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    10343 results match your criteria Acta Oto-Laryngologica[Journal]

    1 OF 207

    Efficacy and safety of a vessel sealing system in oral cancer resection and reconstructive surgery.
    Acta Otolaryngol 2018 Jun 5:1-4. Epub 2018 Jun 5.
    a Department of Head and Neck oncology and Surgery , International University of Health and Welfare Mita Hospital , Tokyo , Japan.
    Objective: Currently, many studies are being performed that focus on the efficacy and safety of the vessel sealing system (VSS) in various fields of surgery. However, in the field of oral cancer surgery, the efficacy and safety of VSS use have not been clarified.

    Methods: One hundred and fifty-one patients underwent oral cancer resection and reconstructive surgery. Read More

    Ten years of active middle ear implantation for sensorineural hearing loss.
    Acta Otolaryngol 2018 May 31:1-8. Epub 2018 May 31.
    a ENT Clinic, NESMOS Department, Medicine and Psychology , Sapienza University , Rome , Italy.
    Objectives: To evaluate long-term benefits of a totally implantable active middle ear implant (AMEI) that has been used in a single implanting center for over 10 years.

    Methods: Forty-one subjects who underwent implantation with an Esteem AMEI during a 10-years period were evaluated on the auditory benefits, as derived from pure tone and speech audiometry tests. The analysis included a comparison with a conventional hearing aid, the problematics related to the battery duration and surgical replacement and, finally, the complication rate. Read More

    Acquired stenosis of the external auditory canal - long-term results and patient satisfaction.
    Acta Otolaryngol 2018 May 31:1-5. Epub 2018 May 31.
    a Department of Otorhinolaryngology , Medical Faculty, Head and Neck Surgery, University of Cologne , Cologne , Germany.
    Background: The surgical treatment of acquired post-inflammatory atresia of the external auditory canal (EAC) is challenging. Based on the long-term surgical experience, a modified split skin graft technique has been established at our clinic.

    Aims/objectives: The aim was to evaluate the clinical and audiological data and patient satisfaction after performing meatoplasty. Read More

    Different cutoffs of the reflux finding score for diagnosing laryngopharyngeal reflux disease should be used for different genders.
    Acta Otolaryngol 2018 May 31:1-7. Epub 2018 May 31.
    a Otolaryngology-Head and Neck Surgery , Southern Medical University Nanfang Hospital , Guangzhou , Guangdong , China.
    Objectives: To assess the differences in Reflux Finding Score (RFS) between the genders and determine the suitable RFS threshold for diagnosing laryngopharyngeal reflux disease (LPRD) in each gender.

    Methods: Asymptomatic volunteers and patients with LPRD, confirmed with an oropharyngeal Dx-pH monitoring system, were included. All study subjects underwent transnasal flexible fiber-optic video laryngoscopy. Read More

    Human papillomavirus (HPV) is absent in branchial cleft cysts of the neck distinguishing them from HPV positive cystic metastasis.
    Acta Otolaryngol 2018 May 15:1-4. Epub 2018 May 15.
    b Department of Clinical Science, Intervention and Technology, Otorhinolaryngology Head and Neck Surgery , Karolinska University Hospital , Stockholm , Sweden.
    Background: Distinguishing branchial cleft cysts (BCCs) from cystic metastases of a human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma (OPSCC) is challenging. Fine needle aspirates (FNAs) from cystic metastasis may be non-representative, while reactive squamous cells from BCC can be atypic. Based on cytology and with the support of HPV DNA positivity many centers treat cystic metastasis oncological and thus patients are spared neck dissection. Read More

    Delayed transmastoid facial nerve decompression surgery in patients with Ramsay-Hunt syndrome presenting with neurophysiologically complete paralysis.
    Acta Otolaryngol 2018 May 15:1-5. Epub 2018 May 15.
    a Department of Otolaryngology Head and Neck Surgery , Kumamoto University Graduate School of Medicine , Kumamoto , Japan.
    Objectives: To determine the efficacy of delayed transmastoid facial nerve decompression in patients with Ramsay Hunt Syndrome (RHS) presenting with complete facial paralysis.

    Methods: Twenty-five RHS patients with complete facial nerve paralysis presenting electroneuronographic (ENoG) degeneration ≥90% underwent transmastoid facial nerve decompression more than 3 weeks after the onset of paralysis. The principal features measured were 12 months pre- and post-operative House-Brackmann (HB) grades and the presence of a direct intraoperative neural response (INR) prior to decompression procedure. Read More

    Effect of intratympanic steroid injection in light cupula.
    Acta Otolaryngol 2018 May 15:1-6. Epub 2018 May 15.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital , Seoul , Korea.
    Objective: To evaluate the effects of intratympanic steroid injection (ITS) in light cupula.

    Methods: A total of 47 patients showing persistent geotropic direction-changing positional nystagmus with null point (light cupula) were randomly classified into three groups: ITS (n = 15), vestibular suppressant (VS, n = 16) and canalith repositioning procedure (CRP, n = 16). Positional nystagmus and dizziness severity by dizziness handicap inventory (DHI) and visual analogue scale (VAS) were conducted before and 3 d and 1 week after first treatment to compare the effect of each treatment. Read More

    Magnesium as an intrinsic component of human otoconia.
    Acta Otolaryngol 2018 May 15:1-4. Epub 2018 May 15.
    b Chemical Physics of Solids , Max Planck Institute , Dresden , Germany.
    Objectives: To investigate morphology changes of artificial otoconia (CGC) in the presence of magnesium during growth under in vitro conditions.

    Methods: Investigating human otoconia by environmental scanning electron microscope and determining their magnesium content by energy-dispersive X-ray microanalysis (EDX). Comparing structural and morphological data of human and artificial otoconia (CGC, CaMg) without and with magnesium substitution (CaMg). Read More

    Categorical perception of lexical tones in native Mandarin-speaking listeners with sensorineural hearing loss.
    Acta Otolaryngol 2018 May 15:1-6. Epub 2018 May 15.
    a Department of Otolaryngology Head and Neck Surgery , Beijing TongRen Hospital, Capital Medical University , Beijing , PR China.
    Background: Categorical perception (CP) of lexical tones was examined in normal hearing (NH) people, but it was unclear whether lexical tones can be perceived categorically in sensorineural hearing loss (SNHL) people.

    Objectives: To explore the characteristic of lexical tone perception in native Mandarin speakers with SNHL.

    Materials And Methods: Three types of continuum (Tone1/Tone2, Tone1/Tone4 and Tone2/Tone3) were constructed and each of them includes 15 stimuli which were resynthesized by applying the pitch-synchronous overlap and add (PSOLA) method implemented in Praat to the same Mandarin syllable, /a/, with a high-level tone produced by a female speaker. Read More

    Familial nonsyndromic hearing loss with incomplete partition type II caused by novel DSPP gene mutations.
    Acta Otolaryngol 2018 May 9:1-6. Epub 2018 May 9.
    a Department of Otolaryngology, Head and Neck Surgery , Institute of Otolaryngology, Chinese PLA General Hospital , Beijing , China.
    Background: Familial nonsyndromic hearing loss (NSHL) with incomplete partition type II (IP-II) is a very rare condition.

    Aims/objectives: To determine the audiological feature, inheritance patterns and genetic etiology of familial NSHL with IP-II in a Chinese family with eight family members.

    Material And Methods: Clinical data were collected from all eight family members, selected deafness genes were sequenced in proband and whole genome sequencing of seven family members was performed. Read More

    HPV-16 viral load in oropharyngeal squamous cell carcinoma using digital PCR.
    Acta Otolaryngol 2018 May 9:1-5. Epub 2018 May 9.
    a Department of Population Health , QIMR Berghofer Medical Research Institute , Brisbane , Australia.
    Conclusions: We did not identify any strong associations between HPV-16 viral load and any of the clinical or lifestyle factors.

    Objective: The epidemiology of oropharyngeal SCC is changing, with an increasing proportion of HPV-positive cases seen in the last decade. It is known that a high viral load is linked to the development of cervical cancer, the relation between viral load and oropharyngeal SCC is less clear. Read More

    Time course of subacute pain after transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma versus traditional bilateral tonsillectomy in adults - a case-control study.
    Acta Otolaryngol 2018 May 9:1-6. Epub 2018 May 9.
    a Department of Otorhinolaryngology , Head and Neck Surgery & Audiology, Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
    Objective: To examine pain after Transoral Robotic Surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC) versus traditional bilateral tonsillectomy in adults.

    Methods: Pain evolvement was assessed in a prospective case-control design of 16 consecutive patients treated with TORS for early stage OPSCC versus 12 patients, who underwent bilateral tonsillectomy on suspicion of malignant disease. The TORS group received an optimized analgesia regime of preoperative oral celecoxib and gabapentin, intra- and postoperative high-dose intravenous dexamethasone, and regular postoperative oral contalgin, gabapentin, celecoxib, paracetamol and rescue morphine. Read More

    Sensory preservation in neck dissection: outcomes of a sub-sternocleidomastoid approach.
    Acta Otolaryngol 2018 Apr 14:1-5. Epub 2018 Apr 14.
    b Department of Otolaryngology - Head and Neck Surgery , National Hospital Organization Kyoto Medical Center , Kyoto , Japan.
    Objective: Cutaneous anesthesia in early postoperative period is common after neck dissection even if the cervical nerve (CN) rootlets are preserved. The aim of this study was to evaluate if the preservation of the terminal branches of CNs using sub-sternocleidomastoid (SCM) approach combined with medially placed skin incision can prevent early postoperative anesthesia.

    Material And Methods: A retrospective chart review was performed on 129 neck dissections in 87 head and neck cancer patients. Read More

    Clinicopathologic analysis of 2736 salivary gland cases over a 11-year period in Southwest China.
    Acta Otolaryngol 2018 Apr 14:1-4. Epub 2018 Apr 14.
    a Department of Oral and Maxillofacial Surgery , Affiliated Stomatology Hospital of Kunming Medical University , Kunming , China.
    Objective: To investigate the epidemiological and clinicopathological characteristics of salivary gland tumors in southwest China in order to provide data for clinical diagnosis and other similar research.

    Methods: Between March 2007 and December 2017, 2736 patients with salivary gland tumors were recruited, the clinical and pathological data were retrospectively analyzed.

    Results: A total of 2736 patients had a ratio of males to females of about 1. Read More

    Auditory brainstem implant in postmeningitis totally ossified cochleae.
    Acta Otolaryngol 2018 Apr 1:1-5. Epub 2018 Apr 1.
    a Department of Otolaryngology , Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo , São Paulo , Brazil.
    Introduction: An auditory brainstem implant (ABI) is an option for auditory rehabilitation in patients with totally ossified cochleae who cannot receive a conventional cochlear implant.

    Objective: To evaluate the outcomes in audiometry and speech perception tests after the implantation of an ABI via the extended retrolabyrinthine approach in patients with postmeningitis hearing loss.

    Materials And Methods: Ten patients, including children and adults, with postmeningitis hearing loss and bilateral totally ossified cochleae received an ABI in a tertiary center from 2009 to 2015. Read More

    Pretreatment lymphocyte-to-monocyte ratio as an independent prognostic factor for hypopharyngeal squamous cell carcinoma.
    Acta Otolaryngol 2018 Apr 1:1-7. Epub 2018 Apr 1.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Eye, Ear, Nose & Throat Hospital, Fudan University , Shanghai , China.
    Objective: The aim of this work was to analyze the clinical characteristics and pretreatment peripheral blood cell counts of patients with hypopharyngeal squamous cell carcinoma (HPSCC) and determine their relationship with clinical outcomes.

    Methods: One hundred ninety-seven patients were eligible for the study. The relationship between survival and pretreatment peripheral absolute neutrophil count (ANC), absolute lymphocyte count (ALC), absolute monocyte count (AMC), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR) were analyzed by one-way analysis of variance, t-test, and univariate and multivariate analysis. Read More

    Expression of aquaporins mRNAs in patients with otitis media.
    Acta Otolaryngol 2018 Apr 1:1-7. Epub 2018 Apr 1.
    a Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine , Kyung Hee University , Seoul , South Korea.
    Objective: This study analyzed the associations between measured levels of aquaporin (AQP) mRNAs and clinical manifestations in patients with various types of otitis media (OM).

    Methods: AQP1, 2, 3, 4, 5, 6, 8, and 10 mRNA levels were assayed by real-time PCR from 57 patients with chronic otitis media (COM), 24 patients with cholesteatomatous otitis media (choleOM), and 82 patients with otitis media with effusion (OME). The relationships of these mRNA levels with the presence of bacteria, the type of hearing loss, and clinical manifestations of OM types were evaluated. Read More

    Estimation of the status of spiral ganglion neurons and Schwann cells in the auditory neural degeneration mouse using the auditory brainstem response.
    Acta Otolaryngol 2018 Jul 19;138(7):603-609. Epub 2018 Mar 19.
    a Department of Otolaryngology - Head and Neck Surgery , Renmin Hospital of Wuhan University , Wuhan , China.
    Conclusion: The auditory brainstem response (ABR) wave I threshold, latency and amplitude are insensitive to spiral ganglion neurons (SGNs) degeneration, but are sensitive to the degeneration of Schwann cells and can estimate the status of Schwann cells in a neural degeneration mouse model. The thorough pre-operative ABR assessment would be helpful in predicting cochlear implant performance.

    Objectives: This study aimed in finding a non-invasive electrophysiological method to evaluate the status of the auditory nerve and the Schwann cells in sensorineural hearing loss (SNHL) and auditory neuropathy (AN) ears, and providing useful information for candidates screening and outcome prediction in cochlear implantation. Read More

    Bimodal benefit for cochlear implant listeners with different grades of hearing loss in the opposite ear.
    Acta Otolaryngol 2018 Mar 19:1-9. Epub 2018 Mar 19.
    a Department of Audiology , ENT-clinic, University of Erlangen-Nürnberg , Erlangen , Germany.
    Objective: To determine speech perception in quiet and noise of adult cochlear implant listeners retaining a hearing aid contralaterally. Second, to investigate the influence of contralateral hearing thresholds and speech perception on bimodal hearing.

    Patients And Methods: Sentence recognition with hearing aid alone, cochlear implant alone and bimodally at 6 months after cochlear implantation were assessed in 148 postlingually deafened adults. Read More

    Canal wall-down procedure with soft posterior meatal wall reconstruction in acquired cholesteatoma: focus on postoperative middle ear status.
    Acta Otolaryngol 2018 Mar 8:1-6. Epub 2018 Mar 8.
    b Department of Otolaryngology Head and Neck Surgery , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama City , Okayama , Japan.
    Objectives: We reviewed surgical results of canal wall-down tympanoplasty (CWDT) with soft posterior meatal wall reconstruction (SWR) for acquired cholesteatoma (AC), and identified factors associated with surgical outcomes.

    Methods: Results from 119 ears with AC (pars flaccida, n = 99; pars tensa, n = 20) that underwent CWDT with SWR were retrospectively reviewed. We defined postoperative balloon-like retraction (PBR) with web formation, which needed reoperation to clean accumulated cerumen, as postoperative deep retraction pocket (PDRP). Read More

    A rational approach to identifying newborns with hearing loss caused by congenital cytomegalovirus infection by dried blood spot screening.
    Acta Otolaryngol 2018 Mar 7:1-5. Epub 2018 Mar 7.
    a Department of Otorhinolaryngology , Shinshu University School of Medicine , Matsumoto , Japan.
    Objective: Congenital cytomegalovirus (cCMV) infection is the most common congenital infection, with the majority of infected newborns having no detectable signs. The aim of this study was to examine the accuracy of our newly developed DBS-based assay as an appropriate mass screening method for cCMV infection.

    Methods: Between May 2011 and October 2016, newborns delivered at six hospitals in Nagano Prefecture, Japan were enrolled prospectively. Read More

    Assessment of lingual sentinel lymph nodes metastases using dual-modal indirect CT/MR lymphography with gold-gadolinium-based nanoprobes in a tongue VX carcinoma model.
    Acta Otolaryngol 2018 Mar 7:1-7. Epub 2018 Mar 7.
    a Departments of Otolaryngology-Head and Neck Surgery , Fudan University , Shanghai , China.
    Objective: To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX carcinoma model.

    Materials And Methods: Seventeen rabbits were used to establish a metastatic cervical lymph node model by implanting VX carcinoma suspension into the ventral tongue muscle. CT and MR images were acquired one hour after Gd-Au PENPs injection into the tongue submucosa bilaterally, on 1w (n = 4), 2w (n = 6) and 3w (n = 7) tumour-bearing rabbits after carcinoma transplantation. Read More

    Contribution of intratympanic steroids in the primary treatment of sudden hearing loss.
    Acta Otolaryngol 2018 Jul 7;138(7):648-651. Epub 2018 Mar 7.
    a Otorhinolaryngology Department , Istanbul Training and Research Hospital , Istanbul , Turkey.
    Objective: The primary objective is to investigate the contribution of intratympanic steroids in the primary treatment of idiopathic sudden sensorineural hearing loss (ISSNHL). The secondary objective is to compare methylprednisolone (MP) and dexamethasone in terms of their effectiveness and injection-site pain.

    Methods: Two hundred and four patients with ISSNHL, 144 patients underwent systemic steroid therapy (SST) alone and 60 patients underwent combined therapy (CT). Read More

    l-N-acetylcysteine protects outer hair cells against TNFα initiated ototoxicity in vitro.
    Acta Otolaryngol 2018 Mar 7:1-9. Epub 2018 Mar 7.
    a Department of Otolaryngology, Hearing Research Laboratory , Miller School of Medicine University of Miami , Miami , FL , USA.
    Objective: The present study is aimed at determining the efficacy and exploring the mechanisms by which l-N-acetylcysteine (l-NAC) provides protection against tumor necrosis factor-alpha (TNFα)-induced oxidative stress damage and hair cell loss in 3-day-old rat organ of Corti (OC) explants. Previous work has demonstrated a high level of oxidative stress in TNFα-challenged OC explants. TNFα can potentially play a significant role in hair cell loss following an insult to the inner ear. Read More

    Assessment of the efficacy of a local steroid rescue treatment administered 2 days after a moderate noise-induced trauma in guinea pig.
    Acta Otolaryngol 2018 Jul 5;138(7):610-616. Epub 2018 Mar 5.
    a Sorbonne Université, Université Pierre et Marie Curie Paris 6, Inserm, Unité "Réhabilitation Chirurgicale Mini-Invasive et Robotisée de l'Audition" , Paris , France.
    Objectives: Intratympanic injection of corticosteroids membrane after noise-induced hearing loss is an accepted alternative to general administration. We investigated the effect on hearing of a hyaluronic acid gel with liposomes loaded with dexamethasone (DexP) administered into the middle ear.

    Methods: An acute acoustic trauma was performed to 13 guinea pigs for a period of 1 h on Day -2. Read More

    Distortion product otoacoustic emission together with tympanometry for assessing otitis media with effusion in children.
    Acta Otolaryngol 2018 Mar 5:1-4. Epub 2018 Mar 5.
    b Department of Otolaryngology, Head and Neck Surgery , Shanghai Children's Hospital, Shanghai Jiao Tong University , Shanghai , China.
    Objective: To investigate the diagnostic value of distortion product otoacoustic emission (DPOAE) together with tympanometry in assessing otitis media with effusion in children.

    Methods: Three hundred and thirty-nine patients, who were diagnosed with obstructive sleep apnea-hypopnea syndrome (OSAHS) and prepared to undergo adenotonsillectomy and had a unilateral or bilateral type 'B' or 'C' tympanogram were enrolled in this study. Patients were divided into the following four groups: Group 1, type 'B' tympanogram with positive DPOAE; Group 2, type 'B' tympanogram with negative DPOAE; Group 3, type 'C' tympanogram with positive DPOAE and Group 4, type 'C' tympanogram with negative DPOAE. Read More

    A new classification of vocal fold leukoplakia by morphological appearance guiding the treatment.
    Acta Otolaryngol 2018 Jun 5;138(6):584-589. Epub 2018 Mar 5.
    a Department of Otorhinolaryngology-Head and Neck Surgery (Shanghai Key Clinical Disciplines of Otorhinolaryngology) , Eye, Ear, Nose and Throat Hospital of Fudan University , Shanghai , People's Republic of China.
    Objective: To provide a reference for classification and treatment of vocal cords leukoplakia.

    Methods: 640 cases of patients with vocal cords leukoplakia were divided into three groups based on the appearances. There were respectively 81 smooth flat lesions, 155 smooth hypertrophy lesions and 13 rough lesions were treated with conservative methods and 26, 153 and 212 cases were resected surgically for biopsy. Read More

    Variation in prognosis of early laryngeal carcinoma after different types of cordectomy with transoral laser microsurgery.
    Acta Otolaryngol 2018 Mar 5:1-5. Epub 2018 Mar 5.
    a Department of Otorhinolaryngology Head and Neck Surgery , Beijing Tongren Hospital, Capital Medical University , Beijing , PR China.
    Background: The lack of standardized treatment is problematic in laser surgery for laryngeal cancer, and may result in an increased recurrence rate. This study analyzed the prognosis of early laryngeal carcinoma after different types of cordectomy with laser surgery.

    Methods: A cohort of 818 patients with stage Tis or T1 primary early glottic squamous cell carcinoma treated with CO laser surgery was retrospectively analyzed. Read More

    Threshold monitoring of intraoperative auditory steady-state responses for ossiculoplasty surgery.
    Acta Otolaryngol 2018 Jul 5;138(7):625-632. Epub 2018 Mar 5.
    a Department of Otorhinolaryngology - Head and Neck Surgery , Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing , PR China.
    Objective: The objective of this study is to establish a reliable intraoperative auditory threshold monitoring system for ossiculoplasty surgery.

    Design: The chirp signal of self-designed sound field earphone (SFE) was calibrated physically and psychophysically. The interaural attenuation of the SFE was tested in patients with unilateral complete deafness and contralateral normal hearing (10 patients). Read More

    Intralesional bleomycin A5 injection for the treatment of nasal polyps through inducing apoptosis.
    Acta Otolaryngol 2018 May 28;138(5):475-482. Epub 2018 Feb 28.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , Guangdong , People's Republic of China.
    Conclusion: An intralesional bleomycin A5 (BLE) injection might be used as an alternative therapy for eosinophilic-type nasal polyps (NPs). BLE-induced apoptosis might play an important role in shrinkage of NPs.

    Objectives: The aim of this study is to determine the effect and explore the possible role of apoptosis in shrinkage of NPs. Read More

    Transmastoid implantability of an active transcutaneous bone conduction implant in adults with regard to the underlying pathology: a radiological simulation study.
    Acta Otolaryngol 2018 Jun 23;138(6):530-536. Epub 2018 Feb 23.
    a Department of Otolaryngology, Head and Neck Surgery , Ruhr University Bochum, St. Elisabeth-Hospital , Bochum , Germany.
    Objectives: To compare the feasibility of transmastoid implantation of an active transcutaneous bone conduction device (BCD) in the most important pathologies of the temporal bone and the impact of implant lifts in adulthood.

    Methods: First, clinical predominant pathologies for implantation of this BCD were evaluated by a literature review. Then, high-resolution CT of 240 temporal bones with neuro-otologic diseases (NOD), chronic otitis media (COM), or cholesteatoma, respectively, were investigated regarding their implantability, using a radiological simulation program. Read More

    Reflux symptom index and reflux finding score in 91 asymptomatic volunteers.
    Acta Otolaryngol 2018 Jul 22;138(7):659-663. Epub 2018 Feb 22.
    b Department of Gastroenterology , Fujian Provincial Clinical College of Fujian Medical University , Fuzhou , China.
    Background: The primary goal of this study was to investigating the symptoms, in addition to the reflux-related laryngopharynx inflammation performance of asymptomatic, volunteers, and verified the 'normal point'.

    Methods: A total of 91 asymptomatic subjects were recruited for this cross-sectional study between March 2016 and September 2016. Participants completed the reflux symptom index (RSI) assessment and underwent laryngostroboscopic examination using a rigid endoscope. Read More

    Health-related quality of life in hearing-impaired adolescents and children.
    Acta Otolaryngol 2018 Jul 22;138(7):652-658. Epub 2018 Feb 22.
    a Department of Otorhinolaryngology-Head and Neck Surgery, Hearing Clinic , Helsinki University Hospital , Helsinki , Finland.
    Objective: To evaluate health-related quality of life (HRQoL) in hearing-impaired adolescents and children and to compare it with that of hearing individuals.

    Study Design And Setting: Hearing-impaired adolescents and children were recruited to the study during their annual control visit to the Hearing Clinic of Helsinki University Hospital. They filled in a HRQoL questionnaire, either the 16-dimensional 16D (adolescents aged 12-17 years) or the 17-dimensional 17D (children aged 7-11 years). Read More

    Definitive re-irradiation using intensity-modulated radiation therapy in cancers of the head and neck, focusing on rare tumors.
    Acta Otolaryngol 2018 Feb 22:1-9. Epub 2018 Feb 22.
    a Miyakojima IGRT Clinic , Miyakojimahondori, Miyakojima-ku , Osaka , Japan.
    Purpose: To analyze the outcomes following re-irradiation for local recurrence of rare head and neck tumors.

    Material And Methods: We retrospectively analyzed 11 patients who had received intensity-modulated radiation therapy (IMRT) for recurrent tumors in the head and neck except for laryngopharynx.

    Results: Primary tumor sites included the maxillary sinus, nasal cavity, and external ear canal in six, three, and two patients, respectively. Read More

    Long-term results of atresiaplasty in patients with congenital aural atresia.
    Acta Otolaryngol 2018 Jul 9;138(7):621-624. Epub 2018 Feb 9.
    a Department of Otorhinolaryngology , Tampere University Hospital, and School of Medicine, University of Tampere , Tampere , Finland.
    Objectives: To evaluate long-term benefits of atresiaplasty on hearing and the impact of surgery on quality of life (QoL) in congenital aural atresia (CAA) patients.

    Methods: We evaluated the long-term hearing results, the impact of atresiaplasty on QoL, the meatal diameter of the operated ear canal, and the cumulative number of post-operative hospital visits in 14 CAA patients, on average, 12 years (range: 4-17 years) post-operatively.

    Results: The mean preoperative pure tone average (PTA) was 61 dB HL. Read More

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