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    4411 results match your criteria Acta cardiologica[Journal]

    1 OF 89

    Percutaneous repair of mitral valve regurgitation in patients with severe heart failure: comparison with optimal medical treatment.
    Acta Cardiol 2017 Nov 21:1-9. Epub 2017 Nov 21.
    a Department of Internal Medicine III, Division of Cardiology , Im Neuenheimer Feld 410, University of Heidelberg , Heidelberg , Germany.
    Background: Occurrence of severe mitral valve (MV) regurgitation (MR) is an independent negative predictor of mortality in patients with severe systolic heart failure (HF). This study examines clinical effects and cardiac reverse remodelling in patients with severe systolic HF receiving percutaneous mitral valve repair (PMVR) using MitraClip in comparison to patients receiving optimal medical therapy only.

    Methods: Between 2010 and 2014, 86 patients (Society of Thoracic Surgeons score: 10. Read More

    Quality assessment in percutaneous coronary interventions: the QERMID Belgian PCI registry.
    Acta Cardiol 2017 Nov 10:1-4. Epub 2017 Nov 10.
    d Department of Cardiovascular medicine , University Hospitals Leuven , Leuven , Belgium.
    Background: The recent increase in the number of interventional cathlabs that followed a moratorium of several years has resulted in an abrupt increase in the number of PCI and a dilution of the experience per centre and per operator.

    Methods: Based on data extracted from the national "Quality Oriented Electronic Registration of Medical Implant Devices" (QERMID) database, we compared the characteristics and outcome of patients treated in 2015 in the 21 newly (<3 years) approved PCI centres with those of patients treated in the 28 historical PCI centres.

    Results: The proportion of acute coronary syndromes was slightly higher in new than in historical centres (48% vs. Read More

    Kidney function is associated with short-term, mid-term and long-term clinical outcome after coronary angiography and intervention.
    Acta Cardiol 2017 Oct 30:1-8. Epub 2017 Oct 30.
    b Karolinska Institutet, Department of Clinical Sciences , Danderyd University Hospital , Stockholm , Sweden.
    Background: Patients with kidney dysfunction are at risk of developing ischaemic heart disease. We investigated the association between eGFR and early-, mid- and long-term clinical outcome in patients undergoing coronary angiography and intervention.

    Methods: Retrospective study on 4968 patients with complete data on eGFR, 65% male and aged 32-80 years, admitted to Danderyd University Hospital, Stockholm, Sweden for coronary angiography and intervention from 2006 to 2008. Read More

    Association of QRS duration with left ventricular volume and ejection fraction after anterior myocardial infarction assessed by gated single photon emission computed tomography.
    Acta Cardiol 2017 Oct 26:1-6. Epub 2017 Oct 26.
    a Department of Cardiovascular Medicine , Hiroshima University Graduate School of Biomedical and Health Sciences , Hiroshima , Japan.
    Background: Even intermediate QRS prolongation without bundle branch block is associated with worse clinical outcome after myocardial infarction (MI). We assessed the association of QRS duration with left ventricular (LV) volume and ejection fraction after anterior MI by using quantitative gated single photon emission computed tomography (SPECT).

    Methods: Eighty-two patients with prior anterior MI were enrolled. Read More

    The prognostic value of high sensitive cardiac troponin I in patients receiving cardiac resynchronisation therapy.
    Acta Cardiol 2017 Oct 12:1-6. Epub 2017 Oct 12.
    a Cardiology Clinic, Arrhythmology department , East Slovak Institute for Cardiac and Vascular Diseases , Kosice , Slovakia.
    Background: Cardiac troponin I (cTnI) is a valuable prognostic biomarker in patients with chronic heart failure (CHF). However, the prognostic importance of cTnI in patients who received cardiac resynchronisation therapy (CRT) remains unknown. The aim of this prospective study was to determine the prognostic value of high-sensitive cTnI (hs-cTnI) in CHF patients receiving CRT. Read More

    Drugs in cardiac arrest: the rise and fall of antiarrhythmics.
    Acta Cardiol 2017 Oct 12:1-3. Epub 2017 Oct 12.
    b Hellenic Society of Cardiopulmonary Resuscitation.
    Since the publication of 2000 guidelines for resuscitation, amiodarone is considered the antiarrhythmic drug of choice for refractory ventricular fibrillation/pulseless ventricular tachycardia. However, to date there is no proven benefit in terms of neurologically intact survival to hospital discharge. A comprehensive search of the recent literature on amiodarone, nifekalant and lidocaine in cardiac arrest was performed. Read More

    Electrical support during outdoor cycling in patients with coronary artery disease: impact on exercise intensity, volume and perception of effort.
    Acta Cardiol 2017 Oct 10:1-8. Epub 2017 Oct 10.
    a Faculty of Medicine and Life Sciences , Hasselt University, Agoralaan gebouw D , Diepenbeek , Belgium.
    Background: Electrical assisted bicycles (EAB's) could be used to overcome barriers and difficulties to outdoor cycling and thus assist in achieving a sufficient physical activity level in coronary artery disease (CAD) patients, but it is unknown whether sufficient exercise intensities and volumes could be elicited during cycling on EAB's. In this study we examined, for the first time, the acute physiological impact of electrical support during outdoor cycling in CAD patients (ISRCTN32238279).

    Methods: Fifteen CAD patients (13 males), aged 64 ± 7 years executed a maximal cardiopulmonary exercise test and afterwards cycled a predefined outdoor route of 10 km, in three different conditions: classical cycling (no support), EAB with low support (EABlow) and high support (EABhigh). Read More

    Obstructive sleep apnoea: from respiratory events to coronary microvascular dysfunction.
    Acta Cardiol 2017 Oct 9:1-6. Epub 2017 Oct 9.
    a Department of Cardiology , University Hospital of Montpellier , Montpellier , France.
    Obstructive sleep apnoea (OSA) is an emerging and independent risk factor for cardiovascular diseases; coronary artery disease (CAD) is higher in OSA patients, even in the absence of other traditional cardiovascular risk factors. There is little evidence to show abnormalities in coronary blood flow (CBF) and disorders in coronary vascular resistance (CVR), occurring during the obstructive respiratory event, suggesting coronary microvascular dysfunction (CMD) as a potential mechanism of ischaemic heart disease (IHD) OSA-as a related consequence. Read More

    Three-dimensional transoesophageal echocardiography is crucial for valid assessment of mitral valve leaflet morphology in severe mitral regurgitation prior to interventional repair.
    Acta Cardiol 2017 Oct 5:1-9. Epub 2017 Oct 5.
    a Technische Universität Dresden, Heart Center Dresden University Hospital , Dresden , Germany.
    Background: Interventional mitral valve (MV) repair of severe symptomatic mitral regurgitation (MR) is a therapeutic option in high-risk surgical or inoperable patients. Assessment of the MV remains a crucial part of pre-interventional screening. Three-dimensional transoesophageal echocardiography (3D-TOE) may compensate for well-known pitfalls that occur in 2D-TOE. Read More

    Coagulation F13A1 V34L, fibrinogen and homocysteine versus conventional risk factors in the pathogenesis of MI in young persons.
    Acta Cardiol 2017 Oct 5:1-7. Epub 2017 Oct 5.
    c Department of Cardiology , Postgraduate Institute of Medical Education and Research , Chandigarh , India.
    Background: The pathogenesis of myocardial infarction (MI) involves environmental and genetic risk factors, with the latter putatively playing significant roles in younger patients. Genetic variability in coagulation factors comprises one such group. The coagulation factor 13 subunit A (F13A1) Val34Leu polymorphism (rs5985) has yielded variable findings in literature, with no prior South Asian data. Read More

    Loop diuretic down-titration in stable chronic heart failure is often achievable, especially when urinary chloride concentration is low.
    Acta Cardiol 2017 Oct 3:1-7. Epub 2017 Oct 3.
    a Department of Cardiology , Ziekenhuis Oost-Limburg , Genk , Belgium.
    Background: This study investigates spot urinary chloride concentration in euvolemic chronic heart failure (CHF) patients.

    Methods: This prospective cohort study included 50 ambulatory CHF patients on maintenance loop diuretics without recent hospital admission, clinical signs of volume overload, or adjustment in neurohumoral blocker or diuretic therapy. Spot urinary samples were collected immediately after loop diuretic intake. Read More

    Long-term outcomes of bioresorbable vascular scaffold in ST-elevation myocardial infarction.
    Acta Cardiol 2017 Sep 28:1-6. Epub 2017 Sep 28.
    a Department of Medicine , Montreal Heart Institute, Université de Montréal , Montreal , Canada.
    Background: Bioresorbable vascular scaffolds (BVS) implantation in selected patients with stable angina has been demonstrated feasible and safe. However, limited data are currently available on long-term outcomes after BVS implantation for ST-elevation myocardial infarction (STEMI). Therefore, we sought to assess the safety, efficacy and long-term results of BVS implantation in STEMI patients. Read More

    Prognostic value of sST2 and NT-proBNP at admission in heart failure with preserved, mid-ranged and reduced ejection fraction.
    Acta Cardiol 2017 Sep 25:1-8. Epub 2017 Sep 25.
    b Department of Cardiology , Tianjin Union Medical Center, Nankai University Affiliated Hospital , Tianjin , P.R. China.
    Objective: The aim of this study was to compare sST2 at admission with N-terminal pro B-type natriuretic peptide (NT-proBNP) in prognostic accuracy among different types of heart failure (HF) and clarifying the enhanced prognostic value in patients with HF by the combination of the two biomarkers.

    Methods And Results: A total of 164 consecutive patients admitted to our institution for HF were divided into three groups of HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction (HFmrEF) and HF with preserved ejection fraction (HFpEF). Circulating sST2 and NT-proBNP were measured using the enzyme-linked immunosorbent assay (ELISA). Read More

    Serum paraoxonase activity in patients with ischaemic and nonischaemic dilated cardiomyopathy.
    Acta Cardiol 2017 Sep 12:1-6. Epub 2017 Sep 12.
    a Department of Cardiology, Faculty of Medicine , Uludag University , Bursa , Turkey.
    Background: This study examined whether the serum PON1 activity is different in patients with ischaemic dilated cardiomyopathy (IDCM) and nonischaemic dilated cardiomyopathy (NDCM) and the relation between the serum PON1 activity and serum pro-BNP levels.

    Methods And Results: In this study, we enrolled 60 patients with left ventricular systolic failure (New York Heart Association [NYHA] class III-IV) and a left ventricular ejection fraction (EF) < 40% as determined by echocardiography and 30 healthy subjects. The patients with systolic heart failure were divided into two groups: patients with IDCM and patients with NDCM. Read More

    Hemorheological dysfunction in cardiac syndrome X.
    Acta Cardiol 2017 Sep 11:1-9. Epub 2017 Sep 11.
    a Faculty of Medicine, Department of Physiology , Pamukkale University , Kinikli , Denizli, Turkey.
    Background: Cardiac syndrome X (CSX) is often described as angina or angina-like chest pain with a normal coronary arteriogram, yet the underlying pathophysiological mechanisms have not been fully elucidated. The aim of the current study was to determine alterations in blood rheology (erythrocyte aggregation and deformability, plasma viscosity - PV) in patients with CSX.

    Methods: The study comprised 26 CSX patients (55. Read More

    Rosuvastatin inhibits high glucose-stimulated upregulation of VCAM-1 via the MAPK-signalling pathway in endothelial cells.
    Acta Cardiol 2017 Sep 8:1-6. Epub 2017 Sep 8.
    b Department of Medicine , Catholic Kwandong University College of Medicine , Gangneung , Republic of Korea.
    Objective: The aim of this study is to investigate the molecular mechanisms and effect of rosuvastatin on adhesion molecule induction in human endothelial cells under high-glucose conditions (HG).

    Methods And Results: The effects of rosuvastatin on vascular cell adhesion molecule (VCAM)-1 production and pERK phosphorylation were measured in HG-induced human umbilical vein endothelial cells (HUVECs) with inhibitors targeting the mitogen-activated protein kinase (MAPK) signal pathway. HG increased levels of VCAM-1. Read More

    Predictors of a high defibrillation threshold test during routine ICD implantation.
    Acta Cardiol 2017 Sep 8:1-7. Epub 2017 Sep 8.
    a Department of Cardiology , University Hospitals Leuven , Leuven , Belgium.
    Background: There is growing evidence that routine defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantation is not necessary. However a small group of patients might be at risk if no DFT testing is performed.

    Methods: Patients with a new pectoral ICD implantation in our hospital between 2006 and 2014 were included in a retrospective registry. Read More

    Increased monocyte-to-HDL cholesterol ratio is related to cardiac syndrome X.
    Acta Cardiol 2017 Oct 30;72(5):516-521. Epub 2017 Aug 30.
    a Department of Cardiology , Dumlupinar University School of Medicine , Kutahya , Turkey.
    Objective: Cardiac syndrome X (CSX) is typically identified with ischaemia in treadmill exercise test or stress myocardial perfusion scintigraphy as well as angina-like chest pain without stenosis in coronary angiography. The purpose of the present study is to investigate the association between cardiac syndrome X and monocyte-to-HDL cholesterol ratio (MHR) which is a new marker associated with inflammation.

    Patients And Methods: A total of 230 patients (105 patients with cardiac syndrome X and 125 normal controls) were included in the study. Read More

    Comparison of radial access versus femoral access with the use of a vascular closure device for the prevention of vascular complications and mortality after percutaneous coronary intervention.
    Acta Cardiol 2017 Aug 29:1-7. Epub 2017 Aug 29.
    a Department of Cardiology , Antwerp University Hospital , Antwerp , Belgium.
    Background: Radial access (RA) and vascular closure devices (VCD) have been shown to be superior to transfemoral access (TFA) with regard to the prevention of vascular complications after percutaneous coronary intervention (PCI).

    Objective: The present study evaluates whether RA is associated with less vascular complications and a lower mortality than VCD.

    Methods: A total of 6999 consecutive PCI patients were studied through a single-centre prospective registry from January 2011 to August 2015. Read More

    Left ventricular assist device: exercise capacity evolution and rehabilitation added value.
    Acta Cardiol 2017 Aug 28:1-8. Epub 2017 Aug 28.
    c Department of Cardiac Surgery , Erasme Hospital , Brussels , Belgium.
    Background: With more than 15,000 implanted patients worldwide and a survival rate of 80% at 1-year and 59% at 5-years, left ventricular assist device (LVAD) implantation has become an interesting strategy in the management of heart failure patients who are resistant to other kinds of treatment. There are limited data in the literature on the change over time of exercise capacity in LVAD patients, as well as limited knowledge about the beneficial effects that rehabilitation might have on these patients. Therefore, the aim of our study was to evaluate the evolution of exercise capacity on a cohort of patients implanted with the same device (HeartWare(©)) and to analyse the potential impact of rehabilitation. Read More

    Moderate, but not vigorous, intensity exercise training reduces C-reactive protein.
    Acta Cardiol 2017 Aug 28:1-8. Epub 2017 Aug 28.
    b Department of Kinesiology , The University of Georgia , Athens , GA , USA.
    Background: Sprint interval cycle training is a contemporary popular mode of training but its relative efficacy, under conditions of matched energy expenditure, to reduce risk factors for cardiometabolic disease is incompletely characterised, especially in young women. The purpose of this investigation was to determine the relative efficacy of six weeks of moderate-intensity cycling (MOD-C) and vigorous sprint-interval cycling (VIG-SIC) on lipid profile, insulin (INS) and insulin resistance using the homeostatic model assessment (HOMA-IR) and C-reactive protein (CRP) in inactive, overweight/obese (OW/OB) young women.

    Methods: Participants (BMI ≥25 kg/m(2), waist circumference ≥88 cm) were randomly assigned to MOD-C (20-30 min at 60-70% of heart rate reserve(HRR)) or VIG-SIC (5-7 repeated bouts 30-second maximal effort sprints, followed by four minutes of active recovery) supervised training three days/week for six weeks, with each group matched on energy expenditure. Read More

    Plasma osteopontin concentration is elevated in patients with coronary bare metal stent restenosis.
    Acta Cardiol 2017 Aug 25:1-6. Epub 2017 Aug 25.
    a Cardiology Department, Faculty of Medicine , Baskent University , Ankara , Turkey.
    Objective: Osteopontin is a component of atherosclerotic lesions, secreted by monocytes, macrophages and endothelial and vascular smooth muscle cells, which together are responsible for neointimal proliferation. We examined whether elevated plasma osteopontin concentration was associated with in-stent restenosis in patients with coronary artery disease.

    Subjects And Methods: We enrolled 91 patients who underwent coronary artery stenting, and 60 control patients with normal findings on coronary angiography, between June 2012 and September 2013. Read More

    Diagnostic efficacy of fractional flow reserve with coronary angiography in dual-source computed tomography scanner.
    Acta Cardiol 2017 Aug 22:1-8. Epub 2017 Aug 22.
    c Department of Cardiovascular , Shaanxi Provincial People's Hospital , Xi'an , Shaanxi , China.
    Objective: The management of patients with intermediate coronary lesions is a major clinical issue. Fractional flow reserve (FFR) is considered the gold criterion for the assessment of ischaemic stenosis, but it requires an invasive procedure. Coronary computed tomography angiography (CTA) for fractional flow reserve (FFRCT) is a novel noninvasive alternative for the diagnosis of ischaemic lesions. Read More

    Prosthetic valve endocarditis: positron emission tomography/computed tomography as a new golden grail.
    Acta Cardiol 2017 Aug 22:1-6. Epub 2017 Aug 22.
    c Department of Cardiology , Viecuri Medical Center , Venlo , The Netherlands.
    Prosthetic valve endocarditis (PVE) is a serious infection with potentially fatal consequences. Early detection is crucial for successful management and outcome. The diagnosis of PVE is challenging and is based on the Duke criteria (DC) in which echocardiography plays a crucial role. Read More

    Change of plasmalogen content of red blood cells in myocardial hypoxia and acidosis.
    Acta Cardiol 2017 Aug 17:1-8. Epub 2017 Aug 17.
    a Central Educational and Research Laboratory , Mogilev State A. Kuleshov University , Mogilev , Belarus.
    Background: The contribution of hypoxic conditions to the chemical composition of membranes is not completely established. Plasmalogens, containing an alkenyl group with aldehydogenic ether linkage, are significant components of membrane lipids and their level can change in oxygen deficiency.

    Methods: Analysis of plasmalogens in red blood cells was performed in patients (n = 17) with coronary heart disease, stable angina (functional class II-III) and coronary atherosclerosis. Read More

    Transcatheter aortic valve implantation compared with surgical aortic valve replacement in patients with anaemia.
    Acta Cardiol 2017 Aug 16:1-10. Epub 2017 Aug 16.
    a Centre for Global Health, Istituto Superiore di Sanità , Rome , Italy.
    Objectives: We compared the outcome of anaemic patients undergoing transcatheter (TAVI) and surgical aortic valve replacement (SAVR) for severe aortic valve stenosis.

    Methods: Anaemic patients (haemoglobin <13.0 g/dL in men and <12. Read More

    Protocol-driven remote monitoring of cardiac resynchronization therapy as part of a heart failure disease management strategy.
    Acta Cardiol 2017 Aug 14:1-10. Epub 2017 Aug 14.
    a Department of Cardiology , Ziekenhuis Oost-Limburg , Genk , Belgium.
    Background: Cardiac resynchronisation therapy (CRT) is an established treatment for heart failure (HF) with reduced ejection fraction. CRT devices are equipped with remote monitoring functions, which are pivotal in the detection of device problems, but may also facilitate disease management. The aim of this study was to provide a comprehensive overview of the clinical interventions taken based on remote monitoring. Read More

    Economic and social impact of increased cardiac rehabilitation uptake and cardiac telerehabilitation in Belgium - a cost-benefit analysis.
    Acta Cardiol 2017 Aug 11:1-8. Epub 2017 Aug 11.
    a Department of Cardiology , Jessa Hospital , Hasselt , Belgium.
    Background: Cardiac rehabilitation for ischaemic heart disease effectively reduces cardiovascular readmission rate and mortality. Current uptake rates however, remain low. This study assesses the social and economic impact of increasing centre-based cardiac rehabilitation uptake and the additional value of cardiac telerehabilitation using cost-benefit analysis (CBA) in Belgium. Read More

    Syncope: current knowledge, uncertainties and strategies for management optimisation in the emergency department.
    Acta Cardiol 2017 Aug 11:1-7. Epub 2017 Aug 11.
    a Department of Emergency , Academic Hospital of Parma , Parma , Italy.
    Admission rates and expenditures for syncope remain high. This unsatisfactory management could be due to several factors, including lack of evidence-based strategy, poor accuracy of clinical decision rules, difficulty in disseminating guidelines, as well as uncertainties concerning management of intermediate-risk patients and role of observation protocols and syncope units. To optimise management, it has been proposed to adopt a pragmatic, symptoms-based definition of syncope and a classification related to the underlying mechanism rather than suspected aetiology. Read More

    The impact of the latest echocardiographic chamber quantification recommendations on the prediction of left atrial appendage thrombus presence by transthoracic echocardiography.
    Acta Cardiol 2017 Aug 11:1-5. Epub 2017 Aug 11.
    a Chair and Department of Cardiology , Medical University of Lodz , Lodz , Poland.
    Introduction: The latest recommendations for echocardiographic chamber quantification have implemented updated normal values for all cardiac chambers.

    Purpose: To evaluate the incidence of normal and abnormal values of routine echocardiographic parameters such as left ventricular ejection fraction (LVEF) and left atrial volume indexed to body surface area (LAVi) in patients with non-valvular atrial fibrillation (AF) and to determine the influence of LVEF and LAVi reclassification on the prediction of LAAT by transthoracic echocardiography.

    Methods: We retrospectively analysed the database of 1674 transesophageal echocardiograms performed between 2012 and 2015 in our echo lab. Read More

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