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    3609 results match your criteria Acta medica portuguesa[Journal]

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    [Endovascular Treatment of a Gastroduodenal Artery Pseudoaneurysm Rupture after a Car Accident].
    Acta Med Port 2017 Sep 29;30(9):658-661. Epub 2017 Sep 29.
    Unidade de Radiologia de Intervenção. Centro Hepato-Bilio-Pancreático e de Transplantação. Hospital Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
    The authors present a case of a 39-year-old man with alcoholic chronic pancreatitis that was admitted in the emergency department after a car accident, complaining of abdominal pain and looking pale. The patient was hemodinamically unstable, requiring blood transfusions. He underwent computed tomography angiogram of the abdomen and pelvis, showing a pseudoaneurysm of the gastroduodenal artery and a hemoperitoneum. Read More

    Negative βhCG and Molar Pregnancy: The Hook Effect.
    Acta Med Port 2017 Sep 29;30(9):656-658. Epub 2017 Sep 29.
    Gynaecology and Obstetrics Department. Hospital Garcia de Orta. Almada. Portugal.
    Molar pregnancy, included in gestational trophoblastic disease, is a benign pathology with ability to metastasize, usually occurring with excessively high βhCG levels. Clinical scenario is usually a woman in extremes of reproductive age presenting with amenorrhoea, pain and vaginal blood loss; signs derived from high βhCG levels may be present (hyperthyroidism, hyperemesis). Diagnosis is based on a positive pregnancy test - usually a qualitative urinary test. Read More

    Conflict of Interest Disclosure in a Top-Tier Portuguese Medical Journal.
    Acta Med Port 2017 Sep 29;30(9):652-655. Epub 2017 Sep 29.
    Serviço de Nefrologia. Hospital Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
    Introduction: Scientific medical publications are considered to be a source of unbiased and independent information. Authors are required to disclose relationships with the pharmaceutical industry for transparency purposes. The aim of this work was to assess conflict of interest disclosure in a Portuguese top-tier medical journal by comparing authors' self-reported conflicts of interest with payments listed in the official database of Portuguese Ministry of Health. Read More

    [Endocrinology in Portugal - Census 2016. Board of the Portuguese College of Endocrinology and Nutrition of the Portuguese Medical Association].
    Acta Med Port 2017 Sep 29;30(9):642-651. Epub 2017 Sep 29.
    Serviço de Endocrinologia. Hospital Santo António. Centro Hospitalar do Porto. Porto. Portugal.
    Introduction: On September 2016, the Board of the College of Endocrinology and Nutrition of the Portuguese Medical Association carried out a national survey, about all Endocrinology, Diabetes and Metabolism Departments of the public hospitals included in the Portuguese National Health Service and a simplified version of this survey was sent to all endocrinologists working in Portugal and registered with the Portuguese Medical Association.

    Material And Methods: Data related to organizational and human resources were collected, reporting the situation by the end of year 2015. The census registered 107 individuals and 27 Departments. Read More

    Intensive Follow-Up After Curative Surgery for Colorectal Cancer.
    Acta Med Port 2017 Sep 29;30(9):633-641. Epub 2017 Sep 29.
    Department of Gastroenterology. Instituto Português de Oncologia de Lisboa Francisco Gentil. Lisboa. Portugal.
    Introduction: The purpose of postoperative surveillance programs after curative treatment for colorectal cancer is to detect asymptomatic recurrences with the premise that an important rate will be eligible for curative resection, improving overall survival. We have implemented a surveillance program for patients with colorectal cancer, stages II-III, with periodic clinical, carcinoembryonic antigen and cancer antigen-19-9 assessment, computed tomography and colonoscopy. The aim of this study was to assess the rate of curative treatment of recurrence, colorectal cancer mortality and clinical characteristics associated with non-resectable recurrence. Read More

    [Volume or Value? The Role of the Radiologist in Managing Radiological Exams].
    Acta Med Port 2017 Sep 29;30(9):628-632. Epub 2017 Sep 29.
    Serviço de Imagiologia. Centro Hospitalar de Setúbal. Setúbal. Portugal.
    Introduction: The purpose of this study was to understand the reasons and quantify the number of ultrasounds and computed tomographies that are potentially wasted in the hospital emergency in our institution, and the importance that the radiologist can have in the management and screening of these exams.

    Material And Methods: It was decided that urgent tests that were pending for more than seven days would be the object of analysis as to why they were not performed, consulting the electronic medical records. Six causes were used to cancel the requests: 'Changing the patient's status', 'Patient's withdrawal, refusal or abandonment', 'Patient's death'; 'No criteria or contraindicated', 'Lack of human resources' and 'Mistaken request'. Read More

    [Evaluation of the Function and Quality of Life after Total Hip Arthroplasty by Different Approaches].
    Acta Med Port 2017 Sep 29;30(9):623-627. Epub 2017 Sep 29.
    Serviço de Medicina Física e de Reabilitação. Centro Hospitalar de Leiria. Leiria. Portugal.
    Introduction: To assess the function and quality of life in patients undergoing total hip arthroplasty distinguishing two surgical approaches (posterior / anterolateral) used by the Orthopedics department of Centro Hospitalar de Leiria.

    Material And Methods: Retrospective study of 94 patients subject to unilateral hip replacement surgery, using the 'Hip Osteoarthritis Outcome Score' (HOOS LK 2.0) questionnaire, the Trendelenburg test and evaluation of muscle strength of the hip abductor muscles with dynamometer. Read More

    [Being a Mother After 35 Years: Will it be Different?]
    Acta Med Port 2017 Sep 29;30(9):615-622. Epub 2017 Sep 29.
    Serviço de Neonatologia. Departamento de Pediatria. Hospital Universitário de Santa Maria. Centro Académico de Medicina de Lisboa. Lisboa. Portugal.
    Introduction: Advanced maternal age is defined as maternity after 35 years old and is associated with more complications during pregnancy and neonatal period as well as decreased fertility. This study aims to examine the relationship between advanced maternal age and their maternal and fetal consequences, as well as maternal perception of the risk of pregnancy after 35 years old.

    Material And Methods: Observational, retrospective and comparative study, between two groups: advanced maternal age group (aged ≥ 35 years) and non-advanced maternal age group (age < 35 years), conducted between March and June 2015. Read More

    Hospital-Acquired Urinary Tract Infections: Results of a Cohort Study Performed in an Internal Medicine Department.
    Acta Med Port 2017 Sep 29;30(9):608-614. Epub 2017 Sep 29.
    Escola Nacional de Saúde Pública. Centro de Investigação em Saúde Pública. Universidade de Nova de Lisboa. Lisboa. Portugal.
    Introduction: Urinary tract infections are the most frequent healthcare associated infections, being related to both high costs and morbidity. Our intention was to carry out an epidemiological characterization of hospital acquired urinary tract infections that occurred in an internal medicine department of a Portuguese hospital.

    Material And Methods: Retrospective cohort study (historic cohort). Read More

    [Translation and Validation of the FOUR Scale for Children and its Use as Outcome Predictor: A Pilot Study].
    Acta Med Port 2017 Sep 29;30(9):599-607. Epub 2017 Sep 29.
    Unidade de Cuidados Intensivos Pediátricos. Departamento de Pediatria. Hospital de Santa Maria. Centro Académico de Medicina de Lisboa. Lisboa. Portugal.
    Introduction: The Full Outline of UnResponsiveness - FOUR scale has been previously validated to assess impaired consciousness in the adult population. The aim of this study is the translation into Portuguese and validation of the FOUR scale in the pediatric population. The study also compares the FOUR scale and Glasgow coma scale score ratings and the clinical outcome of patients hospitalized in Pediatric Intensive Care Units. Read More

    [Neonatal Morbidity and Gestational Diabetes: Coincidence or Consequence of the 2011 Protocol].
    Acta Med Port 2017 Sep 29;30(9):589-598. Epub 2017 Sep 29.
    Departamento de Pediatria. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal; Unidade de Neurodesenvolvimento e Autismo do Centro de Desenvolvimento da Criança e Centro de Investigação e Formação Clínica. Hospital Pediátrico de Coimbra. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Introduction: Gestational diabetes is one of the diseases associated with pregnancy with higher rate of complications. Despite being a transitory condition, short and long term complications related to gestational diabetes have been described. There is scientific evidence to say that good metabolic control decreases perinatal complications. Read More

    Family Phenotypic Heterogeneity Caused by Mitochondrial DNA Mutation A3243G.
    Acta Med Port 2017 Aug 31;30(7-8):581-585. Epub 2017 Aug 31.
    Serviço de Medicina Interna. Hospital Amato Lusitano. Castelo Branco. Portugal.
    Maternally inherited diabetes and deafness is a rare form of diabetes caused by a mitochondrial DNA mutation. The index case is a 55-year-old woman who was admitted with hypertrophic cardiomyopathy. She had a history of diabetes mellitus and hearing loss. Read More

    Pneumonitis in Adult Onset Still's Disease: Uncommon or Under Diagnosed?
    Acta Med Port 2017 Aug 31;30(7-8):578-581. Epub 2017 Aug 31.
    Department of Rheumatology and Metabolic Bone Diseases. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisbon. Portugal.
    The adult onset Still's Disease is an uncommon entity characterized by multiple clinical manifestations. Pneumonitis, less often considered, deserves particular emphasis given the need for differential diagnosis and because it can progress to severe respiratory failure. With the aim to highlight the pulmonary parenchyma involvement in patients with adult onset Still's Disease, we present a case report which progresses with pneumonitis. Read More

    [Choroidal Melanoma].
    Acta Med Port 2017 Aug 31;30(7-8):573-577. Epub 2017 Aug 31.
    Serviço de Oftalmologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Choroidal melanoma is the most common primary intraocular malignant tumor in adults. None of the different treatments available offers advantages of survival, resorting more and more to conservative treatments such as brachytherapy, which has been available in Portugal since 2013. In this article we review the clinical characteristics, risk factors, diagnosis, complementary exams and therapeutic options in choroidal melanoma. Read More

    [Assessment of Urinary Incontinence in Pregnancy and Postpartum: Observational Study].
    Acta Med Port 2017 Aug 31;30(7-8):568-572. Epub 2017 Aug 31.
    Serviço de Ginecologia e Obstetrícia. Centro Hospitalar Tâmega e Sousa. Penafiel. Portugal.
    Introduction: The urinary incontinence can affect up to 50% of women at some stage of their lives, particularly during pregnancy and postpartum. This study was designed in order to identify and assess the prevalence and risk factors for urinary incontinence during the third trimester of pregnancy and three months postpartum.

    Material And Methods: Observational and cross-sectional study. Read More

    [Diabetes: Socioeconomic Inequalities in the Portuguese Population in 2014].
    Acta Med Port 2017 Aug 31;30(7-8):561-567. Epub 2017 Aug 31.
    Departamento de Epidemiologia. Instituto Nacional de Saúde Dr. Ricardo Jorge. Lisboa. Portugal.
    Introduction: Diabetes is a major public health problem and it is related to socioeconomic factors. The aim of this study is to describe socioeconomic inequalities in the distribution of diabetes in the population with 25 years or more, resident in Portugal in 2014.

    Material And Methods: Data from the Health National Survey 2014 was analysed, n = 16 786. Read More

    Postoperative Haematocrit and Outcome in Critically Ill Surgical Patients.
    Acta Med Port 2017 Aug 31;30(7-8):555-560. Epub 2017 Aug 31.
    Department of Anaesthesiology. Hospital de São João. Porto. Portugal; Department of Surgery. Anaesthesiology and Perioperative Medicine Unit. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: Haematocrit has been studied as an outcome predictor. The aim of this study was to evaluate the correlation between low haematocrit at surgical intensive care unit admission and high disease scoring system score and early outcomes.

    Material And Methods: This retrospective study included 4398 patients admitted to the surgical intensive care unit between January 2006 and July 2013. Read More

    [Morbidity in the Dependent Elderly Cared by Home-Teams of the National Network of Continued Integrated Care in the Lisbon and Tagus Valley: Cross-Sectional Study].
    Acta Med Port 2017 Aug 31;30(7-8):546-554. Epub 2017 Aug 31.
    Unidade de Cuidados de Saúde Primários dos Olivais. Agrupamento de Centros de Saúde de Lisboa Central. Lisboa. Portugal; Departamento de Saúde Pública. Escola Nacional de Saúde Pública. Universidade Nova de Lisboa. Lisboa. Portugal; Departamento de Medicina Geral e Familiar. Faculdade de Medicina de Lisboa. Universidade de Lisboa. Lisboa. Portugal.
    Introduction: In Portugal, the National Network of Continuing Integrated Care's mission is to take care of new health and social needs. The aim of the study was to know the disease burden and disability of the elderly (75 and over) cared by the integrated continuing care teams.

    Material And Methods: A cross-sectional study carried out in a sample of 230 participants, from 25 teams randomly selected in the region of Lisbon and Tagus Valley. Read More

    Long-Term Outcomes of the Calcaneo-Stop Procedure in the Treatment of Flexible Flatfoot in Children: A Retrospective Study.
    Acta Med Port 2017 Aug 31;30(7-8):541-545. Epub 2017 Aug 31.
    Unidade de Ortopedia e Traumatologia. Departamento de Cirurgia. Faculdade de Medicina. Universidade do Porto. Porto. Portugal; Departamento de Ortopedia e Traumatologia. Centro Hospitalar de São João. Porto. Portugal.
    Introduction: Flexible flatfoot is common amongst children, although treatment is rarely indicated. The calcaneo-stop procedure has been reported to be effective in short-term studies. We aim to evaluate the long-term outcomes of the calcaneo-stop procedure in the treatment of flexible flatfoot in children. Read More

    Prevalence of Hepatitis A Virus Antibody in Portuguese Travelers: A New Paradigm.
    Acta Med Port 2017 Aug 31;30(7-8):534-540. Epub 2017 Aug 31.
    Serviço de Doenças Infeciosas. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Introduction: In Portugal, the prevalence of hepatitis A virus infection has decreased in the past decades, especially in young adults. The aim of this study was to detect the prevalence of antibody to hepatitis A virus in a population observed in our Travel Clinic.

    Material And Methods: Antibodies against hepatitis A, hepatitis B, hepatitis C and human immunodeficiency virus were tested using standard enzyme immunoassay in patients older than 18. Read More

    [Epidemiology of Internet Use by an Adolescent Population and its Relation with Sleep Habits].
    Acta Med Port 2017 Aug 31;30(7-8):524-533. Epub 2017 Aug 31.
    Serviço de Pediatria. Hospital da Senhora da Oliveira. Guimarães. Portugal.
    Introduction: In the last decades, the great technological development increased Internet popularity, emerging the concern about its overuse. The objectives of this study were to assess and characterize Internet use in adolescence, determine Internet addiction and clarify its association with sleep disorders and excessive daytime sleepiness.

    Material And Methods: It was performed an observational, cross sectional and community-based study. Read More

    [Analysis of the Cochrane Review: Anti-vascular Endothelial Growth Factor for Prevention of Postoperative Vitreous Cavity Hemorrhage after Vitrectomy for Proliferative Diabetic Retinopathy. Cochrane Database Syst Rev. 2015;8:CD008214.]
    Acta Med Port 2017 Aug 31;30(7-8):513-516. Epub 2017 Aug 31.
    Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Cochrane Portugal. Lisboa. Portugal.
    Postoperative vitreous hemorrhage is a complication following vitrectomy for proliferative diabetic retinopathy, delaying visual recovery and making fundus examination and disease follow-up more difficult. Anti-vascular endothelial growth factor drugs such as bevacizumab, when injected in the vitreous cavity, reduce vascular proliferation and their use has been proposed to reduce the incidence of postoperative vitreous hemorrhage. The authors of this Cochrane systematic review evaluated all randomized controlled trials on the pre- or intraoperative use of anti-vascular endothelial growth factor to reduce postoperative vitreous hemorrhage occurrence after vitrectomy in patients with proliferative diabetic retinopathy. Read More

    [Investigation of Genetic Aetiology in Neurodegenerative Ataxias: Recommendations from the Group of Neurogenetics of Centro Hospitalar São João, Portugal].
    Acta Med Port 2017 Jun 30;30(6):502-512. Epub 2017 Jun 30.
    Unidade de Neuropediatria. Serviço de Pediatria. Centro Hospitalar São João. Porto. Portugal; Serviço de Genética. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    In recent decades, a long and increasing list of monogenic neurodegenerative ataxias has been identified, allowing for better characterization of the pathophysiology, phenotype and prognosis of this heterogeneous group of disorders, while also revealing potential new therapeutic targets. However, the heterogeneity and complexity of the genotype-phenotype relationships and the high costs of molecular genetics often make it difficult for clinicians to decide on a molecular investigation based on an unbiased rational plan. Clinical history is essential to guide the diagnostic workup, but often the phenotype does not hold enough specificity to allow for predicting the genotype. Read More

    [Klebsiella pneumoniae from K1 and Hypervirulent Clone ST23: First Documented Case in Portugal].
    Acta Med Port 2017 Jun 30;30(6):496-499. Epub 2017 Jun 30.
    Unidade Laboratorial Integrada. Departamento de Doenças Infecciosas. Instituto Nacional de Saúde Doutor Ricardo Jorge. Lisboa. Portugal.
    The hypervirulent K1 serotype Klebsiella pneumoniae is responsible for a new invasive syndrome, typically associated to hepatic abscesses with extra-hepatic complications. Initially described in Taiwan, it has significantly spread to several Asian countries and more recently to Europe and North America, thus constituting an emerging and global problem. The authors describe a case report of a 64-years-old portuguese caucasian woman without any previous diseases or epidemiological risk factors such as trips or contact with Asian products or population, diagnosed with a pyogenic liver abscess with pleural effusion caused by this hyper-virulent strain. Read More

    [Secondary Arterial Hypertension: Uncertainties in Diagnosis].
    Acta Med Port 2017 Jun 30;30(6):493-496. Epub 2017 Jun 30.
    Serviço de Cardiologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Arterial hypertension is regarded today as a global public health problem, and the prevalence rate in Portugal is 26.9%. According to the etiology, is classified into primary or secondary arterial hypertension. Read More

    The Calcium/Phosphorus Homeostasis in Chronic Kidney Disease: From Clinical Epidemiology to Pathophysiology.
    Acta Med Port 2017 Jun 30;30(6):485-492. Epub 2017 Jun 30.
    Laboratório de Fisiologia. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto. Portugal.
    Introduction: A simple data filtering process together with some basic concepts of control theory applied to electronically stored clinical data were used to identify some of the pathophysiological mechanisms underlying the perturbations of the calcium/phosphorus homeostasis in chronic kidney disease.

    Material And Methods: Retrospective data (a set per patient of serum single value concentrations of creatinine, calcium, phosphorus, parathormone, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D) from 2507 patients with stable chronic kidney disease not on renal replacement therapy were studied. The variables were paired and subjected sequentially to a moving average and partioned into frequency classes. Read More

    Breech Presentation: Vaginal Versus Cesarean Delivery, Which Intervention Leads to the Best Outcomes?
    Acta Med Port 2017 Jun 30;30(6):479-484. Epub 2017 Jun 30.
    Departamento de Obstetrícia e Ginecologia. Hospital de Santa Maria. Centro Hospital Lisboa Norte. Lisboa. Portugal.
    Introduction: The best route of delivery for the term breech fetus is still controversial. We aim to compare maternal and neonatal outcomes between vaginal and cesarean term breech deliveries.

    Material And Methods: Multicentric retrospective cohort study of singleton term breech fetuses delivered vaginally or by elective cesarean section from January 2012 - October 2014. Read More

    [Fine-needle Aspiration of Thyroid Nodules: Is it Worth Repeating?]
    Acta Med Port 2017 Jun 30;30(6):472-478. Epub 2017 Jun 30.
    IPATIMUP Diagnósticos. Instituto de Patologia e Imunologia Molecular. Universidade do Porto. Porto. Portugal; Departamento de Patologia. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: The fine-needle aspiration has a significant role in assessing the malignancy risk of thyroid nodules. There is uncertainty regarding the value of repeat fine-needle aspiration in benign nodules. This study aims to evaluate the concordance of results in consecutive fine-needle aspiration and to study the relevance of repetition in benign results. Read More

    Functional, Sensorial, Mobility and Communication Difficulties in the Portuguese Oldest Old (80+).
    Acta Med Port 2017 Jun 30;30(6):463-471. Epub 2017 Jun 30.
    Research and Education Unit on Ageing. Universidade do Porto. Porto. Portugal; Center for Health Technology and Services Research. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: The ageing of populations is evident in most developed countries, and the oldest old group is one of the segments with the fastest growing. The aim of this paper is to examine sociodemographic and health related characteristics of the portuguese oldest old, using a census-based approach.

    Material And Methods: A descriptive study considering all residents aged 80 years and older at the time of the 2011 Census (n = 532 219) was conducted. Read More

    [Paediatric Invasive Pneumococcal Disease Before Universal Vaccination: 1995 - 2015].
    Acta Med Port 2017 Jun 30;30(6):457-462. Epub 2017 Jun 30.
    Unidade de Infeciologia e Serviço de Urgência. Hospital Pediátrico. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal; Departamento de Pediatria. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    Introduction: Pneumococcal conjugate vaccine was introduced in the private market in Portugal in 2001, reaching over the years a moderately high coverage. In July 2015, it was included in the National Immunisation Program. The aim of this study was to characterize invasive pneumococcal disease in a pediatric hospital before universal use of the vaccine. Read More

    A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patients with Wet Age-Related Macular Degeneration from Portugal.
    Acta Med Port 2017 Jun 30;30(6):449-456. Epub 2017 Jun 30.
    Department of Ophthalmology. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
    Introduction: Anti-vascular endothelial growth factor therapy has revolutionized the treatment of wet age-related macular degeneration; however, it is important to monitor actual use of ranibizumab and related treatment outcomes in routine practice.

    Material And Methods: This was a retrospective, observational study to monitor the 2-year outcomes following ranibizumab treatment for wet age-related macular degeneration in Portugal. Patients treated between January 2009 and December 2009 were retrospectively evaluated. Read More

    [Visceral Leishmaniasis in HIV-Infected Patients: The Challenge of Relapse and Treatment Failure].
    Acta Med Port 2017 Jun 30;30(6):443-448. Epub 2017 Jun 30.
    Serviço de Infeciologia. Hospital de Egas Moniz. Centro Hospitalar Lisboa Ocidental. Lisboa. Portugal.
    Introduction: Visceral leishmaniasis is an endemic disseminated infection, considered to be the third most frequent opportunistic parasitic infection in Europe. It is especially prevalent in patients co-infected with human immunodeficiency virus, in whom it poses a great therapeutic challenge due to increased risk of relapse. The goal of this study is to characterize a population of co-infected patients, as well as the efficiency of the adopted treatment strategies. Read More

    [Diabetes Screening in Patients with Macrovascular Coronary Disease: Are the New European Guidelines a Step Backwards?]
    Acta Med Port 2017 Jun 30;30(6):434-442. Epub 2017 Jun 30.
    Serviço de Cardiologia. Hospital Fernando Fonseca. Amadora. Portugal.
    Background: The new European guidelines on diabetes mellitus and cardiovascular diseases propose that the FINnish Diabetes RIsk SCore should be used to evaluate the risk of diabetes mellitus and that diabetes mellitus screening in coronary artery disease patients should be based on fasting glucose and HbA1c. The 2 hour oral glucose tolerance test, recommended for all pts in the previous guidelines, is now only recommended for 'inconclusive' cases. We aimed to evaluate this new strategy. Read More

    Carcinoid Syndrome and Carcinoid Heart Disease as Manifestations of Non-Metastatic Ovarian Neuroendocrine Tumour.
    Acta Med Port 2017 May 31;30(5):421-425. Epub 2017 May 31.
    Oxford Centre for Diabetes, Endocrinology and Metabolism. Churchill Hospital. Oxford. United Kingdom.
    The carcinoid syndrome is rare but it is associated with carcinoid heart disease in more than a half of the cases. Carcinoid heart disease is typically characterised by morphological and functional modifications of right-sided valves. Its aetiology is probable multifactorial but serotonin appears to play a key role in the development of this valvular disease. Read More

    [Gorlin-Goltz Syndrome: Diagnosis and Treatment Options].
    Acta Med Port 2017 May 31;30(5):418-421. Epub 2017 May 31.
    Serviço de Dermatologia e Venereologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal. Departamento de Dermatologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    The Gorlin-Goltz syndrome is a rare autosomal dominant hereditary condition, with complete penetrance and variable expressivity. Characterized by the appearance of multiple basaliomas, and often the development of keratocyst, it can also express itself by the presence of palmar/plantar depressions, calcification of brain sickle, and skeletal birth defects, although less frequently. This article presents two cases involving direct relatives, referred after the identification of several basaliomas and jaw cysts. Read More

    [Anaerobic Bacteria with Clinical Relevance: Morphologic and Taxonomic Classification, Distribution among Human Microbiota and Microbiologic Diagnosis].
    Acta Med Port 2017 May 31;30(5):409-417. Epub 2017 May 31.
    Serviço de Infeciologia e Medicina Tropical. Hospital de Egas Moniz. Centro Hospitalar de Lisboa Ocidental. Lisboa. Portugal. Unidade de Infeção: Etiologia, Patogénese e Bases Terapêuticas. Faculdade de Ciências Médicas. Universidade NOVA de Lisboa. Lisboa. Portugal.
    The wide burden of anaerobic bacteria colonizing human body comprises about 90% of its total biomass. The biotic relationship between humans and its microbiota sets reciprocal benefits, albeit with pathogenic potencial for the human being in particular dysbiosis situations. Infections adjacent to or originating from the skin or mucous membranes of the intestinal, genitourinary and upper respiratory tracts are often polymicrobial in nature, whereby should anaerobes be invariably included in the etiological differential diagnosis of these conditions. Read More

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