Expression of E-cadherin, syndecan 1, Ki-67, and maintenance minichromosome 3 in tissue lesions of actinic prurigo obtained by incisional biopsy.
- Alexandra Mancheno-Valencia,
- Ronell Eduardo Bologna-Molina,
- Sonia Toussaint-Caire,
- María Elisa Vega-Memije,
- Juan Carlos Cuevas-González
Indian J Pathol Microbiol 2018 Apr-Jun;61(2):225-227
Department of Stomatology, Institute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Chihuahua, Mexico.
Actinic prurigo (AP) is an idiopathic photodermatosis; the initial manifestations usually occur during the first decades of life but can appear at any age. Cases are usually diagnosed late once the lesions have exacerbated; due to the extensive involvement of the vermilion border and the etiology, it has been confused with and related to a potentially malignant process. Syndecan-1 and E-cadherin were positive in the epidermis, with moderate-to-intense staining in 100% of samples. Read More