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Acta Otorhinolaryngol Ital 2022 Apr;42(2):194-196

ENT-Department, Czerniakowski Hospital, Warsaw, Poland.

Acta Otorhinolaryngol Ital 2022 Apr;42(2):189-193

Unit of Otorhinolaryngology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Acta Otorhinolaryngol Ital 2022 Apr;42(2):182-188

King Abdullah Ear Specialist Center (KAESC), College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Objectives: To evaluate the safety, speech performance in noise and subjective satisfaction of patients with congenital aural atresia (CAA) implanted with the active middle ear implant.

Methods: This retrospective study included 13 patients (15 ears) implanted with middle ear implants with different methods of floating mass transducer attachment. In 6 ears, the floating mass transducer (FMT) was coupled with the short process of incus; in 8 ears, a clip coupler was used; and in one ear, a round window coupler was used. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):176-181

Department of Otolaryngology Head Neck Surgery, Complejo Hospitalario Universitario Insular Materno Infantil de Gran Canaria, Las Palmas, Spain.

Objectives: To investigate the long-term effects of cochlear implants as a treatment for patients with severe to profound neurosensory loss associated with severe tinnitus.

Methods: Prospective study in 17 adult patients with severe to profound sensorineural hearing loss associated with severe tinnitus, indicated with a Tinnitus Handicap Inventory (THI) score ≥ 58%, and hyperacusis. Measures were made on hearing, tinnitus, hyperacusis and quality of life up to 5 years after activation of the sound processor of the cochlear implant. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):169-175

Department of Sense Organs, ENT Department, Sapienza University of Rome, Rome, Italy.

Objective: To analyse hearing attention and quality of listening in a cohort of children affected by moderate to severe unilateral hearing loss, comparing a group of hearing aid users to children with no hearing aid.

Methods: Twenty-four children (12 hearing aid users, and 12 without hearing rehabilitation) underwent audiological evaluation with speech audiometry in quiet and noise, hearing attention tests, and the speech, spatial and quality of hearing questionnaire in the version for parents.

Results: Concerning speech audiometry in noise, in the most difficult condition no one in the unaided group achieved a normal speech recognition threshold score (0% 11. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):162-168

Department of Pulmonology, Semmelweis University, Budapest, Hungary.

Objective: We aimed to prospectively assess the effect of comorbidities on the occurrence of postoperative respiratory complications (PoRCs) after adenotonsillectomy in children with obstructive sleep apnoea syndrome (OSA) and whether otherwise healthy children need a higher level of postoperative monitoring.

Methods: 577 children who had OSA and underwent adenotonsillectomy were enrolled. The effects of demographics, comorbidities and OSA on PoRCs were investigated with logistic regression analysis. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):155-161

Universidade Federal de Pernambuco-Recife, Brazil and Center for Allergy and clinical immunology research at clinical hospital.

Objective: The aim of this study was to investigate the ability of Peak Nasal Inspiratory Flow (PNIF) and Peak Nasal Expiratory Flow (PNEF) measures to predict symptoms of nasal obstruction.

Methods: This is a cross-sectional study, carried out in 131 individuals (64 with symptomatic allergic rhinitis and 67 asymptomatic) aged between 16 and 50 years.

Results: PNIF and PNEF were higher among non-rhinitis. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):150-154

Department of Internal Medicine, Ataturk University Faculty of Medicine, Erzurum, Turkey.

Objective: The aim of this study was to investigate the relationship between differentiated thyroid carcinomas (DTCs), histopathological findings and systemic immune-inflammation index (SII) [neutrophil (N) x platelet (P) / lymphocyte (L)] values.

Methods: 93 patients with DTC were included. N, P and L levels were measured, and the relationship between the SII and histopathological findings was determined. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):140-149

Division of Otolaryngology and Head and Neck Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.

Background: This study aimed to evaluate the performance of the 2017 8 TNM edition and the latest update in 2020 compared to the 7 in a large cohort of patients affected by oral tongue squamous cell carcinoma (OTSCC), considering all stages.

Materials And Methods: The cohort involved 300 patients affected by OTSCC treated with surgery. All cases were classified according to the 7, 8 (2017), and the latest updated TNM edition (October 2020),. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):126-139

Department of Medical Oncology, CRO Aviano, Pordenone, Italy.

Objective: The prognostic significance of the resection margins is still subject of conflicting opinions. The purpose of this paper is to report the results of a study on the margins in carcinoma of the oral cavity, oro-hypopharynx and larynx.

Methods: A multicentre prospective study was carried out between 2015 and 2018 with the participation of 10 Italian reference hospitals. Read More

Acta Otorhinolaryngol Ital 2022 Apr;42(2):106-115

International Federation of Otorhinolaryngological Societies (YO-IFOS) Head and Neck Research Group, Paris, France.

Acta Otorhinolaryngol Ital 2022 Apr;42(2):99-105

Unit of Otorhinolaryngology - Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, School of Medicine, Genoa, Italy.

Objective: The COVID-19 pandemic was an extraordinary challenge for the global healthcare system not only for the number of patients affected by pulmonary disease, but also for the incidence of long-term sequalae. In this regard, laryngo-tracheal stenosis (LTS) represents one of the most common complications of invasive ventilation.

Methods: A case series of patients who underwent tracheal resection and anastomosis (TRA) for post-COVID-19 LTS was collected from June 2020 to September 2021. Read More

Acta Otorhinolaryngol Ital 2022 Apr 8. Epub 2022 Apr 8.

Unit of Otolaryngology, University of Foggia, Foggia, Italy.

Introduction: Nasal endoscopy is likely to be the method of choice to evaluate nasal obstruction and adenoid hypertrophy (AH) in children given its excellent diagnostic accuracy and low risk for the patient. The aim of this study was to update the previous classification of AH to guide physicians in choosing the best therapeutic option.

Materials And Methods: This is a retrospective observational study including 7621 children (3565 females; mean age 5. Read More

Acta Otorhinolaryngol Ital 2022 Apr 8. Epub 2022 Apr 8.

Unit of Otolaryngology, Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Objective: To review our 5-year experience with a modified version of glossoepiglottopexy for treatment of obstructive sleep apnoea syndrome (OSA) in two hospitals.

Methods: A retrospective analysis was carried out on a cohort of adult patients affected by OSA suffering from primary collapse of the epiglottis who underwent a modified glossoepiglottopexy. All patients underwent drug-induced sleep endoscopy, polysomnographic and swallowing evaluation, and assessment with the Epworth Sleepiness Scale (ESS). Read More

Acta Otorhinolaryngol Ital 2022 Apr 8. Epub 2022 Apr 8.

Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Itay.

Objective: The PRO.M.E. Read More

Acta Otorhinolaryngol Ital 2022 Feb;42(1):97

ENT Department, Turin University, Italy.

Acta Otorhinolaryngol Ital 2022 Feb;42(1):75-81

Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

Objective: This study compared three severity measures for chronic rhinosinusitis with nasal polyps (CRSwNP). The outcome was to identify patients who are eligible for biological therapy.

Methods: 330 adult patients with CRSwNP were examined. Read More

Acta Otorhinolaryngol Ital 2022 Feb;42(1):63-74

Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Objective: Evaluate computed tomography (CT) signs that predict need for revision endoscopic sinus surgery (ESS) of chronic rhinosinusitis (CRS).

Methods: CRS patients (n = 48) underwent routine sinus CT scans and baseline ESS in 2006-2011. Lund-Mackay (LM) scores and 43 other CT signs were analysed blinded from both sides. Read More

Acta Otorhinolaryngol Ital 2022 Feb;42(1):41-54

Head Neck Oncology Unit, Candiolo Cancer Institute, FPO IRCCS, Italy.

Acta Otorhinolaryngol Ital 2022 Feb;42(1):34-40

Department of Otolaryngology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.

Objectives: chromosomal rearrangement is frequently seen in thyroid cancer, and overexpression has been shown in the follicular variant of papillary thyroid carcinoma, but not in papillary thyroid carcinoma other than the follicular variant. The main aim of this study was to investigate the frequency of overexpression among papillary thyroid carcinoma and if there were any variants of papillary thyroid carcinoma with overexpression other than the follicular variant.

Methods: Immunohistochemical analysis of overexpression was performed using a monoclonal antibody in a series of 111 paraffin-embedded blocks of thyroid tumours. Read More

Acta Otorhinolaryngol Ital 2022 Feb;42(1):17-25

Head of the Department of Head and Neck Surgery, Hospital das Clinicas, University of São Paulo School of Medicine, São Paulo, Brazil.

Introduction: Numerous studies have evaluated the prognostic significance of perineural invasion (PNI) in oral cancer; however, the results are inconclusive.

Purpose: To identify the prognostic value of PNI in oral cancer through a metanalysis.

Methods: A literature review was carried out, searching the MedLine databases via Pubmed, Scielo, Lilacs, Cochrane and Websco. Read More

Acta Otorhinolaryngol Ital 2022 02 7. Epub 2022 Feb 7.

Fondazione Policlinico Universitario A. Gemelli IRCSS, Istituto di Otorinolaringoiatria, Roma - Università Cattolica del Sacro Cuore, Rome, Italy.

Objective: To investigate the relationship between risk of Benign Paroxysmal Positional Vertigo (BPPV) recurrence and hypothyroidism treated with hormone replacement therapy (HRT).

Methods: 797 patients with idiopathic BPPV were divided into two groups: 250 patients with recurrence of BPPV (R-BPPV) and 547 patients without recurrence (NR-BPPV). Regarding patients with thyroid disease on HRT, we collected serum test results of thyroidstimulating hormone (TSH), free triiodothyronine f-T3, free thyroxine f-T4, thyroglobulin antibodies (TG-Ab) and thyroid peroxidase antibodies (TPO-Ab). Read More

Acta Otorhinolaryngol Ital 2022 Feb 7;42(1):26-33. Epub 2022 Feb 7.

Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital, Erlangen, Germany.

Objective: Development and validation of a confocal laser endomicroscopy (CLE) classification score for the larynx and pharynx.

Methods: Thirteen patients (154 video sequences, 9240 images) with laryngeal or pharyngeal SCC were included in this prospective study between October 2020 and February 2021. Each CLE sequence was correlated with the gold standard of histopathological examination. Read More

Acta Otorhinolaryngol Ital 2022 Feb 7;42(1):89-96. Epub 2022 Feb 7.

Medical Toxicology-headache and Drug Abuse Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Objective: This retrospective study aimed to verify the outcomes of stabilising occlusal splint therapy prescribed to 22 patients with unilateral definite Ménière's disease and comorbid temporomandibular joint disorder.

Methods: The results of a battery of audiometric and vestibular tests were recorded before and after 6 months of treatment, as well as the scores of disease-specific questionnaires.

Results: The average hearing threshold in the affected ear and the acoustic immittance were unchanged. Read More

Acta Otorhinolaryngol Ital 2022 Feb 7;42(1):82-88. Epub 2022 Feb 7.

Otolaryngology Unit, Department of Biomedical Sciences, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", Italy.

Objective: The aim of our study was to investigate the presence of dysphagia in patients with Obstructive Sleep Apnoea (OSA) and to correlate swallowing impairment with hypnologic and anatomic parameters.

Methods: The study population includes 36 patients suffering from OSA. Patients were divided into two groups using the presence of dysphagia as a distinctive parameter. Read More

Acta Otorhinolaryngol Ital 2022 Feb 7;42(1):55-62. Epub 2022 Feb 7.

2nd Academic ORL Department, Papageorgiou Hospital, Aristotle University, Thessaloniki, Greece.

Objective: Stenosed sphenoid sinus ostia are among the most common findings in revision endoscopic sinus surgery. This study sought to identify the optimal intraoperative sphenoidotomy size for prevention of postoperative stenosis.

Methods: 32 patients affected by chronic rhinosinusitis not associated with nasal polyps (CRSsNP) underwent 52 sphenoidotomies. Read More

Acta Otorhinolaryngol Ital 2021 Dec;41(6):576-577

Department of Otolaryngology, University Hospital of Foggia, Foggia, Italy.

Acta Otorhinolaryngol Ital 2021 Dec;41(6):566-571

Pediatric Otorhinolaryngology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

Objective: Early diagnosis of cochlear implant failures (CIF) is a critical part of post-implantation follow-up. Diagnosis is challenging and time consuming. Our study aimed to describe diagnoses of CIF with emphasis on soft failures (SF), focusing on symptoms, time from symptoms to replacement, and differences between SF and hard failures (HF). Read More

Acta Otorhinolaryngol Ital 2021 Dec;41(6):558-565

Unit of Otorhinolaryngology and Otoneurosurgery, University of Parma, Department of Medicine and Surgery, Parma, Italy.

Objective: Cochlear fistula (CF) is a rare finding, usually associated with extensive middle ear cholesteatoma. There is agreement on the fact that removing the cholesteatoma matrix on a CF exposes the ear to a high risk of sensorineural hearing loss or dead ear. The aim of the study is to describe the presentation, possible treatment strategies and related outcomes for patients with CF in chronic otitis media (COM). Read More

Acta Otorhinolaryngol Ital 2021 Dec;41(6):550-557

ENT MD freelancer, doctoral school in OSAS-EOS DRS, Milan, Italy.

Objective: Positional Obstructive Sleep Apnoea Syndrome (POSAS) is a sub-type of Obstructive Sleep Apnoea Syndrome (OSAS) in which obstructive apnoeas occur mainly in the supine sleeping position. In clinical practice, information on sleep posture is generally gathered by polysomnographic exam (PSG). The current trend in positional therapies consists of position trainers which help to avoid the supine position. Read More