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Actas Urol Esp 2018 Jun 20. Epub 2018 Jun 20.

Servicio de Urología, Complejo Hospitalario Universitario de Granada, Granada, España.

Objective: To put forth new findings of urologic oncology with impact on clinical practice presented during 2017 in the main annual meetings.

Methods: This document reviews abstracts on prostate, kidney and bladder cancer presented at the congresses of 2016 (EAU, AUA, ASCO, ESMO and ASTRO) and publications with the highest impact in this period valued with the highest scores by the OncoForum committee.

Results: Among patients at high risk of recurrent renal cell carcinoma after nephrectomy, adjuvant sunitinib compared to placebo showed a benefit in patients at higher risk of recurrence. Read More

Actas Urol Esp 2018 Jun 18. Epub 2018 Jun 18.

Centro Hospitalar São João, Oporto, Portugal.

Objectives: Feasibility study to evaluate efficacy and safety of Adjustable Transobturator Male System (ATOMS) for male stress urinary incontinence (SUI) after transurethral resection of the prostate.

Materials And Methods: Twenty patients were implanted ATOMS for SUI caused by transurethral resection of the prostate with or without radiotherapy. Incontinence severity was evaluated as mild (2 pads/day), moderate (3-5 pads/day) or severe (≥6pads/day), and dryness as none or one security pad/day. Read More

Actas Urol Esp 2018 Jun 15. Epub 2018 Jun 15.

Unidad del Dolor, Hospital Don Benito-Villanueva de la Serena, Don Benito, Badajoz, España.

Actas Urol Esp 2018 Jun 12. Epub 2018 Jun 12.

University Medical Centre, Utrecht, The Netherlands.

The standardisation working group of the International Continence Society has updated the Good Urodynamic Practice directives. This evidence-based ICS-GUP2016 has defined the terminology and standards of Urodynamic practice, for the laboratory and for individual practice, in quality control during cystometry and pressure-flow analysis. In addition, the working group included recommendations prior to the test and information about how to prepare the patient, as well as recommendations for the reporting of urodynamics. Read More

Actas Urol Esp 2018 Jun 11. Epub 2018 Jun 11.

Unidad de Urología Oncológica, Departamento de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Actas Urol Esp 2018 Jun 10. Epub 2018 Jun 10.

Department of Surgery, Oncology and Gastroenterology, Urology, University of Padova, Padua, Italia. Electronic address:

Actas Urol Esp 2018 Jun 8. Epub 2018 Jun 8.

Grupo Español de Cáncer de Próstata, Madrid, España.

Aims: To describe the 3-year progression-free survival (PFS), overall survival (OS) and disease-specific mortality in the prospective prostate cancer GESCAP cohort, as well as the progression to castration resistance in patients on hormone therapy.

Material And Methods: Prospective, observational, epidemiological, multicentre study. Of the 4087 patients recruited, 3843 were evaluable. Read More

Actas Urol Esp 2018 Jun 7. Epub 2018 Jun 7.

Departamento de Urología pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction: ureteral stump syndrome is defined as a recurrent urinary infection, low abdominal pain and haematuria in patients with a history of nephrectomy. Its incidence is low and the symptoms are non-specific. The aim of our paper was to present our results with endoscopic treatment of symptomatic ureteral remnants. Read More

Actas Urol Esp 2018 Jun 1. Epub 2018 Jun 1.

Unidad Urología Oncológica, Departamento de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Context: Writing skills and the importance of drafting quality are often disregarded. Just as there are guidelines on what each part of a scientific article should comprise (introduction, material and methods, results and conclusion), there are 'norms' as to how to draft the article. Novel results can only be appropriately reflected in a formal and structurally correct text. Read More

Actas Urol Esp 2018 May 23. Epub 2018 May 23.

Director de Actas Urológicas Españolas. Electronic address:

Actas Urol Esp 2018 May 17. Epub 2018 May 17.

Servicio de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Context: A correctly drafted original article gives information on what was done, why it was done, how it was done, the result of what was done, and the significance of what was done. Many articles fail to report their results effectively.

Objective: To describe the characteristics of an original article and to give practical recommendations to prevent the most common errors in our environment. Read More

Actas Urol Esp 2018 May 15. Epub 2018 May 15.

Departamento de Urología, Complexo Hospitalario Universitario de Ourense, Ourense, España.

Actas Urol Esp 2018 May 14. Epub 2018 May 14.

Grupo Español para el Tratamiento del Cáncer Renal (GECARE).

Actas Urol Esp 2018 May 11. Epub 2018 May 11.

Oficina de Historia de la Asociación Española de Urología, Madrid, España. Electronic address:

Introduction And Objectives: We researched the start of urological specialisation in Spain, from the end of the 19th century to the institution of the education system (resident medical intern) to learn about the centres and individuals who created the urological teaching units and training schools in which the first Spanish urologists specialised their training.

Material And Methods: We extracted the references from books on the history of urology, from periodic urological publications and from the posters on history submitted to the congresses of the Spanish Urological Association and filled in the data and dates with the Historical Dictionary of Spanish Urologists.

Result: There are 30 urological specialization centres, 8 with official accreditation recognised by the corresponding ministry but whose official status is unknown. Read More

Actas Urol Esp 2018 May 3. Epub 2018 May 3.

Hospital Clínic, Barcelona, España; EAU Guidelines Office Board Member.

Context: The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the top of the levels-of-evidence pyramid.

Acquisition Of Evidence: The review process should be well developed and planned to reduce biases and eliminate irrelevant and low-quality studies. Read More

Actas Urol Esp 2018 Apr 23. Epub 2018 Apr 23.

Departamento de Urología, Universidad Estatal de Campinas (UNICAMP), São Paulo, Brasil.

Objectives: To explore the proportion of patients with higher risk localized prostate cancer (PCa) that would become safely biopsy negative 12 months after non-thermal focal therapy with padeliporfin vascular-targeted photodynamic therapy (VTP).

Methods: Multicenter study in a scenario of prostate-specific antigen (PSA) ≤20ng/ml and variable PCa target volumes Gleason pattern 3 or low-volume secondary Gleason pattern 4, all patients received VTP, consisting of intravenous 4mg/kg padeliporfin activated by light-diffusing fibers in the prostate. The prostate was biopsied at baseline, months 6 and 12, PSA, patient-reported functional outcomes and quality of life (QoL) questionnaires were recorded at baseline, months 3, 6, and 12 and adverse events (AE) throughout the study. Read More

Actas Urol Esp 2018 Apr 23. Epub 2018 Apr 23.

Servicio de Urología, Hospital Universitario Donostia, Donostia-San Sebastián, Guipúzcoa, España.

Background: Renal cell carcinoma has a natural tendency to extend through the renal vein. When the thrombus reaches the vena cava, thrombectomy and the necessary reconstruction of the vena cava are typically performed by open pathway. Robot-assisted technology provides advantages for performing this complex technique, using a minimally invasive access. Read More

Actas Urol Esp 2018 Apr 20. Epub 2018 Apr 20.

Hospital Universitario Dr. Peset, Valencia, España.

Background: The intravesical administration of hazardous drug products is a standard practice in the urology setting, which potentially exposing medical personnel to these drug products. It was deemed necessary to have a consensus document among the scientific societies involved (the Spanish Urological Association and the Spanish Society of Hospital Pharmacy) that collects the best available evidence on the safest handling possible of dangerous drug products in the setting of urology departments.

Methods: We reviewed the legislation and recommendations on the handling of dangerous drug products, both at the national and international level. Read More

Actas Urol Esp 2018 Apr 17. Epub 2018 Apr 17.

Unidad de Litiasis, Servicio de Urología, Fundacio Puigvert, Barcelona, España.

Introduction: There are currently 3holmium laser, YAG (Ho:YAG) endolithotripsy procedures that are considered basic (fragmentation, pulverisation, "pop-corn" technique). We present the technique of fragmentation targeted at preferred discontinuities (FTPD), a new concept of endolithotripsy by Ho:YAG laser.

Material And Methods: The FTPD technique is based on the selective application of energy (targeting a specific preselected point) to an area that is visually prone to the formation of a fracture line or preferred discontinuity (conditioned by the anisotropy of the urolithiasis). Read More

Actas Urol Esp 2018 Apr 13. Epub 2018 Apr 13.

Servicio de Urología, Hospital Universitario Fundación Alcorcón, Madrid, España.

Background: Our main objective was to report the current use of active surveillance in Spain and to identify areas for potential improvement.

Methods: A questionnaire generated by the Platform for Multicentre Studies of the Spanish Urology Association (AEU/PIEM/2014/0001, NCT02865330) was sent to all associate researchers from January to March 2016. The questionnaire included 7 domains covering various aspects of active surveillance. Read More

Actas Urol Esp 2018 Apr 10. Epub 2018 Apr 10.

Centro de Urología, Las Palmas de Gran Canaria, España.

Introduction: In 1943, the brothers Alfonso and Emilio de la Peña Pineda proposed creating a communication system by correspondence as in North America, an idea welcomed by Spanish urologists, a system that was named the Urology Exchange by Correspondence.

Material And Methods: A thorough reading and detailed analysis was conducted of content from 1944 to 1953, with an average of 3 pages of folio size of each copy.

Result: A total of 105 issues containing 234 urological presentations were sent, signed by 67 Spanish urologists, 2 Portuguese urologists and 1 general surgeon. Read More

Actas Urol Esp 2018 Apr 9. Epub 2018 Apr 9.

Health Economics & Outcomes Research. Real-World Evidence Solutions. QuintilesIMS, Barcelona, España.

Objectives: Validation of the Spanish version of the Bladder Pain/Interstitial Cystitis-Symptom Score (BPIC-SS) questionnaire to evaluate its utility for the diagnosis of Bladder Pain Syndrome (BPS) patients in the Female and Urodynamics Urology Functional Units in Spain.

Material And Methods: The Spanish adaptation of the BPIC-SS questionnaire was evaluated in 243 BPS patients. EQ-5D-5L, Patient Perception of Bladder Condition (PPBC) and global impression questionnaire (CGI-S) were collected. Read More

Actas Urol Esp 2018 Apr 9. Epub 2018 Apr 9.

Servicio de Urología, Hospital Comarcal Don Benito-Villanueva de la Serena, Don Benito, Badajoz, España.

Actas Urol Esp 2018 Apr 8. Epub 2018 Apr 8.

Servicio de Urología, Hospital Universitario de Getafe, Madrid, España; Departamento Clínico, Facultad de Ciencias Biomédicas, Universidad Europea de Madrid, Laureate Universities, Getafe, Madrid, España. Electronic address:

Introduction: Stress urinary incontinence (SUI) is a significant sequela of prostate cancer surgery. In this article, we present the surgical technique and safety and efficacy of the adjustable transobturator male system (ATOMS®) with preattached scrotal port.

Material And Method: An open prospective study was conducted at a university hospital with the main objective of changing the baseline condition after adjustment in the daily pad count and their wet weight (pad test). Read More

Actas Urol Esp 2018 Apr 6. Epub 2018 Apr 6.

Servicio de Urología, Hospital Clínico Universitario de Valencia, Facultat de Medicina i Odontologia, Universitat de València, Valencia, España.

Introduction: To study the relationship between quantitative mRNA determination (hTERT) in patients with bladder tumor, history of bladder tumor, and in subjects without a history of this neoplasia.

Material And Methods: A prospective randomized controlled study with 91 subjects included. The value of mRNA-hTERT was determined in 63 patients with a history or suspicion of bladder tumor and in 28 controls. Read More

Actas Urol Esp 2018 Apr 6. Epub 2018 Apr 6.

Anatomía Patológica, Instituto Valenciano de Oncología, Valencia, España.

Objectives: To analyse the most relevant oncologic results of treatment using radical prostatectomy (RP) for high-risk prostate cancer (HRPC) in a specialist cancer hospital.

Material And Methods: A descriptive retrospective study of RP was conducted at our centre from 1986 to 2017 on HRPC whose primary objective was to determine overall survival (OS) and cancer-specific survival (CSS). The study's secondary objectives were to determine biochemical progression-free survival (BPFS), metastasis-free survival (MFS), rescue therapy-free survival (RTFS), hormone therapy-free survival (HTFS) and the development of castration-resistant prostate cancer. Read More

Actas Urol Esp 2018 Apr 6. Epub 2018 Apr 6.

Unidad de Tumores Renales con Afectación Venosa (TRAV), Servicio de Urología, H.G.U. Gregorio Marañón, Madrid, España.

Background And Objective: Surgery on renal tumours with venous thrombosis suffers a high rate of complications and non-negligible perioperative mortality. Our objective was to analyse the postoperative complications, their relationship with the level of the thrombus and its potential predisposing factors.

Materials And Methods: A retrospective analysis was conducted of 101 patients with renal tumours with venous thrombosis operated on between 1988 and 2017. Read More

Actas Urol Esp 2018 Mar 30. Epub 2018 Mar 30.

MRC Centre for Transplantation, King's College London, Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, King's Health Partners, Londres, Reino Unido. Electronic address:

Introduction: Laparoscopic radical nephrectomy(LRN) is a cornerstone in managing renal cancer and small renal masses. Twenty-first century surgical training faces challenges, thus must be efficient and safe so surgeons attain relevant skills, protecting patients and operative outcomes. This study aimed to systematically develop a tool for training and assessment in LRN and validate the developed tool for use by trainee urologists. Read More

Actas Urol Esp 2018 Mar 30. Epub 2018 Mar 30.

Servicio de Urología, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España.

Background: The aim of this study was to report our centre's experience over the past 15 years with patients with lung carcinoma and adrenal metastases treated sequentially with lung resection and adrenalectomy.

Patients And Methods: We analysed a retrospective series of 19 patients who underwent adrenalectomy for lung carcinoma metastasis. All patients were operated on at the same centre, between October 2000 and October 2015. Read More

Actas Urol Esp 2018 Mar 30. Epub 2018 Mar 30.

Servicio de Urología, Institut Mutualiste Montsouris, Université Paris-Descartes, París, Francia.

Objective: To determine the predictors of early, intermediate and late biochemical recurrence (BR) following minimally invasive radical prostatectomy in patients with localised prostate cancer (PC).

Material And Methods: We included 6195 patients with cT1-3N0M0 prostate cancer treated using radical laparoscopic prostatectomy (RLP) and radical robot-assisted prostatectomy at our institution between 2000 and 2016. None of the patients underwent adjuvant therapy. Read More

Actas Urol Esp 2018 Mar 22. Epub 2018 Mar 22.

Servicio de Urología, Hospital Universitario de Cabueñes, Gijón, Asturias, España.

Background: The ureteral disinsertion with bladder cuff technique continues to evolve. We present the endoscopic laser transurethral technique combined with a transperitoneal and retroperitoneal laparoscopic approach in lateral decubitus, without patient repositioning, for treating urothelial carcinomas of the upper urinary tract.

Materials And Methods: We present 3 laparoscopic nephroureterectomies: 1 transperitoneal and 2 retroperitoneal. Read More

Actas Urol Esp 2018 Mar 21. Epub 2018 Mar 21.

Hospital General Universitario de Valencia, Valencia, España.

Introduction: The treatment of localised prostate cancer seeks to minimise the impact on sexual function and urinary continence. In this respect, therapy with high-intensity focused ultrasound offers important results. We present our experience with this technique in 2 Spanish centres. Read More

Actas Urol Esp 2018 Jun 9;42(5):344-349. Epub 2018 Mar 9.

Servicio de Urología, Hospital Universitario Rey Juan Carlos, Universidad Rey Juan Carlos, Móstoles, Madrid, España.

Introduction: Pudendal nerve entrapment syndrome (PNE) is characterised by the presence of neuropathic pain in the pudendal nerve (PN) territory, associated or not with urinary, defecatory and sexual disorders. Surgical PN decompression is an effective and safe alternative for cases when conservative treatment fails. The aim of this study is to describe the first robot-assisted pudendal neurolysis procedure performed in our country. Read More

Actas Urol Esp 2018 Mar 7. Epub 2018 Mar 7.

Unidad de Urología Oncología, UGC Urología-Nefrología, Hospital Universitario Virgen del Rocío, Sevilla, España; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, España.

Objectives: To analyse the learning curve for the management of tyrosine kinase inhibitors as the first line of treatment for patients with metastatic renal cancer.

Material And Methods: We evaluated 32 consecutive patients treated in our department for metastatic renal cancer with tyrosine kinase inhibitors (pazopanib or sunitinib) as first-line treatment between September 2012 and November 2015. We retrospectively analysed this sample. Read More

Actas Urol Esp 2018 Mar 7. Epub 2018 Mar 7.

Servicio de Urología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España. Electronic address:

Actas Urol Esp 2018 Mar 5. Epub 2018 Mar 5.

Servicio de Urología, Hospital General Universitario J.M. Morales Meseguer, Murcia, España.

Actas Urol Esp 2018 Jun 2;42(5):351-352. Epub 2018 Mar 2.

Servicio de Urología, Hospital Vega Baja, Orihuela, Alicante, España.

Actas Urol Esp 2018 Jun 28;42(5):316-322. Epub 2018 Feb 28.

Servicio de Urología, Hospital Universitario de Bellvitge, IDIBELLl, Barcelona, España.

Objectives: To evaluate the effectiveness and safety of simultaneous bilateral percutaneous nephrolithotomy performed in patients affected with bilateral renal calculi.

Materials And Methods: This is a prospective study from September 2012 to November 2016. Patients diagnosed of bilateral kidney stones with abdominal CT scan were included. Read More

Actas Urol Esp 2018 Jun 7;42(5):323-330. Epub 2018 Feb 7.

Health Economics and Outcomes Research, IQVIA, Barcelona, España.

Objectives: To explore the management of lower urinary tract symptoms (LUTS) in men in Spain and assess the compliance with recommendations established in the European Association of Urology (EAU) guidelines.

Material And Methods: MERCURY was an epidemiological and cross-sectional study which involved 227 Urology Units across Spain assessing adult male patients with mixed LUTS and persisting storage symptoms. Sociodemographic, clinical and resource use data for the 6 months prior to study inclusion were collected. Read More

Actas Urol Esp 2018 Jun;42(5):309-315

Servicio de Urología, Hospital General Universitario J. M. Morales Meseguer, Murcia, España.

Background And Objective: Nonmuscle invasive bladder cancer has a high recurrence rate and a low progression rate. The aim of this study was to assess the effectiveness, safety and feasibility of Holmium laser fulguration in an outpatient regimen for selected tumours.

Material And Method: A prospective, longitudinal cohort study was conducted between January 2009 and December 2016. Read More

Actas Urol Esp 2018 Feb 2. Epub 2018 Feb 2.

Unidad de Gestión Clínica de Urología, Hospital Universitario Virgen de las Nieves, Granada, España. Electronic address:

Objectives: This document was developed to establish directives for the follow-up of patients with renal cell carcinoma (RCC) based on the best available scientific evidence and on expert opinions, which can help urologists in the decision-making process and standardise the criteria at the national level.

Material And Methods: The methodology is based on the RAND/UCLA method. A panel of 9 experts on RCC participated in designing a thematic index, identifying and reading the available evidence, formulating recommendations and drafting the content. Read More

Actas Urol Esp 2018 Jun 3;42(5):350-351. Epub 2018 Feb 3.

Centro de Salud Integrado Alto Palancia, Segorbe, Castellón, España.

Actas Urol Esp 2018 Jun 4;42(5):331-337. Epub 2018 Feb 4.

Sección de Urología, Servicio de Cirugía Pediátrica, Hospital Universitario 12 de Octubre, Madrid, España.

Introduction: The short-term results of endoscopic treatment of vesicoureteral reflux (VUR) are excellent. Over time, however, a number of patients have been identified for whom VUR reappeared after being resolved with this technique. The aim of this study was to analyse the factors related to this event. Read More

Actas Urol Esp 2018 May 1;42(4):249-255. Epub 2018 Feb 1.

Department of Urology and Renal Transplantation, Bellvitge University Hospital, IDIBELL, Barcelona, España.

Introduction And Objectives: The management of Prostate cancer (PCa) in renal transplant recipients (RTR) is challenging and remain controversial. Currently there is no consensus about this condition. The aim of the study was to analyse our experience in the diagnosis and management of PCa in RTR. Read More

Actas Urol Esp 2018 Jun 1;42(5):338-343. Epub 2018 Feb 1.

Unidad de Uro-Oncología, Servicio de Urología, Hospital Clínic, Universitat de Barcelona, Barcelona, España.

Objective: To assess the functional effects of prostatic cryosurgery on micturition.

Material And Methods: Prospective study of men who underwent cryosurgery (CS) for prostate cancer between 2013 - 2015. Low urinary tract symptoms (LUTS) and quality of life (QoL) were assessed 1 month before surgery using IPSS questionnaire, a three-day voiding diary (3DVD) and uroflowmetry with ultrasound-measured postvoid residual volume. Read More

Actas Urol Esp 2018 Jan 11. Epub 2018 Jan 11.

Servicio de Urología, Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.

Context And Objective: Bladder reconstruction is performed to replace or expand the bladder. The intestine is used in standard clinical practice for tissue in this procedure. The complications of bladder reconstruction range from those of intestinal resection to those resulting from the continuous contact of urine with tissue not prepared for this contact. Read More

Actas Urol Esp 2018 Jan 10. Epub 2018 Jan 10.

Servicio de Urología, Hospital Universitario de Cabueñes, Gijón, España.

Background: Transrectal ultrasound-guided prostate biopsy (TUPB) is associated with infectious complications (ICs), which are related to a greater prevalence of ciprofloxacin-resistant bacteria (CRB) in rectal flora. We examined the ICs that occurred in 2 groups: A guided antibiotic prophylaxis (GP) group and an empiric prophylaxis (EP) group. We assessed the financial impact of GP. Read More

Actas Urol Esp 2018 May 30;42(4):238-248. Epub 2017 Dec 30.

Servicio de Urología, Hospital Universitario 12 de Octubre, Madrid, España.

Background: The natural progression of bladder tumours (nonmuscle-invasive bladder cancer [NMIBC]) is recurrence with a high rate of progression. Bacille Calmette-Guérin (BCG) has been shown effective in reducing these rates, but there are few comparative studies between strains.

Material And Methods: An observational, prospective and multicentre registry studied 433 patients with a 12-month follow-up visit from 961 registered patients, assessing disease-free survival (DFS), progression-free survival (PFS) cancer-specific survival (CSS) and adverse effects. Read More

Actas Urol Esp 2017 Dec 29. Epub 2017 Dec 29.

Sección de Andrología, Servicio de Urología, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.

Background: Congenital penile curvature is a relatively rare disease, resulting from a deviation of the penis from the body's straight axis when erect. The prevalence is difficult to determine. Although it has been suggested that the condition could affect up to 10% of the male population, most of these deviations are minor, with no clinical or psychological importance, which leads to its underdiagnosis. Read More

Actas Urol Esp 2018 Apr 29;42(3):163-169. Epub 2017 Dec 29.

MRC Centre for Transplantation, King's College London, Londres, Reino Unido; Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, Londres, Reino Unido. Electronic address:

Introduction: Cognitive training is an important training modality which allows the user to rehearse a procedure without physically carrying it out. This has led to recent interests to incorporate cognitive training within surgical education but research is currently limited. The use of cognitive training in surgery is not clear-cut and so this study aimed to determine whether, relative to a control condition, the use of cognitive training improves technical surgical skills on a ureteroscopy simulator, and if so whether one cognitive training method is superior. Read More