8,530 results match your criteria Acta Ophthalmologica[Journal]


Optos wide-field imaging versus conventional camera imaging in Danish patients with type 2 diabetes.

Acta Ophthalmol 2019 Apr 15. Epub 2019 Apr 15.

Steno Diabetes Center Copenhagen, Gentofte, Denmark.

Purpose: Diabetic retinopathy (DR) screening methods are costly, requiring specialized personnel and patient mydriasis. The Optos apparatus can be operated by nonspecialists and provides ultra-wide-field imaging, with 200° views of the retina in a single image. We compared DR grading obtained from Optos imaging with DR grading from conventional Topcon imaging. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14118
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http://dx.doi.org/10.1111/aos.14118DOI Listing
April 2019
1 Read

Fundus disease in today's China.

Authors:
Xun Xu

Acta Ophthalmol 2019 May;97(3):231

Shanghai, China.

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http://dx.doi.org/10.1111/aos.14111DOI Listing

Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

UCL Institute of Ophthalmology, London, UK.

Purpose: To investigate the progression characteristics of ellipsoid zone (EZ) loss in eyes with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements, and their relevance for visual acuity.

Methods: Participants were selected from the MacTel Study cohort. Linear and area measurements of EZ loss were performed in Spectral-Domain Optical Coherence Tomograph (SD-OCT) volume scans. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14110
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http://dx.doi.org/10.1111/aos.14110DOI Listing
April 2019
10 Reads

Reading deficits in diabetic patients treated with panretinal photocoagulation and good visual acuity.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.

Purpose: Patients with proliferative diabetic retinopathy (PDR) treated with panretinal photocoagulation (PRP) can have abnormal visual functioning that may be missed by Snellen visual acuity alone. We investigated reading deficits in patients treated with PRP for PDR using the Minnesota reading (MNREAD) test.

Methods: Thirty patients treated with PRP and 15 controls underwent best-corrected visual acuity (BCVA), the MNREAD, frequency doubling perimetry (FDP), and fundus photography. Read More

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http://dx.doi.org/10.1111/aos.14097DOI Listing
April 2019
1 Read

Cost-effectiveness analysis in a randomized trial of late in-the-bag intraocular lens dislocation surgery: repositioning versus exchange.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.

Purpose: To compare the cost-effectiveness of two operation methods for late in-the-bag intraocular lens (IOL) dislocation.

Methods: In this randomized clinical trial, 104 patients were randomly assigned to IOL repositioning by scleral suturing (n = 54) or IOL exchange with a retropupillary iris-claw lens (n = 50). A cost-effectiveness analysis (CEA) was performed in conjunction with previously published 6-month efficacy and safety results. Read More

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http://dx.doi.org/10.1111/aos.14108DOI Listing

Incidence and prevalence of keratoconus in Denmark - an update.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

Purpose: To describe the annual incidence rate of keratoconus in Denmark 1995-2015 and prevalence of keratoconus in the National Danish Patient Register 1977-2015.

Methods: All patients diagnosed with keratoconus in the National Danish Patient Register 1977-2015 were included in the study. The annual incidence rates and the overall prevalence of diagnosed keratoconus in the register were calculated using life tables from the general Danish population. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14082
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http://dx.doi.org/10.1111/aos.14082DOI Listing
April 2019
1 Read

Quantitative evaluation of primary retinitis pigmentosa patients using colour Doppler flow imaging and optical coherence tomography angiography.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, China.

Purpose: To find the potential relation between changes in retinal large vessels and terminal vessels using colour Doppler flow imaging (CDFI) and optical coherence tomography angiography (OCTA) and to compare the respective advantages of CDFI and OCTA in evaluating vascular changes in retinitis pigmentosa (RP) patients.

Methods: A prospective series of case study was conducted to enrol RP patients and age-matched controls, who were, respectively, imaged by CDFI and OCTA. Repeatability and reproducibility of both CDFI and OCTA were performed among healthy volunteers. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14047
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http://dx.doi.org/10.1111/aos.14047DOI Listing
April 2019
2 Reads

Fluorometholone modulates gene expression of ocular surface mucins.

Acta Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, CA, USA.

Purpose: Mucins are vital to keep the ocular surface hydrated. Genes encoding for mucins contain a glucocorticoid response element. The purpose of this study was to evaluate the effect of fluorometholone, a glucocorticoid receptor agonist used in the management of dry eye, on the gene expression of conjunctival and corneal epithelial cell mucins. Read More

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http://dx.doi.org/10.1111/aos.14113DOI Listing
April 2019
1 Read

A human amniotic membrane plug to repair retinal detachment associated with large macular tear.

Acta Ophthalmol 2019 Apr 6. Epub 2019 Apr 6.

Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To describe a surgical technique, using a human amniotic membrane (hAM) plug, in two cases of retinal detachment with a large macular tear.

Methods: Surgical technique description with surgical video. A 23-gauge pars plana vitrectomy with peripheral retinectomy was performed. Read More

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http://dx.doi.org/10.1111/aos.14109DOI Listing
April 2019
1 Read

Prophylactic treatment of intraocular pressure elevation after uncomplicated cataract surgery in nonglaucomatous eyes - a systematic review.

Acta Ophthalmol 2019 Apr 2. Epub 2019 Apr 2.

Department of Ophthalmology, Odense University Hospital, Odense, Denmark.

The purpose of this systematic review was to evaluate the literature regarding prophylactic treatment of intraocular pressure (IOP) elevation after uncomplicated cataract surgery to provide an evidence-based guideline for cataract surgeons. The relevant literature was identified in EMBASE and PubMed. The risk of bias was assessed according to the 'Cochrane Handbook for Systematic Reviews of Interventions' and the ROBINS-I tool. Read More

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http://dx.doi.org/10.1111/aos.14092DOI Listing
April 2019
3 Reads

The combination of whole-exome sequencing and clinical analysis allows better diagnosis of rare syndromic retinal dystrophies.

Acta Ophthalmol 2019 Mar 29. Epub 2019 Mar 29.

Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Purpose: To identify the accurate clinical diagnosis of rare syndromic inherited retinal diseases (IRDs) based on the combination of clinical and genetic analyses.

Methods: Four unrelated families with various autosomal recessive syndromic inherited retinal diseases were genetically investigated using whole-exome sequencing (WES).

Results: Two affected subjects in family MOL0760 presented with a distinctive combination of short stature, developmental delay, congenital mental retardation, microcephaly, facial dysmorphism and retinitis pigmentosa (RP). Read More

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http://dx.doi.org/10.1111/aos.14095DOI Listing
March 2019
3 Reads

Phacotrabeculectomy using collagen matrix implant (Ologen ) versus mitomycin C: a prospective randomized controlled trial.

Acta Ophthalmol 2019 Mar 29. Epub 2019 Mar 29.

Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.

Purpose: To compare the efficacy and safety of collagen matrix implant (Ologen ; OLO) with mitomycin C (MMC) in phacotrabeculectomy.

Methods: Prospective, single-centre, nonblinded, randomized controlled trial. A total of 53 eyes of 45 patients were enrolled in the study protocol with 27 eyes randomly assigned to OLO and 26 to MMC. Read More

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http://dx.doi.org/10.1111/aos.14102DOI Listing
March 2019
1 Read

Investigating the neuroprotective effect of Copolymer-1 in acute primary angle closure - Interim report of a randomized placebo-controlled double-masked clinical trial.

Acta Ophthalmol 2019 Mar 27. Epub 2019 Mar 27.

Singapore Eye Research Institute and Singapore National Eye Center, Singapore City, Singapore.

Purpose: To investigate the neuroprotective effect of Copolymer-1 (Cop-1) in patients with acute primary angle closure (APAC) in a randomized double-masked controlled trial.

Methods: After initial medical management, APAC patients were randomized to receive either subcutaneous Cop-1 or placebo within 24 hr and at 1 week. After laser peripheral iridotomy (LPI), subjects underwent serial visual field (VF) tests and retinal nerve fibre layer (RNFL) thickness measurements with spectral-domain optical coherence tomography. Read More

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http://dx.doi.org/10.1111/aos.14099DOI Listing
March 2019
2 Reads
2.844 Impact Factor

Short-term effect on the ocular circulation induced by unilateral intravitreal injection of aflibercept in age-related maculopathy.

Acta Ophthalmol 2019 Mar 27. Epub 2019 Mar 27.

Department for Ophthalmology, Kepler University Hospital, Johannes Kepler University, Linz, Austria.

Purpose: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) is the standard treatment for neovascular age-related macular degeneration (AMD). As VEGF is a physiological key player for regulating retinal vascular tone, questions have been raised whether the application of anti-VEGF could induce alterations in ocular perfusion.

Methods: The study included 20 eyes from 20 Caucasian patients with unilateral neovascular AMD and 20 fellow eyes. Read More

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http://dx.doi.org/10.1111/aos.14098DOI Listing

Prescription pattern of ocular hypotensive drugs in Portugal and its comparison with the European guidelines - PEM Study.

Acta Ophthalmol 2019 Mar 27. Epub 2019 Mar 27.

Vision Sciences Study Centre, CECV, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14103
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http://dx.doi.org/10.1111/aos.14103DOI Listing
March 2019
3 Reads

A comparison of the lateral tarsal strip with everting sutures and the Quickert procedure for involutional entropion.

Acta Ophthalmol 2019 Mar 27. Epub 2019 Mar 27.

Department of Ophthalmology, Asklepios Clinic Barmbek, Hamburg, Germany.

Background/aims: To provide evidence of statistically significant difference in the surgical outcome of the lateral tarsal strip with everting sutures (LTS + ES) versus the Quickert procedure (QP) in the treatment of involutional entropion.

Methods: In a prospective randomized comparative trial, 66 eyelids of 52 patients with primary involutional lower eyelid entropion were recruited. Thirty-six eyelids were randomized to QP, and 30 eyelids were randomized to LTS + ES. Read More

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http://dx.doi.org/10.1111/aos.14093DOI Listing

Topical levofloxacin, nepafenac and prednisolone acetate medication after cataract surgery in the biggest tertiary eye hospital in Finland during 2015-2018.

Acta Ophthalmol 2019 Mar 27. Epub 2019 Mar 27.

Unit of Administration, Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1111/aos.14091DOI Listing

Eye Injuries across history and the evolution of eye protection.

Acta Ophthalmol 2019 Mar 25. Epub 2019 Mar 25.

Save Sight Institute, The University of Sydney, Sydney, NSW, Australia.

Purpose: To describe the history of eye injuries and the consequent evolution of eye protection.

Methods: A comprehensive search of Medline and the grey literature using the terms 'ocular trauma' and 'eye protection' or 'injury prevention' and 'history'. References were used to identify other relevant publications. Read More

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http://dx.doi.org/10.1111/aos.14086DOI Listing
March 2019
2.844 Impact Factor

Semi-automated quantification of geographic atrophy with blue-light autofluorescence and spectral-domain optical coherence tomography: a comparison between the region finder and the advanced retinal pigment epithelium tool in the clinical setting.

Acta Ophthalmol 2019 Mar 24. Epub 2019 Mar 24.

Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

Purpose: To compare inter- and intraobserver reliability and intermodality agreement on quantification of geographic atrophy, using two routinely available quantification tools, based on blue-light fundus autofluorescence (BAF) and spectral-domain optical coherence tomography (SD-OCT).

Methods: Quantifications of atrophic lesions within the central 5 mm of 30 eyes from 30 patients (mean age: 76.1 years) were independently performed by two clinicians on BAF images using the region finder (RF; Heidelberg Engineering) and on SD-OCT using the advanced retinal pigment epithelium tool (ARPET; Carl Zeiss Meditec) at baseline and follow-up (mean interval: 336 days). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14085
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http://dx.doi.org/10.1111/aos.14085DOI Listing
March 2019
3 Reads

The 'pitchfork sign' on optical coherence tomography in a case of acute syphilitic posterior placoid chorioretinitis.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, Zealand University Hospital, Naestved, Denmark.

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http://dx.doi.org/10.1111/aos.14094DOI Listing

Diurnal variations in flow density measured using optical coherence tomography angiography and the impact of heart rate, mean arterial pressure and intraocular pressure on flow density in primary open-angle glaucoma patients.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, University of Muenster Medical Centre, Muenster, Germany.

Purpose: To determine the diurnal variations in peripapillary and macular flow density (FD), as measured using optical coherence tomography angiography (OCTA) and to elaborate on the relationship between diurnal FD, circulatory parameters and intraocular pressure (IOP) variations in primary open-angle glaucoma (POAG).

Methods: Forty eyes of 40 POAG patients were drawn into this cross-sectional study. The retinal microvasculature of the macula (superficial and deep layers) and optic nerve [radial peripapillary capillary (RPC)] was examined by OCTA (AngioVue , Optovue). Read More

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http://dx.doi.org/10.1111/aos.14089DOI Listing

Long-term prevention of capsular opacification after lens-refilling surgery in a rabbit model.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, University of Rostock, Rostock, Germany.

Purpose: To reduce capsular opacification by a peri-surgical treatment of the lens capsule with drugs in an in vivo rabbit model. Lens-refilling surgery is a potential therapeutic intervention to treat patients with a cataract lens. The lens material is replaced with an injectable (bio)polymer that retains the natural mechanical and optical lens properties, therewith allowing accommodation. Read More

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http://dx.doi.org/10.1111/aos.14096DOI Listing
March 2019
4 Reads

Quantitative choriocapillaris evaluation in intermediate age-related macular degeneration by swept-source optical coherence tomography angiography.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Eye Clinic, University Hospital Maggiore della Carita', Novara, Italy.

Purpose: To investigate choriocapillaris (CC) perfusion, by evaluating flow voids (FV), in eyes with intermediate age-related macular degeneration (iAMD) using swept-source optical coherence tomography angiography (SS-OCT-A).

Methods: Patients with bilateral or unilateral iAMD and normal controls underwent SS-OCT and OCT-A examination. Choriocapillaris (CC) FVs were quantitatively assessed on OCT-A images using matlab (version 2017b; MathWorks, Natick, MA, USA), after a preprocessing aimed at compensating for CC attenuation artefacts. Read More

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http://dx.doi.org/10.1111/aos.14088DOI Listing

Sub-Tenon depository triamcinolone and glycaemic management in diabetic patients.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Institute of Ocular Pharmacology, School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14100
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http://dx.doi.org/10.1111/aos.14100DOI Listing
March 2019
9 Reads

Effect of intravitreal conbercept treatment on the expression of Long Noncoding RNAs and mRNAs in Proliferative Diabetic Retinopathy Patients.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Eye Center of Shandong University, The Second Hospital of Shandong University, Jinan, People's Republic of China.

Purpose: To evaluate the effect of conbercept on the expression of long noncoding RNAs (lncRNAs) and mRNAs in the fibrovascular membranes of proliferative diabetic retinopathy (PDR) patients.

Methods: Twenty patients, diagnosed with PDR, who underwent pars plana vitrectomy (PPV), were recruited for this study. Ten patients were treated for PPV alone (Control Group), and the others received conbercept injections before PPV (Treated Group). Read More

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http://dx.doi.org/10.1111/aos.14083DOI Listing
March 2019
1 Read

Evaluation of retinal nonperfusion in branch retinal vein occlusion using wide-field optical coherence tomography angiography.

Acta Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Yamadaoka, Japan.

Purpose: To characterize wide-field optical coherence tomography angiography (OCTA) features of retinal nonperfusion in eyes with branch retinal vein occlusion (BRVO).

Methods: Automated scanning of five 12 × 12-mm areas of swept-source OCTA and wide-field fluorescein angiography (FA) images was performed in a consecutive case series of 27 eyes in 27 patients with BRVO in this institutional cross-sectional study. The correlation between the areas of retinal nonperfusion detected by both examinations was assessed. Read More

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http://dx.doi.org/10.1111/aos.14087DOI Listing

Transscleral sutureless intraocular lens versus retropupillary iris-claw lens fixation for paediatric aphakia without capsular support: a randomized study.

Acta Ophthalmol 2019 Mar 18. Epub 2019 Mar 18.

Department of Ophthalmology, Cairo University Hospital, Cairo, Egypt.

Purpose: To compare results of sutureless transscleral intraocular lens (IOL) fixation to retropupillary iris-claw lens implantation in cases of paediatric aphakia without capsular support.

Methods: Thirty eyes of children with insufficient capsular support for IOL implantation were randomized to undergo sutureless transscleral IOL fixation or iris-claw lens fixation. The primary outcome was best-corrected visual acuity (BCVA). Read More

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http://dx.doi.org/10.1111/aos.14090DOI Listing
March 2019
1 Read

Amphiregulin and ocular axial length.

Acta Ophthalmol 2019 May 12;97(3):e460-e470. Epub 2019 Mar 12.

Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany.

Purpose: To assess the potential role of amphiregulin as messenger molecule in ocular axial elongation.

Methods: The experimental study included guinea pigs (total n = 78) (age: 3-4 weeks) which underwent bilateral lens-induced myopization and received 15 days later three intraocular injections in weekly intervals of amphiregulin antibody (doses:5 μg, 10 μg, 20 μg) into their right eyes, and three phosphate-buffered saline injections into their left eyes; and guinea pigs without lens-induced myopization and which received three unilateral intraocular injections of amphiregulin antibody (dose: 20 μg) or amphiregulin (doses: 1 ng; 10 ng; 20 ng) into their right eyes, and three phosphate-buffered saline injections into their left eyes. Seven days later, the animals were sacrificed. Read More

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http://doi.wiley.com/10.1111/aos.14080
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http://dx.doi.org/10.1111/aos.14080DOI Listing
May 2019
17 Reads

Children with congenital and childhood cataract require frequent follow-up visits and examinations in general anaesthesia: considerations for the strain on families.

Acta Ophthalmol 2019 Mar 12. Epub 2019 Mar 12.

Department of Ophthalmology, Rigshospitalet-Glostrup, Glostrup, Denmark.

Background: Children with cataract require frequent monitoring to detect complications, adjust refractive correction and treat amblyopia. This is time consuming for the families. The aim of the study was to evaluate how often children with cataract are seen as outpatients or under general anaesthesia during the first 7 years of life. Read More

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http://dx.doi.org/10.1111/aos.14081DOI Listing

Retinal vascular oxygen saturation increases after cardiac surgery.

Acta Ophthalmol 2019 Mar 7. Epub 2019 Mar 7.

Department of Ophthalmology, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.1111/aos.14084DOI Listing
March 2019
1 Read

Retinal oximetry in normal and amblyopic children: a pilot study.

Acta Ophthalmol 2019 Mar 7. Epub 2019 Mar 7.

University Eye Clinic Maastricht, Maastricht, the Netherlands.

Purpose: To study the retinal vascular oxygen saturation in amblyopic eyes and compare them to unaffected fellow eyes and eyes of normal subjects.

Methods: A total of 32 amblyopic, 24 normal and 13 fellow eyes of patients below age of 18 were enrolled in this prospective observation study. Retinal oximetry was performed using the Oxymap T1 retinal oximeter. Read More

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http://dx.doi.org/10.1111/aos.14075DOI Listing

Macular vascular circulation and retinal oxygen saturation changes for idiopathic macular epiretinal membrane after vitrectomy.

Acta Ophthalmol 2019 May 7;97(3):296-302. Epub 2019 Mar 7.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To investigate the postoperative changes in retinal-choroidal blood flow area and retinal vascular oxygen saturation among patients with idiopathic macular epiretinal membranes (iERMs).

Methods: This study prospectively included 24 eyes of 24 consecutive patients who underwent vitrectomy for iERMs. The flow area of choriocapillary layer, retinal superficial capillary plexuses (SCPs) and retinal deep capillary plexuses (DCPs) were performed using optical coherence tomography angiography with angiovue prototype software, and retinal vascular oxygen saturation was measured using retinal oximeter with the built-in software. Read More

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http://dx.doi.org/10.1111/aos.14066DOI Listing
May 2019
2.844 Impact Factor

Retinal vasodilatation in the affected eye but reduced pressure autoregulation of both eyes in unilateral Coats' disease.

Acta Ophthalmol 2019 Mar 6. Epub 2019 Mar 6.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

Background: Coats' disease is characterized by vascular hyperpermeability, oedema and accumulation of exudates related to impairment of retinal vascular function. The background for the development of the disease is unknown, but it is likely that the study of diameter changes of retinal vessels may contribute to understanding the pathophysiology of the disease.

Methods: In seven patients with unilateral Coats' disease (mean age = 34. Read More

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http://dx.doi.org/10.1111/aos.14073DOI Listing
March 2019
1 Read

Feasibility of support vector machine learning in age-related macular degeneration using small sample yielding sparse optical coherence tomography data.

Acta Ophthalmol 2019 Mar 6. Epub 2019 Mar 6.

OCTlab, Department of Ophthalmology, University of Basel, Basel, Switzerland.

Purpose: A retrospective pilot study is conducted to demonstrate the utility of a novel support vector machine learning (SVML) algorithm in a small three-dimensional (3D) sample yielding sparse optical coherence tomography (spOCT) data for the automatic monitoring of neovascular (wet) age-related macular degeneration (wAMD).

Methods: From the anti-vascular endothelial growth factor injection database, 588 consecutive pairs of OCT volumes (57.624 B-scans) were selected in 70 randomly chosen wAMD patients treated with ranibizumab. Read More

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http://dx.doi.org/10.1111/aos.14055DOI Listing
March 2019
1 Read

Retinal oximetry in branch retinal vein occlusion.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Purpose: To measure retinal oxygen saturation (SO ) in eyes with branch retinal vein occlusion (BRVO).

Methods: Retinal oximetry was performed using the Oxymap T1 retinal oximeter in 50 eyes (50 patients) with resolved BRVO. SO was calculated in each major retinal artery and vein in four quadrants. Read More

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http://dx.doi.org/10.1111/aos.14070DOI Listing
February 2019
4 Reads

Development and validation of a multiple-choice questionnaire-based theoretical test in direct ophthalmoscopy.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark.

Purpose: Direct ophthalmoscopy can reveal systemic, neurologic and ophthalmic conditions, but is poorly mastered among young physicians. A theoretical test is needed to measure effect of educational interventions. We developed and gathered validity evidence for a multiple-choice questionnaire (MCQ)-based theoretical test in direct ophthalmoscopy. Read More

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http://dx.doi.org/10.1111/aos.14065DOI Listing
February 2019
4 Reads

Changes in microchip position after implantation of a subretinal vision prosthesis in humans.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Institute for Ophthalmic Research, University Eye Hospital, Center for Ophthalmology, Eberhard Karls University, Tuebingen, Germany.

Purpose: Retinal prosthetic devices have been developed to partially restore very low vision in legally blind patients with end-stage hereditary retinal dystrophies. Subretinal implants, unlike epiretinal implants, are not fixated by a tack. The aim of this study was to assess and analyse possible changes over time in the subretinal position of the RETINA IMPLANT Alpha IMS and Alpha AMS (ClinicalTrials. Read More

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http://doi.wiley.com/10.1111/aos.14077
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http://dx.doi.org/10.1111/aos.14077DOI Listing
February 2019
8 Reads

Aminobisphosphonate-associated orbital and ocular inflammatory disease.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Division of Ophthalmology, Tel-Aviv Sourasky Medical Center, Affiliated to Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Purpose: Aminobisphosphonates may cause orbital/ocular inflammation. Awareness of the clinical presentation and disease course is crucial. The purpose of this study was to analyse demographics, clinical presentation, disease course and treatment of aminobisphosphonate-associated orbital/ocular inflammation in a large series of patients. Read More

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http://dx.doi.org/10.1111/aos.14063DOI Listing
February 2019
1 Read

Endophthalmitis in Oslo, Norway.

Acta Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.

Purpose: To study the incidence, aetiology, pathogenic causes, treatment and visual outcomes of endophthalmitis (EO) at the Department of Ophthalmology, Oslo University Hospital (OUS), Norway.

Methods: Retrospective registry study. Medical records of all EO patients treated at OUS over a 2-year period were reviewed. Read More

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http://dx.doi.org/10.1111/aos.14028DOI Listing
February 2019
2 Reads

Neutrophil-to-lymphocyte ratio in age-related macular degeneration: a systematic review and meta-analysis.

Acta Ophthalmol 2019 Feb 27. Epub 2019 Feb 27.

Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark.

Age-related macular degeneration (AMD) is aetiologically linked to immunological ageing and dysfunction. One aspect of this is the altered neutrophil-to-lymphocyte ratio (NLR), which in other domains have been associated with inflammation and angiogenesis, and therefore investigated in patients with AMD in several papers. In this systematic review and meta-analysis, we summarize findings in patients with AMD in relation to NLR, both qualitatively and quantitatively. Read More

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http://dx.doi.org/10.1111/aos.14072DOI Listing
February 2019
2 Reads

Quantitative analysis of retinal and choroid capillary ischaemia using optical coherence tomography angiography in type 2 diabetes.

Acta Ophthalmol 2019 May 27;97(3):240-246. Epub 2019 Feb 27.

Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.

Purpose: To perform a quantitative analysis of retinal and choroid capillary ischaemia in diabetic patients by using optical coherence tomography angiography (OCTA).

Methods: A total of 97 type 2 diabetic patients and 48 controls were included in this cross-sectional study. Diabetic patients without diabetic retinopathy (DR) were categorized as no DR (NDR) group; DR was classified into mild non-proliferative diabetic retinopathy (NPDR), moderate NPDR, severe NPDR and proliferative diabetic retinopathy (PDR). Read More

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http://dx.doi.org/10.1111/aos.14076DOI Listing
May 2019
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Incidence of retinal artery occlusion following intravitreal antivascular endothelial growth factor injections.

Acta Ophthalmol 2019 Feb 27. Epub 2019 Feb 27.

The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/aos.14058DOI Listing
February 2019
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Evaluation of selective laser trabeculoplasty as an intraocular pressure lowering option.

Acta Ophthalmol 2019 Feb 27. Epub 2019 Feb 27.

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Purpose: Selective laser trabeculoplasty (SLT) is one of the many treatment options for lowering intraocular pressure (IOP) in patients with glaucoma. This study aimed to evaluate the effect of SLT.

Methods: Data were collected from medical records of 289 patients who underwent SLT treatment (180° of trabecular meshwork) during 2014 and 2015 at the Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Sweden. Read More

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http://dx.doi.org/10.1111/aos.14067DOI Listing
February 2019
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Postural effects on spontaneous retinal venous pulsations in healthy individuals.

Acta Ophthalmol 2019 Feb 25. Epub 2019 Feb 25.

Vision Science group, Graduate School of Health (Orthoptics Discipline), University of Technology Sydney, Ultimo, NSW, Australia.

Purpose: To assess amplitudes of spontaneous retinal venous pulsations (SVP) in three various postures (sitting, supine and lateral decubitus) in healthy individuals.

Methods: Thirty participants (28 ± 8 years, 25 females) were included in the study. Intraocular pressure (IOP), blood pressure (BP) and SVP's were measured at three different postures using a calibrated Tono-Pen applanation tonometer, a digital sphygmomanometer, and a custom-built handheld video ophthalmoscope, respectively. Read More

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http://dx.doi.org/10.1111/aos.14068DOI Listing
February 2019
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2.844 Impact Factor

Aqueous semaphorin 3A level correlates with retinal macular oedema and ganglion cell degeneration in patients with retinal vein occlusion.

Acta Ophthalmol 2019 May 25;97(3):273-278. Epub 2019 Feb 25.

Department of Ophthalmology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Purpose: To investigate the semophorin 3A (SEMA3A) level in aqueous humor of patients with retinal vein occlusion (RVO) and explore the correlation of SEMA3A with macular oedema and ganglion cell degeneration in RVO.

Methods: This comparative study prospectively included 41 consecutive patients (41 eyes) with RVO who had intravitreal anti-VEGF injections from March 2014 to March 2015 for cystoid macular oedema (CME) or neovascular glaucoma (NVG). The patients were divided into three groups according to the fluorescein angiograghy (FFA): central retinal vein occlusion (CRVO) group (n = 15), branch retinal vein occlusion (BRVO) group (n = 15) and NVG group (secondary to CRVO, n = 11). Read More

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http://dx.doi.org/10.1111/aos.14079DOI Listing
May 2019
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Prospective evaluation of clinical outcomes between pre-cut corneal grafts prepared using a manual or automated technique: with one-year follow-up.

Acta Ophthalmol 2019 Feb 25. Epub 2019 Feb 25.

Utrecht Cornea Research Group, Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands.

Purpose: Posterior lamellar corneal surgery is considered the standard of care for irreversible endothelial cell dysfunction. Pre-cut grafts can be prepared either manually (Descemet stripping endothelial keratoplasty; DSEK) or mechanically (Descemet stripping automated endothelial keratoplasty; DSAEK). We performed a head-to-head clinical comparison between DSEK and DSAEK grafts. Read More

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http://dx.doi.org/10.1111/aos.14074DOI Listing
February 2019
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Does eye examination order for standard automated perimetry matter?

Acta Ophthalmol 2019 Feb 22. Epub 2019 Feb 22.

Division of Optometry and Visual Science, School of Health Science, City, University of London, London, UK.

Purpose: In spite of faster examination procedures, visual field (VF) results are potentially influenced by fatigue. We use large-scale VF data collected from clinics to test the hypothesis that perimetric fatigue effects are greater in the eye examined second.

Methods: Series of six Humphrey Swedish Interactive Testing Algorithm (SITA) VFs from 6901 patients were retrospectively extracted from a VF database from four different glaucoma clinics. Read More

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http://dx.doi.org/10.1111/aos.14069DOI Listing
February 2019
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Visual field requirements for driving in Europe: the risk of inaccurate interpretation of visual field findings when using the binocular Esterman programme.

Acta Ophthalmol 2019 Feb 22. Epub 2019 Feb 22.

Working Group on Driving and Vision Standards, Norwegian Ophthalmological Society, Oslo, Norway.

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http://dx.doi.org/10.1111/aos.14071DOI Listing
February 2019
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