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    Brain abscess caused by chronic invasive actinomycosis in the nasopharynx: A case report and literature review.
    Medicine (Baltimore) 2018 Apr;97(16):e0406
    Department of Otorhinolaryngology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
    Rationale: Actinomycosis is a rare anaerobic, gram-positive bacterial infection caused by Actinomyces, which is part of the normal flora in the oral cavity and respiratory and female genitourinary tracts. The cervicofacial area is the most common site of involvement, and involvement of the central nervous system is rare.

    Patient Concerns: We report a case involving a 51-year-old woman who developed an actinomycotic brain abscess 15 months after the treatment of noninvasive nasopharyngeal actinomycosis, which recurred as an invasive form. Read More

    A cross-sectional survey and follow up study on major dairy health problems in large and small scale urban farms in Mekelle, Tigray, Ethiopia.
    BMC Res Notes 2018 Apr 10;11(1):236. Epub 2018 Apr 10.
    Department of Clinical Studies, College of Veterinary Medicine and Animal Sciences, University of Gondar,, Gondar, Ethiopia.
    Objective: This study was conducted with the objective of estimating the incidence of major dairy health problems in the area.

    Result: From a cross-sectional survey (n = 475) and follow up study (n = 68), an overall incidence of 43.00 and 29. Read More

    Intraabdominal actinomycosis resulting in a difficult to diagnose intraperitoneal mass: A case report.
    Int J Surg Case Rep 2018 Mar 21;45:101-103. Epub 2018 Mar 21.
    Department of Pathology, Kinki Central Hospital, Hyogo, Japan.
    Introduction: Actinomycosis is a chronic suppurative granulomatous disease caused by Actinomyces israelii. Preoperative confirmed diagnosis is very difficult, so most cases are diagnosed preoperatively as malignant tumors. We report a case of intraabdominal actinomycosis which was difficult to diagnose preoperatively. Read More

    Craniofacial osteomyelitis evolving from sinusitis.
    Radiol Case Rep 2018 Feb 20;13(1):104-107. Epub 2017 Dec 20.
    Department of Otolaryngology-Head & Neck Surgery, University of Washington, Seattle, WA, USA.
    Craniofacial osteomyelitis progression is rare, as patients are soon treated. A 56-year-old male smoker presented with sinusitis and was managed medically. This patient failed to follow up and presented 1 year later with erosive bony disease. Read More

    Wolf in Sheep's clothing: Intracranial actinomycosis masquerading as meningioma.
    Surg Neurol Int 2018 14;9:39. Epub 2018 Feb 14.
    Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
    Background: is a gram-positive non-acid-fast bacterium and is the most common causative agent of actinomycosis. It usually presents as a brain abscess via a secondary spread from the cervicofacial region or lungs. However, presentation as an lesion with bone involvement out of proportion to brain parenchyma is rare and needs to be acknowledged. Read More

    Actinomycosis, a lurking threat: a report of 11 cases and literature review.
    Rev Soc Bras Med Trop 2018 Jan-Feb;51(1):7-13
    Infectious Diseases Unit, Medical Department, Hospital Pedro Hispano - Matosinhos Local Health Unit, Matosinhos, Portugal.
    Actinomycosis remains characteristically uncommon, but is still an important cause of morbidity. Its clinical presentation is usually indolent and chronic as slow growing masses that can evolve into fistulae, and for that reason are frequently underdiagnosed. Actinomyces spp is often disregarded clinically and is classified as a colonizing microorganism. Read More

    [Disseminated actinomycosis with central nervous system involvement].
    Rev Chilena Infectol 2017 Dec;34(6):598-602
    Hospital Militar Central Bogotá, Colombia.
    Actinomycosis is very rare, as well as the central nervous system (CNS) condition associated with it, presenting a mortality up to 28%. Its manifestations could be similar to infectious conditions from other etiologies, thus, having a better understanding of the entity increases clinical suspicion and also it can provide a timely treatment. The clinical case of an adult with edema in an upper extremity is presented as a manifestation of thrombophlebitis and an abscessed axillary lesion, in which actinomycetes infection was confirmed. Read More

    Pulmonary actinomycosis mimicking a lung metastasis from esophageal cancer; a case report.
    BMC Pulm Med 2018 Feb 27;18(1):39. Epub 2018 Feb 27.
    Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Syogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
    Background: Actinomycosis is a rare bacterial infection caused by Actinomyces. The symptom of actinomycosis is nonspecific and radiological images present as a slow-progressive mass lesion similarly to malignancies. Thus, it is difficult to distinguish pulmonary actinomycosis from malignancies. Read More

    Nasal Cavity Actinomycosis Mimicking Rhinolith.
    J Craniofac Surg 2018 Feb 14. Epub 2018 Feb 14.
    Department of Otorhinolaryngology and Biomedical Research Institute.
    Actinomycosis is a subacute-to-chronic bacterial infection caused by filamentous, gram-positive, non-acid-fast, anaerobic-to-microaerophilic bacteria. It is characterized by continuous spread, suppurative and granulomatous inflammation, and formation of multiple abscesses and sinus tracts that may discharge sulfur granules. Although the most common clinical forms of actinomycosis are cervicofacial, involvement of the nose and paranasal sinuses are extremely rare. Read More

    Hemolytic anemia due to native valve subacute endocarditis with infection.
    Clin Case Rep 2018 Feb 10;6(2):376-379. Epub 2018 Jan 10.
    Division of Hematology and OncologyDepartment of Internal MedicineMaimonides Medical CenterBrooklynNew YorkUSA.
    This case highlights the importance of considering infectious etiology in the management of hemolytic anemia. Hemolytic anemia associated with infectious endocarditis is rare. Actinomyces endocarditis is a rare occurrence and is very challenging to diagnose given the challenges to culture the organism. Read More

    Osteoma with actinomycosis in a nasal cavity: A case report.
    Medicine (Baltimore) 2017 Dec;96(51):e9376
    Plus I Mi Ko clinic, Suncheon, Chonnam, Korea.
    Rationale: Osteoma with actinomycosis is a very rare disease in the nasal cavity.

    Patient Concerns: We report a case of a 17-year-old female student who presented with nasal obstruction and rhinorrhea for 6 months.

    Diagnoses: The preoperative finding was osteoma covered with yellowish polypoid material. Read More

    Extensive Cutaneous Botryomycosis With Subsequent Development of Nocardia-Positive Wound Cultures.
    J Cutan Med Surg 2018 Jan 1:1203475418755762. Epub 2018 Jan 1.
    2 Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
    Botryomycosis is a rare, chronic granulomatous infection caused by a response to bacteria, most commonly Staphylococcus aureus. Cutaneous manifestations, such as subcutaneous nodules, nonhealing ulcers, or sinus tracks, typically occur following inoculation of bacteria after trauma. Drainage from the skin lesions may contain yellow grains resembling those seen in actinomycosis and nocardiosis. Read More

    Refractory actinomycosis of the humerus.
    SAGE Open Med Case Rep 2018 9;6:2050313X17752852. Epub 2018 Jan 9.
    Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
    Actinomycosis is a chronic, opportunistic infection caused by species, such as . Actinomycosis in long bones is very rare. To the best of our knowledge, isolated primary actinomycosis of the humerus is rarely reported in literature. Read More

    Estimating the proportion of clinically diagnosed infectious and non-infectious animal diseases in Ganta Afeshum woreda, Eastern Tigray zone, Ethiopia.
    BMC Res Notes 2018 Jan 15;11(1):29. Epub 2018 Jan 15.
    Department of Biomedical Sciences, College of Veterinary Medicine and Animal Sciences, The University of Gondar, P.O. Box: 196, Gondar, Ethiopia.
    Objective: This study was performed with the objective of identifying the proportion of emerging and endemic livestock diseases using cross sectional survey.

    Result: A total of 285 clinically diseased animals were presented to a veterinary clinic and diagnosed tentatively based on history, clinical sign, and simple laboratory diagnostics and from the study, actinomycosis (15.83%), mastitis (15%), tick infestation (10%), respiratory diseases (9. Read More

    Neurological and neuropsychological complications in the course of chronic Whipple's disease - case report.
    Psychiatr Pol 2017 Oct 29;51(5):953-961. Epub 2017 Oct 29.
    Katedra i Klinika Neurologii, Wydział Lekarski ŚUM w Katowicach.
    Introduction: Whipple's disease (WD) is a chronic, multisystemic infectious disease caused by Gram-positive bacillus Tropheryma whipplei (T.w.). Read More

    Neurological disease may precede lymphadenopathies in Actinomyces europaeus infection.
    J Infect Public Health 2017 Dec 22. Epub 2017 Dec 22.
    Department of Public Health and Pediatrics, Microbiology and Virology Unit, University of Turin, Italy.
    Actinomyces species are part of the commensal flora of the mucous membranes of the oropharynx, gastrointestinal tract and female genital tract. Actinomyces europaeus is a short, nonmotile, facultative anaerobic rod first described in 1997, susceptible in vitro to a wide range of b-lactam antibiotics which are regarded as first choice. In this report we described the case of A. Read More

    Thoracic Actinomycosis With Infiltration of the Spine: An Oncological Pitfall.
    J Pediatr Hematol Oncol 2017 Dec 12. Epub 2017 Dec 12.
    Pediatric Hematology and Oncology, St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna.
    Thoracic actinomycosis with involvement of the vertebral column and chest wall is rare in children and may resemble malignant tumors. A 12-year-old girl was admitted to our clinic having B-symptoms, cachexia, and painful scoliosis (Karnofsky index 20%). Imaging showed a large thoracic left-sided paravertebral tumor with infiltration of the vertebrae, destruction of the chest wall and multiple intrapulmonary nodules. Read More

    Actinomycosis is not Frequent in the Periapex But is a Persistent Lesion.
    Braz Dent J 2017 Nov-Dec;28(6):688-693
    Dentistry and Health Postgraduate Program, Dental School, UFBA - Universidade Federal da Bahia, Salvador, BA, Brazil.
    Periapical actinomycosis caused by a gram-positive anaerobic pathogen characterizes a typical extra-radicular infection. This study determined the frequency and correlated the content of bacteria colonies with the of periapical actinomycosis size. The study comprised a total of 218 periapical lesions (PL) (cysts, granulomas or abscess). Read More

    [Actinomycosis revealed by ulceration of the palate and gingiva].
    Ann Dermatol Venereol 2018 Mar 28;145(3):173-177. Epub 2017 Nov 28.
    Service de dermatologie, CHU d'Amiens, 1, place Victor-Pauchet, 80000 Amiens, France; Université de Picardie-Jules-Verne, 80000 Amiens, France.
    Background: Actinomycosis is a chronic and extensive granulomatous, bacterial infection. Revelation by oral ulceration is rare.

    Patients And Methods: A 76-year-old patient with diabetes was treated with dabrafenib for stage IV melanoma. Read More

    Transmission electron microscopy helpfulness in Whipple's disease masked by immunosuppressant therapy for arthritis.
    APMIS 2018 Jan 20;126(1):92-96. Epub 2017 Nov 20.
    Section of Pathology, Department of Emergency and Organ Transplantation, University 'Aldo Moro' of Bari, Bari, Italy.
    A 61-year-old woman received a diagnosis of undifferentiated non-erosive arthritis in 2010 and assumed methotrexate and steroids in 2014. After 1 year, she experienced watery diarrhea, vomiting, fever, weight loss, and severe hypoalbuminemia, thus being admitted into our Unit. Esophagogastroduodenoscopy showed duodenal lymphangiectasia and duodenal biopsy samples several foamy PAS-positive macrophages and villous subtotal atrophy. Read More

    A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer.
    Clin J Gastroenterol 2018 Feb 9;11(1):38-41. Epub 2017 Nov 9.
    Department of Gastroenterology, Akita University Graduate School of Medicine, Hondo 1-1-1, Akita, Akita, Japan.
    A 60-year-old man presented with odynophagia after bronchial artery infusion chemotherapy for pulmonary metastasis of hepatocellular carcinoma. Esophagogastroduodenoscopy (EGD) revealed an esophageal ulcer in the middle thoracic esophagus. An esophageal biopsy demonstrated no malignancy. Read More

    A Rare Thermophilic Bug in Complicated Diverticular Abscess.
    Case Rep Gastroenterol 2017 Sep-Dec;11(3):569-575. Epub 2017 Sep 27.
    GI and Hepatology, The Brooklyn Hospital Center, Affiliate of the Mount Sinai Hospital, Brooklyn, New York, USA.
    Actinomycosis is a form of painful abscess in the gastrointestinal tract or in deep tissue caused by actinomyces species. They are one of the commensal bacteria in the oral cavity and gastrointestinal tract of humans but can opportunistically cause infection in immunosuppressive hosts through invasion of breached mucosa or necrotic tissue while mimicking malignancy, gastrointestinal tuberculosis, and inflammatory bowel disease. is, by far, the major and most common human pathogen throughout literatures. Read More

    Granulomatous Thyroiditis: A Case Report and Literature Review.
    Ann Clin Lab Sci 2017 Sep;47(5):620-624
    Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
    Background: Granulomatous disease in the thyroid gland has been linked to viral, bacterial and autoimmune etiologies. The most common granulomatous disease of the thyroid is subacute granulomatous thyroiditis, which is presumed to have a viral or post-viral inflammatory cause. Bacterial etiologies include tuberculosis, actinomycosis, and nocardiosis, but are extremely rare. Read More

    Cervical precancerous changes and selected cervical microbial infections, Kiambu County, Kenya, 2014: a cross sectional study.
    BMC Infect Dis 2017 09 25;17(1):647. Epub 2017 Sep 25.
    Department of Medical Laboratory Sciences, Kenyatta University, School of Medicine, P. O. Box 43844-00100, Nairobi, Kenya.
    Background: Cervical cancer is the predominant cancer among women in Kenya and second most common in women in developing regions. Population-based cytological screening and early treatment reduces morbidity and mortality associated with the cancer. We determined the occurrence of cervical precancerous changes and cervical microbial infections (Trichomonas vaginalis, Candida albicans, Neisseria gonorrhea and Actinomyces) among women attending Family Health Option Kenya (FHOK) clinic in Thika. Read More

    A rare coexistence of aspergillosis with actinomycosis.
    J Oral Maxillofac Pathol 2017 May-Aug;21(2):277-281
    Department of Oral and Maxillofacial Pathology, GSL Dental College, Rajahmundry, Andhra Pradesh, India.
    Aspergillosis is a common systemic mycosis which affects immunocompromised and immunocompetent hosts. spp. is wide spread in the environment in most countries, which renders an invasive form of disease. Read More

    Retroperitoneal Actinomycosis: A Rare Sequela of an Infected Obstructing Ureteral Stone.
    J Endourol Case Rep 2017 1;3(1):93-96. Epub 2017 Jul 1.
    Department of Urology, University of Minnesota Medical School, Minneapolis, Minnesota.
    Actinomycosis is a condition in which , a normal component of the oral and gastrointenstial flora, becomes pathogenic in the setting of damaged tissue, leading to widespread tissue destruction across fascial planes. Prior literature describing this condition is rare, particularly cases involving the retroperitoneum. In this study, we report a case of retroperitoneal actinomycosis caused by an infected, obstructing ureteral stone. Read More

    Pulmonary actinomycosis masquerading as lung cancer: A case report.
    Med J Malaysia 2017 Aug;72(4):246-247
    Hospital Sultanah Nora Ismail, Department of Medicine, Batu Pahat, Johor, Malaysia.
    Pulmonary actinomycosis is a rare yet important and challenging diagnosis to make. It is commonly confused with other lung diseases, such as tuberculosis and bronchogenic carcinoma, leading to delay diagnosis or misdiagnosis. A 49-year-old man presented with a chronic cough, hemoptysis, and pleuritic chest pain. Read More

    The cytopathology of Actinomyces, Nocardia, and their mimickers.
    Diagn Cytopathol 2017 Dec 9;45(12):1105-1115. Epub 2017 Sep 9.
    Department of Pathology, Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio, 44106.
    Nocardia species and Actinomyces species are 2 of the most commonly diagnosed filamentous bacteria in routine cytopathology practice. These genera share many overlapping cytomorphologic features, including their thin, beaded, branching, Gram-positive, GMS-positive filamentous structures that fragment at their peripheries into bacillary- and coccoid-appearing forms. Features that help distinguish between these 2 microorganisms include the width of their filamentous structures, the angles at which they branch, and their ability or lack thereof to retain a modified acid-fast stain. Read More

    A rare case of empyema: Still a challenging entity to manage.
    Respir Med Case Rep 2017 12;22:203-205. Epub 2017 Aug 12.
    Pneumology in Thorax Department, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.
    is a rare pathogen and an infrequent cause of human actinomycosis. Less than ten cases were reported in the English-literature to date concerning empyema. We herein report a case to promote the awareness and adequate management of the disease. Read More

    Actinomycosis of the foot - A South African case.
    S Afr J Surg 2017 Jun;55(2):36
    Department of Surgery, Livingstone Hospital, Walter Sisulu University (WSU).
    Mycetoma is a chronic infection, characterised by severe disability and discomfort to patients. This condition is common throughout tropical regions of the world. The Indian subcontinent and north-east Africa, especially Sudan, bear the majority of the disease burden. Read More

    Actinomyces: a deceptive infection of oral cavity.
    J Korean Assoc Oral Maxillofac Surg 2017 Aug 24;43(4):282-285. Epub 2017 Aug 24.
    Department of Prosthodontics, Crown and Bridges, RKDF Dental College, Bhopal, India.
    Actinomycosis is an infrequent chronic infection regarded as the most misdiagnosed disease by experienced clinicians. The Office of Rare Diseases at the National Institute of Health has also listed this disease as a "rare disease." This article presents a case report of actinomycosis of the alveolus with unusual clinical features but a successful resolution. Read More

    A case of relapsed lung abscess caused by infection following an initial diagnosis of pulmonary actinomycosis.
    Respir Med Case Rep 2017 17;22:171-174. Epub 2017 Aug 17.
    Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
    We report a rare case of lung abscess due to . In this case, an analysis of the aspirate from frank pus revealed Gram-positive coccobacilli. We initially strongly suspected lung abscess associated with actinomycosis because of the chronic/recurrent clinical course and radio-pathological findings such as a granuloma lesion. Read More

    Surgical treatment of stage 2 medication-related osteonecrosis of the jaw compared to osteomyelitis.
    Cranio 2017 Aug 30:1-8. Epub 2017 Aug 30.
    a Department of Oral and Maxillofacial Surgery , National Health Insurance Service Ilsan Hospital , Goyang , Republic of Korea.
    Objective: To compare the characteristics and outcomes of patients who underwent surgical treatment for stage 2 medication-related osteonecrosis of the jaw (MRONJ) versus osteomyelitis.

    Methods: This retrospective study compared the following variables in 73 patients with stage 2 MRONJ versus 89 patients with osteomyelitis: impaired wound healing after surgery, sex, age, the presence of actinomycosis, location of the jaw lesion, and involvement of the inferior alveolar nerve (IAN).

    Results: There were significant differences between the groups in age, sex, rates of impaired wound healing, actinomycosis, and the location (anterior/posterior) of the lesion. Read More

    Emerging role of in brain abscesses: A case report and literature review.
    IDCases 2017 20;10:26-29. Epub 2017 Jul 20.
    Yale AIDS Program, New Haven, CT, USA.
    We describe a case of a 29-year-old man from Pakistan who presented with progressive neurologic symptoms over 1 week and was found to have a right parietal cerebral abscess. Neurosurgical drainage cultures showed growth of , , and . An abscessed molar was identified as the likely port of entry and was extracted. Read More

    [Retrospective analysis of 13 cases of nocardiosis].
    Zhonghua Jie He He Hu Xi Za Zhi 2017 Aug;40(8):588-591
    Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
    To evaluate the clinical features, chest radiological manifestations, microbiological examination and treatments of nocardial disease. A retrospective study was conducted to analyze the data of patients with nocardial infection admitted to Beijing Chaoyang Hospital from January 2010 to January 2016. The 13 patients, 6 males and 7 females, aged (51±17) years. Read More

    Pulmonary Actinomycosis in a Patient with AIDS/HCV.
    J Clin Diagn Res 2017 Jun 1;11(6):OD15-OD17. Epub 2017 Jun 1.
    Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis, Tehran, Iran.
    Pulmonary actinomycosis is a rare bacterial lung infection which is caused mainly by Actinomyces israelii. This non contagious infection can destroy parts of the lungs. There are variable presentations of pulmonary actinomycosis with similarity in manifestations to other infectious diseases of the lungs. Read More

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