9,795 results match your criteria Acta Obstetricia et Gynecologica Scandinavica[Journal]


Twenty years of development in fertility preservation of women and girls and the challenges that remain.

Acta Obstet Gynecol Scand 2019 May;98(5):543-544

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13615
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http://dx.doi.org/10.1111/aogs.13615DOI Listing
May 2019
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Shock index thresholds to predict adverse outcomes in maternal hemorrhage and sepsis: a prospective cohort study.

Acta Obstet Gynecol Scand 2019 Apr 18. Epub 2019 Apr 18.

Department of Women and Children's Health, King's College London, London, UK.

Introduction: Shock Index (SI) is a predictor of hemodynamic compromise in obstetric patients. The Shock Index threshold for action is not well understood. We aimed to evaluate Shock Index thresholds as predictors of outcomes in obstetric patients. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13626
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http://dx.doi.org/10.1111/aogs.13626DOI Listing
April 2019
1 Read

Contraception after pregnancy.

Acta Obstet Gynecol Scand 2019 Apr 18. Epub 2019 Apr 18.

University of Milan, Milano, Lombardia, Italy.

Whatever the outcome, pregnancy provides the opportunity to offer effective contraception to couples motivated to avoid another pregnancy. This narrative review summarises the evidence for health providers, drawing attention to current guidelines, on which contraceptive methods can be used, and when they should be started after pregnancy, whatever its outcome. Fertility returns within one month of the end of pregnancy unless breastfeeding occurs. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13627
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http://dx.doi.org/10.1111/aogs.13627DOI Listing
April 2019
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The effect of myo-inositol/di-chiro-inositol on markers of ovarian reserve in women with PCOS undergoing IVF/ICSI: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Apr 16. Epub 2019 Apr 16.

Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

Introductio: High levels of anti-Mullerian hormone and a high antral follicle count in women with polycystic ovary syndrome, reflecting increased ovarian antral follicles, predisposes them to have a high number of retrieved oocytes at in-vitro fertilisation (IVF)/ intra-cytoplasmic sperm injection (ICSI) and an increased risk of ovarian hyperstimulation syndrome. Inositols, which act as insulin sensitizers have the potential to alter folliculogenesis and the functional ovarian reserve with subsequent benefits to reproductive outcomes following IVF/ICSI treatment. Published literature is however unable to provide definitive evidence of its efficacy. Read More

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http://dx.doi.org/10.1111/aogs.13625DOI Listing

Niche definition and guidance for detailed niche evaluation.

Acta Obstet Gynecol Scand 2019 Apr 15. Epub 2019 Apr 15.

Department of Gynecology and Obstetrics, Research institute "Reproduction and Development", Amsterdam UMC, location VU medical center, Amsterdam, The Netherlands.

With interest we read the correspondence of Bamberg et al. and Scioscia et al. about the randomized controlled trial of the first authors concerning the uterine niche after caesarean section (CS). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13623
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http://dx.doi.org/10.1111/aogs.13623DOI Listing
April 2019
2 Reads

Health-related quality of life during pregnancy: a repeated measures study of changes from the first trimester to birth.

Acta Obstet Gynecol Scand 2019 Apr 15. Epub 2019 Apr 15.

Department of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, Toulouse, France.

Introduction: The objective was to evaluate the quality of life of pregnant women with a full-term birth from the first trimester to the 9th month using the EQ5D-3L questionnaire, comparing physiological, simple pathological or complex pathological pregnancies.

Material And Methods: A prospective cohort of 500 pregnant women over the age of 18 was monitored between 2015 and 2017 at the Toulouse University Hospital (France). The data were collected monthly with an online report. Read More

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http://dx.doi.org/10.1111/aogs.13624DOI Listing
April 2019
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Ventriculo-amniotic shunting for severe fetal ventriculomegaly.

Acta Obstet Gynecol Scand 2019 Apr 12. Epub 2019 Apr 12.

Department of Gynecology, Fertility and Fetal Therapy, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.

Introduction: Severe fetal cerebral ventriculomegaly, observed in about 1 in 1,000 newborns is associated with a high risk of perinatal death and neurodevelopmental delay in survivors. The objective of this study was to evaluate the efficiency of ventriculo-amniotic shunting for drainage of severe fetal cerebral ventriculomegaly and the neurodevelopment of survivors at the age of 2 years.

Material And Methods: This was a retrospective study of 44 fetuses with severe bilateral ventriculomegaly treated with ventriculo-amniotic shunting in a tertiary fetal therapy center between 2010 and 2015. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13622
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http://dx.doi.org/10.1111/aogs.13622DOI Listing
April 2019
3 Reads

Elective egg freezing - better younger but effective enough?

Acta Obstet Gynecol Scand 2019 Apr 10. Epub 2019 Apr 10.

Wales Fertility Institute, Cardiff University, Cardiff, UK.

We read with interest the correspondence commenting on our review on fertility preservation without medical indications by Levin and Rottenstreich. The purpose of our manuscript was to summarise the highlights of social freezing regarding chances of success, safety, costs and socio/ethical issues. The authors claimed limits of studies that deal with the issue on optimal timing of oocyte cryopreservation, concluding that eggs freezing should be performed as early as possible. Read More

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http://dx.doi.org/10.1111/aogs.13618DOI Listing

Conservative treatment of rectosigmoid endometriosis: a prospective study.

Acta Obstet Gynecol Scand 2019 Apr 10. Epub 2019 Apr 10.

Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.

Introduction: Deep infiltrating endometriosis is a common cause of pelvic pain. However, some patients have limited problems that may be controlled by medical treatment, thus avoiding potentially severe complications to major surgery. This approach requires detailed knowledge on the quality of life and clinical symptoms over time. Read More

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http://dx.doi.org/10.1111/aogs.13619DOI Listing
April 2019
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The development of an extended normothermic ex vivo reperfusion model of the sheep uterus to evaluate organ quality after cold ischemia in relation to uterus transplantation.

Acta Obstet Gynecol Scand 2019 Apr 1. Epub 2019 Apr 1.

Laboratory for Transplantation and Regenerative Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Introduction: Uterus transplantation has recently proved that infertility in women with uterine factor infertility can be cured. It is still an experimental procedure with numerous critical details remaining to be established, including tolerance to warm and cold ischemic insults. In preparation for human uterus transplantation trials, most teams use the sheep as a model system for research and team training, since the vasculature and the uterus is of similar size as in the human. Read More

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http://dx.doi.org/10.1111/aogs.13617DOI Listing

Ovarian tissue cryopreservation for fertility preservation in 418 girls and adolescents up to 15 years of age facing highly gonadotoxic treatment. Twenty years of experience at a single center.

Acta Obstet Gynecol Scand 2019 May 14;98(5):630-637. Epub 2019 Apr 14.

Department of Pediatric Hemato-Immunology, Hospital Robert Debré, Paris, France.

Introduction: The preservation of fertility is an integral part of care of children requiring gonadotoxic treatments for cancer or non-malignant diseases. In France, the cryopreservation of ovarian tissue has been considered and has been offered as a clinical treatment since its inception. The aim of this study is to review 20 years of activity in fertility preservation by ovarian tissue cryopreservation (OTC) for children and the feasibility of oocyte isolation and cryopreservation from the ovarian tissue at a single center. Read More

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http://dx.doi.org/10.1111/aogs.13616DOI Listing
May 2019
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Birthweight discordance and neonatal morbidity in twin pregnancies: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Mar 22. Epub 2019 Mar 22.

Women's Health and Perinatology Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway.

Introduction: The aim of this systematic review was to quantify the association between birthweight discordance and neonatal morbidity in twin pregnancies.

Material And Methods: Medline, Embase and Cinahl databases were searched. Studies reporting the occurrence of morbidity in twins affected compared to those not affected by birthweight discordance were included. Read More

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http://dx.doi.org/10.1111/aogs.13613DOI Listing
March 2019
1 Read
1.985 Impact Factor

Delivery outcome after trial of labor in nulliparous women 40 years or older-A nationwide population-based study.

Acta Obstet Gynecol Scand 2019 Mar 22. Epub 2019 Mar 22.

Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

Introduction: The number of women postponing childbirth until an advanced age is increasing. Our aim was to study the outcome of labor in nulliparous women ≥40 years, compared with women 25-29 years, after both spontaneous onset and induction of labor.

Material And Methods: The nationwide population-based Swedish Medical Birth Register was used to study the perinatal outcome in nulliparous women with a singleton, term (gestational weeks 37-44), live fetus in cephalic presentation and a planned vaginal delivery from 1992 to 2011. Read More

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http://dx.doi.org/10.1111/aogs.13614DOI Listing
March 2019
2 Reads

Incidence of gynecological fistula and its surgical treatment: A national registry-based study.

Acta Obstet Gynecol Scand 2019 Mar 19. Epub 2019 Mar 19.

Department of Obstetrics and Gynecology, National Treatment Center for Gynecological Fistula, Haukeland University Hospital, Bergen, Norway.

Introduction: Gynecological fistula (affecting female genital organs) leads to involuntary loss of urine or feces. In industrialized societies, fistulas occur mostly as complications of surgery, radiation therapy or inflammatory bowel disease. We sought to determine the incidence of gynecological fistula and type of surgical treatment provided in Norway. Read More

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http://dx.doi.org/10.1111/aogs.13611DOI Listing
March 2019
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Translational research aiming to improve survival of ovarian tissue transplants using adipose tissue-derived stem cells.

Acta Obstet Gynecol Scand 2019 May 13;98(5):665-671. Epub 2019 Apr 13.

Research Center in Gynecology, Institute of Experimental and Clinical Research, Université Catholique de Louvain, Brussels, Belgium.

There is now sufficient evidence to support the feasibility and efficacy of ovarian tissue (OT) cryopreservation and transplantation for both fertility preservation and restoration purposes. However, there are still issues to address regarding the grafting procedure itself, since transplanted tissue suffers massive follicle loss in the early post-grafting period. To improve follicle survival after transplantation, our group recently developed a two-step transplantation technique for OT transplantation in a xenografting model using adipose tissue-derived stem cells (ASCs). Read More

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http://dx.doi.org/10.1111/aogs.13610DOI Listing

A cohort study of 49 933 women with surgically verified endometriosis: Increased incidence of breast cancer below the age of 40.

Acta Obstet Gynecol Scand 2019 Mar 18. Epub 2019 Mar 18.

Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Introduction: The association between endometriosis and breast cancer is unclear. We assessed the risk of breast cancer in women with surgically verified endometriosis, with special focus on the age at cancer diagnosis, time from endometriosis diagnosis and breast cancer histology.

Material And Methods: All women with first endometriosis-associated diagnoses occurring concomitantly with relevant surgical codes during 1987-2012 were retrieved from the Finnish Hospital Discharge Register in Finland. Read More

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http://dx.doi.org/10.1111/aogs.13609DOI Listing
March 2019
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Hysterectomy-corrected cervical cancer mortality rates in Denmark during 2002-2015: A registry-based cohort study.

Acta Obstet Gynecol Scand 2019 Mar 13. Epub 2019 Mar 13.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Introduction: We aimed to describe the cervical cancer mortality rates after correcting for hysterectomy and to evaluate trends over calendar time and by age.

Material And Methods: Using data from nationwide registries, we calculated uncorrected and hysterectomy-corrected cervical cancer mortality rates among women age ≥20 years in Denmark during 2002-2015. We calculated hysterectomy-corrected rates by subtracting post-hysterectomy person-years from the denominator, unless hysterectomy was performed due to cervical cancer. Read More

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http://dx.doi.org/10.1111/aogs.13608DOI Listing
March 2019
5 Reads

Authors' reply: Experience and education matter for residents, as well as for obstetricians and gynecologists.

Acta Obstet Gynecol Scand 2019 Mar 13. Epub 2019 Mar 13.

Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1111/aogs.13607DOI Listing
March 2019
3 Reads

Nordic influence on British obstetrics.

Acta Obstet Gynecol Scand 2019 Apr;98(4):411-412

Nottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1111/aogs.13597DOI Listing

Targeted Rhesus immunoglobulin for RhD-negative women undergoing an induced abortion: A clinical pilot study.

Acta Obstet Gynecol Scand 2019 Mar 12. Epub 2019 Mar 12.

Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Introduction: The aim of this clinical pilot study was to examine the accuracy of noninvasive fetal RHD genotyping in early pregnancy (8  to 11  weeks) and to clarify whether targeted administration of Rhesus immunoglobulin (RhIg) is possible for women undergoing an induced abortion such that unnecessary injections can be avoided. The study examines the correlation between gestational age and the amount of cell-free fetal DNA in maternal plasma, the fetal fraction of DNA and whether transportation time or body mass index affects these parameters.

Material And Methods: Fifty-two RhD-negative women undergoing a surgically induced abortion were included. Read More

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http://doi.wiley.com/10.1111/aogs.13606
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http://dx.doi.org/10.1111/aogs.13606DOI Listing
March 2019
7 Reads

Approved claims for compensation from gynecological patients in Norway-What characterizes the cases? A 14-year nationwide study.

Acta Obstet Gynecol Scand 2019 Mar 12. Epub 2019 Mar 12.

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Introduction: The Norwegian System of Patient Injury Compensation (NPE) evaluates all patient-reported claims in Norway. Our aim was to study the cases from gynecological patients approved by NPE in order to identify the main reasons for the injuries, the consequences of the treatment failure for the women, and the time course when the treatment failure occurred.

Material And Methods: A retrospective, descriptive study of approved gynecological compensation claims during a 14-year period, based on patient files from NPE. Read More

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http://dx.doi.org/10.1111/aogs.13605DOI Listing

Impact of levator muscle avulsions on Manchester procedure outcomes in pelvic organ prolapse surgery.

Acta Obstet Gynecol Scand 2019 Mar 11. Epub 2019 Mar 11.

Department of Gynecology, Oslo University Hospital, Oslo, Norway.

Introduction: Levator ani muscle avulsions potentially increase recurrence after anterior colporrhaphies. We aimed at evaluating the impact of avulsions on anatomical and patient-reported outcomes 1 year after the Manchester procedure for primary anterior compartment pelvic organ prolapse.

Material And Methods: Prospective cohort study of 189 women undergoing the Manchester procedure between October 2014 and January 2017. Read More

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http://dx.doi.org/10.1111/aogs.13604DOI Listing
March 2019
2 Reads

Antibiotic treatment for patients with amniotic fluid "sludge" to prevent spontaneous preterm birth: A historically controlled observational study.

Acta Obstet Gynecol Scand 2019 Mar 5. Epub 2019 Mar 5.

Department of Obstetrics, Paulista School of Medicine (UNIFESP - EPM), Universidade Federal de São Paulo, São Paulo, Brazil.

Introduction: Amniotic fluid "sludge" has been associated with an increased rate of spontaneous preterm delivery before 35 weeks, a higher frequency of clinical and histologic chorioamnionitis in a high-risk population. Only one study evaluating the use of antibiotics in the presence of amniotic fluid "sludge" showed reduced rates of spontaneous preterm birth at <34 weeks. The objective of this study was to evaluate routine antibiotic treatment in the presence of amniotic fluid "sludge" for prevention of preterm delivery. Read More

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http://dx.doi.org/10.1111/aogs.13603DOI Listing
March 2019
3 Reads

Lessons learnt from anonymized review of cases of peripartum hysterectomy by international experts: A qualitative pilot study.

Acta Obstet Gynecol Scand 2019 Mar 2. Epub 2019 Mar 2.

Department of Obstetrics, Rigshospitalet University Hospital, University of Copenhagen, Copenhagen, Denmark.

Severe obstetric complications are not extensively studied and individual cases are used too little and inappropriately in quality improvement activities, due to limited numbers and prioritization of quantitative research. Nordic and European experts performed a qualitative pilot study using anonymized cases of peripartum hysterectomy. It was feasible to anonymize narratives and we learned lessons in the form of themes for improved clinical care and future research. Read More

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http://dx.doi.org/10.1111/aogs.13601DOI Listing
March 2019
1 Read

Elective egg-freezing for an extra opportunity-the sooner the better.

Acta Obstet Gynecol Scand 2019 Mar 2. Epub 2019 Mar 2.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1111/aogs.13600DOI Listing

An audit on a routine antenatal nonstress testing program in pregnant women with preexisting diabetes.

Acta Obstet Gynecol Scand 2019 Mar 2. Epub 2019 Mar 2.

Center for Pregnant Women with Diabetes, Rigshospitalet University Hospital, Copenhagen, Denmark.

Introduction: The objective was to evaluate the effectiveness of routine (planned) antenatal nonstress tests (NSTs) in pregnant women with preexisting diabetes.

Material And Methods: A retrospective single-center study of 642 consecutive pregnancies in women with preexisting diabetes who gave birth to a singleton ≥22 weeks. Weekly planned NSTs were commenced at 33-35 weeks. Read More

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http://dx.doi.org/10.1111/aogs.13602DOI Listing
March 2019
2 Reads

The prevalence and risk factors of fear of childbirth among pregnant women: A cross-sectional study in Ireland.

Acta Obstet Gynecol Scand 2019 Mar 1. Epub 2019 Mar 1.

The Irish Centre for Fetal and Neonatal Translational Research (INFANT Centre), University College Cork, Cork, Ireland.

Introduction: There is growing evidence of the considerable impact of fear of childbirth on women's health and well-being, but prevalence reports of high and severe fear of childbirth and reported risk factors have been inconsistent in various studies. Therefore, this study aimed to determine the prevalence of high and severe fear of childbirth, and to identify risk factors of childbirth fear.

Material And Methods: A cross-sectional study was conducted among a convenience sample of 882 pregnant women attending antenatal care in Cork, Ireland. Read More

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http://dx.doi.org/10.1111/aogs.13599DOI Listing
March 2019
2 Reads

Cellular therapies for the endometrium: An update.

Acta Obstet Gynecol Scand 2019 May 25;98(5):672-677. Epub 2019 Mar 25.

Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet, and Karolinska University Hospital, Solna, Sweden.

An update on the current state of endometrial cell therapies in terms of cell types, mechanisms of action, delivery, safety, regulatory frameworks and future perspectives. This review focuses on clinical trials using angiogenesis-promoting therapies and stromal therapies piloted in the last 10 years for alleviating Asherman's syndrome and long-term infertility. All studies present promising preliminary results, indicating increased endometrial thickness and resumed menstruation. Read More

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http://doi.wiley.com/10.1111/aogs.13598
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http://dx.doi.org/10.1111/aogs.13598DOI Listing
May 2019
4 Reads

Pregnancy after cancer: is it possible and safe for the mother and the child?

Authors:
Niels Kroman

Acta Obstet Gynecol Scand 2019 May 28;98(5):678. Epub 2019 Mar 28.

University Hospital Herlev, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/aogs.13596DOI Listing

Nordic light in assisted reproduction - let it keep shining.

Acta Obstet Gynecol Scand 2019 Mar;98(3):273-274

Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/aogs.13554DOI Listing
March 2019
2 Reads

Changing trends of adverse pregnancy outcomes with maternal age in primipara with singleton birth: a join-point analysis of a multicenter historical cohort study in China in 2011-2012.

Acta Obstet Gynecol Scand 2019 Feb 24. Epub 2019 Feb 24.

Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Introduction: Adverse pregnancy outcomes are related to two opposite maternal factors, youth and aging. However, the change in trend of specific outcomes with childbearing age is unknown. The aim of this study was to investigate the changing trend of various maternal and neonatal outcomes with maternal age from 17 to 44 years. Read More

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http://dx.doi.org/10.1111/aogs.13595DOI Listing
February 2019
3 Reads

Not only residents, but gynaecologists and obstetricians, too….

Acta Obstet Gynecol Scand 2019 Feb 24. Epub 2019 Feb 24.

Department of Obstetrics and Gynaecology, Croydon University Hospital, Croydon, UK.

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http://dx.doi.org/10.1111/aogs.13593DOI Listing
February 2019
2 Reads

Iatrogenic and non-iatrogenic causes of female fertility loss that may indicate fertility preservation.

Acta Obstet Gynecol Scand 2019 May 28;98(5):559-562. Epub 2019 Mar 28.

Department of Obstetrics and Gynecology, Radboud University Medical Center, Nijmegen, the Netherlands.

Due to advances in fertility preservation options and improvements in life expectancy, there is growing need for fertility preservation counseling for women at risk for premature ovarian insufficiency. The aim of this review is to provide an overview of various causes of female fertility loss and to raise awareness for counseling women about their options for fertility preservation. Furthermore, for counseling of women not only at the time of gonadotoxic treatment but also post-treatment and also of women with other benign causes of increased risk for impaired fertility or premature ovarian insufficiency. Read More

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http://dx.doi.org/10.1111/aogs.13594DOI Listing
May 2019
2 Reads

Clinical decision analysis and model-based economic evaluation studies in perinatology: A systematic review.

Acta Obstet Gynecol Scand 2019 Feb 23. Epub 2019 Feb 23.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

Introduction: Perinatology, the study of two individuals that constitute the mother-fetus dyad, poses unique challenges to the conduct of clinical decision analysis (CDA) and economic evaluation (EE) studies. Our objective was systematically to review CDA and model-based EE studies in pregnant women to better understand how these studies have been conducted and reported in perinatology.

Material And Methods: MEDLINE, Embase, Scopus, Web of Science and clinicaltrials. Read More

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http://dx.doi.org/10.1111/aogs.13590DOI Listing
February 2019
1 Read

Future developments: In vitro growth (IVG) of human ovarian follicles.

Authors:
Evelyn E Telfer

Acta Obstet Gynecol Scand 2019 May 5;98(5):653-658. Epub 2019 Apr 5.

Institute of Cell Biology and Genes and Development Group CDBS, University of Edinburgh, Edinburgh, UK.

Removal and storage of ovarian cortical tissue is currently offered to young female cancer patients undergoing potentially sterilizing chemotherapy and/or radiotherapy. For patients at high risk of reintroduction of malignancy through auto-transplantation, the ultimate aim is to achieve complete oocyte development from this tissue in vitro. The ability to develop human oocytes from the earliest follicular stages through to maturation and fertilization in vitro would revolutionize fertility preservation practice. Read More

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http://dx.doi.org/10.1111/aogs.13592DOI Listing
May 2019
1 Read

Prediction models for determining the success of labor induction: A systematic review.

Acta Obstet Gynecol Scand 2019 Feb 22. Epub 2019 Feb 22.

University of Toronto, Toronto, ON, Canada.

Introduction: The purpose of this study was to systematically identify and compare clinical models using universally accessible clinical and demographic factors that were derived and/or validated to predict the success of labor induction with a view to making recommendations for practice.

Material And Methods: MEDLINE, Embase, www.clinicaltrials. Read More

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http://dx.doi.org/10.1111/aogs.13589DOI Listing
February 2019
1.985 Impact Factor

Vaginal or laparoscopic hysterectomy: Do perioperative outcomes differ? A propensity score-matched analysis.

Acta Obstet Gynecol Scand 2019 Feb 22. Epub 2019 Feb 22.

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA, USA.

Introduction: There are assertions that vaginal mode may be the preferred approach of minimally invasive hysterectomy, yet rates of laparoscopic hysterectomy (LH) continue to rise while vaginal hysterectomy (VH) rate remains relatively unchanged. The aim of this study is to compare the perioperative outcomes of LH vs VH.

Material And Methods: We identified women who underwent either LH or VH for benign indications between 2009 and 2015 at a large academic institution. Read More

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http://dx.doi.org/10.1111/aogs.13591DOI Listing
February 2019
1 Read

Immunohistochemical predictive markers of response to conservative treatment of endometrial hyperplasia and early endometrial cancer: A systematic review.

Acta Obstet Gynecol Scand 2019 Feb 21. Epub 2019 Feb 21.

Gynecology and Obstetric Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Progestogens are widely used for the conservative treatment of endometrial hyperplasia and early endometrial cancer. Nevertheless, they do not achieve the regression in all cases. Although several immunohistochemical markers have been assessed to predict the response to treatment, their usefulness is still unclear. Read More

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http://dx.doi.org/10.1111/aogs.13587DOI Listing
February 2019
1.985 Impact Factor

Sonographic lower uterine segment thickness after prior cesarean section to predict uterine rupture: A systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Feb 19. Epub 2019 Feb 19.

Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, ON, Canada.

Introduction: Cesarean section rates are increasing with a decrease in the rate of trial of labor after cesarean section. The objective of this study was to systematically review the predictive characteristics of sonographic measurement of lower uterine segment thickness for uterine rupture during labor.

Materials And Methods: The review was carried out in agreement with PRISMA and SEDATE guidelines. Read More

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http://dx.doi.org/10.1111/aogs.13585DOI Listing
February 2019
3 Reads

Should progesterone and estrogen receptors be assessed for predicting the response to conservative treatment of endometrial hyperplasia and cancer? A systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Feb 19. Epub 2019 Feb 19.

Obstetrics and Gynecology Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Progestins are used as conservative treatment of endometrial hyperplasia (EH) and early endometrial cancer (EEC). We aimed to assess whether immunohistochemical expression of estrogens and progesterone receptors (ER and PR) predicts the treatment response.

Material And Methods: Electronic databases were searched for studies assessing ER and PR expression in EH and EEC treated with progestins. Read More

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http://doi.wiley.com/10.1111/aogs.13586
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http://dx.doi.org/10.1111/aogs.13586DOI Listing
February 2019
13 Reads
1.985 Impact Factor

Neighborhood deprivation and adverse perinatal outcomes in Sweden: A population-based register study.

Acta Obstet Gynecol Scand 2019 Feb 18. Epub 2019 Feb 18.

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Introduction: Neighborhood deprivation has been associated with adverse perinatal outcomes but it is unclear to what extent maternal and social risk factors explain the association and how a stressful environment per se contributes.

Material And Methods: A population-based register study including 218 030 deliveries in Sweden between January 2013 and July 2017 was conducted. Exposure was living in a deprived or severely deprived area defined by the National Operations Department of the Swedish Police Authority. Read More

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http://dx.doi.org/10.1111/aogs.13582DOI Listing
February 2019

Exploring motivations, attitudes and experiences of oocyte donors: A qualitative study.

Acta Obstet Gynecol Scand 2019 Feb 18. Epub 2019 Feb 18.

Department of Obstetrics and Gynecology, Herlev Gentofte Hospital, University of Copenhagen, Herlev, Denmark.

Introduction: The demand for fertility treatment with donated oocytes is increasing in many European countries. In order to offer oocyte donors an attractive treatment, it is necessary to understand the views of the donors. Therefore, the aim of this study was to explore how women who donate oocytes describe their motives and attitudes towards oocyte donation, as well as their experiences with oocyte donation. Read More

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http://dx.doi.org/10.1111/aogs.13583DOI Listing
February 2019
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Survival from cancer in young people: An overview of late effects focusing on reproductive health.

Acta Obstet Gynecol Scand 2019 May 8;98(5):573-582. Epub 2019 Apr 8.

Leeds Institute of Health Research, School of Medicine and Health, University of Leeds, Leeds, UK.

This paper provides a summary of the areas of survival from childhood, teenage and young adult cancers and the significant late effects that can arise from treatment; with particular focus on the area of reproductive health and the impact on both fertility and pregnancy. To complete this review, Web of Science and MEDLINE were used. Search terms included: "survival AND childhood OR teenage OR young adult cancer", "late effects", "childhood cancer", "teenage AND/OR young adult cancer", AND "fertility after cancer" OR "pregnancy AND cancer" OR "fertility preservation". Read More

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http://dx.doi.org/10.1111/aogs.13584DOI Listing
May 2019
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Challenges of fertility preservation in non-oncological diseases.

Acta Obstet Gynecol Scand 2019 May 12;98(5):638-646. Epub 2019 Mar 12.

Research Laboratory on Human Reproduction and Fertility Clinic, CUB-Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Clinicians should provide fertility counseling to all patients receiving gonadotoxic treatment. International scientific societies have mainly focused on oncological patients, and fewer efforts have been made to apply these recommendations to women diagnosed with benign disease (eg benign hematological diseases, autoimmune diseases, and gynecological or genetic disorders). However, these indications account for 8%-13% of the demand for fertility preservation. Read More

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http://dx.doi.org/10.1111/aogs.13577DOI Listing
May 2019
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The efficacy of misoprostol vaginal insert compared with oral misoprostol in the induction of labor of nulliparous women: A randomized national multicenter trial.

Acta Obstet Gynecol Scand 2019 Feb 16. Epub 2019 Feb 16.

Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.

Introduction: Our objective was to compare the efficacy of a 200-μg misoprostol vaginal insert vs oral misoprostol regarding the cesarean section rate and the time interval to vaginal delivery in nulliparous women with unfavorable cervix.

Material And Methods: In this prospective multicenter trial, 283 nulliparous women at term with Bishop score <6 were randomized to induction of labor with either a misoprostol vaginal insert (n = 140) or oral misoprostol (n = 143). In the oral misoprostol group, a 50-μg dose of oral misoprostol was administered every 4 hours up to 3 times during the first day; during the second day, the dose was increased to 100-μg every 4 hours up to 3 times during the first day, if necessary. Read More

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http://dx.doi.org/10.1111/aogs.13580DOI Listing
February 2019
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Prevalence of deaths in a cohort of girls and women with cryopreserved ovarian tissue.

Acta Obstet Gynecol Scand 2019 May 29;98(5):625-629. Epub 2019 Mar 29.

The Fertility Clinic, section 4071, University Hospital of Copenhagen Rigshospitalet, Copenhagen, Denmark.

Introduction: Ovarian tissue cryopreservation (OTC) is increasingly offered to women in need of fertility preservation. However, little is known about the risk of these women dying before they use the preserved material.

Material And Methods: From 1999 to 2016, 927 girls and women underwent OTC in our center, before receiving gonadotoxic treatment. Read More

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http://dx.doi.org/10.1111/aogs.13576DOI Listing
May 2019
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Placental location and pregnancy outcomes in nulliparous women: A population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.

Introduction: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. However, less is known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes. Read More

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http://dx.doi.org/10.1111/aogs.13578DOI Listing
February 2019
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Maternal outcome after complete uterine rupture.

Acta Obstet Gynecol Scand 2019 Feb 14. Epub 2019 Feb 14.

Norwegian National Advisory Unit on Women's Health, Rikshospitalet, Oslo University Hospital, Oslo, Norway.

Introduction: Complete uterine rupture, a rare peripartum complication, is often associated with a catastrophic outcome for both mother and child. However, few studies have investigated large datasets to evaluate maternal outcomes after complete ruptures, particularly in unscarred uteri. This paucity of studies is partly due to the rarity of both the event and the serious outcomes, such as peripartum hysterectomy and maternal death. Read More

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http://dx.doi.org/10.1111/aogs.13579DOI Listing
February 2019
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Biomarkers of ovarian reserve in childhood and adolescence: A systematic review.

Acta Obstet Gynecol Scand 2019 May 5;98(5):563-572. Epub 2019 Mar 5.

Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

Introduction: Certain medical disorders as well as their management may affect gonadal function. Recent advances in the management of these conditions accompanied by the availability and success of methods of fertility preservation has highlighted the need for assessment of ovarian reserve in childhood and adolescence. Serum anti-Mullerian hormone (AMH) and antral follicle count are well established markers of ovarian reserve and serum inhibin has also been used. Read More

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http://dx.doi.org/10.1111/aogs.13574DOI Listing