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    9519 results match your criteria Acta Obstetricia et Gynecologica Scandinavica[Journal]

    1 OF 191

    Postnatal depression in a community-based study of women with polycystic ovary syndrome.
    Acta Obstet Gynecol Scand 2018 Feb 20. Epub 2018 Feb 20.
    School of Public Health, The University of Adelaide, Adelaide.
    Introduction: Women with polycystic ovary syndrome (PCOS) are susceptible to depression and anxiety, so may also be at risk for postnatal depression (PND). This study investigates whether women with PCOS have an elevated risk of PND.

    Material And Methods: Cross-sectional data for parous women (n=566) were available from a birth cohort. Read More

    Cross-sectional studies - what are they good for?
    Acta Obstet Gynecol Scand 2018 Feb 17. Epub 2018 Feb 17.
    Department of Obstetrics and Gynecology, Herlev University Hospital, Herlev.
    Cross-sectional studies serve many purposes, and the cross-sectional design is the most relevant design when assessing the prevalence of disease, attitudes and knowledge among patients and health personnel, in validation studies comparing e.g. different measurement instruments, and in reliability studies. Read More

    Information bias in epidemiological studies with a special focus on obstetrics and gynecology.
    Acta Obstet Gynecol Scand 2018 Feb 17. Epub 2018 Feb 17.
    Department of Obstetrics and Gynecology, Herlev University Hospital, Herlev.
    Information bias occurs when any information used in a study is either measured or recorded inaccurately. This paper describes some of the most common types of information bias, using examples from obstetrics and gynecology, and describes how information bias may affect results of observational studies. Non-differential misclassification occurs when the degree of misclassification of exposure status among those with and those without the disease is the same, and in cohort studies, this type of bias is most likely and will bias estimates toward no association when exposure is dichotomized. Read More

    Is sonographically measured cervical length at 37 weeks' gestation associated with intrapartum cesarean section? A prospective cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 16. Epub 2018 Feb 16.
    RPA Women and Babies, Royal Prince Alfred Hospital, Sydney.
    Introduction: Cesarean section rates continue to increase globally. Prediction of intrapartum cesarean section could lead to preventative measures. Our aim was to assess the association between sonographically measured cervical length at 37 weeks' gestation and cesarean section among women planning a vaginal birth. Read More

    Antepartum risk factors for moderate to severe neonatal hypoxic ischemic encephalopathy: a Swedish national cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 16. Epub 2018 Feb 16.
    Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
    Introduction: Our aim was to identify antepartum risk factors for neonatal hypoxic ischemic encephalopathy (HIE), with a focus on maternal body mass index and height.

    Material And Methods: National population-based cohort study of 692 428 live-born infants ≥ 36 gestational weeks in Sweden, 2009-2015. Data from the Swedish Medical Birth Register and the Swedish Neonatal Quality Register were linked. Read More

    Alcohol binge drinking in early pregnancy and the effect on fetal growth: A cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 12. Epub 2018 Feb 12.
    Department of Obstetrics and Gynecology, Herlev Hospital, Herlev.
    Introduction: Alcohol binge drinking is common in early pregnancy and is a well-established risk factor for subsequent child health. Yet very few studies have investigated the effect on fetal growth. Furthermore it has also been speculated whether the timing of binge drinking is a determining factor for neonatal growth. Read More

    Adverse childhood experiences and depressive symptomatology among pregnant women.
    Acta Obstet Gynecol Scand 2018 Feb 12. Epub 2018 Feb 12.
    Family Medicine and Preventive Medicine unit, Uppsala Department of Public Health and Caring Sciences, University of Uppsala, Uppsala.
    Introduction: Adverse childhood experiences (ACE) result in somatic and mental health disturbances. Its influence on antenatal depression is scarcely studied. This study examined the association between experience of ACE and antenatal depressive symptomatology. Read More

    Medical treatment in the management of deep endometriosis infiltrating the proximal rectum and sigmoid colon: a comprehensive literature review.
    Acta Obstet Gynecol Scand 2018 Feb 12. Epub 2018 Feb 12.
    IRCCS Ca 'Granda Foundation - Maggiore Policlinico Hospital, Milan, Italy.
    A comprehensive literature review was performed to evaluate the effect of various hormonal therapies, in terms of variations of intestinal and pain complaints and of patient satisfaction with treatment, in women with symptomatic, non-severely sub-occlusive endometriosis infiltrating the proximal rectum and sigmoid colon. A MEDLINE search through PubMed from 2000 to 2018 was conducted to identify all original English language articles published on medical treatment for colorectal endometriosis. Additional reports were identified by systematically reviewing reference lists and using the "similar articles" function in PubMed. Read More

    Comparison of self-reported and directly measured weight and height among women of reproductive age: a systematic review and meta-analysis.
    Acta Obstet Gynecol Scand 2018 Feb 11. Epub 2018 Feb 11.
    Department of Mother and Child Health Research, Institute for Clinical Effectiveness and Health Policy (IECS-CONICET), Buenos Aires, Argentina.
    Introduction: The use of self-report as a strategy for collecting data of women's weight and height is broadly spread both in clinical practice and epidemiological studies. This study aimed to compare self-reported and directly measured weight and height among women of reproductive age.

    Material And Methods: In July 2015 we searched MEDLINE, EMBASE, COCHRANE, CINHAL, LILACS and grey literature. Read More

    HPV-testing vs. HPV-cytology co-testing to predict the outcome after conization.
    Acta Obstet Gynecol Scand 2018 Feb 11. Epub 2018 Feb 11.
    Department of Pathology, Southern Jutland Hospital, Sønderborg, Denmark.
    Introduction: The purpose of this study was to determine the feasibility of human papillomavirus (HPV) testing alone as prognostic tool to predict recurrent disease within a three years follow-up period after treatment for cervical intraepithelial neoplasia (CIN)2+.

    Material And Methods: Retrospectively 128 women, with histologically verified CIN2+, who had a conization performed at Southern Jutland Hospital in Denmark between January 1st 2013 and December 31st 2013 were included. Histology, cytology and HPV test results were obtained for a 3 years follow-up period. Read More

    HELLP syndrome, risk factors in first and second pregnancy: a population-based cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 11. Epub 2018 Feb 11.
    Department of Clinical Science, University of Bergen, Bergen, Norway.
    Introduction: HELLP syndrome may have specific risk factors and risk factors varying from first to second pregnancy. The aims of the study were to estimate the risk of HELLP syndrome by potential risk factors in first and second pregnancy, respectively.

    Material And Methods: A population based cohort study including all women in Norway having their first baby (≥22 gestational weeks) during 1999 to 2014, registered in the Medical Birth Registry (n=418 897). Read More

    Perinatal outcome of monochorionic and dichorionic twins after spontaneous and assisted conception: a retrospective cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 11. Epub 2018 Feb 11.
    Department of Obstetrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht.
    Introductio: The aim of this study was to compare pregnancy outcomes in twin pregnancies after ACand spontaneous conception, according to chorionicity.

    Material And Methods: Retrospective cohort study of 1305 twin pregnancies between 1995 and 2015. All spontaneous (n=731) and assisted conception conceived twin pregnancies (n=574) with antenatal care and delivery in University Medical Center Utrecht, The Netherlands, a tertiary obstetric care center were studied according to chorionicity. Read More

    How to investigate and adjust for selection bias in cohort studies.
    Acta Obstet Gynecol Scand 2018 Feb 7. Epub 2018 Feb 7.
    Department of Epidemiology, Fielding School of Public Health, University of California (UCLA), Los Angeles, California, USA.
    Longitudinal cohort studies can provide important evidence about preventable causes of disease, but the success relies heavily on the commitment of their participants, both at recruitment and during follow-up. Initial participation rates have decreased in recent decades as have willingness to participate in subsequent follow-ups. It is important to examine how such selection affects the validity of the results. Read More

    Associations between parity and maternal BMI in a population-based cohort study.
    Acta Obstet Gynecol Scand 2018 Feb 7. Epub 2018 Feb 7.
    Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus.
    Introduction: We aimed to investigate the change in prevalence of overweight and obesity in pregnant Danish women from 2004 to 2012 and investigate whether increasing parity was associated with a change in BMI prevalence.

    Material And Methods: We obtained a population-based cohort from the Danish Medical Birth registry consisting of all Danish women giving birth from 2004-2012 (n=572 321). This registry contains information on 99. Read More

    Screening for fetal and neonatal alloimmune thrombocytopenia - lessons learned from a Norwegian screening program.
    Acta Obstet Gynecol Scand 2018 Feb 7. Epub 2018 Feb 7.
    Immunology Research Group, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.
    An important issue on human platelet antigen (HPA)-1a screening has recently been addressed in Acta Obstetrica et Gynecologica Scandinavia. Winkelhorst et al. reported that the vast majority of women in the general pregnant population were positive about screening (1). Read More

    Can pelvic floor trauma be predicted antenatally?
    Acta Obstet Gynecol Scand 2018 Feb 2. Epub 2018 Feb 2.
    Sydney Medical School Nepean, University of Sydney, Nepean Hospital, Penrith, NSW, Australia.
    Introduction: Levator trauma is a risk factor for development of pelvic organ prolapse. We aimed to identify antenatal predictors for significant damage to the levator ani muscle during first vaginal delivery.

    Materials And Methods: A retrospective observational study utilising data from two studies with identical inclusion criteria and assessment protocols between 2005 and 2014. Read More

    An overview of cervical cancer epidemiology and prevention in Scandinavia.
    Acta Obstet Gynecol Scand 2018 Feb 1. Epub 2018 Feb 1.
    Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway.
    New technologies such as human papillomavirus (HPV) testing and vaccination necessitates comprehensive policy analyses to optimize cervical cancer prevention. To inform future Scandinavian-specific policy analyses, we aimed to provide an overview of cervical cancer epidemiology and existing prevention efforts in Denmark, Norway and Sweden. We compiled and summarized data on current prevention strategies, population demography, and epidemiology (e. Read More

    Is TWEAK a valid screening questionnaire to identify alcohol risk drinkers among pregnant women in Denmark?
    Acta Obstet Gynecol Scand 2018 Jan 30. Epub 2018 Jan 30.
    Department of Obstetrics & Gynecology, Herlev University Hospital, Herlev, Denmark.
    Introduction: Identification of pregnant alcohol risk drinkers is crucial to prevent adverse birth outcomes. The TWEAK screening instrument has shown promising results for identifying risk drinkers. However, as the effectiveness of the screening questionnaire has only been investigated among American women with mainly low socioeconomic status, we aimed to investigate the ability of TWEAK to identify alcohol risk drinkers among pregnant Danish women. Read More

    Brainstem auditory abnormality in extremely premature babies and the impact of neonatal bronchopulmonary dysplasia.
    Acta Obstet Gynecol Scand 2018 Jan 30. Epub 2018 Jan 30.
    Division of Neonatology, Children's Hospital, Fudan University, Shanghai, China.
    Introduction: Extremely premature babies, particularly those who have neonatal bronchopulmonary dysplasia (BPD), are at risk of brain damage and neurodevelopmental impairment. This study aimed to examine functional status of the brainstem auditory pathway in extremely premature babies and assess the impact of BPD on the function.

    Material And Methods: Brainstem auditory evoked response was studied at term in babies born at 27 or less weeks of gestation with or without neonatal BPD. Read More

    Non-invasive diagnostic tools for pelvic congestion syndrome: a systematic review.
    Acta Obstet Gynecol Scand 2018 Jan 30. Epub 2018 Jan 30.
    Department of Obstetrics and Gynecology, Radboud University Medical Centre, Nijmegen, the Netherlands.
    Introduction: In the work-up of patients with suspected pelvic congestion syndrome, venography is currently the gold standard. Yet if non-invasive diagnostic tools are found to be accurate, invasive venography might no longer be indicated as necessary.

    Material And Methods: A literature search in Pubmed and EMBASE was performed from inception until May 6th 2017. Read More

    A simplified guide to randomized controlled trials.
    Acta Obstet Gynecol Scand 2018 Jan 27. Epub 2018 Jan 27.
    Department of Clinical Science, Intervention and Technology, Karolinska Institute and Center for Fetal Medicine, Karolinska University Hospital, Stockholm, Sweden.
    A randomized controlled trial (RCT) is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random allocation of interventions to comparison groups. The RCT is the most rigorous and robust research method of determining whether a cause-effect relationship exists between an intervention and an outcome. High quality evidence can be generated by performing an RCT when evaluating the effectiveness and safety of an intervention. Read More

    Coffee, tea and caffeine consumption and risk of primary infertility in women: a Danish cohort study.
    Acta Obstet Gynecol Scand 2018 Jan 24. Epub 2018 Jan 24.
    Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
    Introduction: The aim of this study was to investigate whether consumption of coffee, tea and caffeine affects the risk of primary infertility in women.

    Material And Methods: We selected nulliparous Danish women aged 20-29 years from a prospective cohort and retrieved information on coffee and tea consumption from a questionnaire and an interview at enrollment. We assessed the women's fertility by linkage to the Danish Infertility Cohort and retrieved information on children and vital status from the Civil Registration System. Read More

    Antenatal corticosteroids: a retrospective cohort study on timing, indications and neonatal outcome.
    Acta Obstet Gynecol Scand 2018 Jan 23. Epub 2018 Jan 23.
    Department of Clinical Sciences, Lund University, Lund, Sweden.
    Introduction: An antenatal corticosteroid (ACS) delivery interval of 24 h to seven days is commonly referred to as optimal timing. We aimed to investigate whether the ACS delivery interval was associated with the obstetric indication for treatment and with neonatal complications.

    Material And Methods: The study was a retrospective chart review of clinical data from preterm neonates delivered at the Skåne University Hospital, Lund University, Sweden, from 1 January 2013 to 31 December 2016. Read More

    The effect of ethnicity on the performance of protein-creatinine ratio in the prediction of significant proteinuria in pregnancies at risk of or with established hypertension: an implementation audit and cost implications.
    Acta Obstet Gynecol Scand 2018 Jan 21. Epub 2018 Jan 21.
    Antenatal Hypertension Clinic, Division of Women's Health, King's College Hospital, London, UK.
    Introduction: The replacement of 24-h urine collection by protein-creatinine ratio (PCR) for the diagnosis of preeclampsia has been recently recommended. However, the literature is conflicting and there are concerns about the impact of demographic characteristics on the performance of PCR.

    Material And Methods: This was an implementation audit of the introduction of PCR in a London Tertiary obstetric unit. Read More

    Laeverin protein expression in normal and preeclamptic placentas using tissue microarray analysis.
    Acta Obstet Gynecol Scand 2018 Jan 21. Epub 2018 Jan 21.
    Women's Health and Perinatology Research Group, Department of Clinical Medicine, Faculty of Health Sciences UiT - The Arctic University of Norway, Tromsø, Norway.
    Introduction: Laeverin is a placenta-specific protein that is normally expressed in the plasma membrane of human trophoblasts. In previous studies, we showed higher expression levels of laeverin gene in preeclamptic compared with normal placentas and found that laeverin protein was ectopically expressed in the cytoplasm of the preeclamptic placentas. Our objective was to investigate laeverin protein expression in normal and preeclamptic placentas combining immunohistochemistry and immunofluorescence. Read More

    Association of microRNA-200c expression levels with clinicopathological factors and prognosis in endometrioid endometrial cancer.
    Acta Obstet Gynecol Scand 2018 Jan 21. Epub 2018 Jan 21.
    Department of Surgical and Endoscopic Gynecology, Medical University in Lodz, Lodz, Poland.
    Introduction: MicroRNAs (miRNAs) are regulators of gene expression, which play an important role in many critical cellular processes including apoptosis, proliferation and cell differentiation. Aberrant miRNA expression has been reported in a variety of human malignancies. Therefore, miRNAs may be potentially used as cancer biomarkers. Read More

    Accuracy of fetal fibronectin for assessing preterm birth risk in asymptomatic pregnant women: a systematic review and meta-analysis.
    Acta Obstet Gynecol Scand 2018 Jan 21. Epub 2018 Jan 21.
    Barts Health NHS Trust, The Royal London Hospital, London, UK.
    Introduction: Fetal fibronectin (fFN) is a validated test for assessing risk of preterm birth for women presenting with symptoms. Our aim was to evaluate the accuracy of fFN to detect the risk of preterm birth in asymptomatic women.

    Material And Methods: Searches were conducted to identify studies where fFN was performed in asymptomatic women beyond 22 weeks' gestation. Read More

    Systematic misclassification of gestational age by ultrasound biometry: implications for clinical practice and research methodology in the Nordic countries.
    Acta Obstet Gynecol Scand 2018 Jan 20. Epub 2018 Jan 20.
    Department of Obstetrics and Gynecology, Herlev University Hospital, University of Copenhagen, Herlev, Denmark.
    Historically, pregnancy dating has been based on self-reported information on the first day of the last menstrual period. In the 1970s, ultrasound biometry was introduced as an alternative for pregnancy dating and is now the leading method in Nordic countries. The use of ultrasound led to a reduction of post-term births and fewer inductions, and is considered more precise than last menstrual period-based methods for pregnancy dating. Read More

    Pelvic floor muscle function and quality of life in postmenopausal women with and without pelvic floor dysfunction.
    Acta Obstet Gynecol Scand 2018 Jan 20. Epub 2018 Jan 20.
    Department of Surgery, Maternidade Escola Assis Chateaubriand and Department of Maternal-Child Health, Federal University of Ceará, Fortaleza, CE, Brazil.
    Introduction: This study aims to compare pelvic floor muscle (PFM) function in postmenopausal women with and without pelvic floor dysfunction (PFD) and the relationship between PFM function and quality of life.

    Material And Methods: A case-control study with 216 postmenopausal women with (n = 126) and without (n = 90) PFD. PFM function was assessed by digital vaginal palpation using the PERFECT scale. Read More

    Low semen quality and experiences of masculinity and family building.
    Acta Obstet Gynecol Scand 2018 Jan 19. Epub 2018 Jan 19.
    Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
    Introduction: Infertility is a concern for men and women.There is limited knowledge on how male factor infertility affects the couple in fertility treatment. The aim of this study was to explore how severe male factor infertility affects men's sense of masculinity, the couple's relationship and intentions about family formation. Read More

    Positive view and increased likely uptake of follow-up testing with analysis of cell-free fetal DNA as alternative to invasive testing among Danish pregnant women.
    Acta Obstet Gynecol Scand 2018 Jan 19. Epub 2018 Jan 19.
    Center of Fetal Medicine, Department of Obstetrics, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
    Introduction: To investigate the attitude (view, likely uptake and preferred strategy) towards cell-free fetal DNA (cfDNA) testing among pregnant women before a first-trimester risk assessment for trisomy 21 (unselected women) and after obtaining a high risk.

    Material And Methods: Unselected and high-risk women attending first-trimester screening (Rigshospitalet, Copenhagen University Hospital) were invited to fill out the questionnaire Antenatal testing for Down syndrome as an online survey.

    Results: The survey included 203 unselected and 50 high-risk women (response rates of 74. Read More

    Preeclampsia and scleroderma: a prospective nationwide analysis.
    Acta Obstet Gynecol Scand 2018 Jan 18. Epub 2018 Jan 18.
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
    Introduction: In a preliminary case-control study, women with scleroderma more frequently reported having had hypertensive complications during pregnancy compared with healthy women.

    Material And Methods: To prospectively investigate this possible association, we conducted a nation-wide cohort analysis of a major hypertensive complication during pregnancy, namely preeclampsia, and later scleroderma. Analyses were based on Danish register-based birth and hospital contact data on preeclampsia and scleroderma. Read More

    An overview of confounding. Part 1: the concept and how to address it.
    Acta Obstet Gynecol Scand 2018 Jan 17. Epub 2018 Jan 17.
    Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
    Confounding is an important source of bias, but it is often misunderstood. We consider how confounding occurs and how to address confounding using examples. Study results are confounded when the effect of the exposure on the outcome, mixes with the effects of other risk and protective factors for the outcome. Read More

    An overview of confounding. Part 2: how to identify it and special situations.
    Acta Obstet Gynecol Scand 2018 Jan 17. Epub 2018 Jan 17.
    Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
    Confounding biases study results when the effect of the exposure on the outcome mixes with the effects of other risk and protective factors for the outcome that are present differentially by exposure status. However, not all differences between the exposed and unexposed group cause confounding. Thus, sources of confounding must be identified before they can be addressed. Read More

    The influence of delayed cord clamping and cord milking on inflammatory cytokines in umbilical vein and neonatal circulation.
    Acta Obstet Gynecol Scand 2018 Jan 16. Epub 2018 Jan 16.
    3rd Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
    Introduction: The purpose of the present study was to compare the levels of tumor necrosis factor α (TNF-α), and interleukins (IL) 1, 6, 8 and 10 in the umbilical cord and neonatal circulation among neonates with early and late cord clamping.

    Material And Methods: A consecutive series of 76 cases of uncomplicated pregnancy and an uneventful parturition was evaluated. In 40 cases, delayed cord clamping was used and in the remaining 36, early cord clamping was practiced. Read More

    Preventing Posttraumatic Stress Disorder following childbirth and traumatic birth experiences: A systematic review.
    Acta Obstet Gynecol Scand 2018 Jan 16. Epub 2018 Jan 16.
    University Medical Center Utrecht, Utrecht, the Netherlands.
    Introduction: Between 9 and 44% of women experience giving birth as traumatic, and 3% of women develop a posttraumatic stress disorder following childbirth. Knowledge on risk factors is abundant, but studies on treatment are limited. This study aimed to present an overview of means to prevent traumatic birth experiences and childbirth-related posttraumatic stress disorder. Read More

    Intraoperative adverse events associated with extremely preterm cesarean deliveries.
    Acta Obstet Gynecol Scand 2018 Jan 16. Epub 2018 Jan 16.
    Port-Royal Maternity Unit, Cochin Hospital, Paris-Descartes University, DHU Risk and Pregnancy, Assistance Publique-Hôpitaux de Paris, Paris, France.
    Introduction: At the same time as survival is increasing among premature babies born before 26 weeks of gestation, the rates of cesarean deliveries before 26 weeks is also rising. Our purpose was to compare the frequency of intraoperative adverse events during cesarean deliveries in two gestational age groups: 24-25 weeks and 26-27 weeks.

    Material And Methods: This single-center retrospective cohort study included all women with cesarean deliveries performed before 28weeks from 2007 through 2015. Read More

    Postpartum computed tomography angiography of the fetoplacental macrovasculature in normal pregnancies and in those complicated by fetal growth restriction.
    Acta Obstet Gynecol Scand 2018 Mar;97(3):322-329
    Department of Obstetrics and Gynecology, Aalborg University Hospital, Aalborg, Denmark.
    Introduction: Current knowledge of the fetoplacental vasculature in fetal growth restriction (FGR) due to placental dysfunction focuses on the microvasculature rather than the macrovasculature. The aim of this study was to investigate the feasibility of computed tomography angiography to analyze the fetoplacental macrovasculature in normal and FGR pregnancies.

    Material And Methods: We included 29 placentas (22-42 weeks of gestation) from normal birthweight pregnancies and eight placentas (26-37 weeks of gestation) from FGR pregnancies (birthweight < -15% and abnormal umbilical Doppler flow). Read More

    Antenatal vaccination against Group B streptococcus: attitudes of pregnant women and healthcare professionals in the UK towards participation in clinical trials and routine implementation.
    Acta Obstet Gynecol Scand 2018 Mar 19;97(3):330-340. Epub 2018 Jan 19.
    Oxford Vaccine Group, Department of Pediatrics, University of Oxford and the NIHR Oxford Biomedical Research Center, Oxford, UK.
    Introduction: Maternal vaccination is increasingly part of antenatal care in the UK and worldwide. Trials of Group B streptococcus vaccines are ongoing. This study investigated the attitudes of pregnant women and healthcare professionals towards antenatal vaccination, both in routine care and a clinical trial setting. Read More

    Fetal aneuploidy diagnosed at celocentesis for early prenatal diagnosis of congenital hemoglobinopathies.
    Acta Obstet Gynecol Scand 2018 Mar 24;97(3):312-321. Epub 2018 Jan 24.
    Unit of Hematology for Rare Diseases of the Blood and Blood-forming Organs, Laboratory for Molecular Diagnosis of Rare Diseases, Hospital Villa Sofia Cervello, Palermo, Italy.
    Introduction: Currently, prenatal diagnosis of genetic disorders requires chorionic villus sampling or amniocentesis carried out after 11 and 16 weeks of gestation, respectively. Celocentesis is a procedure for prenatal diagnosis that could be used from as early as 7 weeks. The present investigation evaluated the feasibility of performing diagnosis for monogenic diseases using celomic fluid containing cells of fetal origin. Read More

    Waterbirth in Sweden - a comparative study.
    Acta Obstet Gynecol Scand 2018 Mar 17;97(3):341-348. Epub 2018 Jan 17.
    Sophiahemmet University, Stockholm, Sweden.
    Introduction: The literature describes advantages for mothers giving birth in water, but waterbirth is controversial in Sweden and has not been offered at hospitals until recently. This study aimed to describe and compare the characteristics and outcome of waterbirths with those of spontaneous vaginal births at the same clinics.

    Material And Methods: A retrospective cohort study was conducted on all waterbirths at two maternity units in Sweden from March 2014 to November 2015 (n = 306), and a consecutively selected comparison group of 306 women having conventional spontaneous vaginal births. Read More

    Cost-effectiveness of curettage vs. expectant management in women with an incomplete evacuation after misoprostol treatment for first-trimester miscarriage: a randomized controlled trial and cohort study.
    Acta Obstet Gynecol Scand 2018 Mar 19;97(3):294-300. Epub 2018 Jan 19.
    Department of Health Sciences, Faculty of Earth and Life Sciences, Free University Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
    Introduction: Curettage is more effective than expectant management in women with suspected incomplete evacuation after misoprostol treatment for first-trimester miscarriage. The cost-effectiveness of curettage vs. expectant management in this group is unknown. Read More

    Low levels of anti-secretory factor in placenta are associated with preterm birth and inflammation.
    Acta Obstet Gynecol Scand 2018 Mar 8;97(3):349-356. Epub 2018 Jan 8.
    Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
    Introduction: Anti-secretory factor is a protein that regulates secretory and inflammatory processes and preterm birth is associated with inflammation. Therefore, our hypothesis was that anti-secretory factor might play a role in immune reactivity and homeostasis during pregnancy.

    Material And Methods: Following spontaneous onset of labor and preterm or term delivery, placenta biopsies were collected. Read More

    A prospective investigation of perceived stress, infertility-related stress, and cortisol levels in women undergoing in vitro fertilization: influence on embryo quality and clinical pregnancy rate.
    Acta Obstet Gynecol Scand 2018 Mar 10;97(3):258-268. Epub 2018 Jan 10.
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
    Introduction: Women undergoing fertility treatment experience high levels of stress. However, it remains uncertain if and how stress influences in vitro fertilization (IVF) cycle outcome. This study aimed to investigate whether self-reported perceived and infertility-related stress and cortisol levels were associated with IVF cycle outcomes. Read More

    Treatment-related psychological stress in different in vitro fertilization therapies with and without gonadotropin stimulation.
    Acta Obstet Gynecol Scand 2018 Mar 8;97(3):269-276. Epub 2018 Jan 8.
    Divison of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Berne, Switzerland.
    Introduction: Infertility treatments such as in vitro fertilization (IVF) impose substantial distress. However, the specific role of individual contributory factors remains unclear. We therefore compared treatment-related psychological stress in IVF treatments with (cIVF) and without (NC-IVF) gonadotropin stimulation, as cIVF includes potentially stressful factors such as ovarian stimulation, anesthesia, embryo selection and cryopreservation, whereas NC-IVF does not. Read More

    Outcome of sonography-based minimally invasive surgery for deep infiltrating endometriosis of the ureter and urinary bladder - a retrospective cohort study.
    Acta Obstet Gynecol Scand 2018 Mar 29;97(3):277-284. Epub 2017 Dec 29.
    Department of Urology, Hospital St. John of God, Vienna, Austria.
    Introduction: The aim of this study was to evaluate the accuracy of transvaginal sonography for preoperative detection of bladder endometriosis and surgical outcomes regarding fertility and pain symptoms of women with urinary tract endometriosis.

    Material And Methods: Retrospective cohort study of consecutive patients with urinary tract endometriosis undergoing laparoscopic partial cystectomy and/or ureterolysis/decompression, ureteric resection and end-to-end anastomosis or ureteroneocystostomy for ureteral stenosis and hydronephrosis.

    Results: Of 207 patients with deep infiltrating endometriosis, 50 exhibited urinary tract endometriosis, comprising 30 patients with bladder endometriosis and 23 women with solitary or additional hydronephrosis. Read More

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