4,385 results match your criteria Acta Physiologica Hungarica[Journal]


Pro- and anti-inflammatory factors, vascular stiffness and outcomes in chronic hemodialysis patients.

Physiol Int 2020 Jul 2. Epub 2020 Jul 2.

1FMC Dialysis Center Pécs, Pécs, Hungary.

Objective: In this observational study we addressed accelerated arteriosclerosis (AS) in patients with chronic renal failure (CRF) on hemodialysis (HD) by measuring vascular stiffness (VS) parameters and attempted to relate them to pro-inflammatory and protective factors.

Patients: 96 consecutive patients receiving regular HD were included. 20 adult patients without major renal, cardiovascular or metabolic morbidities served as controls. Read More

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http://dx.doi.org/10.1556/2060.2020.00026DOI Listing

Maturation of NMDA receptor-mediated spontaneous postsynaptic currents in the rat locus coeruleus neurons.

Physiol Int 2020 Apr 23. Epub 2020 Apr 23.

1Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran,Iran.

Introduction: During mammalian brain development, neural activity leads to maturation of glutamatergic innervations to locus coeruleus. In this study, fast excitatory postsynaptic currents mediated by N-methyl-d-aspartate (NMDA) receptors were evaluated to investigate the maturation of excitatory postsynaptic currents in locus coeruleus (LC) neurons.

Methods: NMDA receptor-mediated synaptic currents in LC neurons were evaluated using whole-cell voltage-clamp recording during the primary postnatal weeks. Read More

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http://dx.doi.org/10.1556/2060.2020.00010DOI Listing

Prenatal cigarette smoke exposure slightly alters neurobehavioral development in neonatal rats: Implications for developmental origins of health and disease (DoHAD).

Physiol Int 2020 Apr 23. Epub 2020 Apr 23.

2Department of Anatomy,University of Pécs Clinical Centre, Pécs, Hungary.

Numerous studies indicate that smoking during pregnancy exerts harmful effects on fetal brain development. The aim of this study was to determine the influence of maternal smoking during pregnancy on the early physical and neurobehavioral development of newborn rats. Wistar rats were subjected to whole-body smoke exposure for 2 × 40 min daily from the day of mating until day of delivery. Read More

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http://dx.doi.org/10.1556/2060.2020.00007DOI Listing

The association between sympatho-vagal balance and central blood pressures.

Physiol Int 2020 Apr 23. Epub 2020 Apr 23.

6Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY, USA.

Purpose: High central blood pressure is more predictive of cardiovascular disease (CVD) versus high peripheral blood pressure. Measures of central pressures (CPs) include, central systolic blood pressure (CSBP) and central diastolic blood pressure. Measures of central pressures augmentation (CPsA) include augmentation pressure (AP) and the augmentation index @ 75 beats·min-1 (AIx@75). Read More

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http://dx.doi.org/10.1556/2060.2020.00005DOI Listing

Left ventricular apical rotation is associated with mitral annular function in healthy subjects. Results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study

Physiol Int 2020 04 23. Epub 2020 Apr 23.

51st Department of Medicine, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.

Introduction: Left ventricular (LV) twist is considered an essential part of LV function due to oppositely directed LV basal and apical rotations. Several factors could play a role in determining LV rotational mechanics in normal circumstances. This study aimed to investigate the relationship between LV rotational mechanics and mitral annular (MA) size and function in healthy subjects. Read More

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http://dx.doi.org/10.1556/2060.2020.00002DOI Listing

RETRACTION NOTE TO: The effects of sericin in recovering spermatogenesis and sexual hormone levels in diabetic rats.

Physiol Int 2019 Dec 12. Epub 2019 Dec 12.

INDEGSAL and Department of Molecular Biology (Cell Biology),Universidad de León, León,Spain.

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http://dx.doi.org/10.1556/2060.106.2019.0001DOI Listing
December 2019

Stable laser-Doppler flow-motion patterns in the human cutaneous microcirculation: Implications for prospective geroscience studies.

Physiol Int 2020 Mar;107(1):134-144

1Department of Physiology, Faculty of Medicine, University of Szeged, Szeged, Hungary.

Microvascular function has been assessed by determining the rhythmic oscillations in blood flow induced by the vasomotion of resistance vessels. Although laser-Doppler flowmetry (LDF) allows simple, non-invasive evaluation of this flow-motion in the cutaneous microcirculation, the temporal and spatial reproducibility of such assessments remains unclear.In the present study, we investigated cutaneous flow-motion in three consecutive years in eight skin regions using LDF in six healthy young volunteers. Read More

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http://dx.doi.org/10.1556/2060.2020.00013DOI Listing

Pituitary adenylate cyclase activating polypeptide concentrations in the sheep mammary gland, milk, and in the lamb blood plasma after suckling.

Physiol Int 2020 Mar;107(1):92-105

6Institute of Animal Science, Faculty of the Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, Hungary.

Pituitary adenylate cyclase activating polypeptide (PACAP) is involved in development and reproduction. We previously described elevated PACAP levels in the milk compared to the plasma, and the presence of its specific PAC1 receptor in the mammary gland. This study aimed to determine PACAP and vasoactive intestinal peptide (VIP) levels in female suckling lambs compared to ewe plasma and mammary gland, as well as their age-dependent alterations. Read More

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http://dx.doi.org/10.1556/2060.2020.00006DOI Listing

The role of apoptosis in the complex pathogenesis of the most common obstetrics and gynaecology diseases.

Physiol Int 2020 Mar;107(1):106-119

2Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Pécs, Hungary.

Purpose: We aimed to assess the etiological role of apoptotic genes Bcl-2 and Bax in the background of major obstetric and gynaecological diseases.

Methods: Placental tissue samples were collected from 101 pregnancies with intrauterine growth restriction and 104 pregnancies with premature birth with 140 controll samples from term, eutrophic newborns. In addition, gene expression assessment of the genes Bax and Bcl-2 was performed in 101 uterine leiomyoma tissue samples at our disposal with 110 control cases. Read More

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http://dx.doi.org/10.1556/2060.2020.00014DOI Listing

Betanin effect on PPAR-α and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis.

Physiol Int 2020 Mar;107(1):67-81

2Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: Betanin is a betacyanin with antioxidant and anti-inflammatory activities whose effects were investigated in a nonalcoholic steatohepatitis (NASH) model.

Main Methods: Ninety-six male naval medical research institute (NMRI) mice were divided into eight groups (n = 12) including normal control, high fat diet (HFD), Sham, and positive control treated with trans-chalcone. Three experimental groups were treated with 5 mg/kg, 10 mg/kg or 20 mg/kg betanin, and a betanin protective group was also defined. Read More

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http://dx.doi.org/10.1556/2060.2020.00001DOI Listing

Instillation of bradykinin into femoral artery elicits cardiorespiratory reflexes involving perivascular afferents in anesthetized rats.

Physiol Int 2020 Mar;107(1):40-54

Department of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India.

The physiology of baroreceptors and chemoreceptors present in large blood vessels of the heart is well known in the regulation of cardiorespiratory functions. Since large blood vessels and peripheral blood vessels are of the same mesodermal origin, therefore, involvement of the latter in the regulation of cardiorespiratory system is expected. The role of perivascular nerves in mediating cardiorespiratory alterations produced after intra-arterial injection of a nociceptive agent (bradykinin) was examined in urethane-anesthetized male rats. Read More

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http://dx.doi.org/10.1556/2060.2020.00009DOI Listing

Protective effect of fennel, and its major component trans-anethole against social isolation induced behavioral deficits in rats.

Physiol Int 2020 Mar;107(1):30-39

Department of Physiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran.

Social isolation damages the nervous system by weakening the antioxidant system and leading to behavioral disorders. Fennel (Foeniculum vulgare Mill.) is an herbal plant that has antioxidant and neuroprotective properties. Read More

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http://dx.doi.org/10.1556/2060.2020.00012DOI Listing

Taxamat: Automated biodiversity data management tool - Implications for microbiome studies.

Physiol Int 2020 Mar;107(1):12-17

1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Working with biodiversity data is a computationally intensive process. Numerous applications and services provide options to deal with sequencing and taxonomy data. Professional statistics software are also available to analyze these type of data. Read More

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http://dx.doi.org/10.1556/2060.2020.00004DOI Listing

Medullary thyroid cancer is associated with high serum vitamin D level and polymorphism of vitamin D receptors.

Physiol Int 2020 Mar;107(1):120-133

5Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Thyroid cancer is the most common endocrine malignancy. Studies have observed an anti-cancer effect for vitamin D and found that polymorphisms of vitamin D receptors can influence the prevalence of various cancers. The present study investigated the serum level of vitamin D and FokI, BsmI and Tru9I polymorphisms of vitamin D receptors. Read More

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http://dx.doi.org/10.1556/2060.2020.00011DOI Listing

The protective effect of hesperidin against renal ischemia-reperfusion injury involves the TLR-4/NF-κB/iNOS pathway in rats.

Physiol Int 2020 Mar;107(1):82-91

Department of Nephrology, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272001, PR China.

Renal injury is reported to have a high mortality rate. Additionally, there are several limitations to current conventional treatments that are used to manage it. This study evaluated the protective effect of hesperidin against ischemia/reperfusion (I/R)-induced kidney injury in rats. Read More

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http://dx.doi.org/10.1556/2060.2020.00003DOI Listing

Exercise promotes heart regeneration in aged rats by increasing regenerative factors in myocardial tissue.

Physiol Int 2020 Mar;107(1):166-176

2Basic Medical Science Research Center, Histogenotech Co., Tehran, Iran.

Exercise-induced stem cell activation is implicated in cardiovascular regeneration. However, ageing limits the capacity of cellular and molecular remodelling of the heart. It has been shown that exercise improves structure regeneration and function in the process of ageing. Read More

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http://dx.doi.org/10.1556/2060.2020.00008DOI Listing

Can chlorine dioxide prevent the spreading of coronavirus or other viral infections? Medical hypotheses.

Physiol Int 2020 03 1;107(1):1-11. Epub 2020 Mar 1.

Institute of Translational Medicine and International Nephrology Research and Training Center, Semmelweis University, Budapest, Hungary.

Motivation: Viruses have caused many epidemics throughout human history. The novel coronavirus [10] is just the latest example. A new viral outbreak can be unpredictable, and development of specific defense tools and countermeasures against the new virus remains time-consuming even in today's era of modern medical science and technology. Read More

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http://dx.doi.org/10.1556/2060.2020.00015DOI Listing

A brief review on the rising incidence of chronic kidney diseases and non-alcoholic fatty liver disease.

Authors:
J Nagy T Kovács

Physiol Int 2019 Dec;106(4):305-310

2 Department of Internal Medicine, Nephrological and Diabetological Centre, Clinical Centre, Medical School, University of Pécs, Pécs, Hungary.

Chronic kidney diseases (CKDs) are the most common forms of kidney disease all around the world. The incidence of CKD is rising, which is mainly driven by population aging as well as by a global rise in hypertension, metabolic syndrome, and metabolic risk factors, particularly obesity and type-2 diabetes. The high mortality, morbidity of CKD, and the health care costs of the renal replacement therapy have led investigators to seek recent and potentially modifiable risk factors such as non-alcoholic fatty liver disease (NAFLD). Read More

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December 2019

Proprioceptive accuracy is not associated with self-reported body awareness, body competence, and affect.

Physiol Int 2019 Dec 3;106(4):347-354. Epub 2020 Jan 3.

Institute of Health Promotion and Sport Sciences, ELTE Eötvös Loránd University, Budapest, Hungary.

Purpose: Proprioception plays an essential role in motor control and in psychological functioning: it is the basis of body schema and the feeling of body ownership. There are individual differences in the processing accuracy of proprioceptive stimuli. Although proprioceptive acuity plays an important role in physical competence, there are contradictory findings concerning the role it plays in healthy psychological functioning. Read More

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December 2019

Peripherally administered KP-10 prevents development of insulin-induced hypoglycemic shock in diabetic rhesus monkeys.

Physiol Int 2019 Dec 3;106(4):335-346. Epub 2020 Jan 3.

Laboratory of Animal and Human Physiology, Department of Animal Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Aim: This study investigated whether kisspeptin-10 (KP-10) prevents diabetic rhesus monkeys from insulin-induced hypoglycemic shock.

Materials And Methods: Thirty-six adult male rhesus monkeys were used, six in each group. Diabetes was induced with streptozotocin (45 mg/kg b. Read More

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December 2019

Short-term effects of simulated microgravity on morphology and gene expression in human breast cancer cells.

Physiol Int 2019 Dec 3;106(4):311-322. Epub 2020 Jan 3.

Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.

Introduction: Microgravity has been shown to impose various effects on breast cancer cells. We exposed human breast cancer cells to simulated microgravity and studied morphology and alterations in gene expression.

Materials And Methods: Human breast cancer cells were exposed to simulated microgravity in a random positioning machine (RPM) for 24 h. Read More

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December 2019

Decrescent intensity training concurrently improves maximal anaerobic power, maximal accumulated oxygen deficit, and maximal oxygen uptake.

Physiol Int 2019 Dec 20;106(4):355-367. Epub 2019 Dec 20.

Graduate School of Health and Sports Science, Juntendo University, Inzai, Japan.

This study aimed to investigate the effects of a gradually decreasing intensity training from that corresponding to maximal anaerobic power (MAnP) to that of near maximal oxygen uptake ([Formula: see text]) (decrescent intensity training) on MAnP, maximal accumulated oxygen deficit (MAOD), and [Formula: see text] in untrained young men. Seventeen untrained young men were randomly divided into either a training (TR;  = 9) group or a control (CON;  = 8) group. The TR group performed the decrescent intensity training, whereas the CON group did not perform any exercises. Read More

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December 2019

The importance of ST elevation in V ECG leads in athletes.

Physiol Int 2019 Dec 18;106(4):368-378. Epub 2019 Dec 18.

Department of Cardiology, Flór Ferenc Hospital of Pest County, Kistarcsa, Hungary.

Background: Early repolarization in the anterior ECG leads (ERV) is considered to be a sign of right ventricular (RV) remodeling, but its etiology and importance are unclear.

Methods: A total of 243 top-level endurance-trained athletes (ETA; 183 men and 60 women, weekly training hours: 15-20) and 120 leisure-time athletes (LTA; 71 men and 49 women, weekly training hours: 5-6) were investigated. The ERV sign was evaluated concerning type of sport, gender, transthoracic echocardiographic parameters, and ECG changes, which can indicate elevated RV systolic pressure [left atrium enlargement (LAE), right atrium enlargement (RAE), RV conduction defect (RVcd)]. Read More

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December 2019

Low testosterone: Androgen deficiency, endurance exercise training, and competitive performance.

Physiol Int 2019 Dec 18;106(4):379-389. Epub 2019 Dec 18.

Department of Kinesiology, Brooks Rehabilitation College of Healthcare Sciences, Jacksonville University, Jacksonville, FL, USA.

Purpose: Our intent was to (a) characterize weekly changes in resting testosterone (T), cortisol (C), and the T:C ratio in males during an intensive endurance training program, and (b) determine if clinical androgen deficiency (AD) based upon T-level criteria developed.

Methods: An 18-week training program in which individual training volume (km/week) increased at 25% increments over baseline (BL) levels observed prior to the study beginning at 4-week intervals throughout the first 12 weeks. After 12 weeks, the volume was reduced to that of the first 4 weeks until the study end (week 18). Read More

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December 2019

Betulin attenuated liver damage by prevention of hepatic mitochondrial dysfunction in rats with alcoholic steatohepatitis.

Physiol Int 2019 Dec 17;106(4):323-334. Epub 2019 Oct 17.

Division of Biochemical Pharmacology, Institute of Biochemistry of Biologically Active Compounds, National Academy of Sciences, Grodno, Belarus.

Betulin, a pentacyclic triterpene, possesses antioxidant, anti-inflammatory and hepatoprotective properties. The aim of this study was to evaluate the impact of liver mitochondria in hepatoprotection of betulin using a rat model of alcoholic steatohepatitis induced by ethanol administration (4 g/kg, intragastric) for 8 weeks. The treatment with betulin (50 and 100 mg/kg b. Read More

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http://dx.doi.org/10.1556/2060.106.2019.26DOI Listing
December 2019
2 Reads

Coherence between oscillations in the cardiorespiratory system and tissue oxygen index in muscle recovering from intensive exercise in humans.

Physiol Int 2019 Sep;106(3):261-271

Department of Human Developmental Sciences, Faculty of Education, Hokkaido University, Sapporo, Japan.

It has been shown that the tissue oxygen index (TOI) measured by near-infrared spectroscopy oscillates at very low frequencies during recovery after exercise and that this oscillation is derived from interactions among biochemical substances involved in oxidative metabolism in skeletal muscle. As a further step, we examined whether TOI in muscle interacts through oscillation with factors related to oxygen in the cardiorespiratory system. For this examination, coherence and phase difference between the TOI in the vastus lateralis and heart rate (HR) and between TOI and arterial oxygen saturation (SpO) were sequentially determined during recovery (2-60 min) after severe cycle exercise with a workload of 7. Read More

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http://dx.doi.org/10.1556/2060.106.2019.25DOI Listing
September 2019

High-intensity interval training improved fasting blood glucose and lipid profiles in type 2 diabetic rats more than endurance training; possible involvement of irisin and betatrophin.

Physiol Int 2019 Sep 3;106(3):213-224. Epub 2019 Oct 3.

Traditional and Complementary Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.

Background And Aims: In this study, we aimed to investigate the effects of 10 weeks of high-intensity interval training (HIIT) and endurance training (END) on irisin, betatrophin, insulin, fasting blood glucose (FBG) concentrations, and lipid profiles in diabetic rats.

Methods: Twenty-four Wistar rats (weight: 200-250 g) were randomly assigned into four groups as follows: (1) control (Cnt), (2) diabetic (Dibt), (3) diabetic HIIT (Dibt-HIIT), and (4) diabetic END (Dibt-END). For inducing diabetes, after 12 h of food starvation, nicotinamide (120 mg/kg) and streptozotocin (STZ; 65 mg/kg) were intraperitoneally injected. Read More

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http://dx.doi.org/10.1556/2060.106.2019.24DOI Listing
September 2019
1 Read

Glioblastoma invasion and NMDA receptors: A novel prospect.

Physiol Int 2019 Sep 30;106(3):250-260. Epub 2019 Sep 30.

Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Raipur, India.

Purpose: Glioblastoma cells create glutamate-rich tumor microenvironment, which initiates activation of ion channels and modulates downstream intracellular signaling. N-methyl-D-aspartate receptors (NMDARs; a type of glutamate receptors) have a high affinity for glutamate. The role of NMDAR activation on invasion of glioblastoma cells and the crosstalk with α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) is yet to be explored. Read More

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http://dx.doi.org/10.1556/2060.106.2019.22DOI Listing
September 2019
1 Read

The effects of sericin in recovering spermatogenesis and sexual hormone levels in diabetic rats.

Physiol Int 2019 Sep 30:1-7. Epub 2019 Sep 30.

INDEGSAL and Department of Molecular Biology (Cell Biology), Universidad de León, León, Spain.

Sericin-S (a hydrolysate from the silk protein sericin) is a natural antioxidant, which may improve spermatogenesis while having high biological safety, thus potentially useful for the treatment of male infertility. Our objective was to determine the effects of sericin-S on the sperm parameters and sexual hormone levels in a diabetic rat model. Thirty-six adult male rats were randomly divided in two groups, inducing diabetes in one of them by intraperitoneal administration of streptozotocin (STZ; 65 mg/kg). Read More

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http://dx.doi.org/10.1556/2060.106.2019.23DOI Listing
September 2019
2 Reads

Incorporating sprouted chickpea flour in pasta increases brachial artery flow-mediated dilation.

Physiol Int 2019 Sep 30;106(3):207-212. Epub 2019 Sep 30.

Department of Exercise Science and Physical Education, Montclair State University, Montclair, NJ, USA.

Purpose: Consumption of alternative flours, such as sprouted chickpea flour, has shown increased popularity in recent years. Foods rich in antioxidants have been shown to influence brachial artery flow-mediated dilation (FMD), a non-invasive test of a crucial layer of the artery called the endothelium. Partially replacing the semolina flour in pasta with sprouted chickpea flour (SCF) may acutely affect endothelial function post-digestion. Read More

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http://dx.doi.org/10.1556/2060.106.2019.21DOI Listing
September 2019

Cocaine- and amphetamine-regulated transcript promoter regulated by nicotine in nerve growth factor-treated PC12 cells.

Physiol Int 2019 Sep 30;106(3):272-282. Epub 2019 Sep 30.

Department of Physiology, Ege University School of Medicine, Izmir, Turkey.

Nicotine and cocaine- and amphetamine-regulated transcripts (CART) have several overlapping functions, such as the regulation of reward, feeding behavior, stress response, and anxiety. Previous studies showed that nicotine regulates CART expression in various brain regions. However, the molecular mechanisms underlying this regulation are not known. Read More

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http://dx.doi.org/10.1556/2060.106.2019.27DOI Listing
September 2019

Ultrastructure of intestinal mucosa in diarrhea-predominant irritable bowel syndrome.

Physiol Int 2019 Sep 27;106(3):225-235. Epub 2019 Sep 27.

Department of Gastroenterology, Qilu Hospital, Shandong University, Shandong Province, P. R. China.

Objectives: Impaired intestinal barrier function has been demonstrated in the pathophysiology of diarrhea-predominant irritable bowel syndrome (IBS-D). This study aimed to describe the intestinal ultrastructural findings in the intestinal mucosal layer of IBS-D patients.

Methods: In total, 10 healthy controls and 10 IBS-D patients were analyzed in this study. Read More

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http://dx.doi.org/10.1556/2060.106.2019.20DOI Listing
September 2019

The gut-kidney-heart axis in chronic kidney disease.

Physiol Int 2019 Sep 27;106(3):195-206. Epub 2019 Sep 27.

Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

The recent explosion of scientific interest in the gut microbiota has dramatically advanced our understanding of the complex pathophysiological interactions between the gut and multiple organs in health and disease. Emerging evidence has revealed that the gut microbiota is significantly altered in patients with chronic kidney disease (CKD), along with impaired intestinal barrier function. These alterations allow translocation of various gut-derived products into the systemic circulation, contributing to the development and progression of CKD and cardiovascular disease (CVD), partly mediated by chronic inflammation. Read More

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http://dx.doi.org/10.1556/2060.106.2019.19DOI Listing
September 2019
1 Read

Changes in substrate utilization rates during 40 min of walking within the Fatmax range.

Physiol Int 2019 Sep 27;106(3):294-304. Epub 2019 Sep 27.

Department of Physiology, Division of Sports Physiology, Faculty of Medicine, Çukurova University, Adana, Turkey.

Background And Aims: The aim of this study was to evaluate changes in fat oxidation rate during 40 min of continuous exercise and identify the intensity at the highest fat oxidation rate (Fatmax).

Methods: A total of 14 sedentary males with age, body height, weight, and BMI averages of 29.3 ± 0. Read More

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http://dx.doi.org/10.1556/2060.106.2019.28DOI Listing
September 2019
1 Read

Role of pentraxin-3 in risk assessment of patients with metabolic syndrome.

Physiol Int 2019 Sep 27;106(3):283-293. Epub 2019 Sep 27.

2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Background: Inflammation plays a major role in the development of metabolic syndrome (MetS) and its progression. Recent studies have shown that pentraxin-3 (PTX-3), osteoprogerin (OPG), and tumor necrosis factor-alpha (TNF-α) are key factors in MetS pathophysiology, but evidence for endorsing their clinical use is currently unclear and insufficient.

Aim: The study aimed to evaluate the association between the inflammatory biomarkers' levels and the severity of MetS. Read More

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http://dx.doi.org/10.1556/2060.106.2019.18DOI Listing
September 2019

Sex differences in cardiovascular responses to orthostatic challenge in healthy older persons: A pilot study.

Physiol Int 2019 Sep 15;106(3):236-249. Epub 2019 Jul 15.

Gravitational Physiology and Medicine Research Unit, Physiology Division, Otto Loewi Center of Research in Vascular Biology, Immunity and Inflammation, Medical University of Graz, Graz, Austria.

Background: Premenopausal women show a higher incidence of orthostatic hypotension than age-matched men, but there are limited data available on sex differences in cardiovascular responses to orthostatic challenge in healthy older persons. We investigated sex differences in hemodynamic and autonomic responses to orthostatic challenge in healthy older males and females.

Materials And Methods: Fourteen older healthy women and 10 age-matched men performed a sit-to-stand test (5 min of sitting followed by 5 min of standing). Read More

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http://dx.doi.org/10.1556/2060.106.2019.16DOI Listing
September 2019

The effects of physical exercise on parahippocampal function.

Authors:
P D Loprinzi

Physiol Int 2019 Jun;106(2):114-127

1 Exercise & Memory Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi , University, MS, USA.

Objective: The objective of this study was to examine the effects of physical exercise on parahippocampal function.

Methods: Studies were identified using electronic databases, including PubMed, PsychInfo, Sports Discus, and Google Scholar. In total, 28 articles met the inclusionary criteria. Read More

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http://dx.doi.org/10.1556/2060.106.2019.10DOI Listing
June 2019
1 Read

Effects of aerobic workout on the changes in the characteristics of dynamics of the center of gravity in different age categories.

Physiol Int 2019 Jun;106(2):140-150

3 Department of Physiology, Anatomy and Neuroscience, University of Szeged , Szeged, Hungary.

Introduction: The quality and function of movements undergo deterioration due to weight gain. Aerobic training normalizes body weight, improves the health status, and in addition, it is expected to improve the dynamics of movements. The aims of this study were to prove the beneficial effects of recreational physical activities on the movements. Read More

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http://dx.doi.org/10.1556/2060.106.2019.13DOI Listing

Inspiratory threshold loading reduces lipoperoxidation in obese and normal-weight subjects.

Physiol Int 2019 Jun 4;106(2):158-167. Epub 2019 Jul 4.

4 Harvard Medical School , Boston, MA, USA.

Obesity is related to increased oxidative stress. Although low-intensity physical exercise reduces oxidative stress, obese subjects may show exercise intolerance. For these subjects, inspiratory threshold loading could be an alternative tool to reduce oxidative stress. Read More

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http://dx.doi.org/10.1556/2060.106.2019.12DOI Listing
June 2019
1 Read

A multimodal pathway including the basal ganglia in the feline brain.

Physiol Int 2019 Jun 4;106(2):95-113. Epub 2019 Jul 4.

3 Department of Anatomy, Niigata University , Niigata, Japan.

The purpose of this paper is to give an overview of our present knowledge about the feline tecto-thalamo-basal ganglia cortical sensory pathway. We reviewed morphological and electrophysiological studies of the cortical areas, located in ventral bank of the anterior ectosylvian sulcus as well as the region of the insular cortex, the suprageniculate nucleus of the thalamus, caudate nucleus, and the substantia nigra. Microelectrode studies revealed common receptive field properties in all these structures. Read More

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http://dx.doi.org/10.1556/2060.106.2019.09DOI Listing

Effects of short-term in-season plyometric training in adolescent female basketball players.

Authors:
B Meszler M Váczi

Physiol Int 2019 Jun 4;106(2):168-179. Epub 2019 Jul 4.

1 Institute of Sport Sciences and Physical Education, Faculty of Sciences, University of Pécs , Pécs, Hungary.

In this study, we tested the hypothesis that, during the regular in-seasonal basketball training, an additional 7-week plyometric training program improves lower extremity strength, balance, agility, and jump performance in adolescent female basketball players. Eighteen female basketball players less than 17 years of age were randomly assigned into an experimental group (plyometric training) and a control group. Both groups underwent the same basketball training program. Read More

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http://dx.doi.org/10.1556/2060.106.2019.14DOI Listing

Medial olivocochlear suppression in musicians versus non-musicians.

Physiol Int 2019 Jun 2;106(2):151-157. Epub 2019 Jul 2.

5 Department of Physiology, Faculty of Medicine, Trakya University , Edirne, Turkey.

The medial olivocochlear efferent (MOCE) branch synapses with outer hair cells (OHCs), and the efferent pathway can be activated via a contralateral acoustic stimulus (CAS). The activation of MOCE can change OHC motile responses and convert signals that are capable of controlling the sensitivity of the peripheral hearing system in a frequency-specific manner. The aim of this study was to examine the MOCE system activity in professional musicians using transient evoked otoacoustic emission test and CAS. Read More

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http://dx.doi.org/10.1556/2060.106.2019.11DOI Listing
June 2019
1 Read

The possible role of heat shock protein-70 induction in collagen-induced arthritis in rats.

Physiol Int 2019 Jun 2;106(2):128-139. Epub 2019 Jul 2.

2 Department of Internal Medicine, Faculty of Medicine, Tanta University , Tanta, Egypt.

Aim: This study aimed to evaluate the possible role of heat shock protein-70 (HSP70) induction by 17-allylaminodemethoxygeldanamycin (17-AAG) in collagen-induced arthritis in rats.

Material And Methods: Male Wistar rats were divided into five groups ( = 10/group) and were treated intraperitoneally twice a week for 4 weeks, namely normal control (saline), arthritis control (AR; saline), AR + 17-AAG, AR + methotrexate (MTX), and AR + 17-AAG + MTX. At the end of the treatments, arthritic score was determined and then the animals were sacrificed. Read More

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http://dx.doi.org/10.1556/2060.106.2019.17DOI Listing
June 2019
3 Reads

Blood flow restriction augments the skeletal muscle response during very low-load resistance exercise to volitional failure.

Physiol Int 2019 Jun 2;106(2):180-193. Epub 2019 Jul 2.

4 Kevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi , University, MS, USA.

The purpose of this study was to compare the acute muscular response with resistance exercise between the following conditions [labeled (% one-repetition maximum/% arterial occlusion pressure)]: high-load (70/0), very low-load (15/0), very low-load with moderate (15/40), and high (15/80) blood flow restriction pressures. Twenty-three participants completed four sets of unilateral knee extension to failure (up to 90 repetitions) with each condition, one condition per leg, each day. Muscle thickness and maximal voluntary contraction (MVC) were measured before (Pre), immediately after (Post-0), and 15 min after (Post-15) exercise and electromyography (EMG) amplitude during exercise. Read More

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http://dx.doi.org/10.1556/2060.106.2019.15DOI Listing
June 2019
2 Reads

Regulation of Wnt signaling by physical exercise in the cell biological processes of the locomotor system.

Physiol Int 2019 Mar;106(1):1-20

3 Laboratory of Laser Sports Medicine, College of Physical Education and Sports Science, South China Normal University , Guangzhou, China.

In the past decade, researches on Wnt signaling in cell biology have made remarkable progress regarding our understanding of embryonic development, bone formation, muscle injury and repair, neurogenesis, and tumorigenesis. The study also showed that physical activity can reverse age-dependent decline in skeletal muscle, preventing osteoporosis, regenerative neurogenesis, hippocampal function, cognitive ability, and neuromuscular junction formation, and the age-dependent recession is highly correlated with Wnt signaling pathways. However, how the biological processes in cell and physical activity during/following exercise affect the Wnt signaling path of the locomotor system is largely unknown. Read More

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http://dx.doi.org/10.1556/2060.106.2019.07DOI Listing
March 2019
3 Reads

Voluntary wheel running and testosterone replacement increases heart angiogenesis through miR-132 in castrated diabetic rats.

Physiol Int 2019 Mar 25;106(1):48-58. Epub 2019 Mar 25.

4 Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences , Khorramabad, Iran.

Objective: Low levels of testosterone in men with diabetes are associated with cardiovascular complications. We investigated the effect of testosterone and voluntary exercise on heart angiogenesis in castrated diabetic rats.

Methods: Sixty-three diabetic rats were treated with testosterone 2 mg/kg/day or voluntary exercise alone or combination of these two for 6 weeks. Read More

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http://dx.doi.org/10.1556/2060.106.2019.06DOI Listing
March 2019
3 Reads

Effects of aerobic versus resistance training on serum fetuin-A, fetuin-B, and fibroblast growth factor-21 levels in male diabetic patients.

Physiol Int 2019 Mar 19;106(1):70-80. Epub 2019 Mar 19.

2 Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran.

The aim of this study was to compare the effects of 8 weeks of aerobic versus resistance training programs on serum fetuin-A, fetuin-B, and fibroblast growth factor-21 (FGF-21) levels in males with type 2 diabetes mellitus. Participants (n = 34) were randomly assigned to a resistance training group (RTG; n = 12), an aerobic training group (ATG; n = 11), or a control group (n = 11). The ATG completed 30-45 min of aerobic running training at 65%-75% of the maximum heart rate. Read More

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http://dx.doi.org/10.1556/2060.106.2019.01DOI Listing
March 2019
3 Reads

Effect of voluntary exercise on intracellular signalling pathways of angiogenesis in the sciatic nerve of type 1 diabetic castrated male rats.

Physiol Int 2019 Mar 19;106(1):39-47. Epub 2019 Mar 19.

1 Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences , Tabriz, Iran.

Objectives: Impaired angiogenesis in sciatic nerve is a major complication of diabetic neuropathy. Protein kinase B (AKT) and extracellular signal regulated kinase (ERK) signaling pathways play critical roles during capillary-like network formation in the angiogenesis process.

Methods: Twenty-four adult male Wistar rats (weight: 250-300 g) were used in the research. Read More

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http://dx.doi.org/10.1556/2060.106.2019.08DOI Listing
March 2019
8 Reads

The role of astrocytes on the effects of exercise on episodic memory function.

Authors:
P D Loprinzi

Physiol Int 2019 Mar 19;106(1):21-28. Epub 2019 Mar 19.

1 Exercise & Memory Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi , University, MS, USA.

This review discusses the potential role that glial cells may play in influencing the relationship between exercise and episodic memory function. A narrative review methodology is employed. Herein, the different types of glial cells, their implications in subserving episodic memory function, and how exercise can modulate glial cell activity, particularly astrocyte functionality, are discussed. Read More

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http://dx.doi.org/10.1556/2060.106.2019.04DOI Listing
March 2019
2 Reads

Homocysteine-induced inverse expression of tissue factor and DPP4 in endothelial cells is related to NADPH oxidase activity.

Physiol Int 2019 Mar 19;106(1):29-38. Epub 2019 Mar 19.

1 Department of Pathology, Amsterdam UMC, VUmc , Amsterdam, The Netherlands.

Purpose: We previously found that homocysteine (Hcy)-induced apoptosis in endothelial cells coincided with increased NADPH oxidase (NOX) activity. In addition, in ischemic endothelial cells present in the heart, we showed that loss of serine protease dipeptidyl peptidase IV (DPP4) expression was correlated with induction of tissue factor (TF) expression. Since Hcy can initiate thrombosis through the induction of TF expression, in this study, we evaluated whether the inverse relation of TF and DPP4 is also Hcy-dependent and whether NOX-mediated reactive oxygen species (ROS) is playing a role herein. Read More

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http://dx.doi.org/10.1556/2060.106.2019.05DOI Listing
March 2019
3 Reads