Acta Med Port 2017 Jun 30;30(6):485-492. Epub 2017 Jun 30.
Laboratório de Fisiologia. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto. Portugal.
: A simple data filtering process together with some basic concepts of control theory applied to electronically stored clinical data were used to identify some of the pathophysiological mechanisms underlying the perturbations of the calcium/phosphorus homeostasis in chronic kidney disease.Material And Methods
: Retrospective data (a set per patient of serum single value concentrations of creatinine, calcium, phosphorus, parathormone, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D) from 2507 patients with stable chronic kidney disease not on renal replacement therapy were studied. The variables were paired and subjected sequentially to a moving average and partioned into frequency classes. Read More