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    4392 results match your criteria Acta cardiologica[Journal]

    1 OF 88

    Serum paraoxonase activity in patients with ischaemic and nonischaemic dilated cardiomyopathy.
    Acta Cardiol 2017 Sep 12:1-6. Epub 2017 Sep 12.
    a Department of Cardiology, Faculty of Medicine , Uludag University , Bursa , Turkey.
    Background: This study examined whether the serum PON1 activity is different in patients with ischaemic dilated cardiomyopathy (IDCM) and nonischaemic dilated cardiomyopathy (NDCM) and the relation between the serum PON1 activity and serum pro-BNP levels.

    Methods And Results: In this study, we enrolled 60 patients with left ventricular systolic failure (New York Heart Association [NYHA] class III-IV) and a left ventricular ejection fraction (EF) < 40% as determined by echocardiography and 30 healthy subjects. The patients with systolic heart failure were divided into two groups: patients with IDCM and patients with NDCM. Read More

    Hemorheological dysfunction in cardiac syndrome X.
    Acta Cardiol 2017 Sep 11:1-9. Epub 2017 Sep 11.
    a Faculty of Medicine, Department of Physiology , Pamukkale University , Kinikli , Denizli, Turkey.
    Background: Cardiac syndrome X (CSX) is often described as angina or angina-like chest pain with a normal coronary arteriogram, yet the underlying pathophysiological mechanisms have not been fully elucidated. The aim of the current study was to determine alterations in blood rheology (erythrocyte aggregation and deformability, plasma viscosity - PV) in patients with CSX.

    Methods: The study comprised 26 CSX patients (55. Read More

    Rosuvastatin inhibits high glucose-stimulated upregulation of VCAM-1 via the MAPK-signalling pathway in endothelial cells.
    Acta Cardiol 2017 Sep 8:1-6. Epub 2017 Sep 8.
    b Department of Medicine , Catholic Kwandong University College of Medicine , Gangneung , Republic of Korea.
    Objective: The aim of this study is to investigate the molecular mechanisms and effect of rosuvastatin on adhesion molecule induction in human endothelial cells under high-glucose conditions (HG).

    Methods And Results: The effects of rosuvastatin on vascular cell adhesion molecule (VCAM)-1 production and pERK phosphorylation were measured in HG-induced human umbilical vein endothelial cells (HUVECs) with inhibitors targeting the mitogen-activated protein kinase (MAPK) signal pathway. HG increased levels of VCAM-1. Read More

    Predictors of a high defibrillation threshold test during routine ICD implantation.
    Acta Cardiol 2017 Sep 8:1-7. Epub 2017 Sep 8.
    a Department of Cardiology , University Hospitals Leuven , Leuven , Belgium.
    Background: There is growing evidence that routine defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantation is not necessary. However a small group of patients might be at risk if no DFT testing is performed.

    Methods: Patients with a new pectoral ICD implantation in our hospital between 2006 and 2014 were included in a retrospective registry. Read More

    Increased monocyte-to-HDL cholesterol ratio is related to cardiac syndrome X.
    Acta Cardiol 2017 Aug 30:1-6. Epub 2017 Aug 30.
    a Department of Cardiology , Dumlupinar University School of Medicine , Kutahya , Turkey.
    Objective: Cardiac syndrome X (CSX) is typically identified with ischaemia in treadmill exercise test or stress myocardial perfusion scintigraphy as well as angina-like chest pain without stenosis in coronary angiography. The purpose of the present study is to investigate the association between cardiac syndrome X and monocyte-to-HDL cholesterol ratio (MHR) which is a new marker associated with inflammation.

    Patients And Methods: A total of 230 patients (105 patients with cardiac syndrome X and 125 normal controls) were included in the study. Read More

    Comparison of radial access versus femoral access with the use of a vascular closure device for the prevention of vascular complications and mortality after percutaneous coronary intervention.
    Acta Cardiol 2017 Aug 29:1-7. Epub 2017 Aug 29.
    a Department of Cardiology , Antwerp University Hospital , Antwerp , Belgium.
    Background: Radial access (RA) and vascular closure devices (VCD) have been shown to be superior to transfemoral access (TFA) with regard to the prevention of vascular complications after percutaneous coronary intervention (PCI).

    Objective: The present study evaluates whether RA is associated with less vascular complications and a lower mortality than VCD.

    Methods: A total of 6999 consecutive PCI patients were studied through a single-centre prospective registry from January 2011 to August 2015. Read More

    Left ventricular assist device: exercise capacity evolution and rehabilitation added value.
    Acta Cardiol 2017 Aug 28:1-8. Epub 2017 Aug 28.
    c Department of Cardiac Surgery , Erasme Hospital , Brussels , Belgium.
    Background: With more than 15,000 implanted patients worldwide and a survival rate of 80% at 1-year and 59% at 5-years, left ventricular assist device (LVAD) implantation has become an interesting strategy in the management of heart failure patients who are resistant to other kinds of treatment. There are limited data in the literature on the change over time of exercise capacity in LVAD patients, as well as limited knowledge about the beneficial effects that rehabilitation might have on these patients. Therefore, the aim of our study was to evaluate the evolution of exercise capacity on a cohort of patients implanted with the same device (HeartWare(©)) and to analyse the potential impact of rehabilitation. Read More

    Moderate, but not vigorous, intensity exercise training reduces C-reactive protein.
    Acta Cardiol 2017 Aug 28:1-8. Epub 2017 Aug 28.
    b Department of Kinesiology , The University of Georgia , Athens , GA , USA.
    Background: Sprint interval cycle training is a contemporary popular mode of training but its relative efficacy, under conditions of matched energy expenditure, to reduce risk factors for cardiometabolic disease is incompletely characterised, especially in young women. The purpose of this investigation was to determine the relative efficacy of six weeks of moderate-intensity cycling (MOD-C) and vigorous sprint-interval cycling (VIG-SIC) on lipid profile, insulin (INS) and insulin resistance using the homeostatic model assessment (HOMA-IR) and C-reactive protein (CRP) in inactive, overweight/obese (OW/OB) young women.

    Methods: Participants (BMI ≥25 kg/m(2), waist circumference ≥88 cm) were randomly assigned to MOD-C (20-30 min at 60-70% of heart rate reserve(HRR)) or VIG-SIC (5-7 repeated bouts 30-second maximal effort sprints, followed by four minutes of active recovery) supervised training three days/week for six weeks, with each group matched on energy expenditure. Read More

    Plasma osteopontin concentration is elevated in patients with coronary bare metal stent restenosis.
    Acta Cardiol 2017 Aug 25:1-6. Epub 2017 Aug 25.
    a Cardiology Department, Faculty of Medicine , Baskent University , Ankara , Turkey.
    Objective: Osteopontin is a component of atherosclerotic lesions, secreted by monocytes, macrophages and endothelial and vascular smooth muscle cells, which together are responsible for neointimal proliferation. We examined whether elevated plasma osteopontin concentration was associated with in-stent restenosis in patients with coronary artery disease.

    Subjects And Methods: We enrolled 91 patients who underwent coronary artery stenting, and 60 control patients with normal findings on coronary angiography, between June 2012 and September 2013. Read More

    Diagnostic efficacy of fractional flow reserve with coronary angiography in dual-source computed tomography scanner.
    Acta Cardiol 2017 Aug 22:1-8. Epub 2017 Aug 22.
    c Department of Cardiovascular , Shaanxi Provincial People's Hospital , Xi'an , Shaanxi , China.
    Objective: The management of patients with intermediate coronary lesions is a major clinical issue. Fractional flow reserve (FFR) is considered the gold criterion for the assessment of ischaemic stenosis, but it requires an invasive procedure. Coronary computed tomography angiography (CTA) for fractional flow reserve (FFRCT) is a novel noninvasive alternative for the diagnosis of ischaemic lesions. Read More

    Prosthetic valve endocarditis: positron emission tomography/computed tomography as a new golden grail.
    Acta Cardiol 2017 Aug 22:1-6. Epub 2017 Aug 22.
    c Department of Cardiology , Viecuri Medical Center , Venlo , The Netherlands.
    Prosthetic valve endocarditis (PVE) is a serious infection with potentially fatal consequences. Early detection is crucial for successful management and outcome. The diagnosis of PVE is challenging and is based on the Duke criteria (DC) in which echocardiography plays a crucial role. Read More

    Change of plasmalogen content of red blood cells in myocardial hypoxia and acidosis.
    Acta Cardiol 2017 Aug 17:1-8. Epub 2017 Aug 17.
    a Central Educational and Research Laboratory , Mogilev State A. Kuleshov University , Mogilev , Belarus.
    Background: The contribution of hypoxic conditions to the chemical composition of membranes is not completely established. Plasmalogens, containing an alkenyl group with aldehydogenic ether linkage, are significant components of membrane lipids and their level can change in oxygen deficiency.

    Methods: Analysis of plasmalogens in red blood cells was performed in patients (n = 17) with coronary heart disease, stable angina (functional class II-III) and coronary atherosclerosis. Read More

    Transcatheter aortic valve implantation compared with surgical aortic valve replacement in patients with anaemia.
    Acta Cardiol 2017 Aug 16:1-10. Epub 2017 Aug 16.
    a Centre for Global Health, Istituto Superiore di Sanità , Rome , Italy.
    Objectives: We compared the outcome of anaemic patients undergoing transcatheter (TAVI) and surgical aortic valve replacement (SAVR) for severe aortic valve stenosis.

    Methods: Anaemic patients (haemoglobin <13.0 g/dL in men and <12. Read More

    Protocol-driven remote monitoring of cardiac resynchronization therapy as part of a heart failure disease management strategy.
    Acta Cardiol 2017 Aug 14:1-10. Epub 2017 Aug 14.
    a Department of Cardiology , Ziekenhuis Oost-Limburg , Genk , Belgium.
    Background: Cardiac resynchronisation therapy (CRT) is an established treatment for heart failure (HF) with reduced ejection fraction. CRT devices are equipped with remote monitoring functions, which are pivotal in the detection of device problems, but may also facilitate disease management. The aim of this study was to provide a comprehensive overview of the clinical interventions taken based on remote monitoring. Read More

    Economic and social impact of increased cardiac rehabilitation uptake and cardiac telerehabilitation in Belgium - a cost-benefit analysis.
    Acta Cardiol 2017 Aug 11:1-8. Epub 2017 Aug 11.
    a Department of Cardiology , Jessa Hospital , Hasselt , Belgium.
    Background: Cardiac rehabilitation for ischaemic heart disease effectively reduces cardiovascular readmission rate and mortality. Current uptake rates however, remain low. This study assesses the social and economic impact of increasing centre-based cardiac rehabilitation uptake and the additional value of cardiac telerehabilitation using cost-benefit analysis (CBA) in Belgium. Read More

    Syncope: current knowledge, uncertainties and strategies for management optimisation in the emergency department.
    Acta Cardiol 2017 Aug 11:1-7. Epub 2017 Aug 11.
    a Department of Emergency , Academic Hospital of Parma , Parma , Italy.
    Admission rates and expenditures for syncope remain high. This unsatisfactory management could be due to several factors, including lack of evidence-based strategy, poor accuracy of clinical decision rules, difficulty in disseminating guidelines, as well as uncertainties concerning management of intermediate-risk patients and role of observation protocols and syncope units. To optimise management, it has been proposed to adopt a pragmatic, symptoms-based definition of syncope and a classification related to the underlying mechanism rather than suspected aetiology. Read More

    The impact of the latest echocardiographic chamber quantification recommendations on the prediction of left atrial appendage thrombus presence by transthoracic echocardiography.
    Acta Cardiol 2017 Aug 11:1-5. Epub 2017 Aug 11.
    a Chair and Department of Cardiology , Medical University of Lodz , Lodz , Poland.
    Introduction: The latest recommendations for echocardiographic chamber quantification have implemented updated normal values for all cardiac chambers.

    Purpose: To evaluate the incidence of normal and abnormal values of routine echocardiographic parameters such as left ventricular ejection fraction (LVEF) and left atrial volume indexed to body surface area (LAVi) in patients with non-valvular atrial fibrillation (AF) and to determine the influence of LVEF and LAVi reclassification on the prediction of LAAT by transthoracic echocardiography.

    Methods: We retrospectively analysed the database of 1674 transesophageal echocardiograms performed between 2012 and 2015 in our echo lab. Read More

    A higher volume of fibrotic tissue on virtual histology prior to coronary stent implantation predisposes to more pronounced neointima proliferation.
    Acta Cardiol 2017 Aug 11:1-8. Epub 2017 Aug 11.
    a The Department of Cardiology , Antwerp University Hospital , Edegem , Belgium.
    Background: Since neointima smooth muscle cells (SMC) mainly originate from the vessel wall, we investigated whether atherosclerotic plaque composition influences subsequent in-stent neointima proliferation and restenosis.

    Methods: We performed intravascular ultrasound (IVUS) with virtual histology in 98 patients prior to elective bare-metal stent (BMS) implantation in de novo coronary artery lesions. Virtual histology variables pre-percutaneous coronary intervention (PCI) were related to in-stent neointima proliferation six months after implantation assessed as late luminal loss of 0. Read More

    A simple discharge risk model for predicting 1-year mortality in hospitalised acute decompansated heart failure patients with reduced ejection fraction.
    Acta Cardiol 2017 Aug 8:1-7. Epub 2017 Aug 8.
    a Department of Cardiology , Kocaeli University Medical Faculty , Kocaeli , Turkey.
    Objective: The risk stratification for prognosis in heart failure is very important for optimal disease management and decision making. The aim of this study was to establish a simple discharge 1-year mortality prediction model by integrating data obtained from demographic characteristics, clinical evaluation, laboratory biomarkers and echocardiographic evaluation of hospitalised heart failure with reduced ejection fraction (HFrEF) patients with acute decompensation.

    Methods And Results: A risk score model was developed based on β-coefficient number of variables in a multivariable logistic regression model which was created with the use of data on clinical, laboratory, imaging and therapeutic findings of 670 patients (65. Read More

    Association of MIR-499a expression and seed region variant (rs3746444) with cardiovascular disease in Egyptian patients.
    Acta Cardiol 2017 Aug 8:1-10. Epub 2017 Aug 8.
    f Department of Cardiology, Faculty of Medicine , Suez Canal University , Ismailia , Egypt.
    Background: Circulating microRNAs could be powerful markers of acute myocardial infarction (MI) and its functional genetic variants could increase susceptibility to cardiovascular disease (CVD). The current study aimed to quantify the microRNA (miR)-499a levels in serum of MI patients compared to hypertensive and healthy subjects and to investigate the association of its A/G variant rs3746444 with CVD in a sample of an Egyptian population.

    Methods: Serum miR-499a relative expressions were measured in 110 acute MI patients, 76 hypertensive patients, and 121 healthy controls by Real-time quantitative polymerase chain reaction. Read More

    The strength of the multivariable associations of major risk factors predicting coronary heart disease mortality is homogeneous across different areas of the Seven Countries Study during 50-year follow-up.
    Acta Cardiol 2017 Aug 8:1-7. Epub 2017 Aug 8.
    f Department of Epidemiology, University Medical Center Groningen , University of Groningen and Division of Human Nutrition, Wageningen University , The Netherlands.
    Objectives: To compare the magnitude of multivariable coefficients and hazard ratios of four cardiovascular risk factors across five worldwide regions of the Seven Countries Study in predicting 50-year coronary deaths.

    Material And Methods: A total of 13 cohorts of middle-aged men at entry (40-59 years old) were enrolled in the mid-1900s from five relatively homogeneous groups of cohorts (areas): USA, Finland and Zutphen - the Netherlands, Italy and Greece, Serbia, Japan for a total of 10,368 middle-aged men. The major risk factors measured at baseline were age, number of cigarettes smoked, systolic blood pressure and serum cholesterol. Read More

    Predictive value of exercise-induced atrial natriuretic peptide secretion for the presence of left atrial low-voltage areas in patients with persistent atrial fibrillation.
    Acta Cardiol 2017 Aug;72(4):433-439
    a Department of Cardiology , First Affiliated Hospital of Nanchang University , Nanchang City , China.
    Objectives Left atrial (LA) low-voltage areas (LVAs) are a strong predictor of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). However, a non-invasive method for evaluating LA-LAVs has not been established yet. The objective of our study was to assess the predictive value of the plasma atrial natriuretic peptide (ANP) level for the presence of LA-LVAs in patients with persistent AF (PeAF). Read More

    The feasibility of substituting left atrial wall strain for flow velocity of left atrial appendage.
    Acta Cardiol 2017 Jul 28:1-6. Epub 2017 Jul 28.
    b Department of Cardiovascular Medicine , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama , Japan.
    Objective: Non-valvular atrial fibrillation (NVAF) is frequently complicated by thromboembolism. Left atrial appendage (LAA) flow is a predictor of LAA thrombosis. LAA flow is measured by transesophageal echocardiography (TEE), which is a semi-invasive diagnostic tool. Read More

    Sudden unexplained cardiac deaths in young adults: a call for multidisciplinary approach.
    Acta Cardiol 2017 Jul 26:1-6. Epub 2017 Jul 26.
    a Third Department of Cardiology , SMDZ in Zabrze, Medical University of Silesia, Silesian Center for Heart Disease , Zabrze , Poland.
    The investigation of death in young (<35 years), previously fit individuals, calls for a detailed autopsy with emphasis placed upon the examination of the heart. In most instances, the cause of cardiac death can be identified during autopsy. However, a large percentage of sudden deaths remain unexplained even after comprehensive medicolegal investigation, including autopsy, and are labelled as autopsy-negative sudden unexplained cardiac death (SUD). Read More

    Comparison of the long-term reproducibility of the walk test and of exercise peak oxygen consumption in patients with preserved exercise capacity.
    Acta Cardiol 2017 Jul 26:1-8. Epub 2017 Jul 26.
    b Pôle d'Activité Médico-Chirurgicale Cardio-vasculaire, Unité de Soins Intensifs de Cardiologie , Hôpitaux Universitaires de Strasbourg , Strasbourg Cedex , France.
    Short-term and long-term reproducibility of the cardiopulmonary (CPX) exercise test have been established. Though short and mid-term reproducibility of the walk test has been ascertained, this was not extensively done for the long-term reproducibility. The aim of the study was to examine the long-term reproducibility of distance walked in an allotted time and to check the stability of the relationship between walked distance and exercise peak VO2 (pVO2). Read More

    Giant left circumflex coronary artery aneurysm with fistula to the right atrium.
    Acta Cardiol 2017 Jul 26:1-2. Epub 2017 Jul 26.
    a Hartcentrum ZNA , Middelheim Hospital , Antwerp , Belgium.
    Coronary artery fistulae are rare cardiac anomalies with a prevalence of 0.2% of all the patients undergoing coronary angiography. The majority of them are congenital and generally origin from the right coronary artery. Read More

    Dysfunction of the foetal arterial duct results in a wide spectrum of cardiovascular pathology.
    Acta Cardiol 2017 Jul 26:1-11. Epub 2017 Jul 26.
    a Department of Fetal and Pediatric Cardiology , University Hospitals Leuven , Leuven , Belgium.
    Objective: Foetal ductal problems may have various cardiopulmonary consequences. This study aimed to identify the spectrum of ductus arteriosus (DA) dysfunction (closure, constriction, kinking, aneurysm and thrombosis) and the resultant clinical and echocardiographic presentation in foetuses and neonates.

    Methods And Results: This is a retrospective analysis of serial pre- and post-natal data of 27 cases of foetal ductal dysfunction diagnosed at a median gestational age of 33 weeks (range 20-39). Read More

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