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    3594 results match your criteria Acta medica portuguesa[Journal]

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    Family Phenotypic Heterogeneity Caused by Mitochondrial DNA Mutation A3243G.
    Acta Med Port 2017 Aug 31;30(7-8):581-585. Epub 2017 Aug 31.
    Serviço de Medicina Interna. Hospital Amato Lusitano. Castelo Branco. Portugal.
    Maternally inherited diabetes and deafness is a rare form of diabetes caused by a mitochondrial DNA mutation. The index case is a 55-year-old woman who was admitted with hypertrophic cardiomyopathy. She had a history of diabetes mellitus and hearing loss. Read More

    Pneumonitis in Adult Onset Still's Disease: Uncommon or Under Diagnosed?
    Acta Med Port 2017 Aug 31;30(7-8):578-581. Epub 2017 Aug 31.
    Department of Rheumatology and Metabolic Bone Diseases. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisbon. Portugal.
    The adult onset Still's Disease is an uncommon entity characterized by multiple clinical manifestations. Pneumonitis, less often considered, deserves particular emphasis given the need for differential diagnosis and because it can progress to severe respiratory failure. With the aim to highlight the pulmonary parenchyma involvement in patients with adult onset Still's Disease, we present a case report which progresses with pneumonitis. Read More

    [Choroidal Melanoma].
    Acta Med Port 2017 Aug 31;30(7-8):573-577. Epub 2017 Aug 31.
    Serviço de Oftalmologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Choroidal melanoma is the most common primary intraocular malignant tumor in adults. None of the different treatments available offers advantages of survival, resorting more and more to conservative treatments such as brachytherapy, which has been available in Portugal since 2013. In this article we review the clinical characteristics, risk factors, diagnosis, complementary exams and therapeutic options in choroidal melanoma. Read More

    [Assessment of Urinary Incontinence in Pregnancy and Postpartum: Observational Study].
    Acta Med Port 2017 Aug 31;30(7-8):568-572. Epub 2017 Aug 31.
    Serviço de Ginecologia e Obstetrícia. Centro Hospitalar Tâmega e Sousa. Penafiel. Portugal.
    Introduction: The urinary incontinence can affect up to 50% of women at some stage of their lives, particularly during pregnancy and postpartum. This study was designed in order to identify and assess the prevalence and risk factors for urinary incontinence during the third trimester of pregnancy and three months postpartum.

    Material And Methods: Observational and cross-sectional study. Read More

    [Diabetes: Socioeconomic Inequalities in the Portuguese Population in 2014].
    Acta Med Port 2017 Aug 31;30(7-8):561-567. Epub 2017 Aug 31.
    Departamento de Epidemiologia. Instituto Nacional de Saúde Dr. Ricardo Jorge. Lisboa. Portugal.
    Introduction: Diabetes is a major public health problem and it is related to socioeconomic factors. The aim of this study is to describe socioeconomic inequalities in the distribution of diabetes in the population with 25 years or more, resident in Portugal in 2014.

    Material And Methods: Data from the Health National Survey 2014 was analysed, n = 16 786. Read More

    Postoperative Haematocrit and Outcome in Critically Ill Surgical Patients.
    Acta Med Port 2017 Aug 31;30(7-8):555-560. Epub 2017 Aug 31.
    Department of Anaesthesiology. Hospital de São João. Porto. Portugal; Department of Surgery. Anaesthesiology and Perioperative Medicine Unit. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: Haematocrit has been studied as an outcome predictor. The aim of this study was to evaluate the correlation between low haematocrit at surgical intensive care unit admission and high disease scoring system score and early outcomes.

    Material And Methods: This retrospective study included 4398 patients admitted to the surgical intensive care unit between January 2006 and July 2013. Read More

    [Morbidity in the Dependent Elderly Cared by Home-Teams of the National Network of Continued Integrated Care in the Lisbon and Tagus Valley: Cross-Sectional Study].
    Acta Med Port 2017 Aug 31;30(7-8):546-554. Epub 2017 Aug 31.
    Unidade de Cuidados de Saúde Primários dos Olivais. Agrupamento de Centros de Saúde de Lisboa Central. Lisboa. Portugal; Departamento de Saúde Pública. Escola Nacional de Saúde Pública. Universidade Nova de Lisboa. Lisboa. Portugal; Departamento de Medicina Geral e Familiar. Faculdade de Medicina de Lisboa. Universidade de Lisboa. Lisboa. Portugal.
    Introduction: In Portugal, the National Network of Continuing Integrated Care's mission is to take care of new health and social needs. The aim of the study was to know the disease burden and disability of the elderly (75 and over) cared by the integrated continuing care teams.

    Material And Methods: A cross-sectional study carried out in a sample of 230 participants, from 25 teams randomly selected in the region of Lisbon and Tagus Valley. Read More

    Long-Term Outcomes of the Calcaneo-Stop Procedure in the Treatment of Flexible Flatfoot in Children: A Retrospective Study.
    Acta Med Port 2017 Aug 31;30(7-8):541-545. Epub 2017 Aug 31.
    Unidade de Ortopedia e Traumatologia. Departamento de Cirurgia. Faculdade de Medicina. Universidade do Porto. Porto. Portugal; Departamento de Ortopedia e Traumatologia. Centro Hospitalar de São João. Porto. Portugal.
    Introduction: Flexible flatfoot is common amongst children, although treatment is rarely indicated. The calcaneo-stop procedure has been reported to be effective in short-term studies. We aim to evaluate the long-term outcomes of the calcaneo-stop procedure in the treatment of flexible flatfoot in children. Read More

    Prevalence of Hepatitis A Virus Antibody in Portuguese Travelers: A New Paradigm.
    Acta Med Port 2017 Aug 31;30(7-8):534-540. Epub 2017 Aug 31.
    Serviço de Doenças Infeciosas. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Introduction: In Portugal, the prevalence of hepatitis A virus infection has decreased in the past decades, especially in young adults. The aim of this study was to detect the prevalence of antibody to hepatitis A virus in a population observed in our Travel Clinic.

    Material And Methods: Antibodies against hepatitis A, hepatitis B, hepatitis C and human immunodeficiency virus were tested using standard enzyme immunoassay in patients older than 18. Read More

    [Epidemiology of Internet Use by an Adolescent Population and its Relation with Sleep Habits].
    Acta Med Port 2017 Aug 31;30(7-8):524-533. Epub 2017 Aug 31.
    Serviço de Pediatria. Hospital da Senhora da Oliveira. Guimarães. Portugal.
    Introduction: In the last decades, the great technological development increased Internet popularity, emerging the concern about its overuse. The objectives of this study were to assess and characterize Internet use in adolescence, determine Internet addiction and clarify its association with sleep disorders and excessive daytime sleepiness.

    Material And Methods: It was performed an observational, cross sectional and community-based study. Read More

    [Analysis of the Cochrane Review: Anti-vascular Endothelial Growth Factor for Prevention of Postoperative Vitreous Cavity Hemorrhage after Vitrectomy for Proliferative Diabetic Retinopathy. Cochrane Database Syst Rev. 2015;8:CD008214.]
    Acta Med Port 2017 Aug 31;30(7-8):513-516. Epub 2017 Aug 31.
    Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Cochrane Portugal. Lisboa. Portugal.
    Postoperative vitreous hemorrhage is a complication following vitrectomy for proliferative diabetic retinopathy, delaying visual recovery and making fundus examination and disease follow-up more difficult. Anti-vascular endothelial growth factor drugs such as bevacizumab, when injected in the vitreous cavity, reduce vascular proliferation and their use has been proposed to reduce the incidence of postoperative vitreous hemorrhage. The authors of this Cochrane systematic review evaluated all randomized controlled trials on the pre- or intraoperative use of anti-vascular endothelial growth factor to reduce postoperative vitreous hemorrhage occurrence after vitrectomy in patients with proliferative diabetic retinopathy. Read More

    [Investigation of Genetic Aetiology in Neurodegenerative Ataxias: Recommendations from the Group of Neurogenetics of Centro Hospitalar São João, Portugal].
    Acta Med Port 2017 Jun 30;30(6):502-512. Epub 2017 Jun 30.
    Unidade de Neuropediatria. Serviço de Pediatria. Centro Hospitalar São João. Porto. Portugal; Serviço de Genética. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    In recent decades, a long and increasing list of monogenic neurodegenerative ataxias has been identified, allowing for better characterization of the pathophysiology, phenotype and prognosis of this heterogeneous group of disorders, while also revealing potential new therapeutic targets. However, the heterogeneity and complexity of the genotype-phenotype relationships and the high costs of molecular genetics often make it difficult for clinicians to decide on a molecular investigation based on an unbiased rational plan. Clinical history is essential to guide the diagnostic workup, but often the phenotype does not hold enough specificity to allow for predicting the genotype. Read More

    [Klebsiella pneumoniae from K1 and Hypervirulent Clone ST23: First Documented Case in Portugal].
    Acta Med Port 2017 Jun 30;30(6):496-499. Epub 2017 Jun 30.
    Unidade Laboratorial Integrada. Departamento de Doenças Infecciosas. Instituto Nacional de Saúde Doutor Ricardo Jorge. Lisboa. Portugal.
    The hypervirulent K1 serotype Klebsiella pneumoniae is responsible for a new invasive syndrome, typically associated to hepatic abscesses with extra-hepatic complications. Initially described in Taiwan, it has significantly spread to several Asian countries and more recently to Europe and North America, thus constituting an emerging and global problem. The authors describe a case report of a 64-years-old portuguese caucasian woman without any previous diseases or epidemiological risk factors such as trips or contact with Asian products or population, diagnosed with a pyogenic liver abscess with pleural effusion caused by this hyper-virulent strain. Read More

    [Secondary Arterial Hypertension: Uncertainties in Diagnosis].
    Acta Med Port 2017 Jun 30;30(6):493-496. Epub 2017 Jun 30.
    Serviço de Cardiologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
    Arterial hypertension is regarded today as a global public health problem, and the prevalence rate in Portugal is 26.9%. According to the etiology, is classified into primary or secondary arterial hypertension. Read More

    The Calcium/Phosphorus Homeostasis in Chronic Kidney Disease: From Clinical Epidemiology to Pathophysiology.
    Acta Med Port 2017 Jun 30;30(6):485-492. Epub 2017 Jun 30.
    Laboratório de Fisiologia. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto. Portugal.
    Introduction: A simple data filtering process together with some basic concepts of control theory applied to electronically stored clinical data were used to identify some of the pathophysiological mechanisms underlying the perturbations of the calcium/phosphorus homeostasis in chronic kidney disease.

    Material And Methods: Retrospective data (a set per patient of serum single value concentrations of creatinine, calcium, phosphorus, parathormone, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D) from 2507 patients with stable chronic kidney disease not on renal replacement therapy were studied. The variables were paired and subjected sequentially to a moving average and partioned into frequency classes. Read More

    Breech Presentation: Vaginal Versus Cesarean Delivery, Which Intervention Leads to the Best Outcomes?
    Acta Med Port 2017 Jun 30;30(6):479-484. Epub 2017 Jun 30.
    Departamento de Obstetrícia e Ginecologia. Hospital de Santa Maria. Centro Hospital Lisboa Norte. Lisboa. Portugal.
    Introduction: The best route of delivery for the term breech fetus is still controversial. We aim to compare maternal and neonatal outcomes between vaginal and cesarean term breech deliveries.

    Material And Methods: Multicentric retrospective cohort study of singleton term breech fetuses delivered vaginally or by elective cesarean section from January 2012 - October 2014. Read More

    [Fine-needle Aspiration of Thyroid Nodules: Is it Worth Repeating?]
    Acta Med Port 2017 Jun 30;30(6):472-478. Epub 2017 Jun 30.
    IPATIMUP Diagnósticos. Instituto de Patologia e Imunologia Molecular. Universidade do Porto. Porto. Portugal; Departamento de Patologia. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: The fine-needle aspiration has a significant role in assessing the malignancy risk of thyroid nodules. There is uncertainty regarding the value of repeat fine-needle aspiration in benign nodules. This study aims to evaluate the concordance of results in consecutive fine-needle aspiration and to study the relevance of repetition in benign results. Read More

    Functional, Sensorial, Mobility and Communication Difficulties in the Portuguese Oldest Old (80+).
    Acta Med Port 2017 Jun 30;30(6):463-471. Epub 2017 Jun 30.
    Research and Education Unit on Ageing. Universidade do Porto. Porto. Portugal; Center for Health Technology and Services Research. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
    Introduction: The ageing of populations is evident in most developed countries, and the oldest old group is one of the segments with the fastest growing. The aim of this paper is to examine sociodemographic and health related characteristics of the portuguese oldest old, using a census-based approach.

    Material And Methods: A descriptive study considering all residents aged 80 years and older at the time of the 2011 Census (n = 532 219) was conducted. Read More

    [Paediatric Invasive Pneumococcal Disease Before Universal Vaccination: 1995 - 2015].
    Acta Med Port 2017 Jun 30;30(6):457-462. Epub 2017 Jun 30.
    Unidade de Infeciologia e Serviço de Urgência. Hospital Pediátrico. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal; Departamento de Pediatria. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    Introduction: Pneumococcal conjugate vaccine was introduced in the private market in Portugal in 2001, reaching over the years a moderately high coverage. In July 2015, it was included in the National Immunisation Program. The aim of this study was to characterize invasive pneumococcal disease in a pediatric hospital before universal use of the vaccine. Read More

    A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patients with Wet Age-Related Macular Degeneration from Portugal.
    Acta Med Port 2017 Jun 30;30(6):449-456. Epub 2017 Jun 30.
    Department of Ophthalmology. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
    Introduction: Anti-vascular endothelial growth factor therapy has revolutionized the treatment of wet age-related macular degeneration; however, it is important to monitor actual use of ranibizumab and related treatment outcomes in routine practice.

    Material And Methods: This was a retrospective, observational study to monitor the 2-year outcomes following ranibizumab treatment for wet age-related macular degeneration in Portugal. Patients treated between January 2009 and December 2009 were retrospectively evaluated. Read More

    [Visceral Leishmaniasis in HIV-Infected Patients: The Challenge of Relapse and Treatment Failure].
    Acta Med Port 2017 Jun 30;30(6):443-448. Epub 2017 Jun 30.
    Serviço de Infeciologia. Hospital de Egas Moniz. Centro Hospitalar Lisboa Ocidental. Lisboa. Portugal.
    Introduction: Visceral leishmaniasis is an endemic disseminated infection, considered to be the third most frequent opportunistic parasitic infection in Europe. It is especially prevalent in patients co-infected with human immunodeficiency virus, in whom it poses a great therapeutic challenge due to increased risk of relapse. The goal of this study is to characterize a population of co-infected patients, as well as the efficiency of the adopted treatment strategies. Read More

    [Diabetes Screening in Patients with Macrovascular Coronary Disease: Are the New European Guidelines a Step Backwards?]
    Acta Med Port 2017 Jun 30;30(6):434-442. Epub 2017 Jun 30.
    Serviço de Cardiologia. Hospital Fernando Fonseca. Amadora. Portugal.
    Background: The new European guidelines on diabetes mellitus and cardiovascular diseases propose that the FINnish Diabetes RIsk SCore should be used to evaluate the risk of diabetes mellitus and that diabetes mellitus screening in coronary artery disease patients should be based on fasting glucose and HbA1c. The 2 hour oral glucose tolerance test, recommended for all pts in the previous guidelines, is now only recommended for 'inconclusive' cases. We aimed to evaluate this new strategy. Read More

    Carcinoid Syndrome and Carcinoid Heart Disease as Manifestations of Non-Metastatic Ovarian Neuroendocrine Tumour.
    Acta Med Port 2017 May 31;30(5):421-425. Epub 2017 May 31.
    Oxford Centre for Diabetes, Endocrinology and Metabolism. Churchill Hospital. Oxford. United Kingdom.
    The carcinoid syndrome is rare but it is associated with carcinoid heart disease in more than a half of the cases. Carcinoid heart disease is typically characterised by morphological and functional modifications of right-sided valves. Its aetiology is probable multifactorial but serotonin appears to play a key role in the development of this valvular disease. Read More

    [Gorlin-Goltz Syndrome: Diagnosis and Treatment Options].
    Acta Med Port 2017 May 31;30(5):418-421. Epub 2017 May 31.
    Serviço de Dermatologia e Venereologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal. Departamento de Dermatologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    The Gorlin-Goltz syndrome is a rare autosomal dominant hereditary condition, with complete penetrance and variable expressivity. Characterized by the appearance of multiple basaliomas, and often the development of keratocyst, it can also express itself by the presence of palmar/plantar depressions, calcification of brain sickle, and skeletal birth defects, although less frequently. This article presents two cases involving direct relatives, referred after the identification of several basaliomas and jaw cysts. Read More

    [Anaerobic Bacteria with Clinical Relevance: Morphologic and Taxonomic Classification, Distribution among Human Microbiota and Microbiologic Diagnosis].
    Acta Med Port 2017 May 31;30(5):409-417. Epub 2017 May 31.
    Serviço de Infeciologia e Medicina Tropical. Hospital de Egas Moniz. Centro Hospitalar de Lisboa Ocidental. Lisboa. Portugal. Unidade de Infeção: Etiologia, Patogénese e Bases Terapêuticas. Faculdade de Ciências Médicas. Universidade NOVA de Lisboa. Lisboa. Portugal.
    The wide burden of anaerobic bacteria colonizing human body comprises about 90% of its total biomass. The biotic relationship between humans and its microbiota sets reciprocal benefits, albeit with pathogenic potencial for the human being in particular dysbiosis situations. Infections adjacent to or originating from the skin or mucous membranes of the intestinal, genitourinary and upper respiratory tracts are often polymicrobial in nature, whereby should anaerobes be invariably included in the etiological differential diagnosis of these conditions. Read More

    [Prevalence of Dental Caries in Patients with Type 1 Diabetes Mellitus Treated with Multiple Insulin Injections and that of Individuals without Diabetes].
    Acta Med Port 2017 May 31;30(5):402-408. Epub 2017 May 31.
    Área de Medicina Dentária. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal. Instituto Biomédico de Investigação de Luz e Imagem. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    Introduction: In addition to macro and microvascular complications that are associated with the disease, hyperglycaemia is also a risk factor for several oral complications. The aim of this study is to establish a relationship between dental caries in patients with type 1 diabetes mellitus treated with multiple insulin injections and that of individuals without diabetes. It is also an aim to characterize the oral hygiene habits of this population. Read More

    Reliability and Validity of 39-Item Parkinson's Disease Questionnaire and Parkinson's Disease Quality of Life Questionnaire.
    Acta Med Port 2017 May 31;30(5):395-401. Epub 2017 May 31.
    Neurology Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    Introduction: Parkinson's disease has a significant impact in quality of life, which can be assessed with 39-item Parkinson's Disease Questionnaire and Parkinson's Disease Quality of Life Questionnaire. This study aimed to evaluate the reliability and validity of these scales in Portuguese patients.

    Material And Methods: Reliability was assessed through internal consistency (Cronbach's alpha) and reproducibility (intraclass correlation coefficient). Read More

    Virtual Reality Simulation as a Tool to Monitor Surgical Performance Indicators: VIRESI Observational Study.
    Acta Med Port 2017 May 31;30(5):388-394. Epub 2017 May 31.
    General Surgery Department. Centro Hospitalar de São João. Porto. Portugal.
    Introduction: Virtual reality simulation is a topic of discussion as a complementary tool to traditional laparoscopic surgical training in the operating room. However, it is unclear whether virtual reality training can have an impact on the surgical performance of advanced laparoscopic procedures. Our objective was to assess the ability of the virtual reality simulator LAP Mentor to identify and quantify changes in surgical performance indicators, after LAP Mentor training for digestive anastomosis. Read More

    [Validation of the Otitis Media-6 Questionnaire for European Portuguese].
    Acta Med Port 2017 May 31;30(5):381-387. Epub 2017 May 31.
    Serviço de Otorrinolaringologia. Hospital de Egas Moniz. Centro Hospitalar de Lisboa Ocidental. Lisboa. Portugal. Departamento de Otorrinolaringologia. NOVA Medical School. Universidade Nova de Lisboa. Lisboa. Portugal.
    Introduction: Otitis media is one of the most prevalent childhood diseases. The impact of otitis media on quality of life of Portuguese children is unknown, because of the unavailability of a tool validated in European Portuguese to assess this consequence of otitis media. The Otitis Media-6 questionnaire (Otitis Media-6) is the most frequently used tool to assess health-related quality of life in children with otitis media. Read More

    Female Psychological Adjustment Following an Acute Coronary Syndrome.
    Acta Med Port 2017 May 31;30(5):373-380. Epub 2017 May 31.
    Microenvironments for New Therapies Group. Instituto de Investigação e Inovação em Saúde. University of Porto. Porto. Portugal. Department of Clinical Neurosciences and Mental Health. Faculty of Medicine. University of Porto. Porto. Portugal.
    Introduction: The outcomes of cardiovascular disease are consistently worse among women, regardless of age or disease severity. Such trend might arise from psychosocial factors, which should be examined in this population. Obective: To evaluate the influence of type-D personality on anxiety and depression symptoms reported by female patients after a first acute coronary syndrome. Read More

    [Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus].
    Acta Med Port 2017 May 31;30(5):368-372. Epub 2017 May 31.
    Unidade de Doenças Auto-imunes. Serviço Medicina 7.2. Hospital Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal; MBBCh, PhD, FRCP (UK), Responsável Unidade de Doenças Auto-imunes/Serviço Medicina 7.2, Hospital Curry Cabral, CHLC.
    Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease's prognosis. The Systemic Lupus International Collaborating Clinics/ Systemic Damage Index defines systemic lupus erythematosus disease severity and is found to predict prognosis. Read More

    Association Between Weekend and Holiday Admission with Pneumonia and Mortality in a Tertiary Center in Portugal: A Cross-Sectional Study.
    Acta Med Port 2017 May 31;30(5):361-367. Epub 2017 May 31.
    Departamento de Medicina Interna. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
    Introduction: Acute bacterial pneumonia is a common and potentially fatal disease where early recognition and treatment are crucial. Increasing medical literature suggests worse outcomes in patients admitted for medical and surgical conditions during the weekend. Little is known about this effect in patients with acute bacterial pneumonia. Read More

    [Analysis of the Cochrane Review: Pharmacotherapy for Hyperuricemia in Hypertensive Patients. Cochrane Database Syst Rev. 2017;4:CD008652.]
    Acta Med Port 2017 May 31;30(5):356-360. Epub 2017 May 31.
    Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal.
    Arterial hypertension is a public health problem that affects approximately 25% of the world's adult population. The association between hypertension and hyperuricemia has been shown on epidemiological and experimental studies. However, it is unclear whether lowering serum uric acid might lower blood pressure. Read More

    [Genetic Study of Primary Dystonias: Recommendations from the Centro Hospitalar São João Neurogenetics Group].
    Acta Med Port 2017 Apr 28;30(4):340-346. Epub 2017 Apr 28.
    Departamento de Neurociências Clínicas e Saúde Mental. Faculdade de Medicina. Universidade do Porto. Porto. Portugal. Serviço de Neurologia. Centro Hospitalar São João. Porto. Portugal.; Serviço de Neurologia, Departamento de Neurociências Clínicas e Saúde Mental, Faculdade de Medicina da Universidade do Porto.
    The primary dystonias are a particular group of dystonias of presumed genetic origin, with a wide age of onset and variable progression. The diagnosis is, therefore, a challenge and the issue of the genetic investigation presents frequently in clinical practice. In the past few years several gene mutations have been identified as causative of primary dystonias. Read More

    Bilateral Deep Vein Thrombosis Associated with Inferior Vena Cava Agenesis in a Young Patient Manifesting as Low Back Pain.
    Acta Med Port 2017 Apr 28;30(4):333-337. Epub 2017 Apr 28.
    Radiology and Imaging Diagnosis. University Hospital of Santa Maria. Rio Grande do Sul. Brazil.
    Congenital absence of the inferior vena cava is a rare vascular anomaly, and most cases are asymptomatic. Nevertheless, patients with inferior vena cava malformations may have increased risk of deep venous thrombosis. Particularly, cases of bilateral deep venous thrombosis may arise owing to an insufficient collateral venous drainage from the lower limbs. Read More

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