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    4929 results match your criteria Actas dermo-sifiliograficas[Journal]

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    Photocarcinogenic Risk Associated With Narrowband UV-B Phototherapy: An Epidemiologic Study in a Tertiary Care Hospital.
    Actas Dermosifiliogr 2018 Feb 17. Epub 2018 Feb 17.
    Hospital General Universitario de Valencia. Servicio de Dermatología.
    Background: The risk of skin cancer in patients treated with narrowband (NB) UV-B phototherapy is not well understood. Although experimental studies have shown that there is a risk, clinical studies have not detected an increased incidence of cancer following treatment. The aim of this study was to determine the incidence of nonmelanoma skin cancer (NMSC) in patients treated with NB UV-B phototherapy at a tertiary care hospital in the Mediterranean area. Read More

    Dermatology and Immunoglobulin Therapy: Who to Treat and How to Administer Immunoglobulins.
    Actas Dermosifiliogr 2018 Feb 8. Epub 2018 Feb 8.
    Unidad de Gestión Clínica de Dermatología y Venereología, Complejo Hospitalario Universitario de Granada, Granada, España.
    Intravenous immunoglobulin (IVIG) replacement therapy has been used in immune deficiency diseases for more than 50 years. The indications for this treatment have evolved, however, and IVIG therapy is now used in various diseases in which the immune system plays a prominent role. IVIG therapy has carved out a niche in dermatology for the treatment of such conditions as dermatomyositis, autoimmune bullous diseases, and toxic epidermal necrolysis. Read More

    Mucocutaneous Manifestations of Infection by Histoplasma capsulatum in HIV-Negative Immunosuppressed Patients.
    Actas Dermosifiliogr 2018 Feb 8. Epub 2018 Feb 8.
    Servicio de Dermatología, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
    Histoplasmosis is a systemic mycosis caused by the dimorphous fungus Histoplasma capsulatum (H. capsulatum). The fungus enters the body through the respiratory tract in the form of microconidia, which are transformed into intracellular yeast-like structures in the lungs before disseminating hematogenously. Read More

    Dupilumab for the Treatment of Atopic Dermatitis.
    Actas Dermosifiliogr 2018 Feb 5. Epub 2018 Feb 5.
    Unidad de Dermatología, Centro Hospitalar Universitário do Porto, Oporto, Portugal; Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Oporto, Portugal. Electronic address:
    Atopic dermatitis (AD) is a common, chronic, inflammatory skin disorder with high physical and emotional burden. AD usually starts in early childhood and has a heterogeneous course. Emerging evidence suggests that IL-4 and IL-13 are key cytokines in the immunopathogenesis of AD. Read More

    Blisters Induced by PUVA: A Report of 5 Cases.
    Actas Dermosifiliogr 2018 Feb 1. Epub 2018 Feb 1.
    Servicio de Dermatología, Hospital Universitario de Cabueñes, Gijón, Asturias, España.
    Blisters associated with PUVA treatments are an adverse effect of photochemotherapy that has been reported in the literature. Asymptomatic blisters appear spontaneously mainly on the lower limbs and resolve without treatment. The differential diagnoses to consider include a phototoxic reaction, pseudoporphyria, and PUVA-induced bullous pemphigoid. Read More

    Description of patients excluded for Mohs surgery after pre-surgical evaluation: data from the Regesmohs Spanish registry.
    Actas Dermosifiliogr 2018 Jan 17. Epub 2018 Jan 17.
    Clínica Universidad de Navarra, Pamplona, España.
    Background: Regesmohs registry is a nationwide registry including patients evaluated for Mohs surgery in 17 Spanish centres since July 2013. Given that Mohs surgery is the therapy with best results for high risk basal cell carcinoma (BCC) and other skin tumours, we wanted to describe the reasons that lead to some patients being excluded from this therapy and the alternative treatments that they received. These data may be useful to avoid excluding patients for Mohs surgery use, to estimate the healthcare demand of these patients and the demand for Hedgehog inhibitors therapy in this group. Read More

    Gorlin Syndrome.
    Actas Dermosifiliogr 2018 Jan 17. Epub 2018 Jan 17.
    Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, España; Departamento de Dermatología, Hospital Clínico Universitario, Salamanca, España.
    Gorlin syndrome is a rare autosomal dominant disease caused by mutations in the sonic hedgehog signaling pathway. Of particular importance is the PTCH1 gene. The disease is characterized by the development of multiple basal cell carcinomas at young ages. Read More

    HIV-Associated Psoriasis.
    Actas Dermosifiliogr 2018 Jan 17. Epub 2018 Jan 17.
    Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto, Portugal; Unidad de Dermatología, Centro Hospitalar e Universitário do Porto, Porto, Portugal. Electronic address:
    Human immunodeficiency virus (HIV) prevalence is increasing worldwide as people on antiretroviral therapy are living longer. These patients are often susceptible to debilitating inflammatory disorders that are frequently refractory to standard treatment. Psoriasis is a systemic inflammatory disorder, associated with both physical and psychological burden, and can be the presenting feature of HIV infection. Read More

    Photodynamic Therapy Interventions in Facial Photodamage: A Systematic Review.
    Actas Dermosifiliogr 2017 Dec 30. Epub 2017 Dec 30.
    Grupo de Investigación Dermatológica (GRID), Universidad de Antioquia, Medellín, Colombia.
    Introduction: Photodynamic therapy (PDT) involves the combination of a light source and a photosensitizing agent to induce tissue damage via the generation of singlet oxygen. Although topical PDT has been approved for other indications, its use in facial photodamage is uncertain.

    Aims: To assess the efficacy and safety of PDT in facial skin photoaging. Read More

    Sclerodermatous Chronic Graft-versus-Host Disease Treated With Imatinib: A Dermatological Perspective.
    Actas Dermosifiliogr 2017 Dec 15. Epub 2017 Dec 15.
    Unidad de Dermatología, Hospital Universitario y Politécnico La Fe, Valencia, España; Grupo de Investigación de Dermatología y Regeneración Tisular, Hospital Universitario y Politécnico La Fe, Valencia, España.
    Introduction: Chronic graft-versus-host disease (cGVHD) is the most important cause of late non-relapse mortality after allogeneic hematopoietic stem cell transplantation. Sclerodermatous cGVHD is usually steroid refractory and remains a therapeutic challenge. Activating antibodies against the PDGFR have been reported in patients with sclerodermatous cGVHD. Read More

    Reconstructive methods in Mohs micrographic surgery in Uruguay: A bidirectional descriptive cohort analysis.
    Actas Dermosifiliogr 2017 Dec 14. Epub 2017 Dec 14.
    Cátedra de Dermatología Prof. Dr. Miguel Martínez, Hospital de Clínicas Dr. Manuel Quintela, Universidad de la República, Montevideo, Uruguay.
    Background And Objectives: The primary goal of Mohs micrographic surgery (MMS) is to completely excise a cancerous lesion and a wide range of reconstructive techniques of varying complexity are used to close the resulting wound. In this study, we performed a descriptive analysis of patients who underwent MMS, with a focus on wound closure methods.

    Material And Methods: We conducted a bidirectional descriptive cohort analysis of all MMS procedures performed by a single surgeon between November 2013 and April 2016. Read More

    Morphea in Childhood: An Update.
    Actas Dermosifiliogr 2017 Dec 13. Epub 2017 Dec 13.
    Servicio de Dermatología, Hospital Universitario Infanta Cristina , Parla, Madrid, España.
    Morphea is an inflammatory, fibrosing skin disorder. When it occurs in childhood, it is also known as localized juvenile scleroderma. It is more common in girls and typically appears around the age of 5 to 7 years. Read More

    A 12-Day Course of Imiquimod 5% for the Treatment of Actinic Keratosis: Effectiveness and Local Reactions.
    Actas Dermosifiliogr 2017 Dec 12. Epub 2017 Dec 12.
    Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España; Departamento de Piel y Órganos de los Sentidos, Facultad de Medicina, Universidad CEU Cardenal Herrera, Valencia, España.
    Introduction And Objectives: Imiquimod is an excellent option for patients with actinic keratosis, although its use may be limited by the long course of treatment required (4 weeks) and the likelihood of local skin reactions. The objectives of the present study were to demonstrate the effectiveness of a 12-day course of imiquimod 5% for the treatment of actinic keratosis and to examine the association between treatment effectiveness and severity of local reactions.

    Patients And Methods: We included patients with at least 8 actinic keratoses treated with imiquimod 5% cream for 12 consecutive days. Read More

    Clinical research at territorial section meetings of the Spanish Academy of Dermatology and Venereology (AEDV).
    Actas Dermosifiliogr 2017 Dec 6. Epub 2017 Dec 6.
    Servicio de Dermatología, Complejo Hospitalario Universitario de Pontevedra, EOXI Pontevedra-Salnés, Pontevedra, España.
    Introduction: Clinical research is the study of patients with the aim of improving care. Our objectives were to calculate the percentage of presentations at territorial section meetings of the Spanish Academy of Dermatology and Venereology (AEDV) that described clinical research, to assess the level of evidence the research provided, and to analyze change in clinical research volume over time.

    Material And Methods: We reviewed supplements of the journal Actas Dermo-Sifiliográficas for 2000 through 2015 that contained abstracts of presentations given at the AEDV section meetings in Galicia; the area comprising Asturias, Cantabria, and Castile-Leon (ACCL); and Andalusia. Read More

    Pitiryasis Lichenoides et Varioliformis Aacuta Associated With Human Herpesvirus 7.
    Actas Dermosifiliogr 2017 Dec 5. Epub 2017 Dec 5.
    Unidad de Dermatología y Venereología, Centro Hospitalario São João, EPE, Oporto, Portugal.
    Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica represent 2 ends of a disease spectrum of unknown etiology. Herein we describe 2 cases of pityriasis lichenoides et varioliformis acuta, in which human herpesvirus 7 DNA was detected in skin samples by polymerase chain reaction methodology, an association not previously described. This report may support the involvement of viral infection in the etiopathogeny of this disease. Read More

    Idiopathic Facial Aseptic Granuloma: Clinical and Ultrasound Findings in 3 Cases.
    Actas Dermosifiliogr 2017 Dec 4. Epub 2017 Dec 4.
    Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.
    Idiopathic facial aseptic granuloma is a typical childhood disease characterized by the presence of one or more asymptomatic nodules on the cheek. Although pathogenesis remains unclear, the disease is thought to be a type of childhood rosacea. It resolves spontaneously, yet it could be confused with other lesions that require treatment. Read More

    Atypical Presentation of Herpes Simplex Virus Type 2 Infection Refractory to Treatment With Acyclovir in 2 Hematologic Patients.
    Actas Dermosifiliogr 2017 Dec 1. Epub 2017 Dec 1.
    Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.
    Herpesvirus infections are not uncommon in hematologic patients. Our first patient, diagnosed with chronic lymphatic leukemia, presented extensive genital herpes infection refractory to treatment with acyclovir and with a partial response to foscarnet, which had to be withdrawn due to systemic adverse effects. The second patient, diagnosed with follicular Hodgkin lymphoma, presented hypertrophic herpes infection refractory to treatment with acyclovir but that responded to intralesional cidofovir and topical imiquimod. Read More

    Recessive Dystrophic Epidermolysis Bullosa and Pregnancy.
    Actas Dermosifiliogr 2017 Dec 1. Epub 2017 Dec 1.
    Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.
    Dystrophic epidermolysis bullosa is a rare inherited disease caused by mutations in the COL7A1 gene. Its recessive variant (recessive dystrophic epidermolysis bullosa) is characterized by the absence or considerably reduced expression of type VII collagen, which leads to marked fragility of the skin and mucous membranes and subsequent blister formation, whether spontaneously or following minimal injury. There have been very few reports of this disease in pregnant women. Read More

    Diagnostic Tools to Use When We Suspect an Allergic Reaction to a Tattoo: A Proposal Based on Cases at Our Hospital.
    Actas Dermosifiliogr 2017 Dec 6. Epub 2017 Dec 6.
    Unidad de Alergia Cutánea, Servicio de Dermatología, Hospital General Universitario de Alicante - ISABIAL, Alicante, España.
    Introduction: Tattooing has become a popular practice in western countries, particularly among younger populations. Tattoos, however, can cause complications, such as infections, allergic or foreign-body reactions, and even systemic inflammatory responses.

    Patients And Methods: We conducted a retrospective study of all patients seen for tattoo-related complications at our skin allergy unit between January 2002 and December 2016. Read More

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