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    1 OF 148

    Fine Needle Aspiration Cytology of Papulonodular Lesions of Skin: A Study of 50 Cases.
    J Clin Diagn Res 2016 Dec 1;10(12):EC09-EC13. Epub 2016 Dec 1.
    Professor and Head of Department, Department of Pathology, JSS Medical College, JSS University , Mysuru, Karnataka, India .
    Introduction: Skin is one of the frequent site of disease in human body. Fine Needle Aspiration Cytology (FNAC) is a safe diagnostic method in these cases. FNAC has some limitation, particularly related to representativity of samples, exact typing of skin adnexal tumours and classifying the nature of metastatic cutaneous nodules. Read More

    Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature.
    Intern Med 2017 15;56(4):449-453. Epub 2017 Feb 15.
    Department of Respiratory Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.
    Pulmonary actinomycosis is a rare pulmonary infection that often exhibits unspecific symptoms and radiological findings. We herein report a case of pulmonary actinomycosis that mimicked pulmonary aspergilloma in an immunocompetent patient. Read More

    Unusual Behavior of a Posttraumatic Scar: Craniofacial Actinomycosis.
    Wounds 2017 Jan;29(1):E1-E4
    Division of Plastic Surgery, Sir Gangaram Hospital, New Delhi, India.
    Actinomycosis is a chronic suppurative granulomatous infection most commonly involving the cervicofacial region. Clinical diagnosis is usually difficult, and fine-needle aspiration cytology or imaging studies are usually unhelpful in diagnosing actinomycosis. Definitive diagnosis is based on the histopathological examination of a tissue biopsy. Read More

    Facial Actinomycosis Mimicking a Cutaneous Tumor.
    Wounds 2017 Jan;29(1):10-13
    Pamukkale University Hospital, Department of Plastic, Reconstructive and Aesthetic Surgery, Denizli, Turkey.
    Actinomycosis is a chronic granulomatous infection that commonly occurs in the cervicofacial region. Although Actinomcyes is an element of the normal oral flora, infections of the facial skin are very rare because of the entirely endogenous habitation of the organism. The authors report a case of facial actinomycosis, which mimicked a cutaneous tumor both clinically and surgically in a 44-year-old woman with chronic renal failure and Hepatitis C viral infection. Read More

    Cervicofacial Primary Cutaneous Actinomycosis: Surgical Treatment for Complete Remission of the Disease.
    J Craniofac Surg 2017 Jan 30. Epub 2017 Jan 30.
    Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Actinomycosis, an infectious bacterial disease caused by Actinomyces species, is very rare and is characterized by contiguous spreading, subacute to chronic granulomatous inflammation and the formation of multiple abscesses and sinus tracts that may discharge sulfur granules. Actinomycosis that presents on the skin without endogenous origin is called primary cutaneous actinomycosis, and the occurrence and treatment of primary cutaneous actinomycosis is rarely reported. This report describes the treatment of primary cervicofacial actinomycosis with a literature review, and emphasizes the importance of surgical option for complete remission of the disease. Read More

    Assessing Fifty Years of General Health Surveillance of Roe Deer in Switzerland: A Retrospective Analysis of Necropsy Reports.
    PLoS One 2017 19;12(1):e0170338. Epub 2017 Jan 19.
    Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
    General wildlife health surveillance is a valuable source of information on the causes of mortality, disease susceptibility and pathology of the investigated hosts and it is considered to be an essential component of early warning systems. However, the representativeness of data from such surveillance programs is known to be limited by numerous biases. The roe deer (Capreolus capreolus capreolus) is the most abundant ungulate and a major game species all over Europe. Read More

    Actinomycosis of the abdominal wall after cholecystectomy: transferral theory.
    Neth J Med 2016 Dec;74(10):451-454
    Departments of Internal Medicine and Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands.
    Abdominal actinomycosis is a rare disease caused by Gram-positive anaerobic Actinomyces bacteria. Here, we present a patient with an intrauterine contraceptive device who developed a long lasting and unexplained recurrent, painful abdominal swelling a few months after a laparoscopic cholecystectomy. Read More

    Primary Cutaneous Actinomycosis along with the Surgical Scar on the Hand.
    Case Rep Infect Dis 2016 9;2016:5943932. Epub 2016 Nov 9.
    Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Primary cutaneous actinomycosis is a rare clinical form with variable presentation. The tumoral presentation of actinomycosis as pseudocarcinomatous or sarcomatous masses is completely rare. The management of cutaneous actinomycosis needs proper antibiotic treatment and surgical resection would not be adequate alone. Read More

    Abdominal Actinomycosis in Children: A Case Report and Literature Review.
    Pediatr Infect Dis J 2017 Mar;36(3):e76-e79
    From the *Division of Pediatric Infectious Diseases, Department of Pediatrics and Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; †Division of Infectious Diseases, Department of Pediatrics, ‡Department of Pathology, §Department of Surgery, ¶Department of Radiology, and ‖Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California and Children's Hospital Los Angeles, Los Angeles, California.
    Abdominal actinomycosis is an uncommon pediatric infection that often manifests with a tumor-like lesion. We describe a previously healthy 11-year-old girl who presented with right lower quadrant abdominal pain and drainage. Computed tomography scan showed an abdominal wall mass. Read More

    [A case of mediastinum actinomycosis by Aggregatibacter actinomycetemcomitans].
    Rev Pneumol Clin 2016 Dec 24;72(6):363-366. Epub 2016 Oct 24.
    Pôle de spécialités cancérologiques, service de chirurgie thoracique et vasculaire, hôpital Avicenne, faculté de médecine SMBH, université Paris 13, Assistance publique-Hôpitaux de Paris (AP-HP), CHU Paris-Seine-Saint-Denis, 125, rue de Stalingrad, 93000 Bobigny, France.
    The actinomycosis is a suppurative infection due to an anaerobic and microaerophillic bacteria called actinomyces. Only few case reports are described for the mediastinal locations of this rare entity. We report a new case of inflammatory pseudotumor in the mediastinum due to Aggregatibacte actinomycetemcomitans revealed by hemoptysis. Read More

    Nasal NK/T-cell lymphoma: A tragic case.
    Eur Ann Otorhinolaryngol Head Neck Dis 2016 Oct 24. Epub 2016 Oct 24.
    Service d'ORL et de Chirurgie Cervico-faciale, Hôpital 20-Août-1953, Casablanca, Morocco.
    Introduction: Nasal NK/T-cell lymphoma is a rare clinicopathological entity, formerly called midline lethal granuloma. Following progress in histology and the routine use of immunohistochemistry, nasal NK/T-cell lymphoma was recognized as a distinct entity by WHO in 2001.

    Case Report: The authors report the case of a 22-year-old, insulin-dependent diabetic woman, who presented with mid-facial inflammatory swelling following facial trauma, initially diagnosed and treated as cellulitis of the face. Read More

    [Appendicular actinomycosis as a cause of ileocecal mass in children: Case report].
    Cir Pediatr 2015 Jul 20;28(3):137-141. Epub 2015 Jul 20.
    Servicio de Cirugía Pediátrica. Área Materno-Infantil. Hospital Universitario Vall d'Hebron. Barcelona.
    Introduction: Appendicular actinomycosis is a rare disease produced by cecal appendix invasion by Actinomyces gender bacteria after a predisposing cause that disrupts mucosal barrier, such as acute appendicitis. The highest frequency appears in adults; however, there are cases in paediatric age described in literature. The aim of this article is to introduce a case of appendicular actinomycosis in a child with atypical presentation and to review the literature. Read More

    Empyema Secondary to Actinomyces meyeri Treated Successfully with Ceftriaxone Followed by Doxycycline.
    Case Rep Infect Dis 2016 26;2016:9627414. Epub 2016 Sep 26.
    General and Acute Medicine, Mater Dei Hospital, Msida, Malta.
    Actinomycosis is a relatively rare infection caused by Gram-positive bacteria. We present the case of a 54-year-old, previously healthy, male patient with a history of severe penicillin allergy who developed severe pneumonia and empyema caused by Actinomyces meyeri. Presenting symptoms included productive cough, right upper quadrant pain, and chills and rigors. Read More

    Primary actinomycosis of vulva with inguinal lymphadenopathy.
    Indian Dermatol Online J 2016 Sep-Oct;7(5):402-405
    Department of Skin and VD, Government Medical College, Akola, Maharashtra, India.
    Actinomycosis is a chronic suppurative granulomatous infection of subcutaneous tissues caused by bacterium Actinomyces israelii. It is a normal commensal of the oral cavity, gastrointestinal tract, respiratory tract, and vagina. Infection is first established locally by breach of mucosal barrier during various procedures, aspiration, trauma, or human bite. Read More

    Persistence of a Cervical Neck Mass, Not Just the Lymphoma.
    Cureus 2016 Aug 23;8(8):e746. Epub 2016 Aug 23.
    Hematology/Oncology, Staten Island University Hospital.
    Actinomycosis is a rare, chronic granulomatous infection caused by gram-positive, anaerobic to microaerophilic branching filamentous bacteria. In the cervicofacial region, it usually presents as an enlarging neck mass. It remains a diagnostic challenge due to the fact that cultures show no growth in more than 50% of cases. Read More

    Isolated Actinomycotic Swelling in Right Upper Cervical Region.
    J Assoc Physicians India 2015 Dec;63(12):76-77
    Senior Consultant Pathologist, Department of Pathology, Baby Memorial Hospital, Calicut, Kerala.
    Cervicofacial actinomycosis is today a rare disease in our country. Isolated neck swelling due to actinomycosis is extremely rare. A case of 52 year old man with an isolated neck swelling due to actinomycosis without any discharging sinus is reported here. Read More

    Olecranon Osteomyelitis due to Actinomyces meyeri: Report of a Culture-Proven Case.
    Infect Chemother 2016 Sep 2;48(3):234-238. Epub 2016 Sep 2.
    Division of Infectious Diseases, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
    Actinomyces meyeri is a Gram positive, strict anaerobic bacterium, which was first described by Meyer in 1911. Primary actinomycotic osteomyelitis is rare and primarily affects the cervicofacial region, including mandible. We present an unusual case of osteomyelitis of a long bone combined with myoabscess due to A. Read More

    Actinomycosis of Finger: Case Report and Review of the Literature.
    J Clin Diagn Res 2016 Aug 1;10(8):EC19-20. Epub 2016 Aug 1.
    Medical Student, School of Medicine, Shahid Sadoughi University of Medical Sciences , Yazd, Iran .
    Cutaneous actinomycosis of finger is very unusual, chronic granulomatous disease caused by a group of anaerobic or microaerophilic Gram-positive filamentous bacteria that normally colonize the mouth, colon and urogenital tract. Actinomycosis of finger is rare but clinically important condition that requires suitable evaluation for guiding appropriate therapy. We hereby report a case of cutaneous actinomycosis of the right finger- a rare site, in a 34-year-old female patient which underwent usual treatment of surgical excision. Read More

    [Artificial illness as a result of non-medical use of anabolic androgenic steroids: A case report and a review of literature].
    Arkh Patol 2016 Jul-Aug;78(4):48-53
    Department of Pathology and Clinical Expertise, I.I. Dzhanelidze Saint Petersburg Research Institute of Emergency Care, St.-Petersburg.
    A 42-year-old female body builder who had used anabolic androgenic steroids (AASs) for 18 years to build up muscle mass died from liver rupture. The cause of the latter was multiple abscesses caused by Actinomyces, which developed in the presence of immunodeficiency. The postmortem changes in different organs were due to hormonal imbalance. Read More

    The treatment of actinomycosis mimicking a retained root tip: a confusing case.
    J Korean Assoc Oral Maxillofac Surg 2016 Aug 24;42(4):205-8. Epub 2016 Aug 24.
    Department of Dentistry, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
    Actinomycosis is an infection caused by the actinomyces genus and is associated with trauma or previous infection. A 58-year-old male patient was referred from a private dental clinic for root extraction of the lower right molar. The x-ray showed fractured root-like material distal to the distal root of the lower right second molar. Read More

    Spontaneous Bacterial Peritonitis due to Actinomyces Mimicking a Perforation of the Proximal Jejunum.
    Am J Case Rep 2016 Aug 26;17:616-20. Epub 2016 Aug 26.
    Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
    BACKGROUND Pelvic-abdominal actinomycosis is a rare chronic condition caused by an anaerobic, gram-negative rod-shaped commensal bacterium of the Actinomyces species. When Actinomyces becomes pathogenic, it frequently causes a chronic infection with granulomatous abscess formation with pus. Due to diversity in clinical and radiological presentation, actinomycosis can easily be mistaken for several other conditions. Read More

    Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy.
    BMC Infect Dis 2016 Aug 15;16(1):417. Epub 2016 Aug 15.
    Gynaeco-Obstetric and Paediatric Hospital, Yaoundé, Cameroon.
    Background: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions.

    Case Presentation: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Read More

    Rev Med Chir Soc Med Nat Iasi 2016 Apr-Jun;120(2):393-9
    We present the case of a former user of an intrauterine contraceptive device (IUD) for 10 years, diagnosed with a bulky, fixed pelvic tumor involving the internal genital organs and the recto sigmoid, causing luminal narrowing of the rectum, interpreted as locally advanced pelvic malignancy, probably of genital origin. Intraoperatively, a high index of suspicion made us collect a sample from the fibrous wall of the tumor mass, large Actinomyces colonies were thus identified. Surgery consisted in debridement, removal of a small amount of pus and appendectomy, thus avoiding a mutilating and useless surgery. Read More

    Actinomyces meyeri, a Common Agent of Actinomycosis.
    Am J Med Sci 2016 Jul 18;352(1):53-62. Epub 2016 Mar 18.
    Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
    Background: Actinomyces, particularly Actinomyces israelii, may cause indolent, persistent infections or represent normal mucosal flora, leading to management dilemmas.

    Materials And Methods: Prompted by a refractory Actinomyces meyeri infection complicating AIDS, clinical data for all Actinomyces isolates at our hospital laboratory since 1998 were analyzed.

    Results: A total of 140 cases had a positive result for Actinomyces cultures. Read More

    [Pulmonary actinomycosis and tuberculosis. A comorbidity pediatric case].
    Arch Argent Pediatr 2016 Aug 1;114(4):e233-6. Epub 2016 Aug 1.
    Servicio de Anatomía Patológica, Hospital Nacional Prof. A. Posadas, Villa Sarmiento, Buenos Aires, Argentina.
    Unlabelled: Actinomycosis is a chronic suppurative infection, produced by anaerobic Gram-positive bacteria or microaerobic Actinomyces species. It is rare in children and adolescents and it is more common in immunocompromised. Mycobacterium tuberculosis collaborates on the development of the disease. Read More

    Actinomycotic Osteomyelitis of Mandible.
    J Craniofac Surg 2016 Jul;27(5):e452-4
    Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran.
    Actinomycosis is an infection of filamentous, gram-positive anaerobic bacteria. Actinomycosis of jaw bone is rare and the diagnosis is often difficult. The aim of this patient report is to present an actinomycotic osteomyelitis of mandible in a 30-year-old male patient. Read More

    Successful treatment of mitral valve endocarditis in a dog associated with 'Actinomyces canis-like' infection.
    J Vet Cardiol 2016 Sep 27;18(3):271-7. Epub 2016 Jun 27.
    Department of Clinical Sciences and the Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, North Carolina State University, 1060 William Moore Dr., Raleigh, NC 27607, USA. Electronic address:
    Infective endocarditis, an inflammation of the endocardial surface due to invasion by an infectious agent, is more common in middle sized to large breed dogs. We herein report a case of mitral valve endocarditis in a 9-year-old male-castrated Weimaraner caused by an Actinomyces canis-like bacterium, not previously reported in association with infection in dogs. Read More

    Fungus ball in the nasal cavity mimicking a rhinolith.
    BMJ Case Rep 2016 Jun 28;2016. Epub 2016 Jun 28.
    Department of Pathology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
    A 63-year-old man presented to the outpatient department of our tertiary care hospital, with unilateral left nasal obstruction, foul smelling nasal discharge and occasional mild epistaxis. On examination, a hard greyish black mass was noted in the anteroinferior portion of the inferior turbinate, with extension posteriorly into the inferior meatus with surrounding unhealthy granulation tissue. Provisional diagnosis of rhinolith was surprisingly reversed by histopathology, which suggested the presence of an Aspergillus fungus ball with Actinomyces colonisation. Read More

    Abdominal manifestations of histiocytic disorders in adults: imaging perspective.
    Br J Radiol 2016 Sep 22;89(1065):20160221. Epub 2016 Jun 22.
    4 Ohio State University, Wexner Medical Center, Columbus, OH, USA.
    Histiocytic disorders (HDs) are a diverse group of diseases characterized by pathologic infiltration of normal tissues by cells of the mononuclear phagocyte system. The spectrum of these diseases ranges from treatable infectious diseases to rapidly progressive, life-threatening conditions. Although they are rare and difficult diagnoses, HDs can be diagnosed with the help of clinical and laboratory analyses, imaging features and tissue biopsy. Read More

    Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations.
    Medicine (Baltimore) 2016 Jun;95(24):e3923
    aInternal Medicine Unit, Teaching Hospital of La Réunion, France bDepartment of internal Medicine and Infectious Diseases, Teaching Hospital of Poitiers, France cDepartment of Internal Medicine, CHU Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France dInternal Medicine Unit, French Army Teaching Hospital of Metz, France eInternal Medicine Unit, Teaching Hospital of Bordeaux, France fInternal Medicine Unit, Henri Mondor Hospital, Aurillac, France.
    Actinomycosis is a rare heterogeneous anaerobic infection with misleading clinical presentations that delay diagnosis. A significant number of misdiagnosed cases have been reported in specific localizations, but studies including various forms of actinomycosis have rarely been published.We performed a multicenter retrospective chart review of laboratory-confirmed actinomycosis cases from January 2000 until January 2014. Read More

    [Whipple's disease: A case of postmortem diagnosis].
    Arkh Patol 2016 May-Jun;78(3):49-52
    Krasnoyarsk Territorial Bureau of Pathology, Krasnoyarsk, Russia.
    The paper describes a case of the postmortem diagnosis of Whipple's disease, a rare bacterial infection, in a patient with multiple organ dysfunction showing intestinal manifestations with massive retroperitoneal lymphadenopathy. Histochemical and electron microscopic methods were used to examine the patient, which showed the morphological changes occurring in the lymph nodes and bowel and the ultrastructural characteristics of Tropheryma whipplei while examining the sections primarily fixed in formalin and embedded in paraffin. The systemic pattern of the disease is depicted. Read More

    Primary actinomycosis of breast-A diagnosis on cytology.
    Diagn Cytopathol 2016 Aug 30;44(8):693-5. Epub 2016 May 30.
    Department of Pathology, Government Medical College, Miraj, Maharashtra, India.
    Primary actinomycosis of breast is a rare disease with only a few cases reported in the literature. We present a case of a 25-year-old lactating woman with primary actinomycosis of breast which was diagnosed on cytology. The patient presented with lump in left breast with dull aching pain. Read More

    Actinomycosis after allogeneic hematopoietic stem cell transplantation despite penicillin prophylaxis.
    Transpl Infect Dis 2016 Aug 5;18(4):595-600. Epub 2016 Jul 5.
    Departement de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
    Actinomycosis is a rare chronic and multifaceted disease caused by Actinomyces species frequently mimicking malignancy or other chronic granulomatous lung diseases. We report 4 original presentations of actinomycosis arising under supposed penicillin prophylaxis in allogeneic stem cell transplantation recipients. Read More

    Cytopathology of Hepatobiliary-Related Actinomycosis.
    Acta Cytol 2016 21;60(2):179-84. Epub 2016 May 21.
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pa., USA.
    Background: The clinical diagnosis of hepatobiliary-related actinomycosis can be challenging owing to its rarity and variable presentation. Moreover, actinomycotic pseudotumors may mimic malignancy and result in unnecessary surgical resection. Herein, we present the clinical and cytopathological features of 3 cases with hepatobiliary-related actinomycosis. Read More

    [Whipple disease: a differential diagnosis of polyarthritis to keep in mind].
    Rev Med Suisse 2016 Apr;12(513):704-7
    Whipple disease is a rare and potentially fatal bacterial infection induced by a Gram-positive bacillus, Tropheryma whipplei. It is responsible for articular, digestive, neurological, ophthalmological and cardiological symptoms that occur either concomitant or isolated. Thus, the diagnosis is difficult to make and therefore often delayed. Read More

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