7,987 results match your criteria Acta cytologica[Journal]


Primary Synovial Sarcoma of the Thyroid: Challenges in Cytologic Diagnosis and Review of the Literature.

Acta Cytol 2020 May 26:1-9. Epub 2020 May 26.

Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA.

Background: Primary synovial sarcoma (SS) of the thyroid (PSST) is extremely rare. Its differential diagnosis from other neoplasms is essential since it has different management protocols and prognosis.

Case: A 26-year-old man with a 4. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000507312DOI Listing

COVID-19 and Nasal Cytobrush Cytology.

Acta Cytol 2020 May 26:1-2. Epub 2020 May 26.

Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000508768DOI Listing

A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology: The Sydney System.

Acta Cytol 2020 May 26:1-17. Epub 2020 May 26.

Department of Medicine and Surgery, Università degli Studi di Salerno, Fisciano, Salerno, Italy,

Background: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC.

Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506497DOI Listing

Prospective Comparison of Intraoperative Touch Imprint Cytology and Frozen Section Histology on Axillary Sentinel Lymph Nodes in Early Breast Cancer Patients.

Acta Cytol 2020 May 25:1-6. Epub 2020 May 25.

Department of Pathology, Tajimi City Hospital, Tajimi, Japan.

Introduction: Since the late 1970s, sentinel lymph node biopsy (SLNB) has been used for several solid malignancies to identify lymph node metastases. This procedure is associated with less surgical morbidity than complete lymphadenectomy. Recent evidence suggests that axillary lymphadenectomy is not required for breast sentinel nodes with micrometastases (≤2 mm). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000508016DOI Listing

Interobserver Agreement for the International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology.

Acta Cytol 2020 May 19:1-7. Epub 2020 May 19.

University of Utah Health Care and ARUP Laboratories, Salt Lake City, Utah, USA.

Background: A number of guidelines have been developed to improve standardization of the terminology and criteria for cytologic specimens obtained from the thyroid, pancreas, lung, and salivary glands. A major goal of these guidelines is to improve reproducibility and understanding of the reporting of diagnostic results among cytopathologists and between cytopathologists and clinicians. The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology (IAC YSRB) is the most recent of these guidelines. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506757DOI Listing

Application of the International System for Reporting Serous Fluid Cytopathology (ISRSFC) on Reporting Pericardial Effusion Cytology.

Acta Cytol 2020 May 18:1-9. Epub 2020 May 18.

Department of Pathology, Division of Cytopathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA,

Introduction: The International System for Reporting Serous Fluid Cytopathology (ISRSFC) has recently been announced. Pericardial effusion (PE) is a clinical manifestation of a large variety of both neoplastic and non-neoplastic conditions. Herein, we have applied the ISRSFC on reporting PE cytopathology and report our experience in a large academic institution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000507311DOI Listing

Does YouTube Provide Reliable and High-Quality Information? Assessment of Pap Smear Test Videos.

Acta Cytol 2020 May 12:1-8. Epub 2020 May 12.

Nisantasi Vocational School, Istanbul, Turkey.

Aim: YouTube is one of the most popular video-sharing platforms and is used by many people as a source of information regarding health conditions. Although there are many studies examining YouTube health-related videos in terms of quality, content and accuracy, there is not any study observing the content of YouTube videos about the "Pap smear test." Therefore, we intended to evaluate YouTube videos related to the Pap smear test. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000507105DOI Listing

Comparison Study of Self-Sampled and Physician-Sampled Specimens for High-Risk Human Papillomavirus Test and Cytology.

Acta Cytol 2020 May 12:1-9. Epub 2020 May 12.

Department of Gynecology, Hokkaido Ohno Memorial Hospital, Sapporo, Japan.

Objective: The objective of this study was to calculate the positive rate and overall concordance rate of high-risk human papillomavirus (hrHPV) test and cytology using self-sampled and physician-sampled cervicovaginal tests and to compare both specimens.

Methods: In collaboration with 3 private hospitals in Sapporo city, 300 women visiting these organizations were enrolled in the study by previously signing an informed consent. From these women, both types of samples (self-obtained and physician-sampled) were obtained at the same time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000507342DOI Listing

Comparison of Genotoxic Effect in Buccal Exfoliated Cells between Cigarette and Waterpipe Smokers.

Acta Cytol 2020 Apr 21:1-6. Epub 2020 Apr 21.

Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran,

Background/aim: Cytogenetic biomarkers such as micronuclei (MN) are used for the evaluation of exposure to carcinogens and genotoxic effects in oral epithelial cells. Tobacco is one of the strongest carcinogens responsible for the development of cancer in oral mucosa. The aim of this study was to compare the genotoxic effect of waterpipe smoking with that of cigarette smoking. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506893DOI Listing

Current Topics and Practical Considerations of Cytology Practice in Lung Cancer: Reflexions from the Lung Symposium at the 42nd European Congress of Cytology, Malmö, 2019.

Acta Cytol 2020 Apr 7:1-8. Epub 2020 Apr 7.

Institute of Pathology, University Hospital of Cologne, Cologne, Germany.

In June 2019, a lung symposium was held at the 42nd European Congress of Cytology in Malmö, Sweden. Due to the current importance of cytological samples in the diagnoses and molecular analysis to set up the utmost management of lung cancer patients, cytologists from different countries shared the experience of their institutions. The place of the cytological samples gains more and more importance on the potential long-term survival gain through personalized medicine and this harbors the improvement of the guidelines both in pathology and cytology field. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506724DOI Listing

Pericardial Fluid Cytology: A Rosettey Affair….

Acta Cytol 2020 Apr 6:1-4. Epub 2020 Apr 6.

Department of Pathology, Homi Bhabha Cancer Hospital, Sangrur, India,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506726DOI Listing

HPV Genotype Prevalence and Success of Vaccination to Prevent Cervical Cancer.

Acta Cytol 2020 Apr 1:1-5. Epub 2020 Apr 1.

Genoa/LPCM Laboratory, São Paulo, Brazil.

Background: Nearly 500,000 new cases of cervical cancer are estimated annually worldwide. Three vaccines are currently licensed to prevent cervical cancer. The success of vaccination depends mainly on the prevalence of HPV genotypes, and many cases of HPV infection have been diagnosed after vaccination. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506725DOI Listing

Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and Japanese Society of Clinical Cytology: An Interobserver Reproducibility Study and Risk of Malignancy Evaluation on Cytology Specimens.

Acta Cytol 2020 Mar 27:1-11. Epub 2020 Mar 27.

Department of Thoracic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.

Introduction: The classification of lung carcinoma is based on small biopsies and/or cytology in 80% of patients with non-small cell carcinoma. However, there is no widely accepted classification system for respiratory cytology. The Japan Lung Cancer Society (JLCS) and Japanese Society of Clinical Cytology (JSCC) have proposed a new four-tiered cytology reporting system for lung carcinoma with the following categories: (1) "negative for malignancy," (2) "atypical cells," (3) "suspicious for malignancy," and (4) "malignancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506431DOI Listing

Phaeohyphomycosis: Cytomorphologic Evaluation in Eleven Cases.

Acta Cytol 2020 Mar 23:1-7. Epub 2020 Mar 23.

Government Medical College and Hospital, Chandigarh, India.

Objective: Phaeohyphomycosis caused by phaeoid fungi is a type of mycosis emerging worldwide which causes a wide variety of clinical manifestations.

Study Design: A retrospective analysis of 11 cases diagnosed with fungal inflammation on cytology over a period of 6 years (2013-2018) was done along with culture/histopathologic confirmation.

Results: Of the total of 11 cases, 9 cases presented with subcutaneous swellings and 1 case each with brain and lung lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506432DOI Listing

Intracytoplasmic Lumen in Urine Cytology Predicts Worse Prognosis in Non-Muscle-Invasive Bladder Cancers.

Acta Cytol 2020 Feb 25:1-8. Epub 2020 Feb 25.

Department of Laboratory Medicine and Pathology, Kanazawa Medical University, Uchinada, Japan.

Background: Intracytoplasmic lumina (ICL) are observed in several cancers, including urothelial carcinoma (UC). We have reported that ICL in urine cytology (cICL) is more frequent in high-grade UCs than in low-grade UCs; however, the correlation between the presence of ICL and prognosis is unclear.

Objectives: The aim of this work was to determine the association between cICL and prognosis in bladder cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000505955DOI Listing
February 2020

Smartphone-Assisted Telecytopathology: An Intraobserver Concordance Study.

Acta Cytol 2020 Feb 19:1-7. Epub 2020 Feb 19.

Department of Pathology, University College of Medical Sciences, Delhi University, Delhi, India.

Introduction: Telecytology is the practice of cytology at a distance. The images captured by a camera are sent to the cytopathologist at a different location who views the images and reaches a diagnosis. Recently, smartphone-assisted telepathology has been evaluated for different subspecialities of pathology including cytology for second opinion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506145DOI Listing
February 2020
1.562 Impact Factor

Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears.

Acta Cytol 2020 Jan 21:1-3. Epub 2020 Jan 21.

Institute of Pathology, University of Bern, Bern, Switzerland.

Rapid on-site evaluation (ROSE) is one of cytopathology's "unique selling propositions." The quality, speed, and ease of handling of the staining used is a critical factor for the efficacy of the ROSE procedure. Here, we describe a modification of rapid toluidine blue staining that can be performed within 25 s, provides excellent nuclear morphology, and is compatible with subsequent Papanicolaou staining of the slides. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000505254DOI Listing
January 2020

Kikuchi-Fujimoto Disease-Like Inflammatory Reaction in a Silicone Breast Implant Seroma.

Acta Cytol 2020 Jan 21:1-4. Epub 2020 Jan 21.

Department of Pathology, University Hospital 12 de Octubre, Madrid, Spain.

Introduction: Kikuchi-Fujimoto disease (KFD) may have an autoimmune etiology and some cases have been associated with silicone breast implants. Cytomorphologic features of the disease have been well characterized by fine-needle aspiration of lymph nodes. They are so specific as to permit a precise cytologic diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000505253DOI Listing
January 2020

Self-Sampling as a Plausible Alternative to Screen Cervical Cancer Precursor Lesions in a Population with Low Adherence to Screening: A Systematic Review.

Acta Cytol 2020 Jan 20:1-12. Epub 2020 Jan 20.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal,

Background: Cervical cancer is the fourth most common cancer in the world. A raised incidence and mortality parallel a low participation rate in screening, namely screening in poor countries and among specific populations of developed countries. Cervical or vaginal self-sampling may increase adherence to screening due to its low costs and elevated sensibility and specificity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000505121DOI Listing
January 2020
1.562 Impact Factor

The Role of Telecytology in the Primary Diagnosis of Thyroid Fine-Needle Aspiration Specimens.

Acta Cytol 2019 Nov 1:1-9. Epub 2019 Nov 1.

IPATIMUP, Institute of Molecular Pathology and Immunology of University of Porto, Porto, Portugal.

Introduction: The Acibadem Health Group (AHG) has been using telepathology/digital pathology stations since 2006. In 2013, the system was changed from videoconferencing to digital pathology (whole-slide imaging) utilizing 3DHISTECH scanners and software. In 2017, digital cytology started to be used for routine cytopathologic diagnosis for thyroid fine-needle aspiration (FNA) cases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503914DOI Listing
November 2019

Detection of Anaplastic Lymphoma Kinase-Rearranged Mesothelioma Cells in Ascites by Companion Diagnostics.

Acta Cytol 2019 Oct 29:1-8. Epub 2019 Oct 29.

Department of Diagnostic Pathology, Osaka Red Cross Hospital, Osaka, Japan.

Background: A case of peritoneal mesothelioma with an anaplastic lymphoma kinase (ALK) translocation was identified, and we conducted further studies to obtain diagnostic and therapeutic insights. We believe that this is the first report describing the cytology of this new tumor type.

Case: A teenage woman was referred for severe pleural effusion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503663DOI Listing
October 2019
1 Read

Residual Metal Contaminants in Endoscopic Ultrasound-Guided Fine-Needle Aspiration.

Acta Cytol 2019 Oct 23:1-3. Epub 2019 Oct 23.

Pathology Section, Rashid Hospital, Dubai, United Arab Emirates,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503915DOI Listing
October 2019

Variants of Papillary Thyroid Carcinoma: An Algorithmic Cytomorphology-Based Approach to Cytology Specimens.

Acta Cytol 2019 Oct 21:1-11. Epub 2019 Oct 21.

Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.

Background: Thyroid cancer accounts for 1% of cancer cases in developed countries, in which papillary thyroid carcinoma (PTC) is the most common type. There are multiple variants of PTC described to date, some of them with aggressive behavior and poor clinical outcome. These variants are well described and accepted in recent guidelines of many international societies, and the prognostic and management implications are well laid out. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503576DOI Listing
October 2019
1 Read

Effects of the Storage Solution Type and Prolonged Storage on the Immunoreactivity of Cells.

Acta Cytol 2019 Oct 9:1-8. Epub 2019 Oct 9.

Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan.

Introduction: In effusion cytology, immunocytochemistry is a useful staining approach to provide important information for diagnosis. Effusion cytology is performed not only for pleural effusions and ascites but also for peritoneal and needle washing from fine needle aspirations or instruments. Although various solutions are used for washing cytology, the effect of the solution type on immunocytochemical reactivity is not fully understood. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503268DOI Listing
October 2019
1 Read

Comparison of the Efficacy of Sediment Cytology over Oral Brush Cytology in Oral Leukoplakia.

Acta Cytol 2019 Oct 8:1-7. Epub 2019 Oct 8.

Department of Oral Pathology, Maratha Mandal's NGH Institute of Dental Sciences and Research Center, Belgaum, India.

Introduction: A method called sediment cytology includes the investigation of smears arranged from the sediment of the biopsy specimen fixatives. The sediment from this fixative is used to prepare smears and provides a potentially rich source for cytological material. Investigation of the fixative sediment and understanding of the cytological picture with pertinent clinical and radiological information permits diagnosis in a few hours. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000503216DOI Listing
October 2019
1 Read
1.562 Impact Factor

Fine-Needle Aspiration Cytology of the Testes for the Classification of Azoospermia and Its Value in the Assessment of Male Infertility.

Acta Cytol 2020 24;64(3):216-223. Epub 2019 Sep 24.

Topiwala National Medical College, Department of Pathology, B.Y.L. Nair Charitable Hospital, Mumbai, India,

Background: Infertility is an ever-increasing problem in today's world. It can be due to male or female causes. Azoospermia seen in 5-10% of infertile men is due to obstructive or non-obstructive causes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502790DOI Listing
May 2020
3 Reads

Brush Cytology Performance for the Assessment of Biliopancreatic Strictures.

Acta Cytol 2019 Sep 24:1-8. Epub 2019 Sep 24.

Gastroenterology Department, Centro Hospitalar São João, Porto, Portugal.

Introduction: Brush cytology is commonly used during endoscopic retrograde cholangiopancreatography for the diagnostic evaluation of biliopancreatic strictures. However, since the overall sensitivity of brush cytology is poor, the exclusion of malignancy is difficult. Recognition of factors related to the patient, technique or lesion may help improve the diagnostic yield of brush cytology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502791DOI Listing
September 2019
2 Reads

Cytology in Anal Cancer Screening: Practical Review for Clinicians.

Acta Cytol 2019 Sep 18:1-7. Epub 2019 Sep 18.

Faculty of Medicine of the University of Porto, Porto, Portugal,

The incidence and mortality of anal squamous cell carcinoma (SCC) are expected to continue to increase in the next 20 years. High-risk groups for anal SCC, i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502881DOI Listing
September 2019
2 Reads

Extensive Emperipolesis of Neoplastic Lymphocytes by Mesothelial Cells in Pleural Effusion Cytology in a Case of a Mediastinal T-Cell Lymphoblastic Lymphoma: A Rare but Diagnostically Useful Phenomenon.

Acta Cytol 2020 17;64(3):274-278. Epub 2019 Sep 17.

Institute of Pathology, University Hospital Basel, Basel, Switzerland,

Emperipolesis is a biological process defined by the presence of an intact cell within the cytoplasm of another cell. In pleural fluid cytology, the phenomenon is very rare but has already been described in B-cell lymphoma. Here, we report the first case of a T-cell lymphoma diagnosed on a pleural fluid exhibiting extensive emperipolesis of tumor cells by mesothelial cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502711DOI Listing
May 2020
2 Reads

Role of Ancillary Testing on Endoscopic US-Guided Fine Needle Aspiration Samples from Cystic Pancreatic Neoplasms.

Acta Cytol 2020 11;64(1-2):124-135. Epub 2019 Sep 11.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Pancreatic cysts are increasingly detected on imaging studies. Accurate determination of the cyst type is important to provide appropriate care for the patients. It is also very clear that not one single modality can provide adequate diagnostic information. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502372DOI Listing
January 2020
2 Reads

Colon Tumor Tattooing-Derived Ink-Laden Macrophages in Peritoneal Ascitic Fluid.

Acta Cytol 2020 11;64(3):270-273. Epub 2019 Sep 11.

Department of Pathology, University Hospital La Paz, Madrid, Spain.

Introduction: Macrophages containing exogenous pigments are commonly encountered in cytological specimens.

Case Presentation: We present a case of tumor tattooing as an infrequent exogenous source of peritoneal fluid macrophagic pigment in a 76-year-old female.

Discussion And Conclusion: Tattooing-derived ink can be a source of macrophagic pigment and should not be confused with other endogenous or exogenous pigments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502505DOI Listing

Cytopathology Comes of Age.

Acta Cytol 2020 9;64(1-2):5-6. Epub 2019 Sep 9.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502373DOI Listing
January 2020

Performance of Laboratories after 10 Years of Participating in External Quality Monitoring in Cervical Cytology.

Acta Cytol 2020 3;64(3):224-231. Epub 2019 Sep 3.

School of Pharmacy, Federal University of Goiás, Goiânia, Brazil,

Objective: To evaluate the performance of laboratories accredited by the National Health System that perform cytopathology examination of the uterine cervix after 10 years of participation in external quality monitoring (eQM).

Study Design: Seven laboratories were assessed in this study. To assess the concordance of the representation of epithelia and results, 6,536 examinations (3,433 in 2007 and 3,103 in 2017) were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502433DOI Listing
May 2020
1 Read

New Cell Block Method to Enhance the Cellular Yield in Mucous and/or Bloody Samples.

Acta Cytol 2020 30;64(3):265-269. Epub 2019 Aug 30.

Department of Pathology, Fimlab Laboratories, Tampere University Hospital, Tampere, Finland,

Objective: Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501817DOI Listing
May 2020
2 Reads

A Diagnostic Approach to Endometrial Cytology by Means of Liquid-Based Preparations.

Acta Cytol 2020 30;64(3):195-207. Epub 2019 Aug 30.

Clinical Cytopathology Service, Istituto Cantonale di Patologia, Locarno, Switzerland.

The adoption of endometrial cytology as a diagnostic procedure has been hampered in the past by difficulties arising in interpreting the cellular findings due to a number of factors (such as excess blood, cellular overlapping, and the complex physiology of endometrium). Recently, the use of liquid-based cytology (LBC), with its ability to remove blood and mucus and to distribute cells uniformly in a thin layer on the slide, has provided an opportunity to reevaluate the role of endometrial cytology. LBC samples are easier to screen compared to conventional ones, due to a smaller screening area and an excellent quality of cell preparations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000502108DOI Listing

DNA Ploidy Analysis and Cell Block Immunohistochemistry in the Diagnosis of Malignant Effusions.

Acta Cytol 2020 29;64(3):256-264. Epub 2019 Aug 29.

Saint Peter's University Hospital, New Brunswick, New Jersey, USA.

Background: Effusion cytology is a major diagnostic tool in medicine and has both therapeutic and prognostic implications. One of the dilemmas encountered is the differentiation between atypical cells and reactive mesothelial cells. The use of ancillary tools can reduce this grey zone and help to achieve a definitive diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501790DOI Listing
May 2020
1.562 Impact Factor

Ultrasound-Guided Transthoracic Fine-Needle Aspiration: A Reliable Tool in Diagnosis and Molecular Profiling of Lung Masses.

Acta Cytol 2020 30;64(3):208-215. Epub 2019 Jul 30.

Department of Pathology, Division of Cytopathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA.

Introduction: Pulmonary adenocarcinoma is a major cause of mortality worldwide. The majority of patients present with advanced stage disease, and minimally invasive procedures are desirable for diagnosis and treatment plans. Herein, we report our experience with percutaneous/transthoracic needle aspiration (TT-NA) in the cytologic diagnosis of pulmonary adenocarcinoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501421DOI Listing
May 2020
11 Reads

Diagnostic Value of the EZH2 Immunomarker in Malignant Effusion Cytology.

Acta Cytol 2020 26;64(3):248-255. Epub 2019 Jul 26.

Department of Pathology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia,

Background: Differentiating reactive mesothelial cells from metastatic carcinoma in effusion cytology is a challenging task. The application of at least 4 monoclonal antibodies including 2 epithelial markers (Ber-EP4, MOC-31, CEA, or B72.3) and 2 mesothelial markers (calretinin, WT-1, CK5/6, or HBME-1) are often useful in this distinction; however, it is not readily available in many resource-limited developing countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501406DOI Listing
May 2020
6 Reads

Pleural Effusion in Pulmonary and Extrapulmonary Blastomycosis.

Acta Cytol 2020 2;64(3):241-247. Epub 2019 Jul 2.

Department of Pathology, Rush University Medical Center, Chicago, Illinois, USA.

Objective: Pleural effusion secondary to blastomycosis infection is an uncommon clinical manifestation of the disease. We undertook a retrospective study to assess the incidence and involvement of pleural effusion in patients with blastomycosis infection.

Study Design: Institutional cytology and surgical pathology records were searched from December 1995 to October 2017 for cases of blastomycosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500973DOI Listing
May 2020
5 Reads

Liquid Biopsy: A New Tool in Oncology.

Acta Cytol 2019 2;63(6):448. Epub 2019 Jul 2.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501355DOI Listing
October 2019
4 Reads

Characterizing the Effect of Automated Cell Sorting Solutions on Cytomorphological Changes.

Acta Cytol 2020 24;64(3):232-240. Epub 2019 Jun 24.

Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan.

Introduction: Liquid-based cytology has become a widely adopted, automated screening system for gynecologic and nongynecologic cytology. Automated screening systems function by distinguishing atypical cells based on their cytoplasmic and nuclear areas, densitometric measurement, and so on. However, the morphological influence of the washing solution has not been fully considered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500769DOI Listing
May 2020
6 Reads

Announcement: The International System for Reporting Serous Fluid Cytopathology.

Acta Cytol 2019 24;63(5):349-351. Epub 2019 Jun 24.

Medical Faculty, Porto University, Porto, Portugal.

Serous fluids are a common but important specimen type in a cytopathology laboratory. There is as yet no agreed standardized terminology to allow uniformity in reporting on these specimens. Given that serous fluids are a rich source of cytopathological as well as molecular information on a range of benign and often advanced malignant conditions, a unified approach to handling and reporting these specimens covering the pre-analytical, analytical and postanalytical stages seems timely. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501536DOI Listing
September 2019
15 Reads

Cytodiagnostic Sensitivity of Fine Needle Aspiration Biopsy for Hodgkin's Lymphoma Is Decreased in Patients with Human Immunodeficiency Virus Infection.

Acta Cytol 2019 24;63(5):352-360. Epub 2019 Jun 24.

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA,

Objective: We aimed to evaluate the sensitivity of fine needle aspiration (FNA) for the diagnosis of Hodgkin's lymphoma (HL) in HIV-infected patients.

Study Design: An electronic search was conducted to retrospectively identify patients diagnosed with HL who underwent FNA followed by confirmatory biopsy. FNAs were categorized as negative, atypical/suspicious/positive, or nondiagnostic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501098DOI Listing
September 2019
16 Reads

Utility of Squash Cytology in Spinal Lesions with Special Reference to Ki67 Immunostain.

Acta Cytol 2019 24;63(5):424-430. Epub 2019 Jun 24.

Department of Neurosurgery, IPGME&R and SSKM Hospital and Bangur Institute of Neurosciences, Kolkata, India.

Background: Squash cytology is of significant importance in intraoperative consultation of central nervous system (CNS) pathology. There are several studies on squash cytology of CNS lesions, and only a few of them deal with spinal lesions alone.

Aims: (1) To evaluate intraoperative squash cytology of spinal lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500681DOI Listing
September 2019
11 Reads

Genomic Alterations in Undifferentiated Malignant Tumors with Rhabdoid Phenotype and Loss of BRG1 Immunoexpression Identified by Fine Needle Aspirates.

Acta Cytol 2019 21;63(5):438-444. Epub 2019 Jun 21.

Department of Pathology, The University of Chicago, Chicago, Illinois, USA,

Objective: Evidence shows that the switch/sucrose nonfermenting chromatin remodeling complex plays a critical role in DNA repair, cancer progression and dedifferentiation. BRG1 is one of its key catalytic subunits. While the loss of BRG1 expression by immunocytochemistry has been identified in a subset of malignancies arising in various sites with undifferentiated/rhabdoid morphology and poor prognosis, the underlying basis for its loss is unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500684DOI Listing
September 2019
17 Reads

A Clinical Trial to Verify the Efficiency of the LC-1000 Exfoliative Cell Analyzer as a New Method of Cervical Cancer Screening.

Acta Cytol 2019 19;63(5):391-400. Epub 2019 Jun 19.

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan,

Objective: The exfoliative cell analyzer, LC-1000 (Sysmex Corporation, Japan), is a medical device that presents the cell proliferation index and 23 research parameters as indicators of cellular proliferative potential. The objective was to evaluate the clinical usability of qualitative assessment by LC-1000 compared with cytology, the human papillomavirus (HPV) test, and histology as gold standard.

Study Design: Women that visited 3 sites between July 2015 and March 2017 were registered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501118DOI Listing
September 2019
3 Reads

HPV-ISH-Negative Invasive Cervical Squamous Cell Carcinoma: Histologic and Pap Test Results.

Acta Cytol 2019 13;63(5):417-423. Epub 2019 Jun 13.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA,

Introduction: A causal link between infection with a high-risk strain of human papilloma virus (hrHPV) and the development of cervical squamous cell carcinoma (SCC) is well established. However, a small number of SCCs are hrHPV-negative by either HPV co-DNA testing and/or HPV-in situ hybridization (HPV-ISH) at the time of diagnosis. These apparently hrHPV-negative lesions are poorly understood, specifically whether hrHPV-positive precursor lesions exist, which would be detected through hrHPV-based screening. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500595DOI Listing
September 2019
5 Reads

What Has Changed Since the Introduction of Human Papillomavirus Testing with the Cytology-Based Cervical Cancer Screening System in Japan A Social Experiment.

Acta Cytol 2019 4;63(5):385-390. Epub 2019 Jun 4.

Department of Obstetrics and Gynecology, Faculty of Medicine, Saga University, Saga, Japan.

Background: Uterine cervical cancer is the fourth most common female cancer in the world. In Japan, we have an apparently low rate of joining cervical cancer screening programs compared with Western countries. Furthermore, the incidence and mortality rate of cervical cancer among the younger generation has been increasing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500190DOI Listing
September 2019
17 Reads

Histopathology and Cytopathology of Neuroendocrine Tumors and Carcinomas of the Breast: A Review.

Acta Cytol 2019 4;63(4):340-346. Epub 2019 Jun 4.

Department of Anatomical Pathology, St Vincent's Hospital, Sydney, New South Wales, Australia.

Neuroendocrine tumors (NET) and carcinomas (NEC) of the breast are rare diseases, but NEC has attracted attention in both cytopathology and surgical pathology because of its specific management and prognosis. Fine-needle aspiration biopsy (FNAB) cytology can make the diagnosis in many cases particularly with high-grade NEC, with definitive diagnosis based on histopathology and immunohistochemistry. This review describes the characteristics of the disease based on the WHO classification 2012 and recent literature and -includes discussion related to the International Academy of Cytology Yokohama System of Reporting Breast FNAB -cytology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500705DOI Listing
July 2019
3 Reads