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Acta Reumatol Port 2021 Oct-Dec;46(4):372-373

Serviço de Reumatologia, Hospital Garcia de Orta.

Acta Reumatol Port 2021 Oct-Dec;46(4):370-371

Serviço de Radiologia, Centro Hospitalar Universitário São João, Porto, Portugal.

Acta Reumatol Port 2021 Oct-Dec;46(4):368-369

Serviço de Reumatologia, Hospital de Egas Moniz.

Acta Reumatol Port 2021 Oct-Dec;46(4):365-367

Serviço de Reumatologia, Centro Hospitalar do Baixo Vouga.

Systemic lupus erythematosus (SLE) is an autoimmune disease with potential multisystemic involvement. Mesenteric panniculitis (MP) has been described as a rare feature in patients with SLE. The authors present a case of a 26 years old patient with previous diagnosis of SLE presenting with abdominal pain and distension and a peri-umbilical mass. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):363-364

Serviço de Reumatologia, Hospital Garcia de Orta.

Acta Reumatol Port 2021 Oct-Dec;46(4):360-362

Serviço de Ortopedia e Traumatologia, Centro Hospitalar Lisboa Norte EPE - Hospital de Santa Maria.

Bone marrow edema syndrome is a rare disease with an unknown etiology, self-limited and usually associated with an indolent course, which can also generate severe pain with tremendous functional impairment. The authors present a case of a 19-year-old female patient with a progressive, non-traumatic and unrelentless pain involving both knees, requiring persistently walking aids and analgesic drugs. The imaging studies showed a bilateral distal femur and proximal tibia bone marrow edema in the magnetic resonance imaging. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):342-349

CEDOC, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal; Centro Hospitalar de Lisboa Ocidental, Hospital de Egas Moniz, Lisboa, Rheumatology Department, Portugal.

Background: Axial Spondyloarthritis (axSpA) is a chronic, inflammatory rheumatic disease that affects the axial skeleton, causing pain, stiffness, and fatigue. Genetics and environmental factors such as microbiota and microtrauma are known causes of disease susceptibility and progression. Murine models of axSpA found a decisive role for biomechanical stress as an inducer of enthesitis and new bone formation. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):333-341

Serviço de Reumatologia, Hospital de Santa Maria, Centro Hospitalar Universitário de Lisboa Norte, Lisboa, Portugal; Unidade de Investigação Reumatologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade Medicina Universidade de Lisboa.

Psoriatic disease (Psoriasis and Psoriatic Arthritis, PsD) is a condition that affects the skin, the musculoskeletal system, and beyond, impairing patients' quality of life. A multidisciplinary approach of combined dermatology-rheumatology clinics is recommended and valuable to respond to PsD diagnosis, management, and treatment challenges. In Portugal, five Hospitals have implemented a multidisciplinary clinic for PsD assessment. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):328-332

Serviço de Ortopedia da Unidade Local de Saúde de Matosinhos.

Introduction: Fragility fractures cause significant mortality and morbidity. Even though there are multiple guidelines for the management of fragility fractures, european countries still report treatment rates of less than 30%. Implementation of fracture liaison services can increase this percentage by 21%. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):317-327

Rheumatology Service at Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León.

Objective: The classification and/or diagnosis of Primary Sjögren's Syndrome (PSS) requires a multidimensional approach. Although age and the duration of sicca symptoms can affect the clinical, serological and histological features found at initial evaluation, these are not considered when using classification criteria as a guide for PSS diagnosis. Our study aimed to explore if there is any relationship between the duration of symptoms and clinical, histopathological and serological findings. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):297-316

Department of Internal Medicine, Celal Bayer University.

Aims: Ankylosing spondylitis (AS) reduces spinal mobility, which results in structural and functional impairments. Pulmonary problems eventually occur in most AS patients due to interstitial lung disease or as a result of chest wall abnormalities. The aim of this study was to evaluate the effects on pulmonary functions and disease related scales of aquatic and land-based multidimensional functional mobility exercises on pulmonary functions in patients with AS. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):295-296

Head of Rheumatology Department - Egas Moniz Hospital, Lisboa Ocidental Hospital Centre (HEM,CHLO-EPE); Full Professor and Dean of NOVA Medical School, NOVA University Lisbon (NMS/UNL); Principal Investigator - Comprehensive Health Research Center (CHRC).

Acta Reumatol Port 2021 Oct-Dec;46(4):355-359

Serviço de Medicina I, Clínica Universitária de Medicina I, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte.

Granulocyte colony-stimulating factor (G-CSF) is increasingly being used to prevent febrile neutropenia associated with chemotherapy. Large-vessel vasculitis (LVV) has been recognized as a rare side effect of G-CSF treatment. We report a case of G-CSF associated LVV in a patient with breast cancer. Read More

Acta Reumatol Port 2021 Oct-Dec;46(4):350-354

Serviço de Reumatologia, Hospital Garcia de Orta; Instituto de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa.

Granulomatous with polyangiitis (GPA) is a necrotizing granulomatous vasculitis that mostly affects small-sized vessels. The disease can affect many organs, although renal and respiratory tract involvement are the most frequent and distinguishing features. Musculoskeletal manifestations have been reported in about 50% of patients and can occur as myalgia, oligoarthralgia/arthritis of large joints or polyarthralgia/arthritis of small joints. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):283-285

Rheumatology, Centro Hospitalar Universitário São João.

Introduction: Long-term survivors of cystic fibrosis (CF) have a dramatic increase in the risk of osteoporosis and incident fracture. The objective of this work is to characterize a CF related bone disease in a Portuguese cohort of CF patients.

Methods: We performed a cross-sectional, observational study on a cohort of CF adult patients. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):281-282

Reumatologia, Centro Hospitalar Universitário de S.João, Porto.

This is the first detailed description of an erosive seronegative polyarthritis in the Vogt-Koyanagi-Harada Syndrome in Portugal. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):277-278

Orthopedics and Traumatology, Castelo Branco Local Health Unit.

Acta Reumatol Port 2021 Jul-Sep;46(3):279-280

Rheumatology Department, Centro Hospitalar e Universitário de Coimbra.

Acta Reumatol Port 2021 Jul-Sep;46(3):266-271

Rheumatology, Centro Hospitalar Universitário São João.

Tumor necrosis factor alpha inhibitors (TNFi) are basilar treatments in a number of inflammatory rheumatic conditions and autoimmune phenomena such as de novo neuroinflammatory events were already described in these populations under TNFi. We conducted a single-center retrospective study in a cohort of rheumatic patients treated with TNFi to characterize neurological demyelinating/inflammatory disease in these patients. We report 3 cases (n= 744): all of them had spondyloarthritis, the onset of neurological manifestations occurred between 37 and 58 years old and all of them initially presented with an optic neuritis. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):257-265

Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Portugal

Systemic sclerosis (SSc) is an uncommon condition, with a wide range of manifestations, characterized by specific antibody production, vasculopathy and fibrosis of the skin and other internal organs. It is a complex disease, which is estimated to be rare in Portugal, although specific incidence data are missing. The aetiology of SSc remains unknown, but is likely to be multifactorial, involving genetic and environmental aspects. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):252-256

Serviço de Reumatologia - Centro Hospitalar Baixo Vouga.

Purpose: COVID-19 changed the dynamics of all healthcare system, leading to the restructuring of inpatient teams as well as the emergency department. Scheduled surgeries were suspended, operating rooms were closed, and anesthesiologists redistributed among the various intensive care units. At the Centro Hospitalar do Baixo Vouga the number of patients admitted to the emergency department decreased to approximately 8. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):230-238

Rheumatology Department, Hospital de Braga.

Background: Axial Spondyloarthritis (axSpA) refers to a group of rheumatic diseases that mainly affect the axial skeleton. Treatment with Biological Disease Modifying Anti-Rheumatic Drug (bDMARDs) is indicated when low disease activity is not achieved with Non-Steroid Anti-inflammatory Drugs. Certain clinical and socio-demographic features may be predictive of future need for treatment with bDMARDs in a patient with axSpA. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):239-245

Orthopaedic Surgery, Kyushu University.

Aims: Few reports have focused on the distal interphalangeal (DIP) joint in patients with rheumatoid arthritis (RA). The purposes of this study were to evaluate the frequency of bone erosion of the DIP joint, and to determine the factors associated with its deformity.

Methods: This study reviewed 204 patients with RA in whom radiographs of hands were obtained. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):272-276

Serviço de Medicina Interna, Centro Hospitalar de Vila Nova de Gaia/Espinho.

Introduction: IgG4-related disease (IgG4-RD) is characterized by the growth of pseudotumors, which can affect almost every organ. Elevated serum IgG4 levels are present in only two-thirds of the patients and are not specific. Diagnosis is difficult and is usually based on a biopsy. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):208-217

EpiDoc Unit, CEDOC; Comprehensive Health Research Centre; Reumatologia/ NOVA Medical School, Lisboa; CHLO, Hospital Egas Moniz, Lisboa.

Background: Hand osteoarthritis (HOA) is a highly prevalent rheumatic disease that predominates in females and causes pain and loss of functional capacity. Obesity and metabolic syndrome have been previously suggested to associate with the severity of HOA, but clarity on these associations is yet to be achieved.

Objective: Test the association between obesity and other components of the metabolic syndrome and disability in women with hand osteoarthritis (HOA). Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):218-229

CHRC - Comprehensive Health Research Center, CEDOC, NOVA Medical School; Rheumatology Department, CHLO, EPE - Centro Hospitalar de Lisboa Ocidental, Hospital de Egas Moniz, Lisboa.

Objective: Biobanks for research (BBR) have enormous value for research, including those specifically oriented to chronic diseases. Knowing public attitudes and perceptions is key to design and implement patient-centered BBR. We assessed patient awareness, perception and choices among rheumatology outpatients regarding aging biobanking activities. Read More

Acta Reumatol Port 2021 Jul-Sep;46(3):205-207

Portuguese Institute of Rheumatology and Lisbon Rheumatology Clinic.

Acta Reumatol Port 2021 Apr-Jun;46(2):186-188

Pediatric and Young Adult Rheumatology Unity, Centro Hospitalar Universitário São João, Porto, Portugal.

We report a case of Trichorhinophalangeal syndrome type I (TRPS1) in a 16-year-old boy who was referred due to painless finger deformities over the last year. Legg-Calvé-Perthes disease (LGP) had been diagnosed at age 7 and required surgical treatment at age 12. Parents were healthy and non consanguineous; there was family history of pectus carinatum of maternal lineage. Read More

Acta Reumatol Port 2021 Apr-Jun;46(2):189-190

Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Heraklion, Greece.

Acta Reumatol Port 2021 Apr-Jun;46(2):171-176

Serviço de Ortopedia e Traumatologia, Centro Hospitalar Lisboa Norte, EPE; Hospital de Santa Maria.

We present the case of a 32-year-old man with a diagnosis of type-III osteogenesis imperfecta who developed a telangiectatic osteosarcoma in the proximal right tibia. An above-knee amputation was performed and after one-year follow-up, pulmonary metastatic lesions were detected on the thoracic CT scan. Palliative chemotherapy was proposed and to date the patient is still living and is under medical treatment. Read More