11,268 results match your criteria Acute Inflammatory Demyelinating Polyradiculoneuropathy

Guillain-Barré Syndrome Likely due to Relapsing Hepatitis A.

Case Reports Hepatol 2021 26;2021:5570027. Epub 2021 May 26.

Department of Internal Medicine, Methodist Dallas Medical Center, Dallas, TX 75203, USA.

Guillain-Barré syndrome (GBS) is an immune-mediated disease of the peripheral nervous system that can be caused by various bacterial and virologic agents. The disease is characterized by progressive muscle weakness and paralysis. Rarely, GBS is preceded by an acute infection with hepatitis A. Read More

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Cardiogenic Shock and Guillain-Barré Syndrome as the First Manifestations of Pheochromocytoma.

Case Rep Endocrinol 2021 3;2021:6691095. Epub 2021 Jun 3.

Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Febrile congestive heart failure is a rare first manifestation of pheochromocytoma. Herein, the case of a 31-year-old female with febrile congestive heart failure and subsequent cardiogenic shock is presented. After intensive care unit (ICU) admission and further evaluating the right adrenal mass observed in abdominal ultrasonography, the diagnosis of pheochromocytoma was confirmed. Read More

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Guillain Barré syndrome associated with COVID-19- lessons learned about its pathogenesis during the first year of the pandemic, a systematic review.

Autoimmun Rev 2021 Jun 10:102875. Epub 2021 Jun 10.

Unidad de Enfermedades Sistémicas e Inmunopatología, Servicio de Medicina Interna, Hospital Clínico Universitario de Santiago de Compostela, Spain.

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Steroid myopathy in a child with diffuse alveolar hemorrhage: a case report.

Ann Palliat Med 2021 Jun 6. Epub 2021 Jun 6.

Department of Respiratory Medicine, Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai, China.

Steroid myopathy (SM) is a side effect of glucocorticoid administration. Previous reports of SM after glucocorticoid therapy for respiratory diseases have focused on asthma and chronic obstructive pulmonary disease in adults or adolescents. To our knowledge, there have been no reports of SM after treatment with glucocorticoid for diffuse alveolar hemorrhage (DAH) in preschoolers. Read More

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?Mini-review:_Guillain Barrè syndrome and myelitis associated with SARS-CoV-2 infection_?

Neurosci Lett 2021 Jun 9:136040. Epub 2021 Jun 9.

Emergency Neurology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.

Despite a likely underestimation due to the many obstacles of the highly infectious, intensive care setting, increasing clinical reports about COVID-19 patients developing acute paralysis for polyradiculoneuritis or myelitis determine additional impact on the disease course and outcome. Different pathogenic mechanisms have been postulated basing on clinical, laboratory and neuroimaging features, and response to treatments. Here we provide an overview with insights built on the available reports. Read More

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NF-κB inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type.

Clin Exp Immunol 2021 Jun 12. Epub 2021 Jun 12.

Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.

Guillain-Barre' syndrome (GBS) is an acute inflammatory and immune-mediated demyelinating disease of peripheral nervous system (PNS). Macrophages play a central role in its animal model, experimental autoimmune neuritis (EAN), which has been well-accepted. Additionally, NF-κB inhibitors has been used to treat cancers and showed beneficial effects. Read More

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Emerging Infection, Vaccination, and Guillain-Barré Syndrome: A Review.

Neurol Ther 2021 Jun 12. Epub 2021 Jun 12.

Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.

Guillain-Barré syndrome (GBS) is an autoimmune disorder of the peripheral nervous system that typically develops within 4 weeks after infection. In addition to conventional infectious diseases with which we are familiar, emerging infectious diseases, such as Zika virus infection and coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have also been suggested to be associated with GBS. GBS is mainly categorized into a demyelinating subtype known as acute inflammatory demyelinating polyneuropathy (AIDP) and an axonal subtype known as acute motor axonal neuropathy (AMAN). Read More

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SARS-CoV-2 associated or post partum Guillain Barre syndrome?

Josef Finsterer

J Clin Neurosci 2021 Jun 2. Epub 2021 Jun 2.

Klinik Landstrasse, Messerli Institute, Vienna, Austria. Electronic address:

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[Guillain-Barré syndrome as a probable first symptom of severe acute respiratory syndrome Coronavirus 2 in an elderly patient].

Rev Esp Geriatr Gerontol 2021 Apr 27. Epub 2021 Apr 27.

Unidad Territorial de Geriatría y Curas Paliativas de Osona, Hospital Universitari de Vic i Hospital de la Santa Creu de Vic, Barcelona, España.

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Dimensions of SARS-CoV-2 associated Guillain-Barré syndrome.

J Finsterer R Ghosh

J Neuroimmunol 2021 Jun 5;357:577626. Epub 2021 Jun 5.

Department of General Medicine, Burdwan Medical College & Hospital, Burdwan, West Bengal, India.

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Freiburg Neuropathology Case Conference : A 42-year-old Patient with Progressive Neurological Deficits, Multiple Brain Lesions and Accompanying Affection of Peripheral Nerves.

Clin Neuroradiol 2021 Jun 11. Epub 2021 Jun 11.

Departments of Neuroradiology, Medical Centre, University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacherstr. 64, 79106, Freiburg, Germany.

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Guillain-Barré syndrome variant occurring after SARS-CoV-2 vaccination.

Ann Neurol 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurology, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Whilst SARS-CoV-2 vaccines are very safe, we report four cases of the bifacial weakness with paraesthesias variant of Guillain-Barré syndrome (GBS) occurring within three weeks of vaccination with the Oxford-AstraZeneca SARS-CoV-2 vaccine. This rare neurological syndrome has previously been reported in association with SARS-CoV-2 infection itself. Our cases were given either intravenous immunoglobulin, oral steroids, or no treatment. Read More

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Guillain-Barré syndrome following ChAdOx1-S/nCoV-19 vaccine.

Ann Neurol 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurology, Division of Neurocritical Care, University of Kansas Medical Center, Kansas City, KA, USA.

As of April 22, 2021, around 1.5 million individuals in 3 districts of Kerala, India had been vaccinated with COVID-19 vaccines. Over 80% of these individuals (1. Read More

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Guillain-Barré Syndrome With a Peculiar Course: A Case Report.

Cureus 2021 May 8;13(5):e14905. Epub 2021 May 8.

Pediatrics, Emergency Clinical Hospital for Children, Cluj-Napoca, ROU.

Guillain-Barré syndrome (GBS) or acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is a rare autoimmune disorder in which the body's immune system mistakenly attacks the nerves. In this report, we present a case of a 15-month-old girl who presented with an inability to walk and support the vertical and sitting positions, pain in the lower limbs accompanied by grimaces, muscular weakness, and agitation due to gait disturbances. This is a unique case in that GBS affected a previously healthy girl and was associated with pneumonia and anemia as the disease progressed, causing an intriguing diagnosis. Read More

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Estimation of the latent therapeutic demand for immunoglobulin therapies in autoimmune neuropathies in the United States.

Vox Sang 2021 Jun 10. Epub 2021 Jun 10.

Private Consultant in Neurology, Milan, Italy.

Background And Objectives: The use of immunoglobulin (IG) solutions as an immunomodulatory therapy in certain neurological conditions has become an established modality and represents a significant proportion of total IG use. The estimation of the evidence-based potential demand designated as the latent therapeutic demand (LTD) for IG in these diseases is required for adequate planning of the plasma supply required to manufacture the product.

Materials And Methods: The diseases studied included chronic inflammatory demyelinating polyneuropathy (CIDP), Guillain-Barré syndrome (GBS) and multifocal motor neuropathy (MMN). Read More

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Iatrogenic immune-mediated neuropathies: diagnostic, epidemiological and mechanistic uncertainties for causality and implications for clinical practice.

J Neurol Neurosurg Psychiatry 2021 Jun 8. Epub 2021 Jun 8.

Inflammatory Neuropathy Clinic, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

Acute and chronic immune-mediated neuropathies have been widely reported with medical intervention. Although causal relationship may be uncertain in many cases, a variety of drugs, several vaccination types, surgical procedures and bone marrow transplants have been reported as possible cause or trigger of a putative immune-mediated response resulting in acute and chronic neuropathies. We conducted a systematic review of the literature from 1966 to 2020 on reported cases of possible iatrogenic immune-mediated neuropathies. Read More

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Intravenous immunoglobulin treatment for mild Guillain-Barré syndrome: an international observational study.

J Neurol Neurosurg Psychiatry 2021 Jun 8. Epub 2021 Jun 8.

Department of Neurology, Erasmus MC, Rotterdam, The Netherlands

Objective: To compare the disease course in patients with mild Guillain-Barré syndrome (GBS) who were treated with intravenous immunoglobulin (IVIg) or supportive care only.

Methods: We selected patients from the prospective observational International GBS Outcome Study (IGOS) who were able to walk independently at study entry (mild GBS), treated with one IVIg course or supportive care. The primary endpoint was the GBS disability score four weeks after study entry, assessed by multivariable ordinal regression analysis. Read More

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To treat or not to treat mild Guillain-Barré syndrome: limited evidence for but still none against.

J Neurol Neurosurg Psychiatry 2021 Jun 8. Epub 2021 Jun 8.

Regional Neuromuscular clinic, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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Guillain-Barré Syndrome after Novel Coronavirus Disease 2019.

J Emerg Med 2021 Mar 26. Epub 2021 Mar 26.

Department of Neurology, Staten Island University Hospital, Staten Island, New York; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, New York.

Background: Novel coronavirus disease 2019 (COVID-19) has affected more than 89 million people worldwide. As the pandemic rages on, more complications of the disease are being recognized, including stroke, cardiovascular disease, thromboembolic events, encephalopathy, seizures, and more. Peripheral nervous system involvement, particularly Guillain-Barré syndrome (GBS), is of special interest, given the increasing reports of cases related to COVID-19. Read More

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Electrophysiological characteristics of patients with nitrous oxide abuse.

Neurol Res 2021 Jun 8:1-9. Epub 2021 Jun 8.

Department of Neurology, The First Hospital of China Medical University, Shenyang, China.

: In the young generations with nitrous oxide abuse (NO), featured electrophysiological response of the peripheral neuropathy caused by nitrous oxide remains to be defined.: Patients with nitrous oxide abuse (20 cases), two variants of Guillain-Barré syndrome (GBS), that is, acute inflammatory demyelinating polyradiculoneuropathy (GBS-AIDP, 19 cases) and acute motor axonal neuropathy (GBS-AMAN, 18 cases), as well as diabetic peripheral neuropathy (DPN, 20 cases) were enrolled into this study. Electrophysiological parameters including distal motor latency (DML), motor nerve conduction velocity (MNCV), sensory nerve conduction velocity (SNCV), amplitudes of compound muscle action potential (CMAP), and sensory nerve action potential (SNAP) were measured and analyzed by comparing the parameters between the aforementioned patients groups as well as normal control group (20 subjects). Read More

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Rare and Atypical Presentations of Acute Disseminated Encephalomyelitis in Children: A Case Series.

J Trop Pediatr 2021 05;67(2)

Department of Pediatrics, Midnapore Medical College, West Bengal 721101, India.

Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelinating disorder of central nervous system occurring in children with a wide range of clinical manifestations after infection or vaccination. There are few case reports in literature, describing atypical presentations of ADEM with fever of unknown origin, autonomic dysfunction, complex movement disorders such as myoclonus, dystonia and chorea, acute psychosis and myocarditis. Here, we report four cases of ADEM with atypical features like uniocular blindness, myelin oligodendrocyte glycoprotein antibodies negative multiphasic disseminated encephalomyelitis, ADEM mimicking Guillain-Barre syndrome at presentation and isolated spinal ADEM. Read More

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Clinical and Electrophysiological Factors Predicting Prolonged Recovery in Children with Guillain-Barré Syndrome.

Indian J Pediatr 2021 Jun 7. Epub 2021 Jun 7.

Pediatric Neurology Unit, Department of Pediatrics, Bharati Vidyapeeth Deemed University Medical College, Pune, Maharashtra, 411043, India.

Objective: To compare clinical and nerve conduction studies (NCS) parameters predictive of outcome in children with acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN).

Methods: In this prospective observational study, NCS was done on all children at admission and repeated before discharge. Functional status of patients was graded as per Hughes Disability score. Read More

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Neurological manifestations and neuroimaging findings in patients with SARS-CoV2-a systematic review.

Egypt J Neurol Psychiatr Neurosurg 2021 2;57(1):68. Epub 2021 Jun 2.

Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Background: The COVID-19 pandemic has drastically affected everyone in a hit or miss manner. Since it began, evidence of the neuro-invasive potential of the virus has been intensifying significantly. Several pathways have been hypothesized to elucidate the neurotropic nature of SARS-CoV2. Read More

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Genotypical Relationship Between Human and Poultry Strains of Campylobacter jejuni.

Curr Microbiol 2021 Jun 5. Epub 2021 Jun 5.

Laboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.

This study aimed to compare the genotype diversity of C. jejuni isolates. From the total of 64 C. Read More

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A case report of Guillain-Barré syndrome in a pregnant woman infected by COVID-19.

Acta Neurol Belg 2021 Jun 3. Epub 2021 Jun 3.

Student's Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

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Bilateral Facial Palsy: A Clinical Approach.

Cureus 2021 Apr 25;13(4):e14671. Epub 2021 Apr 25.

Family Medicine, Schulich School of Medicine & Dentistry, Western University, London, CAN.

Bilateral facial palsy (BFP) is exceedingly rare, representing only 0.3%-2.0% of facial palsy cases. Read More

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Risk factors for the severity of Guillain-Barré syndrome and predictors of short-term prognosis of severe Guillain-Barré syndrome.

Sci Rep 2021 Jun 2;11(1):11578. Epub 2021 Jun 2.

Department of Neurology, The affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000, Shandong, People's Republic of China.

Guillain-Barré syndrome (GBS) is a neurological disorder characterized by paralysis. Identifying the severity, appropriate therapeutic method, and prognosis of GBS at an early stage is highly important. This study aimed to investigate the modifiable risk factors for the severity of GBS and consequent need for mechanical ventilation (MV) and to identify clinical predictive factors for poor short-term outcomes of severe GBS. Read More

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Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature.

Ital J Pediatr 2021 Jun 2;47(1):123. Epub 2021 Jun 2.

Department of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.

Objectives: To describe clinical characteristics, laboratory tests, radiological data and outcome of pediatric cases with SARS-CoV-2 infection complicated by neurological involvement.

Study Design: A computerized search was conducted using PubMed. An article was considered eligible if it reported data on pediatric patient(s) with neurological involvement related to SARS-CoV-2 infection. Read More

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