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Actas Urol Esp (Engl Ed) 2022 May 12. Epub 2022 May 12.

Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.

Introduction And Objective: The association of the metabolic syndrome with lithogenesis has been described, especially in uric acid stones. The aim of the work was to analyze the role of the metabolic syndrome in oxalocalcic lithogenesis.

Materials And Methods: Metabolic evaluation of 151 patients including biochemical, hormonal and 24-urine urine parameters, as well as characteristics associated with metabolic syndrome. Read More

Actas Urol Esp (Engl Ed) 2022 May 12. Epub 2022 May 12.

Servicio de Urología, Hospital Universitario Marqués de Valdecilla, Santander, Spain.

Introduction And Objective: Rezūm® system is a minimally invasive transurethral therapy that uses convective water vapor energy to ablate prostatic tissue. The objective is to report 1-year functional and security outcomes obtained by using this technique in real clinical practice.

Material And Methods: Prospective study conducted in 5 Spanish hospitals for the treatment of LUTS secondary to BPH using the Rezūm® system. Read More

Actas Urol Esp (Engl Ed) 2022 May 9. Epub 2022 May 9.

Departamento de Urología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

Introduction: In 2020, 282,421 new cases of cancer were diagnosed in Spain, and urological neoplasms (UN) were among the most frequent ones. Cancer treatment in eldery people is challenging due to fragility and comorbidities of these patients. To meet the needs of treating UN in the eldery, it is necessary to optimize healthcare resources, for which a deep analysis of cancer registries becomes mandatory. Read More

Actas Urol Esp (Engl Ed) 2022 May 9. Epub 2022 May 9.

Department of Urology, Louisiana State University Health Sciences Center, Shreveport, USA. Electronic address:

Objective: Given the challenges involved in diagnosis and treatment of pregnant women with urolithiasis, we aim to review the imaging modalities and current endourological management of these patients.

Materials And Methods: We performed a review of the available literature on urolithiasis in pregnancy. This included evaluation, diagnostic imaging, and therapeutic options. Read More

Actas Urol Esp (Engl Ed) 2022 May 5;46(4):252-258. Epub 2022 May 5.

Servicio de Urología, Hospital General Universitario Gregorio Maranon, Madrid, Spain.

Introduction: Complications arising from ureterovesical anastomosis in kidney transplantation have an important influence on the success of the procedure. The most serious and frequent complications are fistula and stenosis of the ureterovesical junction. The placement of double J stents in anastomosis is currently recommended to reduce these complications. Read More

Actas Urol Esp (Engl Ed) 2022 Apr 28. Epub 2022 Apr 28.

Departamento de Urología, Bakirkoy Hospital de Formación e Investigación Sadi Konuk, Universidad de Ciencias de la Salud, Istanbul, Turkey.

Objective: Although it was stated that supine percutaneous nephrolithotomy (PCNL) was associated with relatively shorter surgical times and comparable success and complication rates, there is no consensus in the current literature concerning the safety and efficacy of supine PCNL in patients with horseshoe kidneys. We aimed to compare supine and prone PCNL regarding safety and efficacy in patients with horseshoe kidneys.

Methods: Data of the patients with horseshoe kidneys who underwent PCNL for renal stones larger than 2 cm between January 2010 and May 2021 were retrospectively reviewed. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 23. Epub 2022 Mar 23.

Departamento de Cirugía y Especialidades Medicoquirúrgicas, Facultad de Medicina y Ciencias de la Salud, Universidad de Oviedo, Oviedo, Spain.

Introduction And Objectives: To evaluate the effect of radical prostatectomy and age on urodynamics before and after intensity-modulated radiation therapy administered to prostate cancer patients.

Materials And Methods: The sample consisted of 40 prostate cancer patients, 22 of whom had undergone a radical prostatectomy. Urodynamic parameters before and after an average of 4. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 22. Epub 2022 Mar 22.

Departamento de Urología, Hospital Santa Chiara, Trento, Italy.

Introduction And Objectives: Our objective is to assess the long-term results of phytotherapy, focusing on the interval between phytotherapy and pharmacological treatment and the predisposing risk factors to such switch on a 10-year follow-up.

Material And Methods: The data of patients taking phytotherapy for mild to moderate male lower urinary tract symptoms (LUTS) from January to December 2010 were retrospectively reviewed from a prospectively maintained database. Patients were followed for 10 years through medical visits and telephone consultations. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 22. Epub 2022 Mar 22.

Department of Urology, CHU d'Angers, Angers, France.

Objective: Off-clamp laparoscopic partial nephrectomy in a hybrid operating room after superselective arterial embolization (hLPN) is a promising minimally invasive approach. In this study, we compared the perioperative surgical outcomes of this innovative technique with the conventional standard of care laparoscopic partial nephrectomy (cLPN) technique.

Patients And Methods: Overall, 86 and 127 patients treated with hLPN and cLPN, respectively, were included. Read More

Actas Urol Esp (Engl Ed) 2022 May 20;46(4):238-244. Epub 2022 Mar 20.

Servicio de Urología, Fundación Instituto Valenciano de Oncología, Valencia, Spain.

Introduction And Objective: Metachronous oligorecurrence in prostate cancer (PCa) occurs in patients with localized disease who, after failed radical treatment, develop oligometastases. Metastasis-directed stereotactic radiotherapy (SBRT) aims to delay androgen deprivation therapy. In this study, we report our experience to elucidate the role of SBRT in a selected population of patients with metachronous oligorecurrence. Read More

Actas Urol Esp (Engl Ed) 2022 May 17;46(4):230-237. Epub 2022 Mar 17.

UGC Urología, Hospital Universitario Puerta del Mar, Cádiz, Spain.

Objectives: To evaluate overall and recurrence-progression rate-adjusted concordance of treatment prescription in non-muscle-invasive bladder cancer (NMIBC) of an app based on the best available scientific evidence and the urologist's opinion.

Methods: Development of an app (APPv) specifically designed for the treatment and follow-up of NMIBC and validation of the proposed APPv treatment endpoint by means of a prospective double-blind observational concordance study of related samples in 100 patients with initial or successive histological diagnosis of NMIBC.

Results: The treatment prescribed by the urologist agrees with that proposed by the APPv in 64% of cases (kappa index 0. Read More

Actas Urol Esp (Engl Ed) 2022 May 16;46(4):193-213. Epub 2022 Mar 16.

Servicio de Urología, Hospital Clinic de Barcelona, Barcelona, Spain.

Introduction And Objective: Survival and quality of life (QoL) of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) deteriorate significantly when they develop metastases. New generation antiandrogens (apalutamide, enzalutamide and darolutamide) can prolong metastasis-free survival (MFS) and overall survival (OS) in these patients, maintaining their QoL.

Material And Methods: After the performance of a systematic review of the literature, a scientific committee reached a consensus on simple and practical recommendations to consolidate and improve the management of patients with nmCRPC in urology consultations. Read More

Actas Urol Esp (Engl Ed) 2022 04 16;46(3):184-192. Epub 2022 Mar 16.

Astellas Pharma S.A., Madrid, Spain.

Introduction And Aim: Overactive bladder (OAB) negatively impacts patient quality of life and may be associated with high resource use. Our aim was to describe the resource use, costs and persistence associated with mirabegron (MB) or antimuscarinic (AM) treatment in patients with OAB.

Materials And Methods: Observational retrospective study of medical records in adult patients initiating OAB treatment with MB or AM in Catalonia. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 8. Epub 2022 Mar 8.

Department of Urology, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.

Objective: To examine clinical practice patterns in locally managing patients under an active surveillance protocol among Portuguese urologists.

Introduction: Prostate cancer (PCa) is a heterogeneous disease with many prostate adenocarcinomas being indolent and a low probability of ever causing symptoms or death. Active surveillance (AS) is a form of conservative management aimed to reduce over-treatment for low-risk PCa patients. Read More

Actas Urol Esp (Engl Ed) 2022 04 8;46(3):178-183. Epub 2022 Mar 8.

Departamento de Urología, Hospital Clínic de Barcelona, Barcelona, Spain.

Introduction: Penile fracture (PF) is a urological emergency with low incidence, and evidence of its long-term outcomes is scarce. This study focuses on postoperative complications and long-term functional outcomes in patients with PF and surgical repair at our center.

Materials And Method: Clinical records of patients undergoing urgent surgery for PF at a third level hospital between 2006 and 2020 were retrospectively reviewed. Read More

Actas Urol Esp (Engl Ed) 2022 04 7;46(3):159-166. Epub 2022 Mar 7.

Servicio de Urología, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Departament de Cirurgia, Universitat Autònoma de Barcelona, Barcelona, Spain.

Introduction: Urinary incontinence after radical prostatectomy (RP) is an adverse event with high impact on patient's quality of life. Nowadays there is no standardized method for urinary continence measurement. Posterior rhabdosphincter reconstruction (PRR) is a surgical step that can improve early urinary continence after RP. Read More

Actas Urol Esp (Engl Ed) 2022 04 7;46(3):150-158. Epub 2022 Mar 7.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Objectives: To describe our initial experience with a new minimally invasive inguinal and pelvic single-access laparoscopic approach, for performing lymph node dissection (LND) in penile cancer: the Pelvic and Inguinal Single Access (PISA) technique.

Material And Methods: 10 patients with different penile squamous cell carcinoma stages (cN0 and ≥pT1G3 or cN1/cN2) were operated by means of the PISA technique, between 2015-2018. Intraoperative frozen section analysis was carried out routinely and if ≥2 inguinal nodes (pN2) or extracapsular nodal extension (pN3) are detected, ipsilateral pelvic LND was performed sequentially as a single-stage procedure and using the same surgical incisions. Read More

Actas Urol Esp (Engl Ed) 2022 May 5;46(4):245-251. Epub 2022 Mar 5.

Departamento de Urología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Program of Adrenal Diseases, CETREN UC, Pontificia Universidad Católica de Chile, Santiago, Chile. Electronic address:

Introduction And Objectives: Laparoscopic surgery is the standard approach for the treatment of adrenal glands. Bilateral synchronous adrenalectomy is rarely performed, and evidence about this procedure is limited. Our objective is to report our 13-year experience with synchronous laparoscopic bilateral adrenalectomy, evaluating its feasibility, safety, and perioperative outcomes. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 5. Epub 2022 Mar 5.

Wake Forest Institute for Regenerative Medicine, Wake Forest University, School of Medicine, North Carolina, USA. Electronic address:

Objective: This study compares the present status and traits of urology residency programs in the United States and China.

Methods: The flow path, structure, curriculum, operative experience, scholarly activities, evaluation systems and other aspects of training were comparatively evaluated between China and the United States.

Results: Urology residency training programs are different between China and the United States in many aspects. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 5. Epub 2022 Mar 5.

Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Introduction: Ureteral access sheath (UAS) is widely used in flexible ureteroscopy and laser lithotripsy (FURS) based on better stone-free rates, lower intrarenal pressure and fewer complications. However, it also rises surgical costs and may injure the ureteral wall. The main objective of our study is to compare safety and efficacy of FURS with and without UAS to evaluate whether its use is justified in all cases. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 5. Epub 2022 Mar 5.

Departamento de Urología, Clínica Universidad de Navarra, Universidad de Navarra, Pamplona, Navarra, Spain.

Objectives: To evaluate the outcomes of robot-assisted radical prostatectomy (RARP) compared to those of open (ORP) and laparoscopic (LRP) surgery. The interest lies fundamentally in the quality-of-life (QoL) evaluation, postoperative recovery, and personal satisfaction of patients with the intervention (PS) beyond oncological and functional outcomes.

Methods: Six hundred eighty-five RPs were performed in our center between 2011-2018 (17,8% ORP, 22,2% LRP and 60% RARP). Read More

Actas Urol Esp (Engl Ed) 2022 Mar 5. Epub 2022 Mar 5.

Department of Urology, Altunizade Hospital, Acibadem M. A. Aydinlar University, Istanbul, Turkey.

Introduction And Objectives: This study aims to investigate the relationship between perineural invasion (PNI) in targeted (TBx) and/or systematic (SBx) prostate needle biopsy and adverse pathological features of prostate cancer (PCa) in prostatectomy specimens.

Materials And Methods: A total of 95 male patients who underwent transperineal TBx and/or concomitant SBx subsequently treated with robot-assisted radical prostatectomy for PCa between October 2015 and June 2020 were included. The performance of PNI as a classification test (sensitivity, specificity, positive and negative predictive values) and its correlation with clinically significant PCa, surgical margin positivity, extraprostatic extension, and seminal vesicle invasion in prostatectomy were computed. Read More

Actas Urol Esp (Engl Ed) 2022 04 5;46(3):138-149. Epub 2022 Mar 5.

Xi'an Daxing Hospital, Shaanxi, China; International Doctoral School, University of Seville, Seville, Spain. Electronic address:

Objectives: This meta-analysis has been conducted to evaluate the diagnostic accuracy of circulating microRNAs for the early diagnosis of prostate cancer (PCA).

Methods: A systematic literature search was performed (updated to February 18, 2021) in PubMed, EMBASE, Web of Science, Cochrane Library, Wanfang database and China National Knowledge Infrastructure (CNKI) to identify eligible studies. The pooled sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under curve (AUC) of the summary receiver-operating characteristic (SROC) curve were calculated for both overall and subgroup analysis. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 5. Epub 2022 Mar 5.

Subdivision of Urethral and Genital Reconstructive Surgery, Urology Department, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires (CABA), Argentina.

Objective: To assess U-score individual values as urethral complex surgery predictors.

Methods: Cross-sectional study including patients who received anterior urethroplasty from 2011 to 2019. U-score (etiology (1-2 points), number of strictures (1-2 points), anatomic location (1-2 points) and length (1-3 points)) was measured individually and globally. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 4. Epub 2022 Mar 4.

Department of Pediatric Urology, Türkiye Health Science University, Bakırköy Research and Teaching Hospital, İstanbul, Turkey.

Aim: We have previously employed the tubularized incised plate (TIP) repair technique in distal hypospadias cases with a few modifications because of its excellent cosmetic results. In this study, we aimed to evaluate the effects of spongioplasty and dorsal dartos flaps, in addition to short urethral stents on the outcomes of TIP repair.

Materials And Methods: Only distal hypospadias cases were involved in this study. Read More

Actas Urol Esp (Engl Ed) 2022 Mar 4. Epub 2022 Mar 4.

Division of Medical Oncology, Department of Internal Medicine, Trakya University School of Medicine, Edirne, Turkey.

Purpose: We designed this study to identify the prognostic value of baseline prognostic nutritional index (PNI) in metastatic castration-resistant prostate cancer (mCRPC) patients treated with abiraterone acetate or enzalutamide.

Methods: 101 mCRPC patients were included. PNI was calculated using formula 10 x serum albumin value (gr/dL) + 0. Read More

Actas Urol Esp (Engl Ed) 2022 04 4;46(3):131-137. Epub 2022 Mar 4.

Servicio de Urología, Hospital Universitario de Basurto, Bilbao, Vizcaya, Spain.

Introduction: Bladder pain syndrome (BPS) is a complex syndrome, without a clearly defined etiology that encompasses different entities, such as interstitial cystitis. This leads to difficulties in establishing a precise definition, obtaining accurate prevalence data, and defining diagnostic criteria and standardized assessment methods. Moreover, there is no consensus regarding the treatment of BPS. Read More

Actas Urol Esp (Engl Ed) 2022 Feb 24. Epub 2022 Feb 24.

Department of Urology, Health Sciences University, Umraniye Training & Research Hospital, Istanbul, Turkey.

Introduction And Objectives: We aim to compare the first year oncological and functional outcomes of Retzius-sparing robot-assisted radical prostatectomy (Rs-RARP) and standard robot-assisted radical prostatectomy (RARP).

Materials And Methods: Eighty-eight patients who underwent robotic radical prostatectomy between 2018-2019 were included. We compared the minimum one-year follow-up results of patients who underwent Rs-RARP or RARP in terms of oncological and functional outcomes. Read More

Actas Urol Esp (Engl Ed) 2022 04 22;46(3):167-177. Epub 2022 Feb 22.

Istanbul Medeniyet University, Faculty of Medicine, Department of Radiology, Istanbul, Turkey.

Objective: Differentiation between renal oncocytoma (RON) and chromophobe renal cell carcinoma (chRCC) remains challenging. We aimed to assess the accurate apparent diffusion coefficient (ADC) radiomics features in differentiating these tumors.

Materials And Methods: This single-center retrospective study included 14 patients with histopathologically proven RON (n = 6) and chRCC (n = 8) who underwent magnetic resonance imaging. Read More

Actas Urol Esp (Engl Ed) 2022 03 22;46(2):63-69. Epub 2022 Feb 22.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Introduction And Objectives: To analyze the evolution of kidney function after laparoscopic partial nephrectomy (PN) and radical nephrectomy (RN) and to identify predictive factors for renal function impairment.

Materials And Method: Retrospective study of patients with two kidneys, glomerular filtration rate (GFR) > 60 mL/min/1.73 m and single renal tumor cT1, treated in our center between 2005 and 2018. Read More