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    12053 results match your criteria Acta Paediatrica[Journal]

    1 OF 242

    Reviewing and addressing the link between mass media and the increase in obesity among European children: The European Academy of Paediatrics (EAP) and The European Childhood Obesity Group (ECOG) consensus statement.
    Acta Paediatr 2017 Nov 22. Epub 2017 Nov 22.
    School of Medicine, European University Cyprus, Engomi, Cyprus.
    This study reviewed the link between social media and the growing epidemic of childhood obesity in Europe. A task force from the European Academy of Paediatrics and the European Childhood Obesity Group searched published literature and developed a consensus statement. It found that there was evidence of a strong link between obesity levels across European countries and childhood media exposure and that parents and society needed a better understanding of the influence of social media on dietary habits. Read More

    Systematic review of the effect of denosumab on children with osteogenesis imperfect showed inconsistent findings.
    Acta Paediatr 2017 Nov 20. Epub 2017 Nov 20.
    St. Joseph's Healthcare Hamilton, Hamilton, Canada.
    Osteogenesis imperfecta (OI) is a rare, inherited disorder characterised by increased bone fragility, reduced bone mass and often short stature. Most cases are due to mutations in one of the two genes encoding collagen type-1 - COL1A1 and COL1A2 (1) - and the signs and symptoms vary substantially with the disease severity. The risk of fractures is 100 times higher than the general population, even in patients with mild OI. Read More

    Maternal mood disorders and lithium exposure in utero were not associated with poor cognitive development during childhood.
    Acta Paediatr 2017 Nov 18. Epub 2017 Nov 18.
    Dep. of Pediatrics, Karolinska University Hospital, Stockholm, Sweden.
    Aim: This study evaluated whether maternal mood disorders, particularly bipolar disorder, and lithium treatment during pregnancy influenced the neonatal health and cognition of children born from 2006- 2010.

    Methods: Our study at Karolinska University Hospital, Stockholm, Sweden, focused on women with and without mood disorders and their children. Information on pharmacotherapy, mental health, delivery and neonatal complications was retrospectively collected from electronic patient records. Read More

    Randomised crossover trial showed that using breast milk or sucrose provided the same analgesic effect in preterm infants of at least 28 weeks.
    Acta Paediatr 2017 Nov 18. Epub 2017 Nov 18.
    Universidad Rey Juan Carlos Facultad de Ciencias de la Salud, Madrid, Spain.
    Aim: Repeated, on-going exposure to pain influences the growth, cognitive and motor functions, behaviour, personality and neurodevelopment of preterm infants. We compared the analgesic effects of expressed breast milk and 24% oral sucrose on preterm neonates during venipuncture.

    Methods: This multicentre randomised, non-inferiority, cross-over trial focused on five neonatal university units in Madrid, Spain, from October 2013 to October 2014. Read More

    The neonatal transport index could be used as a reference tool for the Italian perinatal care regionalisation plan.
    Acta Paediatr 2017 Nov 13. Epub 2017 Nov 13.
    Neonatal Intensive Care Unit, Neonatal Emergency Transport Service, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
    We read with interest the editorial by Hummler on the role of networks in improving perinatal and neonatal care in Acta Paediatrica (1), which dealt with healthcare systems for perinatal care. This included a reference to our paper on this subject, which was also published in the journal (2). There is general agreement that regionalising perinatal care and delivery at high-volume, high-technology hospitals reduces neonatal mortality. Read More

    Virus Detection in Critically Ill Children with Acute Respiratory Disease : A New Profile in View of New Technology.
    Acta Paediatr 2017 Nov 13. Epub 2017 Nov 13.
    Department of Pediatrics, Pediatric Critical Care Medicine, University of Alberta.
    Aim: To describe the epidemiology of critically ill children admitted to a pediatric intensive care unit (PICU) with acute respiratory disease. The association with intubation was analyzed for the three most prevalent viruses and in those with and without viral co-infection.

    Methods: Patients admitted to the PICU (2004 - 2014) with acute respiratory disease were included. Read More

    Education, school type and screen time were associated with overweight and obesity in 2,930 adolescents.
    Acta Paediatr 2017 Nov 13. Epub 2017 Nov 13.
    Department of Paediatric and Adolescent Medicine, Kepler University Hospital Linz, Austria.
    Aim: This cross-sectional study analysed the influence of socioeconomic factors on screen time, overweight and obesity.

    Methods: We asked adolescents aged 10, 14 and 17 from 10 school types in urban and rural regions in Upper Austria to complete questionnaires from December 2012 to February 2013. Their parents were also asked to complete questionnaires. Read More

    The panorama of cerebral palsy in Sweden part XII shows that patterns changed in the birth years 2007-2010.
    Acta Paediatr 2017 Nov 9. Epub 2017 Nov 9.
    Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Göteborg, Sweden.
    Aim: This was the 12th population-based study to explore the epidemiology of cerebral palsy (CP) in western Sweden.

    Methods: From 2007-2010 there were 104,713 live births in the area. We analysed the birth characteristics, aetiology and neuroimaging findings, calculated the prevalence and compared the results with previous study cohorts. Read More

    Adults who were born preterm with a very low birth weight reported a similar health-related quality of life to their term-born peers.
    Acta Paediatr 2017 Nov 8. Epub 2017 Nov 8.
    National Institute for Health and Welfare, Department of Public Health Solutions, Finland.
    Approximately 1% of European infants are born preterm with a very low birth weight (VLBW) of less than 1,500g and the first babies born at the threshold of viability who received modern neonatal intensive care are now adults. While most live healthy lives, average VLBW adults tend to have more neurodevelopmental disabilities, lower educational achievement and higher rates of chronic conditions (1). Health-related quality of life (HRQoL) is defined as a construct of physical, mental and social wellbeing. Read More

    Phototherapy is commonly used for neonatal jaundice but greater control is needed to avoid toxicity in the most vulnerable infants.
    Acta Paediatr 2017 Nov 8. Epub 2017 Nov 8.
    Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
    Aim: Limited information is available about how guidelines on phototherapy for neonatal jaundice are applied in practice and toxicity is a concern. We studied the use of phototherapy in relation to birth weight and gestational age (GA) in Norwegian neonatal intensive care units (NICUs).

    Methods: The study population was all 5,382 infants admitted to the 21 NICUs in Norway between 1 September 2013 and 31 August 2014. Read More

    Uniform national guidelines do not prevent wide variations in the clinical application of phototherapy for neonatal jaundice.
    Acta Paediatr 2017 Nov 8. Epub 2017 Nov 8.
    Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
    Aim: This study compared the use of phototherapy for neonatal jaundice in all 21 Norwegian neonatal intensive care units (NICUs) from 2013-2014 in order to improve practice.

    Methods: Information on all types of phototherapy devices were collected and irradiance was measured from random units at 20cm and 50cm from the light source. We gathered information on local practice rules, including the use of single, double or triple phototherapy, how infants were positioned, the frequency of blood sampling, rules for using reflective surfaces and interrupting phototherapy. Read More

    Effects of foetal growth restriction and preterm birth on cardiac morphology and function during infancy.
    Acta Paediatr 2017 Nov 8. Epub 2017 Nov 8.
    The Ritchie Centre, Hudson Institute of Medical Research and Department of Paediatrics, Monash University, Melbourne, Vic., Australia.
    Aim: To investigate the effects of foetal growth restriction (FGR) and prematurity on cardiac morphology and function in infancy. We hypothesised that FGR and prematurity would both alter cardiac development.

    Methods: Cardiac morphology and function were evaluated in 24 preterm FGR infants (p-FGR) and 23 preterm and 19 term appropriately grown for gestational age infants (p-AGA and t-AGA, respectively) by conventional echocardiography and Tissue Doppler Imaging. Read More

    A possible way to assess tidal exhaled nitric oxide in neonates and infants treated with nasal continuous positive airway pressure.
    Acta Paediatr 2017 Nov 6. Epub 2017 Nov 6.
    Department of Paediatrics and Adolescent Medicine, Nordsjaellands Hospital, Hilleroed, Denmark.
    The endogenous compound nitric oxide (NO) is released into the airways via inducible NO synthase (1),which has the capacity to produce NO when up-regulated by pro-inflammatory cytokines or exogenous factors, like hypoxia, bacterial toxins and viruses (2). Prematurely born infants are susceptible to various acute and chronic respiratory diseases, such as respiratory distress syndrome and bronchopulmonary dysplasia (BPD). BPD involves a range of lung function abnormalities and increases the risk of re-hospitalisation (3). Read More

    The self-reported quality of life of Lithuanian children with asthma was comparable to Western populations.
    Acta Paediatr 2017 Nov 6. Epub 2017 Nov 6.
    Department of Public Health, Institute of Health Sciences, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
    Aim: Quality of life (QoL) has been widely researched among children with asthma in Western countries, but there is a lack of data from eastern Europe, where the prevalence is relatively low, but hospital admission rates are higher. We evaluated the overall level and major determinants of QoL in Lithuanian children aged 5-11 years with asthma.

    Methods: This study was carried out in six asthma outpatient clinics in the two largest cities of Lithuania from January 2015 to July 2016. Read More

    National study shows that abusive head trauma mortality in Sweden was at least 10 times lower than in other Western countries.
    Acta Paediatr 2017 Nov 6. Epub 2017 Nov 6.
    Department of Surgical Sciences, Forensic Medicine, Uppsala University, Uppsala, Sweden.
    Aim: The validity of the diagnostic criteria for abusive head trauma (AHT) and its attributes has been widely debated. This national study investigated the possibility of false-positive and false-negative cases of fatal AHT in Sweden.

    Method: This was a retrospective evaluation of the records of 733 deceased infants up to the age of 365 days who were examined during 1994-2013 at the six forensic medicine departments. Read More

    Intravenous paracetamol was associated with closure of the ductus arteriosus in extremely premature infants.
    Acta Paediatr 2017 Nov 4. Epub 2017 Nov 4.
    PEDEGO Research Unit and Medical Research Centre Oulu, University of Oulu, Oulu, Finland.
    Aim: Symptomatic patent ductus arteriosus may lead to serious complications in extremely preterm and extremely low birthweight infants and is often resistant to medication. We evaluated early intravenous paracetamol for pain prevention during respiratory therapy, in an attempt to understand the ductal treatment of such infants.

    Methods: Our cohort were 295 extremely preterm or extremely low birthweight infants, born at less than 28 weeks or 1000 g, respectively, who were treated in the neonatal intensive care unit of Oulu University Hospital from 2002 to 2015, before and after intravenous paracetamol was introduced in June 2009. Read More

    An epidemic of meningococcal disease in children in North Norway in the 1970s and 1980s was dominated by a hypervirulent group B strain.
    Acta Paediatr 2017 Oct 28. Epub 2017 Oct 28.
    Paediatric Research Group, University of Tromsø, Tromsø, Norway.
    Aim: We examined children hospitalised for invasive meningococcal disease, a leading cause of paediatric sepsis, in Troms County, North Norway, from 1973 to 2016, including the epidemic in the 1970s and 1980s.

    Methods: This study was a retrospective review of children under the age of 15 years who were hospitalised for meningococcal disease at the University Hospital of North Norway and Harstad Hospital. We studied hospital and bacteriological records to determine the incidence rates and phenotypes involved. Read More

    Performance of risk stratification criteria in the management of febrile young infants younger than three months of age.
    Acta Paediatr 2017 Oct 28. Epub 2017 Oct 28.
    Pediatric Infectious Disease Unit, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
    Aim: We evaluated the diagnosis, risk stratification and management of febrile infants under three months of age who presented to an Israeli paediatric emergency room (ER).

    Methods: This retrospective study enrolled all febrile infants examined in the paediatric ER of Soroka Medical Center during 2010-2013. The patients were classified into low-risk and high-risk subgroups and compared by age and ethnicity. Read More

    A Serratia marcescens outbreak in a neonatal intensive care unit was successfully managed by rapid hospital hygiene interventions and screening.
    Acta Paediatr 2017 Oct 25. Epub 2017 Oct 25.
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland.
    Aim: Serratia marcescens is a rare, but important, pathogen in hospital-acquired infections, especially in neonatal units. Outbreaks may cause significant mortality among neonates. This study describes how an outbreak of S. Read More

    Skin-to-skin hospital transfers are physiologically sound and empower parents.
    Acta Paediatr 2017 Oct 23. Epub 2017 Oct 23.
    Medical Director, Neonatal transport service, Department of neonatal intensive care, Uppsala University Childrens Hospital.
    Medical care for newborn infants is provided at different levels, ranging from well-baby nurseries to highly specialised intensive care units. There have been numerous studies on neonatal transport and most of them have been descriptive and, or, quality assessments (1,2) that have had a predominantly strong focus on intensive care transport. In this issue of Acta Paediatrica, Hennequin et al (3) describe their experience of transferring relatively well babies between hospitals using skin-to-skin care (STS) during transport. Read More

    Neonatal Eating Outcome Assessment: Tool Development and Inter-rater Reliability.
    Acta Paediatr 2017 Oct 23. Epub 2017 Oct 23.
    Division of Biostatistics, Washington University School of Medicine, St. Louis, MO.
    Aim: To define the process of tool development and revision for the Neonatal Eating Outcome (NEO) Assessment and to report preliminary inter-rater reliability.

    Methods: Tool development consisted of a review of the literature and observations of feeding performance among 178 preterm infants born ≤ 32 weeks gestation. 11 neonatal therapy feeding experts provided structured feedback to establish content validity and define the scoring matrix. Read More

    Systematic review found that there was moderate evidence that vaccinating healthcare workers prevented pertussis in infants.
    Acta Paediatr 2017 Oct 20. Epub 2017 Oct 20.
    Clinical Health Science, Utrecht University, Utrecht, the Netherlands.
    This systematic review investigated the effectiveness of vaccinating healthcare workers against pertussis on the occurrence of nosocomial pertussis outbreaks or infections among unprotected infants. We focused on eight studies, with five different study designs, that involved 39,129 healthy adolescents and adults, 115 healthcare workers, 2000 simulated healthcare workers and a simulated population of 200,000 people.

    Conclusion: There was moderate evidence that tetanus-diphtheria acellular pertussis vaccinations for healthcare workers were effective in preventing pertussis in all age groups and specifically in infants. Read More

    Longitudinal study showed that the quality of life of Finnish adolescents with cerebral palsy continued to be relatively good.
    Acta Paediatr 2017 Oct 20. Epub 2017 Oct 20.
    Pediatric Neurology, Children's Hospital, University of Helsinki and Helsinki University Hospital,, Helsinki, Finland.
    Aim: This longitudinal study examined what perceptions paediatric patients with cerebral palsy (CP) and their caregivers had of the patient's quality of life (QoL). It examined changing trends as children with CP became adolescents and examined the feasibility of the Finnish version of the CP QOL-Teen questionnaire.

    Methods: Carried out in autumn 2015, this study formed part of the multi-centre Finnish national CP project and aimed to validate the CP QOL-Teen questionnaire, which was posted to 54 adolescents and their caregivers. Read More

    IMPACT-III is a valid and reliable questionnaire for assessing health-related quality of life in Swedish children with inflammatory bowel disease.
    Acta Paediatr 2017 Oct 15. Epub 2017 Oct 15.
    Department of Statistics, USBE, Umeå University, Umeå, Sweden.
    Aim: This study examined the reliability, validity and factor structure of the Swedish version of the IMPACT-III questionnaire for assessing health-related quality of life in children with inflammatory bowel disease.

    Methods: We recruited 202 participants aged eight to 18 years, who were enrolled from 16 of the 23 paediatric gastroenterology clinics across Sweden during 2010-2013. This cross-sectional study compared two versions of the IMPACT-III questionnaire - one with six factors and 35 items and one with four factors and 19 items - plus the Paediatric Quality of Life Inventory 4. Read More

    Functional variants in intercellular adhesion molecule-1 and toll-like receptor-4 genes are more frequent in children with febrile urinary tract infection with renal parenchymal involvement.
    Acta Paediatr 2017 Oct 13. Epub 2017 Oct 13.
    Pediatric Urology, Assiut University, Assiut, Egypt.
    Aim: We studied the functional polymorphisms of intercellular adhesion molecule-1 (ICAM-1) and toll-like receptor-4 (TLR-4) genes and risk of acute pyelonephritis (APN) in children attending Assiut University Children's Hospitals, Egypt, from 2011 to 2015.

    Methods: Urinary tract infections (UTIs) were diagnosed in 380 children: 98 had APN and 282 had lower UTIs. Four single-nucleotide polymorphisms in ICAM-1 and TLR-4 genes were genotyped in all subjects: ICAM-1 rs1799969 Gly241Arg, ICAM-1 rs5498 Glu469Lys, TLR-4 rs4896791 Thr399Ile and TLR-4 rs4896790 Asp299Gly. Read More

    Elevated serum adipsin may predict unsuccessful treatment for cows' milk allergy but other biomarkers do not.
    Acta Paediatr 2017 Oct 13. Epub 2017 Oct 13.
    Tampere Center for Child Health Research, Tampere University and University Hospital, Tampere, Finland.
    Aim: This study evaluated whether 15 allergy, immunology or inflammatory markers predicted the long-term use of cows' milk or milk products seven years after the start of oral immunotherapy (OIT) for cows' milk allergy in children.

    Methods: The following laboratory parameters were measured before the OIT at Tampere University Hospital, Finland, and after the six-month escalation phase: serum total immunoglobulin (Ig) E, milk-specific IgG and IgG4, eosinophil cationic protein, eosinophil-derived neurotoxin, interleukins 4, 5, 6, 10 and 12p70 and serum adipokines adiponectin, adipsin, leptin and resistin. Follow-up data from a seven-year phone questionnaire in 2015 were available for 24 children: 14 successful and 10 unsuccessful milk users. Read More

    Norepinephrine infusion improves haemodynamics in the preterm infants during septic shock.
    Acta Paediatr 2017 Oct 9. Epub 2017 Oct 9.
    Department of Pediatrics, CHU Ste-Justine, University of Montreal, Montreal, QC, Canada.
    Aim: This study evaluated the clinical and haemodynamic effects of norepinephrine infusion in preterm infants.

    Methods: The effects of norepinephrine therapy for refractory hypotension were evaluated in preterm infants between April 2009 and April 2011 at the neonatal intensive care unit of Sainte-Justine Hospital, Montreal, Quebec. Changes in haemodynamics and clinical parameters were analysed eight hours before and eight hours after the start of norepinephrine infusion, and eight hours after its cessation. Read More

    Severe obesity is a limitation for the use of body mass index standard deviation scores in children and adolescents.
    Acta Paediatr 2017 Oct 9. Epub 2017 Oct 9.
    Morbid Obesity Centre, Vestfold Hospital Trust, Tønsberg, Norway.
    Aim: We analysed the distribution of the body mass index standard deviation scores (BMI-SDS) in children and adolescents seeking treatment for severe obesity, according to the International Obesity Task Force (IOTF), World Health Organization (WHO) and the national Norwegian Bergen Growth Study (BGS) BMI reference charts and the percentage above the International Obesity Task Force 25 cut-off (IOTF-25).

    Methods: This was a cross-sectional study of 396 children aged four to 17 years, who attended a tertiary care obesity centre in Norway from 2009 to 2015. Their BMI was converted to SDS using the three growth references and expressed as the percentage above IOTF-25. Read More

    Children in out-of-home care are at high risk of somatic, dental and mental ill health.
    Acta Paediatr 2017 Oct 7. Epub 2017 Oct 7.
    Department of Paediatrics, Clinical Sciences, Lund University, Lund, Sweden.
    Aim: The Swedish Social Board has implemented a support strategy to guide out-of-home care for children, which translates as children's needs in focus (CNIF) and includes a systematic health assessment. It was fully introduced into the Skåne province in 2012 and our study covered the first four years of the CNIF health assessments, from 2012 to 2015.

    Methods: We studied children aged 0-17 years in out-of-home care who had been referred by social workers for a CNIF health assessment, using their medical records to investigate both their health and the value of the health assessments. Read More

    High blood pressure in the young: why should we care?
    Acta Paediatr 2017 Oct 7. Epub 2017 Oct 7.
    Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.
    While primary hypertension (HTN) clearly occurs in children and adolescents, the approach of many providers to such patients can best be described as ambivalent: the condition may be recognised, but is not acted upon. Such ambivalence may stem from incomplete understanding of the effects of high blood pressure in the young, which in turn is related to the shortage of information on long-term outcomes of primary childhood HTN. However, other evidence on the short- and long-term effects of blood pressure elevation in childhood clearly shows that it is not a benign condition at all. Read More

    Serum complement factor 5a levels are associated with non-alcoholic fatty liver IL-6 disease in obese children.
    Acta Paediatr 2017 Oct 5. Epub 2017 Oct 5.
    Department of Pediatrics, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
    Aim: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of progressive and chronic liver injury. Complement factor 5a (C5a) may be involved in many inflammation disorders. This study investigated levels of systemic C5a in patients with and without NAFLD and lean controls METHODS: A cross-sectional study was conducted from July 2012 to June 2013 among 96 Chinese children, aged 6-17 years, recruited from the Pediatric Department of the Second Affiliated Hospital of Xi'an Jiao Tong University: 40 obese children with NAFLD, 31 obese children without NAFLD and 25 lean controls. Read More

    Near-infrared spectroscopy is a promising noninvasive technique for monitoring the effects of feeding regimens on the cerebral and splanchnic regions.
    Acta Paediatr 2017 Sep 27. Epub 2017 Sep 27.
    Department of Maternal, Fetal and Neonatal Medicine, C. Arrigo Children's Hospital, Alessandria, Italy.
    Aim: The effects of different milk and, or, administration regimens on cerebro-splanchnic perfusion are still a matter of debate. We investigated the effects of the bolus administration of breast milk or formula on cerebro-splanchnic oximetry, function and perfusion, assessed by near-infrared spectroscopy (NIRS).

    Methods: This observational study of 30 infants fed with breast (n = 15) or formula (n = 15) milk, and matched for gestational age and birth weight, was carried out in the neonatal intensive care unit of the C Arrigo Children's Hospital, Alessandria, Italy, a tertiary-level referral centre, from October 2015 to December 2016. Read More

    Families' perceived benefits of home visits for managing paediatric obesity outweigh the potential costs and barriers.
    Acta Paediatr 2017 Sep 28. Epub 2017 Sep 28.
    Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
    Aim: Home visits have successfully been used to deliver various health services, but what role could they play in paediatric weight management? Low treatment initiation and high attrition prompted our multidisciplinary paediatric weight management clinic to investigate how families perceived the benefits and barriers of home visits.

    Methods: We focused on children with obesity aged 2-17 who were enrolled in our tertiary-level clinic in Alberta, Canada. None had received a home visit. Read More

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