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    Hemolytic anemia due to native valve subacute endocarditis withinfection.
    Clin Case Rep 2018 Feb 10;6(2):376-379. Epub 2018 Jan 10.
    Division of Hematology and OncologyDepartment of Internal MedicineMaimonides Medical CenterBrooklynNew YorkUSA.
    This case highlights the importance of considering infectious etiology in the management of hemolytic anemia. Hemolytic anemia associated with infectious endocarditis is rare. Actinomyces endocarditis is a rare occurrence and is very challenging to diagnose given the challenges to culture the organism. Read More

    Osteoma with actinomycosis in a nasal cavity: A case report.
    Medicine (Baltimore) 2017 Dec;96(51):e9376
    Plus I Mi Ko clinic, Suncheon, Chonnam, Korea.
    Rationale: Osteoma with actinomycosis is a very rare disease in the nasal cavity.

    Patient Concerns: We report a case of a 17-year-old female student who presented with nasal obstruction and rhinorrhea for 6 months.

    Diagnoses: The preoperative finding was osteoma covered with yellowish polypoid material. Read More

    Extensive Cutaneous Botryomycosis With Subsequent Development of Nocardia-Positive Wound Cultures.
    J Cutan Med Surg 2018 Jan 1:1203475418755762. Epub 2018 Jan 1.
    2 Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
    Botryomycosis is a rare, chronic granulomatous infection caused by a response to bacteria, most commonly Staphylococcus aureus. Cutaneous manifestations, such as subcutaneous nodules, nonhealing ulcers, or sinus tracks, typically occur following inoculation of bacteria after trauma. Drainage from the skin lesions may contain yellow grains resembling those seen in actinomycosis and nocardiosis. Read More

    Refractory actinomycosis of the humerus.
    SAGE Open Med Case Rep 2018 9;6:2050313X17752852. Epub 2018 Jan 9.
    Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
    Actinomycosis is a chronic, opportunistic infection caused byspecies, such as. Actinomycosis in long bones is very rare. To the best of our knowledge, isolated primary actinomycosis of the humerus is rarely reported in literature. Read More

    Estimating the proportion of clinically diagnosed infectious and non-infectious animal diseases in Ganta Afeshum woreda, Eastern Tigray zone, Ethiopia.
    BMC Res Notes 2018 Jan 15;11(1):29. Epub 2018 Jan 15.
    Department of Biomedical Sciences, College of Veterinary Medicine and Animal Sciences, The University of Gondar, P.O. Box: 196, Gondar, Ethiopia.
    Objective: This study was performed with the objective of identifying the proportion of emerging and endemic livestock diseases using cross sectional survey.

    Result: A total of 285 clinically diseased animals were presented to a veterinary clinic and diagnosed tentatively based on history, clinical sign, and simple laboratory diagnostics and from the study, actinomycosis (15.83%), mastitis (15%), tick infestation (10%), respiratory diseases (9. Read More

    Neurological and neuropsychological complications in the course of chronic Whipple's disease - case report.
    Psychiatr Pol 2017 Oct 29;51(5):953-961. Epub 2017 Oct 29.
    Katedra i Klinika Neurologii, Wydział Lekarski ŚUM w Katowicach.
    Introduction: Whipple's disease (WD) is a chronic, multisystemic infectious disease caused by Gram-positive bacillus Tropheryma whipplei (T.w.). Read More

    Neurological disease may precede lymphadenopathies in Actinomyces europaeus infection.
    J Infect Public Health 2017 Dec 22. Epub 2017 Dec 22.
    Department of Public Health and Pediatrics, Microbiology and Virology Unit, University of Turin, Italy.
    Actinomyces species are part of the commensal flora of the mucous membranes of the oropharynx, gastrointestinal tract and female genital tract. Actinomyces europaeus is a short, nonmotile, facultative anaerobic rod first described in 1997, susceptible in vitro to a wide range of b-lactam antibiotics which are regarded as first choice. In this report we described the case of A. Read More

    Thoracic Actinomycosis With Infiltration of the Spine: An Oncological Pitfall.
    J Pediatr Hematol Oncol 2017 Dec 12. Epub 2017 Dec 12.
    Pediatric Hematology and Oncology, St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna.
    Thoracic actinomycosis with involvement of the vertebral column and chest wall is rare in children and may resemble malignant tumors. A 12-year-old girl was admitted to our clinic having B-symptoms, cachexia, and painful scoliosis (Karnofsky index 20%). Imaging showed a large thoracic left-sided paravertebral tumor with infiltration of the vertebrae, destruction of the chest wall and multiple intrapulmonary nodules. Read More

    Actinomycosis is not Frequent in the Periapex But is a Persistent Lesion.
    Braz Dent J 2017 Nov-Dec;28(6):688-693
    Dentistry and Health Postgraduate Program, Dental School, UFBA - Universidade Federal da Bahia, Salvador, BA, Brazil.
    Periapical actinomycosis caused by a gram-positive anaerobic pathogen characterizes a typical extra-radicular infection. This study determined the frequency and correlated the content of bacteria colonies with the of periapical actinomycosis size. The study comprised a total of 218 periapical lesions (PL) (cysts, granulomas or abscess). Read More

    [Actinomycosis revealed by ulceration of the palate and gingiva].
    Ann Dermatol Venereol 2017 Nov 28. Epub 2017 Nov 28.
    Service de dermatologie, CHU d'Amiens, 1, place Victor-Pauchet, 80000 Amiens, France; Université de Picardie-Jules-Verne, 80000 Amiens, France.
    Background: Actinomycosis is a chronic and extensive granulomatous, bacterial infection. Revelation by oral ulceration is rare.

    Patients And Methods: A 76-year-old patient with diabetes was treated with dabrafenib for stage IV melanoma. Read More

    Transmission electron microscopy helpfulness in Whipple's disease masked by immunosuppressant therapy for arthritis.
    APMIS 2018 Jan 20;126(1):92-96. Epub 2017 Nov 20.
    Section of Pathology, Department of Emergency and Organ Transplantation, University 'Aldo Moro' of Bari, Bari, Italy.
    A 61-year-old woman received a diagnosis of undifferentiated non-erosive arthritis in 2010 and assumed methotrexate and steroids in 2014. After 1 year, she experienced watery diarrhea, vomiting, fever, weight loss, and severe hypoalbuminemia, thus being admitted into our Unit. Esophagogastroduodenoscopy showed duodenal lymphangiectasia and duodenal biopsy samples several foamy PAS-positive macrophages and villous subtotal atrophy. Read More

    A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer.
    Clin J Gastroenterol 2018 Feb 9;11(1):38-41. Epub 2017 Nov 9.
    Department of Gastroenterology, Akita University Graduate School of Medicine, Hondo 1-1-1, Akita, Akita, Japan.
    A 60-year-old man presented with odynophagia after bronchial artery infusion chemotherapy for pulmonary metastasis of hepatocellular carcinoma. Esophagogastroduodenoscopy (EGD) revealed an esophageal ulcer in the middle thoracic esophagus. An esophageal biopsy demonstrated no malignancy. Read More

    A Rare Thermophilic Bug in Complicated Diverticular Abscess.
    Case Rep Gastroenterol 2017 Sep-Dec;11(3):569-575. Epub 2017 Sep 27.
    GI and Hepatology, The Brooklyn Hospital Center, Affiliate of the Mount Sinai Hospital, Brooklyn, New York, USA.
    Actinomycosis is a form of painful abscess in the gastrointestinal tract or in deep tissue caused by actinomyces species. They are one of the commensal bacteria in the oral cavity and gastrointestinal tract of humans but can opportunistically cause infection in immunosuppressive hosts through invasion of breached mucosa or necrotic tissue while mimicking malignancy, gastrointestinal tuberculosis, and inflammatory bowel, by far, the major and most common human pathogen throughout literatures. Read More

    Granulomatous Thyroiditis: A Case Report and Literature Review.
    Ann Clin Lab Sci 2017 Sep;47(5):620-624
    Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
    Background: Granulomatous disease in the thyroid gland has been linked to viral, bacterial and autoimmune etiologies. The most common granulomatous disease of the thyroid is subacute granulomatous thyroiditis, which is presumed to have a viral or post-viral inflammatory cause. Bacterial etiologies include tuberculosis, actinomycosis, and nocardiosis, but are extremely rare. Read More

    A rare coexistence of aspergillosis with actinomycosis.
    J Oral Maxillofac Pathol 2017 May-Aug;21(2):277-281
    Department of Oral and Maxillofacial Pathology, GSL Dental College, Rajahmundry, Andhra Pradesh, India.
    Aspergillosis is a common systemic mycosis which affects immunocompromised and immunocompetent hosts.spp. is wide spread in the environment in most countries, which renders an invasive form of disease. Read More

    Retroperitoneal Actinomycosis: A Rare Sequela of an Infected Obstructing Ureteral Stone.
    J Endourol Case Rep 2017 1;3(1):93-96. Epub 2017 Jul 1.
    Department of Urology, University of Minnesota Medical School, Minneapolis, Minnesota.
    Actinomycosis is a condition in which, a normal component of the oral and gastrointenstial flora, becomes pathogenic in the setting of damaged tissue, leading to widespread tissue destruction across fascial planes. Prior literature describing this condition is rare, particularly cases involving the retroperitoneum. In this study, we report a case of retroperitoneal actinomycosis caused by an infected, obstructing ureteral stone. Read More

    Pulmonary actinomycosis masquerading as lung cancer: A case report.
    Med J Malaysia 2017 Aug;72(4):246-247
    Hospital Sultanah Nora Ismail, Department of Medicine, Batu Pahat, Johor, Malaysia.
    Pulmonary actinomycosis is a rare yet important and challenging diagnosis to make. It is commonly confused with other lung diseases, such as tuberculosis and bronchogenic carcinoma, leading to delay diagnosis or misdiagnosis. A 49-year-old man presented with a chronic cough, hemoptysis, and pleuritic chest pain. Read More

    The cytopathology of Actinomyces, Nocardia, and their mimickers.
    Diagn Cytopathol 2017 Dec 9;45(12):1105-1115. Epub 2017 Sep 9.
    Department of Pathology, Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio, 44106.
    Nocardia species and Actinomyces species are 2 of the most commonly diagnosed filamentous bacteria in routine cytopathology practice. These genera share many overlapping cytomorphologic features, including their thin, beaded, branching, Gram-positive, GMS-positive filamentous structures that fragment at their peripheries into bacillary- and coccoid-appearing forms. Features that help distinguish between these 2 microorganisms include the width of their filamentous structures, the angles at which they branch, and their ability or lack thereof to retain a modified acid-fast stain. Read More

    A rare case ofempyema: Still a challenging entity to manage.
    Respir Med Case Rep 2017 12;22:203-205. Epub 2017 Aug 12.
    Pneumology in Thorax Department, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.
    is a rare pathogen and an infrequent cause of human actinomycosis. Less than ten cases were reported in the English-literature to date concerningempyema. We herein report a case to promote the awareness and adequate management of the disease. Read More

    Actinomycosis of the foot - A South African case.
    S Afr J Surg 2017 Jun;55(2):36
    Department of Surgery, Livingstone Hospital, Walter Sisulu University (WSU).
    Mycetoma is a chronic infection, characterised by severe disability and discomfort to patients. This condition is common throughout tropical regions of the world. The Indian subcontinent and north-east Africa, especially Sudan, bear the majority of the disease burden. Read More

    Actinomyces: a deceptive infection of oral cavity.
    J Korean Assoc Oral Maxillofac Surg 2017 Aug 24;43(4):282-285. Epub 2017 Aug 24.
    Department of Prosthodontics, Crown and Bridges, RKDF Dental College, Bhopal, India.
    Actinomycosis is an infrequent chronic infection regarded as the most misdiagnosed disease by experienced clinicians. The Office of Rare Diseases at the National Institute of Health has also listed this disease as a "rare disease." This article presents a case report of actinomycosis of the alveolus with unusual clinical features but a successful resolution. Read More

    A case of relapsed lung abscess caused byinfection following an initial diagnosis of pulmonary actinomycosis.
    Respir Med Case Rep 2017 17;22:171-174. Epub 2017 Aug 17.
    Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
    We report a rare case of lung abscess due to. In this case, an analysis of the aspirate from frank pus revealed Gram-positive coccobacilli. We initially strongly suspected lung abscess associated with actinomycosis because of the chronic/recurrent clinical course and radio-pathological findings such as a granuloma lesion. Read More

    Surgical treatment of stage 2 medication-related osteonecrosis of the jaw compared to osteomyelitis.
    Cranio 2017 Aug 30:1-8. Epub 2017 Aug 30.
    a Department of Oral and Maxillofacial Surgery , National Health Insurance Service Ilsan Hospital , Goyang , Republic of Korea.
    Objective: To compare the characteristics and outcomes of patients who underwent surgical treatment for stage 2 medication-related osteonecrosis of the jaw (MRONJ) versus osteomyelitis.

    Methods: This retrospective study compared the following variables in 73 patients with stage 2 MRONJ versus 89 patients with osteomyelitis: impaired wound healing after surgery, sex, age, the presence of actinomycosis, location of the jaw lesion, and involvement of the inferior alveolar nerve (IAN).

    Results: There were significant differences between the groups in age, sex, rates of impaired wound healing, actinomycosis, and the location (anterior/posterior) of the lesion. Read More

    Emerging role ofin brain abscesses: A case report and literature review.
    IDCases 2017 20;10:26-29. Epub 2017 Jul 20.
    Yale AIDS Program, New Haven, CT, USA.
    We describe a case of a 29-year-old man from Pakistan who presented with progressive neurologic symptoms over 1 week and was found to have a right parietal cerebral abscess. Neurosurgical drainage cultures showed growth of,, and. An abscessed molar was identified as the likely port of entry and was extracted. Read More

    [Retrospective analysis of 13 cases of nocardiosis].
    Zhonghua Jie He He Hu Xi Za Zhi 2017 Aug;40(8):588-591
    Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
    To evaluate the clinical features, chest radiological manifestations, microbiological examination and treatments of nocardial disease.A retrospective study was conducted to analyze the data of patients with nocardial infection admitted to Beijing Chaoyang Hospital from January 2010 to January 2016.The 13 patients, 6 males and 7 females, aged (51±17) years. Read More

    Pulmonary Actinomycosis in a Patient with AIDS/HCV.
    J Clin Diagn Res 2017 Jun 1;11(6):OD15-OD17. Epub 2017 Jun 1.
    Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis, Tehran, Iran.
    Pulmonary actinomycosis is a rare bacterial lung infection which is caused mainly by Actinomyces israelii. This non contagious infection can destroy parts of the lungs. There are variable presentations of pulmonary actinomycosis with similarity in manifestations to other infectious diseases of the lungs. Read More

    Omental actinomycosis imitating a foreign body infection.
    Z Gastroenterol 2017 Jul 14;55(7):675-678. Epub 2017 Jul 14.
    Actinomycosis is a rare chronic disease caused by a group of anaerobic Gram-positive bacteria that colonize the mouth, colon, and urogenital tract. Infection involving the cervicofacial area is the most common clinical presentation, followed by that of the pelvic and thoracic areas. The preoperative diagnosis of abdominal actinomycosis is difficult because the condition can be easily confused with malignancy, tuberculosis, or other inflammatory diseases. Read More

    Anaplastic large cell lymphoma: A great mimic on cytology.
    J Cytol 2017 Jul-Sep;34(3):165-167
    Department of Pathology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India.
    Anaplastic large cell lymphoma (ALCL) is a T-cell lymphoma, accounting for <5% of non-Hodgkin's lymphoma. Cutaneous involvement can be primary or secondary arising in systemic ALCL. The diagnostic feature in both is the presence of pleomorphic, CD30 positive hallmark cells. Read More

    A Complicated Thread: Abdominal Actinomycosis in a Young Woman with Crohn Disease.
    Case Rep Gastroenterol 2017 May-Aug;11(2):377-381. Epub 2017 Jun 14.
    Minneapolis Veterans Hospital, Minneapolis, Minnesota, USA.
    Crohn disease is a chronic inflammatory condition that primarily affects the gastrointestinal tract. Typical manifestations include fever, weight loss, fatigue, and abdominal pain, and abdominal abscesses and fistulae are frequent complications. Abdominal actinomycosis is a subacute or indolent disease associated withspp. Read More

    [Respiratory infections caused by slow-growing bacteria: Nocardia, Actinomyces, Rhodococcus].
    Rev Mal Respir 2017 Jun 5;34(6):661-671. Epub 2017 Jul 5.
    Service de microbiologie, unité mobile de microbiologie clinique, hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, 20, rue Leblanc, 75015 Paris, France; Université Paris Descartes, 75006 Paris, France. Electronic address:
    Introduction: Pneumonia caused by slow-growing bacteria is rare but sometimes severe.

    State Of The Art: These infections share many similarities such as several differential diagnoses, difficulties to identify the pathogen, the importance of involving the microbiologist in the diagnostic investigation and the need for prolonged antibiotic treatment. However, major differences distinguish them: Nocardia and Rhodococcus infect mainly immunocompromised patients while actinomycosis also concerns immunocompetent patients; the severity of nocardioses is related to their hematogenous spread while locoregional extension by contiguity makes the gravity of actinomycosis. Read More

    Pelvic Actinomycosis.
    Can J Infect Dis Med Microbiol 2017 8;2017:9428650. Epub 2017 Jun 8.
    Coordinación Delegacional de Investigación en Salud, México Poniente, Instituto Mexicano del Seguro Social, Toluca, MEX, Mexico.
    Introduction: Actinomycosis is a chronic bacterial infection caused by, Gram-positive anaerobic bacteria. Its symptomatology imitates some malignant pelvic tumours, tuberculosis, or nocardiosis, causing abscesses and fistulas. Actinomycoses are opportunistic infections and require normal mucous barriers to be altered. Read More

    Actinomycosis Causing Recurrent Perianal Fistulae.
    ACG Case Rep J 2017 21;4:e82. Epub 2017 Jun 21.
    Department of General Surgery, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
    Actinomycosis is a rare but easily curable infection that should be considered in the differential diagnosis of perianal fistulizing disease. We present the case of a 26-year-old woman with complex perianal fistulae, including trans-sphincteric and suprasphincteric fistulous tracts and a rectovaginal fistula, requiring multiple abscess drainages, seton placement, and antibiotic courses, with little improvement. After extensive investigation,. Read More

    Actinomyces radicidentis and Actinomyces haliotis, coccoid Actinomyces species isolated from the human oral cavity.
    Anaerobe 2017 Dec 21;48:19-26. Epub 2017 Jun 21.
    Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
    There are few reports on the bacterial species Actinomyces radicidentis in the literature. In this study, putative A. radicidentis isolates were collected from 16 root canal samples from 601 examined patients. Read More

    Simultaneous UHPLC-UV analysis of hydroxychloroquine, minocycline and doxycycline from serum samples for the therapeutic drug monitoring of Q fever and Whipple's disease.
    J Chromatogr B Analyt Technol Biomed Life Sci 2017 Aug 9;1060:166-172. Epub 2017 Jun 9.
    IHU Mediterranee Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.
    A fast UHPLC-UV method was developed for the simultaneous analysis of Hydroxychloroquine, Minocycline and Doxycycline drugs from 100μL of human serum samples. Serum samples were extracted by liquid-liquid extraction and injected into a phenyl hexyl reverse phase column. Compounds were separated using a mobile phase linear gradient and monitored by UV detection at 343nm. Read More

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