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    9452 results match your criteria Acta Obstetricia et Gynecologica Scandinavica[Journal]

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    Decreasing trends in number of depot medroxyprogesterone acetate starters in Norway - a cross-sectional study.
    Acta Obstet Gynecol Scand 2017 Nov 20. Epub 2017 Nov 20.
    Research Group Epidemiology of Chronic Diseases, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
    Introduction: In this study, we examined changes in depot medroxyprogesterone acetate (DMPA) prescriptions over a time-period when new professions started prescribing, and when the method gained some negative media attention.

    Material And Methods: The Norwegian Prescription Database provided data on hormonal contraception from 2006 through 2012. We estimated annual number of DMPA users by calculating doses sold per day/1000 women and calculated, for each contraceptive method on annual basis, a proportion of defined daily doses of all hormonal contraceptives in 5-year age groups at reproductive age. Read More

    Cervical HPV prevalence and genotype distribution in immunosuppressed Danish women.
    Acta Obstet Gynecol Scand 2017 Nov 20. Epub 2017 Nov 20.
    Department of Clinical Medicine, Aarhus University, Aarhus.
    Introduction: Women receiving immunosuppressive treatment due to organ transplantation are at increased risk of Human papilloma virus (HPV)-related diseases, including cervical neoplasia. This pilot study aimed to describe the cervical HPV prevalence and genotype distribution in immunosuppressed Danish women.

    Material And Methods: We included women who underwent renal- (RTR) or bone marrow transplantation (BMTR) in 2009-2012 or 2014 at Aarhus University Hospital, Denmark. Read More

    Long-term evaluation of painful symptoms and fertility after surgery for large rectovaginal endometriosis nodule: a retrospective study.
    Acta Obstet Gynecol Scand 2017 Nov 15. Epub 2017 Nov 15.
    Gynecological Surgery Service, CHU University Hospital Clermont-Ferrand, Clermont-Ferrand.
    Optimal surgical treatment of rectovaginal endometriosis remains a controversial topic. The objective of this study was to evaluate long term postoperative outcomes after rectal shaving or colorectal resection for rectovaginal endometriosis MATERIAL AND METHODS: 195 patients underwent surgery (172 managed by shaving, 23 by colorectal resection) between January 2000 and June 2013 for rectovaginal endometriosis (>2cm) involving at least the serosa of the rectum. Primary outcome measures were pain and fertility. Read More

    Diagnostic accuracy of magnetic resonance imaging in detecting the severity of abnormal invasive placenta: a systematic review and meta-analysis.
    Acta Obstet Gynecol Scand 2017 Nov 14. Epub 2017 Nov 14.
    Department of Obstetrics and Gynaecology, University Hospital of Northern Norway, Tromsø.
    Introduction: Accurate prenatal diagnosis of abnormally invasive placenta (AIP) is fundamental because it significantly reduces maternal morbidities MATERIAL AND METHODS: Medline, Embase, CINAHL and The Cochrane databases were searched. The primary aim of the present review was to elucidate the diagnostic accuracy of prenatal magnetic resonance imaging (MRI) in recognizing the severity of AIP, defined as the depth and topography of invasion. The secondary aim was to ascertain the strength of association between each MRI sign and the depth of placental invasion and to test their individual predictive accuracy in detecting such invasion. Read More

    Very tight versus tight control: which should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials.
    Acta Obstet Gynecol Scand 2017 Nov 10. Epub 2017 Nov 10.
    Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
    Introduction: There is inconclusive evidence from randomized controlled trials (RCTs) to support any specific criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy. Our objective was to analyze the criteria for dose adjustment of pharmacologic treatment for diabetes mellitus (DM) in pregnancy.

    Material And Methods: Data sources: MEDLINE, OVID and Cochrane Library were searched from their inception to September 2017. Read More

    Placental development and function in women with a history of placenta-related complications: a systematic review.
    Acta Obstet Gynecol Scand 2017 Nov 10. Epub 2017 Nov 10.
    Department of Obstetrics and Gynecology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands.
    Introduction: Women with a history of placenta-related pregnancy complications, such as preeclampsia, intra-uterine growth restriction or preterm delivery, have an increased risk for recurrence of such complications. This recurrence is likely the result of underlying endothelial dysfunction that leads to abnormal placentation, especially in complications with an early onset. This study provides an overview of biomarkers of placental development and function in pregnancies from women with a history of pregnancy-related complications. Read More

    Are women positive for the One Step but negative for the Two Step screening tests for gestational diabetes at higher risk for adverse outcomes?
    Acta Obstet Gynecol Scand 2017 Nov 1. Epub 2017 Nov 1.
    Division of Maternal-Fetal Medicine Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
    Introduction: To evaluate if women meeting criteria for gestational diabetes mellitus (GDM) by the One Step test as per International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria but not by other less strict criteria have adverse pregnancy outcomes compared to GDM negative controls. The primary outcome was the incidence of macrosomia, defined as birth weight >4,000 grams.

    Material And Methods: Electronic databases were searched from their inception until May 2017. Read More

    Risk of bowel obstruction during IVF treatment of patients with deep infiltrating endometriosis.
    Acta Obstet Gynecol Scand 2017 Oct 28. Epub 2017 Oct 28.
    Department of Gynecology, Aarhus University Hospital, Aarhus, Denmark.
    Introduction: Women with endometriosis often experience pain and infertility. Medical treatment interferes with the possibility to attain pregnancy. For infertile women with endometriosis surgery is a possible treatment, but with advanced disease there is an increased risk of serious complications. Read More

    Gut microbiome in gestational diabetes: A Cross-sectional study of mothers and offspring 5 years post-partum.
    Acta Obstet Gynecol Scand 2017 Oct 27. Epub 2017 Oct 27.
    Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki.
    Introduction: An altered gut microbiome composition is shown to be associated with various diseases and health outcomes. We compare the gut microbiota of women who developed gestational diabetes mellitus (GDM) to those who did not, and the gut microbiota of their offspring, to determine any differences in the composition and diversity of their gut microbiota, which may be correlated with their GDM state.

    Material And Methods: All women were at high risk for GDM and participated in the Finnish Gestational Diabetes Prevention Study (RADIEL). Read More

    Reproducibility and acceptability of ultrasound measurements of head-perineum distance.
    Acta Obstet Gynecol Scand 2017 Oct 25. Epub 2017 Oct 25.
    National Center for Fetal Medicine, Trondheim University Hospital (St Olavs Hospital), Trondheim.
    Introduction: We aimed to test reproducibility of head-perineum distance (HPD) measurements using two different ultrasound devices and five examiners, to compare ultrasound measurements and clinical assessments and to study if ultrasound examinations were acceptable for women in labor.

    Material And Methods: A reproducibility study was performed at Lund University Hospital, Sweden and Landspitali University Hospital, Iceland from February 2015 to February 2017. The study population comprised 40 healthy women in labor. Read More

    Understanding the associations and significance of fetal movements in overweight or obese pregnant women: a systematic review.
    Acta Obstet Gynecol Scand 2017 Oct 25. Epub 2017 Oct 25.
    Department of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
    Introduction: Presentation with decreased fetal movement (DFM) is associated with fetal growth restriction and stillbirth. Some studies report DFM is frequent amongst overweight or obese mothers. We aimed to determine the significance and associations of fetal movements in women of increased body size. Read More

    Small fetal thymus and adverse obstetrical outcome: a systematic review and a meta-analysis.
    Acta Obstet Gynecol Scand 2017 Oct 23. Epub 2017 Oct 23.
    Department of Clinical Medicine, Faculty of Health Sciences, UiT - the Arctic University of Norway, Tromsø, Norway.
    Introduction: To explore the association between small fetal thymus on ultrasound and adverse obstetrical outcome.

    Material And Methods: Medline, Embase, Cochrane and Web of Science databases were searched. Primary outcome was the risk of preterm birth before 37 and 34 weeks in fetuses with compared to those without a small thymus on ultrasound. Read More

    Pregnancy before recurrent pregnancy loss more often complicated by post-term birth and perinatal death.
    Acta Obstet Gynecol Scand 2017 Oct 21. Epub 2017 Oct 21.
    Department of Obstetrics, Leiden University Medical Center, Leiden, the Netherlands.
    Introduction: The cause of recurrent pregnancy loss often remains unknown. Possibly, pathophysiological pathways are shared with other pregnancy complications.

    Material And Methods: All women with secondary recurrent pregnancy loss (SRPL) visiting Leiden University Medical Center (January 2000-2015) were included in this retrospective cohort to assess whether women with SRPL have a more complicated first pregnancy compared with control women. Read More

    Racial disparities in comorbidity and severe maternal morbidity/mortality in the United States: an analysis of temporal trends.
    Acta Obstet Gynecol Scand 2017 Oct 14. Epub 2017 Oct 14.
    Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
    Introduction: Severe maternal morbidity and mortality have increased in the USA in recent years. This trend has not been consistent across all racial groups. The reasons behind this, and the relation between preexisting conditions, pregnancy-associated disease and severe maternal morbidity/mortality, have not been fully explored. Read More

    Returning to work after laparoscopic myomectomy: a prospective observational study.
    Acta Obstet Gynecol Scand 2017 Oct 14. Epub 2017 Oct 14.
    Department of Gynecology, Whipps Cross University Hospital, London, UK.
    Introduction: Laparoscopic myomectomy offers women many benefits over conventional open surgery, including an expedited recovery and return to employment. Our study evaluates the time taken for women to return to work after laparoscopic myomectomy and identifies factors prolonging recovery to > 8 weeks.

    Material And Methods: We prospectively evaluated 94 women undergoing laparoscopic myomectomy by a single surgeon between January 2012 and March 2015. Read More

    Trends in the incidence rate, type and treatment of surgically verified endometriosis - a nationwide cohort study.
    Acta Obstet Gynecol Scand 2017 Oct 13. Epub 2017 Oct 13.
    Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
    Introduction: To study the trends in incidence rate, type and surgical treatment, and patient characteristics of surgically verified endometriosis during 1987-2012.

    Material And Methods: This is a register-based cohort study. We identified women receiving their first diagnosis of endometriosis in surgery from the Finnish Hospital Discharge Register (FHDR). Read More

    Microdissection testicular sperm extraction in Finland - results of the first 100 patients.
    Acta Obstet Gynecol Scand 2017 Oct 9. Epub 2017 Oct 9.
    Department of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland.
    Introduction: Testicular microdissection sperm extraction (MD-TESE) combined with intracytoplasmic sperm injection (ICSI) has made biological fatherhood possible for many men with the most severe form of male infertility, non-obstructive azoospermia. MD-TESE was introduced in Turku in 2008, and by 2015, 100 Finnish men with non-obstructive azoospermia have been operated on.

    Material And Methods: The average age of the men was 33 years at the time of surgery. Read More

    The menstrual cycle and blood loss during laparoscopic myomectomy.
    Acta Obstet Gynecol Scand 2017 Oct 5. Epub 2017 Oct 5.
    Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA, USA.
    Introduction: Operative morbidity of laparoscopic myomectomy largely relates to the potential for intraoperative blood loss. We sought to determine if blood loss varies according to the menstrual cycle.

    Material And Methods: A retrospective review of 268 women who underwent a laparoscopic myomectomy from 2007 to 2012. Read More

    Obstetrical complications in dichorionic twin pregnancies in women with polycystic ovary syndrome.
    Acta Obstet Gynecol Scand 2017 Oct 5. Epub 2017 Oct 5.
    Department of Gynecology and Obstetrics, Hvidovre University Hospital, Copenhagen, Denmark.
    Introduction: Both women with polycystic ovary syndrome (PCOS) and women with twin pregnancies have increased risk of adverse pregnancy outcome. The aim of this study was to investigate the impact of PCOS and maternal androgen levels on the outcome of dichorionic twin pregnancy.

    Material And Methods: A retrospective study of 360 women with dichorionic twin pregnancies: 72 women with PCOS from a fertility clinic (years 1997-2010) and 288 women without PCOS from a hospital cohort (years 2005-2007). Read More

    Antenatal corticosteroid treatment and placental pathology, with a focus on villous maturation.
    Acta Obstet Gynecol Scand 2017 Oct 5. Epub 2017 Oct 5.
    Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.
    Introduction: Mothers at risk of preterm birth are treated with antenatal corticosteroids, which have advantageous effects for prematurely born infants. Accelerated villous maturation in the placenta is also associated with improved perinatal outcome. The primary aim of this study was to examine the association between antenatal corticosteroids and accelerated villous maturation. Read More

    Differential effect of the ultra-low dose and standard estrogen plus dydrogesterone therapy on thrombin generation and fibrinolysis in postmenopausal women.
    Acta Obstet Gynecol Scand 2017 Oct 5. Epub 2017 Oct 5.
    Department of Gynecological Endocrinology, Jagiellonian University Medical College, Krakow, Poland.
    Introduction: The objective of this study was to estimate the effects of different doses of oral hormone therapy (HT) on thrombin generation and fibrinolytic activity in postmenopausal women after 12 months of treatment.

    Material And Methods: Thrombin generation, fibrinolysis activators and inhibitors were determined before and after 12 months of treatment. Participants (180) were assigned (1:1:1) as follows: (1) standard HT group, 17β-estradiol (1 mg/day) with dydrogesterone (5 mg/day); (2) ultra-low dose HT group, 17β-estradiol (0. Read More

    Diagnostic accuracy of ultrasound in detecting the severity of abnormally invasive placentation: a systematic review and meta-analysis.
    Acta Obstet Gynecol Scand 2017 Sep 30. Epub 2017 Sep 30.
    Women's Health and Perinatology Research Group, Department of Clinical Medicine, Faculty of Health Sciences UiT-The Arctic University of Norway, Tromsø, Norway.
    Introduction: Our objective was to elucidate the overall diagnostic accuracy of ultrasound in detecting the severity of abnormally invasive placentation (AIP).

    Material And Methods: Medline, Embase, CINAHL and The Cochrane databases were searched. The ultrasound signs explored were: loss of hypoechoic (clear) zone in the placental-uterine interface, placental lacunae, bladder wall interruption, myometrial thinning, focal exophitic mass, placental lacunar flow, sub-placental vascularity, and uterovescical hypervascularity. Read More

    Improved neonatal outcome after active management of prolonged pregnancies beyond 41(+2)  weeks in nulliparous, but not among multiparous women.
    Acta Obstet Gynecol Scand 2017 Sep 30. Epub 2017 Sep 30.
    Institution of Clinical Sciences, Department of Obstetrics and Gynecology, University of Lund, Lund, Sweden.
    Introduction: Prolonged pregnancies are associated with adverse maternal and fetal outcome. In Sweden, no national guidelines exist for when to induce prolonged pregnancies.

    Material And Methods: Singleton cephalic prolonged pregnancies (defined as ≥ 41(+3) gestational weeks) during 2001-2013 (n = 199 770) were identified using the Swedish Medical Birth Register. Read More

    The value of oral micronized progesterone in the prevention of recurrent spontaneous preterm birth: a randomized controlled trial.
    Acta Obstet Gynecol Scand 2017 Sep 26. Epub 2017 Sep 26.
    Department of Obstetrics and Gynecology, Ghamra Military Hospital, Cairo, Egypt.
    Introduction: Progesterone is becoming universally accepted for preventing recurrent spontaneous preterm delivery. There is, however, poor consensus on the effective types and doses of progesterone to be used. Despite the encouraging available research, the role of oral micronized progesterone has not yet been thoroughly investigated. Read More

    Weekend-free scheduled IVF/ICSI procedures and single embryo transfer do not reduce live-birth rates in a general infertile population.
    Acta Obstet Gynecol Scand 2017 Sep 20. Epub 2017 Sep 20.
    Reproductive Medicine, Department of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden.
    Introduction: Scheduling of ovum pickup only on weekdays may result in cases of apparently suboptimal timing for human chorionic gonadotropin and ovum pickup. This study aimed to assess whether live-birth rates were reduced in women with a potentially suboptimal day for human chorionic gonadotropin and ovum pickup to avoid weekend work, according to ultrasonographic data on the day of human chorionic gonadotropin planning.

    Material And Methods: An evaluation of the optimal human chorionic gonadotropin priming date was performed in treatment protocols of 1000 consecutive patients undergoing their first in vitro fertilization/intracytoplasmatic sperm injection with single-embryo transfer. Read More

    High birth rates despite easy access to contraception and abortion: a cross-sectional study.
    Acta Obstet Gynecol Scand 2017 Sep 16. Epub 2017 Sep 16.
    Department of Obstetrics and Gynecology, Sahlgrenska Academy at Gothenburg University, Sahlgrenska University Hospital, Gothenburg, Sweden.
    Introduction: The aim was to describe and compare contraceptive use, fertility, birth, and abortion rates in the Nordic countries.

    Material And Methods: National data on births, abortions, fertility rate (1975-2013), redeemed prescriptions of hormonal contraceptives and sales figures of copper intrauterine devices (2008-2013) among women 15-49 years of age in the Nordic countries were collected and analyzed.

    Results: Use of hormonal contraceptives and copper intrauterine devices varied between 31 and 44%. Read More

    Delayed cord clamping and cord gas analysis at birth.
    Acta Obstet Gynecol Scand 2017 Sep 16. Epub 2017 Sep 16.
    Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
    Delayed cord clamping for at least 60 s in both term and preterm babies is a major recent change in clinical care. Delayed cord clamping has several effects on other possible interventions. One of these is the effect of delayed cord clamping on umbilical artery gas analysis. Read More

    Women's experiences of continuous fetal monitoring - a mixed-methods systematic review.
    Acta Obstet Gynecol Scand 2017 Sep 13. Epub 2017 Sep 13.
    Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester.
    Introduction: Antepartum stillbirth is often preceded by detectable signs of fetal compromise, including changes in fetal heart rate and movement. It is hypothesised that continuous fetal monitoring could detect these signs more accurately and objectively than current forms of fetal monitoring and allow for timely intervention. This systematic review aimed to explore available evidence on women's experiences of continuous fetal monitoring to investigate its acceptability prior to clinical implementation and to inform clinical studies. Read More

    Intrapartum transperineal ultrasound used to predict cases of complicated operative (vacuum and forceps) deliveries in nulliparous women.
    Acta Obstet Gynecol Scand 2017 Sep 10. Epub 2017 Sep 10.
    Biostatistics Unit, Department of Preventive Medicine and Public Health, University of Seville, Seville, Spain.
    Introduction: The objective of this study was to investigate the predictive value of intrapartum transperineal ultrasound in the identification of complicated operative(vacuum or forceps) deliveries in nulliparous women.

    Material And Methods: Prospective observational study of nulliparous women with an indication for operative-delivery who underwent intrapartum transperineal ultrasound before fetal extraction. Managing obstetricians were blinded to the ultrasound data. Read More

    Intraoperative cervical treatment does not affect the prevalence of vaginal bleeding 1 year postoperatively after subtotal hysterectomy. A register study from the Swedish National Register for Gynecological Surgery.
    Acta Obstet Gynecol Scand 2017 Sep 2. Epub 2017 Sep 2.
    Department of Obstetrics and Gynecology and Department of Clinical and Experimental Medicine, Faculty of Medicine and Health Science, Linköping University, Linköping, Sweden.
    Introduction: The objectives were to establish the prevalence of persistent vaginal bleeding following subtotal hysterectomy, to analyze the effect of intraoperative cervical treatment on the occurrence of persistent vaginal bleeding, and to evaluate the impact of persistent vaginal bleeding on the patient-reported opinion concerning result of surgery and medical condition.

    Material And Methods: Retrospective study with data from the Swedish National Register for Gynecological Surgery including 5240 women undergoing subtotal hysterectomy for benign conditions between January 2004 and June 2016. Demographic and clinical data were obtained from the pre- and perioperative forms. Read More

    Doppler-based fetal heart rate analysis markers for the detection of early intrauterine growth restriction.
    Acta Obstet Gynecol Scand 2017 Nov 27;96(11):1322-1329. Epub 2017 Sep 27.
    Departments of Biomedical Informatics and Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, USA.
    Introduction: One indicator for fetal risk of mortality is intrauterine growth restriction (IUGR). Whether markers reflecting the impact of growth restriction on the cardiovascular system, computed from a Doppler-derived heart rate signal, would be suitable for its detection antenatally was studied.

    Material And Methods: We used a cardiotocography archive of 1163 IUGR cases and 1163 healthy controls, matched for gestation and gender. Read More

    Propensity score method for analyzing the effect of labor induction in prolonged pregnancy.
    Acta Obstet Gynecol Scand 2017 Aug 21. Epub 2017 Aug 21.
    Public Health, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
    Introduction: There is an ongoing debate on the optimal time of labor induction to reduce the risks associated with prolonged pregnancy.

    Material And Methods: Registry-based study of 212 716 term, singleton cephalic deliveries between 2006 and 2012 in Finland comparing the outcomes of labor induction with those of expectant management in five, three-day gestational age periods between 40 and 42 weeks (group 1: 40(+0) -40(+2) ; group 2: 40(+3) -40(+5) ; group 3: 40(+6) -41(+1) ; group 4: 41(+2) -41(+4) ; group 5: 41(+5) -42(+0) ). Using Poisson regression, induced deliveries in each of the gestational age periods were compared with all ongoing pregnancies. Read More

    Reduced incidence of neonatal early-onset group B streptococcal infection after promulgation of guidelines for risk-based intrapartum antibiotic prophylaxis in Sweden: analysis of a national population-based cohort.
    Acta Obstet Gynecol Scand 2017 Aug 19. Epub 2017 Aug 19.
    Center for Reproductive Epidemiology, Tornblad Institute, University of Lund, Lund, Sweden.
    Introduction: To investigate the incidence of neonatal early-onset group B streptococcal (GBS) infection in Sweden after promulgation of guidelines (2008) for risk factor-based intrapartum antibiotic prophylaxis, and evaluate the presence of risk factors and obstetric management in mothers.

    Material And Methods: National registers were searched for infants with early-onset GBS infection during 2006-2011. Medical records of cases and case mothers were abstracted. Read More

    Mortality and causes of death among women with a history of placental abruption.
    Acta Obstet Gynecol Scand 2017 Nov 19;96(11):1315-1321. Epub 2017 Sep 19.
    Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
    Introduction: Women with a history of placental abruption have an increased later morbidity, but not much is known of the later mortality.

    Material And Methods: Data on women with placental abruption (index cohort) between 1969 and 2005 (n = 7805) were collected from the Finnish Hospital Discharge Register and the Finnish Medical Birth Register. A matched reference cohort consisted of women without placental abruption (n = 23 523). Read More

    Comparing the accuracy of maternal, clinical, and ultrasound estimations to predict birthweight: a meta-analysis.
    Acta Obstet Gynecol Scand 2017 Nov 19;96(11):1289-1299. Epub 2017 Sep 19.
    Department of Medicine and Public Health, Nagoya Medical Science Research Institute, Nagoya, Japan.
    Introduction: Accurate prediction of birthweight prior to delivery is necessary to establish periconceptional strategies to reduce the rates of adverse pregnancy outcomes. This study was performed to determine whether maternal, clinical, or ultrasound estimation provides the best predictor of birthweight.

    Material And Methods: Meta-analysis was performed to summarize the relative ratios of the rate of one of maternal, clinical, and ultrasound estimation within 10% of actual birthweight to that of each of the others within the same range and the difference in correlation coefficient of actual birthweight between clinical and ultrasound estimations. Read More

    Longitudinal transvaginal ultrasound evaluation of cesarean scar niche incidence and depth in the first two years after single- or double-layer uterotomy closure: a randomized controlled trial.
    Acta Obstet Gynecol Scand 2017 Aug 21. Epub 2017 Aug 21.
    Department of Obstetrics, Charité-University Medical Center, Berlin, Germany.
    Introduction: Cesarean deliveries are the most common abdominal surgery procedure globally, and the optimal way to suture the hysterotomy remains a matter of debate. The aim of this study was to assess the incidence of cesarean scar niches and the depth after single- or double-layer uterine closure.

    Material And Methods: We performed a randomized controlled trial in which women were allocated to three uterotomy suture techniques: continuous single-layer unlocked, continuous locked single-layer, or double-layer sutures. Read More

    Complications in operative hysteroscopy - is prevention possible?
    Acta Obstet Gynecol Scand 2017 Aug 18. Epub 2017 Aug 18.
    Department of Gynecology, Hospital St. John of God, Vienna, Austria.
    Operative hysteroscopy in a hospital setting has revolutionized surgical treatment of benign uterine disorders. It is minimally invasive, cost- and time-effective, and may spare patients major surgical interventions. Operative hysteroscopy in a day-case hospital setting is regarded as a safe and well-tolerated procedure with low complication rates. Read More

    Thrombocalc: implementation and uptake of personalized postpartum venous thromboembolism risk assessment in a high-throughput obstetric environment.
    Acta Obstet Gynecol Scand 2017 Nov 21;96(11):1382-1390. Epub 2017 Sep 21.
    Pharmacy Department, Rotunda Hospital, Dublin, Ireland.
    Introduction: Venous thromboembolism risk assessment (VTERA) is recommended in all pregnant and postpartum women. Our objective was to develop, pilot and implement a user-friendly electronic VTERA tool.

    Material And Methods: We developed "Thrombocalc", an electronic VTERA tool using Microsoft EXCEL(™) . Read More

    Declining prevalence of cytological squamous intraepithelial lesions of the cervix among women living with well-controlled HIV - Most women living with HIV do not need annual PAP smear screening.
    Acta Obstet Gynecol Scand 2017 Nov 19;96(11):1330-1337. Epub 2017 Sep 19.
    Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
    Introduction: Cervical screening by means of annual Papanicolaou (PAP) smears has been recommended for all women living with HIV. We analysed the results of our annual PAP smear screening program to identify low-risk subgroups for less rigorous screening.

    Material And Methods: The study comprised 369 women followed at the Helsinki University Hospital 2002-2013, with a total of 2033 PAP smear results. Read More

    Is the incidence of recurrent pregnancy loss increasing? A retrospective register-based study in Sweden.
    Acta Obstet Gynecol Scand 2017 Nov 25;96(11):1365-1372. Epub 2017 Sep 25.
    Fertility Clinic 4071, University Hospital Rigshospitalet, Copenhagen, Denmark.
    Introduction: The aim of this study was to estimate the incidence of recurrent pregnancy loss (RPL). The prevalence of RPL defined as three or more consecutive miscarriages before gestation week 22, is often stated to be 1%. To our knowledge no study has estimated the incidence of RPL, which might be more informative and clinically relevant than the prevalence. Read More

    Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Küster-Hauser syndrome.
    Acta Obstet Gynecol Scand 2017 Nov 21;96(11):1338-1346. Epub 2017 Sep 21.
    Department of Women's Health, Center for Rare Female Genital Malformations, Women's University Hospital, Tübingen University Hospital, Tübingen, Germany.
    Introduction: Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is characterized by congenital absence of the uterus and the upper two-thirds of the vagina in otherwise phenotypically normal females. It is found isolated or associated with renal, skeletal and other malformations. Despite ongoing research, the etiology is mainly unknown. Read More

    Fertility preservation in women with borderline ovarian tumors - how does it impact disease outcome? A cohort study.
    Acta Obstet Gynecol Scand 2017 Nov 21;96(11):1300-1306. Epub 2017 Sep 21.
    Sheba Medical Center, Tel Hashomer, Israel.
    Introduction: Borderline ovarian tumors are typically indolent neoplasms. Since many are diagnosed in younger women, fertility conservation is an important consideration and has been advocated based on retrospective data. The objective of this study was to identify features impacting on recurrence and survival in a series of borderline ovarian tumors, and to assess the safety of a fertility-sparing approach. Read More

    Adjustable mini-sling compared with conventional mid-urethral slings in women with urinary incontinence. A randomized controlled trial.
    Acta Obstet Gynecol Scand 2017 Nov 15;96(11):1347-1356. Epub 2017 Sep 15.
    Department of Obstetrics and Gynecology, Skåne University Hospital, Lund University, Lund, Sweden.
    Introduction: The primary aim of this study was to compare the objective and subjective outcomes and short-term complication rates of an adjustable single-incision mini-sling (SIMS) vs. standard mid-urethral slings (SMUS). The secondary aim was to report pain perception and complications at the one-year follow up. Read More

    Clusters of week-specific maternal gestational weight gain pattern and their association with birthweight: an observational cohort study.
    Acta Obstet Gynecol Scand 2017 Oct;96(10):1251-1260
    Department of Obstetrics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
    Introduction: Gestational weight gain varies widely among different populations, and an inappropriate gestational weight gain is associated with adverse pregnancy outcomes. We aimed to investigate week-specific serial changes in gestational weight gain in an urban Chinese population to derive clusters of gestational weight gain patterns and explore the impact of gestational weight gain patterns on birthweight.

    Material And Methods: This was an observational cohort study of 6130 women delivered at a university hospital in Shanghai, China. Read More

    Maternal and neonatal outcomes following abnormally invasive placenta: a population-based record linkage study.
    Acta Obstet Gynecol Scand 2017 Nov 14;96(11):1373-1381. Epub 2017 Sep 14.
    Clinical and Population Perinatal Health Research, Kolling Institute, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.
    Introduction: Abnormally invasive placenta involves abnormal adherence of the placenta to the myometrium and is associated with severe pregnancy complications such as blood transfusion and hysterectomy. Knowledge of outcomes has been limited by small sample sizes and a focus on maternal rather than neonatal outcomes. This study uses population-level data collected over 10 years to investigate maternal and neonatal outcomes and trends in incidence of abnormally invasive placenta (also known as placenta accreta, increta and percreta). Read More

    Insulin resistance in pregnant women with and without polycystic ovary syndrome, and measures of body composition in offspring at birth and three years of age.
    Acta Obstet Gynecol Scand 2017 Nov 20;96(11):1307-1314. Epub 2017 Sep 20.
    Department of Endocrinology, Odense University Hospital, Odense, Denmark.
    Introduction: Polycystic ovary syndrome is associated with obesity and insulin resistance in the non-pregnant state, but little is known about insulin sensitivity in the pregnant state. Our objective was to compare insulin resistance in pregnant women with and without polycystic ovary syndrome and explore the impact of polycystic ovary syndrome on body composition in offspring at birth and at three years of age.

    Material And Methods: A prospective cohort study including 2548 live-born singleton mother-child pairs residing in Odense municipality, Denmark, during 2010-2013. Read More

    A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway.
    Acta Obstet Gynecol Scand 2017 Oct;96(10):1162-1169
    Department of Gynecologic Oncology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
    Introduction: Gynecological cancer patients are routinely followed up for five years after primary treatment. However, the value of such follow up has been debated, as retrospective studies indicate that first recurrence is often symptomatic and occurs within two to three years of primary treatment. We prospectively investigated time to first recurrence, symptoms at recurrence, diagnostic procedures, and recurrence treatment in gynecological cancer patients after primary curative treatment. Read More

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