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    10221 results match your criteria Acta Oto-Laryngologica[Journal]

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    Concomitant diseases and their effect on disease prognosis in Meniere's disease: diabetes mellitus identified as a negative prognostic factor.
    Acta Otolaryngol 2017 Sep 15:1-5. Epub 2017 Sep 15.
    a Faculty of Biochemistry and Molecular Medicine , University of Oulu , Oulu , Finland.
    Objective: To study comorbidities and their effect on the disease progression in Meniere's disease (MD).

    Methods: Retrospective study on 350 definite MD patients diagnosed according to AAO-HNS 1995 criteria using hospital records and postal questionnaire.

    Results: The prevalence of migraine, hypothyroidism, allergies, coronary heart disease and autoimmune diseases was more common in MD patients than reported in the general population of Finland. Read More

    Iatrogenic patient injuries in otology during a 10-year period: review of national patient insurance charts.
    Acta Otolaryngol 2017 Sep 14:1-5. Epub 2017 Sep 14.
    b Department of Otorhinolaryngology - Head and Neck Surgery , Helsinki University Hospital and University of Helsinki , Helsinki , Finland.
    Objective: To assess patient injury characteristics and contributing factors in otology.

    Methods: Data on the accepted patient-injury claims involving otorhinolaryngology (ORL), closed between 2001 and 2011, from the Finnish Patient Insurance Centre registry was retrieved. We included all injuries concerning otology, with evaluation and classification of their causes and types. Read More

    Adenoid cystic carcinoma of the head and neck: a retrospective multicenter study.
    Acta Otolaryngol 2017 Sep 12:1-7. Epub 2017 Sep 12.
    c Department of Otolaryngology - Head and Neck Surgery, Graduate School of Medicine , Kyoto University , Kyoto , Japan.
    Background: Adenoid cystic carcinoma of the head and neck (ACCHN) is rare and difficult to study effective treatment at one institute. Our aim is to identify prognostic factors for this disease by conducting a multicenter study at 11 institutions in Japan.

    Methods: A retrospective multicenter study of ACCHN was performed. Read More

    Predictors of prolongation in radiation treatment time in a veteran population treated with chemoradiation for oropharyngeal cancer.
    Acta Otolaryngol 2017 Sep 12:1-5. Epub 2017 Sep 12.
    c Department of Radiation Oncology , UCLA David Geffen School of Medicine , Los Angeles , CA , USA.
    Background: Prolonged radiation treatment time (RTT) is associated with worse tumor control. Here we identify and determine the implications of factors that predict treatment prolongation in Veterans Affairs (VA) patients undergoing chemoradiation.

    Methods: Chart review from July 2000 to October 2013. Read More

    Clinical and economic evaluation of minimally invasive cartilaginous palisade myringoplasty.
    Acta Otolaryngol 2017 Sep 12:1-6. Epub 2017 Sep 12.
    a Department of Otolaryngology , University Hospital of Nantes , Nantes , France.
    Objectives: To test the clinical and audiometric efficacy of a minimally invasive myringoplasty technique, combining cartilaginous palisades while avoiding flap elevation, for small and wide perforations.

    Methods: Over 4 years, this retrospective study included all patients over 6 years of age presenting an indication for myringoplasty. Several clinical and economic criteria were noted at 7 d, 2 months, 6 months and 2 years postoperative. Read More

    Sex-related hormone receptor in laryngeal squamous cell carcinoma: correlation with androgen estrogen-ɑ and prolactin receptor expression and influence of prognosis.
    Acta Otolaryngol 2017 Sep 11:1-7. Epub 2017 Sep 11.
    a Department of Head and Neck Surgery , Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , China.
    Background: The expression and function of androgen receptors (AR) and estrogen receptor alpha (ER-ɑ) in laryngeal squamous cell carcinoma (LSCC) have remained controversial for decades. Prolactin receptor (PRLR) is a sex-related hormone, that has been rarely documented in terms of expression or function compared with data on other hormone receptors in laryngeal carcinoma.

    Methods: This study reports on immunohistochemical and reverse transcription-polymerase chain reaction (RT-PCR) analysis of tumour tissue and adjacent normal tissue in 96 patients with LSCC (82 males and 14 females). Read More

    Relationship between vertebral artery blood flow in different head positions and vertigo.
    Acta Otolaryngol 2017 Sep 8:1-5. Epub 2017 Sep 8.
    c Radiology Department , Istanbul Training and Research Hospital , Istanbul , Turkey.
    Objective: To identify the vertebral artery blood flow in different head positions in patients with positional vertigo with no specific diagnosis.

    Methods: Patients with history of vestibular symptoms associated with changes in head position were enrolled into the study. Healthy volunteers were evaluated as control group. Read More

    The efficacy of the Eustachian Tube Dysfunction Questionnaire (ETDQ-7) for patulous Eustachian tube patient.
    Acta Otolaryngol 2017 Sep 7:1-4. Epub 2017 Sep 7.
    a Department of Otolaryngology - Head and Neck Surgery , Tohoku University Graduate School of Medicine , Sendai , Japan.
    Objective: To assess the efficacy of the Eustachian Tube Dysfunction Questionnaire (ETDQ-7) for patulous Eustachian tube (PET) patients.

    Methods: A prospective survey of medical records identified 36 patients and 47 ears with PET, and 15 patients and 15 ears as control. The ETDQ-7, patulous Eustachian tube handicap inventory-10 (PHI-10) and Likert scale were evaluated. Read More

    Factors associated with early diagnosis in pediatric vs adult nasopharyngeal carcinoma.
    Acta Otolaryngol 2017 Sep 6:1-4. Epub 2017 Sep 6.
    a Department of Otolaryngology , The First Affiliated Hospital of Zhengzhou University , Zhengzhou , PR China.
    Objective: To improve understanding of the initial symptom between pediatric and adult nasopharyngeal carcinoma (NPC) and to improve the early diagnosis of NPC.

    Methods: This retrospective cohort study included all 353 patients with a primary diagnosis of NPC in the First Affiliated Hospital of Zhengzhou University from January 2010 to December 2016. Of these, 34 patients were 21 years or younger (pediatric); 319 patients, older than 21 years (adult). Read More

    Age-adjusted Charlson Comorbidity Index predicts prognosis of laryngopharyngeal cancer treated with radiation therapy.
    Acta Otolaryngol 2017 Sep 6:1-6. Epub 2017 Sep 6.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Osaka General Medical Center , Sumiyoshi , Japan.
    Objectives: To examine the ability of comorbidity indices to predict the prognosis of laryngopharyngeal cancer and their association with treatment modalities.

    Methods: This retrospective study included 198 patients with laryngeal, hypopharyngeal, and oropharyngeal cancers. The effect of comorbidity indices on overall survival between surgery and (chemo)-radiation therapy ((C)RT) groups was analyzed. Read More

    Hearing disorder from music; a neglected dysfunction.
    Acta Otolaryngol 2017 Aug 31:1-4. Epub 2017 Aug 31.
    b Helsinki Ear Institute , Helsinki , Finland.
    Conclusion: Music-induced acute acoustic trauma is not inevitably linked to hearing dysfunction as validated by conventional pure tone audiometry. Tinnitus is often in combination with hyperacusis. Our results point at 'silent hearing loss' as the underlying pathology, having afferent nerve terminal damage rather than hair cell loss as the structural correlate. Read More

    A new semi-implantable middle ear implant for sensorineural hearing loss: three-years follow-up in a pilot patient's group.
    Acta Otolaryngol 2017 Aug 30:1-5. Epub 2017 Aug 30.
    a Nesmos Department, ENT Unit, Medicine and Psychology , Sapienza University , Rome , Italy.
    Objective: The aim of this article is to report on the long-term follow-up of a new semi-implantable middle ear device utilized for restoration of moderate-to-severe sensorineural hearing loss in a first series of subjects.

    Methods: Three subjects, affected by sensorineural hearing loss, have undergone implantation of Maxum(®) middle ear implant, via a transcanal approach. They all underwent an auditory assessment, paying particular attention on the pre- versus post-operative hearing levels under the unaided, best-fitted hearing aided and implant-aided conditions. Read More

    Characteristics of sinonasal fibrous dysplasia: experience from a single department.
    Acta Otolaryngol 2017 Aug 22:1-6. Epub 2017 Aug 22.
    a Department of Otolaryngology, Eye, Ear, Nose & Throat Hospital, Shanghai Key Clinical Disciplines of Otorhinolaryngology , Fudan University , Shanghai , China.
    Objectives: We summarized the characteristics of fibrous dysplasia patients in our department to obtain clinical data on this disease.

    Methods: We retrospectively reviewed 28 patients who were diagnosed with sinonasal fibrous dysplasia based on pathological examination results from March 2012 to February 2017 in our department.

    Results: The 28 patients included 16 females and 12 males, and the median age was 31. Read More

    Clinical evaluation of intravenous ampicillin as empirical antimicrobial treatment of acute epiglottitis.
    Acta Otolaryngol 2017 Aug 21:1-6. Epub 2017 Aug 21.
    a Department of Otorhinolaryngology, Head and Neck Surgery , Aarhus University Hospital , Aarhus , Denmark.
    Introduction: The significant pathogens in acute epiglottitis (AE) are poorly defined in the post Haemophilus influenza type b-vaccine era. Furthermore, there is a lack of clinical evaluations of antibiotic regimens in patients with AE. We aimed to evaluate the effectiveness of empiric intravenous ampicillin in the treatment of patients with AE. Read More

    Relative frequencies of symptoms and risk factors among patients with chronic rhinosinusitis with nasal polyps using a case-control study.
    Acta Otolaryngol 2017 Aug 21:1-4. Epub 2017 Aug 21.
    b Department of Otorhinolaryngology , Skaraborg Hospital , Skövde , Sweden.
    Objectives: The aim of this study was to investigate the relative frequency of important symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP), the link between CRSwNP and the lower airways and the importance of smoking in CRSwNP.

    Method: Three hundred and sixty-eight patients with CRSwNP and 1349 controls were recruited to the study and underwent a structured interview about symptoms from the upper and lower airways, and about smoking habits. Furthermore, all participants were clinically examined using nasal endoscopy. Read More

    Characteristic MR findings suggesting presumed labyrinthine hemorrhage.
    Acta Otolaryngol 2017 Aug 21:1-7. Epub 2017 Aug 21.
    c Department of Otolaryngology-Head and Neck Surgery , Hanyang University Guri Hospital , Guri , Korea.
    Objectives: To evaluate the magnetic resonance imaging (MRI) findings of labyrinthine hemorrhage as a cause of sudden sensorineural hearing loss (SSNHL).

    Methods: MRI scans of 59 patients with SSNHL were retrospectively analyzed and compared to clinical features and audiometry data. MR images included pre-enhanced T1-weighted, 3D FLAIR volume isometric turbo spin-echo acquisition (VISTA), post-enhanced T1-weighted and 4-h-delayed enhanced FLAIR VISTA, and 3D thin-section proton density-weighted images. Read More

    Radiological, clinical and audiological evaluation of jugular bulb-vestibular aqueduct dehiscence.
    Acta Otolaryngol 2017 Aug 11:1-5. Epub 2017 Aug 11.
    c Department of Statistics , Faculty of Art and Science, Ondokuz Mayis University , Samsun , Turkey.
    Objective: The aim of this study is to determine the prevalence of jugular bulb-vestibular aqueduct dehiscence (JBVAD) in patients undergoing temporal bone multidetector computed tomography (MDCT) and assess the relationship between JBVAD and hearing loss with the findings of audiometry.

    Methods: About 1503 temporal bone MDCT scans were evaluated for the prevalence of JBVAD. Correlation of the imaging findings and audiometric data was performed. Read More

    Administering of pregabalin and acetaminophen on management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery.
    Acta Otolaryngol 2017 Aug 8:1-4. Epub 2017 Aug 8.
    a Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine , Isfahan University of Medical Sciences , Isfahan , Iran.
    Background: Management of postoperative pain is a common problem in endoscopic sinus surgery. The objective of this study is the evaluation of pregabalin and acetaminophen effects on the management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery (FESS).

    Materials And Methods: In this clinical trial, double-blinded study, 70 patients with nasal polyposis who have indication of FESS were enrolled to this study. Read More

    Mechanisms of electrode fold-over in cochlear implant surgery when using a flexible and slim perimodiolar electrode array.
    Acta Otolaryngol 2017 Nov 8;137(11):1129-1135. Epub 2017 Aug 8.
    c Audiology Division Otorhinolaryngology Department , Las Palmas University Hospital , Las Palmas , Spain.
    Objectives: This study evaluates the design of a thin perimodiolar cochlear implant electrode array (CI532) and assesses insertion-related rotation and fold-over.

    Methods: The study consisted on a cochlear model and temporal bone insertion studies. Twenty insertions were studied, under four different surgical insertion conditions in vitro, the intracochlear disposition of the electrode array and presence of tip fold over were recorded. Read More

    Effects of pepsin A on heat shock protein 70 response in laryngopharyngeal reflux patients with chronic rhinosinusitis.
    Acta Otolaryngol 2017 Aug 8:1-7. Epub 2017 Aug 8.
    c Department of Biomedical Research , Nemours/Alfred I.duPont Hospital for Children , Wilmington , DE , USA.
    Objectives: We investigated the relationship between laryngopharyngeal reflux (LPR) and chronic rhinosinusitis (CRS), and explored the effects of pepsin A on the level of heat shock protein 70 (HSP70) in CRS.

    Methods: We included 23 CRS patients with nasal polyps (CRSwNP), 26 CRS patients without nasal polyps (CRSsNP) and nine normal controls to measure pepsin A levels in nasal secretions, blood plasma and nasal tissues, to measure HSP70 levels in nasal tissues, and to detect pepsinogen A, HSPA5, cyclo-oxygenase-2 (COX-2), and carbonic anhydrase III (CAIII) mRNA expression levels in nasal tissues.

    Results: Pepsin A levels in nasal secretions were significantly higher in CRSwNP/CRSsNP patients than in controls. Read More

    Failure patterns and prognostic factors of patients with primary mucosal melanoma of the nasal cavity and paranasal sinuses.
    Acta Otolaryngol 2017 Oct 22;137(10):1115-1120. Epub 2017 Jun 22.
    a Department of Radiation Oncology , National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Chaoyang District , Beijing , China.
    Objectives: To analyse the failure patterns and prognostic factors influencing survival in patients with primary mucosal melanoma of the nasal cavity and paranasal sinuses.

    Materials And Methods: Fifty-one patients were analysed retrospectively. Forty-eight, 33, 10, and 13 patients underwent surgery, radiotherapy, chemotherapy, and immunotherapy, respectively. Read More

    The limits of stability in patients with unilateral vestibulopathy.
    Acta Otolaryngol 2017 Oct 22;137(10):1051-1056. Epub 2017 Jun 22.
    b Department of Otorhinolaryngology , Clínica Universidad de Navarra, University Hospital and Medical School, University of Navarra , Navarra , Spain.
    Objective: To characterize the stability limits and region in patients with unilateral vestibulopathy according to the side of the lesion and determine if that imposes any bias. To analyze if the stability limits and region depend on the functional deficit as evaluated in the sensory organization test.

    Methods: Forty patients with chronic dizziness and without any vertigo spell for least 6 months prior to testing. Read More

    Sequential motion of the ossicular chain measured by laser Doppler vibrometry.
    Acta Otolaryngol 2017 Jul 31:1-5. Epub 2017 Jul 31.
    a Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine , Tottori University , Yonago , Japan.
    Objective: In order to help a surgeon make the best decision, a more objective method of measuring ossicular motion is required.

    Methods: A laser Doppler vibrometer was mounted on a surgical microscope. To measure ossicular chain vibrations, eight patients with cochlear implants were investigated. Read More

    Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas.
    Acta Otolaryngol 2017 Jul 30:1-5. Epub 2017 Jul 30.
    a Department of Otorhinolaryngology, Head and Neck Surgery and Audiology , Rigshospitalet, University of Copenhagen , Copenhagen , Denmark.
    Objectives: Human papilloma virus (HPV) is known to be associated with oropharyngeal squamous cell carcinomas (OPSCC) and may potentially play a vital role in tumor metastasis. The purpose of this study was to correlate HPV status of cervical lymph node metastases with their respective primary OPSCC tumor.

    Methods: Formalin-fixed, paraffin-embedded (FFPE) tissue samples obtained from 34 patients with cervical lymph node metastases were analyzed with HPV 16 DNA polymerase chain reaction (PCR), p16 immunohistochemistry and HPV typing. Read More

    Plunging ranula - patient characteristics, treatment, and comparison between different populations.
    Acta Otolaryngol 2017 Jul 28:1-4. Epub 2017 Jul 28.
    a Department of Otorhinolaryngology - Head and Neck Surgery , Helsinki University Hospital and University of Helsinki , Helsinki , Finland.
    Objectives: To review our clinical experience and characteristics of Finnish patients with plunging ranula and compare our results with reports from other populations.

    Design: A retrospective study from the electronic hospital records between 2005 and 2016.

    Setting: The Department of Otorhinolaryngology and Head and Neck Surgery of Helsinki University Hospital, Finland. Read More

    Treatment of the donor site of free radial flaps: vacuum sealing versus conventional wound care.
    Acta Otolaryngol 2017 Jul 28:1-6. Epub 2017 Jul 28.
    a Department of Otorhinolaryngology, Head and Neck Surgery , University Hospital of Erlangen-Nuremberg , Erlangen , Germany.
    Introduction: Radial forearm flap donor side defects can be treated by vacuum therapy and conventional wound dressing. The aim of this study was to compare different wound management considering wound healing, including risk factors and cost effectiveness.

    Materials And Methods: Retrospective study including patients treated with radial flaps in the Department of Head and Neck Surgery in Erlangen from January 2005 to August 2013. Read More

    Epidemiology and trend of pediatric adenoidectomy: a population-based study in Taiwan from 1997 to 2012.
    Acta Otolaryngol 2017 Jul 27:1-6. Epub 2017 Jul 27.
    a Department of Otolaryngology , Taipei Hospital, Ministry of Health and Welfare , New Taipei City , Taiwan.
    Objectives: To assess population-level data for pediatric adenoidectomy.

    Methods: Using data from the Taiwan National Health Insurance Research Database for the 1997-2012 period, all inpatients <18 years who received adenoidectomies were identified by codes from the International Classification of Diseases, 9th Revision.

    Results: A total of 20,599 children underwent adenoidectomy (mean age, 7. Read More

    Revision of a furosemide-loading vestibular-evoked myogenic potential protocol for detecting endolymphatic hydrops.
    Acta Otolaryngol 2017 Jul 27:1-5. Epub 2017 Jul 27.
    a Department of Otolaryngology , Kindai University Faculty of Medicine , Osakasayama City , Japan.
    Objective: The presence of endolymphatic hydrops can be suggested by improving the amplitude of vestibular-evoked myogenic potential (VEMP) after furosemide administration (furosemide loading VEMP [FVEMP]). The authors aimed to determine a stimulation frequency and judgment criteria to ascertain whether a revised FVEMP protocol can be applied to clinical settings.

    Methods: The study included 25 individuals with unilateral Meniere's disease (MD) and 11 normal healthy volunteers. Read More

    Results of preoperative chemoradiotherapy for patients with advanced cancer of the nasal cavity and paranasal sinuses.
    Acta Otolaryngol 2017 Jul 27:1-9. Epub 2017 Jul 27.
    a Department of Oncology, Institute of Clinical Sciences , Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital , Gothenburg , Sweden.
    Objectives: Curative treatment of nasal cavity and paranasal sinus cancer is challenging due to the proximity to critical anatomical structures. The purpose of this study was to analyze the impact of trimodality therapy with preoperative chemotherapy and reduced-dose radiotherapy followed by organ-preserving surgery for treating patients with nasal cavity and paranasal sinus cancer.

    Methods: This retrospective study included all 156 patients diagnosed with sinonasal cancer in western Sweden between 1986 and 2009. Read More

    Endoscopic surgery for early-stage nasopharyngeal carcinoma: a justified initial option.
    Acta Otolaryngol 2017 Nov 25;137(11):1194-1198. Epub 2017 Jul 25.
    a Department of Otolaryngology , Guangdong General Hospital and Guangdong Academy of Medical Sciences , Guangzhou , China.
    Objectives: To assess the prognosis of initial endoscopic surgery in T1N0M0 and T2N0M0 staged NPC patients.

    Materials And Methods: Between 2002 and 2016, 10 previously untreated patients with T1N0M0 or T2N0M0 staged NPC volunteered to receive endoscopic surgery followed by four courses of TPF chemotherapy. EORTC QLQ-C30 and QLQ-H&N35 were used to evaluate the QOL after treatment. Read More

    Pharyngotomy in head and neck squamous cell carcinoma: functional and oncological aspects.
    Acta Otolaryngol 2017 Jul 25:1-7. Epub 2017 Jul 25.
    a Department of Otorhinolaryngology/Head and Neck Surgery , Klinikum rechts der s Isar, Technische Universität München , München , Germany.
    Background: Head and Neck Surgery constantly has to oppose non-invasive organ preservation methods and therefore should be evaluated especially with regard to clinical and functional outcome. We will discuss the role of pharyngotomy in the treatment of HNSCC.

    Methods: Seventy-three patients with carcinoma of the oral cavity, oro-/hypopharynx and supraglottis underwent lateral/median pharyngotomy. Read More

    Results of endoscopic cartilage tympanoplasty procedure with limited tympanomeatal flap incision.
    Acta Otolaryngol 2017 Nov 25;137(11):1174-1177. Epub 2017 Jul 25.
    a Otolaryngology Department , Ege University School of Medicine , Izmir , Turkey.
    Objective: The aim of this study was to evaluate the outcomes of this minimally invasive tympanomeatal incision technique performed during endoscopic transcanal cartilage tympanoplasty.

    Study Design: Prospective clinical study.

    Methods: Eighty-seven patients (87 ears) who had TM perforation with noncomplicated COM were included. Read More

    Mild pulmonary emphysema a risk factor for interstitial lung disease when using cetuximab for squamous cell carcinoma of the head and neck.
    Acta Otolaryngol 2017 Jul 25:1-4. Epub 2017 Jul 25.
    a Department of Otorhinolaryngology, Head and Neck Surgery , Tokyo Medical University , Tokyo , Japan.
    Background: Interstitial lung disease (ILD) is an occasionally fatal adverse event associated with cetuximab (Cmab) therapy. Our objective was to clarify to what degree pulmonary emphysema is a risk factor in the treatment of head and neck cancer with Cmab through a retrospective analysis.

    Methods: Subjects were 116 patients who were administered Cmab for head and neck squamous cell carcinoma. Read More

    Foxp3 expression in lymph node metastases in patients with head and neck cancer.
    Acta Otolaryngol 2017 Nov 25;137(11):1215-1219. Epub 2017 Jul 25.
    a Department of Otorhinolaryngology, Head and Neck Surgery , Philipps-University Marburg , Marburg , Germany.
    Introduction: The prevalence and activity of regulatory T cells in patients with cancer correlates with poor prognosis. These cells are characterized by their expression of Forkhead box protein-3 (Foxp3). Squamous cell carcinoma is the most prevalent type of cancer in the head and neck region with overall poor survival rates, also due to early spread of metastatic cells. Read More

    Balanced (endoscopic medial and transcutaneous lateral) orbital decompression in Graves' orbitopathy.
    Acta Otolaryngol 2017 Nov 25;137(11):1183-1187. Epub 2017 Jul 25.
    a Department of Otolaryngology , Hospital Universitario de Fuenlabrada Madrid , Spain.
    Background: To determine the clinical outcomes and morbidity of endoscopic medial wall combined with transcutaneous lateral orbital wall decompression in Graves' orbitopathy.

    Methodology: A retrospective noncomparative case series of patients who underwent surgical decompression for Graves' orbitopathy at Hospital Universitario de Fuenlabrada between 2004 and 2014 was performed. We reviewed the patients' charts and analyzed before and after the decompression, the visual acuity (Snellen chart), optic nerve compression (fundoscopy and optic coherence tomography), exophthalmometry (Hertel measurement), ocular motility, diplopia, eyelid surgery needed after decompression and its possible complications. Read More

    Comparative study between the caloric vestibular and the video-head impulse tests in unilateral Menière's disease.
    Acta Otolaryngol 2017 Nov 25;137(11):1178-1182. Epub 2017 Jul 25.
    b Department of Otolaryngology , Clinica Universidad de Navarra , Pamplona , Spain.
    Objective: Compare the caloric vestibular test (CVT) and the video head impulse test (vHIT) in the evaluation of Meniere's disease (MD) and to analyze their diagnostic accuracy.

    Materials And Methods: Retrospective review of CVT and vHIT performed in MD patients at a tertiary care referral center in Spain.

    Results: A total of 88 patients were reviewed. Read More

    Bipolar dissection technique in parotid gland surgery.
    Acta Otolaryngol 2017 Nov 25;137(11):1210-1214. Epub 2017 Jul 25.
    a Department of Otorhinolaryngology/Head and Neck Surgery , Klinikum rechts der s Isar, Technische Universität München , München , Germany.
    Background: Parotid gland surgery (PGS) has to manage the balancing act between sufficient radicality and preservation of functional structures. While many studies evaluate post-therapeutic complication due to different extent of surgery, the current study introduces bipolar dissection (BP) being a fast and safe preparation technique.

    Methods: Analysis of clinical parameters (age, sex, tumour entity, treatment modalities, facial nerve palsy, bleeding, saliva fistula and Frey's syndrome) of 319 consecutively included patients who underwent extracapsular dissection and superficial/total/radical parotidectomy. Read More

    Intraoperative nerve monitoring reduces recurrent laryngeal nerve injury in geriatric patients undergoing thyroid surgery.
    Acta Otolaryngol 2017 Jul 25:1-6. Epub 2017 Jul 25.
    a Division of Vascular and Thyroid Surgery , Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University , Guangzhou , PR China.
    Objective: This research was aimed to investigate whether the intraoperative nerve monitoring (IONM) can reduce the incidence of recurrent laryngeal nerve (RLN) injury in geriatric patients undergoing thyroid surgery.

    Methods: This retrospective cohort study included 522 geriatric patients undergoing thyroid surgery between January 2013 and June 2016 in the Sun Yat-sen Memorial Hospital. Patients with IONM during the surgery (n = 340) were compared with patients without IONM (n = 212). Read More

    Laser surgery versus radiotherapy for T1a glottic carcinoma: a meta-analysis of oncologic outcomes.
    Acta Otolaryngol 2017 Nov 24;137(11):1204-1209. Epub 2017 Jul 24.
    a Department of Otolaryngology - Head & Neck Surgery , The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi , PR China.
    Objectives: A meta-analysis was conducted to compare oncologic outcomes for patients of T1a glottic carcinoma who were treated with laser surgery (LS) or radiotherapy (RT).

    Methods: All related studies published up to October 2016 were acquired by searching PubMed, EMBASE, and Cochrane were conducted by two authors, with the index words: vocal, glottis, larynx, laser, surgery, cordectomy, radiotherapy, radiation, irradiation, carcinoma, and cancer. Relative studies which compared oncologic outcomes between LS and RT were included. Read More

    Transcription analysis of cochlear development in minipigs.
    Acta Otolaryngol 2017 Nov 18;137(11):1166-1173. Epub 2017 Jul 18.
    d Department of Otolaryngology , Head and Neck Institute of Otolaryngology, Chinese PLA General Hospital , Beijing , China.
    Conclusions: The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss.

    Objectives: To investigate gene regulation in cochlear development and provide reference information for ear-related research. Read More

    Evaluation of YAP signaling in a rat tympanic membrane under a continuous negative pressure load and in human middle ear cholesteatoma.
    Acta Otolaryngol 2017 Nov 14;137(11):1158-1165. Epub 2017 Jul 14.
    b Department of Otorhinolaryngology , Jikei University School of Medicine , Tokyo , Japan.
    Objectives: Mechanotransduction plays an important role in cell-proliferative activities. Negative pressure in the middle ear is thought to be an important factor related to the etiology of acquired middle ear cholesteatoma. However, the correlation between negative pressure in the middle ear and the mechanism of middle ear cholesteatoma formation remains unclear. Read More

    Relationship between laryngoscopic and pathological characteristics of vocal cords leukoplakia.
    Acta Otolaryngol 2017 Nov 14;137(11):1199-1203. Epub 2017 Jul 14.
    b Department of Otolaryngology-Head and Neck Surgery , EENT Hospital, Fudan University , Shanghai , China.
    Background: To explore the relationship between the morphological characteristics and pathological diagnosis of vocal cords leukoplakia.

    Methods: A total of 1635 vocal cords were collected. The morphology were classified into three types (Type I, II, III): flat and smooth; bulge and smooth; bulge and rough. Read More

    Contralateral type of delayed endolymphatic hydrops may consist of two phenotypes based on a magnetic resonance imaging preliminary study.
    Acta Otolaryngol 2017 Nov 7;137(11):1153-1157. Epub 2017 Jul 7.
    c Department of Otolaryngology , University of Tokushima School of Medicine , Tokushima , Japan.
    Objective: This study was performed to determine the volume distribution of EH in contralateral DEH.

    Patients And Methods: Five contralateral DEH patients (age range = 21-77 years) and one ipsilateral DEH patient. Visualization of in vivo EH using 3T magnetic resonance (MR) imaging was performed by intravenous administration of gadolinium. Read More

    Residual dizziness after successful treatment of idiopathic benign paroxysmal positional vertigo originates from persistent utricular dysfunction.
    Acta Otolaryngol 2017 Nov 6;137(11):1149-1152. Epub 2017 Jul 6.
    a Department of Otolaryngology , Kindai University Faculty of Medicine , Osakasayama , Japan.
    Objective: We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following the canalith repositioning procedure for benign paroxysmal positional vertigo.

    Methods: Ocular vestibular evoked myogenic potentials were measured in 44 patients (40 included in analyses, four excluded) with successful results from the canalith repositioning procedure. The patients were examined before treatment and again one week after treatment. Read More

    Pediatric coblation total tonsillectomy: intracapsular or extracapsular?
    Acta Otolaryngol 2017 Nov 2;137(11):1188-1193. Epub 2017 Jul 2.
    a Department of Otolaryngology-Head and Neck Surgery , Capital Institute of Pediatrics affiliated Children's Hospital , Beijing , PR China.
    Objectives: To compare the results of coblation intracapsular total tonsillectomy (CITT) with those of conventional coblation extracapsular total tonsillectomy (CETT) in the treatment of tonsillar hypertrophy in children with regards to efficacy and complications.

    Methods: Ninety children with adenotonsillar hyperplasia underwent tonsillectomy ± adenoidectomy (48 CITT and 42 CETT). Intraoperative situation was observed and recorded. Read More

    Human papillomavirus and p16 protein expression as prognostic biomarkers in mobile tongue cancer.
    Acta Otolaryngol 2017 Oct 2;137(10):1121-1126. Epub 2017 Jul 2.
    b Department of Pathology , Saitama Medical University International Medical Center , Hidaka , Saitama , Japan.
    Objectives: The objectives were to determine the prevalence of human papillomavirus (HPV) in mobile tongue cancer (MTC) and evaluate associations and survival.

    Materials And Methods: Patients who underwent surgical resection as primary treatment for MTC (n = 127) were retrospectively evaluated. Formalin-fixed paraffin-embedded (FFPE) specimens were assessed for p16 and p53 by immunohistochemistry; for HPV DNA by nested multiplex polymerase chain reaction (PCR) using two pairs of consensus primers (MY09-MY11 and GP5+-GP6+); and for E6 and E7 oncogenes from 13 high-risk HPV types (16, 18, 31, 33, 35, 39, 45, 52, 56, 58, 59, 66, and 68) by real-time reverse transcription PCR (RT-PCR). Read More

    Hemodynamic stability during laryngeal electromyography procedures.
    Acta Otolaryngol 2017 Oct 23;137(10):1110-1114. Epub 2017 Jun 23.
    a Department of Otolaryngology , Chang Gung Memorial Hospital at Linkou , Taoyuan , Taiwan.
    Background: Laryngeal electromyography (LEMG) is accepted as safe, with minimal side effects. However, patient hemodynamic stability, during these procedures, has not been reported. This study aimed to investigate the hemodynamics in patients undergoing LEMG and determine the risk factors for hemodynamic changes. Read More

    Sensory organization test principally reflects utricular function.
    Acta Otolaryngol 2017 Nov 23;137(11):1143-1148. Epub 2017 Jun 23.
    a Department of Otolaryngology , Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , PR China.
    Conclusion: Our study showed that sensory organization test (SOT) could principally reflect utricular function, and our cut-score of VEST ratio (the indicator of inputs from the vestibular system in balance performance) in SOT could help to screen patients with unilateral peripheral vestibular dysfunction in non-fallers.

    Objectives: We aimed to know SOT reflects the function of which vestibular end organs and to assess the possibility of screening patients with peripheral vestibular dysfunction in non-fall population by means of SOT.

    Methods: A total of 75 patients with unilateral peripheral vestibular dysfunction underwent SOT, ocular vestibular-evoked myogenic potential (oVEMP), cervical vestibular-evoked myogenic potential (cVEMP) and caloric tests. Read More

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