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IJID Reg 2022 Jun 24;3:135-137. Epub 2022 Mar 24.

Samaritan Surgical Centre, Addis Ababa, Ethiopia.

Background: Fascioliasis is a zoonotic infection caused by . (liver fluke). Although infrequently diagnosed, it is emerging as a helminth infection of public health importance in many parts of the world. Read More

ANZ J Surg 2022 Jun 25. Epub 2022 Jun 25.

Department of Vascular Surgery, Hollywood Hospital, Perth, Western Australia, Australia.

Background: Splanchnic vein thrombosis (SVT) is an uncommon yet potentially life-threatening manifestation of venous thromboembolism. The aim of this study was to present a retrospective analysis of a cohort of Western Australian patients diagnosed with SVT on imaging study, and a review of the literature surrounding the aetiology, location, anticoagulation treatment and outcomes of SVT.

Methods: All patients diagnosed with SVT over a five-year period from 2015 to 2020 in three tertiary hospitals in Western Australia were identified by using an electronic search engine of imaging reports. Read More

SA J Radiol 2022 9;26(1):2385. Epub 2022 May 9.

Department of Radiodiagnosis, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.

Pancreatic pseudocyst is a common complication that can occur following acute or chronic pancreatitis. Commonly, they are peripancreatic in location. Rarely, they can extend to the mediastinum, and further extension to the neck is even rarer. Read More

Medicina (Kaunas) 2022 Jun 11;58(6). Epub 2022 Jun 11.

Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea.

Acute pancreatitis has a diverse etiology and natural history, and some patients have severe complications with a high risk of mortality. The prediction of the severity of acute pancreatitis should be achieved by a careful ongoing clinical assessment coupled with the use of a multiple-factor scoring system and imaging studies. Over the past 40 years, various scoring systems have been suggested to predict the severity of acute pancreatitis. Read More

Eur Radiol 2022 Jun 21. Epub 2022 Jun 21.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro Gangnam-gu, Seoul, 06351, Republic of Korea.

Objectives: To identify useful features to predict hidden pancreatic malignancies in patients with main pancreatic duct (MPD) abrupt cutoff and dilatation, but without visible focal pancreatic lesions on CT.

Methods: This retrospective study included 92 patients (mean age, 63.4 ± 10. Read More

World J Gastroenterol 2022 May;28(20):2201-2213

Department of Medicine B (Gastroenterology, Hepatology, Endocrinology, Clinical Infectiology), University Hospital Muenster, Muenster 48149, Germany.

Background: Patients with primary sclerosing cholangitis (PSC) are at a high risk of developing cholestatic liver disease and biliary cancer, and endoscopy is crucial for the complex management of these patients.

Aim: To clarify the utility of recently introduced digital single-operator video cholangioscopy (SOVC) for the endoscopic management of PSC patients.

Methods: In this observational study, all patients with a history of PSC and in whom digital SOVC (using the SpyGlass DS System) was performed between 2015 and 2019 were included and retrospectively analysed. Read More

Front Med (Lausanne) 2022 26;9:875263. Epub 2022 May 26.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Objectives: To investigate the dynamic changes in gastric varices in patients with acute pancreatitis (AP) and to develop a novel nomogram for the early prediction of sinistral portal hypertension (SPH).

Methods: This was a retrospective, case-control study with an analysis of the quantitative, dynamic computed tomography imaging results of SPH in patients with moderate and severe AP with a long-term follow-up. Multivariate logistic regression analysis and nomogram were employed. Read More

Pancreatology 2022 Jun 4. Epub 2022 Jun 4.

Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, 310052, PR China; Pediatric Endoscopy Center and Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, 310052, PR China. Electronic address:

Objective: To investigate the clinical characteristics, diagnosis, and treatment of asparaginase-associated pancreatitis (AAP) in children to assess the risk factors of AAP and improve its clinical prognosis.

Methods: We performed a retrospective analysis of 24 patients with AAP who suffered from acute lymphoblastic leukemia (ALL) and received asparaginase chemotherapy, and who were admitted to the Children's Hospital of Zhejiang University School of Medicine from January 2009 to January 2019. We analyzed the general situation, drug application, clinical manifestations, laboratory tests, imaging findings, treatment, and prognosis. Read More

Pancreatology 2022 Jun 10. Epub 2022 Jun 10.

Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: The functional and morphological recovery following an episode of acute pancreatitis (AP) in children still remains ill understood as research exploring this is limited. We aimed to characterize the morphological and functional changes in pancreas following AP and ARP (acute recurrent pancreatitis) in children.

Methods: Children with AP were followed prospectively and assessed at two time points at least 3 months apart, with the first assessment at least 3 months after the AP episode. Read More

Endosc Ultrasound 2022 Jun 8. Epub 2022 Jun 8.

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

Disconnected pancreatic duct syndrome (DPDS) is an important and common complication of acute necrotizing pancreatitis. Endoscopic approach has been established as the first-line treatment for pancreatic fluid collections (PFCs) with less invasion and satisfactory outcome. However, the presence of DPDS significantly complicates the management of PFC; besides, there is no standardized treatment for DPDS. Read More

Open Biol 2022 Jun 15;12(6):210273. Epub 2022 Jun 15.

Anatomy and Structural Biology, Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA.

Pancreatitis and pancreatic ductal adenocarcinoma (PDAC) are grave illnesses with high levels of morbidity and mortality. Intravital imaging (IVI) is a powerful technique for visualizing physiological processes in both health and disease. However, the application of IVI to the murine pancreas presents significant challenges, as it is a deep, compliant, visceral organ that is difficult to access, easily damaged and susceptible to motion artefacts. Read More

Dig Endosc 2022 Jun 15. Epub 2022 Jun 15.

Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.

Urgent or emergency endoscopic retrograde cholangiopancreatography (ERCP) is indicated for gallstone-induced acute cholangitis and pancreatitis. The technique and optimal timing of ERCP depend on the disease state, its severity, anatomy, patient background, and the institutional situation. Endoscopic transpapillary biliary drainage within 24 h is recommended for moderate to severe acute cholangitis. Read More

J Transl Int Med 2022 Mar 2;10(1):18-27. Epub 2022 Apr 2.

Department of Radiology, Changhai Hospital, The Naval Medical University, Shanghai 200433, China.

The basic pancreatic lesions include location, size, shape, number, capsule, calcification/calculi, hemorrhage, cystic degeneration, fibrosis, pancreatic duct alterations, and microvessel. One or more basic lesions form a kind of pancreatic disease. As recognizing the characteristic imaging features of pancreatic basic lesions and their relationships with pathology aids in differentiating the variety of pancreatic diseases. Read More

J Gastrointestin Liver Dis 2022 Jun 12;31(2):162. Epub 2022 Jun 12.

Gastroenterology Department, Hospital de Braga, Braga, Portugal.

Acad Forensic Pathol 2022 Mar 2;12(1):31-38. Epub 2022 Feb 2.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused the COVID-19 pandemic raised important questions about workplace exposures to the virus, including postmortem exposures. The complexity of COVID-19 disease and its numerous unanticipated complications made autopsy even more vital in determining the pathophysiology of the disease. Performing traditional autopsy, however, carries risk of exposure. Read More

Hepatobiliary Surg Nutr 2022 Jun;11(3):355-362

Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Background: Type 1 autoimmune pancreatitis (AIP) is the pancreatic manifestation of IgG4-related disease. However, this benign disease can result in the peripancreatic vascular involvement (PVI) on occasion, which increases the difficulty of diagnosis and treatment of this clinical entity as well as for differentiating it from pancreatic malignancies.

Methods: We retrospectively reviewed the information on demographics, clinical presentation, laboratory, imaging and endoscopic findings of 101 hospitalized patients with type 1 AIP treated in our department. Read More

Nihon Shokakibyo Gakkai Zasshi 2022 ;119(6):573-579

Department of Gastroenterology, Shiga University of Medical Science.

A 44-year-old man with a history of chronic alcoholic pancreatitis and Crohn's disease presented with abdominal pain. Computed tomography revealed pancreatic calculi in the head of the pancreas and a dilated pancreatic duct. The patient was diagnosed with an acute exacerbation of chronic pancreatitis due to the impact of pancreatic calculi on the main pancreatic duct. Read More

J Clin Exp Hepatol 2022 May-Jun;12(3):1012-1016. Epub 2021 Nov 16.

Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

IgG4-related diseases are rare multisystem disorders involving salivary glands, retroperitoneum, pancreas, biliary tract, and liver. Isolated biliary strictures and gall bladder involvement are rare in such patients, and presentation with cholangitis and weight loss can misguide the diagnosis toward malignancy. Here, we report an interesting case of IgG4-related biliary stricture with gall bladder involvement, presented with cholangitis and weight loss. Read More

Thromb Res 2022 May 27;216:1-7. Epub 2022 May 27.

Division of Hematology and Oncology, Oregon Health & Science University, Portland, OR, United States of America; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States of America.

Introduction: Splanchnic vein thrombosis (SVT) occurs in a heterogenous group of patients secondary to a variety of risk factors including liver disease. Minimal data regarding natural history and outcomes of SVT exists to inform management decisions. As such, there is equipoise regarding the utility of anticoagulation in cirrhotic patients with SVT. Read More

Int J Surg Case Rep 2022 May 1;94:107127. Epub 2022 May 1.

Department of Surgery, RIMS, Ranchi.

Introduction: Among a plethora of causes of acute abdomen, spontaneous common bile duct perforation (SCBDP) resulting in biliary peritonitis is almost never envisaged. Since the term SCBDP is often misconstrued as absence of an identifiable cause of perforation, 'nontraumatic perforation of CBD' is also in parlance to exclude relatively common causes such as trauma and iatrogenic injuries. In adults, choledochal cyst, cholangitis, infection, pancreatitis, pancreatobiliary maljunction have been identified as causes of perforation, however, choledocholithiasis remains the most common cause associated with spontaneous perforation of extra hepatic bile duct. Read More

Ulus Travma Acil Cerrahi Derg 2022 Jun;28(6):769-775

Department of Internal Medicine, Division of Gastroenterology, Van Training and Research Hospital, Van-Turkey.

Background: While a life-threatening course is observed in 2-3% of patients with acute pancreatitis (AP), mortality can be up to 50% in severe AP. In our study, we research relationship between calcium level and Modified Balthazar (MB) score.

Methods: 354 patients who were followed up with a diagnosis of AP between 2013 and 2019 were included in our study. Read More

Endocrinol Diabetes Metab Case Rep 2022 Jun 1;2022. Epub 2022 Jun 1.

Department of Medicine DIMED, University of Padova, Padova, Italy.

Summary: A 61-year-old man went to the Emergency Department with left upper abdominal quadrant pain and low-grade fever, as well as a loss of weight (3 kg in 6 weeks). A solid-cystic lesion in the left adrenal lodge was discovered by abdominal ultrasonography. A slight increase in the serum amylase with normal lipase was observed, but there were no signs or symptoms of pancreatitis. Read More

Langenbecks Arch Surg 2022 May 31. Epub 2022 May 31.

General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.

Purpose: Several interventional procedures are available to treat moderate-to-critical acute pancreatitis (AP) in its late phase. The ongoing debate on these options, together with the scarcity of reported quality of life (QoL) information in the Literature, prompted us to conduct a review of our experience.

Methods: All the patients treated at our referral Center for moderate-to-critical AP according to Determinant-Based Classification (DBC) were retrospectively reviewed. Read More

J Magn Reson Imaging 2022 May 30. Epub 2022 May 30.

College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.

Background: Pancreatic fat accumulation may cause or aggravate the process of acute pancreatitis, β-cell dysfunction, T2DM disease, and even be associated with pancreatic tumors. The pathophysiology of fatty pancreas remains overlooked and lacks effective imaging diagnostics.

Purpose: To automatically measure the distribution of pancreatic fat deposition on Dixon MRI in multicenter/population datasets using nnU-Net models. Read More

J Int Med Res 2022 May;50(5):3000605221100748

Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China.

Whether pancreatic extracorporeal shock wave lithotripsy (ESWL) is safe for patients with autosomal dominant polycystic kidney disease (ADPKD) is unclear. A woman in her early 30s was admitted to our hospital because of intermittent upper abdominal pain and recurrent pancreatitis. The imaging results confirmed the diagnosis of pancreatic stones and ADPKD. Read More

Wiad Lek 2022 ;75(4 pt 2):1039-1042

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

The given paper describes a case of treating adenocarcinoma of the papilla of Vater diagnosed as the cause after an episode of acute pancreatitis. The etiology of aсute pancreatitis was considered idiopathic until the onset of complaints caused by tumor growth. The volume of radical surgery has changed intraoperatively due to the detection of infected limited necrotic clusters, didn't diagnosed both laboratory and instrumentally. Read More

Cancers (Basel) 2022 May 21;14(10). Epub 2022 May 21.

School of Clinical Medicine, Faculty of Medicine & Health, UNSW, Sydney, NSW 2052, Australia.

Pancreatic cancer, one of the most lethal malignancies, is increasing in incidence. While survival rates for many cancers have improved dramatically over the last 20 years, people with pancreatic cancer have persistently poor outcomes. Potential cure for pancreatic cancer involves surgical resection and adjuvant therapy. Read More

J Pak Med Assoc 2022 Apr;72(4):752-754

Department of General Surgery, Brighton and Sussex University Hospital, Brighton, UK.

Splanchnic vein thromboses are well recognized vascular complications of acute as well as chronic pancreatitis. Extra splanchnic thromboses have rarely been reported. One such case of a 41-year-old Pakistani male patient who developed acute alcoholic pancreatitis is presented. Read More

Dig Liver Dis 2022 Jul 23;54(7):994-995. Epub 2022 May 23.

Department of Radiology and the Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Korea. Electronic address:

J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221099269

SUNY Upstate Medical University, Syracuse, NY, USA.

Chronic pancreatitis presents with epigastric abdominal pain, nausea, vomiting, and weight loss. Acute pancreatitis can also present with a pleural effusion which is typically left-sided, mild in nature, and self-limiting. However, recurrent bouts of pancreatitis may lead to a pancreaticopleural fistula (PPF) with a large, rapidly recurring, unilateral pleural effusion. Read More