80 results match your criteria Acta medica Lituanica[Journal]


The impact of anti-cyclic citrullinated peptide antibody status on the management of patients with early rheumatoid arthritis: observational study results from Lithuania.

Acta Med Litu 2018 ;25(2):112-123

AbbVie Baltic States, Vilnius, Lithuania.

Background: To provide data on the use of anti-cyclic citrullinated peptide antibody (anti-CCP) and other routinely used clinical parameters and to assess the impact of anti-CCP status on therapeutic decisions, an observational study was conducted in patients with rheumatoid arthritis (RA).

Methods: Sixty-seven adult patients with a recent diagnosis of RA were recruited from four rheumatology centres in Lithuania and were prospectively observed for 12 months. Data collection was based on the review of medical records and routine examination of patients. Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130926PMC
January 2018
19 Reads

A survey of some aspects of birthday celebration.

Acta Med Litu 2018 ;25(2):107-111

Clinic of Psychiatry, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: The tradition of celebrating the day of birth of an individual is thought to have existed since the ancient times. Depending on the culture, religious beliefs, and the geographic location, occasions for ritual performance differ greatly. The aim of this pilot study was to investigate how students in Lithuania evaluate the importance of their birthday. Read More

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http://lmaleidykla.lt/ojs/index.php/actamedicalituanica/arti
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http://dx.doi.org/10.6001/actamedica.v25i2.3764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130922PMC
January 2018
4 Reads

The impact of music on the bioelectrical oscillations of the brain.

Acta Med Litu 2018 ;25(2):101-106

Department of Children's Neurology, Children's Hospital, Affiliate of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.

In this article we conclude the main scientific studies into the changes in the bioelectrical brainwave activity that occur while listening to music. A brainwave spectral analysis, derived from findings of electroencephalograms, is a powerful tool to obtain deep and objective insights into the effects of music on the brain. This capacity is being investigated in various contexts. Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130927PMC
January 2018
26 Reads

Congenital cystic adenomatous malformation: a case report and a literature review.

Acta Med Litu 2018 ;25(2):95-100

Clinic of Obstetrics and Gynaecology, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: A congenital cystic adenomatoid malformation (CCAM) is a foetal pulmonary development abnormality caused by airway dysgenesis that is characterized by cystic or adenomatous lesions in the terminal bronchioles. The size of the mass, the degree of the mediastinal shift, and the presence of hydrops and polyhydramnios can all affect the severity of a case. Treatment can be initiated at early stages by applying prenatal and postnatal methods. Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130925PMC
January 2018
2 Reads

Evaluation of the presence of MMP-2, TIMP-2, BMP2/4, and TGFβ3 in the facial tissue of children with cleft lip and palate.

Acta Med Litu 2018 ;25(2):86-94

Institute of Anatomy and Anthropology, Department of Morphology, Riga Stradiņš University, Riga, Latvia.

Cleft lip and palate (CLP) is the most common defect affecting the face. The treatment consists of surgical reconstruction of the anatomical structures of the cleft. Part of the surgical treatment is reconstruction of the alveolar bone by means of autogenic bone grafting (osteoplasty). Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130923PMC
January 2018
11 Reads

Hospitalisation of late preterm infants due to lower respiratory tract infections in Lithuania, Latvia, and Estonia: incidence, disease severity, and risk factors.

Acta Med Litu 2018 ;25(2):76-85

AbbVie Baltic States, Vilnius, Lithuania.

Background: By two years of age, almost all children experience at least one episode of respiratory syncytial virus (RSV) infection, the most common viral cause of hospitalisation due to lower respiratory tract infection (LRTI). We present data on LRTI hospitalisations (with a special focus on RSV), the course of illness, and LRTI hospitalisation risk factors in Lithuania, Latvia, and Estonia.

Materials And Methods: The analysed data were part of a large multinational study conducted in 23 countries (PONI). Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130930PMC
January 2018
6 Reads

Diagnosis, treatment, and outcomes of encapsulated papillary carcinoma: a single institution experience.

Acta Med Litu 2018 ;25(2):66-75

National Centre of Pathology, Vilnius, Lithuania.

Background: Encapsulated papillary carcinoma (EPC) is a rare entity of breast cancer accounting for approximately 1-2% of all breast tumours. There are no evidence-based guidelines for the treatment of EPC.

Materials And Methods: From the database of the National Centre of Pathology (NCP), we obtained pathology reports of 19 patients with histologically confirmed EPC, who were treated at the National Cancer Institute (NCI) in Vilnius, Lithuania, between July 2009 and July 2015. Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130924PMC
January 2018

Placenta percreta complicated by uterine rupture and thrombotic microangiopathy.

Acta Med Litu 2018 ;25(2):61-65

Department of Obstetrics and Gynaecology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Uterine rupture at the site of a previous caesarean scar with abnormal placental penetration through the uterus wall with bladder invasion is a rare and serious pregnancy complication. Our aim was to report a case of uterine rupture with placenta percreta complicated by thrombotic microangiopathy.

Materials And Methods: We did a literature review and analysed medical documentation retrospectively. Read More

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http://dx.doi.org/10.6001/actamedica.v25i2.3758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130928PMC
January 2018
4 Reads

Effectiveness of treatment of occipital neuralgia using the nerve block technique: a prospective analysis of 44 patients.

Acta Med Litu 2018 ;25(2):53-60

Department of Neurosurgery, State Vilnius University Hospital, Vilnius, Lithuania.

Background: There is a great deal of tools for treatment of occipital neuralgia but currently we are lacking a complete consensus among practitioners regarding the optimal approach to this debilitating condition. Occipital nerve block (ONB) is known as one of the management options but there is lack of scientific literature exploring its effectiveness.

Materials And Methods: The prospective study was undertaken between March 2014 and February 2018 at the State Vilnius University Hospital. Read More

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http://lmaleidykla.lt/ojs/index.php/actamedicalituanica/arti
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http://dx.doi.org/10.6001/actamedica.v25i2.3757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130929PMC
January 2018
4 Reads

Risk factors of developing the hungry bone syndrome after parathyroidectomy for primary hyperparathyroidism.

Acta Med Litu 2018 ;25(1):45-51

Faculty of Medicine Vilnius University, Vilnius, Lithuania.

Background: Around 13% of patients undergoing parathyroidectomy for primary hyperparathyroidism (PHPT) postoperatively develop a condition known as the hungry bone syndrome (HBS). Although the condition is quite prevalent, the research in this field is very limited. The aim of our study was to determine possible risk factors of developing HBS after parathyroidectomy for PHPT. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008000PMC
January 2018
5 Reads

Recommendations and a guideline for referral of infantile haemangioma to tertiary centres.

Acta Med Litu 2018 ;25(1):38-44

Children's Hospital, Affiliate of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.

Background: Infantile haemangioma is the most common childhood vascular tumour, which causes great anxiety to parents and treating first-line physicians due to its proliferative nature. It accounts for a large percentage of a tertiary centre consultations, thus delaying consultation time for patients in need of immediate care.

Materials And Methods: Review of literature and experience of treatment and observation of infantile haemangiomas in a tertiary centre of paediatric surgery. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008002PMC
January 2018

Malignant mixed epithelial and stromal tumour of the kidney: a case report and a literature review.

Acta Med Litu 2018 ;25(1):31-37

National Cancer Institute, Vilnius, Lithuania.

Introduction: Mixed epithelial and stromal tumour of the kidney (MEST) is a rare and distinctive neoplasm accounting for 0.2% of all renal cancers. Most of these tumours behave in a benign fashion but 13 cases with malignant transformation have already been reported. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008004PMC
January 2018
18 Reads

Primary gastric Burkitt lymphoma-induced anaemia: a case report and a literature review.

Acta Med Litu 2018 ;25(1):23-30

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Primary tumours of the gastrointestinal tract are very uncommon in children. They can present with anaemia caused by gastrointestinal acute or chronic bleeding. One of the most common gastrointestinal tumours is Burkitt lymphoma. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007999PMC
January 2018

Evaluation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for the patients in the intensive care unit.

Acta Med Litu 2018 ;25(1):14-22

Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Introduction: Delirium not only compromises patient care, but is also associated with poorer outcomes: increased duration of mechanical ventilation, higher mortality, and greater long-term cognitive dysfunction. The PRE-DELIRIC model is a tool used to calculate the risk of the development of delirium. The classification of the patients into groups by risk allows efficient initiation of preventive measures. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008005PMC
January 2018
18 Reads

Novel human genome variants associated with alcohol use disorders identified in a Lithuanian cohort.

Acta Med Litu 2018 ;25(1):7-13

Department of Human and Medical Genetics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Alcohol use disorder (AUD) is a chronic relapsing brain disease characterized by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using (1). Abusive alcohol consumption directly affects a person's physical and psychological health and social life. The World Health Organization has shown that Lithuania is a leading country in pure alcohol consumption in the world (2). Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008003PMC
January 2018
10 Reads

A rare case of REM sleep-related bradyarrhythmia syndrome with concomitant severe hypertension: a case report and a review of literature.

Acta Med Litu 2018 ;25(1):1-6

Clinic of Heart and Vascular Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Introduction: Rapid eye movement (REM) sleep-related bradyarrhythmia syndrome is characterized by pathological asystoles during the REM sleep phase. It is a rare rhythm disorder, being reported only few times in the literature. Due to non-specific symptoms, REM sleep-related bradyarrhythmia might be often underdiagnosed. Read More

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http://dx.doi.org/10.6001/actamedica.v25i1.3697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008001PMC
January 2018
24 Reads

Relationships between pulmonary function test parameters and quantitative computed tomography measurements of emphysema in subjects with chronic obstructive pulmonary disease.

Acta Med Litu 2017 ;24(4):209-218

Department of Mathematical Statistics of Vilnius Gediminas Technical University, Vilnius, Lithuania.

Objective: CT is able to precisely define the pathological process in COPD. There are a number of previous articles discussing the distribution of emphysema and its connection with pulmonary function tests. However, the results obtained by the researchers are not identical. Read More

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http://dx.doi.org/10.6001/actamedica.v24i4.3616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818256PMC
January 2017
1 Read

Survival of children treated for Ewing sarcoma in Lithuania: a single centre experience.

Acta Med Litu 2017 ;24(4):199-208

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Introduction: Ewing sarcoma (ES) is a rare and aggressive malignant neoplasm that mostly affects children and adolescents. Recent studies reported a gap of 20% in childhood cancer survival rates between the Northern/Western and the Eastern European countries. We aimed to analyse the survival of patients treated for ES at our institution, to evaluate its correspondence to current survival rates in the expert centres, and to assess changes in treatment outcomes over time. Read More

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http://dx.doi.org/10.6001/actamedica.v24i4.3615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818255PMC
January 2017
6 Reads

Respiratory syncytial virus infection in a selected sample of infants hospitalized for lower respiratory tract infection in Lithuania and Estonia.

Acta Med Litu 2017 ;24(4):191-198

Clinic of Children Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: The study presents data on a sample of children under one year of age hospitalized with lower respiratory tract infections (LRTIs) in Lithuania and Estonia.

Subjects And Methods: This large, retrospective, cross-sectional, observational epidemiologic survey was conducted in 12 countries in Central and Eastern Europe. Eligible subjects were under one year of age, hospitalized for LRTIs, for whom RDT (Rapid Diagnostic Test) was performed. Read More

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http://dx.doi.org/10.6001/actamedica.v24i4.3614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818254PMC
January 2017
5 Reads

The role of and gene polymorphisms in pituitary adenoma.

Acta Med Litu 2017 ;24(4):177-190

Department of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: The pathogenesis of pituitary adenoma (PA) is complex and poorly understood. It is thought that PA has a multifactorial aetiology; genetic factors also have an impact on PA development. Since and genes play an important role in tumour growth, differentiation and progression, we decided to determine if the frequency of the genotypes of and polymorphisms influence the development of PA. Read More

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http://dx.doi.org/10.6001/actamedica.v24i4.3613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818253PMC
January 2017
3 Reads

Evaluation of quality of life after paediatric cochlear implantation.

Acta Med Litu 2018 ;25(3):173-184

Clinic of Ear, Nose, Throat and Eye Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Cochlear implantation (CI) is the main treatment method for deaf children. CI influences not only communication, but also psychosocial outcomes in children with severe to profound hearing loss. Focusing on issues specific to CI (e. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392602PMC
January 2018
1 Read

Acute kidney injury in an extremely low birth weight infant with nephrolithiasis: a case report.

Acta Med Litu 2018 ;25(3):166-172

Neonatology Centre, Children's Hospital, Affiliate of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.

Acute kidney injury is associated with mortality of very low birth weight infants and reduces their survival regardless of other factors. The kidneys in the extremely preterm infants are very immature and susceptible to environmental factors. Clinical conditions and medications are risk factors for acute kidney injury in these patients. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392603PMC
January 2018
2 Reads

Survival and time interval from surgery to the start of chemotherapy for patients with stage II and III colon cancer.

Acta Med Litu 2018 ;25(3):161-165

Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Vilnius, Lithuania.

Background: Usually adjuvant chemotherapy is started within 12 weeks of surgery, but the evidence on the commencing time is lacking. Our aim was to investigate the association of initiating post-surgery treatment within six weeks six to ten weeks more than ten weeks with survival.

Methods: We analysed the association of treatment and its timing with survival among patients who were diagnosed and underwent surgery for stage II or III colon cancer from 2012 to 2013 at the National Cancer Institute, Lithuania. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392599PMC
January 2018
3 Reads

Trends in the incidence and mortality of kidney cancer in Lithuania from 1993 to 2012.

Acta Med Litu 2018 ;25(3):151-160

National Cancer Institute, Vilnius, Lithuania.

Background: The aim of this paper is to analyse trends of kidney cancer incidence and mortality in Lithuania during the period of 1993 to 2012 using joinpoint regression models with special attention to changes in the distribution of stages.

Materials And Methods: The study was based on all cases of kidney cancer reported to the Lithuanian Cancer Registry between 1993 and 2012. Age group-specific rates and standardized rates were calculated for each sex, using the direct method (world standard population). Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392605PMC
January 2018

Valvular heart disease during pregnancy: a clinical case and a literature review.

Acta Med Litu 2018 ;25(3):140-150

Faculty of Medicine, ilnius University Vilnius, Lithuania.

Background: As a result of improved diagnostic and reparative techniques, congenital heart diseases are becoming a significant problem for women of childbearing age. Nowadays, more pregnant women in the West are being diagnosed with an acquired heart disease because of the tendency to delay childbearing and increasing age-related risk of developing complications of hypertension, diabetes, obesity and other diseases. According to the Lithuanian Health Information Centre, the incidence of cardiovascular diseases in pregnancy is decreasing in Lithuania, from 1. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392604PMC
January 2018
7 Reads

Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians.

Acta Med Litu 2018 ;25(3):132-139

Clinic of Cardiac and Vascular Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: The data on long-term outcomes for elderly patients with coronary artery disease who undergo invasive treatment is limited. This study aimed to assess long-term outcomes and risk factors for patients over 80 years of age who underwent revascularisation.

Methods: This single-centre retrospective study included ≥80-year-old patients who underwent coronary angiography between 2012 and 2014. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392600PMC
January 2018
2 Reads

Is the Trendelenburg position the only way to better visualize internal jugular veins?

Acta Med Litu 2018 ;25(3):125-131

Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: A larger cross-sectional area (CSA) of the internal jugular vein (IJV) makes catheterization easier and the Trendelenburg position is used to achieve this. Unfortunately, it is not comfortable for conscious patients. The aim was to evaluate the impact of alternative manoeuvres on the enlargement of the CSA of the IJV and to compare these manoeuvres with the Trendelenburg position. Read More

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http://dx.doi.org/10.6001/actamedica.v25i3.3859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392601PMC
January 2018

Hybrid transanal and total mesorectal excision after transanal endoscopic microsurgery for unfavourable early rectal cancer: a report of two cases.

Acta Med Litu 2017 ;24(3):188-192

General Surgery Department, Aintree University Hospital NHS Foundation Trust, University of Liverpool, Liverpool, United Kingdom.

Completion total mesorectal excision (TME) is a rare but complex procedure after transanal endoscopic microsurgery for early rectal cancer with unfavourable final histology. Two cases are reported when completion TME was performed after upfront transanal partial mesorectal dissection. Intact non-perforated TME specimens with negative and adequate distal and circumferential margins were created. Read More

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http://dx.doi.org/10.6001/actamedica.v24i3.3553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709058PMC
January 2017
17 Reads

Clinical aspects and antenatal diagnosis of invasive placenta: a review of ten-years' experience of a multi-profile hospital in Lithuania.

Acta Med Litu 2017 ;24(3):176-187

Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.

Background: Invasive placenta is a rare obstetrical pathology that is life-threatening to mother and child. It is important to diagnose this pathology as early as possible and to plan further optimal care of patients in order to minimize life-threatening complications. The aim of this study was to analyze the frequency of cases of invasive placenta, the peculiarities of their clinical manifestation in women who gave birth from 2006 to 2015, to evaluate diagnostic and treatment options of this pathology, and to review their changes when the level of services provided by the institution changes. Read More

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http://dx.doi.org/10.6001/actamedica.v24i3.3552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709057PMC
January 2017
8 Reads

Evaluation of the relationship between the occlusion parameters and symptoms of the temporomandibular joint disorder.

Acta Med Litu 2017 ;24(3):167-175

Clinical Department of Dental and Maxillary Orthopaedics, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: The aetiology of temporomandibular joint disorders (TMD) is multifactorial, whereas occlusal disharmony is one of the predisposing factors. Researchers still discuss the relation between occlusion and TMD.

Objective: The study aims to investigate the relation between static occlusal parameters and TMD clinical symptoms using T-Scan II analysis system. Read More

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http://www.lmaleidykla.lt/ojs/index.php/actamedicalituanica/
Publisher Site
http://dx.doi.org/10.6001/actamedica.v24i3.3551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709056PMC
January 2017
6 Reads

Recurrent pericarditis: a case report and literature review.

Acta Med Litu 2017 ;24(3):159-166

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Recurrence affects about 30% (20% to 50%) of patients within 18 months after the initial episode of acute pericarditis resulting in subsequent rehospitalizations. Bearing in mind high treatment costs of patients admitted to hospital with acute and recurrent pericarditis, there is a need to optimize the treatment of both of these conditions.

Materials And Methods: We present a case of recurrent pericarditis. Read More

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http://www.lmaleidykla.lt/ojs/index.php/actamedicalituanica/
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http://dx.doi.org/10.6001/actamedica.v24i3.3550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709055PMC
January 2017
4 Reads

Severity of hyperoxia as a risk factor in patients undergoing on-pump cardiac surgery.

Acta Med Litu 2017 ;24(3):153-158

Clinic of Anaesthesiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: Hyperoxia has long been perceived as a desirable or at least an inevitable part of cardiopulmonary bypass. Recent evidence suggest that it might have multiple detrimental effects on patient homeostasis. The aim of the study was to identify the determinants of supra-physiological values of partial oxygen pressure during on-pump cardiac surgery and to assess the impact of hyperoxia on clinical outcomes. Read More

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http://dx.doi.org/10.6001/actamedica.v24i3.3549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709054PMC
January 2017
4 Reads

Investigation of markers of allergic sensitization and viral infections in children with allergy and asthma.

Acta Med Litu 2017 ;24(3):145-152

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Allergic diseases are the most prevalent chronic diseases in the developed countries. It is believed that early allergic sensitization and respiratory viral infections play an important role in the development of allergic diseases and asthma.

Methods: The current study investigated the correlation between asthma, allergy, and various markers - allergen-specific IgE, IgG4 and IgA, ECP, IgM, and IgG antibodies against respiratory viruses hRSV and hPIV1-4 - in blood serum samples from 80 children (mean age 5. Read More

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http://dx.doi.org/10.6001/actamedica.v24i3.3548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709053PMC
January 2017
2 Reads

Cell-free DNA in non-small cell lung cancer.

Acta Med Litu 2017 ;24(2):138-144

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Lung cancer is the leading cause of cancer-associated deaths worldwide. Surgery is the standard treatment for early-stage non-small cell lung cancer (NSCLC). Advances in the knowledge of the biology of non-small cell lung cancer have revealed molecular information used for systemic cancer therapy targeting metastatic disease, with an important impact on patients' overall survival (OS) and quality of life. Read More

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http://lmaleidykla.lt/ojs/index.php/actamedicalituanica/arti
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http://dx.doi.org/10.6001/actamedica.v24i2.3495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566953PMC
January 2017
10 Reads

Results of neuroblastoma treatment in Lithuania: a single centre experience.

Acta Med Litu 2017 ;24(2):128-137

Medical Faculty, Vilnius University, Vilnius, Lithuania.

Background: Neuroblastoma (NB) is the most common extracranial solid tumour in children. This is a very rare disease with heterogeneous biology varying from complete spontaneous regression to a highly aggressive tumour responsible for 15% of malignancy-related death in early childhood. Analyses of survival rates in Europe have shown a considerable difference between Northern/Western and Eastern European countries. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566952PMC
January 2017
9 Reads

Anaesthetic challenges in cancer patients: current therapies and pain management.

Acta Med Litu 2017 ;24(2):121-127

Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

The Objective: The aim is to present the major effects of cancer treatment (chemotherapy, radiotherapy, surgery) that the anaesthesiologist should consider preoperatively, and to review techniques of the analgesic management of the disease.

Materials And Methods: To summarize the major challenges that cancer patients present for the anaesthesiologists, a literature review was conducted. Articles presenting evidence or reviewing the possible effects of anaesthetics on cancer cells were also included. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566951PMC
January 2017
1 Read

Sepsis epidemiology and outcome in the paediatric intensive care unit of Vilnius University Children's Hospital.

Acta Med Litu 2017 ;24(2):113-120

Medical Faculty, Vilnius University, Vilnius, Lithuania.

Research was carried out at the paediatric intensive care unit (paediatric ICU) of the Children's Hospital, affiliate of Vilnius University Hospital Santariškių klinikos.

Background: Being the most common cause of children's death, sepsis is a challenge for most physicians. In order to improve the outcomes, it is important to know the aetiology and peculiarities of sepsis in a particular region and hospital. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566950PMC
January 2017
2 Reads

Clinical characteristics and long-term survival differences of the ANCA-associated vasculitis group: a cross-sectional study of 27 patients.

Acta Med Litu 2017 ;24(2):107-112

Centre of Rheumatology, Vilnius University Hospital Santaros klinikos, Vilnius, Lithuania.

Objective: The goal of this study was to describe long-term patient survival and possible prognostic factors of a group of patients diagnosed with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) hospitalized at the tertiary Rheumatology Centre in Vilnius.

Material And Methods: A cross-sectional study of 27 patients hospitalized at the Rheumatology Centre of Santaros klinikos of Vilnius University Hospital from 1 January 2001 to 31 December 2015 with diagnoses of GPA and MPA were carried out. Data on demographics, clinical characteristics, laboratory data, and the Birmingham Vasculitis Activity Score were collected. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566949PMC
January 2017
17 Reads

Complications of orbital endoimplantation in the Eye Clinic of the Lithuanian University of Health Sciences.

Acta Med Litu 2017 ;24(2):101-106

Eye Clinic, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

The aim of the study was to analyse the rate of complications of orbital endoimplantation in patients operated from 2002 to 2014 at the Eye Clinic of the Lithuanian University of Health Sciences and to compare it with the results in the literature. Enucleation must be performed very carefully in order to prevent any additional trauma, infection, deformation, and to create an optimal conjunctival socket. However, complications occur despite efforts and qualified surgeons. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566948PMC
January 2017
6 Reads

Changes in macular thickness after trabeculectomy with or without adjunctive 5-fluorouracil.

Acta Med Litu 2017 ;24(2):93-100

Singapore Eye Research Institute, Singapore.

Conflict Of Interest: None of the authors have any conflict of interest to declare, financial or otherwise. No financial or other support was received for the study.

Background: The aim of the study was to assess changes in macular thickness after trabeculectomy in respect to the use of 5-fluorouracil (5-FU) as well as to analyse possible associations between the postoperative changes in macular thickness and intraocular pressure (IOP). Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566947PMC
January 2017
5 Reads

Refractive errors characteristic of the patients at the Children's Ophthalmology Outpatient Department of Kauno klinikos Hospital (Lithuanian University of Health Sciences) from 1 January 2012 to 31 December 2012.

Acta Med Litu 2017 ;24(2):83-92

Department of Ophthalmology, Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: The purpose of our study was to assess the distribution and patterns of refractive errors in children for the proper planning of paediatric eye care at the centre.

Material And Methods: The study was conducted in the hospital of the Lithuanian University of Health Sciences in Kaunas, from 1 January 2012 to 31 December 2012. During this period, a total of 11,406 children, aged 0-18 years, were evaluated at the outpatient department of paediatric ophthalmology, Kauno klinikos, the Lithuanian University of Health Sciences. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566946PMC
January 2017

Associations between rs10509681 and rs11572080 gene polymorphisms and age-related macular degeneration.

Acta Med Litu 2017 ;24(2):75-82

Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in industrialized countries. Early symptoms of AMD include drusen and changes in retinal pigment epithelium. However, the etiology of AMD and drusen formation is not fully understood. Read More

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http://dx.doi.org/10.6001/actamedica.v24i2.3487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566945PMC
January 2017
6 Reads

Individual Meaning-Centered Psychotherapy for palliative cancer patients in Lithuania. A case report.

Acta Med Litu 2017 ;24(1):67-73

National Cancer Institute, Vilnius, Lithuania.

Patients with oncological diseases, especially palliative care patients, suffer from physical and psychological difficulties. The quality of life of such patients is bad, they do not have purpose to live and they feel anxiety and distress. In 1959 Victor Frankl wrote the book in which he stated that the driving force of human life lay in the ability to discern the meaning of faith and spirituality. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467964PMC
January 2017
1 Read

Hemofagocitinė limfohistiocitozė: literatūros apžvalga.

Acta Med Litu 2017 ;24(1):51-66

Vilniaus universiteto Medicinos fakulteto Vaikų ligų klinika.

Hemophagocytic Lymphohistiocytosis A Literature Review: Hemophagocytic lymphohistiocytosis is an immune dysregulatory syndrome that is associated with alteration in the immune response activation and inhibition balance. There are two basic forms of the syndrome: primary (genetic or familial) determined by genes mutations involved in immune cell interactions, and secondary or sporadic developing as a result of an infectious process. The exact genetic background of the secondary form is still unknown. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467963PMC
January 2017
3 Reads

The role of different PI-RADS versions in prostate multiparametric magnetic resonance tomography assessment.

Acta Med Litu 2017 ;24(1):44-50

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

. Standardised Prostate Imaging Reporting and Data System (PI-RADS) guidelines for the assessment of prostate alterations were designed for the assessment of prostate pathology. Published by the ESUR in 2012, PI-RADS v1 was based on the total score of different MRI sequences with subsequent calculation. Read More

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http://www.lmaleidykla.lt/ojs/index.php/actamedicalituanica/
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http://dx.doi.org/10.6001/actamedica.v24i1.3462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467962PMC
January 2017
6 Reads

NOTCH signalinio kelio ir ginekologinių piktybinių navikų sąsaja.

Acta Med Litu 2017 ;24(1):35-43

Nacionalinis vėžio institutas, Mokslinių tyrimų centras.

The Association Between The Notch Signaling Pathway And Gynaecological Malignancies: The body's cell behaviour is controlled by various signalling pathways, one of which is NOTCH. It has been found that a partial loss of the NOTCH function or abnormal strengthening of NOTCH signalling are related to various human diseases and developmental disorders. PubMed was the main source of information for this paper. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467961PMC
January 2017
5 Reads

Analysis of prognostic factors for melanoma patients.

Acta Med Litu 2017 ;24(1):25-34

Faculty of Medicine, Vilnius University.

Melanoma is the most dangerous form of skin cancer. Morbidity from melanoma is increasing every year. Previous studies have revealed that there are some demographic and clinical factors having effect on melanoma survival prognosis. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467960PMC
January 2017
6 Reads

Laparoscopic colorectal surgery for colorectal polyps: experience of ten years.

Acta Med Litu 2017 ;24(1):18-24

Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Vilnius, Lithuania.

Laparoscopy or its combination with endoscopy is the next step for "difficult" polyps. The purpose of the paper was to review the outcomes of the laparoscopic approach to the management of "difficult" colorectal polyps. From 2006 to 2016, 58 patients who underwent laparoscopic treatment for "difficult" polyps that could not be treated by endoscopy at the National Cancer Institute, Lithuania, were included. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467959PMC
January 2017
6 Reads

Testicular cancer in two brothers of a quadruplet: a case report and a review of literature.

Acta Med Litu 2017 ;24(1):12-17

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467958PMC
January 2017
5 Reads

The most common technologies and tools for functional genome analysis.

Acta Med Litu 2017 ;24(1):1-11

Department of Human and Medical Genetics, Faculty of Medicine, Vilnius University Vilnius, Lithuania.

Since the sequence of the human genome is complete, the main issue is how to understand the information written in the DNA sequence. Despite numerous genome-wide studies that have already been performed, the challenge to determine the function of genes, gene products, and also their interaction is still open. As changes in the human genome are highly likely to cause pathological conditions, functional analysis is vitally important for human health. Read More

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http://dx.doi.org/10.6001/actamedica.v24i1.3457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467957PMC
January 2017
19 Reads