Search Our Scientific Publications & Authors

Actas Urol Esp 2019 Jan 30. Epub 2019 Jan 30.

Escuela de Medicina, Sección de Urología. Universidad del Valle, Cali, Colombia; Grupo de Investigación UROGIV, Universidad del Valle, Cali, Colombia; Profesor Escuela de Medicina, Universidad del Valle, Cali, Colombia. Electronic address:

Objective: To identify scale validation studies for life quality evaluation in patients with bladder cancer.

Methods: Bibliographic search was performed on MEDLINE® via ovid, EMBASE, CENTRAL and LILACS. Subsequently, each of the articles was evaluated, identifying eligibility criteria. Read More

Actas Urol Esp 2019 Jan 28. Epub 2019 Jan 28.

Gallo Uro-Andrology Centre, Nápoles, Italia.

Objectives: To present our experience with multimodal therapy for Peyronie's disease.

Methods: Retrospective data were collected since 2008 to 2017. The following features were evaluated at baseline and after treatment: age, duration of disease, erectile function, erected penile curvature, and stretched penile length. Read More

Actas Urol Esp 2018 Dec 28. Epub 2018 Dec 28.

Department of Urology, Clínica de Urología Avanzada UROZEN, Lima, Perú; Biomedical Research Institute, Universidad Ricardo Palma, Lima, Perú.

Actas Urol Esp 2018 Dec 6. Epub 2018 Dec 6.

Departamento de Urología, Hospital Universitario Ramón y Cajal, Madrid, España.

Context And Objectives: The first-line treatment for >2cm lithiasis is percutaneous nephrolithotomy (PNL), leaving flexible ureteroscopy (fURS) as a second option. In the present review, the stone-free rate and the complications of both techniques were evaluated in the treatment of 2-3cm stones.

Material And Methods: Systematic review of studies that compared both techniques. Read More

Actas Urol Esp 2018 Dec 6;42(10):645-648. Epub 2018 Jul 6.

Servicio de Urología, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, España.

Objective: To recall the history of the discovery of non-nephron cystic disease, detected simultaneously in 2 hospitals in Madrid, and the vicissitudes that the authors endured during the process of recognising this disease, while being ignored by the international scientific literature.

Material And Method: We analysed the authors' first publications and presentations, their correspondence relaying the difficulties in reporting the confusion with adult polycystic kidney disease (APKD) and the subsequent nosological identification of the process. We consulted with individuals who worked with the 2 authors to increase the accuracy and objectivity of the history report. Read More

Actas Urol Esp 2018 Dec 7;42(10):639-644. Epub 2018 Jul 7.

Unidad de Medicina Preventiva, Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España; Centro de Salud Los Cármenes, Madrid, España; Departamento de Medicina Preventiva y Salud Pública, Universidad Rey Juan Carlos, Alcorcón, Madrid, España. Electronic address:

Objective: To assess compliance with the antibiotic prophylaxis protocol for patients who underwent renal surgery and its effect on the incidence of surgical wound infection.

Material And Methods: We performed a prospective cohort study and assessed the overall compliance and each aspect of the antibiotic prophylaxis (start, administration route, antibiotic of choice, duration and dosage) and reported the compliance rates. The qualitative variables were compared with the chi-squared test, and the quantitative variables were compared with Student's t-test. Read More

Actas Urol Esp 2018 Dec 1. Epub 2018 Dec 1.

Departamento de Urología, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela. Electronic address:

Introduction: Benign prostatic hyperplasia is a high prevalence worldwide pathology. Amongst its therapeutic options, there are minimally invasive techniques that use locally injected substances (such as ethanol), which produce a chemoablation of this organ.

Objective: The present work aims to evaluate the efficacy of intraprostatic ethanol injection in the treatment of benign prostatic hyperplasia. Read More

Actas Urol Esp 2018 Nov 20. Epub 2018 Nov 20.

Hospital Universitario Puerta del Mar, Cádiz, España.

Introduction: In recent years urology has been focussing on less invasive forms of laparoscopy with less impact on the abdominal wall. The minilaparoscopy (ML) is promising in this regard. Our objective is to compare the results of a series of patients who underwent minilaparoscopic nephrectomy with another series who underwent conventional laparoscopy (CL). Read More

Actas Urol Esp 2018 Nov 20. Epub 2018 Nov 20.

Hospital Universitari i Politècnic La Fe, Valencia, España.

Introduction And Objectives: Older patients with overactive bladder under antimuscarinic treatment are especially susceptible to cognitive impairment. The aim was to assess short term changes in cognitive function in elderly patients with overactive bladder treated with transdermal oxybutynin.

Materials And Methods: Observational, retrospective, multicentre study in patients with overactive bladder aged 65-80 years undergoing treatment with transdermal oxybutynin. Read More

Actas Urol Esp 2018 Nov 20. Epub 2018 Nov 20.

Servicio de Urología, Hospital Universitario 12 de Octubre, Madrid, España.

Objectives: To evaluate the suitability of empirical antibiotic therapy in HAIs and the antibiotic resistance patterns of the responsible microorganisms, as well as the incidence of mortality and risk factors involved.

Method: A prospective observational study was carried out on patients of both sexes older than 16years, admitted by any urological process during a period of 4years. The incidence and characteristics of HAIs, as well as the causative organism and its resistance, the initial empirical antibiotic therapy and its modification, if required, and mortality rates are analysed. Read More

Actas Urol Esp 2018 Nov 19. Epub 2018 Nov 19.

Servicio de Urología, Hospital de la Vall d'Hebrón, Universidad Autónoma de Barcelona, Barcelona, España.

Context And Objective: There have been significant advances in the knowledge of renal carcinogenesis n the last years. Nowadays, renal tumors are classified according to their genetic profile and specific treatments based on the identification of therapeutic targets have also been developed. However, no prognostic markers have yet been identified. Read More

Actas Urol Esp 2018 Nov 9. Epub 2018 Nov 9.

Departamento de Urología, Hospital Universitari Vall d' Hebron, Universitat Autonoma de Barcelona, Barcelona, España.

Introduction And Aims: Urinary incontinence is a common complication after radical prostatectomy. The aim of our study was to describe the preoperative anatomical features using magnetic resonance imaging in order to predict early continence recovery after robotic radical prostatectomy.

Material And Methods: 72 patients who underwent robotic radical prostatectomy were prospectively analysed. Read More

Actas Urol Esp 2018 Nov 8. Epub 2018 Nov 8.

Servicio de Urología, Hospital Universitario y Politécnico La Fe, Valencia, España.

Objective: Infectious complications (IC) following percutaneous nephrolithotomy surgery (PCNL) can be life-threatening. Our objective was to analyse preoperative predictors of IC in PCNL.

Materials And Methods: A total of 203 patients who underwent PCNL were included in a prospective study between January 2013 and February 2016. Read More

Actas Urol Esp 2018 Oct 22. Epub 2018 Oct 22.

Servicio de Cirugía General y Digestiva, Hospital Universitari Parc Taulí, Universitat Autònoma de Barcelona, Sabadell, Barcelona, España.

Introduction: Given the high prevalence of erectile dysfunction in male population between 40-70 years old and the effect of radical prostatectomy on this domain, it is important to perform a baseline study.

Material And Methods: Prior radical prostatectomy, erectile function has been assessed prospectively in 112 prostate cancer patients using the erectile function (EF) domain of the International Index of Erectile Function (EF-IIEF), Erectile Hardness Score (EHS) and a penile doppler ultrasound (PDUS). Comorbidities and Charlson index were collected. Read More

Actas Urol Esp 2018 Oct 13. Epub 2018 Oct 13.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction And Aim: The main aim of the study was to establish the oncological safety of the laparoscopic approach to radical cystectomy for high-risk, non-organ-confined urothelial tumours.

Material And Methods: A retrospective cohort study of 216 stage pT3-4 cystectomies operated between 2003 and 2016; using an open approach (ORC, n=108), and using a laparoscopic approach (LRC, n=108).

Results: Both groups have similar pathological features except, in G3 TUR, there were more lyphadenectomies and greater pN+, and more adjuvant chemotherapies using the LRC. Read More

Actas Urol Esp 2018 Oct 1. Epub 2018 Oct 1.

Servicio Urologia, Hospital Universitari Son Espases, Palma de Mallorca, España.

Objective: Sarcomatoid urothelial bladder carcinoma comprises 3% of the tumours of the bladder and is considered one of the most aggressive tumours of the urinary tract. Our aim is to analyse the characteristics of sarcomatoid urothelial bladder carcinoma in adults, its treatments and survival.

Method: A retrospective study performed between 2000 and 2017 of all the patients with a sarcomatoid urothelial bladder carcinoma in a single centre. Read More

Actas Urol Esp 2018 Oct 1. Epub 2018 Oct 1.

Hospital Regional de Málaga, Málaga, España.

Introduction: UI after RP is a factor that has a major impact on patients' quality of life and the associated healthcare costs. The definition of UI is very variable in the literature. Similarly, a great many predictors have been studied that affect recovery of continence after surgery, the most important of which are intraoperative. Read More

Actas Urol Esp 2018 Sep 26. Epub 2018 Sep 26.

Unidad de Tumores Renales con Afectación Venosa (TRAV), Servicio de Urología, HGU Gregorio Marañón, Madrid, España.

Introduction And Objective: One of the inherent features of kidney tumours is the capacity to spread inside the venous system as tumour thrombi. The aim of this study was to assess in patients with stage pT3apN0cM0 kidney cancer whether venous tumour involvement influenced tumour recurrence.

Materials And Methods: A retrospective analysis of patients with stage pT3apN0cM0 kidney cancer treated with radical nephrectomy between 1990-2015. Read More

Actas Urol Esp 2018 Sep 24. Epub 2018 Sep 24.

Astellas Pharma SA, Madrid, España.

Introduction And Objectives: Bladder pain syndrome (BPS) is classified as a rare chronic debilitating disease and its diagnosis presents a challenge because its symptoms overlap with those associated with overactive bladder syndrome. The aim of the routine study was to estimate the prevalence of BPS and discover to study the profile of symptoms and clinical practice for patients attending functional urology and urodynamics units.

Material And Methods: An epidemiological study in which 37 functional urology and urodynamics units in Spain participated. Read More

Actas Urol Esp 2018 Sep 20. Epub 2018 Sep 20.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction And Objectives: There is no high-level evidence as to which primary treatment provides an overall survival (OS) or cancer-specific survival (CSS) advantage in high-risk localised prostate cancer (HRLPC). Our aim was to analyse the differences in survival and predictive factors in this group of patients, according to their primary treatment (radical prostatectomy (RP) or radiotherapy and androgen blockade (RT+HT)).

Material And Methods: A retrospective study of 286 HRLPC patients diagnosed between 1996-2008, treated by RP (n=145) or RT+HT(n=141). Read More

Actas Urol Esp 2019 Jan - Feb;43(1):12-17. Epub 2018 Aug 18.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense, Madrid, España.

Introduction: Evaluation of the effectiveness of cognitive biopsy (CB) in patients with clinical suspicion of prostate cancer (PC), and at least one negative biopsy (TRB).

Material And Method: Retrospective study of 144 patients with at least one previous TRB and magnetic resonance imaging (MRI). The MRI nodules were classified based on PI-RADS v2 grouping pZa, pZpl and pZpm as the peripheral zone(PZ), Tza, Tzp and CZ as the transitional zone (TZ), and the AS zones as the anterior zone (AZ). Read More

Actas Urol Esp 2019 Jan - Feb;43(1):18-25. Epub 2018 Aug 14.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction And Objectives: The onset of second primary tumours should be considered in high-risk prostate cancer patients in the natural course of the disease. Our aim was to evaluate the influence of primary treatment with curative intent for these patients on the development of second primary tumours.

Material And Methods: A retrospective study of 286 patients diagnosed between 1996 and 2008, treated by radical prostatectomy (n=145) or radiotherapy and androgen blockade (n=141). Read More

Actas Urol Esp 2019 Jan - Feb;43(1):32-38. Epub 2018 Aug 9.

Servicio de Urología, Hospital Universitario Central de Asturias, Oviedo, España.

Introduction: New imaging studies have appeared in recent years for the diagnosis and follow-up of metastatic urological tumours.

Material And Methods: A total of 41 patients were reviewed with suspected recurrence of a urothelial or kidney tumour, analysing the diagnostic performance of PET-CT scans undertaken between 2013 and 2016.

Results: We collected 17 urothelial tumours and 24 renal tumours, with a median follow-up of 30 months. Read More

Actas Urol Esp 2019 Jan - Feb;43(1):26-31. Epub 2018 Aug 9.

Kulkarni Center for Reconstructive Urology, Pune, India.

Purpose: To evaluate the role and success rate of urethral reconstruction in patients with urethral stricture previously treated with thermos-expandable Memokath™ urethral endoprosthesis.

Materials And Method: A case series of patients with urethral stricture and Memokath™ endoprosthesis treated with urethroplasty is presented. Reconstruction was decided due to stricture progression or complications derived from primary stent treatment. Read More

Actas Urol Esp 2018 Aug 3. Epub 2018 Aug 3.

Servicio de Urología, Hospital Universitario Carlos Haya, Málaga, España.

Introduction: In castration-resistant prostate cancer (CRPC), early detection of metastases is essential for the selection of treatment, and prevention of bone complications. However detecting incipient metastases remains a challenge as the conventional radiological tests (bone scintigraphy or computerised tomography) lack sufficient sensitivity. Diagnostic imaging techniques are currently available that have greater sensitivity and specificity, but are little used due to shortfalls in the recommendations. Read More

Actas Urol Esp 2019 Jan - Feb;43(1):44-50. Epub 2018 Jul 29.

Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, España.

Introduction: The artificial urinary sphincter (AUS) is not used extensively in the treatment of female urinary stress incontinence (USI) due to the poor reproducibility of the techniques used. We describe a new approach to laparascopic implantation, of which dissection of the vesicovaginal space is an essential step. This enables an approach under direct vision to the posterior surface of the bladder neck. Read More

Actas Urol Esp 2018 Dec 2;42(10):616-624. Epub 2018 Jul 2.

Hospital Virgen de las Nieves, Granada, España.

Context: The elimination of bone metastases, restoration and/or preservation of bone morphology and prevention and/or delay of skeletal events are a fundamental objective in the management of metastatic castration-resistant prostate cancer (mCRPC). Radium-223 is the first targeted alpha therapy with effects on bone that has been shown to increase survival in these patients, besides providing other bone-related benefits.

Objective: To analyze the impact of bone metastasis on mCRPC, and the benefits and the window of opportunity provided by radium-223 in the treatment of patients with mCRPC in the current treatment era. Read More

Actas Urol Esp 2019 Jan - Feb;43(1):52-53. Epub 2018 Jul 19.

Departamento de Urología, Complexo Hospitalario Universitario de Ourense, Ourense, España.

Actas Urol Esp 2019 Jan - Feb;43(1):51-52. Epub 2018 Jul 17.

Centro de Salud José María Álvarez, Don Benito, Badajoz, España. Electronic address:

Actas Urol Esp 2019 Jan - Feb;43(1):1-3. Epub 2018 Jul 17.

Departamento de Urología, Complexo Hospitalario Universitario de Ourense, Ourense, España.

Actas Urol Esp 2018 Nov 13;42(9):610. Epub 2018 Jul 13.

Department of Anesthesiology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, EE. UU.. Electronic address:

Actas Urol Esp 2018 Oct 21;42(8):488-498. Epub 2018 Jun 21.

Servicio de Urología, Complejo Hospitalario Universitario de Granada, Granada, España.

Objective: To put forth new findings of urologic oncology with impact on clinical practice presented during 2017 in the main annual meetings.

Methods: This document reviews abstracts on prostate, kidney and bladder cancer presented at the congresses of 2016 (EAU, AUA, ASCO, ESMO and ASTRO) and publications with the highest impact in this period valued with the highest scores by the OncoForum committee.

Results: Among patients at high risk of recurrent renal cell carcinoma after nephrectomy, adjuvant sunitinib compared to placebo showed a benefit in patients at higher risk of recurrence. Read More

Actas Urol Esp 2018 Nov;42(9):567-573

Centro Hospitalar São João, Oporto, Portugal.

Objectives: Feasibility study to evaluate efficacy and safety of Adjustable Transobturator Male System (ATOMS) for male stress urinary incontinence (SUI) after transurethral resection of the prostate.

Materials And Methods: Twenty patients were implanted ATOMS for SUI caused by transurethral resection of the prostate with or without radiotherapy. Incontinence severity was evaluated as mild (2 pads/day), moderate (3-5 pads/day) or severe (≥6pads/day), and dryness as none or one security pad/day. Read More

Actas Urol Esp 2018 Dec 15;42(10):611-613. Epub 2018 Jun 15.

Unidad del Dolor, Hospital Don Benito-Villanueva de la Serena, Don Benito, Badajoz, España.

Actas Urol Esp 2018 Dec 12;42(10):625-631. Epub 2018 Jun 12.

University Medical Centre, Utrecht, The Netherlands.

The standardisation working group of the International Continence Society has updated the Good Urodynamic Practice directives. This evidence-based ICS-GUP2016 has defined the terminology and standards of Urodynamic practice, for the laboratory and for individual practice, in quality control during cystometry and pressure-flow analysis. In addition, the working group included recommendations prior to the test and information about how to prepare the patient, as well as recommendations for the reporting of urodynamics. Read More

Actas Urol Esp 2018 Oct 11;42(8):485-487. Epub 2018 Jun 11.

Unidad de Urología Oncológica, Departamento de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Actas Urol Esp 2018 Dec 10;42(10):614-615. Epub 2018 Jun 10.

Department of Surgery, Oncology and Gastroenterology, Urology, University of Padova, Padua, Italia. Electronic address:

Actas Urol Esp 2019 Jan - Feb;43(1):4-11. Epub 2018 Jun 8.

Grupo Español de Cáncer de Próstata, Madrid, España.

Aims: To describe the 3-year progression-free survival (PFS), overall survival (OS) and disease-specific mortality in the prospective prostate cancer GESCAP cohort, as well as the progression to castration resistance in patients on hormone therapy.

Material And Methods: Prospective, observational, epidemiological, multicentre study. Of the 4087 patients recruited, 3843 were evaluable. Read More

Actas Urol Esp 2019 Jan - Feb;43(1):39-43. Epub 2018 Jun 7.

Departamento de Urología pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction: ureteral stump syndrome is defined as a recurrent urinary infection, low abdominal pain and haematuria in patients with a history of nephrectomy. Its incidence is low and the symptoms are non-specific. The aim of our paper was to present our results with endoscopic treatment of symptomatic ureteral remnants. Read More

Actas Urol Esp 2018 Nov 1;42(9):551-556. Epub 2018 Jun 1.

Unidad Urología Oncológica, Departamento de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Context: Writing skills and the importance of drafting quality are often disregarded. Just as there are guidelines on what each part of a scientific article should comprise (introduction, material and methods, results and conclusion), there are 'norms' as to how to draft the article. Novel results can only be appropriately reflected in a formal and structurally correct text. Read More

Actas Urol Esp 2018 Sep 24;42(7):423-424. Epub 2018 May 24.

Director de Actas Urológicas Españolas. Electronic address:

Actas Urol Esp 2018 Nov 18;42(9):545-550. Epub 2018 May 18.

Servicio de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Context: A correctly drafted original article gives information on what was done, why it was done, how it was done, the result of what was done, and the significance of what was done. Many articles fail to report their results effectively.

Objective: To describe the characteristics of an original article and to give practical recommendations to prevent the most common errors in our environment. Read More

Actas Urol Esp 2018 Dec;42(10):659-662

Departamento de Urología, Complexo Hospitalario Universitario de Ourense, Ourense, España.

Actas Urol Esp 2018 Oct;42(8):483-484

Grupo Español para el Tratamiento del Cáncer Renal (GECARE).

Actas Urol Esp 2018 Nov;42(9):586-592

Oficina de Historia de la Asociación Española de Urología, Madrid, España. Electronic address:

Introduction And Objectives: We researched the start of urological specialisation in Spain, from the end of the 19th century to the institution of the education system (resident medical intern) to learn about the centres and individuals who created the urological teaching units and training schools in which the first Spanish urologists specialised their training.

Material And Methods: We extracted the references from books on the history of urology, from periodic urological publications and from the posters on history submitted to the congresses of the Spanish Urological Association and filled in the data and dates with the Historical Dictionary of Spanish Urologists.

Result: There are 30 urological specialization centres, 8 with official accreditation recognised by the corresponding ministry but whose official status is unknown. Read More

Actas Urol Esp 2018 Oct 3;42(8):499-506. Epub 2018 May 3.

Hospital Clínic, Barcelona, España; EAU Guidelines Office Board Member.

Context: The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the top of the levels-of-evidence pyramid.

Acquisition Of Evidence: The review process should be well developed and planned to reduce biases and eliminate irrelevant and low-quality studies. Read More

Actas Urol Esp 2018 Dec 23;42(10):632-638. Epub 2018 Apr 23.

Departamento de Urología, Universidad Estatal de Campinas (UNICAMP), São Paulo, Brasil.

Objectives: To explore the proportion of patients with higher risk localized prostate cancer (PCa) that would become safely biopsy negative 12 months after non-thermal focal therapy with padeliporfin vascular-targeted photodynamic therapy (VTP).

Methods: Multicenter study in a scenario of prostate-specific antigen (PSA) ≤20ng/ml and variable PCa target volumes Gleason pattern 3 or low-volume secondary Gleason pattern 4, all patients received VTP, consisting of intravenous 4mg/kg padeliporfin activated by light-diffusing fibers in the prostate. The prostate was biopsied at baseline, months 6 and 12, PSA, patient-reported functional outcomes and quality of life (QoL) questionnaires were recorded at baseline, months 3, 6, and 12 and adverse events (AE) throughout the study. Read More

Actas Urol Esp 2018 Oct 24;42(8):538-541. Epub 2018 Apr 24.

Servicio de Urología, Hospital Universitario Donostia, Donostia-San Sebastián, Guipúzcoa, España.

Background: Renal cell carcinoma has a natural tendency to extend through the renal vein. When the thrombus reaches the vena cava, thrombectomy and the necessary reconstruction of the vena cava are typically performed by open pathway. Robot-assisted technology provides advantages for performing this complex technique, using a minimally invasive access. Read More

Actas Urol Esp 2018 Apr 20. Epub 2018 Apr 20.

Hospital Universitario Dr. Peset, Valencia, España.

Background: The intravesical administration of hazardous drug products is a standard practice in the urology setting, which potentially exposing medical personnel to these drug products. It was deemed necessary to have a consensus document among the scientific societies involved (the Spanish Urological Association and the Spanish Society of Hospital Pharmacy) that collects the best available evidence on the safest handling possible of dangerous drug products in the setting of urology departments.

Methods: We reviewed the legislation and recommendations on the handling of dangerous drug products, both at the national and international level. Read More

Actas Urol Esp 2018 Nov 17;42(9):606-609. Epub 2018 Apr 17.

Unidad de Litiasis, Servicio de Urología, Fundacio Puigvert, Barcelona, España.

Introduction: There are currently 3holmium laser, YAG (Ho:YAG) endolithotripsy procedures that are considered basic (fragmentation, pulverisation, "pop-corn" technique). We present the technique of fragmentation targeted at preferred discontinuities (FTPD), a new concept of endolithotripsy by Ho:YAG laser.

Material And Methods: The FTPD technique is based on the selective application of energy (targeting a specific preselected point) to an area that is visually prone to the formation of a fracture line or preferred discontinuity (conditioned by the anisotropy of the urolithiasis). Read More