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Acta Biomater 2022 May 21. Epub 2022 May 21.

Chair of Solid Mechanics, University of Wuppertal, 42119 Wuppertal, Germany; Wuppertal Center for Smart Materials & Systems, University of Wuppertal, 42119 Wuppertal, Germany. Electronic address:

Nacre's superior mechanical properties and failure behavior strongly depend on orientation due to its brick-and-mortar microstructure. In this work, the anisotropic microscopic deformation and the resulting macroscopic mechanical properties are evaluated under different loading conditions. Our in situ transmission electron microscopy deformation experiments and finite element simulations reveal that nacre possesses enhanced indentation resistance along the direction normal to the tablets through delocalization of indentation-induced deformation by taking advantage of its layered structure. Read More

Acta Biomater 2022 May 21. Epub 2022 May 21.

Centre for Research in Nano Technology and Science, Indian Institute of Technology Bombay, Mumbai, India; Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Bombay, Mumbai, India,. Electronic address:

The versatility of ZnO quantum dots (QDs) exhibiting size-tunable visible photoluminescence has propelled them to the forefront of leading-edge innovations in healthcare. At the nano-bio interface, enhancing the singly-ionized oxygen vacancy defects (V) through holistic, sustainable synthesis protocols driven by the synergistic influence of QDs' nucleation-growth kinetics has implications on their bioactivity, physiochemical, and optical performance. Recently, robust continuous flow platforms have transcended the conventional batch reactors by alleviating the concerns of "hot-spot" formation due to inhomogeneous heat distribution, acute energy consumption, poor quality, and yield. Read More

Clin Chim Acta 2022 May 21. Epub 2022 May 21.

University of Antwerp, Faculty of Medicine and Health Sciences, Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.

The basophil activation test (BAT)has emerged as a reliable complementary diagnostic to document IgE-dependent allergies and to study cross-reactivity between structural homologues. However, the BAT has some weaknesses that hinder a wider application. The BAT requires fresh blood samples and is lost as a diagnostic in patients showing a non-responder status of their cells. Read More

Clin Chim Acta 2022 May 21. Epub 2022 May 21.

Department of Emergency Medicine, Ali Asghar children hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Infancy and early childhood are the most common ages for acute pyretic Kawasaki disease (KD). Although the etiology remains a mystery, the current concept is that KD is caused by a contagious pathogen that infects the genetically vulnerable and induces an inflammatory mechanism aimed at cardiovascular organs. Resolving the inflammatory process and decreasing the incidence of coronary anomalies, namely coronary aneurysms, are two benefits of high-dose intravenous immunoglobulin (IVIG) administration. Read More

Acta Trop 2022 May 21:106536. Epub 2022 May 21.

Department of Biosciences and Pediatric Clinical Research Center "Romeo ed Enrica Invernizzi", University of Milan, 20133, Milan, Italy; Italian Malaria Network, Inter University Center for Malaria Research, University of Milan, 20133, Milan, Italy. Electronic address:

In the last decade, Aedes koreicus and Aedes japonicus japonicus mosquitoes, which are competent vectors for various arboviruses of public health relevance, colonised Italy and other European countries. Nevertheless, information about their current and potential distribution is partial. Accordingly, in this study four regions of Northern Italy (Lombardy, Liguria, Piedmont and Aosta Valley) were surveyed during 2021 for the presence of eggs, larvae and pupae of these two invasive species. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 18;279:121400. Epub 2022 May 18.

Faculty of Science, Chemistry Department, Zagazig University, Zagazig 44519, Egypt. Electronic address:

Spectrophotometry was used to determine trace amounts of Zirconium(IV), Mercury(II) and Uranium(VI) in environmental, biological, pharmaceutical and industrial samples. The determination depend on the complexation reactions between albendazole reagent and metal ions [Zr(IV), Hg(II) and U(VI)] at 555 nm, 485 nm and 510 nm, respectively. The experimental conditions were explored to reach the optimum conditions for albendazole-metal ions interaction, including detection of a suitable wavelength, medium (pH), reagent concentration, surfactants effect, reaction time and temperature. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 18;279:121399. Epub 2022 May 18.

School of Control Engineering, Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China; College of Information Science and Engineering, Northeastern University, Shenyang 110819, China. Electronic address:

A miniature luminol chemiluminescence system based on atmosphere microplasma is proposed for detection without any catalysts. In our research, atmosphere microplasma jet is employed to oxidize luminol and produce chemiluminescence instead of HO. The transport of OH radicals to the plasma-liquid interface and induce the chemiluminescence. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 11;279:121370. Epub 2022 May 11.

Centre for Optical and Electromagnetic Research, National Engineering Research Center for Optical Instruments, Zhejiang Provincial Key Laboratory for Sensing Technologies, Zhejiang University, Hangzhou 310058, China. Electronic address:

A portable short-wavelength infrared microscope hyperspectral imager (SMHI) combined with machine learning algorithms for the purpose of classifying geographical origins as well as root types of Lindera aggregata is developed. The spectral range of the SMHI system is 1090-1820 nm (5500-9100 cm-1) with spectral and spatial resolutions of 4 nm and 27.3 μm, respectively. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 11;279:121369. Epub 2022 May 11.

Kweichow Moutai Group, Renhuai, Guizhou 564501, China. Electronic address:

Accurate and effective discrimination of E. coli and Shigella is an important clinical issue, and there are many limitations in traditional methods of analysis. FT-IR shows great potential in the classification of bacteria with high specificity and low cost. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 16;279:121350. Epub 2022 May 16.

College of Artificial Intelligence, Nankai University, Tianjin 300350, China.

Salmon and Cod are economically significant world-class fish that have high economic value. It is difficult to accurately sort and process them by appearance during harvest and transportation. Conventional chemical detection means are time-consuming and costly, which greatly affects the cost and efficiency of Fishery production. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2022 May 18;279:121404. Epub 2022 May 18.

Faculty of Chemistry, Warsaw University of Technology, 3 Noakowskiego Str., 00-664 Warsaw, Poland.

Heat-treated succinite modified under air, oxygen or inert gas atmosphere to improve its colour and clarity, was studied with Fourier-Transform Infrared and Raman spectroscopy, and referenced to variously altered untreated samples. For treated amber, the macroscopic observations revealed diagnostic features such as (1) the presence of discoidal " sun sparkles" inside the crumbs; (2) unusual colours (e.g. Read More

Acta Odontol Scand 2022 May 24:1-11. Epub 2022 May 24.

Faculty of Health Sciences, School of Medicine, Institute of Dentistry, University of Eastern Finland, Kuopio, Finland.

Objectives: The paper reports the demographic characteristics of patients with lichenoid lesions affecting only the upper labial mucosa, with or without associated lesions in the maxillary anterior gingiva, alongside the lesions' clinical and histopathological features, treatment, follow-up and prognosis. Also, a new case with lengthy follow-up is presented.

Materials And Methods: A systematic review was performed in line with PRISMA guidelines. Read More

Acta Paediatr 2022 May 24. Epub 2022 May 24.

Federal Medical Centre, Asaba, Delta State, Nigeria.

Aim: Critically review research methods used to elicit children and young people's views and experiences in the first year of COVID-19, using an ethical and child rights lens.

Methods: Systematic search of peer-reviewed literature on children and young people's perspectives and experiences of COVID-19. LEGEND (Let Evidence Guide Every New Decision) tools were applied to assess the quality of included studies. Read More

Acta Neuropathol 2022 May 24. Epub 2022 May 24.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY, 10032, USA.

Alzheimer's disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction between CVRFs and genetic variants might explain the pathogenesis. Genome-wide, gene by CVRF interaction analyses for AD, in 6568 patients and 8101 controls identified FMNL2 (p = 6. Read More

Mikrochim Acta 2022 May 24;189(6):227. Epub 2022 May 24.

Department of Entomology & Nematology, UC Davis Comprehensive Cancer Center, University of California, Davis, CA, 95616, USA.

Acta Paediatr 2022 May 24. Epub 2022 May 24.

Neonatal Intensive Care Unit, Grenoble Alpes University Hospital, 38000, Grenoble, France.

Aim: This single-centre French cohort study evaluated the relationship between standardized assessment at 2 years of corrected age and schooling level at 5 years of age in children born at ≤ 32 weeks' gestational age.

Methods: This was a single-centre retrospective study of children born preterm between 2010 and 2014 included in a follow-up network. At 5 years of age, the population was divided into 2 groups: (1) "appropriate schooling", defined as age-appropriate schooling without support, and (2) "schooling with support". Read More

Acta Paediatr 2022 May 24. Epub 2022 May 24.

Regional Rehabilitation Centre Queen Silvia Children´s Hospital, Sahlgrenska University Hospital, Gothenburg.

Aim: The aim of this scoping review was to summarise findings concerning cognitive characteristics in people with spina bifida and explain how cognitive factors influence activities and participation in different areas and stages of life.

Methods: PubMed, Psych INFO, ERIC, Scopus, CINAHL and the Cochrane Library were searched for English language papers published in 2000-2018. A total of 92 papers were selected and quality assessed according to the McMaster criteria. Read More

Acta Cardiol 2022 May 24:1-2. Epub 2022 May 24.

Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Acta Paediatr 2022 May 24. Epub 2022 May 24.

Neonatal Services, The Royal Women's Hospital, Melbourne, Victoria, Australia.

Acta Oncol 2022 May 24:1-9. Epub 2022 May 24.

Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

Background: Exercise during oncological treatment is beneficial to patient health and can counteract the side effects of treatment. Knowledge of the societal costs associated with an exercise intervention, however, is limited. The aims of the present study were to evaluate the long-term resource utilisation and societal costs of an exercise intervention conducted during (neo)adjuvant oncological treatment in a randomised control trial (RCT) versus usual care (UC), and to compare high-intensity (HI) versus low-to-moderate intensity (LMI) exercise in the RCT. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):590-592

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):463-473

NORAD is a newly identified long non-coding RNA (lncRNA) that plays an important role in cancers. NORAD has been found to be highly expressed in the mouse model of acute myocardial infarction (AMI). However, the role of NORAD in the regulation of AMI remains unknown. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):537-547

Engineering Research Center of Glycoconjugates Ministry of Education, Jilin Provincial Key Laboratory of Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China.

Glucosylsucroses are potentially useful as additives in cosmetic and pharmaceutical formulations. Although enzymatic synthesis of glucosylsucroses is the most efficient method for their production, the key enzyme that produces them has remained unknown. Here, we report that glucosylsucrose synthase from (TeGSS) catalyzes the synthesis of glucosylsucrose using sucrose and UDP-glucose as substrates. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):583-586

Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):548-555

Perioperative hyperglycemia is a common metabolic disorder in the clinic. Hyperglycemia, via upregulation of E74-like ETS transcription factor 3 (ELF3), induces cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) expressions, thus leading to endothelial apoptosis and vascular endothelial injury. Propofol is a widely used anesthetic. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):587-589

Department of Endocrinology, Gongli Hospital, the Second Military Medical University, Shanghai 200135, China.

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):452-462

The Affiliated Nanhua Hospital, Department of Anus and Bowels, Hengyang Medical School, University of South China, Hengyang 421001, China.

The long non-coding RNA (lncRNA) forebrain embryonic zinc finger protein 1 antisense RNA1 (FEZF1-AS1) was recently identified as an oncogenic gene in several types of tumors. The biological function of FEZF1-AS1 in rectal cancer progression, however, remains unknown. In the present study, we discover that FEZF1-AS1 is significantly upregulated in rectal cancer tissues and cells. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):524-536

Accumulating evidence indicates that ER-phagy serves as a key adaptive regulatory mechanism in response to various stress conditions. However, the exact mechanisms underlying ER-phagy in the pathogenesis of intervertebral disc degeneration remain largely unclear. In the present study, we demonstrated that RETREG1-mediated ER-phagy is induced by glucose deprivation (GD) treatment, along with ER stress activation and cell function decline. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):415-451

Shenzhen Key Laboratory of Steroid Drug Discovery and Development, School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China.

Hyperglycemia in diabetic patients is associated with abnormally-elevated cellular glucose levels. It is hypothesized that increased cellular glucose will lead to increased formation of endogenous methanol and/or formaldehyde, both of which are then metabolically converted to formic acid. These one-carbon metabolites are known to be present naturally in humans, and their levels are increased under diabetic conditions. Read More

Acta Biochim Biophys Sin (Shanghai) 2022 Apr;54(4):494-503

Adipose tissue formation and moderate fat deposition are important for the production performance and eating quality of livestock meats. The self-renewal and adipogenic differentiation of adipose-derived stem cells are responsible for the formation and development of adipose tissue. In addition, estrogen targeting G protein-coupled estrogen receptor 1 (GPER1) has been reported to modulate cell proliferation and differentiation during tissue and organ development. Read More