10,430 results match your criteria Acta Oto-Laryngologica[Journal]


A new technique to find the facial nerve and recess by using the short process of the incus and the spine of Henle as landmarks: incus-spine angle.

Acta Otolaryngol 2018 Nov;138(11):1051-1056

a Department of Otolaryngology , University of Miami, Miller School of Medicine , Miami , FL , USA.

Background: Precise techniques to find the facial nerve (FN) and recess are lacking.

Objectives: We aimed to define incus-spine and incus-FN angles which can be used to localize the FN and recess during mastoidectomy.

Material And Methods: Thirty adult cadaveric temporal bones were studied. Read More

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http://dx.doi.org/10.1080/00016489.2018.1504168DOI Listing
November 2018

Retrospective analysis of 659 laryngeal squamous cell carcinoma patients treated with open laryngeal function-preserving operations.

Acta Otolaryngol 2018 Nov;138(11):1043-1050

a Department of Otolaryngology , Eye Ear Nose and Throat Hospital, Fudan University , Shanghai , China.

Background: Open laryngeal function-preserving surgery is a common therapeutic strategy for Chinese laryngeal squamous cell carcinoma (LSCC) patients.

Objectives: To explore the fundamental clinical characteristics and survival prognostic factors of LSCC patients treated with open laryngeal function-preserving operations.

Material And Methods: about a total of 659 LSCC patients undergoing open laryngeal function-preserving operations were retrospectively reviewed. Read More

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http://dx.doi.org/10.1080/00016489.2018.1500711DOI Listing
November 2018

Does drug induced sleep endoscopy-directed surgery improve polysomnography measures in children with Down Syndrome and obstructive sleep apnea?

Acta Otolaryngol 2018 Nov;138(11):1009-1013

c Pediatric Otolaryngology , Seattle Children's Hospital , Seattle , WA , USA.

Background: Children with Down Syndrome (DS) and obstructive sleep apnea (OSA) are difficult to treat, as first line therapies may not lead to significant improvement. Drug-induced sleep endoscopy (DISE) directed surgery may be particularly beneficial for these patients.

Objective: To assess change in polysomnography (PSG) measures of patients with DS who underwent DISE-directed surgery. Read More

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http://dx.doi.org/10.1080/00016489.2018.1504169DOI Listing
November 2018

Cochlear implantation in patients with canal wall down mastoidectomy cavities.

Acta Otolaryngol 2018 Nov;138(11):993-997

a Department of Otolaryngology-Head and Neck Surgery , Chinese PLA General Hospital , Beijing , China.

Background: Safe cochlear implantation (CI) is challenging in patients with a canal wall down (CWD) mastoidectomy cavity.

Objectives: We reviewed the outcomes of CI and proposed surgical management principles according to the presentation status of CWD mastoidectomy cavity.

Material And Methods: The cases of eight patients (nine ears) with CWD mastoidectomy cavity who underwent CI were retrospectively reviewed. Read More

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http://dx.doi.org/10.1080/00016489.2018.1500713DOI Listing
November 2018

Hyaluronan in vocal folds and false vocal folds in patients with recurrent respiratory papillomatosis.

Acta Otolaryngol 2018 Nov;138(11):1020-1027

a Department of Clinical Sciences, Division of Otorhinolaryngology , Umeå University , Umea , Sweden.

Background: Hyaluronan (HA) is a glycosaminoglycan with viscoelastic properties necessary for vocal fold (VF) vibration and voice production. Changes in HAs molecular mass, possibly related to human papilloma virus, could affect formation/persistence of recurrent respiratory papillomatosis (RRP). Aims/Objective: Describing mass and localization of HA and localization of HA receptor CD44 in VF and false vocal folds (FVF) in RRP. Read More

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http://dx.doi.org/10.1080/00016489.2018.1500712DOI Listing
November 2018

Dynamic visual acuity in benign paroxysmal positional vertigo.

Acta Otolaryngol 2018 Nov;138(11):987-992

a Department of ORL and HNS , Anadolu Medical Center , Kocaeli , Turkey.

Background: Head motions cause transient vertigo in patients with benign paroxysmal positional vertigo (BPPV) and may reduce visual ability.

Objectives: The aim is to investigate the clinical utility of dynamic visual acuity (DVA) test in those patients.

Material And Methods: Thirty patients, 11 with lateral canal BPPV (6 geotropic and 5 ageotropic), and 19 with posterior canal BPPV, were evaluated with DVA test during rapid horizontal (left and right) and vertical (up and down) head movements. Read More

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http://dx.doi.org/10.1080/00016489.2018.1498595DOI Listing
November 2018

Lermoyez syndrome revisited: 100-year mystery.

Acta Otolaryngol 2018 Nov;138(11):981-986

a Department of Otolaryngology , National Taiwan University Hospital , Taipei , Taiwan.

Objective: This study revisited seven patients with Lermoyez syndrome over the past 25 years using an inner ear test battery to elucidate its mechanism.

Methods: From 1992 to 2017, we have experienced 4096 patients with Meniere's disease (MD) and seven patients (5 males and 2 females, 8 ears) with Lermoyez syndrome. Two of the Lermoyez patients were elderly, aged 71 and 85 years. Read More

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http://dx.doi.org/10.1080/00016489.2018.1498594DOI Listing
November 2018

Diagnostic value of eye movement and vestibular function tests in patients with posterior circulation infarction.

Acta Otolaryngol 2019 Feb 15:1-11. Epub 2019 Feb 15.

a Peking University Aerospace School of Clinical Medicine , Beijing , P.R. China.

Objective: To evaluate the diagnostic value of eye movements and vestibular function tests in PCI patients.

Methods: Thirty-eight PCI patients and 31 patients with unilateral vestibular neuritis (UVN) were enrolled and underwent eye movement tests and vestibular function tests (spontaneous nystagmus [SN], head-shaking nystagmus [HSN]).

Results: The rates of eye movement abnormality were 78. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1552367DOI Listing
February 2019
3 Reads

Efficacy of combination therapy in adolescent and adult patients with total-deafness sudden sensorineural hearing loss.

Acta Otolaryngol 2019 Feb 14:1-5. Epub 2019 Feb 14.

a Department of Otolaryngology, Head and Neck Surgery , Shanghai East Hospital, Tongji University School of Medicine , Shanghai , China.

Background: Combination therapy is the first-line option for total-deafness sudden sensorineural hearing loss (SSNHL). Age may act as a crucial prognostic factor.

Objective: The aim of this study was to compare efficacy of combination therapy between adolescent and adult patients with total-deafness SSNHL. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1554266DOI Listing
February 2019
2 Reads

Binaural advantages in using a cochlear implant for adults with profound unilateral hearing loss.

Acta Otolaryngol 2019 Feb 14:1-9. Epub 2019 Feb 14.

a Institute of Physiology and Pathology of Hearing , Warsaw , Poland.

Background: Recent studies of cochlear implants (CIs) in profound unilateral hearing loss (UHL) patients have demonstrated a restoration of some binaural hearing.

Aims/objectives: The objective was to evaluate three possible advantages of binaural hearing in CIs adult users with UHL including single-side deafness (SSD) and asymmetric hearing loss (AHL) subgroups.

Material And Methods: A prospective study was conducted that included 70 sequentially implanted patients. Read More

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http://dx.doi.org/10.1080/00016489.2018.1535190DOI Listing
February 2019

Analysis on outcomes of facial paralysis complicated by middle ear cholesteatoma.

Acta Otolaryngol 2019 Feb 14:1-3. Epub 2019 Feb 14.

a Department of Neurosurgery , Lanzhou University Second Hospital , Lanzhou , China.

Background: The prognostic factors of facial paralysis complicated by middle ear cholesteatoma (MEC) are largely unknown due to limited reports and smaller sample size.

Objectives: This study aimed to analyze prognostic factors of postoperative outcomes of facial paralysis complicated by MEC.

Material And Methods: Clinical data of 48 patients (48 ears) with facial paralysis complicated by MEC were retrospectively reviewed and analyzed. Read More

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http://dx.doi.org/10.1080/00016489.2018.1543951DOI Listing
February 2019

Analysis between phenotypes and genotypes of inner ear malformation.

Acta Otolaryngol 2019 Feb 14:1-10. Epub 2019 Feb 14.

b Department of Otolaryngology-Head and Neck Surgery , Lanzhou University Second Hospital , Lanzhou , China.

Background: The clinical characteristics of LVAS have attracted more and more attention, its audiology and imaging features have also been deeply studied.

Objective: To analyze phenotypes, genotypes of EVA, and find out the relationship between them.

Methods: Sixty EVA patients were tested by audiometry, temporal bone high-resolution CT and inner ear MRI. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1554262DOI Listing
February 2019
1 Read

Development of vestibular ocular reflex and gross motor function in infants with common cavity deformity as a type of inner ear malformation.

Acta Otolaryngol 2019 Feb 14:1-6. Epub 2019 Feb 14.

b NHO Tokyo Medical Center, Department of Otolaryngology , Tokyo , Japan.

Background: The function of common cavity deformity demonstrated by temporal bone CT and MRI has been unknown.

Aim/objective: To investigate the developmental changes of vestibular ocular reflex and acquisition of postural control in infants with common cavity deformity.

Material And Methods: Eight infants who were congenitally deaf complicated by common cavity deformity were studied. Read More

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http://dx.doi.org/10.1080/00016489.2018.1548777DOI Listing
February 2019

Identification of causative variants in patients with non-syndromic hearing loss in the Minnan region, China by targeted next-generation sequencing.

Acta Otolaryngol 2019 Feb 14:1-8. Epub 2019 Feb 14.

d Xiamen Neonatal Disease Screening Center, Xiamen Maternity and Child Health Care Hospital , Xiamen , China.

Background: Due to extreme genetic heterogeneity, targeted next-generation sequencing (NGS) can be an efficient tool for rapid genetic diagnosis of hereditary non-syndromic hearing loss (NSHL).

Aims/objectives: This study was aiming to identify causative variants in NSHL patients from the Minnan region through targeted NGS.

Material And Methods: Genomic DNA samples from 90 NSHL subjects were extracted and subjected to SureSelect target enrichment system to capture the entire coding exons and flanking intronic regions of gene GJB2, SLC26A4, and MT-RNR1. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1552015DOI Listing
February 2019
1 Read

Paper patching for patulous eustachian tube.

Acta Otolaryngol 2019 Feb 14:1-7. Epub 2019 Feb 14.

a Department of Otolaryngology-Head & Neck Surgery, Division of Medical Science , Eulji University Hospital, Chungnam National University , Daejeon , Korea.

Background: Paper patching, a method that places cigarette paper over the most mobile quadrants of the tympanic membrane, is one of the treatment options for patulous eustachian tube (PET).

Aims/objectives: The objective of this study was to compare the outcomes of two different treatment strategies for PET.

Material And Methods: Twenty-three patients underwent paper patching of the tympanic membrane and 16 patients were treated with nasal saline irrigation with or without ipratropium bromide nasal spray. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1541505DOI Listing
February 2019
3 Reads

Three-dimensional finite-element analysis of the cochlear hypoplasia.

Acta Otolaryngol 2018 Nov 13;138(11):961-965. Epub 2019 Feb 13.

c Department of Clinical Neuroscience , Karolinska Institutet , Stockholm , Sweden.

Objectives: Based on CT scan images of healthy human ear, the effects of cochlear hypoplasia on auditory functions was studied.

Methods: Three-dimensional nonlinear finite-element numerical model was developed and used to predict frequency responses of hypoplastic cochleae. The numerical model was validated by comparing the modeling results to reported experimental data. Read More

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http://dx.doi.org/10.1080/00016489.2018.1497304DOI Listing
November 2018

Practical analysis of pars flaccida cholesteatoma with classification and staging system proposed by Japan Otological Society: a comparative study.

Acta Otolaryngol 2018 Nov 11;138(11):977-980. Epub 2019 Feb 11.

a Department of Otorhinolaryngology , Jikei University School of Medicine , Tokyo , Japan.

Background: The Japan Otology Society (JOS) proposed the classification and staging system for middle ear cholesteatoma. However, there was little analysis of the pathology of cholesteatoma using this staging system.

Aims/objectives: To analyze the pathology of pars flaccida cholesteatoma using the staging system by JOS. Read More

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http://dx.doi.org/10.1080/00016489.2018.1498593DOI Listing
November 2018

Oncological outcomes of surgical treatment for T3 supraglottic laryngeal squamous cell carcinoma patients.

Acta Otolaryngol 2018 Nov 8;138(11):1028-1034. Epub 2019 Feb 8.

a Department of Otorhinolaryngology , Fudan University, Eye Ear Nose and Throat Hospital , Shanghai , China.

Background: T3 supraglottic laryngeal carcinoma (LC) is a common advanced laryngeal cancer.

Objective: This study was conducted to assess the clinical results of pathological T3 (pT3) supraglottic LC patients who were amenable to laryngectomy treated with primary surgery and postoperative therapy.

Methods: Retrospective review of 202 pT3 cases of supraglottic laryngeal squamous cell carcinoma. Read More

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http://dx.doi.org/10.1080/00016489.2018.1490031DOI Listing
November 2018

Chances of reversibility in early sensory deprivation of the Homo vulnerabilis: A 5-year (and ongoing) prospective study.

Acta Otolaryngol 2019 Feb 8:1-4. Epub 2019 Feb 8.

a Clinica Las Condes, Otorrinolaringologia , Las Condes, Santiago , Chile; Colegio Marcos Goycoolea, María Esther Fuenzalida , Colina , Chile.

Background: This prospective study evaluated the effectiveness of a rehabilitation program in vulnerable children with language deficits.

Aims/objectives: Evaluating reversibility of a sensory understimulation.

Material/methods: Two groups of five students, each, (sensory and not sensory deprived) were evaluated at ages 5 and 11. Read More

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http://dx.doi.org/10.1080/00016489.2018.1538566DOI Listing
February 2019

Long-term follow-up in patients treated with electrochemotherapy for non-melanoma skin cancer in the head and neck area.

Acta Otolaryngol 2019 Feb 8:1-6. Epub 2019 Feb 8.

a Department of Otolaryngology , Orebro Universitet Institutionen for Medicinska Vetenskaper, Örebro University Hospital , Örebro , Sweden.

Background: Electrochemotherapy (ECT) is a cancer treatment modality where the intracellular accumulation of chemotherapeutic agents is enhanced by an applied electrical field.

Aims/objectives: To evaluate the long-term efficacy, safety and functional outcome after ECT treatment in high-risk non-melanoma skin cancer (NMSC) with curative intent.

Materials And Methods: Seven patients with SCC or BCC in the head and neck area were treated with ECT with intratumoral bleomycin administration. Read More

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http://dx.doi.org/10.1080/00016489.2018.1543950DOI Listing
February 2019

Role of postoperative adjuvant radiotherapy for locally advanced laryngeal cancer: a meta-analysis.

Acta Otolaryngol 2019 Feb 8:1-6. Epub 2019 Feb 8.

b Department of gastroenterology , First Affiliated Hospital of Chongqing Medical University , Chongqing , China.

Background: Studies have shown mixed results on the role of postoperative adjuvant radiotherapy (PORT) in surgically managed locally advanced laryngeal cancer.

Objectives: The aim of this study is to review and investigate the role of PORT in patients with locally advanced laryngeal cancer using meta-analysis.

Materials And Methods: Relevant studies were searched using PubMed and eligible information has been extracted. Read More

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http://dx.doi.org/10.1080/00016489.2018.1542159DOI Listing
February 2019

Acid stimulation-induced semi-pluripotent characteristics in human somatic cells.

Acta Otolaryngol 2019 Feb 8:1-7. Epub 2019 Feb 8.

e Department of Otolaryngology, Head and Neck Surgery , Chinese PLA General Hospital , Beijing , China.

Background: Clinical trials of cell-based therapies using induced pluripotent stem (iPS) cells have already been started for several neurological diseases.

Objective: The purpose of the present study was to explore the characteristics and differentiation of somatic cells in vitro undergoing a low pH treatment, so as to provide new therapeutic strategies for treating sensorineural hearing loss.

Methods: Somatic cells were treated with low pH solution to alter their characteristics. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1484565DOI Listing
February 2019
12 Reads

Safety and short-term outcomes of basic fibroblast growth factor injection for sulcus vocalis.

Acta Otolaryngol 2018 Nov 8;138(11):1014-1019. Epub 2019 Feb 8.

a Tokyo Voice Center , International University of Health and Welfare , Tokyo , Japan.

Background: Sulcus vocalis (SV) is characterized by the appearance of a groove and fibrotic changes in the vocal fold mucosa and an often irrevocable loss of tissue viscoelasticity and vibratory potential. Although several surgical approaches have been proposed, none are ideal treatments. Basic fibroblast growth factor (bFGF) may stimulate fibroblasts in the superficial layer of the lamina propria (SLP) and increase the vibration of vocal fold mucosa. Read More

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http://dx.doi.org/10.1080/00016489.2018.1497808DOI Listing
November 2018

Tumor stromal desmoplasia and inflammatory response uniquely predict survival with and without stratification for HPV tumor infection in OPSCC patients.

Acta Otolaryngol 2018 Nov 8;138(11):1035-1042. Epub 2019 Feb 8.

f Department of Clinical Medicine , University of Bergen, Haukeland University Hospital , Bergen , Norway.

Background: Oropharyngeal squamous cell carcinoma (OPSCC) positive for human papillomavirus (HPV) increases wolrd wide.

Aims/objectives: The objective for this study has been to evaluate tumor phenotypes and tumor host responses with respect to five-year disease-specific survival (DSS) in HPV(+) and HPV(-) patients.

Material And Methods: Two hundred patients with OPSCC have been treated between 1992 and 2010. Read More

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http://dx.doi.org/10.1080/00016489.2018.1497809DOI Listing
November 2018
2 Reads

Vestibular functions in patients with tinnitus only.

Acta Otolaryngol 2019 Feb 8:1-5. Epub 2019 Feb 8.

c Department of Otolaryngology, University of Miami Miller School of Medicine , Miami , FL , USA.

Objective: Tinnitus is the perception of sound in the ears or head without any external or internal acoustic stimulation, and it is usually associated with hearing loss. In addition, it has been reported that there is a relationship between vestibular problems and sensorineural hearing loss. The aim of this study was to evaluate the vestibular function in patients with tinnitus without hearing loss. Read More

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http://dx.doi.org/10.1080/00016489.2018.1548778DOI Listing
February 2019

Motor and cognitive performances in pre-lingual cochlear implant adolescents, related with vestibular function and auditory input.

Acta Otolaryngol 2019 Feb 7:1-6. Epub 2019 Feb 7.

a Laboratory of Otoneurology , British Hospital , Montevideo , Uruguay.

Background: Information about the role of auditory input and motor control is limited.

Objectives: Assessment the relationship between auditory and vestibular information with specific motor and cognitive functions.

Methods: Posturography in 17 Pre-lingual Cochlear Implant Adolescents, (PCIA) age 14. Read More

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http://dx.doi.org/10.1080/00016489.2018.1549750DOI Listing
February 2019

Otolith dysfunction in recurrent benign paroxysmal positional vertigo after mild traumatic brain injury.

Acta Otolaryngol 2019 Feb 2:1-4. Epub 2019 Feb 2.

b Department of Neurosurgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , China.

Background: The pathogenesis of recurrence of traumatic benign paroxysmal positional vertigo (BPPV) is poorly understood by far.

Objectives: To evaluate the value of secondary otolith dysfunction using vestibular evoked myogenic potential (VEMP) test in the pathogenesis of recurrence of BPPV after mild traumatic brain injury (mTBI).

Material And Methods: We reviewed 42 patients with BPPV after mTBI. Read More

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http://dx.doi.org/10.1080/00016489.2018.1562214DOI Listing
February 2019
2 Reads

The quantitative analysis of the human papillomavirus DNA load in submandibular gland lesions with droplet digital polymerase chain reaction.

Acta Otolaryngol 2019 Feb 2:1-6. Epub 2019 Feb 2.

a Department of Head and Neck Surgery , Tokyo Medical and Dental University , Yushima , Bunkyo-ku , Japan.

Background: The relationship between infection with human papillomavirus (HPV) and tumorigenesis of salivary gland remains controversial.

Objectives: This study explored the relationship between HPV and salivary gland lesions as well as that of the HPV infection status and p16 immunoreactivity. The HPV DNA loads were also quantitatively evaluated. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1562215DOI Listing
February 2019
2 Reads

Allergy accelerates the disease progression of chronic rhinosinusitis.

Acta Otolaryngol 2019 Feb 2:1-5. Epub 2019 Feb 2.

a Department of Otolaryngology , College of Medicine, National Taiwan University Hospital , Taipei , Taiwan.

Background: The role of allergy in the development of chronic rhinosinusitis (CRS) in East Asians is not clear.

Aims/objectives: The aim was to investigate the impact of allergies in the clinical characteristics of chronic rhinosinusitis.

Material And Methods: A total of 138 CRS patients who underwent endoscopic sinus surgery were included. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1552368DOI Listing
February 2019
2 Reads

Identification of bleeding sites and microwave thermal ablation of posterior epistaxis.

Acta Otolaryngol 2019 Feb 2:1-5. Epub 2019 Feb 2.

d Department of Clinical Medicine , Xinxiang Medical University , Xinxiang City, Xinxiang , China.

Background: Microwave ablation (MWA) is a relatively new technique which has been used to achieve hemostasis at surgical field. However, few publications have reported MWA for epistaxis.

Objectives: Our objectives were to identify the bleeding sites/points in instances of posterior epistaxis and to evaluate the efficacy of MWA for controlling bleeding. Read More

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http://dx.doi.org/10.1080/00016489.2018.1552016DOI Listing
February 2019
1 Read

A novel retroauricular fixed port for hemodialysis: surgical procedure and preliminary results of the clinical investigation.

Acta Otolaryngol 2019 Feb 2:1-6. Epub 2019 Feb 2.

a Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Background: Inspired by bone conduction implants, which have a low infection rate, a bone-anchored port (BAP) system for hemodialysis was designed.

Objectives: To demonstrate the surgical procedure for the BAP and to present preliminary results of the clinical investigation.

Materials And Methods: Patients with end-stage renal disease and contraindications for an arteriovenous forearm fistula were recruited for BAP implantation. Read More

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http://dx.doi.org/10.1080/00016489.2018.1562217DOI Listing
February 2019
1 Read

Silent sinus syndrome: combined sinus surgery and orbital reconstruction - report of 15 cases.

Acta Otolaryngol 2019 Feb 3:1-6. Epub 2019 Feb 3.

e Department of ENT , Clarós Clinic , Barcelona , Spain.

Background: Silent sinus syndrome (SSS) is defined as spontaneous, painless enophthalmos, hypoglobus with orbital floor resorption and maxillary sinus collapse on the ipsilateral side. Different methods of orbital floor reconstruction have been proposed.

Aims/objectives: The purpose was to analyse the results of combined endoscopic sinus surgery (ESS) and reconstruction using orbital floor implant of 15 patients with SSS and to present recent histological findings. Read More

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http://dx.doi.org/10.1080/00016489.2018.1542161DOI Listing
February 2019

Clinical outcomes of otitis media with effusion following palatoplasty in patients with incomplete cleft palate.

Acta Otolaryngol 2019 Feb 3:1-5. Epub 2019 Feb 3.

b Shanghai Children's Hospital, Shanghai Jiao Tong University, Department of Otolaryngology, Head and Neck Surgery , Shanghai , China.

Background: Diagnosis and treatment strategies for CP with OME and the timing of ear tube insertion remain controversial.

Objectives: To analyze the clinical outcomes of otitis media with effusion in children with incomplete cleft palate after palatoplasty prospectively.

Methods: A total of 30 children (10 months-2 years old) with incomplete CP were enrolled in this study and received at least 6 months of follow-up evaluations after palatoplasty. Read More

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http://dx.doi.org/10.1080/00016489.2018.1522449DOI Listing
February 2019

Presentation of second primary cancers in young laryngeal carcinoma patients.

Acta Otolaryngol 2019 Feb 3:1-5. Epub 2019 Feb 3.

a Department of Otorhinolaryngology - Head and Neck Surgery , University of Helsinki and Helsinki University Hospital , Helsinki , Finland.

Background: Laryngeal squamous cell carcinoma (LSCC) is rare in the young.

Objectives: We characterized the clinical behavior of LSCC and assessed the presentation of second primary tumors (SPCs) in this patient population.

Materials And Methods: Data from the Finnish Cancer Registry (FCR) were used to identify an epidemiological series of LSCC patients diagnosed at the age of 40 years or under, during 1953-2012 in Finland. Read More

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http://dx.doi.org/10.1080/00016489.2018.1527037DOI Listing
February 2019

Young adult patients with squamous cell carcinoma of the tongue strongly express p16 without human papillomavirus infection.

Acta Otolaryngol 2019 Feb 3:1-5. Epub 2019 Feb 3.

c Department of Pathology, Dentistry and Pharmaceutical Sciences , Okayama University Graduate School of Medicine , Okayama , Japan.

Background: Long-term smoking and drinking are known to contribute to the onset of tongue cancer (TC). However, the increasing incidence of TC in younger adults has been suggested to be associated with other factors.

Objectives: The present study investigated the relationship between TC and human papillomavirus (HPV) infection. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1541506DOI Listing
February 2019
2 Reads

The assistance of coblation in arytenoidectomy for vocal cord paralysis.

Acta Otolaryngol 2019 Feb 1:1-4. Epub 2019 Feb 1.

a Department of Otolaryngology , Xuzhou Central Hospital , Xuzhou , China.

Background: There are many causes for vocal cord paralysis, which can cause difficulty in breathing in serious cases. The common surgical methods for solving vocal cord paralysis include laryngeal splitting or laser surgery, but there are limitations. Plasma radiofrequency ablation is a new treatment with good achievements in clinical applications. Read More

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http://dx.doi.org/10.1080/00016489.2018.1542160DOI Listing
February 2019
0.990 Impact Factor

Evaluation of microRNA expression profiling in highly metastatic laryngocarcinoma cells.

Acta Otolaryngol 2018 Dec 31;138(12):1105-1111. Epub 2019 Jan 31.

f Otolaryngology Head and Neck Surgery , Chinese PLA General Hospital , Beijing , China.

Background: Until now, little is known about the role of miRNAs in the invasion and metastasis of Laryngeal squamous cell carcinoma (LSCC).

Objectives: This study aimed to explore the relationship between microRNA and the invasion and metastasis of LSCC.

Material And Methods: The highly metastatic laryngocarcinoma cells were obtained from the established animal model with spontaneous lymph node metastasis of LSCC in our previous study. Read More

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http://dx.doi.org/10.1080/00016489.2018.1508887DOI Listing
December 2018
0.990 Impact Factor

Feasibility of hearing preservation for residual hearing with longer cochlear implant electrodes.

Acta Otolaryngol 2018 Dec 31;138(12):1080-1085. Epub 2019 Jan 31.

a a Department of Otorhinolaryngology , Shinshu University School of Medicine , Matsumoto , Japan.

Background: Hearing preservation is thought to be achievable following atraumatic surgery with thin cochlear implant electrodes; therefore, the surgical approach and implant electrode design are crucial considerations.

Objective: To assess the feasibility of hearing preservation with long electrodes for patients meeting the criteria for conventional cochlear implantation.

Methods: One hundred and two patients (132 ears) who underwent cochlear implant surgery were analyzed. Read More

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http://dx.doi.org/10.1080/00016489.2018.1508888DOI Listing
December 2018

Grommets in otitis media: a 25-year follow up.

Acta Otolaryngol 2018 Dec 31;138(12):1057-1060. Epub 2019 Jan 31.

a ENT Clinic , Helsingør , Denmark.

Background: This study is unique as it is the first study which can describe the long term sequelae of treatment of otitis media with effusion (OME) with insertion of grommets in the Primary Health Sector in Denmark.

Objectives: Eardrum pathology and hearing acuity 25 years after treatment of OME by insertion of grommets, in a private ear-, nose-, and throat practice.

Material And Methods: 262 children with OME were treated from 1975 to 1978. Read More

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http://dx.doi.org/10.1080/00016489.2018.1511060DOI Listing
December 2018
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The correlation of immunologic derangement and juvenile recurrent parotitis: an investigation of the laboratory immunological observation.

Acta Otolaryngol 2018 Dec 31;138(12):1112-1116. Epub 2019 Jan 31.

a Department of Oral Surgery , Shanghai Jiaotong University School of Medicine , Shanghai , China.

Background: Juvenile recurrent parotitis (JRP) is defined as recurrent parotid inflammation, generally associated with nonobstructive sialectasis of the parotid gland. In addition, the etiology remains unclear, probably immunologically mediated.

Aim: The purposes of the present study were to report the relationship between JRP and immune function from the measurement of the JRP patients' immunoglobulins and T-lymphocyte subset. Read More

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http://dx.doi.org/10.1080/00016489.2018.1515498DOI Listing
December 2018

Oncologic and functional outcomes of salvage supracricoid partial laryngectomy.

Acta Otolaryngol 2018 Dec 31;138(12):1117-1122. Epub 2019 Jan 31.

c Department of Otorhinolaryngology , Yonsei University College of Medicine , Seodaemun-gu , Seoul , Korea.

Background: Supracricoid partial laryngectomy (SCL) can have a positive impact on patients' quality of life by circumventing dysphagia and voice problems resulting from creation of a permanent stoma after conventional total laryngectomy (TL) surgery.

Aims/objectives: The aim of this study was to investigate the oncologic and functional outcomes of salvage SCL for recurrent laryngeal carcinoma.

Material And Methods: Forty-five patients that underwent salvage surgery for recurrent laryngeal carcinoma between January 2004 and May 2015 after initial treatment failure were included in this retrospective study. Read More

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http://dx.doi.org/10.1080/00016489.2018.1506154DOI Listing
December 2018

Comparison of postoperative pain scores and dysphagia between anterior palatoplasty and uvulopalatal flap surgeries.

Acta Otolaryngol 2018 Dec 28;138(12):1092-1098. Epub 2019 Jan 28.

e Otolaryngology, Head and Neck Surgery Department, Medical Faculty , Yıldırım Beyazıt University , Ankara , Turkey.

Background: Dysphagia and pain are most common problems after soft palate surgery in obstructive sleep apnea (OSA) patients.

Objective: The aim of this study was to compare the postoperative pain scores and presence of dysphagia in patients who underwent anterior palatoplasty (AP) or uvulopalatal flap (UPF) surgeries.

Materials And Methods: In this prospective study, AP or UPF was performed on the patients with mild or moderate OSA. Read More

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http://dx.doi.org/10.1080/00016489.2018.1511058DOI Listing
December 2018
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The impact of surgical margin status on the outcomes of locally advanced hypopharyngeal squamous cell carcinoma treated by primary surgery.

Acta Otolaryngol 2018 Dec 28;138(12):1136-1145. Epub 2019 Jan 28.

b Department of Pathology , Eye and ENT Hospital of Fudan University , Shanghai , China.

Background: The extent of surgical safety margin remained unclear in hypopharyngeal carcinoma surgery.

Aim: The purpose of this study was to evaluate the influence of surgical margin status on the outcomes of patients with advanced hypopharyngeal carcinoma.

Material And Methods: A retrospective analysis of clinical data was performed in 205 patients with stage III/IV hypopharyngeal carcinoma treated by primary surgery between January 2005 and December 2014. Read More

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http://dx.doi.org/10.1080/00016489.2018.1524585DOI Listing
December 2018
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Role of blood inflammatory cells in chronic rhinosinusitis with nasal polyps.

Acta Otolaryngol 2019 Jan 28:1-4. Epub 2019 Jan 28.

a Department of Neuroscience DNS , University of Padova , Padova , Italy.

Background/objective: The pathophysiological and prognostic role of blood inflammatory cells in chronic rhinosinusitis with nasal polyps (CRSwNP) emerging from recent studies was investigated.

Material And Methods: The main available evidence and largely-recent publications were critically analyzed.

Results: Several authors reported a direct association between blood eosinophilia and CRSwNP recurrence rates. Read More

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http://dx.doi.org/10.1080/00016489.2018.1538567DOI Listing
January 2019
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Cochlear implantation outcome in straightforward cases: can we do more for adults who cannot understand speech using hearing aids alone?

Acta Otolaryngol 2018 Dec 28;138(12):1070-1079. Epub 2019 Jan 28.

a The Ear and Hearing program, Department of Otolaryngology, Bnai-Zion Medical Center , Haifa , Israel.

Background: Many adults with moderate-profound hearing loss whose speech recognition has deteriorated and are no longer benefitting from hearing aids (HAs) could benefit from cochlear implantation (CI). Of these, only <5% are implanted. In order to inform eligible patients about expected results and ease the route to implantation, better guidelines for candidate selection are needed. Read More

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http://dx.doi.org/10.1080/00016489.2018.1516298DOI Listing
December 2018

Absence of Atoh1 induced partially different cell fates of cochlear and vestibular sensory epithelial cells in mice.

Acta Otolaryngol 2018 Nov 27;138(11):972-976. Epub 2019 Jan 27.

b Department of Ophthalmology , University of Rochester , Rochester , NY , USA.

Background: Atoh1, also named Math1, is essential for the development of inner ear hair cells. Many studies have confirmed that the absence of Atoh1 resulted in a total loss of inner ear hair cells, which indicates that Atoh1 plays very similar roles in the development of hair cells in the cochlea and vestibule. Objective: The aim of this study was to evaluate whether Atoh1 plays different roles in the cochlea and vestibule. Read More

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http://dx.doi.org/10.1080/00016489.2018.1497855DOI Listing
November 2018

Current healthcare pathways in the treatment of rhinosinusitis in Germany.

Acta Otolaryngol 2018 Dec 27;138(12):1086-1091. Epub 2019 Jan 27.

d Department of Otorhinolaryngology, Head and Neck Surgery , Solingen Municipal Hospital , Solingen , Germany.

Background: In the outpatient setting in Germany, patients with rhinosinusitis usually present at general practices (GP) or ear, nose, and throat practices (ENT) for initial diagnosis and treatment.

Objectives: The aim of this study was to analyze the referral patterns of rhinosinusitis patients in GPs and ENT practices in Germany, with respect to existing recommendations.

Material And Methods: The study sample included patients from 940 GP and 106 ENT practices from Disease Analyzer database (IQVIA) who received an acute sinusitis (AS) or chronic sinusitis (CS), or nasal polyp (NP) in 2015. Read More

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http://dx.doi.org/10.1080/00016489.2018.1506153DOI Listing
December 2018

Trismus in patients with head and neck cancer and 5-year overall survival.

Acta Otolaryngol 2018 Dec 27;138(12):1123-1127. Epub 2019 Jan 27.

a Department of Surgical Sciences, Section of Otorhinolaryngology and Head & Neck Surgery , Uppsala University , Uppsala , Sweden.

Background: Trismus is a common complication of radiotherapy for head and neck cancer but its impact on survival is unknown.

Aims/objectives: This prospective study evaluates the incidence of trismus in patients with head and neck cancer receiving radiotherapy and the impact of trismus on 5-year overall survival.

Material And Methods: Two hundred forty-four patients with head and neck cancer were included. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1511059DOI Listing
December 2018
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Direct complications and routine ICU admission after total laryngectomy.

Acta Otolaryngol 2018 Dec 27;138(12):1128-1135. Epub 2019 Jan 27.

a Department of Head and Neck Surgery , Antoni van Leeuwenhoek Nederlands Kanker Instituut , Amsterdam , The Netherlands.

Background: In the Netherlands Cancer Institute (NCI), patients are admitted to the Intensive Care Unit (ICU) after total laryngectomy (TL).

Aims/objectives: To assess direct complications and the need for ICU admission after TL.

Material And Methods: Patients who underwent a TL in the NCI were reviewed on the occurrence of an event requiring ICU treatment within the first 24 hours postoperatively. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1515497DOI Listing
December 2018
2 Reads

Significance of internal auditory canal diverticula in ears with otosclerosis.

Acta Otolaryngol 2018 Dec 25;138(12):1066-1069. Epub 2019 Jan 25.

a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.

Background: Diverticula in the internal auditory canal (IAC) have been reported in ears with otosclerosis.

Objective: We evaluated hearing levels and vascular activity in ears with otosclerosis with and without IAC diverticula and clarify the significance of IAC diverticula.

Materials And Methods: Sixty-one ears from 54 patients who underwent stapes surgery for otosclerosis [fenestral (48 ears) and retrofenestral (13 ears) groups] were included in the present study. Read More

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https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1
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http://dx.doi.org/10.1080/00016489.2018.1521526DOI Listing
December 2018
2 Reads