851 results match your criteria Acta reumatologica portuguesa[Journal]


Obesity, metabolic syndrome and other comorbidities in rheumatoid arthritis and psoriatic arthritis: influence on disease activity and quality of life.

Acta Reumatol Port 2019 Oct-Dec;44(4):322-324

Rheumatology department, Unidade Local de Saúde do Alto Minho, Ponte de Lima.

In obesity, especially if visceral, and in rheumatic diseases, the production of pro-inflammatory cytokines contributes to an increased cardiovascular risk. Moreover, classic cardiovascular risk factors are more common in these patients. We intended to assess the influence of body mass index (BMI), abdominal circumference (AC) and metabolic syndrome (MS) on disease activity and quality of life in Rheumatoid Arthritis (RA) and Psoriatic Arthritis patients and to compare the results between the RA and PsA patients. Read More

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Loss to follow-up in registries of rheumatic patients treated with biologics: a potential information bias in assessing pharmacovigilance and efficacy outcomes.

Acta Reumatol Port 2019 Oct-Dec;44(4):281-287

Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal; Unidade de Investigação em Reumatologia, IMM, Faculdade de Medicina, Universidade de Lisboa.

Background: The information associated with loss to follow-up (LFU) patients may affect real-world data evaluation of the use of biologics that is not being adequately captured in registries.

Methods: We identified all patients (Pts) treated with biologics in our center who had no visits registered for more than 6 months, in the Rheumatic Diseases Portuguese Register, Reuma.pt. Read More

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Intensity of inflammation as the most important predictor of myocardial involvement in JIA. A 3D echocardiographic study.

Acta Reumatol Port 2019 Oct-Dec;44(4):296-302

Faculty of Medicine/Cairo University.

Introduction: Myocardial dysfunction is an important complication in the context of juvenile idiopathic arthritis (JIA). Several mechanisms might be involved in the induction of myocardial injury in such a disabling disease. Among several factors involved, myocardial inflammation and cardiotoxic drugs were thought to be the most incriminated factors. Read More

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Benign transient hyperphosphatasemia in Juvenile Idiopathic Arthritis: a case report.

Acta Reumatol Port 2019 Oct-Dec;44(4):317-319

Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa.

Benign transient hyperphosphatasemia of infancy and early childhood is a self-limiting condition characterized by transiently increased serum alkaline phosphatase in the absence of liver, kidney or metabolic bone diseases. It is often accidentally found in children under five years old and it might be associated with a variety of underlying clinical disorders. Its pathophysiology remains unclear. Read More

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Balance and falls in axial Spondyloarthritis: a cross sectional study.

Acta Reumatol Port 2019 Oct-Dec;44(4):248-253

Mackenzie Evangelical Hospital, Curitiba, PR, Brazil.

Background: Spondyloarthritis (SpA) patients may suffer from balance loss predisposing them to falls.

Aim: To study balance impairment and falls in axial SpA patients and its association with clinical and epidemiological variables, disease activity, functional and metrology indexes.

Methods: Cross-sectional study of 55 SpA patients with axial disease. Read More

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Hand function and adaptive equipment use in patients with rheumatoid arthritis.

Acta Reumatol Port 2019 Oct-Dec;44(4):273-280

Centro de Reabilitação do Norte.

Objectives: Evaluation and characterization of hand function in patients with rheumatoid (RA) arthritis and, secondarily, identification of the use of adaptive equipments.

Material And Methods: Firstly, a written informed consent was obtained and then an anonymous questionnaire was filled by RA outpatients after observation at the rheumatology consultation with no other musculoskeletal or neuromuscular disorders that would determine major functional impairment of hand function. Sociodemographic and clinical variables were collected and the Cochin Hand Functional Scale (CHFS) was applied. Read More

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Innovation and digital transformation to support clinical care and prevent osteoporosis related fractures

Acta Reumatol Port 2019 11 1;44(3):171-172. Epub 2019 Nov 1.

EpiDoC Unit, CEDOC, NOVA Medical School, UNL

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November 2019

How challenging can neuropsychiatric systemic lupus erythematous be? experience from a tertiary care centre.

Acta Reumatol Port 2019 Oct-Dec;44(4):312-316

Hospital Garcia de Orta.

Neuropsychiatric Systemic Lupus Erythematous comprises several neurologic and psychiatric manifestations attributable to Lupus Erythematous Systemic. Diagnosis implies exclusion of non- Systemic Lupus Erythematous -related diseases that might mimic the same symptoms and should be prompt in order to avoid delaying the treatment. Treatment is dictated by the underlying pathogenesis and includes immunosuppression and/or anti-platelet agents/anticoagulation. Read More

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February 2020

Transition in a paediatric rheumatology unit - experience from a tertiary unit.

Acta Reumatol Port 2019 Oct-Dec;44(4):320-321

Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Unidade de Investigação em Reumatologia, IMM, Faculdade de Medicina da Universidade Lisboa.

The transition from paediatric to adult health care has been recognised as a priority in recent years. Health care transition (HCT) is defined as the process of moving from a paediatric to an adult model of health care with or without a transfer of follow up to a different clinician. In our centre, the transition begins around 11 years, when the patient education process starts and at the same time enable adolescents and young adults (AYA) to acquire knowledge to manage their disease. Read More

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February 2020

Biologic therapy use and pregnancy outcomes in women with immune-mediated inflammatory rheumatic diseases.

Acta Reumatol Port 2019 Oct-Dec;44(4):266-272

Hospital Garcia da Orta.

Introduction: Concerns about the side effects and interactions of biologic drugs with reproduction and pregnancy have been always an issue between experts. The safety of these therapies during conception and/or pregnancy is not fully understood. The aim of this study was to assess the exposure to biologic drugs before and/or during conception/pregnancy and the risk of adverse pregnancy outcomes in women with rheumatic diseases. Read More

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February 2020

Psoriatic arthritis and ankylosing spondylitis impact on health-related quality of life and working life: a comparative population-based study.

Acta Reumatol Port 2019 Oct-Dec;44(4):254-265

EpiReumaPt Study Group - Sociedade Portuguesa de Reumatologia; Centro de Estudo de Doenças Crónicas (CEDOC), EpiDoc Unit, NOVA Medical School, Universidade Nova de Lisboa (NMS/UNL).

Introduction: Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are chronic disorders that significantly impact patients' quality of life (QoL), health care systems and society. There is very little data on the epidemiology and the impact of PsA and AS in Portugal, so in this study we aim to: 1) estimate the prevalence of PsA and AS in the adult Portuguese population; 2) compare health-related quality of life (QoL) of PsA and AS with the one of other rheumatic and musculoskeletal diseases (RMD) and with subjects with no rheumatic diseases; 3) compare early retirement and productivity loss among PsA and AS with other RMD.

Methods: We used data from EpiReumaPt, a population-based survey, conducted from 2011 to 2013, in which 10661 subjects over 18 years old were screened for RMD. Read More

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February 2020

Efficacy, immunogenicity and cost analysis of a systematic switch from originator infliximab to biosimilar CT-P13 of all patients with inflammatory arthritis from a single center.

Acta Reumatol Port 2019 Oct-Dec;44(4):303-311

Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.

Biosimilar drugs are intended to be as effective as the originator product but with a lower cost to healthcare systems. In our center we promoted a switch from originator infliximab (IFXor) to biosimilar infliximab (CT-P13). We analyzed efficacy, safety, immunogenicity and cost savings of switching. Read More

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November 2019
5 Reads

Fall determinants in the adult Portuguese: do chronic conditions change the risk of falling?

Acta Reumatol Port 2019 Oct-Dec;44(4):288-295

Departamento de Medicina e CINTESIS, Faculdade de Medicina da Universidade do Porto (FMUP).

Objectives: Falls are a major public health issue, given its prevalence and social impact. This study aimed to (1) characterize fallers in the adult Portuguese population as well as (2) identify if some chronic conditions are fall determinants.

Material And Methods: Our data of 7403 adults (≥18 years) was retrieved from phase 1 survey of EpiReumaPt, a representative sample of adult Portuguese population. Read More

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November 2019

Tongue ischemia - an unusual presentation of Giant Cell Arteritis.

Acta Reumatol Port 2019 Jul-Sep;44(3):273-275. Epub 2019 Sep 29.

Hospital Divino Espírito Santo de Ponta Delgada, EPE.

Unusual presentations of Giant Cell Arteritis (GCA) can sometimes delay the diagnosis and its prompt treatment. An 83-year-old male patient was admitted in the emergency department with a few hours evolution of tongue swelling, dysphagia and dysarthria. He also complained of a bitemporal headache with about 4 months of evolution and resistant to all treatment prescribed, including ergotamine, that he had started one week before. Read More

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September 2019
1 Read

Endothelin-1 serum levels in women with Rheumatoid Arthritis.

Acta Reumatol Port 2019 Jul-Sep;44(3):250-257. Epub 2019 Sep 24.

Hospital Universitario San Cecilio, Granada, Spain.

Objective: The purpose of this study was to evaluate serum Endothelin-1(ET-1) levels in women Rheumatoid Arthritis (RA) patients compared with healthy controls, examine possible associations between ET-1 with different characteristic of the disease and investigate possible associations between ET-1 with surrogate markers of cardiovascular disease (CVD).

Methods: This cross-sectional study was performed in Vega-Baja Hospital, Orihuela (Spain) from November 2016 to May 2018. Sixty-three women with RA and sixty-five age and sex healthy controls were included in this study. Read More

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September 2019
1 Read
0.831 Impact Factor

First steps to understand productivity loss in Portuguese patients with rheumatoid arthritis.

Acta Reumatol Port 2019 Jul-Sep;44(3):282-283. Epub 2019 Sep 24.

Centro Hospitalar de Vila Nova de Gaia/Espinho.

Rheumatoid Arthritis (RA), in consequence of joint inflammation and damage, is known to lead to productivity loss. Developments during the 21st century, such as biologic treatments, allowed remission/low disease activity to be achieved in more RA patients. Despite this, evidence is equivocal concerning work outcomes improvement. Read More

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September 2019
1 Read

Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia.

Acta Reumatol Port 2019 Jul-Sep;44(3):244-249. Epub 2019 Sep 29.

Universidad de Sevilla.

Objective: The objective of this study is to evaluate the effectiveness of autohemotherapy with ozone in the management of fibromyalgia (FM).

Design: 20 FM patients (according to the criteria of the American College of Rheumatology), were treated with 10 sessions of ozone hemotherapy (2 sessions per week) with a concentration of 30-60 mcgr/ml. The health condition of the patients was evaluated before and after treatment, through the Fibromyalgia Impact Questionnaire (FIQ). Read More

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September 2019
2 Reads

Bilateral vertebral artery occlusion without stroke secondary to giant cell arteritis.

Acta Reumatol Port 2019 09 23;44(3):270-272. Epub 2019 Sep 23.

University of Medicine and Pharmacy Targu Mures.

Ultrasound examination has become an important tool in the diagnosis of giant cell arteritis, revealing the suggestive hypoechoic arterial wall thickening (halo sign). Vertebral artery involvement is not unusual in giant cell arteritis, but bilateral vertebral artery occlusion secondary to this affection is a rare condition and only a few cases have been reported so far. We report a case of an 84-year-old male patient with anterior ischaemic optic neuropathy secondary to giant cell arteritis, with bilateral occlusion of the vertebral arteries manifested with nonspecific neurological signs, detected during the ultrasound scan of the cervical arteries. Read More

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September 2019
2 Reads

Rheuma SPACE - Standard Practice Aiming Clinical Excellence: description of the methodological approach.

Acta Reumatol Port 2019 Sep 8. Epub 2019 Sep 8.

Rheuma SPACE study group.

Background: Quality of care is a key component of the right to health, and the route to equity and dignity. The aim of the project Rheuma SPACE - Standard Practice Aiming Clinical Excellence was to develop a set of quality indicators focused in rheumatoid arthritis care and apply them to rheumatology departments of the Portuguese National Health Service in order to benchmark the care for these patients. This article details the methodology that was applied. Read More

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September 2019

Pleuroparenchymal Fibroelastosis in association with Connective Tissue Disease: a new interstitial pneumonia to be aware of.

Acta Reumatol Port 2019 Aug 7. Epub 2019 Aug 7.

Centro Hospitalar Universitário de São João, Porto, Portugal.

Pleuroparenchymal fibroelastosis (PPFE) is a rare and recently described interstitial pneumonia. It consists of progressive fibrosis involving the pleura and subpleural lung parenchyma, predominantly in the upper lobes, with defined and reproducible clinical, radiological and histopathological criteria. No effective treatment has yet been shown to modify the natural course of the disease, which vary greatly in the literature. Read More

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Granulomatosis with polyangiitis with isolated orbital involvement in children: a case report successfully treated with Rituximab and review of literature.

Acta Reumatol Port 2019 07 8;44(Jul-Sep (3)):258-263. Epub 2019 Jul 8.

We report the case of a 15-year old girl who presented with a non-tender right upper eyelid swelling. Magnetic resonance confirmed the presence of an enlargement of the orbicular muscle with moderate contrast enhancement. Biopsy revealed the presence of necrotizing granulomatous vasculitis. Read More

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July 2019
10 Reads

Chondrosarcoma as inaugural manifestation of monostotic Paget's disease of Bone.

Acta Reumatol Port 2019 Apr-Jun;44(2):163-164

Centro Hospitalar São João.

Sarcomatous degeneration is one of the serious and rare complications of Paget's disease of bone. Osteosarcoma is the most common secondary tumour, while other variants such as chondrosarcoma are extremely uncommon. We describe a unique case of Paget's chondrosarcoma of the pelvis in an elderly female patient, with no previous established diagnosis of osteitis deformans. Read More

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February 2020
2 Reads

Tumoral calcinosis in a rheumatoid arthritis patient - a rare case report.

Acta Reumatol Port 2019 Apr-Jun;44(2):158-160

Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Portugal.

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February 2020

The geyser sign: an unusual presentation of a rotator cuff tear.

Acta Reumatol Port 2019 Apr-Jun;44(2):155-157

Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Portugal.

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February 2020

Tocilizumab in refractory juvenile idiopathic arthritis with associated uveitis: a case report.

Acta Reumatol Port 2019 Apr-Jun;44(2):151-154

Centro Hospitalar Vila Nova de Gaia/Espinho.

Introduction: We report a 9-year follow-up of a child with refractory juvenile idiopathic arthritis (JIA) with associated uveitis in which tocilizumab proved to be effective in achieving disease control.

Case Report: A 16-month child was diagnosed with JIA and at the age of 3 developed bilateral non-granulomatous anterior uveitis. Throughout the follow-up, the patient presented frequent joint and ocular flares. Read More

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February 2020
4 Reads
0.831 Impact Factor

Non-Pharmacological and Non-Surgical Interventions for Knee Osteoarthritis: A Systematic Review and Meta-Analysis.

Acta Reumatol Port 2019 07 29;44(3):173-217. Epub 2019 Jul 29.

Polytechnic Institute of Coimbra.

Objective: The aim of the present systematic review and meta-analysis is to know, based on the available randomized controlled trials, if the non-surgical and non-pharmacological interventions commonly used for knee osteoarthritis (OA) patients are effective and which are the most effective ones.

Material And Methods: RCTs were identified through electronic databases respecting the following terms to guide the search strategy: PICO (Patients - Humans with knee OA; Intervention - Non-surgical and non-pharmacological interventions; Comparison - Pharmacological, surgical, placebo, no intervention, or other non-pharmacological/non-surgical interventions; Outcomes - Pain, physical function and patient global assessment). The methodological quality of the selected publications was evaluated using the PEDro and GRADE scales. Read More

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July 2019
1 Read

Outcomes of rheumatic patients referred from Portuguese speaking African countries for medical evaluation in Portugal.

Acta Reumatol Port 2019 Jul 22. Epub 2019 Jul 22.

Hospital de Santa Maria, Centro Hospitalar Universitário de Lisboa Norte.

Bureaucratic, social and economic barriers may influence several clinical aspects of rheumatic diseases in patients from Portuguese speaking African countries (PALOP) displaced for medical care in Portugal. Despite the apparent advantages of dislocating patients to a more resourceful country, these patients present with long-lasting and severe rheumatic diseases with chronic damage, due to lack of precise diagnosis, ineffective referrals, lack of appropriate treatment and concomitant infectious comorbidities that may jeopardize the outcomes of these strategies. Read More

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Assessment of the vaccination status in rheumatic disease patients treated with disease-modifying antirheumatic drugs.

Acta Reumatol Port 2019 Jul 11. Epub 2019 Jul 11.

Centro Hospitalar e Universitário de Coimbra.

Patients with rheumatic diseases are at a higher risk for infections associated to the underlying pathology and immunosuppressive therapy. This fact leads to an increased morbidity and/or mortality. Effective vaccination is essential for the prevention of a significant number of these infections, namely influenza and pneumococcal vaccination. Read More

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July 2019
3 Reads

Hepatic vasculitis mimicking multiple liver abscesses in Cogan's Syndrome.

Acta Reumatol Port 2019 Jul 8. Epub 2019 Jul 8.

Centro Hospitalar E Universitário De Coimbra, E.P.E.

Cogan's syndrome is a rare inflammatory disorder, classically characterized by interstitial keratitis and sensorineural hearing loss. Inner ear disease may result in deafness. In some patients, it may also be accompanied by systemic vasculitis. Read More

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July 2019
15 Reads

The very early inflammatory triquetral lesion by MRI - is this the first sign in Rheumatoid Arthritis?

Acta Reumatol Port 2019 12 15;44(3):218-224. Epub 2019 Dec 15.

Universidad Autonoma de Nuevo Leon, Facultad de Medicina.

Introduction/aim: Rheumatoid Arthritis (RA) an autoimmune, chronic, and disabling disease if untreated, affects wrist joints, with a diagnostic delay of up to 2 years. Triquetral bone allows rotational movement that pivots over the rest wrist bones, and maintains physiological loads during mobility. Magnetic Resonance Imaging (MRI) is the most sensitive (96%) method for diagnosis, evidencing lesions as early as in the initial RA stages. Read More

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December 2019
0.831 Impact Factor

Dermatoscopic and Mucoscopic Features of Lesions in Patients with Behcet's Disease.

Acta Reumatol Port 2019 12 15;44(3):225-231. Epub 2019 Dec 15.

Objective: Behcet's disease (BD), as a vasculitis, can affect small and large vessels. As dermatoscopy has been shown to improve the accuracy in diagnosis of various skin lesions especially vascular patterns, we set this study to find if there is any characteristic pattern in the dermatoscopy of Behcet's mucocutaneous lesions.

Methods: This prospective cross-sectional observational study designed to evaluate dermatoscopic features of Behcet's mucocutaneous lesions. Read More

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December 2019
13 Reads
0.831 Impact Factor

How to diagnose lupus enteritis early? Lessons learned from a multicenter case series.

Acta Reumatol Port 2019 Apr-Jun;44(2):145-150

Centro Hospitalar e Universitário de Coimbra.

Introduction: Lupus enteritis (LE) is a rare, potentially life-threatening manifestation of systemic lupus erythematosus (SLE). Early diagnosis is crucial for early treatment and prevention of serious complications such as ischemic enteritis, bowel infarction with bleeding and/or perforation and peritonitis. The objective of this case review is to identify strategies for early diagnosis of LE. Read More

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February 2020
13 Reads

Antifibrotics in interstitial lung disease related to connective tissue diseases - a paradigm shift in treatment and outcome.

Acta Reumatol Port 2019 Apr-Jun;44(2):161-162

Hospital Garcia de Orta.

Interstitial lung disease (ILD) is one of the major causes of morbidity and mortality in patients with connective tissue disease (CTD) and the treatments available until nowadays are in most cases unable to halt disease progression. CTD-ILD pathogenesis includes an initial inflammatory phase, followed by a fibrotic phase, in which extracellular matrix proteins are produced and fibrotic scaring tissue within the lung develops. Steroids and immunosuppressants are the weapons we currently have to treat CTD-ILD. Read More

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February 2020
2 Reads

The relationship between anthropometric status and rheumatoid arthritis. Exploring the role of nesfatin and asymmetric dimethylarginine.

Acta Reumatol Port 2019 Apr-Jun;44(2):126-131

Objective: The aim of this study was to explore the anthropometric status of rheumatoid arthritis (RA) patients, as well as two controversial adipokines, namely nesfatin-1 and asymmetric dimethylarginine (ADMA), to reveal the possible relationships between them and RA.

Methods: This study included RA patients who fulfilled the American college of rheumatology classification criteria. Anthropometric parameters including height, weight, and waist circumference (WC) were measured and body mass index (BMI) was calculated. Read More

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February 2020
2 Reads

Low persistence with oral biphosphonate treatment in postmenopausal osteoporosis.

Acta Reumatol Port 2019 Apr-Jun;44(2):114-125

CEDOC, Faculdade de Ciências Médicas, Universidade Nova de Lisboa & Serviço de Reumatologia, CHLO,EPE / Hospital Egas Moniz, Lisboa, Portugal.

Background: Osteoporotic fractures are a major cause of morbidity and mortality. It is recognized that persistence with medication is crucial to reach optimal clinical outcomes. We aimed to estimate the persistence level to weekly and monthly oral bisphosphonates (OBP) in women with postmenopausal osteoporosis (PMO) over 24 months from therapy initiation in a population-based setting. Read More

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February 2020
2 Reads

Intravenous human immunoglobulin for the treatment of recurrent focal myositis.

Acta Reumatol Port 2019 Jan-Mar;44(1):88-89

Hospital Conde de Bertiandos - Unidade Local de Saúde do Alto Minho, Ponte de Lima, Portugal.

We present a case of recurrent focal myositis treated with intravenous human immunoglobulin, after ineffectiveness of analgesics, non-steroidal anti-inflammatory drugs, corticosteroids and immunosuppressive therapies. There was a prompt clinical and laboratorial improvement. To the best of our knowledge, this is the first case reporting the administration of this treatment in recurrent focal myositis. Read More

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January 2020
7 Reads

Dystrophic Calcinosis: Do We Really Know How to Treat It?

Acta Reumatol Port 2019 Jan-Mar;44(1):86-87

Universidade Federal do Amazonas.

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January 2020
2 Reads

POEMS Syndrome: a puzzling case.

Acta Reumatol Port 2019 Jan-Mar;44(1):84-85

CEDOC, NOVA Medical School | Faculdade de Ciências Médicas - NOVA University of Lisbon, Lisbon, Portugal; Hospital de Egas Moniz, CHLO, Lisbon, Portugal.

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January 2020
7 Reads

Osteopoikilosis: case series from Portuguese Rheumatology Centers.

Acta Reumatol Port 2019 Jan-Mar;44(1):78-83

Instituto Português de Reumatologia.

Osteopoikilosis (OPK) is a rare, hereditary, usually asymptomatic disease characterized by the presence of multiple, well-defined sclerotic lesions distributed in peri-articular locations, frequently diagnosed as an incidental finding. Differential diagnosis with osteoblastic metastases is fundamental. This article reports six cases of OPK diagnosed in Portuguese Rheumatology Centers. Read More

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January 2020
3 Reads

Risk of Cardiovascular Involvement in Patients with Primary Sjögren's Syndrome: a large-scale cross-sectional cohort study.

Acta Reumatol Port 2019 Jan-Mar;44(1):71-77

The First Affiliated Hospital of Soochow University, Suzhou.

Objective: To evaluate the presence of cardiovascular involvement and analyze potential risk factors independently associated with cardiovascular involvement in primary Sjögren's syndrome (PSS) patients.

Methods: We recruited a cohort of 367 PSS patients and 367 age- and gender-matched controls from the First Affiliated Hospital of Wenzhou Medical University. Demographic, clinical and laboratory data, and overt cardiovascular involvement events were recorded. Read More

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January 2020
3 Reads

Validation of Rheumatoid Arthritis Quality of Life (RAQoL) Questionnaire into Portuguese Language.

Acta Reumatol Port 2019 Jan-Mar;44(1):65-70

Centro Hospitalar Universitário de Coimbra; Coimbra Institute for Clinical and Biomedical Research (iCBR) - Faculty of Medicine, University of Coimbra, Portugal.

Background: Rheumatoid Arthritis (RA) is a chronic inflammatory disease with high impact on patients´ quality of life (QoL). The Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL) is a self-completed questionnaire designed to assess QoL in patients with RA. A Portuguese adaptation of the RAQoL was available but required formal validation. Read More

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January 2020
3 Reads

Predictors and causes of first-line biologic agent discontinuation in rheumatoid arthritis: data from Reuma.pt.

Acta Reumatol Port 2019 Jan-Mar;44(1):57-64

Hospital Garcia de Orta.

Objectives: To assess the discontinuation of first-line biological treatment and to evaluate the reasons and predictors thereof in patients with rheumatoid arthritis (RA) from daily clinical practice.

Methods: RA patients registered in the Rheumatic Diseases Portuguese Register (Reuma.pt) starting treatment with biologic DMARDs (bDMARDs) were included in this prospective observational study. Read More

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January 2020
4 Reads

Are We Overcalling Sacroillitis on MRI? Differential diagnosis that every rheumatologist should know - Part II.

Acta Reumatol Port 2019 Jan-Mar;44(1):42-56

Musculoskeletal Imaging Unit, Radiology Department, Hospital da Luz, Grupo Luz Saúde, Lisbon, Portugal; Department of Radiology, Hospital Beatriz Ângelo, Loures, Portugal; Department of Radiology, Madeira Medical Center, Hospital Particular da Madeira.

In the second part of this review article we will describe the imaging features of non- spondyloarthritis (SpA) pathologies that may mimic sacroiliitis on Magnetic Resonance Imaging (MRI), and that readers should be aware (part 2). Based on the established literature, there is currently an "overcall" of sacroiliitis on MRIs. In this setting, differential diagnoses and their imaging features come into play. Read More

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January 2020
2 Reads

Are we overcalling sacroiliitis on MRI? Differential diagnosis that every rheumatologist should know - Part I.

Acta Reumatol Port 2019 Jan-Mar;44(1):29-41

Musculoskeletal Imaging Unit, Radiology Department, Hospital da Luz, Grupo Luz Saúde, Lisbon, Portugal; Department of Radiology, Hospital Beatriz Ângelo, Loures, Portugal; Department of Radiology, Madeira Medical Center - Hospital Particular da Madeir.

Diagnosing early spondyloarthritis remains a challenge in routine practice, especially in its axial (SpA) form. Magnetic resonance imaging (MRI) is capable of detecting early bone marrow edema (BME) in the sacroiliac joints (SIJs), a key criterion for the diagnosis of active SpA according to the "imaging arm" of the Assessment of Spondyloarthritis International Society (ASAS) classification. However, despite MRI having superior reliability compared to radiographs and being recognized as a crucial imaging biomarker of SpA, it has several limitations, including its limited specificity and sensitivity. Read More

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January 2020
1 Read

Portuguese recommendations for the use of ultrasound in rheumatology.

Acta Reumatol Port 2019 Jan-Mar;44(1):7-28

Hospital do Divino Espírito Santo, Ponta Delgada, Portugal.

Introduction: Ultrasound (US) is a relatively cheap, easily available and reliable method to improve the care of rheumatic patients. However, its use in rheumatology practice is very heterogeneous and needs to be standardized.

Objectives: To develop recommendations for the use of US in rheumatic diseases endorsed by the Portuguese Society of Rheumatology. Read More

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January 2020
12 Reads

Imaging innovation and rheumatology.

Authors:
Pedro Alves

Acta Reumatol Port 2019 Jan-Mar;44(1):5-6

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January 2020
1 Read

Tocilizumab and rituximab have similar effectiveness and are both superior to a second tumour necrosis factor inhibitor in rheumatoid arthritis patients who discontinued a first TNF inhibitor.

Acta Reumatol Port 2019 Apr-Jun;44(2):103-113

Hospital Garcia de Orta, Almada.

Objectives: To compare the effectiveness of a 2nd TNF inhibitor (TNFi), Tocilizumab (TCZ) and Rituximab (RTX), measured by drug retention and by response rates, in RA patients after discontinuing a first-line TNFi and to clarify the reasons and predictors for discontinuation of a second-line biologic.

Material And Methods: Non-interventional prospective study of RA patients exposed to a 2nd TNFi, TCZ or RTX after previous TNFi discontinuation using real-world data from Reuma.pt database. Read More

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February 2020
4 Reads
0.831 Impact Factor

Intraarticular injection of platelet-rich plasma in knee osteoarthritis: single versus triple application approach. Pilot study.

Acta Reumatol Port 2019 Apr-Jun;44(2):138-144

Universidad Autonoma de Nuevo Leon.

Objective: To compare the clinical effectiveness of the triple intra-articular injection of platelet-rich plasma (PRP) with respect to the single injection in patients with mild osteoarthritis of the knee.

Methods: A total of 35 patients with a clinical and radiographic diagnosis of osteoarthritis grade I and II were analyzed. They were randomized into two groups: single application (18 patients) and triple application (17 patients). Read More

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February 2020
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Positive affect as a predictor of adherence in patients with Rheumatoid Arthritis.

Acta Reumatol Port 2019 Apr-Jun;44(2):132-137

Unidade Local de Saúde do Alto Minho.

The study was conducted in order to investigate adherence in patients with Rheumatoid arthritis (RA), correlating it with other variables such as affect and self-esteem. Seventy-eight patients with RA between 20 and 81 years of age were evaluated. Patients were assessed for Medical Outcomes Study (MOS) Measures of Patient Adherence, Rosenberg self-esteem scale and Short Portuguese version of the Positive and Negative Affect Schedule (PANAS). Read More

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February 2020
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Haemophagocytic syndrome in Systemic Lupus Erythematosus - clues to an early diagnosis.

Acta Reumatol Port 2018 Oct-Dec;43(4):318-320

Centro Hospitalar São João.

Macrophage activation syndrome (MAS) is a rare life-threatening condition that involves excessive activation of inflammatory cells and overproduction of different cytokines. It is characterized by persistent fever, hepatosplenomegaly, cytopenias and coagulopathy. Other prominent features are hyperferritinemia and findings of activated macrophages in haemopoietic organs, often associated with multi-organ impairment. Read More

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August 2019
7 Reads