9,751 results match your criteria Acta Obstetricia et Gynecologica Scandinavica[Journal]


Challenges of fertility preservation in non-oncological diseases.

Acta Obstet Gynecol Scand 2019 Feb 16. Epub 2019 Feb 16.

Research Laboratory on Human Reproduction and Fertility Clinic, CUB-Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Clinicians should provide fertility counseling to all patients receiving gonadotoxic treatment. International scientific societies have mainly focused on oncological patients, and fewer efforts have been made to apply these recommendations to women diagnosed with benign disease (eg benign hematological diseases, auto-immune diseases, and gynecological or genetic disorders). However, these indications account for 8% to 19% of the demand for fertility preservation. Read More

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http://dx.doi.org/10.1111/aogs.13577DOI Listing
February 2019

The efficacy of misoprostol vaginal insert compared with oral misoprostol in the induction of labor of nulliparous women: a randomized national multicenter trial.

Acta Obstet Gynecol Scand 2019 Feb 16. Epub 2019 Feb 16.

Tampere University hospital, Department of Obstetrics and Gynecology, Tampere, Finland.

Introduction: Our objective was to compare the efficacy of a 200-μg misoprostol vaginal insert (MVI) vs oral misoprostol regarding the cesarean section rate and the time interval to vaginal delivery in nulliparous women with unfavorable cervix.

Material And Methods: In this prospective multicenter trial 283 nulliparous women at term with Bishop score < 6 were randomized to induction of labor with either an MVI (n=140) or oral misoprostol (n= 143). Oral misoprostol was administered 50 μg four-hourly up to three times during the first day and 100 μg four-hourly up to three times during the second day, if necessary. Read More

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http://dx.doi.org/10.1111/aogs.13580DOI Listing
February 2019

Prevalence of deaths in a cohort of girls and women with cryopreserved ovarian tissue.

Acta Obstet Gynecol Scand 2019 Feb 15. Epub 2019 Feb 15.

The Fertility Clinic, section 4071, University Hospital of Copenhagen Rigshospitalet, Copenhagen, Denmark.

Introduction: Ovarian tissue cryopreservation (OTC) is increasingly offered to women in need of fertility preservation. However, little is known about the risk of these women dying before they use the preserved material.

Material And Methods: From 1999 to 2016, 927 girls and women underwent OTC in our center, prior to receiving gonadotoxic treatment. Read More

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http://dx.doi.org/10.1111/aogs.13576DOI Listing
February 2019

Placental location and pregnancy outcomes in nulliparous women: A population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.

Introduction: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. Less is however known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes. Read More

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http://dx.doi.org/10.1111/aogs.13578DOI Listing
February 2019

Maternal outcome after complete uterine rupture.

Acta Obstet Gynecol Scand 2019 Feb 14. Epub 2019 Feb 14.

Norwegian National Advisory Unit on Women's Health, Rikshospitalet Oslo University Hospital, Oslo, Norway.

Introduction: Complete uterine rupture, a rare peripartum complication, is often associated with a catastrophic outcome for both mother and child. However, few studies have investigated large data sets to evaluate maternal outcomes after complete ruptures, particularly in unscarred uteri. This paucity of studies is partly due to the rarity of both the event and the serious outcomes, such as peripartum hysterectomy and maternal death. Read More

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http://dx.doi.org/10.1111/aogs.13579DOI Listing
February 2019

Biomarkers of ovarian reserve in childhood and adolescence: a systematic review.

Acta Obstet Gynecol Scand 2019 Feb 13. Epub 2019 Feb 13.

Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.

Introduction: Certain medical disorders as well as their management may affect gonadal function. Recent advances in the management these conditions accompanied by the availability and success of methods of fertility preservation has highlighted the need for assessment of ovarian reserve in childhood and adolescence. Serum anti-Mullerian hormone (AMH) and antral follicle count are well established markers of ovarian reserve and serum inhibin has also been used. Read More

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http://dx.doi.org/10.1111/aogs.13574DOI Listing
February 2019

Time from referral to ovarian tissue cryopreservation in a cohort of Danish women.

Acta Obstet Gynecol Scand 2019 Feb 13. Epub 2019 Feb 13.

Laboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.

Introduction: Young women with a cancer diagnosis often have very little time to decide whether or not to commence on fertility preserving strategies before initiating potentially sterilizing cancer treatment. Minimizing the interval from opting for fertility preservation to completion of the procedure will reduce the potential risk of delaying cancer treatment. In the current study, we have evaluated the period of time from referral to ovarian tissue cryopreservation (OTC) to actual freezing of the tissue in a cohort of Danish women. Read More

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http://dx.doi.org/10.1111/aogs.13575DOI Listing
February 2019

Elective egg freezing without medical indications.

Acta Obstet Gynecol Scand 2019 Feb 13. Epub 2019 Feb 13.

Wales fertility Institute, Cardiff University, Cardiff, UK.

The aim of this review is to provide current knowledge on fertility preservation for nonmedical reasons in women willing to postpone childbearing. The topic is highly debatable starting from the disagreement about its terminology, the number of eggs necessary to predict chances of success, and the safety and socio/ethical point of view. Cost analysis and discrepancies among countries recommendations and regulations are described to confirm the controversies and unsolved issues around this very interesting topic. Read More

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http://dx.doi.org/10.1111/aogs.13573DOI Listing
February 2019

The controversial role of the Ductus Venosus in hypoxic human fetuses.

Acta Obstet Gynecol Scand 2019 Feb 11. Epub 2019 Feb 11.

Department of Clinical Science, Intervention and Technology, Karolinska Institute and Center for Fetal Medicine, Karolinska University Hospital, Stockholm, Sweden.

The ductus venosus plays a critical role in circulatory adaptation to hypoxia in fetal growth restriction, but the mechanisms still remain controversial. Increased shunting of blood through the ductus venosus under hypoxic conditions has been shown in animal and human studies. The hemodynamic laws governing the accelerated flow in this vessel suggest that any dilatation at its isthmus, which increases the blood flow shunting to the heart, is associated with a low, absent or reversed a-wave, and a high pulsatility index. Read More

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http://dx.doi.org/10.1111/aogs.13572DOI Listing
February 2019

Women's perceptions of medication use during pregnancy and breastfeeding - a Swedish cross-sectional questionnaire study.

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

Department of Obstetrics and Gynecology, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Introduction: Medication use for different kinds of symptoms and diseases during pregnancy is common. When counseling the pregnant woman, an understanding of her perceptions concerning the use of medication as well as possible associated anxiety and obstacles is important in order to ensure high adherence to the treatment regimen.

Material And Methods: A questionnaire was developed regarding the use of medication, perceptions on use of medication, as well as perceptions about pregnancy outcomes in association with medication use during pregnancy. Read More

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http://dx.doi.org/10.1111/aogs.13570DOI Listing
February 2019
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A brief history of oocyte cryopreservation: arguments and facts.

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

G.EN.E.R.A. Center for Reproductive Medicine, G.EN.E.R.A. Veneto, Marostica, Italy.

The term "cryopreservation" refers to the process of cooling cells and tissues and storing them at subzero temperatures in order to stop all biologic activity and preserve their viability and physiologic competences for future use. Cooling to subzero temperatures is not a physiological condition for human cells; this is probably due to the high content of water in the living matter, whose conversion to ice crystals may be associated with severe and irreversible damages. Among reproductive cells and tissues, metaphase II oocytes are notably vulnerable to cryopreservation, mainly because of their large size, low surface area to volume ratio, relatively high water content and presence of the meiotic spindle. Read More

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http://dx.doi.org/10.1111/aogs.13569DOI Listing
February 2019
1 Read

Hysterectomy - who should be trained to do it?

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

OLVG locatie OostAmsterdam, Netherlands.

We wish to thank Dr. Matsubara et al. for their valuable response on our Editorial that deals with the important topic whether all residents still need to learn to perform abdominal hysterectomy. Read More

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http://dx.doi.org/10.1111/aogs.13571DOI Listing
February 2019
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Preterm delivery caused by altered microbial environment and HPV infection.

Authors:
Erik Kudela

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

Department of Obstetrics and Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, Slovakia.

I read the original research article by Jar-Allah et al. with great interest (1). They report changes of cervical cytology and its relationship to the risk of preterm delivery in singleton pregnancies in a large cohort. Read More

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http://dx.doi.org/10.1111/aogs.13567DOI Listing
February 2019

Vacuum operator's experience - does it really matter?

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University, Medical Center, Jerusalem, Israel.

We read the study by Bergendahl et al. recently published in this journal with great interest . They performed a retrospective cohort study among nulliparous women delivered by vacuum extraction at a teaching hospital and evaluated the risk for obstetric anal sphincter injury (OASIS) giving specific attention to operator related variables. Read More

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http://dx.doi.org/10.1111/aogs.13568DOI Listing
February 2019

Reply to: Adhesion proteins: suitable therapeutic targets or biomarkers of therapy response for endometriosis?

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Center for Reproductive Medicine, Taipei Medical University Hospital, Taiwan.

We are pleased to read the recent letter to editor by Barra and Ferrero who have been interested in our recent publication in AOGS. In that report, we demonstrated the decreased expression of Tensin 1 (TNS1) in tissue and serum of women with endometriosis after receiving gonadotropin-releasing-hormone agonist (GnRHa) treatment. In our study, we only recruited patients with ovarian endometriosis as mentioned in the material and methods section. Read More

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http://dx.doi.org/10.1111/aogs.13566DOI Listing
February 2019
1 Read

Trial of labor after cesarean section in risk pregnancies: a population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Science, University of Bergen, Norway.

Introduction: In most pregnancies after a cesarean section, a trial of labor is an option. The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate.

Material And Methods: In a cohort study (n=57 109), using data from the Medical Birth Registry of Norway 1989-2014, women with a second delivery after a first pregnancy cesarean section were included. Read More

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http://dx.doi.org/10.1111/aogs.13565DOI Listing
February 2019
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Levonorgestrel intrauterine contraceptive systems (13.5 mg and 52 mg) and risk of ectopic pregnancy.

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.

Introduction: The objective was to investigate the Pearl index for ectopic pregnancy in women using levonorgestrel intrauterine system (LNG-IUS) at time of conception.

Material And Methods: This was a sub-study of a hospital based historical cohort including women with an ectopic pregnancy diagnosed in four referral hospitals in Stockholm Sweden between December 2013 and April 2017. Study participants and type of contraception at time of conception were identified through the electronic medical chart system. Read More

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http://dx.doi.org/10.1111/aogs.13564DOI Listing
February 2019
2 Reads

Induction of labor at full-term in pregnant women with uncomplicated singleton pregnancy: a systematic review and meta-analysis of randomized trials.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: The lowest incidence of perinatal morbidity and mortality occurs around 39-40 weeks.Therefore, some have advocated induction of uncomplicated singleton gestations once they reach full-term. The aim of the study was to evaluate the risk of cesarean delivery and any maternal and perinatal effects of a policy of induction of labor in full-term uncomplicated women with singleton gestations. Read More

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http://dx.doi.org/10.1111/aogs.13561DOI Listing
February 2019
2 Reads
1.985 Impact Factor

The psychological importance of fertility preservation counselling and support for cancer patients.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

School of Women and Children's Health, Faculty of Medicine, University of New South Wales - Sydney, Kensington, NSW, Australia.

Infertility associated with cancer can have significant psychological impacts to cancer patients and survivors, necessitating appropriate fertility-related psychological support. This literature review details the psychological impact of infertility in cancer patients and survivors, and discusses fertility counselling as described in current international guidelines; as either the provision of fertility information or psychosocial support. Fertility counselling has a role in assisting with fertility treatment decision-making, but also in supporting patients with the emotional distress associated with potential infertility at the time of cancer diagnosis, and infertility in survivorship. Read More

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http://dx.doi.org/10.1111/aogs.13562DOI Listing
February 2019
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Low-dose vaginal misoprostol versus vaginal dinoprostone insert for induction of labor beyond 41st week: a randomized trial.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

Unit of Maternal-Fetal Medicine, Department of Obstetrics, Miguel Servet University Hospital, Zaragoza, Spain.

Introduction: The aim of this study was to compare the efficacy and safety of low-dose protocol of vaginal misoprostol and vaginal dinoprostone insert for induction of labor in women with post-term pregnancies.

Material And Methods: We designed a prospective, randomized, open-labeled, blinded for the end-point evaluators trial including women of at least 41 weeks of gestational age with uncomplicated singleton pregnancies and Bishop score lower than 6. They were randomized into dinoprostone or misoprostol groups in a 1:1 ratio. Read More

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http://dx.doi.org/10.1111/aogs.13556DOI Listing
February 2019
2 Reads

A prospective study of women and girls undergoing fertility preservation due to oncologic and non-oncologic indications in Sweden - Trends in patients' choices and benefit of the chosen methods after long-term follow-up.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

Division of Pediatrics, Karolinska Institutet, Stockholm, Sweden.

Introduction: In Scandinavian countries, programs for fertility preservation are offered free of charge at tertiary-care university hospitals to all patients facing treatments with risk of subsequent sterility. In this prospective study we aimed to investigate trends in female patients' choices after counseling and fertility preservation outcomes during follow-up in relation to benign vs malignant indications.

Material And Methods: Data on 1254 females including 1076 adults and 178 girls who received fertility preservation counseling for either oncologic (N=852) or benign indications (N=402) at Karolinska University Hospital, Stockholm, between 1 Oct 1998 and 1 Dec 2018 were analyzed. Read More

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http://dx.doi.org/10.1111/aogs.13559DOI Listing
February 2019

The development of ovarian tissue cryopreservation in Edinburgh: translation from a rodent model through validation in a large mammal and then into clinical practice.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

MRC Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, UK.

Ovarian tissue cryopreservation has developed rapidly from its origins in experiments in sheep in the 1990s, and is now becoming recognised as a standard, rather than experimental, procedure. This review summarises the origins of the technique, and key milestones in its development since the first reported sheep pregnancy in 1994 to the first successful human pregnancy in 2004, and now to the first baby born following cryopreservation of prepubertal ovarian tissue. Many challenges remain to optimise this technique, to improve the survival of follicles within the reimplanted ovarian tissue, to improve its reproducibility and thus success rate and the lifespan of graft. Read More

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http://dx.doi.org/10.1111/aogs.13560DOI Listing
February 2019

Preconceptional TSH level in euthyroid women is inversely associated with the live birth rate in first IVF cycle.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

The Fertility Clinic, Horsens Regional Hospital, Horsens, Denmark.

Introduction: Thyroid disorders have been associated with adverse reproductive outcome. Whether the preconceptional level of thyrotropin (TSH) in euthyroid women impacts on in vitro fertilization (IVF) outcome has been debated. This study reports the outcome of first IVF cycle in euthyroid women in relation to TSH level. Read More

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http://dx.doi.org/10.1111/aogs.13563DOI Listing
February 2019

Is induction of labor a reasonable option for breech presentation?

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

Port Royal Maternity Unit, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France, DHU Risks in Pregnancy, Paris, France; Sorbonne Medical Faculty Paris Descartes UniversityParis, France.

Introduction: Whilst spontaneous onset of labor and vaginal delivery for breech presentation is considered to be a safe and effective option in selected cases, the safety of induction of labor is not established yet. The objectives of this study were to describe the outcomes of pregnancy in women induced with a fetus in breech presentation and compare with those undergoing planned caesarean delivery.

Material And Methods: We performed a secondary analysis of the observational prospective multicenter PREMODA study, including all singleton breech deliveries after 37 weeks in 174 centers in France and Belgium. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13557
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http://dx.doi.org/10.1111/aogs.13557DOI Listing
February 2019
5 Reads

How clinically important are non-D Rh antibodies?

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

The University of Melbourne, Department of Obstetrics and Gynaecology, The Royal Women's Hospital, Parkville, Victoria, Australia.

Introduction: The advent of RhD immunoglobulin prophylaxis to prevent maternal Rh-D alloimmunisation has reduced the incidence of this condition and its associated poor outcomes. Consequently, non-D Rh antibodies now account for a greater proportion of alloimmunised pregnancies. These antibodies have been the subject of comparatively little research. Read More

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http://dx.doi.org/10.1111/aogs.13555DOI Listing
February 2019
1 Read

Balloon catheter for induction of labor in women with one previous cesarean and an unfavorable cervix.

Acta Obstet Gynecol Scand 2019 Feb 5. Epub 2019 Feb 5.

University Medical Center Utrecht, Division Women and Baby, Department of Obstetrics, Birth Center Wilhelmina Children's Hospital, Utrecht, the Netherlands.

Introduction: When women with a previous cesarean section and an unfavorable cervix have an indication for delivery, the choice is to induce labor or perform a cesarean section. This study aims to assess the effectiveness and safety of a balloon catheter as method of induction of labor in women with one previous cesarean section and an unfavorable cervix compared to an elective repeat cesarean section.

Material And Methods: We performed a prospective cohort study in 51 hospitals in the Netherlands on term women with one previous cesarean section, a live singleton fetus in cephalic position, an unfavorable cervix and an indication for delivery. Read More

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http://dx.doi.org/10.1111/aogs.13558DOI Listing
February 2019
2 Reads

Oncologists' and pediatrician oncologists' perspectives and challenges for fertility preservation.

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

International guidelines recommend that health care providers initiate discussions about treatment impact on fertility with cancer patients of reproductive age, or with parents/legal guardians of children, as early as possible in the treatment process. Still, both physicians and patients confirm that this is not always the case. This literature review summarizes findings regarding oncologists' and pediatric oncologists' perspectives and challenges of providing fertility preservation care, and points out directions for development. Read More

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http://dx.doi.org/10.1111/aogs.13551DOI Listing
February 2019

From bench to bedside: Current developments and future possibilities of artificial human ovary to restore fertility.

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Several fertility restoration options are not feasible for some cancer patients, poor responders, and patients with premature ovarian failure who have diminished ovarian reserve. In order to preserve and restore fertility in such patients, new strategies should be offered including artificial human ovary technology. In this mini-review, we explore from bench to bedside the current developments and future possibilities of artificial human ovary technology to restore fertility. Read More

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http://doi.wiley.com/10.1111/aogs.13552
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http://dx.doi.org/10.1111/aogs.13552DOI Listing
February 2019
7 Reads

Management of women with atypical polypoid adenomyoma of the uterus: a quantitative systematic review.

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Atypical polypoid adenomyoma (APA) is an uncommon uterine lesion, which can coexist with endometrial atypical hyperplasia and/or cancer. APA affects premenopausal women in most cases, but it shows high recurrence rate if conservatively treated. To date, the management of patients is based on low quality evidence and not standardized. Read More

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http://dx.doi.org/10.1111/aogs.13553DOI Listing
February 2019
1 Read
1.985 Impact Factor

Maternal short-term complications after planned cesarean delivery without medical indication: a register based study.

Acta Obstet Gynecol Scand 2019 Jan 30. Epub 2019 Jan 30.

Department of Gynecology and Obstetrics, Holbaek Hospital, Holbaek, Denmark.

Introduction: To compare short-term maternal outcomes in healthy primiparous women with uncomplicated pregnancies who delivered a singleton child in term by planned cesarean or planned vaginal delivery.

Material And Methods: Nationwide population-based cohort study of 145 821 low-risk primiparous women with healthy singletons in cephalic position in Denmark, 2008-2016. Data from the Medical Birth Register and the Danish National Patient Registry were linked and compared according to planned mode of delivery. Read More

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http://dx.doi.org/10.1111/aogs.13549DOI Listing
January 2019
3 Reads

Maternal education predicts compliance to exercise during pregnancy.

Acta Obstet Gynecol Scand 2019 Jan 30. Epub 2019 Jan 30.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

We thank Dr Martin-Arias et al for their interest in our study. They are leaders on the study of the effect of exercise in pregnancy, contributing with several, large, important randomized controlled trails on this topic. Exercise during pregnancy has been shown to be associated with different benefits, including a significantly higher incidence of vaginal delivery and a significantly lower incidence of cesarean delivery, gestational diabetes mellitus, hypertensive disorders and with a reduction in the incidence of preterm birht and gestational diabetes mellitus in overweight and obese pregnant women. Read More

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http://dx.doi.org/10.1111/aogs.13550DOI Listing
January 2019
1 Read
1.985 Impact Factor

Postmortem magnetic resonance imaging vs. autopsy of second trimester fetuses terminated due to anomalies.

Acta Obstet Gynecol Scand 2019 Jan 29. Epub 2019 Jan 29.

Centre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden.

Introduction: Our aim was to investigate the accuracy of postmortem fetal magnetic resonance imaging (MRI) compared to fetal autopsy in second trimester pregnancies terminated due to fetal anomalies. A secondary aim was to compare the MRI evaluations of two senior radiologists.

Material And Methods: This was a prospective study including 34 fetuses from pregnancies terminated in the second trimester due to fetal anomalies. Read More

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http://dx.doi.org/10.1111/aogs.13548DOI Listing
January 2019
1 Read

Management and treatment of cervical intraepithelial neoplasia in the Netherlands after referral for colposcopy.

Acta Obstet Gynecol Scand 2019 Jan 28. Epub 2019 Jan 28.

Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.

Introduction: The aim of this study was to describe trends in diagnosis and treatment of women referred from screening with cervical intraepithelial neoplasia (CIN) in the Netherlands, compare this to national guidelines and identify potential areas for improvement for the new primary high-risk HPV screening program.

Material And Methods: We conducted a population-based cohort study using data from Dutch pathology archive. Women aged 29 to 63 years who took part in the Dutch cervical screening program between 1 January 2005 to 31 December 2014 were selected. Read More

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http://dx.doi.org/10.1111/aogs.13547DOI Listing
January 2019
2 Reads

Prediction of large for gestational age infants in pregnancies complicated by obesity: a population based cohort study.

Acta Obstet Gynecol Scand 2019 Jan 28. Epub 2019 Jan 28.

Department of Clinical Science and Education, Unit of Obstetrics and Gynecology, Karolinska Institute, Södersjukhuset hospital, Stockholm, Sweden.

Introduction: Infants born large for gestational age (LGA) have increased risks of adverse perinatal outcomes. Maternal obesity, defined as body mass index (BMI) ≥ 30, is one of the most prevalent risk factors for LGA and the proportion of pregnancies complicated by obesity is increasing. Early identification of women with BMI ≥ 30 at increased risk of giving birth to an LGA infant may open possibilities for prevention, aiming at decreasing the incidence of LGA. Read More

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http://dx.doi.org/10.1111/aogs.13546DOI Listing
January 2019

When will we stop encouraging awareness of fetal movements?

Acta Obstet Gynecol Scand 2019 Feb;98(2):137-138

Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/aogs.13517DOI Listing
February 2019
1 Read

A comparable rate of levator ani muscle injury in operative vaginal delivery (forceps and vacuum) according to the characteristics of the instrumentation.

Acta Obstet Gynecol Scand 2019 Jan 25. Epub 2019 Jan 25.

Department of Obstetrics and Gynecology, Valme University Hospital, Seville, Spain.

Introduction: Forceps delivery is associated with a high rate of levator ani muscle (LAM) trauma (avulsion) at 35-65% while data on avulsion rates after vacuum delivery vary greatly. Nevertheless, a common characteristic of all previous studies carried out to evaluate the association between instrumental deliveries (forceps and vacuum) and LAM-avulsion,is the fact that characteristics of the instrumentation have not been described or evaluated. The objective of this study is to compare the rate of LAM-avulsion between forceps and vacuum-deliveries according to the characteristics of the instrumentation. Read More

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http://dx.doi.org/10.1111/aogs.13544DOI Listing
January 2019
2 Reads

Predicting asymptomatic cervical dilation in pregnant patients with short mid-trimester cervical length: a secondary analysis of a randomized controlled trial.

Acta Obstet Gynecol Scand 2019 Jan 25. Epub 2019 Jan 25.

Division of Maternal Fetal Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: Second trimester asymptomatic cervical dilation is significant risk factor for early preterm birth. The objective of this study is to evaluate whether transvaginal ultrasound cervical length (CL) predicts asymptomatic cervical dilation on physical exam in women with short cervix (CL≤25mm) and no prior preterm birth.

Material And Methods: Secondary analysis of a randomized trial on pessary in asymptomatic singletons without prior preterm birth diagnosed with CL≤25mm between 18 0/7- 23 6/7 weeks. Read More

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http://dx.doi.org/10.1111/aogs.13545DOI Listing
January 2019
1 Read

The role of angiogenic factors in the management of preeclampsia.

Acta Obstet Gynecol Scand 2019 Jan 22. Epub 2019 Jan 22.

Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.

Preeclampsia is a pregnancy disorder causing substantial maternal and fetal morbidity and mortality. In the UK, its diagnosis currently depends upon new onset hypertension and proteinuria. There is a clinical need for enhanced screening to prevent unnecessary resource use and improve outcomes. Read More

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http://dx.doi.org/10.1111/aogs.13540DOI Listing
January 2019
5 Reads

Abnormal cervical cytology is associated with preterm delivery: A population based study.

Acta Obstet Gynecol Scand 2019 Jan 22. Epub 2019 Jan 22.

Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Introduction: Increasing evidence suggests that cervical intraepithelial neoplasia, with or without subsequent treatment, is associated with preterm delivery. We aimed to explore the association between abnormal cervical cytology of different severity and the subsequent obstetric outcomes such as preterm delivery.

Material And Methods: The historical register-based cohort study comprised 19 822 women in the Western Region of Sweden who had at least one abnormal cervical cytology from 1978 to 2012 before the age of 45 and a subsequent singleton delivery. Read More

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http://dx.doi.org/10.1111/aogs.13543DOI Listing
January 2019
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Women receiving massive transfusion due to postpartum hemorrhage: A comparison over time between two nationwide cohort studies.

Acta Obstet Gynecol Scand 2019 Jan 22. Epub 2019 Jan 22.

Center for Clinical Transfusion Research, Sanquin Research, Leiden, the Netherlands.

Introduction: Incidence of massive transfusion after birth was high in the Netherlands between 2004 and 2006 compared with other high-income countries. This study investigated incidence, causes, management and outcome of women receiving massive transfusion due to postpartum hemorrhage in the Netherlands in more recent years.

Material And Methods: Data for all pregnant women who received eight or more units of packed red blood cells from a gestational age of 20 weeks and within the first 24 hours after childbirth, during 2011 and 2012, were obtained from a nationwide retrospective cohort study, including 61 hospitals with a maternity unit in the Netherlands. Read More

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http://dx.doi.org/10.1111/aogs.13542DOI Listing
January 2019
5 Reads

Prevalence of structural birth defects in IVF/ICSI pregnancies resulting from autologous and donor oocytes in Indian sub-continent: results from 2444 births.

Acta Obstet Gynecol Scand 2019 Jan 21. Epub 2019 Jan 21.

Nova-IVI Fertility, Golden Tower, Bangalore, India.

Introduction: This study was conducted to evaluate and compare the incidence of birth defects in in vitro fertilization (IVF)- intracytoplasmic sperm injection (ICSI) pregnancies with autologous and donor oocytes. As a secondary outcome, the prevalence of birth defects in IVF-ICSI pregnancies was compared with those from spontaneous conceptions in India.

Material And Methods: This retrospective study included 2444 births resulting from IVF-ICSI cycles from autologous (n=1743) and donor oocytes (n= 701) during a 3-year period in an Indian infertility center. Read More

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http://dx.doi.org/10.1111/aogs.13541DOI Listing
January 2019
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Hysterectomy: All obstetrician-gynecologists should learn to perform it.

Acta Obstet Gynecol Scand 2019 Jan 20. Epub 2019 Jan 20.

Department of Obstetrics and Gynecology, Jichi Medical University, Tochigi, Japan.

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http://doi.wiley.com/10.1111/aogs.13539
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http://dx.doi.org/10.1111/aogs.13539DOI Listing
January 2019
6 Reads

Prenatal detection of esophageal atresia: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Jan 19. Epub 2019 Jan 19.

Department of Specialist Neonatal and Pediatric Surgery, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.

Introduction: The primary aim of this systematic review was to quantify the diagnostic performance of ultrasound, MRI and amniotic fluid analysis in detecting esophageal atresia (EA) prenatally. The secondary aim was to explore the accuracy of individual imaging signs in identifying this anomaly.

Material And Methods: Medline, Embase and Cochrane databases were searched. Read More

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http://dx.doi.org/10.1111/aogs.13536DOI Listing
January 2019
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Expanding a woman's options to include home use of misoprostol for medical abortion up until 76 days: an observational study of efficacy and safety.

Acta Obstet Gynecol Scand 2019 Jan 19. Epub 2019 Jan 19.

Department of Obstetrics and Gynecology, University Hospital Örebro, Örebro, Sweden.

Introduction: Home use of misoprostol for medical abortion is increasingly being practiced. With gestational length up to 70 days, it is considered effective, safe and acceptable by women. Knowledge of safety and efficacy with longer gestations is limited and studies are required to expand women's options to include this method of abortion. Read More

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http://dx.doi.org/10.1111/aogs.13537DOI Listing
January 2019
2 Reads

Operator experience affects the risk of obstetric anal sphincter injury in vacuum extraction deliveries.

Acta Obstet Gynecol Scand 2019 Jan 19. Epub 2019 Jan 19.

Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

Introduction: Delivery by vacuum extraction is a major risk factor for obstetric anal sphincter injury. The aim of this study was to assess risk factors for obstetric anal sphincter injury in vacuum extraction in nulliparous women, specifically operator-related factors. A secondary aim was to assess other complications of vacuum extraction that are dependent on operator experience. Read More

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http://dx.doi.org/10.1111/aogs.13538DOI Listing
January 2019
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The retropubic tension-free vaginal tape procedure-Efficacy, risk factors for recurrence and long-term safety.

Acta Obstet Gynecol Scand 2019 Jan 19. Epub 2019 Jan 19.

Institute of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Introduction: The retropubic tension-free vaginal tape has been the preferred method for primary surgical treatment of stress urinary incontinence and stress-dominated mixed urinary incontinence in women for more than 20 years. This study presents long-term safety and efficacy data and assesses risk factors for long-term recurrence.

Material And Methods: In a case-series design we assessed a historical cohort of primary surgeries performed with the tension-free vaginal tape procedure in 596 women from 1998 to 2012 with follow up through 2015. Read More

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http://dx.doi.org/10.1111/aogs.13535DOI Listing
January 2019
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Risk of having one lifetime pregnancy and modification by outcome of pregnancy and perinatal loss.

Acta Obstet Gynecol Scand 2019 Jan 16. Epub 2019 Jan 16.

Department of Clinical Science, University of Bergen, Bergen, Norway.

Introduction: With increasing cesarean section rates, adverse pregnancy outcomes such as preterm delivery and small-for-gestational-age continue to be public health challenges. Besides having high co-occurrence and interrelation, it is suggested that these outcomes, along with preeclampsia, are associated with reduced subsequent fertility. On the other hand, the loss of a child during the perinatal period is associated with increased reproduction. Read More

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http://doi.wiley.com/10.1111/aogs.13534
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http://dx.doi.org/10.1111/aogs.13534DOI Listing
January 2019
9 Reads

Adhesion proteins: Suitable therapeutic targets or biomarkers of therapy response for endometriosis?

Acta Obstet Gynecol Scand 2019 Jan 16. Epub 2019 Jan 16.

Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

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http://doi.wiley.com/10.1111/aogs.13533
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http://dx.doi.org/10.1111/aogs.13533DOI Listing
January 2019
5 Reads

Increased diagnostic accuracy of fetal head station by use of transabdominal ultrasound.

Acta Obstet Gynecol Scand 2018 Dec 30. Epub 2018 Dec 30.

Center for Fetal Medicine, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway.

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http://dx.doi.org/10.1111/aogs.13529DOI Listing
December 2018
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Routines for intrapartum fetal monitoring are important, but why and, more importantly, how are they used?

Authors:
Pål Øian

Acta Obstet Gynecol Scand 2018 Dec 30. Epub 2018 Dec 30.

Women's Health and Perinatology Research Group, Department of Clinical Medicine, UiT-The Arctic University of Tromsø and Department of Obstetrics and Gynecology, University Hospital of North Norway, Tromsø, Norway.

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http://dx.doi.org/10.1111/aogs.13530DOI Listing
December 2018
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