 (encoding ligand binding domain). Read More
Emotion 2018 Dec 13. Epub 2018 Dec 13.
Department of Psychology, University of California, Davis.
Acute stress impairs working memory (i.e., the ability to update and keep information in mind). Read More
G Ital Med Lav Ergon 2018 Dec;40(4):248-256
Physical Medicine and Rehabilitation Unit, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; University of Pavia, Italy.
Objectives: Systemic sclerosis is a multisystem autoimmune disease that causes chronic widespread obliterative vasculopathy of the small arteries associated with various degrees of tissue fibrosis. The prognosis of the disease depends largely on the visceral involvement; however musculoskeletal involvement is an important factor to functional disability. Suffering from a chronic auto-immune disease, such as Systemic Sclerosis, compromises the quality of life and the work ability. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1469-1471
Department of Otorhinolaryngology, Peking Union Medical College Hospital, Peking UnionMedical College, Chinese Academy of Medical Sciences, Beijing, 100730, China.
To summarize the clinical characteristics of congenital pyriform fistula with acute suppurative thyroiditis as the initial presentation. A total of 71 patients with congenital pyriform sinus fistula were treated, of which 33 cases had acute suppurative thyroiditis as the first symptom. For the patients with congenital pyriform sinus fistula who have acute suppurative thyroiditis as the first symptom, infection should be controlled first. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1377-1382
Department of Otolaryngology, the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou, 325000, China.
To explore the prevalence of allergy in patients with acute rhinosinusitis (ARS) and evaluate the severity of symptoms in ARS children with or without allergy.Two hundred and seven children (4-12 years of age) with ARS and 85 children of control group were included in our research from June, 2016 to January, 2018. We use questionaire to collect the basic information of pediatric patients. Read More
Vopr Virusol 2018 ;63(5):233-239
Federal State Research Institute of Influenza, St. Petersburg, 197376, Russian Federation.
The etiological structure of influenza and other acute respiratory viral infections including their rate of incidence in St. Petersburg and Leningrad region during 4 epidemic seasons has been studied. Seasonality of some respiratory viruses was shown and peaks of circulation of RSV, adenovirus, parainfluenza viruses, rhinovirus, bocavirus, metapneumovirus and coronavirus were marked. Read More
Vopr Virusol 2018 ;63(5):218-223
National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya, Moscow, 123098, Russian Federation.
Increased protease activity and a significant amount of granzyme B were observed in in organs of mice infected with acute herpes simplex virus HSV-1 with the introduction of Stimforte (100 or 250 µg/mouse). Thus, this drug activates killer cells, which play an extremely important role in the suppression of HSV-1 infection. Although the administration of Stimforte (100 μg/mouse) to intact mice results in the activation of IFN-β production and does not activate the production of IFN-λ, Stimforte administration to animals infected with HSV-1 reduces production of IFN-β in serum, brain and lungs, whereas the production of IFN-λ considerably increases as the result of administration of 100 μg/mouse of Stimforte. Read More
Klin Lab Diagn 2018 ;63(1):51-54
The state budget institution of health care "The clinical center of prevention and struggle with AIDS" of the Minzdrav of the Krasnodar kraii, 350015, Krasnodar, Russia.
The purpose of study is the clinical laboratory characteristic of acquired acute cytomegalovirus infection in nonimmunocompromised adult patients. The sampling included 75 patients with acquired acute cytomegalovirus infection admitted to the specialized clinical infection hospital of the Minzdrav of the Krasnodar kraii. The verifcation of diagnosis was implemented using serological tests and polymerase chain reaction. Read More
G Ital Nefrol 2018 Dec;35(6)
S.C. Nefrologia, Dialisi e Trapianto U. AOU Città della Salute e della Scienza di Torino, Torino, Italia.
Acute Kidney Injury (AKI) is a frequent complication of multiple myeloma (MM) with unfavorable prognostic significance. Light chains removal, combined with hematological therapy (CT) seems to offer significant benefits to renal function recovery (RFR). The SUPRA HFR, through the combination of high cut-off membrane without albumin loss and adsorbent cartridge, represents one of the "emerging" light chain removal methods. Read More
G Ital Nefrol 2018 Dec;35(6)
Unità di Fisiopatologia dell'Insufficienza Renale Acuta e Cronica - Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.
Acute Kidney Injury (AKI) is an important issue for the healthcare system, as it is associated with high mortality and increased risk of readmission, with consequent elevated healthcare resource utilization. We investigated the incidence of AKI based on the examination of the discharge cards of all patients admitted between January 1 2011 and December 31 2015 at the Parma University Hospital, as well as the frequency and type of 30-day hospital readmission in the patients discharged with a first AKI diagnosis (index admission). The mean pooled 5-year incidence of AKI was 2. Read More
Isr Med Assoc J 2018 Dec;20(12):788-789
Detpartment of Child and Adolescent Psychiatry, Jerusalem Mental Health Center, Eitanim Psychiatric Hospital, Hadassah-Hebrew University School of Medicine, Jerusalem, Israel.