4,446 results match your criteria Acute Pancreatitis Imaging


Acute pancreatitis with abdominal bloating and distension, normal lipase and amylase: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15138

Departments of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, PR China and Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, PR China.

Rationale: Acute pancreatitis is an inflammatory disorder of the pancreas, and its correct diagnosis is an area of interest for clinicians. In accordance with the revised Atlanta classification, acute pancreatitis can be diagnosed if at least 2 of the following 3 criteria are fulfilled: abdominal pain; serum lipase (or amylase) activity at least 3 times the upper limit of normal; or characteristic findings of acute pancreatitis on contrast-enhanced computed tomography (CT) or, less often, magnetic resonance imaging or transabdominal ultrasonography. Diagnostic imaging is essential in patients with no or slight enzyme elevation. Read More

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http://dx.doi.org/10.1097/MD.0000000000015138DOI Listing

Quantitative pancreatic MRI: a pathology-based review.

Br J Radiol 2019 Apr 14:20180941. Epub 2019 Apr 14.

1 University College London (UCL) Centre for Medical Imaging, Division of Medicine, UCL , London , UK.

MRI plays an important role in the clinical management of pancreatic disorders and interpretation is reliant on qualitative assessment of anatomy. Conventional sequences capturing pancreatic structure can however be adapted to yield quantitative measures which provide more diagnostic information, with a view to increasing diagnostic accuracy, improving patient stratification, providing robust non-invasive outcome measures for therapeutic trials and ultimately personalizing patient care. In this review, we evaluate the use of established techniques such as secretin-enhanced MR cholangiopancreatography, diffusion-weighted imaging, T , T * and fat fraction mapping, but also more experimental methods such as MR elastography and arterial spin labelling, and their application to the assessment of diffuse pancreatic disease (including chronic, acute and autoimmune pancreatitis/IgG4 disease, metabolic disease and iron deposition disorders) and cystic/solid focal pancreatic masses. Read More

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http://dx.doi.org/10.1259/bjr.20180941DOI Listing

Pancreas shrinkage following recurrent acute pancreatitis: an MRI study.

Eur Radiol 2019 Apr 12. Epub 2019 Apr 12.

School of Medicine, University of Auckland, Auckland, New Zealand.

Objective: Transition from the first attack of acute pancreatitis (AP) to chronic pancreatitis (CP) via recurrent AP is common. Total pancreas volume (TPV) and pancreas diameters are often reduced in advanced CP but have never been studied after AP. The objective of this study was to investigate pancreas size after clinical resolution of AP and its association with the number of AP attacks. Read More

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http://dx.doi.org/10.1007/s00330-019-06126-7DOI Listing

Intra peritoneal abdominal fat area measured from computed tomography is an independent factor of severe acute pancreatitis.

Diagn Interv Imaging 2019 Apr 8. Epub 2019 Apr 8.

Department of Radiology, CHU de Poitiers, 86000 Poitiers, France. Electronic address:

Purpose: The purpose of this study was to search for a possible relationship between acute pancreatitis (AP) severity and visceral fat (VF) surface on contrast-enhanced computed tomography (CECT).

Material And Method: A total of 112 patients with AP who underwent CECT within 2 to 3 days after the beginning of AP were included. There were 68 mean and 44 women, with a mean age of 56. Read More

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http://dx.doi.org/10.1016/j.diii.2019.03.008DOI Listing

Type 2 Autoimmune Pancreatitis (Idiopathic Duct-Centric Pancreatitis) Highlighting Patients Presenting as Clinical Acute Pancreatitis: A SingleCenter Experience.

Gut Liver 2019 Apr 17. Epub 2019 Apr 17.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background/aims: : Type 2 autoimmune pancreatitis (AIP) has been considered extremely rare in East Asia. This study aimed to clarify the prevalence, clinical characteristics and radiological findings of type 2 AIP highlighting patients presenting as acute pancreatitis in a single center.

Methods: : Type 2 AIP patients were classified according to International Consensus Diagnostic Criteria. Read More

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http://dx.doi.org/10.5009/gnl18429DOI Listing
April 2019
1 Read

[Pancreatic Mass or Cyst? Diagnostic Dilemma].

Dig Dis 2019 Apr 8:1-4. Epub 2019 Apr 8.

Division of Gastroenterology and Hepatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

A santorinicele is a rare anomaly defined as focal cystic dilation of the terminal portion of the dorsal pancreatic duct at the minor papilla. Importantly this anomaly has been suggested as a possible cause of relative stenosis of the minor papilla. This anomaly has been associated with pancreatic divisum and recurrent acute pancreatitis. Read More

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http://dx.doi.org/10.1159/000497448DOI Listing
April 2019
1 Read

Gastric Heterotopic Pancreas Presenting as Abdominal Pain with Acute and Chronic Pancreatitis in the Resected Specimen.

Case Rep Gastrointest Med 2019 6;2019:2021712. Epub 2019 Mar 6.

Warren Alpert Medical School, Brown University, Providence, RI, USA.

Heterotopic pancreas, also known as ectopic pancreas, is pancreatic tissue located outside the pancreatic parenchyma without vascular or ductal communication with the gland. Ectopic pancreas is rarely symptomatic, typically detected incidentally at surgery or autopsy. Eighty-five to 90% are in the upper GI tract, especially the gastric antrum. Read More

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http://dx.doi.org/10.1155/2019/2021712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431401PMC
March 2019
2 Reads

Chronic Asymptomatic Pancreatic Hyperenzymemia: A Long-term Follow-up.

Pancreas 2019 04;48(4):544-547

Department of Radiology, Pancreas Institute, University of Verona, Verona, Italy.

Objectives: Chronic asymptomatic pancreatic hyperenzymemia (CAPH) was described as a benign disease. However, we already described clinically relevant findings requiring surgery or follow-up in half of the subjects. The aim of this study was to evaluate the long-term outcome of CAPH in terms of symptoms and evolution toward chronic pancreatitis. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001272DOI Listing
April 2019
1 Read

Retrospective Matched-Cohort Analysis of Acute Pancreatitis Induced by 5-Aminosalicylic Acid-Derived Drugs.

Pancreas 2019 04;48(4):488-495

Division of Translational Medicine, First Department of Medicine, University of Pécs, Medical School.

Objectives: This study aimed to compare the clinical course of 5-aminosalicylic acid-derived, drug-induced acute pancreatitis (5-ASA-DIAP) to acute pancreatitis (AP) caused by other etiologies.

Methods: A cohort of patients with 5-ASA-DIAP was established through literature search. As a control AP (CAP) group, a cohort was generated from a registry. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001297DOI Listing
April 2019
1 Read

Hepatobiliary and pancreatic manifestations in inflammatory bowel diseases: a referral center study.

BMC Gastroenterol 2019 Apr 3;19(1):48. Epub 2019 Apr 3.

Department of Gastroenterology and Hepatology, Medical school and University of Ioannina, Ioannina, Greece.

Background: Hepatobiliary and pancreatic manifestations have been reported in patients with Crohn's disease or ulcerative colitis. Our aim was to describe the prevalence of hepatobiliary and pancreatic manifestations in inflammatory bowel disease and their association with the disease itself and the medications used.

Methods: Data were retrospectively extracted from the clinical records of patients followed up at our tertiary IBD referral Center. Read More

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http://dx.doi.org/10.1186/s12876-019-0967-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446300PMC
April 2019
2 Reads

Intra-pancreatic fat deposition and visceral fat volume are associated with the presence of diabetes after acute pancreatitis.

Am J Physiol Gastrointest Liver Physiol 2019 Mar 28. Epub 2019 Mar 28.

University of Auckland, New Zealand.

Ectopic fat and abdominal adiposity phenotypes have never been investigated holistically in individuals after acute pancreatitis (AP). The aim of the study was to investigate phenotypic differences in ectopic fat and abdominal fat between individuals after AP (with and without diabetes) and to determine the role of pancreatitis-related factors. Eighty-four individuals were studied cross-sectionally in, on average, 21 months since last episode of AP and were categorized into 'diabetes' and 'no diabetes' groups. Read More

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http://dx.doi.org/10.1152/ajpgi.00385.2018DOI Listing

A pancreatic hemorrhagic pseudocyst with pseudoaneurysm and the role of doppler ultrasonography: a case report.

Rev Assoc Med Bras (1992) 2019 Feb;65(2):123-126

Department of Radiology, Soonchunhyang University Seoul Hospital, Yongsan-gu, Seoul, Korea.

Hemorrhagic pseudocysts with pseudoaneurysms are a rare and fatal complication of chronic pancreatitis due to the erosion of pancreatic to peripancreatic arteries. The timing of the rupture cannot be accurately predicted, but prompt diagnosis and management are essential to prevent further bleeding. We describe the case of a 68-year-old man who presented acute epigastric pain and anemia and had a history of chronic pancreatitis with a pseudocyst. Read More

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http://dx.doi.org/10.1590/1806-9282.65.2.123DOI Listing
February 2019
1 Read
0.915 Impact Factor

Dynamic Contrast-Enhanced MRI for Measuring Pancreatic Perfusion in Acute Pancreatitis: A Preliminary Study.

Acad Radiol 2019 Mar 15. Epub 2019 Mar 15.

Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, No.234, Fujiang Road, Shunqing District, Nanchong 637000, China. Electronic address:

Rationale And Objectives: To assess the characteristics of pancreatic perfusion in normal pancreas and acute pancreatitis (AP) by using dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI).

Method And Materials: Eighty-One AP patients and 26 normal subjects underwent DCE-MRI. The Omitk-Tool was used to analyze perfusion parameters such as K, V and AUC. Read More

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http://dx.doi.org/10.1016/j.acra.2019.02.007DOI Listing

Rare complication of milk-alkali ingestion: severe pancreatitis and acute kidney injury in a chronic hypocalcaemic patient with DiGeorge's syndrome.

BMJ Case Rep 2019 Mar 15;12(3). Epub 2019 Mar 15.

Department of Internal Medicine, St Vincent Charity Medical Center, Cleveland, Ohio, USA.

Injudicious use of over-the-counter calcium supplements has resulted in increased incidences of hypercalcaemia and related complications. We present a case of acute pancreatitis in a chronic hypocalcaemic patient of DiGeorge's syndrome. The patient came into the ED with sepsis syndrome, right upper quadrant and epigastric pain and no obvious source of infection. Read More

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http://dx.doi.org/10.1136/bcr-2018-226761DOI Listing
March 2019
1 Read

Urinalysis and Urinary GGT-to-Urinary Creatinine Ratio in Dogs with Acute Pancreatitis.

Vet Sci 2019 Mar 13;6(1). Epub 2019 Mar 13.

Department of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56121 Pisa, Italy.

In acute pancreatitis (AP), kidney injury (KI) can occur. Urinalysis and some urinary biomarkers have been proposed as prognostic tools in human AP. The aim of the study was to evaluate urinalysis and urinary GGT-to-urinary creatinine (uGGT/uCr) in canine AP and their association with possible outcomes. Read More

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http://dx.doi.org/10.3390/vetsci6010027DOI Listing
March 2019
1 Read

Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness cost.

World J Gastroenterol 2019 Mar;25(9):1080-1087

Department of Gastroenterology, Advocate Christ Medical Center, Oak Lawn, IL 60453, United States.

Background: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. Read More

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http://dx.doi.org/10.3748/wjg.v25.i9.1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406186PMC
March 2019
2 Reads

Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature.

Am J Case Rep 2019 Mar 13;20:330-334. Epub 2019 Mar 13.

Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA.

BACKGROUND Beriberi due to thiamine (vitamin B1) deficiency has two clinical presentations. Patients with dry beriberi present with neuropathy, and patients with wet beriberi present with heart failure, with or without neuropathy. Dry beriberi can mimic the most common form of Guillain-Barre syndrome (GBS), an acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Read More

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http://dx.doi.org/10.12659/AJCR.914051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429982PMC
March 2019
18 Reads

Significance of radiology in the diagnosis and management of ruptured left gastric artery aneurysm associated with acute pancreatitis: Case report.

Medicine (Baltimore) 2019 Mar;98(10):e14824

Department of Radiology, The First Affiliated Hospital of Dali University, Dali, Yunnan, People's Republic of China.

Rationale: Left gastric artery aneurysms are very rare which progresses into hemorrhagic shock and diagnosis is very challenging particularly in patients with acute pancreatitis and cholecystitis whose vitals become unstable suddenly.

Patient Concerns: A 72-year-old female has presented with severe progressing abdominal pain was treated with total parenteral nutrition for acute pancreatitis based on preliminary work up, but suddenly became unstable with dropping vitals over the ensuing 48 hours. Physical examination has a positive Murphy sign and appeared lethargic. Read More

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http://dx.doi.org/10.1097/MD.0000000000014824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417524PMC
March 2019
5 Reads

Assessment of acute obstructive pancreatitis by magnetic resonance imaging: Predicting the occurrence of pancreatic fistula following pancreatoduodenectomy.

Mol Clin Oncol 2019 Mar 9;10(3):371-376. Epub 2019 Jan 9.

Department of Radiology, Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.

The aim of the present study was to assess the effect of preoperative acute obstructive pancreatitis on the risk of the occurrence of pancreatic fistula (PF) following pancreaticoduodenectomy. A total of 22 patients who developed postoperative PF were carefully matched with 22 control patients without PF according to demographic data, pancreatic pathology, presenting symptoms and other surgery-associated parameters. These parameters were compared between these two groups. Read More

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http://dx.doi.org/10.3892/mco.2019.1799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388463PMC

Thoracic complications of pancreatitis.

JGH Open 2019 Feb 22;3(1):71-79. Epub 2018 Oct 22.

Department of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.

Acute pancreatitis in its severe form may lead to systemic inflammatory response syndrome and multisystem organ dysfunction. Acute lung injury is an important cause of mortality in the setting of severe acute pancreatitis. Besides lung involvement, acute and chronic pancreatitis may also lead to the involvement of other thoracic compartments, including mediastinum, pleura, and vascular structures. Read More

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http://dx.doi.org/10.1002/jgh3.12099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386740PMC
February 2019
2 Reads

Formation of Pancreatoduodenal Fistula in Intraductal Papillary Mucinous Neoplasm of the Pancreas Decreased the Frequency of Recurrent Pancreatitis.

Gastroenterology Res 2019 Feb 26;12(1):43-47. Epub 2019 Feb 26.

Saint Louis University School of Medicine, St. Louis, MO, USA.

Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are characterized by proliferation of mucin-secreting cells in the main pancreatic duct (PD) or its branches. The secreted thick mucin usually leads to PD obstruction and dilation. A common complication of IPMN is recurrent acute pancreatitis secondary to poor pancreatic fluid drainage, and rarely, pancreatobiliary and pancreatointestinal fistulae. Read More

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http://dx.doi.org/10.14740/gr1140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396797PMC
February 2019
2 Reads

Establishing a model to measure and predict the quality of gastrointestinal endoscopy.

World J Gastroenterol 2019 Feb;25(8):1024-1030

Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.

Background: Tens of millions of gastrointestinal endoscopic procedures are performed every year in China, but the quality varies significantly and related factors are complex. Individual endoscopist- and endoscopy division-related factors may be useful to establish a model to measure and predict the quality of endoscopy.

Aim: To establish a model to measure and predict the quality of gastrointestinal endoscopic procedures in mainland China. Read More

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https://www.wjgnet.com/1007-9327/full/v25/i8/1024.htm
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http://dx.doi.org/10.3748/wjg.v25.i8.1024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397728PMC
February 2019
3 Reads

[Treatment of acute necrotizing pancreatitis].

Internist (Berl) 2019 Mar;60(3):226-234

Medizinische Klinik und Poliklinik II, Universitätsklinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

Acute pancreatitis (AP) has an annual incidence of 30-45 per 100,000 inhabitants. In Germany approximately one third of the cases are of biliary or alcoholic origin. The diagnosis is based on the typical epigastric pain with radiation and a threefold increase of lipase or amylase in serum. Read More

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http://dx.doi.org/10.1007/s00108-019-0558-yDOI Listing
March 2019
1 Read

Etiology and clinical characteristics of pediatric acute pancreatitis in Saudi Arabia: a 20-year experience from a single tertiary center.

Int J Pediatr Adolesc Med 2018 Mar 24;5(1):13-17. Epub 2018 Feb 24.

King Abdullah Specialist Children Hospital, Pediatric Gastroenterology, Riyadh, Saudi Arabia.

Background: Cases of acute pancreatitis (AP) have increased among pediatric populations worldwide; however, the natural course of this condition in Saudi Arabia was unknown.

Aim: To report the characteristics as well as outcomes of pediatric AP.

Patients And Methods: A retrospective chart review study was conducted to include acute pancreatitis in patients ≤ 19 years. Read More

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http://dx.doi.org/10.1016/j.ijpam.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363251PMC
March 2018
1 Read

An overview of walled-off pancreatic necrosis for clinicians.

Expert Rev Gastroenterol Hepatol 2019 Apr 8;13(4):331-343. Epub 2019 Feb 8.

a Department of Gastroenterology , Post Graduate Institute of Medical Education and Research (PGIMER) , Chandigarh , India.

Introduction: Walled of pancreatic necrosis (WOPN) is a new term coined for encapsulated fluid collection developing after acute necrotising pancreatitis (ANP). It is a heterogeneous collection containing varying amount of liquid as well as solid necrotic material. The literature on its natural history as well as appropriate management is gradually expanding thereby improving treatment outcomes of this enigmatic disease. Read More

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http://dx.doi.org/10.1080/17474124.2019.1574568DOI Listing

Clinical Profile and Outcome of Parathyroid Adenoma-Associated Pancreatitis.

Saudi J Med Med Sci 2018 May-Aug;6(2):95-99. Epub 2018 Apr 16.

Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.

Background: Primary hyperparathyroidism due to parathyroid adenoma presenting with pancreatitis as the initial manifestation is rare. The causal relationship between pancreatitis and primary hyperparathyroidism is debatable.

Objective: To study the clinical and biochemical profile of patients with parathyroid adenoma-associated pancreatitis as well as the outcome following parathyroidectomy. Read More

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http://dx.doi.org/10.4103/sjmms.sjmms_80_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196711PMC
April 2018
1 Read

Frequency & predictors of pancreatitis in symptomatic primary hyperparathyroidism.

Indian J Med Res 2018 Dec;148(6):721-727

Department of Endocrinology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Background & Objectives: The frequency and predictors of pancreatitis in primary hyperparathyroidism (PHPT) are not well understood. The objective of the present study was to evaluate the frequency of pancreatitis in patients with PHPT and its association with clinical and biochemical parameters of the disease.

Methods: In this retrospective study all consecutive patients with PHPT registered in the PHPT registry (www. Read More

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http://dx.doi.org/10.4103/ijmr.IJMR_353_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396558PMC
December 2018
6 Reads
1.661 Impact Factor

Rationally designed pure-inorganic upconversion nanoprobes for ultra-highly selective hydrogen sulfide imaging and elimination .

Chem Sci 2019 Jan 12;10(4):1193-1200. Epub 2018 Nov 12.

Department of Chemistry , Capital Normal University , Beijing 100048 , China . Email: ; Tel: +86-010-68902491.

Lung injury is a hydrogen sulfide (HS)-associated complication with high mortality in acute pancreatitis (AP) cases. Herein, we used Prussian Blue (PB) as a HS-responsive acceptor to develop a novel pure-inorganic upconversion nanoprobe for detecting and eliminating HS, which can be used for diagnosing AP and alleviating lung injury. Upconversion nanoprobes with 5 nm PB shells were optimized to achieve outstanding HS detection capacity (linear range: 0-150 μM, LOD: 50 nM), which met the serum HS range, and thus were feasible for imaging HS . Read More

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http://dx.doi.org/10.1039/c8sc04464cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349023PMC
January 2019
1 Read

Acute Pancreatitis after Colonoscopy: A Case Presentation and Literature Review.

Case Rep Gastrointest Med 2019 15;2019:4587371. Epub 2019 Jan 15.

Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA, USA.

We report a case of acute pancreatitis after an elective screening colonoscopy. A 51-year-old male with a left ventricular assist device for end-stage nonischemic cardiomyopathy and a family history of colorectal cancer was admitted for an expedited heart transplant evaluation. He underwent screening colonoscopy during this admission which was technically uncomplicated apart from requiring slight maneuvering at the splenic flexure. Read More

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http://dx.doi.org/10.1155/2019/4587371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350525PMC
January 2019
2 Reads

Role of Diagnostic Endoscopic Ultrasound in Idiopathic Acute Pancreatitis and Acute Recurrent Pancreatitis in Children.

Pancreas 2019 03;48(3):350-355

From the Division of Pediatric Gastroenterology, Department of Gastroenterology.

Objectives: Endoscopic ultrasound (EUS) is a minimally invasive pancreatic imaging modality. We evaluated children with idiopathic acute pancreatitis (IAP) and acute recurrent pancreatitis (ARP) for changes of chronicity (Rosemont criteria) and biliary risk factors. Diagnostic yield of simultaneously performed transabdominal ultrasonography (TUS) was compared with EUS. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001243DOI Listing
March 2019
6 Reads

[Fulminant type 1 diabetes mellitus following acute pancreatitis and hypoglycemia with sequential imaging of the pancreas using computed tomography: a case report].

Nihon Shokakibyo Gakkai Zasshi 2019;116(2):161-167

Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University.

We herein report a rare case of fulminant type 1 diabetes mellitus (FT1DM) following acute pancreatitis and hypoglycemia, in which the pancreas was evaluated by serial computed tomography (CT). A 30-year-old male presented to a local hospital with a two-day history of abdominal pain and was diagnosed with acute pancreatitis based on elevated serum amylase and peripancreatic fluid collection on CT images. The patient developed sudden hypoglycemia (plasma glucose, 45mg/dL;serum C-peptide, 3. Read More

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http://dx.doi.org/10.11405/nisshoshi.116.161DOI Listing
January 2019
1 Read

Venous Thromboembolism in Necrotizing Pancreatitis: an Underappreciated Risk.

J Gastrointest Surg 2019 Feb 7. Epub 2019 Feb 7.

Department of Surgery, Indiana University School of Medicine, 545 Barnhill Drive EH 519, Indianapolis, IN, 46202, USA.

Background: Necrotizing pancreatitis (NP) is a severe systemic inflammatory process. We have observed a high incidence of venous thromboembolism (VTE) in NP patients. However, remarkably few data exist to document the true incidence of VTE-including splanchnic vein thrombosis (SVT), extremity deep venous thrombosis (eDVT), and pulmonary embolism (PE)-in NP. Read More

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http://dx.doi.org/10.1007/s11605-019-04124-0DOI Listing
February 2019
1 Read

Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine.

Front Immunol 2019 24;10:28. Epub 2019 Jan 24.

Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States.

Neutrophil extracellular traps (NETs) are generated when activated neutrophils, driven by PAD4, release their DNA, histones, HMGB1, and other intracellular granule components. NETs play a role in acute pancreatitis, worsening pancreatic inflammation, and promoting pancreatic duct obstruction. The autophagy inhibitor chloroquine (CQ) inhibits NET formation; therefore, we investigated the impact of CQ mediated NET inhibition in murine models of pancreatitis and human correlative studies. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353831PMC
January 2019
8 Reads

Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury.

J Immunother Cancer 2019 Feb 6;7(1):31. Epub 2019 Feb 6.

Departments of Gastroenterology, Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Immune checkpoint inhibitor (ICI)-induced pancreatic injury (ICIPI) is not well documented in the literature. We aimed to describe the clinical characteristics and outcomes of patients who developed ICIPI.

Methods: We reviewed the medical records of consecutive patients who had a confirmed diagnosis of ICIPI (Common Terminology Criteria for Adverse Events grade ≥ 3 lipase elevation with or without clinical symptoms) from April 2011 through April 2018. Read More

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http://dx.doi.org/10.1186/s40425-019-0502-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364483PMC
February 2019

Imaging of Gastrointestinal and Abdominal Emergencies in Binge Drinking.

Can Assoc Radiol J 2019 Feb;70(1):52-61

Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore.

Excess alcohol consumption is a leading cause of preventable morbidity and mortality globally. The pattern of consumption of alcoholic beverages has changed in our society in the recent past, with binge drinking becoming more and more common, especially among young adults. Abdominal pain following alcohol consumption can be secondary to a wide range of pathologies, the treatment algorithm of which can range from medical supportive treatment to more invasive life-saving procedures such as transarterial embolization and emergency laparotomy. Read More

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http://dx.doi.org/10.1016/j.carj.2018.10.009DOI Listing
February 2019
2 Reads

Advanced endoscopic interventions on the pancreas and pancreatic ductal system: a primer for radiologists.

Insights Imaging 2019 Jan 28;10(1). Epub 2019 Jan 28.

Digestive Endoscopy, "Luigi Sacco" University Hospital, Via G.B. Grassi 74, 20157, Milan, Italy.

In recent years, technological advancements including endoscopic ultrasound (EUS) guidance and availability of specifically designed stents further expanded the indications and possibilities of interventional endoscopy. Although technically demanding and associated with non-negligible morbidity, advanced pancreatic endoscopic techniques now provide an effective minimally invasive treatment for complications of acute and chronic pancreatitis.Aiming to provide radiologists with an adequate familiarity, this pictorial essay reviews the indications, techniques, results and pre- and post-procedural cross-sectional imaging appearances of advanced endoscopic interventions on the pancreas and pancreatic ductal system. Read More

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https://insightsimaging.springeropen.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s13244-019-0689-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352387PMC
January 2019
9 Reads

[Acute abdomen - gastrointestinal causes].

Radiologe 2019 Feb;59(2):114-125

Klinik und Poliklinik für Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Marchioninistr. 15, 81377, München, Deutschland.

Clinical/methodical Issue: Diagnostic imaging plays a crucial role in the assessment and stratification of pathologic conditions causing acute abdomen. This report provides information on etiology, clinical manifestations and therapeutic options for six common diseases resulting in acute abdomen-appendicitis, cholecystitis, bowel obstruction, diverticulitis, acute pancreatitis, and viscus perforation.

Performance: Besides initial ultrasound, CT scans often represent the imaging gold standard for the diagnostic evaluation of acute abdomen. Read More

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http://dx.doi.org/10.1007/s00117-019-0491-zDOI Listing
February 2019
1 Read

3D MR elastography of the pancreas in children.

Abdom Radiol (NY) 2019 Jan 25. Epub 2019 Jan 25.

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Purpose: Early diagnosis of chronic pancreatitis (CP) remains elusive. Preliminary data suggest that MR elastography (MRE) may have diagnostic value in the identification of CP. We sought to measure pancreas stiffness by MRE in healthy children and to compare measured values to stiffness values in pediatric patients with acute recurrent pancreatitis (ARP) or CP. Read More

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http://dx.doi.org/10.1007/s00261-019-01903-wDOI Listing
January 2019
3 Reads

Clinical spectrum of adult patients with annular pancreas: Findings from a large single institution cohort.

Pancreatology 2019 Mar 3;19(2):290-295. Epub 2019 Jan 3.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Background And Aims: Annular pancreas (AnnP) is a rare congenital abnormality that results from the presence of a complete or partial ring of pancreatic tissue surrounding the descending portion of the duodenum. While the clinical presentation and management of AnnP in neonates and infants has been well described, the complete spectrum of clinical presentation of AP in adults is not very clear. We aimed to describe the clinical spectrum of presentation and management of adult patients with AnnP. Read More

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http://dx.doi.org/10.1016/j.pan.2018.12.009DOI Listing
March 2019
11 Reads

Against the Odds: A Novel Technique to Perform Cholangiography from a Percutaneous Approach through the Cystic Duct.

Cureus 2018 Nov 12;10(11):e3577. Epub 2018 Nov 12.

Interventional Radiology, University of Florida College of Medicine, Jacksonville, USA.

Percutaneous cholangiography is typically performed via a transhepatic approach and is reserved for patients with contraindications to traditional cholangiogram imaging modalities. For those with suspected cholelithiasis or choledocholithiasis who cannot undergo magnetic resonance imaging for diagnosis, percutaneous cholecystostomy with cholangiogram is a viable option. Endoscopic retrograde cholangiopancreatography may also be precluded due to anatomic or obstructive limitations, in which case, percutaneous transhepatic cholangiography (PTC) may be indicated for diagnosis. Read More

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http://dx.doi.org/10.7759/cureus.3577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333255PMC
November 2018
3 Reads

Acute-phase endovascular management of an uncommon bleeding peripancreatic pseudoaneurysm.

J Radiol Case Rep 2018 May 31;12(5):12-18. Epub 2018 May 31.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, via Vetoio, L'Aquila, Italy.

Pancreatic pseudoaneurysms represent relatively rare but potentially lethal complications of acute or chronic pancreatitis, involving several visceral arteries. Due to their intrinsic instability and subsequent high risk of massive bleeding, these lesions require prompt treatment, regardless of the size of the pseudoaneurysm. First option of treatment is today represented by transcatheter embolization; this treatment, in fact, shows higher rates of clinical and technical success and lower recurrence rates than conventional surgery. Read More

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http://www.radiologycases.com/index.php/radiologycases/artic
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http://dx.doi.org/10.3941/jrcr.v12i5.3285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310209PMC
May 2018
8 Reads

Annular Pancreas in an Adult Presenting with Acute Pancreatitis.

J Radiol Case Rep 2018 Oct 31;12(10):11-16. Epub 2018 Oct 31.

Department of Radiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Annular pancreas is a rare congenital condition in which tissue from the head of the pancreas partially or completely surrounds the second part of the duodenum. This condition has a variable clinical presentation in adults and children. Radiologists should be aware of the imaging findings in adults as an annular pancreas can be overlooked or misdiagnosed in this patient population. Read More

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http://dx.doi.org/10.3941/jrcr.v12i10.3461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312117PMC
October 2018
1 Read

The Utility of Endoscopic Ultrasound in Patients with Isolated Elevations in Serum Amylase and/or Lipase.

Clin Endosc 2019 Mar 16;52(2):175-181. Epub 2019 Jan 16.

Division of Digestive and Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.

Background/aims: The aim of this study was to describe the diagnostic yield of endoscopic ultrasound (EUS) in patients with isolated elevated levels of amylase and/or lipase.

Methods: A retrospective chart review was conducted at a large academic medical center from 2000 to 2016. Patients were selected based on having elevated amylase, lipase, or both, but without a diagnosis of pancreatitis or known pancreatobiliary disease. Read More

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http://dx.doi.org/10.5946/ce.2018.110DOI Listing
March 2019
5 Reads

Revised Atlanta classification for CT pancreatic and peripancreatic collections in the first month of acute pancreatitis: interobserver agreement.

Eur Radiol 2019 May 10;29(5):2302-2310. Epub 2019 Jan 10.

Department of Radiology, Hôpital Saint-Joseph, 185 Rue Raymond Losserand, 75014, Paris, France.

Purpose: To assess interobserver agreement when using the revised Atlanta classification (RAC) to categorize pancreatic and peripancreatic collections during the first month of acute pancreatitis (AP), and to correlate type of collection to outcome.

Material And Methods: This retrospective study of 115 consecutive patients admitted for 123 AP episodes, 178 CTs performed within the first month showed peripancreatic abnormalities. Each AP episode was classified as mild, moderately severe, or severe based on the RAC. Read More

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http://dx.doi.org/10.1007/s00330-018-5906-0DOI Listing
May 2019
10 Reads

Sinistral Portal Hypertension in Acute Pancreatitis: A Magnetic Resonance Imaging Study.

Pancreas 2019 02;48(2):187-192

Radiology Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Objective: The aim of the study was to study the prevalence and characteristics of sinistral portal hypertension (SPH) in acute pancreatitis (AP) and its correlation with the severity of AP.

Methods: Retrospectively studied 633 patients with AP admitted to our institution and underwent magnetic resonance imaging (MRI). Diagnosis of SPH was based on clinical manifestations, laboratory tests, and MRI. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001242DOI Listing
February 2019
4 Reads

Fatty pancreas disease: clinical impact.

Vnitr Lek Fall 2018;64(10):949-952

Pancreatic steatosis is the name for a state characterized by an increased accumulation of fat in the pancreas. It is most frequently due to obesity and the metabolic syndrome, other etiological factors may include some congenital syndromes, toxic substances or viral diseases. Diagnostics is based on non-invasive imaging methods. Read More

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December 2018
18 Reads

[Diagnosis and treatment of peripancreatic infection in severe acute pancreatitis].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1361-1365

PLA Center for General Surgery, Key Laboratory of Pancreatic Injury and Repair of Sichuan Province, General Hospital of Chengdu Military Command, Chengdu 610083, China.Email:

The peripancreatic infection is a severe complication during severe acute pancreatitis. Early diagnosis, effective prevention and timely treatment are directly associated to prognosis. In recent years, with the promotion and application of the concept of damage control and the rapid development of imaging intervention techniques, the treatment for peripancreatic infection has become "multi-step, step-up" minimally invasive surgical strategy from early laparotomy. Read More

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December 2018
16 Reads

A Rare Cause of Acute Hepatopancreatitis in a Nepalese Teen.

Case Rep Pediatr 2018 21;2018:8456503. Epub 2018 Nov 21.

Department of Pediatrics, Grande International Hospital, Dhapasi, Kathmandu, Nepal.

Background: Acute pancreatitis (AP) coexisting with acute hepatitis (AH) in children is uncommon. Moreover, a single bacterial cause explaining both the complications is even rarer. Despite familiarity with the usual presentation of enteric fever, atypical presentations can go unnoticed. Read More

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http://dx.doi.org/10.1155/2018/8456503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280230PMC
November 2018
4 Reads