649,988 results match your criteria Acta Radiologica [Journal]


Hemophagocytic Lymphohistiocytosis during the Postpartum Stage of Pregnancy: A Report of Eight Cases.

Acta Haematol 2018 Dec 7;141(1):55-60. Epub 2018 Dec 7.

Haemophagocytic lymphohistiocytosis (HLH) is a rare and severe clinical syndrome that can be classified as either primary or secondary. Secondary HLH can be triggered by a variety of diseases. Pregnancy-related HLH has already been observed clinically. Read More

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December 2018

Postpartum Hemophagocytic Lymphohystiocytosis: A New Entity Is Born.

Acta Haematol 2018 Dec 7;141(1):61-62. Epub 2018 Dec 7.

Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel.

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December 2018

Formation mechanisms of Caprolactam-tetraalkyl ammonium halide deep eutectic and its hydrate.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 5;211:189-194. Epub 2018 Dec 5.

School of Environmental Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, Hebei, 050018, China; Pollution prevention biotechnology laboratory of Hebei Province, 050018, China. Electronic address:

Deep eutectic solvents (DES) are generally composed of two or three cheap and safe components that are associated with each other via hydrogen bonds. The formation Caprolactam (CPL)-tetraalkyl ammonium halide (TAAX) DES and its hydrate were investigated using React IR. TAAX was introduced to CPL in the molten state at 353. Read More

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December 2018

A multifunctional sensor for selective and sensitive detection of vitamin B12 and tartrazine by Förster resonance energy transfer.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 4;211:178-188. Epub 2018 Dec 4.

Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong 637002, China; Institute of Applied Chemistry, China West Normal University, Nanchong 637002, China. Electronic address:

We used thiamine nitrate (TN) as single material to fabricate nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) with a quantum yield of 10.4% through one-pot hydrothermal method, and its properties were characterized by TEM, XPS, FTIR, fluorescence (FL) and UV-vis spectrophotometer, respectively. The fluorescence of N,S-CQDs was effectively quenched in the presence of vitamin B12 (VB12)/tartrazine due to Förster resonance energy transfer (FRET). Read More

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December 2018

Measurements and correlations in solution-state for charge transfer products caused from the 1:2 complexation of TCNE acceptor with several important drugs.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 5;211:166-177. Epub 2018 Dec 5.

Department of Chemistry, Faculty of Science, Taif University, Al-Haweiah, P.O. Box 888, 21974 Taif, Saudi Arabia; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.

In our previous work, we highlighted the thermodynamic and spectroscopic characteristics of the 1:1 charge transfer (CT) complexation of TCNE acceptor with various medically important drugs. Continuing that work, we further examine drugs that react with the TCNE acceptor via a 1:2 interaction. The examined drugs are atenolol, quinidine, cimetidine, reserpine, and levofloxacin. Read More

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December 2018

The synthesis of Ag-coated tetrapod gold nanostars and the improvement of surface-enhanced Raman scattering.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 4;211:154-165. Epub 2018 Dec 4.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. Electronic address:

In this work, the novel tetrapod gold nanostars with four specific numbers of sharp tips were synthesized with good uniformity, high yield and chemical stability. The size of tetrapod gold nanostars has been increased effectively by increasing the amount of HAuCl or DEA added to the reaction solution, and the corresponding in-plane localized surface plasmon resonance (LSPR) band can shift from 700 to 1100 nm. In order to combine the advantages of different metals, the Ag-coated tetrapod gold nanostars were prepared with different Ag coating thicknesses by increasing the volume of AgNO. Read More

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December 2018

Topological design, permeability and mechanical behavior of additively manufactured functionally graded porous metallic biomaterials.

Acta Biomater 2018 Dec 8. Epub 2018 Dec 8.

Department of Biomechanical Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.

Recent advances in additive manufacturing (AM) have enabled the fabrication of functionally graded porous biomaterials (FGPBs) for application as orthopedic implants and bone substitutes. Here, we present a step-wise topological design of FGPB based on diamond unit cells to mimic the structure of the femoral diaphysis. The FGPB was manufactured from Ti-6Al-4V powder using the selective laser melting (SLM) technique. Read More

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December 2018
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Development of an in house ELISA for human intact osteocalcin and its utility in diagnosis and management of osteoporosis.

Clin Chim Acta 2018 Dec 8. Epub 2018 Dec 8.

Department of Molecular Immunodiagnostics, ICMR-National Institute for Research In Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai, India. Electronic address:

Background: Serum Osteocalcin (OC) is a biomarker for evaluating bone turnover in humans. Commercial kits of OC in India are imported, hence expensive prohibiting their use in routine screening of osteoporosis. The present study describes the development, validation of human OC ELISA and establishes cut off values for its use in screening and management of women at risk for osteoporosis. Read More

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December 2018
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Efficiency of excitation energy trapping in the green photosynthetic bacterium Chlorobaculum tepidum.

Biochim Biophys Acta Bioenerg 2018 Dec 8. Epub 2018 Dec 8.

Laboratory of Biophysics, Wageningen University, Wageningen, the Netherlands; MicroSpectroscopy Research Facility, Wageningen University, Wageningen, the Netherlands. Electronic address:

During the millions of years of evolution, photosynthetic organisms have adapted to almost all terrestrial and aquatic habitats, although some environments are obviously more suitable for photosynthesis than others. Photosynthetic organisms living in low-light conditions require on the one hand a large light-harvesting apparatus to absorb as many photons as possible. On the other hand, the excitation trapping time scales with the size of the light-harvesting system, and the longer the distance over which the formed excitations have to be transferred, the larger the probability to lose excitations. Read More

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December 2018

High versus low dose caffeine in preterm infants.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.

We are grateful to Vliegenthart et al for their letter (1) commenting on our systematic review, which compared the use of high versus low dose caffeine in preterm infants (2). A clear definition of the inclusion criteria in a systematic review is an essential step to minimise the risk of intellectual bias. Vliegenthart et al state that pooling the results of the studies they identified did not affect the estimate of the effect size of the outcome of bronchopulmonary dysplasia. Read More

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December 2018

Models.

Acta Physiol (Oxf) 2018 Dec 7:e13237. Epub 2018 Dec 7.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Vegetative Physiology.

A look at the history of science supports this statement. Harvey's discovery of the blood circulation, published in 1628, is undoubtedly among the most important events in the history of physiology. Although Harvey's concept of blood circulation was brilliant at that time, it was far away from a comprehensive insight into the circulatory system. Read More

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December 2018

Relationship between retinal vessel diameter with both retinal nerve fibre layer thickness and optic nerve head parameters in middle-aged Caucasians: the Northern Finland Birth Cohort Eye study.

Acta Ophthalmol 2018 Dec 10. Epub 2018 Dec 10.

Department of Ophthalmology, Oulu University Hospital, Oulu, Finland.

Purpose: To study the normal relationship between retinal vessel diameter (RVD) with retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) parameters in a cohort of middle-aged Caucasians.

Methods: We investigated 3070 individuals (6140 eyes). Central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) were measured in the right eye using a semi-automated computer-assisted program. Read More

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December 2018
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Providing very preterm infants with donor human milk led to faster breastfeeding rates but worse biometric gains.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Neonatology, Puerta de Hierro Majadahonda University Hospital, Madrid.

Aim: To evaluate the immediate clinical impact of donor human milk availability in a NICU about nutritional, clinical and biometric parameters.

Methods: This retrospective-cohort study included 28-32 weeks gestational age born at our hospital in a three-year period before and after the donor human milk implementation. Data about starting, advance and discharge enteral nutrition, clinical outcomes, hospital stay and biometrics, was collected. Read More

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December 2018

Review shows that thyroid hormone substitution could benefit transient hypothyroxinaemia of prematurity but treatment strategies need to be clarified.

Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.

Department of Neonatology, University Hospitals Leuven, KU, Leuven, Belgium.

Aim: Thyroid hormones are crucial for fetal and neonatal brain development. This paper provides an overview of the normal role of thyroid hormones in fetal brain development and the pathophysiology of transient hypothyroxinaemia of prematurity (THOP). It also discusses the diagnostic and therapeutic controversies around THOP and looks at directions for future research. Read More

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December 2018

Corrigendum.

Authors:

Acta Paediatr 2019 Jan;108(1):190

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January 2019

Highlights in this issue.

Acta Paediatr 2019 Jan;108(1):6-7

Acta Paediatrica, Stockholm, Sweden.

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January 2019

Acknowledgements.

Authors:

Acta Paediatr 2019 Jan;108(1):185-189

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January 2019

Probiotics can stimulate initial head growth in premature infants.

Authors:
Olivier Claris

Acta Paediatr 2019 Jan;108(1):10-11

Department of Neonatology, Hospices Civils de Lyon, Hôpital Femme Mère Enfants, Claude Bernard University, Lyon, France.

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January 2019

A meta-analysis of neurodevelopmental outcomes at 4-10 years in children born at 22-25 weeks gestation.

Acta Paediatr 2018 Dec 10. Epub 2018 Dec 10.

University of Ottawa, Faculty of Medicine, Ottawa, Canada.

Aim: To update our meta-analysis on neurodevelopmental disability rates in children born at 22-25 weeks gestation. The main outcome measure was rates of neurodevelopmental disability in survivors at age 4-10 years.

Methods: We used a peer-reviewed electronic and grey search to identify articles. Read More

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December 2018

Opioids are rarely prescribed for children with acute non-procedural pain in Italian emergency departments.

Acta Paediatr 2018 Dec 8. Epub 2018 Dec 8.

Director of Paediatric Pain and Palliative Care Service, Department of Women's and Children's Health, University Hospital, Padua, Italy.

Pain is a major cause of admissions to pediatric emergency departments, but is often inappropriately managed (1). The findings of the Pain Practice in Italian Pediatric Emergency Departments on the appropriate use of paracetamol and ibuprofen have previously been reported (1,2). This multicentre, retrospective study evaluated the prescription of opioids given to patients up to the age of 14 with acute non-procedural pain by 18 Italian emergency departments between October 2014 and January 2015. Read More

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December 2018

Six-minute screening test can provide valid information about the skills that underlie childhood reading and cognitive abilities.

Acta Paediatr 2018 Dec 9. Epub 2018 Dec 9.

Educational Neuroimaging Center, Faculty of Education in Science and Technology, Technion, Haifa, Israel.

Aim: Reading difficulties can have complex origins and diagnostic measures can be expensive and time consuming. We tested Zippy6, a six-minute screening test that we developed, to see how it compared with a battery of established screening tools.

Methods: This study was carried out at Cincinnati Children's Hospital Medical Center, USA, from 2014-2016. Read More

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December 2018

Mechanical loading releases osteoclastogenesis-modulating factors through stimulation of the P2X7 receptor in hematopoietic progenitor cells.

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Clinical and Experimental Medicine, Division of Cell Biology, Linköping University, Linköping, Sweden.

Mechanical instability of bone implants stimulate osteoclast differentiation and peri-implant bone loss, leading to prosthetic loosening. It is unclear which cells at the periprosthetic interface transduce mechanical signals into a biochemical response, and subsequently facilitate bone loss. We hypothesized that mechanical overloading of hematopoietic bone marrow progenitor cells, which are located near to the inserted bone implants, stimulates the release of osteoclast-inducing soluble factors. Read More

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December 2018

Practice variation among Dutch paediatricians in palivizumab prescription rates: the importance of parental counselling approach.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Paediatrics, Isala, Zwolle.

Aim: To investigate differences in palivizumab prescription rates between Dutch paediatricians, and the role of parent counselling in this practice variation.

Methods: A retrospective chart review of premature infants <32 weeks of gestation, aged
Results: We included 208 patients, 133 (64%) of whom received palivizumab. Read More

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December 2018

Infants who die in shared sleeping situations differ from those who die while sleeping alone.

Acta Paediatr 2018 Dec 10. Epub 2018 Dec 10.

Discipline of Anatomy and Pathology, Adelaide Medical School, The University of Adelaide, Adelaide, Australia.

Aim: To determine whether there are differences between infants who are sharing a sleeping surface with others, compared to those who die alone.

Methods: A literature review was undertaken of pubmed and google scholar databases using search terms: sudden infant death syndrome, SIDS, cosleeping and overlaying.

Results: Statistically significant differences were found between the two groups in the sex ratios, and in staining of brain sections for β-amyloid precursor protein (β-APP), glial fibrillary acidic protein (GFAP) and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling (TUNEL). Read More

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December 2018

Fasting insulin resistance affects the prevalence of metabolically healthy obesity in Brazilian adolescents.

Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.

Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Aim: We aimed to assess the influence of fasting insulin resistance on metabolically healthy obesity (MHO) prevalence in adolescents and to identify associated factors.

Methods: This retrospective, registry-based, cross-sectional study included 418 (51.9% girls) 10-18 year-old adolescents with obesity from a tertiary outpatient clinic in Sao Paulo, Brazil, between 2009 and 2013. Read More

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December 2018
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Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.

Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.

Inserm, UMR1153, Centre de Recherche en Épidémiologie et Statistique Sorbonne Paris Cité (CRESS), équipe Épidémiologie Périnatale, Obstétricale et Pédiatrique (ÉPOPé) Labex GR-Ex, Paris, France.

Sacri A-S, de Lauzon-Guillain B, Dufourg M-D, Bois C, Charles M A, Chalumeau M. Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.

Aim: To study the rate of iron-fortified infant formula (IFF) use in young children in France and its association with socioeconomic factors. Read More

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December 2018

Novel compound heterozygous FATP4 mutations caused ichthyosis prematurity syndrome in Spanish sisters.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Fundación Pública Galega de Medicina Xenómica-SERGAS, CIBERER, IDIS, Grupo de Medicina Xenómica-Universidade de Santiago de Compostela, Santiago de CompostelaSpain.

Ichthyosis prematurity syndrome (IPS), or ichthyosis congenita type IV, is a rare syndromic form of autosomic recessive ichthyosis caused by mutations in fatty acid transport protein 4 (FATP4), also known as SLC27A4. Patients with a disrupted FATP4 gene are usually born prematurely with thick desquamating skin and other complications, such as neonatal asphyxia, eosinophilia and elevated serum immunoglobulin E levels. Symptoms become less severe after the first months of life, evolving to non-scaly ichthyosis with follicular hyperkeratosis in adulthood (1, 2). Read More

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December 2018
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Vitreous Wiping, a new technique for removal of vitreous cortex remnants during vitrectomy.

Acta Ophthalmol 2018 Dec 7. Epub 2018 Dec 7.

Department of Vitreoretinal Surgery, The Rotterdam Eye Hospital, Rotterdam, the Netherlands.

Purpose: Unremoved vitreoschisis-induced vitreous cortex remnants (VCR) are associated with macular pathology. When present on the retinal periphery, they may play a role in proliferative vitreoretinopathy and retinal detachment after vitrectomy. Existing instruments for their removal involve substantial risk of iatrogenic retinal damage. Read More

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December 2018

Model that predicted death or disabilities in premature infants was valid at seven years of age.

Acta Paediatr 2018 Dec 8. Epub 2018 Dec 8.

Neonatologist. 12 de Octubre University Hospital, Madrid, Spain.

Aim: Validated a model that used bronchopulmonary dysplasia (BPD), brain injuries measured using ultrasound and retinopathy of prematurity (ROP) to predict late death or disability in premature infants at seven years of age.

Methods: A retrospective study was performed at the 12 de Octubre Hospital neonatal unit in Madrid. A logistic model was applied to estimate the independent prognostic contribution of each morbidity and the effect that the combination of morbidities had on the seven-year outcomes. Read More

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December 2018

Intrathecal betamethasone for cancer pain: A study of its analgesic efficacy and safety.

Acta Anaesthesiol Scand 2018 Dec 7. Epub 2018 Dec 7.

Department of Anesthesiology, Kansai Medical University Medical Center, Moriguchi, Japan.

Background: A preliminary study has shown effective cancer pain relief by intrathecal betamethasone (ITB). However, further evidence is needed to support this new approach.

Methods: Cancer patients with opioid-resistant pain received lumbar intrathecal administration of betamethasone 2 or 3 mg once a week for 28 days. Read More

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December 2018
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A survey demonstrates limited palliative care structures in paediatric nephrology from the perspective of a multidisciplinary healthcare team.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Paediatric Gastroenterology, Nephrology and Metabolic Diseases, Charité - Universitätsmedizin Berlin, Germany.

Aim: Children and adolescents with end stage renal disease face a high morbidity and mortality. Palliative care provides a multidisciplinary approach to reduce disease burden and improve quality of life. This study evaluated concepts and current structures of palliative care from the perspective of a multidisciplinary paediatric nephrology team including physicians, nurses and psychosocial health professionals. Read More

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December 2018

Digital stethoscopes in paediatric medicine.

Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatrics, Monash University, Melbourne, Australia.

Aim: To explore, synthesise and discuss currently available digital stethoscopes (DS) and the evidence for their use in paediatric medicine.

Methods: Systematic review and narrative synthesis of digital stethoscope use in paediatrics following searches of OVID Medline, Embase, Scopus, PubMed and Google Scholar databases.

Results: Six digital stethoscope makes were identified to have been used in paediatric focused studies so far. Read More

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December 2018

Heart involvement in patients with myotonic dystrophy type 2.

Acta Neurol Belg 2018 Dec 7. Epub 2018 Dec 7.

Neurology Clinic, Clinical Centre of Serbia, School of Medicine, University of Belgrade, 6, Dr Subotica Street, Belgrade, 11000, Serbia.

Myotonic dystrophy type 2 (DM2) is a slowly progressive, autosomal-dominant disease. This is a multisystemic disorder that affects the heart, which is one of the main causes of morbidity and mortality in DM2. The aim of the study was to define cardiac impairments in patients with DM2 and its association with sociodemographic and clinical features of patients. Read More

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December 2018

A triazine based organic framework with micropores and mesopores for use in headspace solid phase microextraction of phthalate esters.

Mikrochim Acta 2018 Dec 7;186(1). Epub 2018 Dec 7.

College of Chemistry, Jilin University, Changchun, 130012, China.

A dual-pore covalent organic framework (COF) that contains micropores and mesopores was prepared from 2,4,6-triphenoxy-1,3,5-triazine (TPT). A building block is used in which double linking sites were introduced at each branch of a C-symmetric skeleton. The COF is shown to be a viable coating for fibers for solid-phase microextraction of phthalic acid esters (PAEs). Read More

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December 2018

The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments.

Acta Neuropathol 2018 Dec 7. Epub 2018 Dec 7.

Wicking Dementia Research and Education Centre, College of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.

This review recounts the definitions and research evidence supporting the multifaceted roles of neuroinflammation in the injured brain following trauma. We summarise the literature fluctuating from the protective and detrimental properties that cytokines, leukocytes and glial cells play in the acute and chronic stages of TBI, including the intrinsic factors that influence cytokine responses and microglial functions relative to genetics, sex, and age. We elaborate on the pros and cons that cytokines, chemokines, and microglia play in brain repair, specifically neurogenesis, and how such conflicting roles may be harnessed therapeutically to sustain the survival of new neurons. Read More

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December 2018

A phenylboronate-based SERS nanoprobe for detection and imaging of intracellular peroxynitrite.

Mikrochim Acta 2018 Dec 10;186(1):11. Epub 2018 Dec 10.

Key Laboratory for Advanced Materials, Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

A surface-enhanced Raman scattering (SERS) based nanoprobe was developed for detection and imaging of endogenous peroxynitrite in living cells. The probe was fabricated by assembling 3-mercaptophenylboronic acid pinacol ester onto the surface of gold nanoparticles (AuNPs). The detection of peroxynitrite is accomplished via measurement of the changes in the SERS spectra (at 882 cm) that are caused by the reaction between probe and peroxynitrite. Read More

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December 2018

Amperometric sensing of nitrite at nanomolar concentrations by using carboxylated multiwalled carbon nanotubes modified with titanium nitride nanoparticles.

Mikrochim Acta 2018 Dec 10;186(1). Epub 2018 Dec 10.

Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, 106, Taiwan, Republic of China.

A glassy carbon electrode (GCE) was modified with a nanocomposite prepared from carboxylated multiwalled carbon nanotubes (c-MWCNT) and titanium nitride (TiN) nanoparticles to obtain a sensor for nitrite. The nanocomposite was characterized by transmission electron microscopy, elemental mapping, X-ray diffraction, and Raman spectroscopy. Electrochemical studies results show the modified GCE to possess a low electrochemical resistance (Rct = 7 Ω) and a large electroactive surface (A = 0. Read More

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December 2018
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Predictors of cognitive function in the acute phase after aneurysmal subarachnoid hemorrhage.

Acta Neurochir (Wien) 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurosurgery, Oslo University Hospital, Rikshospitalet, P.B. 4950, Nydalen, 0424, Oslo, Norway.

Background: Cognitive dysfunction is the most common form of neurological impairment after aneurysmal subarachnoid hemorrhage (aSAH) in the chronic phase. Cognitive deficits in the acute phase after aSAH, however, remain scarcely investigated. The aim of the present study was to test cognitive function and to identify medical predictors of cognitive deficits in the acute phase of aSAH. Read More

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December 2018
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Gamma Knife radiosurgery for intravestibular and intracochlear schwannomas.

Acta Neurochir (Wien) 2018 Dec 8. Epub 2018 Dec 8.

Centre Hospitalier Universitaire Vaudois (CHUV), Neurosurgery Service and Gamma Knife Center, Rue du Bugnon 44-46, BH-08, CH-1011, Lausanne, Switzerland.

Background: Schwannomas of the VIIIth cranial nerve are benign tumours, with vast majority occurring in vestibular division. Rarely, they can also arise from distal branches of cochlear, superior or inferior vestibular. We review our experience with Gamma Knife radiosurgery (GKR), as first intention treatment for intracochlear (ICS) and intravestibular (IVS) schwannomas. Read More

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December 2018

Hearing preservation in small acoustic neuroma: observation or active therapy? Literature review and institutional experience.

Acta Neurochir (Wien) 2018 Dec 8. Epub 2018 Dec 8.

Academic Neurosurgery, Department of Neurosciences, University Hospital of Padova, Via Giustiniani 2, 35128, Padova, Italy.

Background: Current imaging modalities enable early diagnosis of a large number of small acoustic neuromas in patients with well-preserved hearing, whose best management is still a debatable matter.

Methods: Comparing the hearing outcome of the various therapeutical approaches, including observation, radiosurgery, or resective surgery, is not easy because of the numerous classifications measuring hearing in different ways. In this review, a literature review was performed and papers selected dealing with small tumors, short- and long-term hearing, tumor control or radical resection, and effect of pre-treatment hearing and size on outcome. Read More

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December 2018

A colorimetric mercury(II) assay based on the Hg(II)-stimulated peroxidase mimicking activity of a nanocomposite prepared from graphitic carbon nitride and gold nanoparticles.

Mikrochim Acta 2018 Dec 10;186(1). Epub 2018 Dec 10.

Key Laboratory of Predictive Microbiology and Chemical Residual Analysis, College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China.

A one-step reduction method was used for the preparation of stable graphitic carbon nitride-gold nanoparticles (g-CN-Au) nanocomposites from ultrathin g-CN nanosheets and chloroauric acid by using NaBH as a reducing agent under ultrasonication. The nanocomposites were characterized by transmission electron microscopy, X-ray photoelectron spectroscopy, UV-Vis absorption and fluorescence spectroscopy etc. The results revealed that the gold nanoparticles (AuNPs) are uniformly formed on the g-CN nanosheets. Read More

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December 2018

Social media for dissemination and public engagement in neurosurgery-the example of Brainbook.

Acta Neurochir (Wien) 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurosurgery, The Royal London Hospital, London, UK.

Background: Public engagement has become one of the most effective tools in gaining feedback and perspectives from members of the public, involving patients with decisions, and inspiring young people to carry the medical profession forwards. Brainbook is a multi-platform, social media-based resource that was created specifically to enhance public engagement in neurosurgery and results from one of its case discussions will be reported in this paper.

Methods: A Brainbook case was created in collaboration with the NIHR Global Health Research Group on Neurotrauma and presented over 3 days (23-25 February 2018). Read More

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December 2018

A non-enzymatic voltammetric xanthine sensor based on the use of platinum nanoparticles loaded with a metal-organic framework of type MIL-101(Cr). Application to simultaneous detection of dopamine, uric acid, xanthine and hypoxanthine.

Mikrochim Acta 2018 Dec 10;186(1). Epub 2018 Dec 10.

School of Materials Science and Engineering, College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin, 150040, China.

A Cr-based metal-organic framework MIL-101(Cr) was used to load platinum nanoparticles (PtNPs) that were placed on a glassy carbon electrode (GCE). The modified GCE was used as a non-enzymatic xanthine sensor. Compared to bare GCE, it requires a strongly decreased working potential and an increased signal current for xanthine oxidation. Read More

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December 2018

Management and pregnancy outcomes of women with GCK-MODY enrolled in the US Monogenic Diabetes Registry.

Acta Diabetol 2018 Dec 11. Epub 2018 Dec 11.

Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Kovler Diabetes Center, University of Chicago, 5841 South Maryland Ave., MC 1027, Chicago, IL, 60637, USA.

Aims: GCK-MODY is characterized by mild hyperglycemia. Treatment is not required outside of pregnancy. During pregnancy, insulin treatment is recommended if second trimester fetal ultrasound monitoring shows macrosomia, suggesting the fetus has not inherited the GCK gene. Read More

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December 2018

A carbon paste electrode modified with a nickel titanate nanoceramic for simultaneous voltammetric determination of ortho- and para-hydroxybenzoic acids.

Mikrochim Acta 2018 Dec 10;186(1):12. Epub 2018 Dec 10.

Department of Chemistry, Islamic Azad University, Naragh Branch, Naragh, Iran.

An electrochemical sensor is described for the simultaneous determination of ortho-hydroxybenzoic acid (OHB) and para-hydroxybenzoic acid (PHB). The sensor consists of a carbon paste electrode modified with nickel titanate nanoceramics (NiTiO/CPE). The NiTiO nanoceramics and the nanostructured modified CPE were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, electrochemical impedance spectroscopy and cyclic voltammetry. Read More

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December 2018
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Determination of the activity of alkaline phosphatase based on aggregation-induced quenching of the fluorescence of copper nanoclusters.

Mikrochim Acta 2018 Dec 7;186(1). Epub 2018 Dec 7.

Hubei Province Key Laboratory of Regional Development and Environment Response, Wuhan, 430062, China.

A rapid method is described for synthesis of copper nanoclusters (CuNCs) by utilizing L-histidine as the stabilizer and ascorbic acid (AA) as the reductant. The CuNCs display blue-green fluorescence with excitation/emission peaks at 390/485 nm. A sensitive fluorometric assay was worked out for determination of alkaline phosphatase (ALP) activity. Read More

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December 2018
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Electrochemical sandwich immunoassay for insulin detection based on the use of gold nanoparticle-modified MoS nanosheets and the hybridization chain reaction.

Mikrochim Acta 2018 Dec 7;186(1). Epub 2018 Dec 7.

Medical Examination Centre, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

A sandwich-type of electrochemical immunoassay is described for the determination of insulin. It is based on the use of a glassy carbon electrode that was modified with MoS nanosheets decorated with gold nanoparticles (AuNPs) to immobilize a large amount of first antibody (Ab). Following exposure to insulin, secondary antibody (Ab) that was cross-linked to a DNA initiator strand (T) to form an Ab@T conjugate was added to undergo a sandwich immunoreaction. Read More

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December 2018

Synthesis of CuO/g-CN composites, and their application to voltammetric sensing of glucose and dopamine.

Mikrochim Acta 2018 Dec 10;186(1):10. Epub 2018 Dec 10.

School of Nuclear Technology and Chemistry & Biology, Hubei University of Science and Technology, Xianning, 437100, China.

The preparation of 3 kinds of carbonaceous nanocomposites by hydrothermal treatment and subsequent calcination described. The first comprises a nanomaterial of type CuO/g-CN, with g-CN in mass fractions of 2, 5 and 7 wt%, respectively. The second comprises CuO/porous carbon (5 wt%), and the third comprises CuO/carbon spheres (5 wt%). Read More

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December 2018

The inhibitory effects of rosmarinic acid on catabolism induced by IL-1β in rat chondrocyte.

Acta Biochim Pol 2018 Dec 7. Epub 2018 Dec 7.

Department of Orthopedics Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People's Republic of China.

The effects of rosmarinic acid (RosA) on osteoarthritis (OA) was investigated in rat chondrocytes. Chondrocytes were isolated from rat cartilage, incubated with RosA in the presence of interleukin-1beta (IL-1β) (10 ng/ml). The production of IL-6, as well as the mRNA level of aggrecan (ACAN) and collagen 2 (COL2), were assessed. Read More

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December 2018

A singleton distractor updates the inhibitory template for visual marking.

Acta Psychol (Amst) 2018 Dec 7;192:200-211. Epub 2018 Dec 7.

Department of Psychology, Hokkaido University, Sapporo, Japan.

Visual marking, which is based on the assumption that previewing some distractors increases the efficiency of subsequent visual searches, constitutes one of the most efficient inhibitions on visual searches. The preview search task consists of a display of a subset of distractors followed by an additional display containing the remaining distractors and a target. During the preview period, an inhibitory template is thought to be formed, resulting in the prioritization of the subsequently presented items and the inhibition of the previewed items. Read More

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December 2018
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