Actas Urol Esp (Engl Ed) 2022 04 5;46(3):138-149. Epub 2022 Mar 5.
Xi'an Daxing Hospital, Shaanxi, China; International Doctoral School, University of Seville, Seville, Spain. Electronic address:
Objectives: This meta-analysis has been conducted to evaluate the diagnostic accuracy of circulating microRNAs for the early diagnosis of prostate cancer (PCA).
Methods: A systematic literature search was performed (updated to February 18, 2021) in PubMed, EMBASE, Web of Science, Cochrane Library, Wanfang database and China National Knowledge Infrastructure (CNKI) to identify eligible studies. The pooled sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under curve (AUC) of the summary receiver-operating characteristic (SROC) curve were calculated for both overall and subgroup analysis. Read More