905 results match your criteria Acta medica Hradec Kralove[Journal]


Penile Degloving and Dorsal Dartos Flap Rotation Surgery in the Management of Severe Isolated Penile Torsion in a 6-Year-Old Boy.

Acta Medica (Hradec Kralove) 2020 ;63(1):52-54

College of Medicine, QU Health, Qatar University, Doha, Qatar.

Penile torsion is a rare congenital anomaly that is usually characterized by a counterclockwise rotation of the penile shaft or glans. Although several surgical techniques for its correction have been proposed, the consensus of choosing the most efficient technique remains controversial. Herein, we report our operational approach that successfully corrected a severe (>90 degrees) isolated penile torsion in the form of penile degloving and dorsal dartos flap rotation surgery. Read More

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http://dx.doi.org/10.14712/18059694.2020.16DOI Listing
January 2020

An Alternative Treatment for Vaginal Cuff Wart: a Case Report.

Acta Medica (Hradec Kralove) 2020 ;63(1):49-51

Department of Gynecologic Oncology, Metaxa Memorial Cancer Hospital, Piraeus, Greece.

Human papillomavirus (HPV) has been directly related to acuminate warts and cervical cancer, the second most common neoplasia among women. Given the lack of treatment against the virus itself, many medications have been utilised, mainly aiming in modifying the host's immunological response. We present the case of a 54 years old postmenopausal patient with a history of vaginal cuff wart and HPV persistence that we managed in our clinic for 6 months with a mix of curcumin, aloe vera, amla and other natural ingredients. Read More

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http://dx.doi.org/10.14712/18059694.2020.15DOI Listing
January 2020

Interdisciplinary Management of Visceral Artery Aneurysms and Visceral Artery Pseudoaneurysms.

Acta Medica (Hradec Kralove) 2020 ;63(1):43-48

Clinic of Vascular Surgery, East Slovak Institute of Cardiovascular Diseases, Faculty of Medicine, Pavol Jozef Šafárik University, Košice, Slovak Republic.

The paper presents the results of treating 14 patients, namely eight patients with visceral artery aneurysms and six patients with visceral artery pseudoaneurysms. In 64.3% of the patients, the initial diagnosis was made based on the ultrasound examination. Read More

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http://dx.doi.org/10.14712/18059694.2020.14DOI Listing
January 2020

Association of PAI-1 rs1799889 Polymorphism with Susceptibility to Ischemic Stroke: a Huge Meta-Analysis based on 44 Studies.

Acta Medica (Hradec Kralove) 2020 ;63(1):31-42

Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Background: the PAI-1 rs1799889 polymorphism has been reported to be associated with susceptibility to ischemic stroke. However, the results of previous studies have been inconsistent or controversial. Hence, we performed a systematic review and meta-analysis to evaluate the association of PAI-1 rs1799889 polymorphism with ischemic stroke risk. Read More

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http://dx.doi.org/10.14712/18059694.2020.13DOI Listing
January 2020

Comparison of Subthreshold 532 nm Diode Micropulse Laser with Conventional Laser Photocoagulation in the Treatment of Non-Centre Involved Clinically Significant Diabetic Macular Edema.

Acta Medica (Hradec Kralove) 2020 ;63(1):25-30

Department of Ophthalmology, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.

Background: The aim of the study was to investigate the effect of the 532 nm (green) diode subthreshold micropulse laser (SML) in the treatment of non-centre involved clinically significant macular edema (CSME) in comparison to the conventional laser photocoagulation (CLP).

Methods: A total of 60 eyes of patients diagnosed with non-centre involved CSME were randomly divided into two groups. SML photocoagulation was performed in the first group (G1), while CLP in the second one (G2). Read More

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http://dx.doi.org/10.14712/18059694.2020.12DOI Listing
January 2020

Experimental Evaluation of the Impact of Gadolinium Orthovanadate GdVO4:Eu3+ Nanoparticles on the Carrageenan-Induced Intestinal Inflammation.

Acta Medica (Hradec Kralove) 2020 ;63(1):18-24

Department of Biochemistry, Kharkiv National Medical University, Kharkiv, Ukraine.

Aim: To evaluate the effects of orally administered gadolinium orthovanadate GdVO4:Eu3+ nanoparticles (VNPs) on the course of chronic carrageenan-induced intestinal inflammation.

Methods: Samples of small intestinal tissue were collected from four groups of rats (intact, after administration of VNPs, with carrageenaninduced intestinal inflammation, with carrageenan-induced intestinal inflammation orally exposed to VNPs) to assess the intestinal morphology and HSP90α expression. Levels of seromucoid, C-reactive protein, TNF-α, IL-1β and IL-10 were determined in blood serum. Read More

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http://dx.doi.org/10.14712/18059694.2020.11DOI Listing
January 2020

Epidemiology of Melanoma in the Czech Republic in East Bohemia in the Period 2002-2017 and the Effect of the Annual Sunshine Exposure.

Acta Medica (Hradec Kralove) 2020 ;63(1):10-17

Department of Dermatology and Venereology Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Aim: The evaluation of the trend in the occurrence of melanoma nodulare, melanoma superficiale, lentigo maligna and melanoma in situ in the period of 2002-2017 in East Bohemia region in the Czech Republic. We examine if the annual numbers of hours of sunshine could affect the number of patients with melanoma.

Method: In the peridod of 2002-2017, altogether 2230 patients with new diagnosis of melanoma were examined. Read More

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http://dx.doi.org/10.14712/18059694.2020.10DOI Listing
January 2020

Melanoma Incidence in Czech Republic, the Relation between Histology, Body Site of Melanoma, and Duration of Lesions.

Acta Medica (Hradec Kralove) 2020 ;63(1):1-9

Department of Dermatology and Venereology Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Aim: To evaluate the occurrence of melanoma in the period 1996-2017 in East Bohemia region in the Czech Republic.

Method: We studied the incidence of melanoma and the age of diagnosis (adjusted calculation) and the parameters such as histology, body site of lesions, the length of the duration of lesions in 2810 patients.

Results And Conclusion: No change in the occurrence of melanoma and in age of melanoma during this period was found. Read More

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http://dx.doi.org/10.14712/18059694.2020.9DOI Listing
January 2020

Ultrashort ssDNA in Retinoblastoma Patients Blood Plasma Detected by a Novel High Resolution HPLC Technique: a Preliminary Report.

Acta Medica (Hradec Kralove) 2019 ;62(4):170-173

N.I. Pirogov Russian National Research Medical University, Russian Federal Ministry of Health, Ostrovityanov St., 1, Moscow 117997, Russia.

A significant population of ultrashort (50-150n) single-stranded DNA fragments were found in exosome-free blood plasma of retinoblastoma patients (6.84 ng mL-1), but not in plasma of healthy donors. An original high resolution HPLC technique has been proposed to reveal and characterize this peculiarity. Read More

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http://dx.doi.org/10.14712/18059694.2020.8DOI Listing

Drug-induced Hemolysis in G6PD Deficiency: an Unusual Presentation of a Common Clinical Condition.

Acta Medica (Hradec Kralove) 2019 ;62(4):166-169

Department of Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Glucose-6-phosphate dehydrogenase (G6PD) deficiency can present a diagnostic dilemma owing to the varying degrees of disease severity and the wide range of precipitating factors. Here, we report a case of a 56-year-old man who presented with signs and symptoms of heart failure and, during the course of treatment, developed intravascular hemolysis. On investigation, he was found to be G6PD deficient. Read More

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http://dx.doi.org/10.14712/18059694.2020.7DOI Listing

Mucopolysaccharidosis Type I in Children, a Forgotten Diagnosis Responsible for Undiagnosed Musculoskeletal Complaints: Report of Two Cases.

Acta Medica (Hradec Kralove) 2019 ;62(4):161-165

Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.

Mucopolysaccharidoses (MPS) are a subgroup of lysosomal storage disorders. The underlying mechanism of MPS disorders are deficiency in specific enzymes which leads to accumulation of partially degraded glycosaminoglycans (GAGs) in various tissues. A wide variety of manifestations are reported but musculoskeletal complaints are common among them. Read More

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http://dx.doi.org/10.14712/18059694.2020.6DOI Listing

Primary Hyperparathyroidism Manifesting with Severe Hypercalcemia in a Nonagenarian Man: Pitfall of Common Imaging Techniques, Localization by 18F-Choline Positron Emission Tomography/Computed Tomography and Successful Management with Calcimimetics.

Acta Medica (Hradec Kralove) 2019 ;62(4):156-160

Nuclear Medicine, Galliera Hospital, Genoa, Italy.

A nonagenarian hypertensive man with chronic kidney disease (CKD) was admitted to the emergency department for gastrointestinal symptoms and worsening symptoms of depression. Severe hypercalcemia (15.3 mg/dL) was found and he was hospitalized. Read More

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http://dx.doi.org/10.14712/18059694.2020.5DOI Listing

Genotype C/C 13910 of the Lactase Gene as a Risk Factor for the Formation of Insulin-Resistant Obesity in Children.

Acta Medica (Hradec Kralove) 2019 ;62(4):150-155

Department of Pediatrics and Medical Genetics, State Institution "Dnepropetrovsk Medical Academy of the Ministry of Health of Ukraine", Dnipro, Ukraine.

Introduction: To reduce the risk of insulin resistance in obesity in children with lactase gene genotypes, we studied the factors that stimulate the chronic inflammatory process.

Material And Methods: 109 children 6-18 years of age were investigated. The main group (n = 56) was presented by children with signs of insulin-resistant obesity according to the criteria of the European Society of Endocrinology and the Pediatric Endocrine Society. Read More

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http://dx.doi.org/10.14712/18059694.2020.4DOI Listing

Robotic Management of Endometriosis: Discussion of Use, Criteria and Advantages: a Review of the Literature.

Acta Medica (Hradec Kralove) 2019 ;62(4):147-149

Department of Obstetrics and Gynecology, General Hospital "Agia Olga", Athens, Greece.

Endometriosis is a very common benign condition affecting fertility and quality of life. Different methods, either definitive or fertility sparing are used for its management by using open, laparoscopic, and robotic techniques. This is a literature review presenting the role and the advantages of robotic surgery in endometriosis. Read More

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http://dx.doi.org/10.14712/18059694.2020.3DOI Listing

Association of IL-6 -174 G>C Polymorphism with Susceptibility to Colorectal Cancer and Gastric Cancer: a Systematic Review and Meta-Analysis.

Acta Medica (Hradec Kralove) 2019 ;62(4):137-146

Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Background: The -174G>C (rs1800795) polymorphism at interleukin 6 (IL-6) gene has been reported to be related with the occurrence of colorectal (CRC) and gastric (GC) cancers. However, the results had been conflicting and controversial. In order to give a comprehensive and precise result, we summarized available data to analyze the association of this polymorphism with CRC and GC risk. Read More

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http://dx.doi.org/10.14712/18059694.2020.2DOI Listing

Pancreatic Adenocarcinoma: Epidemiology, Role of EUS in Diagnosis, Role of ERCP, Endoscopic Palliation.

Acta Medica (Hradec Kralove) 2019 ;62(4):131-136

2nd Department of Internal Medicine - Gastroenterology, Charles University, Faculty of Medicine in Hradec Králové, University Hospital, Hradec Králové, Czech Republic.

Pancreatic cancer is the seventh leading cause of cancer deaths worldwide and is associated with a poor survival rate. The vast majority of pancreatic cancers are inoperable at the time of diagnosis. In the absence of metastatic disease, operability depends on the extent of local disease; in particular, the presence or absence of vascular and lymph node involvement. Read More

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http://dx.doi.org/10.14712/18059694.2020.1DOI Listing

Myelin Oligodendrocyte Glycoprotein Antibody Associated Transverse Myelitis.

Acta Medica (Hradec Kralove) 2019 ;62(3):123-126

Department of Neurology, Pardubice Regional Hospital, Czech Republic.

Antibodies against myelin oligodendrocyte glycoprotein cause inflammatory lesions of central myelin - in optic nerves, of the brainstem, and spinal cord. There are characteristic changes of CNS white matter, protein-cytological association in cerebrospinal fluid, MOG IgG antibodies, a very important differential diagnosis and a relatively mild course. Read More

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http://dx.doi.org/10.14712/18059694.2019.136DOI Listing

Fusiform Cervical Mass in a 6-Year Old Boy; Do not Forget the Thymic Cyst.

Acta Medica (Hradec Kralove) 2019 ;62(3):117-122

First Department of Internal Medicine, General Hospital "Hippokration", Thessaloniki, Greece.

Cervical thymic cyst is a rare clinical entity, with approximately one hundred cases reported in the literature so far. The purpose of this case report is to highlight some certain features, along with an extensive research of the relevant literature. A 6-year-old boy was admitted to the Otorhinolaryngology Department due to the presence of a left-sided, painless, latero-cervical swelling, first observed by his parents 2 weeks ago. Read More

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http://dx.doi.org/10.14712/18059694.2019.135DOI Listing
April 2020
1 Read

Effect of Non-Surgical Periodontal Therapy on the Serum Sialic Acid Levels in Diabetic Patients with Periodontitis.

Acta Medica (Hradec Kralove) 2019 ;62(3):109-116

Division of Preventive Dentistry, Dental Health Department College of Applied Medical Science, King Saud University, Riyadh, Saudi Arabia.

Sialic acid (SA), a family of acetylated derivatives of neuraminic acid, an acute phase reactant by itself. It usually occurs as a terminal component at the non-reducing end of carbohydrate chains of glycoproteins and glycolipids. SA participates in multiple physiological functions, such as cell-to-cell interactions, cell migration and proliferation. Read More

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http://dx.doi.org/10.14712/18059694.2019.134DOI Listing
April 2020
9 Reads

Validation of the Slovakian version of Boston Carpal Tunnel Syndrome Questionnaire (BCTSQ).

Acta Medica (Hradec Kralove) 2019 ;62(3):105-108

Department of Public Health, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovak Republic.

Introduction: The most common occupational disease is carpal tunnel syndrome. The aim of this study was to translate and validate the Slovakian version of BCTSQ.

Methods: The original questionnaire was translated into the Slovakian language by two expert translators. Read More

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http://dx.doi.org/10.14712/18059694.2019.133DOI Listing
April 2020
1 Read

Monocyte to Lymphocyte Ratio, Neutrophil to Lymphocyte Ratio, and Red Cell Distribution Width are the Associates with Gouty Arthritis.

Acta Medica (Hradec Kralove) 2019 ;62(3):99-104

Division of Rheumatology, Department of Internal Medicine, Gazi University Faculty of Medicine, Ankara, Turkey.

Background: Neutrophils, monocytes, and macrophages activations are associated with a gout attack. Monocyte to lymphocyte ratio (MLR), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), red cell distribution width (RDW), and mean platelet volume (MPV) are well-known inflammation markers. In this study, we aimed to investigate whether they could be a predictive marker to the gout attack. Read More

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http://dx.doi.org/10.14712/18059694.2019.132DOI Listing
April 2020
1 Read

Rhinogenic Orbital Inflammation - What Has Changed over the Past 50 Years?

Acta Medica (Hradec Kralove) 2019 ;62(3):94-98

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Introduction: The purpose of the study was to compare the incidence, diagnostics, and treatment of rhinogenic inflammatory complications over the past 50 years.

Material And Methods: Retrospective study of 292 patients of ENT department, University hospital: Group A treated from 1966 to 1995, Group B treated from 1996 to 2015.

Results: Preseptal inflammation was the most common type (73% vs. Read More

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http://dx.doi.org/10.14712/18059694.2019.131DOI Listing

Foreign Bodies in the Abdominal Area: Review of the Literature.

Acta Medica (Hradec Kralove) 2019 ;62(3):85-93

Laboratory of Forensic Sciences, Democritus University of Thrace, School of Medicine, GR 68100 Dragana, Alexandroupolis, Greece.

The aim of this paper is to update and summarize the relevant literature on the anatomical localization, incidence, and diagnostic and therapeutic approaches to abdominal foreign bodies. A comprehensive review was carried out on recorded cases related to the presence of foreign bodies in the abdominal area throughout the literature. Moreover, the phenomenon was discussed in relation to different patient categories associated with childhood, mental or neurological illness, incarceration, and drug trafficking as well as sexual accident or abuse. Read More

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http://dx.doi.org/10.14712/18059694.2019.130DOI Listing
April 2020
1 Read

Interactions Between Anti-Vegf Therapy and Antitumor Immunity as a Potential Therapeutic Strategy in Colorectal Cancer.

Acta Medica (Hradec Kralove) 2019 19;62(3):127-130. Epub 2019 Aug 19.

Department of Oncology, Palacký University Medical School and Teaching Hospital, Olomouc, Czech Republic.

There is a growing corpus of evidence indicating that anti-VEGF therapy may normalize the abnormal tumor vasculature with the potential to re-program the tumor immune microenvironment to a more immunosupportive profile. Tumor vessel normalization increases tumor perfusion, and, consequently, oxygen and nutrient supply, and thus can be assumed to improve the general response to anticancer immunotherapy. The increased antitumor immunity responses seen following anti-VEGF therapy may also be associated with the inhibition of the immunosuppressive action deployed by VEGF on effector T cells. Read More

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http://dx.doi.org/10.14712/18059694.2019.129DOI Listing

Late-Onset Hypertrophic Pyloric Stenosis in a 14-Weeks-Old Full Term Male Infant.

Acta Medica (Hradec Kralove) 2019 ;62(2):82-84

Department of Pediatrics, University Hospital of Split, Split, Croatia.

Background: Hypertrophic pyloric stenosis is the most common cause of gastric outlet obstruction in infants, and classically presents at 2 to 6 weeks of age. Delayed presentation is an extremely rare occurrence after early infancy.

Case Report: A 14-weeks-old full term male infant presented with non-bilious vomiting, dehydration and hypocloremic metabolic alkalosis. Read More

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http://dx.doi.org/10.14712/18059694.2019.108DOI Listing
February 2020
4 Reads

Vulvo-Perineal and Perianal Paget Disease. Radical Excision and Reconstruction with Singapore Flap.

Acta Medica (Hradec Kralove) 2019 ;62(2):77-81

2nd Academic Department of General Surgery, Aretaieion Hospital, National & Kapodistrian University of Athens, Greece.

Extramammary Paget disease (EMPD) is an uncommon intraepithelial malignancy, affecting the vulvo-perineal and perianal region, occurring in 6.5% of all Paget diseases. Usually, an underlying invasive adenocarcinoma denotes a more aggressive behaviour of the disease. Read More

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http://dx.doi.org/10.14712/18059694.2019.107DOI Listing
February 2020
4 Reads

Abnormal Persistence of Embryonic Blood Supply of Liver: Anatomist's Delight, Surgeon's Nightmare.

Acta Medica (Hradec Kralove) 2019 ;62(2):72-76

Department of Anatomy, Maulana Azad Medical College, New Delhi, India.

The high incidence of hepato-biliary vascular anatomy variations necessitates its evaluation prior to performing liver transplantation, hepatobiliary, pancreatic, gastric and oesophageal surgeries. We report a unique case of persistence of embryonic arteries of the liver, wherein, the liver was supplied by five vessels. In addition to the usual right and left hepatic arteries from the hepatic artery proper, the liver received two accessory right hepatic arteries, one from the gastroduodenal artery, while another arising from superior mesenteric artery and an accessory left hepatic artery, from the left gastric artery. Read More

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http://dx.doi.org/10.14712/18059694.2019.106DOI Listing
February 2020

Non-Recurrent Right Laryngeal Nerve: a Rare Anatomic Variation Encountered During a Total Thyroidectomy.

Acta Medica (Hradec Kralove) 2019 ;62(2):69-71

University Department of Surgery, General and Oncologic Hospital of Kifissia "Agii Anargiri", Athens, Greece.

The non-recurrent laryngeal nerve (nRLN) is a rare anatomic variation that every head and neck surgeon must be aware of, in order to avoid intraoperative injury which leads to postoperative morbidity. We are reporting a case of a nRLN in a 47 year old female patient with medullary thyroid carcinoma who was surgically treated with total thyroidectomy and lymph node dissection. Both two inferior laryngeal nerves were identified, fully exposed and preserved along their cervical courses. Read More

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http://dx.doi.org/10.14712/18059694.2019.105DOI Listing
February 2020
2 Reads

The Interface Between Psychiatry and Ophthalmology.

Acta Medica (Hradec Kralove) 2019 ;62(2):45-51

Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Objective: The aim of this article is to review the interface between psychiatry and ophthalmology at several levels, such as the influence of psychopharmacology on eye disorders, the occurrence of psychiatric symptoms in eye diseases, and the neuroophthalmological examination methods supporting the validity of psychiatric diagnoses.

Materials And Methods: We searched the PubMed computer database for the key words "Psychiatry" and "Ophthalmology" on the 28th of August, 2018 to obtain relevant articles which were consequently summarized.

Results: The results showed that most patients with ocular disease simultaneously have one or more psychiatric symptoms. Read More

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http://dx.doi.org/10.14712/18059694.2019.104DOI Listing
February 2020
2 Reads

Calcemia and Inflammatory Markers in Early-Onset Neonatal Infection.

Acta Medica (Hradec Kralove) 2019 11;62(2):58-61. Epub 2019 Jun 11.

Department of Clinical Biochemistry, Klatovy Hospital, Klatovy, Czech Republic.

Introduction: Ionised hypocalcemia (S-Ca2+) has been repeatedly observed in neonates with sepsis. Our aim was to evaluate total calcemia (S-Ca) and its relationship to laboratory markers of infection.

Methods: We retrospectively evaluated total calcemia (S-Ca) and its relationship to laboratory markers of sepsis/infection (serum levels of C-reactive protein - S-CRP and procalcitonin - S-PCT) in 29 full-term neonates with early-onset neonatal infection hospitalized at our neonatology ward between 2012 and 2016. Read More

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https://actamedica.lfhk.cuni.cz/62/2/0058/
Publisher Site
http://dx.doi.org/10.14712/18059694.2019.47DOI Listing
February 2020
21 Reads

Dependence of Deciduous Tooth Eruption Terms and Tooth Growth Rate on the Weight-Height Index at Birth in Macrosomic Children over the First Year of Life.

Authors:
Olga Garmash

Acta Medica (Hradec Kralove) 2019 11;62(2):62-68. Epub 2019 Jun 11.

Kharkiv National Medical University, Therapeutic Dentistry Department, Ukraine.

The aim of this research is to study the effect of body overweight at birth (fetal macrosomia) on the processes of tooth eruption and tooth growth during the first year of life in children in the Kharkiv City (Ukraine) population. One of the research tasks is to examine the features of deciduous teeth eruption in children who were born with macrosomia with different values of the weight-height index at birth. Materials and methods. Read More

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http://dx.doi.org/10.14712/18059694.2019.48DOI Listing
February 2020
26 Reads

The Assessment of Serum Drug Levels to Diagnose Non-Adherence in Stable Chronic Heart Failure Patients.

Acta Medica (Hradec Kralove) 2019 23;62(2):52-57. Epub 2019 Apr 23.

Department of Internal Medicine, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic.

Background: The aim of our study was to evaluate the prevalence of drug non-adherence in stable chronic heart failure (CHF) patients using serum drug levels (SDL) assessment.

Methods: CHF patients were prospectively enrolled during scheduled outpatient visit. Except standard procedures an unanticipated blood sampling for the SDL assessment was obtained. Read More

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http://dx.doi.org/10.14712/18059694.2019.46DOI Listing
February 2020
2 Reads

Intradural Extramedullary Epidermoid Cyst at the Conus Medullaris Level with Thoracic Syringomyelia: A Case Report.

Acta Medica (Hradec Kralove) 2019 ;62(1):39-42

Firat University Hospital, Departments of Neurosurgery Elazig, Turkey.

Spinal epidermoid cysts are benign tumors. Syringomyelia secondary to intramedullary tumors are frequently observed. However, the association between syringomyelia and spinal intradural extramedullary epidermoid cyst in the conus medullaris region is extremely rare. Read More

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http://dx.doi.org/10.14712/18059694.2019.45DOI Listing
August 2019
10 Reads

Actinomycotic Endomyometritis Associated with a Long-Term Use of Intrauterine Device Lasting for 42 Years.

Acta Medica (Hradec Kralove) 2019 ;62(1):35-38

Department of Gynecology and Obstetrics, Faculty Hospital in Žilina, Slovakia.

In women, pelvic actinomycosis is closely associated with prolonged use of the intrauterine devices (IUD). A 70-year old female presented with intermittent blood-stained vaginal discharge. An analysis of her history revealed, she was inserted with an IUD 42 years ago, but it has remained in situ untill now. Read More

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http://dx.doi.org/10.14712/18059694.2019.44DOI Listing
August 2019
13 Reads

Cytotoxic Effects of Pistacia Atlantica (Baneh) Fruit Extract on Human KB Cancer Cell Line.

Acta Medica (Hradec Kralove) 2019 ;62(1):30-34

Department of Immunology and Shiraz Institute for Cancer Researches, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Plants with anticancer properties are considered as cancer preventive and treatment sources, due to their some biological effects. Apoptosis induction and anti-proliferative effects of Baneh extract on various cancer cell lines have been reported. Hence, this study was designed to evaluate the cytotoxic effects of this fruit on KB and human gingival fibroblast cell lines (HGF). Read More

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https://actamedica.lfhk.cuni.cz/62/1/0030/
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http://dx.doi.org/10.14712/18059694.2019.43DOI Listing
August 2019
37 Reads

Thoracic Radiography Characteristics of Drug Sensitive Tuberculosis and Multi Drug Resistant Tuberculosis: A Study of Indonesian National Tuberculosis Prevalence Survey.

Acta Medica (Hradec Kralove) 2019 ;62(1):24-29

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia.

Background: Tuberculosis (TB) remains a burden globally, including Indonesia. The primary objective of this study is to reveal the chest radiography characteristic of drug-sensitive TB (DS-TB) and multi-drug resistant TB (MDR-TB) in the Indonesian national tuberculosis prevalence survey 2013-2014. The secondary objective is to explore the correlation and incidence rate of chest radiography lesion of DS-TB and MDR-TB cases. Read More

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http://dx.doi.org/10.14712/18059694.2019.42DOI Listing
August 2019
9 Reads

Nightstick Fractures, Outcomes of Operative and Non-Operative Treatment.

Acta Medica (Hradec Kralove) 2019 ;62(1):19-23

Royal Derby Hospital, Derby, United Kingdom.

Introduction: A nightstick fracture is an isolated fracture of the ulnar shaft. Although operative and non-operative treatments have been commonly decided by the degree of displacement of the fracture, still there is a controversy specially in those moderately displaced. Herein we report our experience with nightstick fractures. Read More

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http://dx.doi.org/10.14712/18059694.2019.41DOI Listing
August 2019
2 Reads

Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome.

Acta Medica (Hradec Kralove) 2019 ;62(1):12-18

Department of Clinical Biochemistry, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey.

Background: Fibromyalgia syndrome (FMS) is an extra-articular rheumatological disease, characterized by widespread pain and somatic symptoms. The etiology has not yet been clarified. Oxidative stress may play an important role in FMS etiology. Read More

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http://dx.doi.org/10.14712/18059694.2019.40DOI Listing
August 2019
5 Reads

Prevalence of Musculoskeletal Disorders Symptoms Among Czech Dental Students. Part 2: The Predictive Value of Digital Assessment.

Acta Medica (Hradec Kralove) 2019 ;62(1):6-11

Department of Rehabilitation and Sports Medicine, Charles University, 2nd Faculty of Medicine, and Motol University Hospital, Prague, Czech Republic.

This article is the second part of an evaluation of musculoskeletal disorders (MSDs) prevalence among dental students. As the majority of complaints are in the back region, there is an endeavor to analyze objectively the disorders in this region. One of the non-invasive and non-radiation methods is the spinal curve mapping using the Spinal Mouse® device (Idiag AG, Fehraltorf, Switzerland). Read More

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http://dx.doi.org/10.14712/18059694.2019.39DOI Listing
August 2019
5 Reads

Dual Tracer 99mTc-Pertechnetate/99mTc-MIBI Dual-Time-Point SPECT/CT Parathyroid Gland Assessment Regarding to Parathyroid Gland Size and Biochemical Parameters - Two Years Single Imaging Centre Experience.

Acta Medica (Hradec Kralove) 2019 ;62(1):1-5

Nuclear Medicine Department, University Hospital Hradec Králové, Czech Republic.

Introduction: Preoperative parathyroid imaging is inevitable part of focused parathyroid surgery. The aim of our study was assessment of parathyroid scintigraphy diagnostic accuracy regarding to size and metabolic parameters of hyperfunctioning parathyroid tissue.

Material And Methods: Parathyroid scintigraphy for suspected primary hyperparathyroidism was performed in 95 patients during years 2015 and 2016. Read More

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https://actamedica.lfhk.cuni.cz/62/1/0001/
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http://dx.doi.org/10.14712/18059694.2019.38DOI Listing
August 2019
33 Reads

Pharyngeal Papilloma: a Rare Non-Pulmonary Cause of Hemoptysis.

Acta Medica (Hradec Kralove) 2018;61(4):158-161

Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.

The most common benign neoplasm of the pharynx is papilloma. It is characterized by bulging brittle lesions, which are pedicled or sessile, whitish-grey or pinkish colour. Progressive hoarseness is the main clinical feature. Read More

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http://dx.doi.org/10.14712/18059694.2018.136DOI Listing
July 2019
3 Reads

Primary Hepatic Leiomyosarcoma: a Case Report and Review of the Literature.

Acta Medica (Hradec Kralove) 2018;61(4):153-157

Second Department of Propedeutic Surgery, "Laiko" General Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.

Background/aim: Primary hepatic leiomyosarcoma is an extremely rare type of liver sarcoma with relatively poor prognosis, with about 50 cases having been reported in the literature. Potential origins of this tumor in the liver are the smooth muscle cells in the round ligament, intrahepatic blood vessels and intrahepatic bile ducts. There is no apparent sex predilection and there is a wide age range. Read More

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http://dx.doi.org/10.14712/18059694.2018.135DOI Listing
July 2019
4 Reads

Anaplastic Carcinoma Thyroid in a Young Child - an Extremely Rare Occurrence.

Acta Medica (Hradec Kralove) 2018;61(4):150-152

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Anaplastic thyroid carcinoma (ATC), one of the most aggressive malignancies, is extremely rare in childhood. We present a case of 5-yearold child who presented with rapidly progressing thyroid swelling and stridor, for which she underwent emergency tracheostomy and biopsy. Histopathological features were suggestive of ATC and the patient died within two months after diagnosis. Read More

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http://dx.doi.org/10.14712/18059694.2018.134DOI Listing
July 2019
12 Reads

Topiramate Reduces Aortic Cross-Clamping-Induced Lung Injury in Male Rats.

Acta Medica (Hradec Kralove) 2018;61(4):144-149

Camlica Erdem Hospital, Department of Internal Medicine, Istanbul, Turkey.

Background: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) injury. We aimed to evaluate whether TPM prevents damage occurring in lung tissue during I/R. Read More

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http://dx.doi.org/10.14712/18059694.2018.133DOI Listing
July 2019
4 Reads

Histological Features of Oral Cavity Mucous Membrane Epithelium in Six-Month-Old Experimental Animals Born with Macrosomia.

Acta Medica (Hradec Kralove) 2018;61(4):137-143

Institute of Physiology of the Czech Academy of Sciences, Department of Biomathematics, Czech Republic.

We examined the histological features of the mucobuccal fold of oral cavity mucous membrane from the area of the masticatory teeth roots' projection in 6-month-old Wistar Albino Glaxo rats with fetal macrosomia. The animals were divided into groups according to the body weight, the body length, and the Quetelet index at birth. A morphological study was performed using the Leica SP8 AOBS laser scanning confocal microscope and a conventional light (Axiostar, Zeiss) microscopy. Read More

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https://actamedica.lfhk.cuni.cz/61/4/0137/
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http://dx.doi.org/10.14712/18059694.2018.132DOI Listing
July 2019
8 Reads

Prevalence of Musculoskeletal Disorders Symptoms among Czech Dental Students. Part 1: a Questionnaire Survey.

Acta Medica (Hradec Kralove) 2018;61(4):131-136

Department of Rehabilitation and Sports Medicine, Charles University, 2nd Faculty of Medicine, and Motol University Hospital, Prague, Czech Republic.

Musculoskeletal disorders (MSDs) frequently occur among dentists and dental students. The first aim of this study was to gather and analyze information about the prevalence of symptoms of MSDs. The second aim was to determine a correlation between subjectively described complaints and the results of an objective examination of the spine using the Spinal Mouse® device; that part is described in the second section of this article. Read More

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http://dx.doi.org/10.14712/18059694.2018.131DOI Listing
July 2019
4 Reads

Epidemiological Profile and Antimicrobial Resistance Pattern of Enteric Fever in a Tertiary Care Hospital of North India - a Seven Year Ambispective Study.

Acta Medica (Hradec Kralove) 2018;61(4):125-130

Army College of Medical Sciences and Base Hospital, New Delhi, India.

Introduction: Enteric-fever is a major public-health problem in developing countries emerging as multidrug-resistant, Nalidixic-acid resistant and extremely drug-resistant Salmonella (Pakistan, 2016), has intensified the use of WHO watch/reserve group antimicrobials such as azithromycin and meropenem.

Methods: This ambispective-study was conducted on 782 non-repeat blood-culture isolates of S. Typhi, S. Read More

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http://dx.doi.org/10.14712/18059694.2018.130DOI Listing
July 2019
4 Reads

Patients' Expectations in Lens Extraction Surgery: a Systematic Review.

Acta Medica (Hradec Kralove) 2018;61(4):115-124

Department of Ophthalmology, University Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.

It is common knowledge that there are patients who have an uncomplicated cataract surgery with an actual improvement of their visual acuity, but they are dissatisfied with their final visual capacity. It is hypothesized that patients' preoperative expectations play a significant role in their postoperative perceptions. A systematic review of the recent literature regarding preoperative expectations of patients before lens extraction surgery and their postoperative perceptions as regards the visual outcome was performed based on the PubMed, Medline, Google Scholar, American Academy of Ophthalmology, Nature and Springer databases in September 2017 and data from 14 descriptive and 7 comparative studies were included in this narrative review. Read More

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http://dx.doi.org/10.14712/18059694.2018.129DOI Listing
July 2019
7 Reads

Polyneuropathy, Myocardial Dysfunction and Pericardial Effusion Following Duodenal Switch.

Acta Medica (Hradec Kralove) 2018;61(3):111-113

Department of Medicine E, Sheba Medical Center, Tel-Hashomer affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.

Duodenal Switch procedure is a type of bariatric surgery that was reserved for severely morbid obese people. Patients undergoing this procedure are at high risk for nutrient deficiencies. In this report we present a case of a patient who had developed polyneuropathy, generalized muscle weakness, Wernicke encephalopathy, myocardial dysfunction and pericardial effusion six years following this operation. Read More

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http://dx.doi.org/10.14712/18059694.2018.128DOI Listing
July 2019
11 Reads

Adult Bochdalek Hernia with Organo-Axial Gastric Volvulus: Misdiagnosed as Hydropneumothorax.

Acta Medica (Hradec Kralove) 2018;61(3):108-110

Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Bochdalek hernia (BH) in an adult may manifest clinically with a myriad of abdominal or chest symptoms or a combination of them. Diagnosis of an adult BH is usually delayed in view of rarity of the lesion and its varied presentation. A 30-year-old adult gentleman presented to us with a left thoracostomy which was draining pus and ingested food particles. Read More

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http://dx.doi.org/10.14712/18059694.2018.127DOI Listing
July 2019
7 Reads