11,483 results match your criteria Acute Pancreatitis Imaging


IgG4/IgG RNA ratio does not accurately discriminate IgG4-related disease from pancreatobiliary cancer.

JHEP Rep 2020 Aug 14;2(4):100116. Epub 2020 Apr 14.

Department of Gastroenterology & Hepatology, The Amsterdam Gastroenterology & Metabolism (AG&M) Research Institute, The Netherlands.

Background & Aims: IgG4-related disease (IgG4-RD) of the biliary tract and pancreas is often difficult to distinguish from pancreatobiliary cancer. The blood IgG4/IgG RNA ratio has been reported to discriminate IgG4-RD from primary sclerosing cholangitis/pancreatobiliary cancer with high accuracy. This study aimed to prospectively assess the diagnostic accuracy of the blood IgG4/IgG RNA ratio for distinguishing IgG4-RD from cancer in patients with a suspected pancreatobiliary malignancy. Read More

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http://dx.doi.org/10.1016/j.jhepr.2020.100116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332528PMC

Retrospective cohort study demonstrates that modified CT Severity Index directly correlates with lipase values at or above 600.

Authors:
John F Hamer

Ann Med Surg (Lond) 2020 Aug 20;56:169-172. Epub 2020 Jun 20.

Department of Radiology, La Grange, Il, 60525, USA.

Background: Elevated lipase is considered an important biomarker for pancreatitis. The aim of this study was to assess a potential correlation between elevated lipase and characteristic imaging findings, as per the well-established Modified CT Severity index (MCTSI).

Materials And Methods: This retrospective, single centre cohort study reviewed the radiologic findings and medical records of 200 consecutive patients with elevated lipase values. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332493PMC

Strictures, stones and cysts: an unusual cause of pancreatitis in a 20-month-old female child.

BMJ Case Rep 2020 Jul 8;13(7). Epub 2020 Jul 8.

Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, Virginia, USA.

Choledochal cysts are dilations of the biliary tree that cause a variety of clinical symptoms and can lead to several types of complications. Choledochal cysts are most commonly diagnosed in childhood and frequently present with abdominal pain, jaundice and, in infants, an abdominal mass. Although the most concerning complication is malignant transformation of the cyst epithelium, other complications such as stone formation, acute pancreatitis and stricture can also occur and lead to patient morbidity. Read More

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http://dx.doi.org/10.1136/bcr-2020-234966DOI Listing

Diagnostic performance of EUS in non-jaundiced patients with an incidental finding of double duct sign on cross-sectional imaging: A systematic review and meta-analysis.

Pancreatology 2020 Jun 8. Epub 2020 Jun 8.

Kings College Hospital, London, UK.

Background/objectives: Dilatation of the pancreatic duct and common bile duct, known as double duct sign (DDS), suggests sinister pathology at the periampullary region. Non-jaundiced patients with incidental DDS and otherwise normal cross-sectional imaging present a diagnostic dilemma to the multidisciplinary team (MDT). The primary aim of this review was to assess the diagnostic yield of endoscopic ultrasound (EUS) in detecting causal pathology in this patient population. Read More

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http://dx.doi.org/10.1016/j.pan.2020.05.008DOI Listing

Reduced Skeletal Muscle Volume and Increased Skeletal Muscle Fat Deposition Characterize Diabetes in Individuals after Pancreatitis: A Magnetic Resonance Imaging Study.

Diseases 2020 07 1;8(3). Epub 2020 Jul 1.

School of Medicine, University of Auckland, Auckland 1023, New Zealand.

Background: Skeletal muscle has been implicated in the pathogenesis of type 2 diabetes but it has never been investigated in diabetes after pancreatitis. The aim was to investigate the relationship between psoas muscle volume (PMV) and diabetes in individuals after pancreatitis, as well as its associations with ectopic fat phenotypes and insulin traits.

Methods: Individuals after an attack of pancreatitis and healthy individuals were studied in a cross-sectional fashion. Read More

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http://dx.doi.org/10.3390/diseases8030025DOI Listing

Finding a needle in a haystack: Endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic masses in the setting of chronic pancreatitis.

Ann Gastroenterol 2020 Jul-Aug;33(4):418-425. Epub 2020 May 10.

Division of Gastroenterology and Hepatology (Bhaveshkumar Patel, Muslim Atiq).

Background: The mainstay for the definitive diagnosis of pancreatic lesions is endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). However, there is evidence that EUS-FNA has low sensitivity in the setting of chronic pancreatitis (CP). This single-center retrospective study aimed to compare and analyze the diagnostic yield of EUS-FNA for solid pancreatic lesions in the presence and absence of CP, and to further investigate strategies for overcoming the low diagnostic yield in the setting of CP. Read More

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http://dx.doi.org/10.20524/aog.2020.0484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315714PMC

Advanced MR Imaging of the Pancreas.

Magn Reson Imaging Clin N Am 2020 Aug 3;28(3):353-367. Epub 2020 Jun 3.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 North University Boulevard, Suite UH0663, Indianapolis, IN 46202, USA. Electronic address:

MR imaging can be optimized to evaluate a spectrum of pancreatic disorders with advanced sequences aimed to provide quantitative results and increase MR diagnostic capabilities. The pancreas remains a challenging organ to image because of its small size and location deep within the body. Besides its anatomic limitations, pancreatic pathology can be difficult to identify in the early stages. Read More

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http://dx.doi.org/10.1016/j.mric.2020.03.003DOI Listing

Detection of Lipase Activity in Cells by a Fluorescent Probe Based on Formation of Self-Assembled Micelles.

iScience 2020 Jun 20;23(7):101294. Epub 2020 Jun 20.

Department of Pharmacology, Qingdao University School of Pharmacy, 308 Ningxia Road, Qingdao 266071, China; Institue of Innovative Drug Discovery, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. Electronic address:

Reliable and sensitive detection of lipase activity is essential for the early diagnosis and monitoring of acute pancreatitis or progression of digestive diseases. However, the available fluorescent probes for detection of lipase activity are only implemented in a hexane-water two-phase system due to the nature of heterogeneous catalysis of lipase, thus limiting their applications in direct imaging of lipase activity in living cells and tissues. Here we designed and synthesized a "turn on" fluorescent probe CPP based on self-assembled micelles for hydrolysis of lipase. Read More

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http://dx.doi.org/10.1016/j.isci.2020.101294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334599PMC

Autoimmune pancreatitis type 2.

Curr Opin Gastroenterol 2020 Jun 28. Epub 2020 Jun 28.

Department of Medicine, Pancreas Institute, University of Verona, Verona, Italy.

Purpose Of Review: Type 2 autoimmune pancreatitis (AIP) is a rare inflammatory disease of the pancreas. Very few data have been published on this particular subtype, which differs from the 'classical' IgG4-related type 1 AIP in terms of pathological features, epidemiology and risk of relapse. The aim of the current review is to summarize the available literature, suggesting a diagnostic and therapeutic approach to this disease. Read More

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http://dx.doi.org/10.1097/MOG.0000000000000655DOI Listing

Exploring the neglected segment of the intestine: the duodenum and its pathologies.

Pol J Radiol 2020 8;85:e230-e244. Epub 2020 May 8.

Department of Radiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Herein we reviewed the computed tomography (CT) findings of a spectrum of pathological entities affecting the duodenum. We discuss the CT findings of some congenital, inflammatory, traumatic, and neoplastic pathologies of the duodenum along with the conventional barium studies of selected conditions. Pathologies of this C-shaped intestinal segment, derived from both foregut and midgut, are often overlooked in clinical practice and radiological literature. Read More

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http://dx.doi.org/10.5114/pjr.2020.95477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315055PMC

Management of Gallstone-Induced Acute Pancreatitis in Pregnancy: A Tertiary-Center Experience.

Sisli Etfal Hastan Tip Bul 2018 21;52(2):92-96. Epub 2018 May 21.

Department of General Surgery, Kanuni Sutan Suleyman Training and Research Hospital, Istanbul, Turkey.

Objectives: Gallbladder stones are the most frequently reported etiology of acute pancreatitis in pregnancy and are often diagnosed in the third trimester. This condition is associated with both mother and infant morbidity and mortality, and its treatment remains controversial.

Methods: Relevant patient data between September 2010 and April 2017 from the Kanuni Sultan Suleyman Training and Research Hospital were analyzed regarding etiology (of gallstone pancreatitis), trimester of pregnancy, diagnostic tools, pancreatitis stage, clinical status, medical treatment, surgical interventions, and pregnancy status. Read More

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http://dx.doi.org/10.14744/SEMB.2017.60490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315056PMC

Nonneoplastic Lesions of the Pancreas: A Retrospective Analysis of 20 Cases.

Sisli Etfal Hastan Tip Bul 2018 30;52(1):31-35. Epub 2018 Mar 30.

Department of Pathology, Istanbul Sisli Hamidiye Etfal Application and Research Center, University of Health Sciences, Istanbul, Turkey.

Objectives: In the pancreatic lesion cases, surgery is often planned based only on imaging results and without a preoperative histological diagnosis, due to the high risk of malignancy in combination with the difficulty of invasive interventions and limited cytopathological evaluation. In this study, the records of 20 patients who had undergone a pancreatectomy procedure and who were diagnosed with nonneoplastic pancreatic lesions were retrospectively evaluated according to the clinical and histopathological findings.

Methods: A total of 122 cases of patients who underwent a pancreatectomy with suspicious lesions between 2004 and 2016 were retrospectively assessed in detail using the clinical and histopathological findings. Read More

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http://dx.doi.org/10.14744/SEMB.2017.88598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315078PMC

Mycoplasma hominis bursitis in a simultaneous pancreas-kidney transplant recipient; case report and literature review.

Transpl Infect Dis 2020 Jun 30:e13392. Epub 2020 Jun 30.

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.

Mycoplasma hominis can be isolated frequently from the genitourinary tract of some healthy individuals. On rare occasions, it acts as a pathogen in immunocompromised patients such as transplant recipients. Here we describe the case of a 39 year-old-man with end stage kidney disease secondary to diabetic nephropathy who received a simultaneous kidney-pancreas transplant. Read More

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http://dx.doi.org/10.1111/tid.13392DOI Listing

Challenging biliary strictures: pathophysiological features, differential diagnosis, diagnostic algorithms, and new clinically relevant biomarkers - part 1.

Therap Adv Gastroenterol 2020 16;13:1756284820927292. Epub 2020 Jun 16.

Department of Medicine, Geneva University, Geneva, Switzerland.

It is frequently challenging to make the correct diagnosis in patients with biliary strictures. This is particularly important as errors may have disastrous consequences. Benign-appearing strictures treated with stents may later be revealed to be malignant and unnecessary surgery for benign strictures carries a high morbidity rate. Read More

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http://dx.doi.org/10.1177/1756284820927292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298429PMC

Various Modalities Accurate in Diagnosing a Disrupted or Disconnected Pancreatic Duct in Acute Pancreatitis: A Systematic Review.

Dig Dis Sci 2020 Jun 27. Epub 2020 Jun 27.

Department of Surgery, St. Antonius Hospital, PO 2500, 3430 EM, Nieuwegein, The Netherlands.

Background: Severe pancreatitis may result in a disrupted pancreatic duct, which is associated with a complicated clinical course. Diagnosis of a disrupted pancreatic duct is not standardized in clinical practice or international guidelines. We performed a systematic review of the literature on imaging modalities for diagnosing a disrupted pancreatic duct in patients with acute pancreatitis. Read More

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http://dx.doi.org/10.1007/s10620-020-06413-0DOI Listing

Rare coincidence of intraductal papillary mucinous neoplasm and type 1 autoimmune pancreatitis.

Clin J Gastroenterol 2020 Jun 27. Epub 2020 Jun 27.

Department of Gastroenterology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295, Japan.

The present case involved a 60-year-old man with autoimmune pancreatitis (AIP). While his AIP was in remission for 6 years, a follow-up CE-CT revealed a dilated main pancreatic duct (MPD) and an enhanced mural nodule. Fluorodeoxyglucose uptake was positive on positron emission tomography. Read More

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http://dx.doi.org/10.1007/s12328-020-01162-zDOI Listing

Left-sided portal hypertension caused by idiopathic splenic vein stenosis improved by splenectomy: a case report.

Surg Case Rep 2020 Jun 26;6(1):148. Epub 2020 Jun 26.

Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.

Background: Splenic vein stenosis and occlusion, which are known causes of left-sided portal hypertension, often occur secondary to trauma, pancreatitis, or invasion or compression by pancreatic tumors. However, few reports have described idiopathic splenic vein stenosis.

Case Presentation: A 70-year-old man was referred to our hospital for examination of isolated gastric varices. Read More

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http://dx.doi.org/10.1186/s40792-020-00912-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316945PMC

Usefulness of endoscopic ultrasound-guided fine-needle biopsy for the diagnosis of autoimmune pancreatitis using a 22-gauge Franseen needle: a prospective multicenter study.

Endoscopy 2020 Jun 24. Epub 2020 Jun 24.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background:  Detailed histological evaluation is important in the diagnosis of autoimmune pancreatitis (AIP). However, it remains challenging to obtain adequate tissue from the pancreas. Recently, several reports have suggested the usefulness of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using the new "core" needles for acquiring pancreatic tissue. Read More

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http://dx.doi.org/10.1055/a-1183-3583DOI Listing

A Summertime Stupor.

Cureus 2020 May 22;12(5):e8242. Epub 2020 May 22.

Internal Medicine, University of Arizona, Tucson, USA.

Most commonly seen with alcohol use disorder in the developed world, Wernicke's encephalopathy (WE), a disorder caused by thiamine deficiency can be readily missed in the setting of other predisposing conditions such as malnutrition, the most common cause worldwide. We present a case of a 21-year-old female with sudden progressive decline in her level of alertness and mentation along with severe hypothermia who had clinical features and imaging findings consistent with WE in the setting of pancreatitis and chronic gastritis. WE should be suspected in all patients who present with altered mental status (AMS) and who are at an increased risk of malnutrition despite a normal or high body mass index, so that treatment with thiamine may be initiated and further neurologic sequelae can be averted. Read More

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http://dx.doi.org/10.7759/cureus.8242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306676PMC

Association between autoimmune pancreatitis and ulcerative colitis: a report of 12 patients.

Rev Esp Enferm Dig 2020 Jun 24;112. Epub 2020 Jun 24.

Gastroenterología, Hospital Clínico Universidad de Chile, Chile.

Introduction: pancreatic manifestations in inflammatory bowel disease (IBD) mainly include acute pancreatitis secondary to drugs and, less frequently, autoimmune pancreatitis, in particular type 2 autoimmune pancreatitis.

Methods: retrospective study of patients diagnosed with ulcerative colitis (UC) and autoimmune pancreatitis (AIP) in control at two centers in Santiago, Chile, between 2007 and 2018. Clinical data, laboratory results, images and response to treatment were recorded. Read More

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http://dx.doi.org/10.17235/reed.2020.6677/2019DOI Listing

Three cases of follicular pancreatitis: association between radiological findings and pathological features.

J Surg Case Rep 2020 Jun 15;2020(6):rjaa134. Epub 2020 Jun 15.

Department of Integrated Diagnostic Pathology, Nippon Medical School, Tokyo, Japan.

Follicular pancreatitis (FP) is characterized by nodular mass composed of lymphoid hyperplasia and fibrosis. We here present radiological and pathological features of three cases of FP. The three patients were middle- or old-aged men, and nodular mass was pointed out at health examination. Read More

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http://dx.doi.org/10.1093/jscr/rjaa134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297552PMC

Percutaneous catheter drainage of walled-off necrosis in acute pancreatitis: "Not so inferior" to endoscopic or surgical drainage.

Authors:
Pankaj Gupta

Pancreatology 2020 Jun 16. Epub 2020 Jun 16.

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2020.04.023DOI Listing

Pulmonary complications in dogs with acute presentation of pancreatitis.

BMC Vet Res 2020 Jun 22;16(1):209. Epub 2020 Jun 22.

Department of Veterinary Sciences, Veterinary Teaching Hospital "Mario Modenato", University of Pisa, Via Livornese Lato monte, San Piero a Grado, 56122, Pisa, Italy.

Background: In humans, respiratory complications in patients with acute pancreatitis (AP) are a common life-threatening comorbidity. Since possible lung impairment has not been individually evaluated in canine AP, the aims of the present study were to: (1) describe the prevalence, types and severity of pulmonary complications in dogs with acute presentation of AP, and (2) evaluate their association with mortality. AP diagnosis was based on compatible clinical and laboratory parameters, abnormal canine pancreatic-lipase test, and positive abdominal ultrasound within 48 h from admission. Read More

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http://dx.doi.org/10.1186/s12917-020-02427-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310026PMC

Toward the Clinical Development and Validation of a Thy1-Targeted Ultrasound Contrast Agent for the Early Detection of Pancreatic Ductal Adenocarcinoma.

Invest Radiol 2020 Jun 18. Epub 2020 Jun 18.

From the Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, Palo Alto, CA.

Early detection of pancreatic ductal adenocarcinoma (PDAC) represents the most significant step toward the treatment of this aggressive lethal disease. Previously, we engineered a preclinical Thy1-targeted microbubble (MBThy1) contrast agent that specifically recognizes Thy1 antigen overexpressed in the vasculature of murine PDAC tissues by ultrasound (US) imaging. In this study, we adopted a single-chain variable fragment (scFv) site-specific bioconjugation approach to construct clinically translatable MBThy1-scFv and test for its efficacy in vivo in murine PDAC imaging, and functionally evaluated the binding specificity of scFv ligand to human Thy1 in patient PDAC tissues ex vivo. Read More

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http://dx.doi.org/10.1097/RLI.0000000000000697DOI Listing

Abdominal Manifestations of Sickle Cell Disease.

Curr Probl Diagn Radiol 2020 Jun 1. Epub 2020 Jun 1.

Department of Radiology and Imaging, Medical College of Georgia, Augusta, GA.

Sickle cell disease is a debilitating hematologic process that affects the entire body. Disease manifestations in the abdomen most commonly result from vaso-occlusion, hemolysis, or infection due to functional asplenia. Organ specific manifestations include those involving the liver (eg, hepatopathy, iron deposition), gallbladder (eg, stone formation), spleen (eg, infarction, abscess formation, sequestration), kidneys (eg, papillary necrosis, infarction), pancreas (eg, pancreatitis), gastrointestinal tract (eg, infarction), reproductive organs (eg, priapism, testicular atrophy), bone (eg, marrow changes, avascular necrosis), vasculature (eg, vasculopathy), and lung bases (eg, acute chest syndrome, infarction). Read More

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http://dx.doi.org/10.1067/j.cpradiol.2020.05.012DOI Listing

Mannose: Good player and assister in pharmacotherapy.

Biomed Pharmacother 2020 Jun 18;129:110420. Epub 2020 Jun 18.

Marine Medical Research Institute of Guangdong Zhanjiang (GDZJMMRI), Southern Marine Science and Engineering Guangdong Laboratory Zhanjiang, Guangdong Medical University, Zhanjiang, China; Guangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmaceutical Science, Guangdong Medical University, Zhanjiang, China. Electronic address:

Mannose is a monosaccharide widely distributed in body fluids and tissues, especially in the nerve, skin, testicles, retina, liver and intestines. It is used to synthesize glycoproteins and participate in immune regulation. In recent years, mannose has been applied more and more widely in the biomedical context as people have a deeper understanding of its biological effects. Read More

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http://dx.doi.org/10.1016/j.biopha.2020.110420DOI Listing

Split-bolus single-pass CT for vascular complications in acute pancreatitis: assessment of radiation dose and multi-phasic contrast enhancement compared to single-bolus multi-pass CT.

Clin Radiol 2020 Jun 16. Epub 2020 Jun 16.

Department of Radiology, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge, CB2 0QQ, UK.

Aim: To assess vascular contrast enhancement and radiation dose of split-bolus single-pass computed tomography (CT) compared to single-bolus multi-pass CT for acquiring a multi-phasic study.

Materials And Methods: Patients who underwent CT for acute pancreatitis were included retrospectively. Thirty consecutive patients scanned with a split-bolus protocol were compared to 30 consecutive patients scanned with a single-bolus protocol. Read More

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http://dx.doi.org/10.1016/j.crad.2020.05.002DOI Listing

Validation of threshold values for pancreas thickness and T1-weighted signal intensity ratio in the pediatric pancreas.

Pediatr Radiol 2020 Jun 16. Epub 2020 Jun 16.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Background: Pancreas atrophy and the loss of T1-weighted signal intensity by magnetic resonance imaging (MRI) are findings of chronic pancreatitis.

Objective: The purpose of this study was to test published normal values and cutoffs for pancreas thickness and the pancreas:spleen T1-weighted signal intensity ratio in children without pancreatic disease.

Materials And Methods: This was a secondary analysis of prospectively collected MRI data for 50 children (range: 6. Read More

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http://dx.doi.org/10.1007/s00247-020-04733-xDOI Listing

Acute Pancreatitis Imaging in MDCT: State of the Art of Usual and Unusual Local Complications. 2012 Atlanta Classification Revisited.

Curr Probl Diagn Radiol 2020 May 11. Epub 2020 May 11.

Departamento Imagenología, Clínica Dávila, Facultad de Medicina Universidad de los Andes y Universidad Mayor, Santiago, Chile.

Acute pancreatitis is an inflammatory disease in which most common etiologies are biliary lithiasis and alcoholism. Acute pancreatitis can be classified into 2 groups according to its morphologic features: interstitial edematous pancreatitis and necrotizing acute pancreatitis. The prognosis of this group of diseases and its complications varies significantly and contrast-enhanced computed tomography is the imaging study of choice for the diagnosis and detection of complications. Read More

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http://dx.doi.org/10.1067/j.cpradiol.2020.04.002DOI Listing

European Guideline on IgG4-related digestive disease - UEG and SGF evidence-based recommendations.

United European Gastroenterol J 2020 Jul 18;8(6):637-666. Epub 2020 Jun 18.

See list at the end of this article.

The overall objective of these guidelines is to provide evidence-based recommendations for the diagnosis and management of immunoglobulin G4 (IgG4)-related digestive disease in adults and children. IgG4-related digestive disease can be diagnosed only with a comprehensive work-up that includes histology, organ morphology at imaging, serology, search for other organ involvement, and response to glucocorticoid treatment. Indications for treatment are symptomatic patients with obstructive jaundice, abdominal pain, posterior pancreatic pain, and involvement of extra-pancreatic digestive organs, including IgG4-related cholangitis. Read More

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http://dx.doi.org/10.1177/2050640620934911DOI Listing

Single-stage treatment with ERCP and laparoscopic cholecystectomy versus two-stage treatment with ERCP followed by laparoscopic cholecystectomy within six to eight weeks: a retrospective study.

Turk J Surg 2019 Sep 31;35(3):178-184. Epub 2019 May 31.

Clinic of General Surgery, Necip Fazil City Hospital, Kahramanmaras, Turkey.

Objectives: Obstructive jaundice is one of the earliest symptoms of a hepatobiliary system disorder. The aim of the present study was to compare single stage endoscopic retrograde cholangiopancreatography (ERCP)/laparoscopic cholecystectomy (LC) and two-stage ERCP and LC with respect to the frequency of imaging, duration of anesthesia and the length of stay in our clinic.

Material And Methods: Of the 350 patients undergoing ERCP between 01. Read More

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http://dx.doi.org/10.5152/turkjsurg.2018.4204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795219PMC
September 2019

Complex Pancreaticobiliary Maljunction with Pancreas Divisum and Obstructive Pseudocyst.

J Clin Imaging Sci 2020 25;10:31. Epub 2020 May 25.

Departments of Radiology, Tripler Army Medical Center, 1 Jarrett White Rd., Honolulu, Hawaii, United States.

Pancreaticobiliary maljunction (PBM) is the congenital junction of the bile and pancreatic ducts into a common channel located anatomically outside of the duodenal wall. The complex type (Type D) is the rarest type and occurs in conjunction with other pancreaticobiliary anomalies. We present a case of complex PBM with pancreas divisum presenting as acute pancreatitis and obstructive symptoms secondary to a pancreatic pseudocyst. Read More

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http://dx.doi.org/10.25259/JCIS_17_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294320PMC

Reply to Letter to Editor-"Catheter-Related Complications of Percutaneous Drainage in Step-up Approach for Management of Pancreatic Necrosis".

J Gastrointest Surg 2020 Jun 15. Epub 2020 Jun 15.

Division of Surgical Gastroenterology, Department of General Surgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1007/s11605-020-04685-5DOI Listing

Biloma: A Rare Manifestation of Spontaneous Bile Leak.

Cureus 2020 May 14;12(5):e8116. Epub 2020 May 14.

Geriatrics, MedStar Franklin Square Medical Center, Baltimore, USA.

A biloma is an intrahepatic or extrahepatic encapsulated collection of bile outside of the biliary tree and within the abdominal cavity. Hepatobiliary interventions and laparoscopic cholecystectomy are the most common etiologies of biloma followed by abdominal trauma, choledocholithiasis, and biliary dilation secondary to biliary stricture. We report a case of a 91-year-old female who presented to the emergency room with an acute onset of epigastric and right upper quadrant sharp pain for one day that radiated to the back, and was associated with two to three episodes of vomiting. Read More

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http://dx.doi.org/10.7759/cureus.8116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292700PMC

Locally Invasive Pancreatic Adenocarcinoma Presenting in the Splenic Flexure: A Rare Case Report.

Cureus 2020 May 13;12(5):e8085. Epub 2020 May 13.

General Surgery, Grandview Medical Center, Dayton, USA.

Pancreatic adenocarcinoma is a malignant cancer seen predominantly in males presenting with high-risk factors including chronic pancreatitis, familial history of cancer, and tobacco and alcohol abuse. The etiology of pancreatic adenocarcinoma is deceptive, and research continues to investigate its molecular patterns. Herein, we present a case of a 74-year-old Caucasian male who presented to the emergency department (ED) with tarry stools and hematochezia in the rectum for two weeks. Read More

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http://dx.doi.org/10.7759/cureus.8085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292687PMC

Cost effectiveness of intraoperative laparoscopic ultrasound for suspected choledocholithiasis; outcomes from a specialist benign upper gastrointestinal unit.

Ann R Coll Surg Engl 2020 Jun 15:1-6. Epub 2020 Jun 15.

Torbay Hospital, Torquay, Devon, UK.

Introduction: Common bile duct stones are present in 10% of patients with symptomatic gallstones. One-third of UK patients undergoing cholecystectomy will have preoperative ductal imaging, commonly with magnetic resonance cholangiopancreatography. Intraoperative laparoscopic ultrasound is a valid alternative but is not widely used. Read More

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http://dx.doi.org/10.1308/rcsann.2020.0109DOI Listing

Nondiagnostic fine needle aspirates of the pancreas: A root cause analysis.

Cancer Cytopathol 2020 Jun 11. Epub 2020 Jun 11.

Department of Pathology, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Background: Fine needle aspiration (FNA) of the pancreas is considered the primary and least invasive diagnostic method in the evaluation of pancreatic lesions. A nondiagnostic sample may trigger repeat FNA or a more invasive diagnostic procedure. The goal of this study was to identify the root causes of nondiagnostic samples. Read More

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http://dx.doi.org/10.1002/cncy.22301DOI Listing

Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: abdominal, hepatobiliary, and gastrointestinal conditions.

3D Print Med 2020 Jun 8;6(1):13. Epub 2020 Jun 8.

Department of Radiology and The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

Background: Medical 3D printing has demonstrated value in anatomic models for abdominal, hepatobiliary, and gastrointestinal conditions. A writing group composed of the Radiological Society of North America (RSNA) Special Interest Group on 3D Printing (SIG) provides appropriateness criteria for abdominal, hepatobiliary, and gastrointestinal 3D printing indications.

Methods: A literature search was conducted to identify all relevant articles using 3D printing technology associated with a number of abdominal pathologic processes. Read More

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http://dx.doi.org/10.1186/s41205-020-00065-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278118PMC

Computed Tomography-guided 125I Radioactive Seed Implantation Therapy for Pancreatic Cancer Pain.

J Coll Physicians Surg Pak 2020 Apr;30(4):364-368

Department of Radiotherapy, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.

Objective: This study aimed to evaluate the short-term curative effect of computed tomography (CT) guided radioactive 125I (125-Iodine) seed implantation (CTRISI) therapy for advanced pancreatic cancer patients pain.

Study Design: Interventional study.

Place And Duration Of Study: Imaging Department and Oncology Department, First Affiliated Hospital of Zhengzhou University, China, from January 2015 to March 2017. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.04.364DOI Listing

Chronic pancreatitis: an overview of diagnosis and management.

Expert Rev Gastroenterol Hepatol 2020 Jun 8:1-11. Epub 2020 Jun 8.

Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS , Rome, Italy.

Introduction: Chronic pancreatitis entails a heavy burden on the healthcare system because of its often protracted evolution, requiring complex diagnostic and therapeutic procedures.

Areas Covered: This review focuses on novel imaging and endoscopic diagnostic and therapeutic interventions that have changed the management of patients with chronic pancreatitis. We have conducted an extensive search of original papers and guidelines, in order to provide a comprehensive and up to date review of available evidence in these areas of interest. Read More

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http://dx.doi.org/10.1080/17474124.2020.1774365DOI Listing

A Single-Center Experience With Percutaneous Interventional Management of Refractory Chylous Ascites.

Can Assoc Radiol J 2020 Jun 8:846537120929429. Epub 2020 Jun 8.

Division of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada.

Purpose: Management of chylous ascites is poorly understood with no management guidelines. We retrospectively reviewed patients treated for chylous ascites at our institution to evaluate efficacy and safety of lipiodol lymphangiography and embolization.

Materials And Methods: Seven patients underwent percutaneous interventional management of chylous ascites (average age 52. Read More

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http://dx.doi.org/10.1177/0846537120929429DOI Listing

Endoscopic management of pancreaticopleural fistula in a pediatric patient: A case report and literature review.

Medicine (Baltimore) 2020 Jun;99(23):e20657

Department of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Introduction: Pancreaticopleural fistula (PPF) is a rare but serious complication of pancreatic disorders. As the clinical presentations of PPF are often deceptive, it can cause a delay in the timely diagnosis and proper treatment. PPF is extremely uncommon in pediatric patients, and diagnostic and management strategies for PPF among pediatric patients are scanty. Read More

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http://dx.doi.org/10.1097/MD.0000000000020657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306390PMC
June 2020
5.723 Impact Factor

Trajectories of glycaemia following acute pancreatitis: a prospective longitudinal cohort study with 24 months follow-up.

J Gastroenterol 2020 Jun 3. Epub 2020 Jun 3.

School of Medicine, University of Auckland, Room 12.085 A, Level 12, Auckland City Hospital, Auckland, 1142, New Zealand.

Background: New-onset diabetes is the most common sequela of acute pancreatitis (AP). Yet, prospective changes in glycaemia over time have never been investigated comprehensively in this study population. The primary aim was to determine the cumulative incidence of new-onset prediabetes and new-onset diabetes after AP over 24 months of follow-up in a prospective cohort study. Read More

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http://dx.doi.org/10.1007/s00535-020-01682-yDOI Listing

PANCREATIC STEATOSIS: A NEW DIAGNOSIS AND THERAPEUTIC CHALLENGE IN GASTROENTEROLOGY.

Arq Gastroenterol 2020 Apr-Jun;57(2):216-220

University Hospital of North Cumbria, Department of Gastroenterology, UK.

Fat infiltration in the pancreas is called pancreatic steatosis and it has several synonyms such as pancreatic lipomatosis, non-alcoholic fatty pancreatic disease, lipomatous pseudohypertrophy, fatty replacement, fatty pancreas and fatty infiltration. Pancreatic steatosis describes a disease ranging from infiltration of fat in the pancreas to pancreatic inflammation, and development of pancreatic fibrosis. There are multiple aetiologies of this condition, such as metabolic syndrome, alcohol intake, viral infections, toxins, congenital syndromes, etc. Read More

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http://dx.doi.org/10.1590/s0004-2803.202000000-27DOI Listing
October 2019

Effectiveness of Photodynamic Screening Using 5-Aminolevulinic Acid for the Diagnosis of Pancreatic Cancer.

Anticancer Res 2020 Jun;40(6):3571-3577

The Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan.

Background/aim: We evaluated urinary levels of porphyrin metabolites, such as uroporphyrin (UP) and coproporphyrin (CP), after 5-Aminolevulinic acid (ALA) administration in patients with or without pancreatic cancer (PaC).

Patients And Methods: Sixty-seven subjects with PaC, 11 with pancreatitis, and 9 with normal pancreas (NP) were enrolled. Urine samples from all subjects were collected prior to ALA administration and at more than 4 hours after ALA administration. Read More

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http://dx.doi.org/10.21873/anticanres.14347DOI Listing

A case report for a diagnostic dilemma of a giant intra-abdominal cyst with an uncertain origin.

Authors:
Nern Hoong Kao

Int J Surg Case Rep 2020 6;71:374-377. Epub 2020 Feb 6.

Department of General Surgery, Changi General Hospital, Singapore. Electronic address:

Introduction: Giant intra-abdominal cystic lesions are seldom encountered and can post a diagnostic challenge pre-operatively. These often present as increasing abdominal size and from its mass effect.

Presentation Of Case: Here, we present a case of a 58 year-old gentleman with worsening bloating and abdominal distension. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322736PMC
February 2020

Modified Puestow Procedure for Chronic Pancreatitis in a Child Due to Annular Pancreas and Duodenal Duplication: A Case Report.

Pediatr Gastroenterol Hepatol Nutr 2020 May 8;23(3):304-309. Epub 2020 May 8.

Department of Pediatric Surgery, Reproductive and Developmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

An 18-year-old woman with annular pancreas and duodenal duplication presented with recurrent acute pancreatitis and underwent a resection of duodenal duplication. However, the patient experienced recurrent abdominal pain after resection. Abdominal computed tomography and magnetic resonance imaging showed a dilatation of the peripheral pancreatic duct and stenosis and malformation of both the Wirsung's and Santorini's duct due to multiple stones. Read More

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http://dx.doi.org/10.5223/pghn.2020.23.3.304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231747PMC

Endoscopic papillectomy of benign papillary tumors: A single-center experience.

Medicine (Baltimore) 2020 May;99(22):e20414

Department of Gastroenterology, Changhai Hospital, Changhai Road 168, Shanghai.

Endoscopic treatment of duodenal papillary tumors is well described. This study aims to provide new evidence for the treatment of benign papillary tumors through comparisons between endoscopic snare papillectomy (ESP) and endoscopic mucosal resection (EMR).Between May 2010 and December 2017, 72 patients were enrolled. Read More

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http://dx.doi.org/10.1097/MD.0000000000020414DOI Listing
May 2020
5.723 Impact Factor