650,074 results match your criteria Acta crystallographica. Section F Structural biology and crystallization communications[Journal]


Eotaxins and C-C chemokine receptor type 3 in Parkinson's disease.

Acta Neurol Belg 2018 Dec 13. Epub 2018 Dec 13.

Geriatric Care Research Center, Rafsanjan University of Medical Science, Rafsanjan, Iran.

Parkinson's disease (PD) is one of the most common neuroinflammatory disorders and inflammatory processes seem to play an important role in the pathogenesis of PD. Chemokines as inflammatory mediators, which are involved in the recruitment of leukocytes, can play a role in the pathogenesis of PD. The aim of this study was to examine the serum level of eotaxins (CCL11, CCL24, and CCL26) and the expression of C-C chemokine receptor type 3 (CCR3) in patients with PD compared with healthy subjects. Read More

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December 2018

Relationship of leptin, growth hormone, and insulin-like growth factor levels with body mass index and disease severity in patients with fibromyalgia syndrome.

Acta Neurol Belg 2018 Dec 13. Epub 2018 Dec 13.

Physical Medicine and Rehabilitation Clinic, Bingöl State Hospital, Bingöl, Turkey.

Objective: A high prevalence of obesity in fibromyalgia syndrome (FMS) predisposes patients to metabolic changes. It is not clear how the clinical manifestations of the disease affect metabolism. This study aimed to investigate leptin, growth hormone (GH), and insulin-like growth factor (IGF-1) levels in FMS, and their relationship with body mass index (BMI) and disease severity. Read More

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December 2018

Efficiency and complications of Woven EndoBridge (WEB) devices for treatment of larger, complex intracranial aneurysms-a single-center experience.

Acta Neurochir (Wien) 2018 Dec 13. Epub 2018 Dec 13.

Institute of Clinical Medicine, University in Oslo, Problemveien 17, 0315, Oslo, Norway.

Background: Several recently published multicenter studies have reported high treatment feasibility, high safety, and good 6-month to 1-year efficiency when treating smaller intracranial aneurysms (IA) with WEB deployment. The purpose of the study was to evaluate the long-term efficiency and complications related to WEB treatment of larger, complex intracranial aneurysms in a small single-center cohort.

Methods: Patients with ruptured and unruptured IA were treated with WEB devices; data were collected prospectively and analyzed retrospectively. Read More

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December 2018

Correction to: Intracranial foreign material granuloma after neurosurgical procedures.

Acta Neurochir (Wien) 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurosurgery, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hanover, Germany.

Incorrect title of the article. Read More

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December 2018

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

Acta Neuropathol 2018 Dec 13. Epub 2018 Dec 13.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Göteborgsvägen 31, House V3/SU, 43180, Mölndal, Sweden.

Tau is an axonal microtubule-binding protein. Tau pathology in brain and increased tau concentration in the cerebrospinal fluid (CSF) are hallmarks of Alzheimer's disease (AD). Most of tau in CSF is present as fragments. Read More

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December 2018

Modifiable Risk-factors for Keratinocyte Cancers in Australia: A Case-control Study.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Department of Clinical Epidemiology and Applied Biostatistics, University Hospital Tübingen, DE-72076 Tübingen, Germany.

Keratinocyte cancer (KC) is the most common malignancy in Caucasians. The incidence of KC has increased over the past 40 years. This case-control study investigated the environmental and host risk-factors responsible for development of KC in Australia's high-risk population. Read More

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December 2018

Energy Dispersive X-Ray Fluorescence Zn/Fe Ratiometric Determination of Zinc Levels in Expressed Prostatic Fluid: A Direct, Non-Invasive and Highly Accurate Screening for Prostate Cancer.

Acta Sci Cancer Biol 2018 Nov 10;2(9):20-26. Epub 2018 Oct 10.

The Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Maryland, United States of America.

Prostate specific antigen (PSA) does not provide the reliability that is required for the accurate urology screening of prostate cancer (PCa). Consequently, there has been a major focus and search for a simple, rapid, direct, preferably non-invasive, and highly accurate biomarker and procedure for the urology screening for prostate cancer. Virtually all PCa cases exhibit a marked decrease in zinc in prostate tissue and in prostatic fluid. Read More

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November 2018

T-plate fixation for unstable proximal clavicula fractures.

Acta Orthop Traumatol Turc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedics, Ningbo, People's Republic of China.

Objective: The aim of this study was to evaluate the clinical results of T-plate fixation and anterior sternoclavicular ligament repair in proximal clavicle fractures.

Methods: Between August 2013 and August 2016, a total 12 patients (10 men and 2 women; mean age: 44.1 ± 9. Read More

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December 2018

Subglottic stenosis due to chronic lymphocytic leukemia.

Acta Otorrinolaringol Esp 2018 Dec 10. Epub 2018 Dec 10.

Department of Otolaryngology, Toranomon Hospital, Tokyo Japan.

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December 2018

Progression of carotid artery disease could stratify a risk of coronary artery disease patients with type 2 diabetes.

Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.

Institute for Health and Sport, Victoria University, Melbourne VIC, Australia.

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December 2018

A novel detection method of Cryptosporidium parvum infection in cattle based on Cryptosporidium parvum virus 1.

Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.

Key Laboratory of Zoonosis by Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.

Cryptosporidium parvum is an important zoonotic parasite that causes significant economic loss in the animal husbandry industry, especially the cattle industry. As there is no specific vaccine or drug against Cryptosporidium, a rapid and accurate method for the detection of C. parvum is of great significance. Read More

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December 2018

Advanced glycation end products of bovine serum albumin affect the cell growth of human umbilical vein endothelial cells via modulation of MEG3/miR-93/p21 pathway.

Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.

Department of Cardiac Surgery, Ruijin Hospital, Shanghai, China.

Advanced glycation end products of BSA (AGE-BSA) contribute to the pathogenesis of diabetic vascular diseases. However, the roles and underlying mechanisms of AGE-BSA in diabetic vascular diseases remain largely unclear. Long non-coding RNAs (lncRNAs) are widely identified and known as gene regulators. Read More

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December 2018

Short-term propamocarb exposure induces hepatic metabolism disorder associated with gut microbiota dysbiosis in adult male zebrafish.

Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.

Department of Biotechnology, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.

Propamocarb (PM) is a pesticide that is widely used to protect cucumbers and other plants from downy mildew. Recently, some studies indicated that PM exposure had potential toxic effects in animals. In this study, adult male zebrafish were exposed to 100 and 1000 μg/l PM for 7 days to assess its effects on metabolism and the gut microbiota. Read More

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December 2018

Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathway.

Acta Biochim Biophys Sin (Shanghai) 2018 Dec 13. Epub 2018 Dec 13.

Core Research Program 1515, Key Laboratory for Food Science and Biotechnology of Hunan Province, College of Food Science and Technology, Hunan Agricultural University, Changsha, China.

Lotus seed is well known as traditional food and medicine, but its skin is usually discarded. Recent studies have shown that lotus seed skin contains a high concentration of proanthocyanidins that have multi-functions, such as antioxidation, anti-inflammation, and anti-cancer effects. In the present study, we aimed to isolate and purify the proanthocyanidins from lotus seed skin by acetone extraction and rotary evaporation, identify their chemical structures by HPLC-MS-MS and NMR, and further investigate the antioxidant properties of the extract purified by macroporous resin (PMR) from lotus seed skin both in vitro and in vivo. Read More

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December 2018

Adaptation of Alpha-Papillomavirus over Millennia.

Acta Cytol 2018 Dec 13:1-3. Epub 2018 Dec 13.

Papillomaviruses (PVs) are a group of small DNA viruses that, with around 350 million years of evolution, acquired the capacity of infecting a broad range of vertebrates, including humans. To date, more than 300 PV types have been isolated. Viruses that have a long common evolutionary history with their host typically cause unapparent infections. Read More

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December 2018

Subcutaneous Fat Necrosis of the Newborn: Is Fine Needle Aspiration Cytology Diagnostic?

Acta Cytol 2018 Dec 13:1-3. Epub 2018 Dec 13.

Department of Paediatric Surgery, Chacha Nehru Bal Chikitsalaya, Delhi, India.

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December 2018

Photoluminescent properties in perylene PVD films: Influence of molecular aggregates and supramolecular arrangement.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 4;211:221-226. Epub 2018 Dec 4.

Department of Physics, School of Technology and Applied Sciences, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil. Electronic address:

Organic thin films are at the forefront of basic studies and applications in the field of physics, chemistry, biochemistry and materials science. For example, the intrinsic supramolecular arrangement, or simply the formation of aggregates may alter the optical and electrical properties, which would impact the potential applications of the material. Here, an attempt is made to correlate the molecular structures of two perylene derivatives, bis butylimido perylene (BuPTCD) and bis phenethylimido perylene (PhPTCD), with their film formation, in particular, the supramolecular arrangement and the photoluminescent properties. Read More

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December 2018

Does the wavelength dependent photoisomerization process of the p‑coumaric acid come out from the electronic state dependent pathways?

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 5;211:203-211. Epub 2018 Dec 5.

State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. Electronic address:

Similar to the anion photoactive yellow protein (PYP) chromophore, the neutral form of the PYP chromophore was also found to exhibit a the wavelength-dependent photoisomerization quantum yield. The isomerization quantum yield increases with the increasing excitation energy on the S state, while decreases when being excited to the S state. Does this wavelength dependent product yield come out from the specific reaction pathways of the S and S states? This would mean that, the relaxation pathway of the S state is distinct from that of the S state and does not involve twisting motion. Read More

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December 2018

Tea types classification with data fusion of UV-Vis, synchronous fluorescence and NIR spectroscopies and chemometric analysis.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 1;211:195-202. Epub 2018 Dec 1.

Department of Geoinformation, Adam Mickiewicz University, Dzięgielowa 27, Poznań, Poland.

The potential of selected spectroscopic methods - UV-Vis, synchronous fluorescence and NIR as well a data fusion of the measurements by these methods - for the classification of tea samples with respect to the production process was examined. Four classification methods - Linear Discriminant Analysis (LDA), Quadratic Discriminant Analysis (QDA), Regularized Discriminant Analysis (RDA) and Support Vector Machine (SVM) - were used to analyze spectroscopic data. PCA analysis was applied prior to classification methods to reduce multidimensionality of the data. Read More

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December 2018

Looking deep into nature: A review of micro-computed tomography in biomimicry.

Acta Biomater 2018 Dec 10. Epub 2018 Dec 10.

Laboratory of Functional Morphology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.

Albert Einstein once said "look deep into nature, and then you will understand everything better". Looking deep into nature has in the last few years become much more achievable through the use of high-resolution X-ray micro-computed tomography (microCT). The non-destructive nature of microCT, combined with three-dimensional visualization and analysis, allows for the most complete internal and external "view" of natural materials and structures at both macro- and micro-scale. Read More

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December 2018

A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation.

Biochim Biophys Acta Proteins Proteom 2018 Dec 10. Epub 2018 Dec 10.

Department of Biochemistry, University of Delhi South Campus, New Delhi 110021, India. Electronic address:

Acyl carrier proteins (ACPs) play crucial roles in the biosynthesis of fatty acids, non-ribosomal polypeptides and polyketides. The three-dimensional NMR structure of Leishmania major holo-LmACP, belonging to the type II pathway, has been reported previously, but the structure of its apo-form and its conformational differences with the holo-form remain to be explored. Here we report the crystal structures of apo-LmACP (wild-type and S37A mutant) at 2. Read More

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December 2018

Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice.

Biochim Biophys Acta Mol Basis Dis 2018 Dec 10. Epub 2018 Dec 10.

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, IL, USA; Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA. Electronic address:

Hexokinase domain containing 1, a recently discovered putative fifth hexokinase, is hypothesized to play key roles in glucose metabolism. Specifically, during pregnancy in a recent genome wide association study (GWAS), a strong correlation between HKDC1 and 2-h plasma glucose in pregnant women from different ethnic backgrounds was shown. Our earlier work also reported diminished glucose tolerance during pregnancy in our whole body HKDC1 heterozygous mice. Read More

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December 2018

The stability and oncogenic function of LIN28A are regulated by USP28.

Biochim Biophys Acta Mol Basis Dis 2018 Dec 10. Epub 2018 Dec 10.

Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea; College of Medicine, Hanyang University, Seoul 04763, South Korea. Electronic address:

RNA-binding protein LIN28A is often highly expressed in human malignant tumors and is involved in tumor metastasis and poor prognosis. Knowledge about post-translational regulatory mechanisms governing LIN28A protein stability and function is scarce. Here, we investigated the role of ubiquitination and deubiquitination on LIN28A protein stability and report that LIN28A protein undergoes ubiquitination. Read More

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December 2018

STAC proteins: The missing link in skeletal muscle EC coupling and new regulators of calcium channel function.

Biochim Biophys Acta Mol Cell Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Physiology and Medical Physics, Medical University Innsbruck, Schöpfstraße 41, A6020 Innsbruck, Austria.

Excitation-contraction coupling is the signaling process by which action potentials control calcium release and consequently the force of muscle contraction. Until recently, three triad proteins were known to be essential for skeletal muscle EC coupling: the voltage-gated calcium channel Ca1.1 acting as voltage sensor, the SR calcium release channel RyR1 representing the only relevant calcium source, and the auxiliary Ca β subunit. Read More

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December 2018

Correlation between active disease and hypercoagulability state in patients with systemic lupus erythematosus.

Clin Chim Acta 2018 Dec 10. Epub 2018 Dec 10.

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address:

Objective: This study has investigated whether high levels of Reticulocytes-C4d (R-C4d) and Platelets-C4d (P-C4d) reflecting recent activity in SLE patients are correlated with changes in natural anticoagulation components, coagulation activation and endothelial injury markers.

Methods: This study included three groups: 1) healthy women (control, n = 30); 2) women with low activity of the disease (SLEDAI 2 K ≤ 4, n = 30); 3) women with active disease (moderate or high activity) (SLEDAI 2 K > 4, n = 30). Median fluorescence intensity (MFI) of R-C4d and P-C4d were determined by flow cytometry using double labeling with specific monoclonal antibodies. Read More

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December 2018

Monitoring novel modified hemoglobin using mass spectrometry contributes to accurate blood glucose management of the Han Chinese population.

Clin Chim Acta 2018 Dec 10. Epub 2018 Dec 10.

Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing, China. Electronic address:

Background: The goal of this study was to detect novel modified forms of hemoglobin using mass spectrometry (MS) and to investigate the effect of modified hemoglobin on HbA1c and fasting plasma glucose (FPG).

Methods: This study was conducted on 1200 subjects aged >25 years. Hemoglobin from the above-mentioned subjects was detected using direct-infusion electrospray ionization-MS, and HbA1c and FPG were measured according to the manufacturer's instructions. Read More

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December 2018

In vitro lipid transfer assays of phosphatidylinositol transfer proteins provide insight into the in vivo mechanism of ligand transfer.

Biochim Biophys Acta Biomembr 2018 Dec 10. Epub 2018 Dec 10.

Department of Chemistry and Centre for Biotechnology, Brock University, St. Catharines, Ontario L2A 3S1, Canada. Electronic address:

Fluorescence resonance energy transfer (FRET) assays and membrane binding determinations were performed using three phosphatidylinositol transfer proteins, including the yeast Sec14 and two mammalian proteins PITPα and PITPβ. These proteins were able to specifically bind the fluorescent phosphatidylcholine analogue NBD-PC ((2-(12-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl-1-hexadecanoyl-sn-glycero-3-phosphocholine)) and to transfer it to small unilamellar vesicles (SUVs). Rate constants for transfer to vesicles comprising 100% PC were slower for all proteins than when increasing percentages of phosphatidylinositol were incorporated into the same SUVs. Read More

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December 2018

Prevalence and molecular characterization of Sarcocystis infections of retail beef products from central China.

Acta Trop 2018 Dec 10. Epub 2018 Dec 10.

College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471023, China.

Cattle are the intermediate hosts for five Sarcocystis species including S. hominis and S. heydorni, which also infect humans. Read More

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December 2018
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Heterogeneity in the acquisition of naturally acquired antibodies to cell-traversal protein for ookinetes and sporozoites (CelTOS) and thrombospondin-related adhesion protein (TRAP) of Plasmodium falciparum in naturally infected patients from unstable malaria areas in Iran.

Acta Trop 2018 Dec 10. Epub 2018 Dec 10.

Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran.

Currently, there is no subunit malaria vaccine capable of providing long-lasting protection, and a vaccine based on a single-antigen has shown moderate to unsatisfactory efficacies in clinical trials. As in malaria elimination and eradication strategies, the primary objective is reduction in disease and death due to P. falciparum, in the present investigation, for the first time, we attempted to determine and compare the naturally acquired immune responses to two well-recognized sporozoite antigens, cell-traversal protein for ookinetes and sporozoites (CelTOS) and thrombospondin-related adhesion protein (TRAP), in P. Read More

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December 2018

Plasma levels of VEGF-A, VEGF B, and VEGFR-1 and applicability of these parameters as tumor markers in diagnosis of breast cancer.

Acta Biochim Pol 2018 Dec 13. Epub 2018 Dec 13.

Medical University of Bialystok.

The VEGF family members are important factors in promoting angiogenesis and lymphangiogenesis in malignant processes. The aim of this study was to investigate plasma concentrations of VEGF-A, VEGF-B and their soluble VEGFR-1 receptor and their diagnostic utility and potency as compared to CA 15-3 in breast cancer patients and in relation to the control group. The study included 120 breast cancer patients and 60 control patients. Read More

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December 2018

Polyneuropathy, Myocardial Dysfunction and Pericardial Effusion Following Duodenal Switch.

Acta Medica (Hradec Kralove) 2018 ;61(3):111-113

Department of Medicine E, Sheba Medical Center, Tel-Hashomer affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.

Duodenal Switch procedure is a type of bariatric surgery that was reserved for severely morbid obese people. Patients undergoing this procedure are at high risk for nutrient deficiencies. In this report we present a case of a patient who had developed polyneuropathy, generalized muscle weakness, Wernicke encephalopathy, myocardial dysfunction and pericardial effusion six years following this operation. Read More

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January 2018

Adult Bochdalek Hernia with Organo-Axial Gastric Volvulus: Misdiagnosed as Hydropneumothorax.

Acta Medica (Hradec Kralove) 2018 ;61(3):108-110

Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Bochdalek hernia (BH) in an adult may manifest clinically with a myriad of abdominal or chest symptoms or a combination of them. Diagnosis of an adult BH is usually delayed in view of rarity of the lesion and its varied presentation. A 30-year-old adult gentleman presented to us with a left thoracostomy which was draining pus and ingested food particles. Read More

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January 2018

Quality of Life after Reconstructive Surgery for Intestinal Fistulas.

Acta Medica (Hradec Kralove) 2018 ;61(3):103-107

Department of Gerontology and Metabolism, Teaching Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Background: This retrospective clinical study would like to objectively denote a quality of life of persons afflicted by an abdominal catastrophe and managed by an extensive surgery can be almost as well conformable as those of healthy people in a similar age group.

Methods: A set of eighteen patients who were successfully surgically treated and cured enjoyed a relatively good convalescence after their surgery and returned to a satisfactory standard of life from the point of view of organ function and psychosomatic state. Statistical analysis of the data collected over a period of 1 to 6 years after this complex therapy using special questionnaire for QOL assessment SF-36 was performed. Read More

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January 2018

Next Generation Sequencing in Molecular Diagnosis of Lynch Syndrome - a Pilot Study Using New Stratification Criteria.

Acta Medica (Hradec Kralove) 2018 ;61(3):98-102

Department of Molecular Biology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Slovakia.

The development of the new technologies such as the next-generation sequencing (NGS) makes more accessible the diagnosis of genetically heterogeneous diseases such as Lynch syndrome (LS). LS is one of the most common hereditary form of colorectal cancer. This autosomal dominant inherited disorder is caused by deleterious germline mutations in one of the mismatch repair (MMR) genes - MLH1, MSH2, MSH6 or PMS2, or the deletion in the EPCAM gene. Read More

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January 2018

Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of Pulmonary Embolism) Study Programme.

Acta Medica (Hradec Kralove) 2018 ;61(3):93-97

Department of Internal Medicine, St. Vincenz and Elisabeth Hospital Mainz (KKM), Mainz, Germany.

An acute pulmonary embolism (PE) is a crucial event in patients' life and connected with serious morbidity and mortality. Regarding a high case-fatality rate, early and accurate risk-stratification is crucial. Risk for mortality and complications are closely related to hemodynamic stability and cardiac adaptations. Read More

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January 2018

Soluble Tumor Necrosis Factor (TNF)-Like Weak Inducer of Apoptosis (Tweak) Independently Predicts Subclinical Atherosclerosis in Behcet's Disease.

Acta Medica (Hradec Kralove) 2018 ;61(3):86-92

Division of Rheumatology, Department of Internal Medicine, Malatya State Hospital, Malatya, Turkey.

Background: Vasculopathy is a major cause of mortality and morbidity in Behcet's Disease (BD). Subclinical atherosclerosis can even be detected in the early stage of BD. Soluble tumor necrosis factor-like (TNF) weak inducer of apoptosis (TWEAK) is known as a good marker of the inflammation in vascular tree. Read More

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January 2018

Endothelial Dysfunction in Children with Juvenile Psoriatic Arthritis.

Acta Medica (Hradec Kralove) 2018 ;61(3):79-85

Department of Dermatology, A. Reiman's Hospital, Prešov, Slovakia.

Background: To evaluate the presence of endothelial dysfunction in Slovak children with juvenile psoriatic arthritis in the absence of classic cardiovascular risk factors in order to assess its relationship to the disease activity and disability.

Methods: 25 juvenile psoriatic arthritis patients (JPSA) and 25 healthy controls aged 6-19 years were enrolled into this study. In all subjects vascular measurements over a period of three years (January 2013 - January 2016) were performed, in accordance with the guidelines for ultrasonographic evaluation of FMD% (flow-mediated endothelial dependent vasodilatation) of the brachial artery. Read More

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January 2018

Unusual Congenital Multiple Clustered Dermatofibroma: First Reported Case on the Face.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, 36-1 Nishicho, Yonago, Tottori 683-8504, Japan.

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December 2018

Beliefs About Medicines in Patients with Psoriasis Treated with Methotrexate or Biologics: A Cross-sectional Survey Study.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Radboud university medical center, 6500 HB Nijmegen, The Netherlands.

Methotrexate (MTX) and biologics are frequently used treatments for psoriasis. Exploring patients' beliefs about their treatment may help to elucidate patients' attitudes towards these therapies. A cross-sectional survey was conducted using the Beliefs about Medicines Questionnaire-Specific (BMQ-Specific) in patients treated with methotrexate or biologics. Read More

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December 2018

Voltammetric immunoassay of human IgG based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres.

Mikrochim Acta 2018 Dec 12;186(1):15. Epub 2018 Dec 12.

Hubei Key Laboratory of Pollutant Analysis & Reuse Technology, Department of Chemistry, Hubei Normal University, Huangshi, 435002, People's Republic of China.

The authors describe a nanocomposite that was obtained by in-situ deposition of CdS nanocrystals on mesoporous silica nanospheres (MSNs), and its use in an electrochemical immunoassay of human immunoglobulin G (HIgG). The MCN/CdS nanocomposite was covalently modified with the antibodies against HIgG and then employed in a voltammetric immunoassay at antibody-functionalized magnetic beads. Through sandwich immunoreaction, the MCN/CdS nanoprobes are quantitatively captured onto the magnetic beads where numerous Cd(II) ions are released in an acidic solution. Read More

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December 2018

The evaluation of the sense of hearing in patients with carotid artery stenosis within the extracranial segments.

Acta Neurol Belg 2018 Dec 12. Epub 2018 Dec 12.

Uniwersytet Medyczny im Piastow Slaskich we Wroclawiu, Wrocław, Dolnośląskie, Poland.

Stenosis of arteries that supplies blood to the brain is one of the main causes of ischemic stroke which is the third most common cause of deaths in Europe. Atherosclerosis of carotid and vertebral arteries is responsible for 20% of the ischemic stroke cases. Stenosis may be either asymptomatic or manifested with typical neurological symptoms including motor and sensory disturbances as well as disturbances in vision and speech. Read More

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December 2018

Is there a relationship between restless legs syndrome and medical problems in pregnant women? A cross-sectional study in Iran.

Acta Neurol Belg 2018 Dec 12. Epub 2018 Dec 12.

Midwifery Department, Menopause Andropause Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

This study aimed to assess the relationship between RLS and medical problems among pregnant women. In this study, 700 pregnant women were recruited. A socio-demographic questionnaire and the International Restless Legs Questionnaire were used to gather information. Read More

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December 2018

A composite prepared from a metal-organic framework of type MIL-101(Fe) and morin-modified magnetite nanoparticles for extraction and speciation of vanadium(IV) and vanadium(V).

Mikrochim Acta 2018 Dec 12;186(1):14. Epub 2018 Dec 12.

Department of Physics, Iran University of Science and Technology, Narmak, Tehran, 16844, Iran.

A novel magnetic metal-organic framework (MOF) consisting of MIL-101(Fe) and morin-modified magnetite nanoparticles was synthesized and utilized for the extractive speciation analysis of V(IV) and V(V) at trace levels. The magnetic MOF exhibits selectivity toward V(V) at pH = 5.8. Read More

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December 2018

Gold nanorods decorated with graphene oxide and multi-walled carbon nanotubes for trace level voltammetric determination of ascorbic acid.

Mikrochim Acta 2018 Dec 12;186(1):17. Epub 2018 Dec 12.

School of Chemistry and Materials Science, Ludong University, Yantai, 264025, People's Republic of China.

An ultra-sensitive sensor is described for the voltammetric determination of ascorbic acid (AA). A glassy carbon electrode (GCE) was modified with graphene oxide (GO), multi-walled carbon nanotubes (MWCNTs) and gold nanorods (AuNRs). GO was used to prevent the aggregation of MWCNTs. Read More

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December 2018

Pituitary adenoma apoplexy associated with vardenafil intake.

Acta Neurochir (Wien) 2018 Dec 12. Epub 2018 Dec 12.

Department of Neurological Surgery, Dentistry, and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

Vardenafil is a potent phosphodiesterase-5 (PDE-5) inhibitor used in the treatment of erectile dysfunction. Several cases of stroke related to the use of PDE-5 inhibitors have been reported. Here, we describe the case of a 51-year-old man with headache and right ophthalmoplegia subsequent to vardenafil consumption. Read More

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December 2018

Silver nanoclusters functionalized with Ce(III) ions are a viable "turn-on-off" fluorescent probe for sulfide.

Mikrochim Acta 2018 Dec 12;186(1):16. Epub 2018 Dec 12.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, 999078, China.

The authors show that silver nanoclusters functionalized with Ce(III) ions are a viable fluorescent probe for selective and sensitive detection of sulfide at pH 7.0. The blue fluorescence of silver nanoclusters (with excitation/emission peaks at 358/426 nm) is enhanced on the addition of Ce(III) ions but is quenched in the presence of a trace concentrations of sulfide. Read More

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December 2018

Dynamic contrast-enhanced magnetic resonance imaging may act as a biomarker for vascular damage in normal appearing brain tissue after radiotherapy in patients with glioblastoma.

Acta Radiol Open 2018 Nov 9;7(11):2058460118808811. Epub 2018 Nov 9.

Department of Radiology, Surgical Sciences, Uppsala University, Uppsala, Sweden.

Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a promising perfusion method and may be useful in evaluating radiation-induced changes in normal-appearing brain tissue.

Purpose: To assess whether radiotherapy induces changes in vascular permeability (K) and the fractional volume of the extravascular extracellular space (V) derived from DCE-MRI in normal-appearing brain tissue and possible relationships to radiation dose given.

Material And Methods: Seventeen patients with glioblastoma treated with radiotherapy and chemotherapy were included; five were excluded because of inconsistencies in the radiotherapy protocol or early drop-out. Read More

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November 2018

Thermosensitive, fast gelling, photoluminescent, highly flexible, and degradable hydrogels for stem cell delivery.

Acta Biomater 2019 Jan 26;83:96-108. Epub 2018 Oct 26.

Department of Materials Science and Engineering, The Ohio State University, 2041 College Road, Columbus, OH, USA; Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO 63130, USA. Electronic address:

Stem cell therapy is a promising approach to regenerate ischemic cardiovascular tissues yet experiences low efficacy. One of the major causes is inferior cell retention in tissues. Injectable cell carriers that can quickly solidify upon injection into tissues so as to immediately increase viscosity have potential to largely improve cell retention. Read More

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January 2019

Review of titanium surface modification techniques and coatings for antibacterial applications.

Acta Biomater 2019 Jan 26;83:37-54. Epub 2018 Oct 26.

LBPS/CSPBAT, UMR CNRS 7244, Institut Galilée, Université Paris 13, Sorbonne Paris Cité, 99 Avenue JB Clément, 93340 Villetaneuse, France.

Implanted biomaterials play a key role in the current success of orthopedic and dental procedures. Pure titanium and its alloys are the most commonly used materials for permanent implants in contact with bone. However, implant-related infections remain among the leading reasons for failure. Read More

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January 2019

Nanofiber arrangement regulates peripheral nerve regeneration through differential modulation of macrophage phenotypes.

Acta Biomater 2019 Jan 27;83:291-301. Epub 2018 Oct 27.

Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Electronic address:

Topographical cues presented by aligned nanofibers have been demonstrated to stimulate peripheral nerve regeneration across long gaps, but the underlying mechanisms remain incompletely elucidated. Because macrophages play a crucial role in peripheral nerve regeneration and can be phenotypically modulated by topographical cues, we hypothesized that aligned nanofibers might induce the development of macrophage phenotypes that facilitate the regeneration of peripheral nerves. Here, macrophages were seeded on aligned and random poly(l-lactic acid-co-ε-caprolactone) nanofibers and their morphology and phenotypes were compared. Read More

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January 2019
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