2,472 results match your criteria Acute Febrile Neutrophilic Dermatosis


Necrotizing Cellulitis and Myositis in a Neutropenic Leukemic Patient.

Cureus 2021 May 10;13(5):e14941. Epub 2021 May 10.

Internal Medicine, Moffitt Cancer Center, Tampa, USA.

In this article, we review a case of necrotizing cellulitis and myositis in a neutropenic leukemic patient. He underwent a series of investigations to reach the diagnosis of pyoderma gangrenosum (PG). The lesion improved dramatically after pertinent identification and initiation of appropriate treatment. Read More

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A Sweet Voice: Acute Febrile Neutrophilic Dermatosis of the Larynx.

Ear Nose Throat J 2021 Jun 12:1455613211022098. Epub 2021 Jun 12.

Department of Otorhinolaryngology, 23387The Mayo Clinic Arizona, Phoenix, AZ, USA.

Significance Statement: Acute febrile neutrophilic dermatosis (Sweet syndrome) is a rare idiopathic condition characterized by fever and whole-body rash of tender erythematous plaques of unknown etiology. Otorhinolaryngologic manifestations of the disease can be severe, yet they are sparsely reported in the literature. We present the first documented case of laryngeal involvement of Sweet syndrome. Read More

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Sweet Syndrome Associated with Ixazomib.

Turk J Haematol 2021 Jun 11. Epub 2021 Jun 11.

Aydın Adnan Menderes University Medical Faculty, Division of Hematology, Aydın, Turkey.

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Data-Driven Clustering Approach to Derive Taste Perception Profiles from Sweet, Salt, Sour, Bitter, and Umami Perception Scores: An Illustration among Older Adults with Metabolic Syndrome.

J Nutr 2021 Jun 10. Epub 2021 Jun 10.

Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.

Background: Current approaches to studying relations between taste perception and diet quality typically consider each taste-sweet, salt, sour, bitter, umami-separately or aggregately, as total taste scores. Consistent with studying dietary patterns rather than single foods or total energy, an additional approach may be to study all 5 tastes collectively as "taste perception profiles."

Objective: We developed a data-driven clustering approach to derive taste perception profiles from taste perception scores and examined whether profiles outperformed total taste scores for capturing individual variability in taste perception. Read More

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Pulmonary Involvement in Sweet's Syndrome.

Am J Respir Crit Care Med 2021 Jun 8. Epub 2021 Jun 8.

Westchester Medical Center, 8138, Pulmonary and Critical Care Medicine, Valhalla, New York, United States.

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Skin biopsies in acute myeloid leukemia patients undergoing intensive chemotherapy are safe and effect patient management.

Sci Rep 2021 Jun 7;11(1):11940. Epub 2021 Jun 7.

Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center - Beilinson Hospital, 39 Zeev Jabotinsky St., 4941492, Petach Tikva, Israel.

There is paucity of data regarding the diagnostic yield and safety of skin biopsies in patients with acute myeloid leukemia (AML), though skin eruptions are common in these patients. We evaluated 216 patients treated in our hemato-oncology unit at a tertiary medical center between 2007 and 2018 and identified 35 patients who underwent 37 skin biopsies. The majority of biopsies were performed during induction treatment for AML (n = 26, 70%), whereas the remainder of biopsies were done prior to induction initiation (n = 8, 22%) or during consolidation chemotherapy (n = 3, 8%). Read More

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BIOACTIVITY, BIOAVAILABILITY, AND GUT MICROBIOTA TRANSFORMATIONS OF DIETARY PHENOLIC COMPOUNDS: IMPLICATIONS FOR COVID-19.

J Nutr Biochem 2021 Jun 2:108787. Epub 2021 Jun 2.

Núcleo Integrado de Desenvolvimento em Análises Laboratoriais (NIDAL), Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.

The outbreak of mysterious pneumonia at the end of 2019 is associated with widespread research interest worldwide. The coronavirus disease-19 (COVID-19) targets multiple organs through inflammatory, immune, and redox mechanisms, and no effective drug for its prophylaxis or treatment has been identified until now. The use of dietary bioactive compounds, such as phenolic compounds (PC), has emerged as a putative nutritional or therapeutic adjunct approach for COVID-19. Read More

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Starchy Vegetables and Metabolic Syndrome in Costa Rica.

Nutrients 2021 May 13;13(5). Epub 2021 May 13.

Department of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.

Only a few studies primarily examined the associations between starchy vegetables (other than potatoes) and metabolic syndrome (MetS). We aimed to evaluate the association between starchy vegetables consumption and MetS in a population-based sample of Costa Rican adults. We hypothesized that a higher overall intake of starchy vegetables would not be associated with higher MetS prevalence. Read More

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Myocarditis Concurrent with Sweet Syndrome: A Presentation of Acute Myeloid Leukemia.

Case Rep Hematol 2021 11;2021:6621007. Epub 2021 May 11.

University of Kentucky Markey Cancer Center, 800 Rose Street, Lexington, KY 40536, USA.

Acute myeloid leukemia (AML) is the most common acute leukemia in American adults and portends a poor prognosis if untreated. Commonly, AML presents with symptoms related to concurrent leukopenia, anemia, or thrombocytopenia; however, due to its ability to affect many organ systems in the body, AML can have a highly varied clinical presentation. One such presentation is myocarditis, which is a rarely reported manifestation of AML. Read More

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Sweet Syndrome and Secondary Syphilis in a Person with Acute Necrotizing Tonsillitis.

Case Rep Dermatol 2021 Jan-Apr;13(1):216-221. Epub 2021 Apr 15.

Ben-Gurion University of the Negev, Beersheba, Israel.

Syphilis has received its classical designation as one of "the great imitators," reflecting a wide variety of symptoms and presentations, which can cause difficulties in diagnosis. Here we report an unusual case of secondary syphilis in a person with acute necrotizing tonsillitis and Sweet syndrome. A 33-year-old female presented with fever, bilateral cervical lymphadenopathy, tonsillar enlargements with ulcerated pus-filled lesions on the right tonsil, and multiple pseudovesicular, mammillated, edematous plaques on her neck, face, and extremities. Read More

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Sweet syndrome as a cutaneous manifestation in a patient with bacteremia: A case report.

IDCases 2021 8;24:e01148. Epub 2021 May 8.

Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand.

is a gram-positive bacillus causing three clinical syndromes in humans, including localized cutaneous infection, diffuse cutaneous form, and systemic infection. Various skin lesions in systemic form have been reported; however, no comprehensive study has been conducted. Here we report a case of a 60-year-old woman who suffered from bacteremia with distinct generalized annular purplish plaques. Read More

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Enasidenib-induced Sweet syndrome with differentiation syndrome.

Authors:
Amr Mohamed

Clin Case Rep 2021 May 19;9(5):e04099. Epub 2021 May 19.

Department of Internal Medicine Rochester General Hospital Rochester NY USA.

Multiple conditions such as drug rash, thromboembolism, sepsis, and heart failure can mimic differentiation syndrome; therefore, maintaining a high index of suspicion is important, as the prognosis is usually good if adequately treated. Read More

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Azathioprine hypersensitivity syndrome: report of two cases.

BMJ Case Rep 2021 May 19;14(5). Epub 2021 May 19.

Pharmacy, Cairns Base Hospital, Cairns, Queensland, Australia.

Azathioprine hypersensitivity syndrome is a rare but potentially severe side effect of azathioprine use. It has a variable and non-specific presentation making it difficult to distinguish from sepsis or disease relapse. High clinical suspicion is therefore required for recognition and prompt cessation of azathioprine for symptom resolution. Read More

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Sorghum as Biofuel Crop: Interdisciplinary Methods to Enhance Productivity (Botany, Genetics, Breeding, Seed Technology, and Bioengineering).

Methods Mol Biol 2021 ;2290:253-270

Department of Soils and Environment, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai, India.

Sorghum is a versatile crop cultivated since time immemorial. It fulfills the basic needs of mankind in the contest of food, feed, fodder, nutrition, and pharmaceutical uses. Now it adds one more paramount importance as a second-generation biofuel. Read More

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January 2021

Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization.

Reprod Biol Endocrinol 2021 May 15;19(1):72. Epub 2021 May 15.

Department of IVF unit, Private Adatip Hospital, Yenisehir mahallesi Kardelen sokak 2, Pendik, 34912, Istanbul, Turkey.

Background: MicroRNAs (miRNAs) are small RNA molecules that modulate post-transcriptional gene regulation. They are often used as promising non-invasive biomarkers for the early diagnosis of cancer. However, their roles in assisted reproduction are still unknown. Read More

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[China prime diet quality score].

Wei Sheng Yan Jiu 2021 Mar;50(2):198-204

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

Objective: To Develop the China Prime Diet Quality Score(CPDQS) and evaluate the relationship between dietary quality and health-related outcomes in Chinese adults.

Methods: CPDQS was conducted by 22 components, including dark green vegetables, dark red/orange vegetables, other vegetables, dark yellow fruits, citrus fruits, other fruits, whole grains/legumes, sweet potato, other potatoes, soybean, nuts, poultry, fish and shrimp, milk, eggs, red meat, fried food, refined grains, sugar sweetered beverages, salt, cooking oil, and alcohol. CPDQS components were selected based on Chinese Dietary Guidelines, and the values of each CPDQS components were set according to the dietary recommendations of foods and nutrients. Read More

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[Research progress and discussion on traditional Chinese medicine properties of Kaempferia parviflora].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1951-1959

School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.

Kaempferiae Parviflorae Rhizoma is the dried rhizome of Kaempferia parviflora in Zingiberaceae. It is originated and widely distributed in Thailand and other tropical and subtropical regions, where it has been used as food and medicine for thousands of years. K. Read More

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Sweet Syndrome with Perifollicular Involvement due to Koebnerization from Facial Hair Plucking.

J Cutan Pathol 2021 May 12. Epub 2021 May 12.

Department of Dermatology, UMass Memorial Health Care, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

Sweet Syndrome (SS), also known as acute febrile neutrophilic dermatosis, is an uncommon skin eruption characterized by fever, leukocytosis, and tender erythematous papules, nodules, and plaques. Histopathologically, SS lesions are characterized by marked superficial papillary edema with a dense neutrophilic infiltrate. SS is known to demonstrate both the Koebner phenomenon and pathergy. Read More

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Characterizing the presence of neutrophil extracellular traps in neutrophilic dermatoses.

Exp Dermatol 2021 May 9. Epub 2021 May 9.

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of multiple inflammatory dermatoses. However, characterization of NETs in neutrophilic dermatoses was performed on very limited number of patients; this limitation precluded definitive conclusions. In this case series of 57 patients, we compared the amounts of neutrophils producing NETs in cutaneous lesions of different entities of neutrophilic dermatoses (17 with pyoderma gangrenosum, 37 with Sweet's syndrome and three with subcorneal pustular dermatosis). Read More

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Emerging Skin Toxicities in Patients with Breast Cancer Treated with New Cyclin-Dependent Kinase 4/6 Inhibitors: A Systematic Review.

Drug Saf 2021 May 6. Epub 2021 May 6.

Department of Dermatology, San Gallicano Dermatological Institute-IRCCS, Via Elio Chianesi 53, 00144, Rome, Italy.

Three cyclin-dependent kinases 4/6, including palbociclib, ribociclib, and abemaciclib, have been approved for the treatment of patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative advanced breast cancer. The objective of this study was to evaluate the occurrence and clinical spectrum of cutaneous adverse events in patients with breast cancer following therapy with cyclin-dependent kinase 4/6 inhibitors. A systematic literature search was performed in the PubMed, Cochrane, and EMBASE databases up to November 2020 to evaluate studies published from 2015 to 2020. Read More

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[Prevalence of health problems in midlife Swiss warm-blooded horses].

Schweiz Arch Tierheilkd 2021 May;163(5):339-350

Institut suisse de médecine équine (ISME), Vetsuisse-Fakultät, Universität Bern und Agroscope, Avenches.

Introduction: The breeding of a healthy horse is the basic requirement for optimal performance. This is also specifically stated in the breeding goal of the Swiss warmblood horse and should be achieved through a strict selection of the stallions. The aim of this retrospective study was to assess the current state of the population to optimize breeding. Read More

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Successful use of baricitinib in the treatment of refractory rheumatoid arthritis-associated Sweet syndrome.

Clin Exp Dermatol 2021 Apr 29. Epub 2021 Apr 29.

Integral Rheumatology & Immunology Specialists, Plantation, FL, USA.

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The complex relationship between metabolic syndrome and sweeteners.

J Food Sci 2021 May 28;86(5):1511-1531. Epub 2021 Apr 28.

Tecnologico de Monterrey, Escuela de Ingenieria y Ciencias, Zapopan, Jal, Mexico.

Metabolic syndrome is a multifactorial disorder originating from central obesity through a high caloric intake and a sedentary lifestyle. Metabolic syndrome increases the risk of type 2 diabetes (T2D) disease, converting it to one of the costliest chronic diseases, which reduces life quality. A strategy proposed by the food industry to reduce this problem is the generation of low-caloric products using sweeteners, which are compounds that can substitute sucrose, given their sweet taste. Read More

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Systematic review: Sweet syndrome associated with inflammatory bowel disease.

J Crohns Colitis 2021 Apr 23. Epub 2021 Apr 23.

Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, Ohio.

Background And Aims: Sweet syndrome (SS) is a dermatologic condition associated with both IBD and azathioprine use. We performed a systematic review to better delineate clinical characteristics and outcomes of SS in IBD patients.

Methods: Peer-reviewed, full-text journal publications from inception to April 2020 in English language and adult subjects with IBD were included. Read More

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Acute Cardiac Injury in Coronavirus Disease 2019 and Other Viral Infections-A Systematic Review and Meta-Analysis.

Crit Care Med 2021 Apr 19. Epub 2021 Apr 19.

Department of Medicine, McGill University, Montreal, PQ, Canada. Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Division of Pulmonary and Critical Care Medicine, Department of Medicine, New York Presbyterian Hospital, Columbia University, New York, NY. Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada. Centre for Health Evaluation and Outcomes Science (CHEOS), University of British Columbia, Vancouver, BC, Canada. Department of Medicine, Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Department of Critical Care Medicine, Queen's University, Kingston, ON, Canada. Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. Divisions of Internal Medicine and Infectious Diseases, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.

Objectives: Severe acute respiratory syndrome-related coronavirus-2 binds and inhibits angiotensin-converting enzyme-2. The frequency of acute cardiac injury in patients with coronavirus disease 2019 is unknown. The objective was to compare the rates of cardiac injury by angiotensin-converting enzyme-2-binding viruses from viruses that do not bind to angiotensin-converting enzyme-2. Read More

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Sweet syndrome with bitter outcomes in cervical cancer: A case report.

Gynecol Oncol Rep 2021 May 16;36:100749. Epub 2021 Mar 16.

University of Texas Medical Branch, Department of Obstetrics & Gynecology, United States.

Background: Sweet Syndrome, or acute febrile neutrophilic dermatosis, is a non-infectious, painful rash accompanied by fever, leukocytosis and skin biopsy showing neutrophilic dermal inflammation. It is either idiopathic, drug-induced or malignancy associated (MASS). MASS is uncommon in cervical cancer, and usually signals diagnosis, progression or recurrence. Read More

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The effects of foot massage on hemodialysis patients' sleep quality and restless leg syndrome: a comparison of lavender and sweet orange essential oil topical application.

J Complement Integr Med 2021 Apr 12. Epub 2021 Apr 12.

Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Objectives: Hemodialysis (HD) patients suffer more sleep problems (poor sleep quality and restless leg syndrome [RLS]). Complementary therapy, especially massage with aromatherapy oil is one of the non-pharmacological treatment options with less adverse effects than routine methods. The purpose of this study was to determine the effects of foot massage with of lavender and orange essential oil on HD patients' sleep quality and RLS. Read More

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Transformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing sweet syndrome.

Dermatol Reports 2021 Mar 17;13(1):9017. Epub 2021 Mar 17.

Research Division, Hospital de Especialidades Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

The Sweet's syndrome, is an inflammatory skin disorder characterized by extensive infiltration of neutrophils in the dermis with extension to the subcutis, known as acute febrile neutrophilic dermatosis. It may occur as a paraneoplastic syndrome. To our knowledge, there are currently few reports about transformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing Sweet syndrome in the literature. Read More

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mTOR inhibitors reduce enteropathy, intestinal bleeding and colectomy rate in juvenile polyposis of infancy due to PTEN-BMPR1A deletion syndrome.

Hum Mol Genet 2021 Apr 2. Epub 2021 Apr 2.

Translational Gastroenterology Unit, University of Oxford, Oxford, United Kingdom.

Background: Ultrarare genetic disorders can provide proof of concept for efficacy of targeted therapeutics and reveal pathogenic mechanisms relevant to more common conditions. Juvenile polyposis of infancy (JPI) is caused by microdeletions in chromosome 10 that result in haploinsufficiency of two tumor suppressor genes: phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and bone morphogenetic protein receptor, type IA (BMPR1A). Loss of PTEN and BMPR1A results in a much more severe phenotype then deletion of either gene alone, with infantile onset pan-enteric polyposis and a high mortality rate. Read More

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Simultaneously complete but not partial taste and smell losses were associated with SARS-CoV-2 infection.

Int J Infect Dis 2021 May 2;106:329-337. Epub 2021 Apr 2.

Bamrasnaradura Infectious Diseases Institute, Department of Disease Control, Nonthaburi, Thailand.

Objectives: The aim of this study was to investigate the association between taste and smell losses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and to elucidate whether taste preference influences such taste loss.

Methods: A matched case-control study was conducted in 366 Thai participants, including 122 who were confirmed SARS-CoV-2-positive by RT-PCR (case group) and 244 who were SARS-CoV-2-negative (control group). Taste, smell, and appetite changes were assessed by self-reported visual analog scale. Read More

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