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Acta Microbiol Immunol Hung 2020 Apr 24. Epub 2020 Apr 24.

1Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.

A major challenge in the treatment of infections has been the rise of extensively drug resistance (XDR) and multidrug resistance (MDR) in Acinetobacter baumannii. The goals of this study were to determine the pattern of antimicrobial susceptibility, blaOXA and carO genes among burn-isolated A. baumannii strains. Read More

Acta Microbiol Immunol Hung 2020 Mar 30:1-3. Epub 2020 Mar 30.

Department of Medical Microbiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.

MALDI-TOF MS provides fast, easy to perform and cost-effective diagnosis in clinical microbiology laboratories, however in some cases results of MALDI-TOF MS should be confirmed with additional tests. This confirmation is especially important for causes of life-threatening infections like . In our laboratory, three isolates were identified as by Bruker MALDI Biotyper (BD, USA) between April 2018 and March 2019 from clinical specimens of blood, sputum, and urine. Read More

Acta Microbiol Immunol Hung 2020 Mar 30:1-7. Epub 2020 Mar 30.

Aix Marseille University, IRD, APHM, MEPHI, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, 19-21 Boulevard Jean Moulin, 13385 Marseille CEDEX 05, France.

This study aimed to evaluate the routine identification tools available in Lebanon for differentiation of and spp. The identification of 43 isolates defined as spp. by Api 20E was accessed using MALDI-TOF, serological testing, duplex PCR targeting (present in spp. Read More

Acta Microbiol Immunol Hung 2020 Mar 30:1-8. Epub 2020 Mar 30.

Department of Public Health, Faculty of Medicine, University of Szeged, 6720, Dóm tér 10, Szeged, Hungary.

is an emerging zoonotic human pathogen, which is a causative agent of invasive infections in people who are in close contact with infected pigs or contaminated pork products. It is associated with severe systemic infections, most commonly meningitis and sepsis, which may lead to high rates of morbidity and mortality. Serotype 2 is the most prevalent type in infections in humans. Read More

Acta Microbiol Immunol Hung 2020 Mar 30:1-5. Epub 2020 Mar 30.

Departamento de Parasitología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,Ciudad de Méxicoy, México.

shows a high occurrence in the general population, however, its pathologic relevance is still controversial. In this prospective study, we evaluated the prevalence of on eyelashes from 8,033 subjects of a university population (including 7,782 students, and 251 academics). Additional information on some risk factors to infection by the mites was evaluated, as well. Read More

Acta Microbiol Immunol Hung 2020 Mar 26:1-5. Epub 2020 Mar 26.

Diagnostic Laboratory of Clinical Microbiology, Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary.

Our objective was to compare the activity ceftazidime-avibactam (C/A) and ceftolozane-tazobactam (C/T) against multidrug (including carbapenem) resistant clinical isolates collected from six diagnostic centers in Hungary and to reveal the genetic background of their carbapenem resistance.Two hundred and fifty consecutive, non-duplicate, carbapenem-resistant multidrug resistant (MDR) isolates were collected in 2017. Minimal inhibitory concentration values of ceftazidime, cefepime, piperacillin/tazobactam, C/A and C/T were determined by broth microdilution method and gradient diffusion test. Read More

Acta Microbiol Immunol Hung 2020 Mar 9:1-5. Epub 2020 Mar 9.

Department of Biostatistics, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

This study was aimed to evaluate occurrence of antibiotic resistance and the presence of resistance determinants among clinical isolates of . This cross-sectional study from January to September 2018 was performed on 59 strains isolated from clinical samples in the north of Iran. Isolates were identified by standard microbiologic tests and molecular method. Read More

Acta Microbiol Immunol Hung 2020 Mar 9:1-6. Epub 2020 Mar 9.

Department of Clinical Microbiology, Anadolu Medical Center, Gebze, Kocaeli, Turkey.

Objective: The aim of this study was to detect the frequency of methicillin-resistant (MRSA) colonization at admission in a group of presumably high-risk international or Turkish patients referred to our center for elective operations, some of whom were from countries with an unknown prevalence of MRSA infection or colonization.

Methods: The results of nasal swab screening for MRSA colonization performed using a specific algorithm between 2011 and 2018 in a private medical center were retrospectively reviewed. Presence of MRSA was ascertained using culture and/or real-time polymerase chain reaction (real-time PCR). Read More

Acta Microbiol Immunol Hung 2020 Mar 9:1-6. Epub 2020 Mar 9.

Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, 6720, Tisza Lajos krt. 64, Szeged, Hungary.

The biofilm formation by oral bacteria on the implant surface is one of the most remarkable factors of peri-implant infections, which may eventually lead to bone resorption and loss of the dental implant. Therefore, the elimination of biofilm is an essential step for the successful therapy of implant-related infections. In this work we created a basic model to evaluate the antibacterial effect of three widely used antiseptics. Read More

Acta Microbiol Immunol Hung 2020 Mar 9:1-8. Epub 2020 Mar 9.

Department of Microbiology, Medical Research Institute, University of Alexandria, Alexandria, Egypt.

Respiratory infections have a significant impact on health worldwide. Viruses are major causes of acute respiratory infections among children. Limited information regarding its prevalence in Egypt is available. Read More

Acta Microbiol Immunol Hung 2020 Mar 9:1-6. Epub 2020 Mar 9.

Institute of Public Health, 81101, Podgorica, Montenegro.

Tigecycline can be effective to treat infections of carbapenem-resistant (CRAB) however, no interpretive criteria have been approved so far. The objectives of this study were to evaluate the proportion of CRAB isolates and to compare gradient test with a broth microdilution (BMD) method for tigecycline susceptibility testing of .This study included 349 multidrug-resistant (MDR) spp. Read More

Acta Microbiol Immunol Hung 2020 Feb 11:1-7. Epub 2020 Feb 11.

Microbial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.

is the most common cause of chronic infection in human and is associated with gastritis, peptic ulcer disease, and adenocarcinoma of mucosa-associated lymphoid tissue cells. Peptide nucleic acid (PNA) is a synthetic compound, which can inhibit the production of a particular gene. This study aimed to investigate the effect of PNA on inhibiting the expression of A. Read More

Acta Microbiol Immunol Hung 2019 Dec 18:1-5. Epub 2019 Dec 18.

Research Center for Immunodeficiencies (RCID), Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Chronic granulomatous disease is a non-prevalent genetic disorder due to different structural gene mutations encoding components of nicotinamide adenine dinucleotide phosphate oxidase complex. Nicotinamide adenine dinucleotide phosphate oxidase is a complex made by a group of five proteins (subunit) and plays an important role in the innate immune system. Five structural genes are responsible for encoding each subunit, in which cytochrome b-245 alpha chain (also known as p22-phox) is encoded by gene. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-10. Epub 2019 Dec 13.

Department of Biology, College of Education, Salahaddin University, Erbil, Iraq.

is an opportunistic pathogen that is reported as a major cause of nosocomial infections. The aim of this study was to investigate the biofilm formation by clinical and soil isolates, to display their susceptibility to 11 antibiotics and to study a possible relationship between formation of biofilm and multidrug resistance. During 8 months period, from June 2016 to January 2017, a total of 52 clinical and 22 soil isolates of were collected and identified through conventional phenotypic, chromo agar, biochemical tests, API 20E system, and confirmed genotypically by PCR for gene. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-4. Epub 2019 Dec 13.

Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia, Sofia, Bulgaria.

Group A streptococcus (GAS) is a human pathogen causing a broad range of infections, linked with global morbidity and mortality. Macrolide resistance rates vary significantly in different parts of the world. Driving factors of the emergence and spread of resistant clones are not clearly understood. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-9. Epub 2019 Dec 13.

Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Aminoglycosides are widely recommended for treatment of infections in combination with β-lactams or quinolones. This cross-sectional study was aimed to investigate the coexistence of aminoglycoside modifying enzyme (AME) genes among isolates from clinical samples in Ahvaz, Iran. A total of 85 clinical isolates typed by ERIC-PCR were investigated for the presence of AME genes, including , , , , and by PCR. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-5. Epub 2019 Dec 13.

Department of Microbiology and Immunology, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt.

has emerged as an important nosocomial pathogen due to its ability to survive in hospital settings and its antimicrobial resistance. It is one of the key pathogens in ventilator-associated pneumonia (VAP). The aim of this study was to characterize the mechanisms of quinolone resistance among isolates causing VAP and to investigate the presence of the novel gene among them. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-5. Epub 2019 Dec 13.

Institute of Genetics, Microbiology and Biotechnology, Szent István University, Gödöllo, Hungary.

The protista is a free-living amoeba existing in various environments. A number of species among protista are recognized as human pathogens, potentially causing keratitis (AK), granulomatous amoebic encephalitis (GAE), and chronic granulomatous lesions. In this study, 10 rhizosphere samples were collected from maize and alfalfa plants in experimental station at Institute of Genetics, Microbiology and Biotechnology, Szent István University. Read More

Acta Microbiol Immunol Hung 2019 Dec 13:1-10. Epub 2019 Dec 13.

Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany.

We aimed to compare LDH release assay, trypan blue and fluorescent stainings, and non-nutrient plate assay in determining treatment efficacy of antiamoebic agents against trophozoites/cysts, . 1BU trophozoites/cysts were challenged with 0.02% polyhexamethylene biguanid (PHMB), 0. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-3. Epub 2019 Dec 9.

Faculty of Medicine, Department of Medical Microbiology, Hacettepe University, Ankara, Turkey.

is an atypical Gram-negative bacterium that does not grow on MacConkey agar. In this report, we present a 4-year-old female patient with Addison's disease and end-stage renal failure secondary to focal sclerosing glomerulosclerosis. Continuous ambulatory peritoneal dialysis had been performed, and 3 months later, the patient developed fever, diarrhea, and vomiting. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-8. Epub 2019 Dec 9.

Department of Microbiology, Faculty of Medicine, Jagiellonian University Collegium Medicum, Kraków, Poland.

(formerly ) infections (CDIs) are becoming more common and more serious. is the etiologic agent of antibiotic-associated diarrhea, pseudomembranous enterocolitis, and toxic megacolon while CDIs recur in 7.9% of patients. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-8. Epub 2019 Dec 9.

Institute of Clinical Microbiology, University of Szeged, Szeged, Hungary.

In this multicenter study, we aimed to evaluate the performance of MALDI Biotyper and VITEK MS, for identification of species. Three hundred and fourteen clinical isolates, collected in eight European countries between January 2014 and April 2016, were identified at the collecting sites by MALDI Biotyper (versions 3.0 and 3. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-7. Epub 2019 Dec 9.

National Reference Laboratory for Clostridium difficile, Department of Medical Microbiology, Leiden University Medical Center, Leiden, Netherlands.

infections (CDIs) are among the most frequent healthcare-associated infections in Serbia. In 2013, Serbia participated in the European Infection Surveillance Network (ECDIS-Net) who launched a pilot study to enhance laboratory capacity and standardize surveillance for CDI. Two clinics of Clinical Center of Serbia [Clinic for Infectious and Tropical Diseases (CITD) and Clinic of Orthopedic Surgery and Traumatology (COT)] from Belgrade and one general hospital from another metropolitan area of Serbia, Užice, participated. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-5. Epub 2019 Dec 9.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.

Hormones, characteristic to higher ranked animals, are synthesized, stored, and secreted by unicellular eukaryote animals. The unicells also have receptors for recognizing these materials and transmit the message into the cells for provoking response. The hormones are effective in very low concentrations (down to 10-21 M) and opposite effects of lower and higher concentrations can be observed. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-5. Epub 2019 Dec 9.

Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Colistin is one of the most effective alternatives for treating infections. The aim of this study was to determine colistin resistance and heteroresistance rates in from clinical samples in Hacettepe University clinical microbiology laboratory between June 2016 and January 2017. A total of 200 isolates were included in the study. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-7. Epub 2019 Dec 9.

BRULAC-DRC, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.

produces carbapenemase-hydrolyzing class D β-lactamases (CHDLs) as one of the major drug resistance mechanisms. This investigation is thus aimed to assess the prevalence and to characterize the CHDL-producing strains of by both phenotypic assays and genotypic characterization. A total of 73 isolates of were phenotypically and genotypically characterized from patients ( = 1,000) with severe urinary tract infection. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-9. Epub 2019 Dec 9.

Department of Medical Microbiology, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.

Serogroup 6 remains common in the pneumococcal-conjugated vaccine era in Bulgaria; therefore, we investigated its clonal and serotype dynamics. The antibiotic susceptibilities were assessed by broth microdilution. Strains identified as serogroup 6 with latex agglutination method were subjected to serotype-specific PCRs. Read More

Acta Microbiol Immunol Hung 2019 Dec 9:1-5. Epub 2019 Dec 9.

Department of Microbiology, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.

In recent years, colistin has been the drug of choice for treatment of nosocomial infections, especially in bloodstream infections, lower respiratory tract infections, or urinary tract infections. In this study, 65 multidrug-resistant isolated from different clinical samples were included. Minimum inhibitory concentration (MIC) of colistin was detected by broth microdilution method in three different ways. Read More

Acta Microbiol Immunol Hung 2019 Dec;66(4):541-558

Faculty of Optometry, Ramkhamhaeng University, Bangkok, Thailand.

In recent years, microbiota-associated neurodegenerative diseases have been exploited and provided new insight into disease pathogenesis. However, primary open-angle glaucoma (POAG), known as a complex neurodegenerative disease resulting from retinal ganglion cell death and optic nerve damage, can cause irreversible blindness and visual field loss. POAG, which shares several similarities with Parkinson's disease (PD) and Alzheimer's disease (AD), has limited studies and slow progression in the understanding of pathogenesis when compared to PD and AD. Read More

Acta Microbiol Immunol Hung 2019 Dec 11;66(4):529-540. Epub 2019 Nov 11.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

In this study, mechanisms of carbapenem resistance in carbapenem-resistant but cephalosporin-susceptible (Car-R/Ceph-S) were investigated. A total of 243 isolates were studied. The disk diffusion and agar dilution methods were used for determination of antibiotic susceptibility patterns. Read More

Acta Microbiol Immunol Hung 2019 Dec 29;66(4):413-422. Epub 2019 Oct 29.

Microbiology - Biological Sciences Department, Faculty of Pharmacy, University of Porto, Porto, Portugal.

Antimicrobial resistance is a relevant "One Health" issue that shows the need of comparison of isolates of different origins. In this way, guidelines for antimicrobial-resistance evaluation in animals are relevant in relation to human sources. This work aims to compare antimicrobial-resistance results of animal isolates considering CLSI and EUCAST guidelines. Read More

Acta Microbiol Immunol Hung 2019 Dec 29;66(4):423-442. Epub 2019 Oct 29.

Department of Virology, National Public Health Center, Budapest, Hungary.

Zika virus is a mosquito-borne flavivirus with significant public health concern due to its association with neurological symptoms and intrauterine malformations. Although it is endemic in tropical and subtropical areas, sexual transmission raises the possibility of autochthonous spreading elsewhere. We describe the first laboratory diagnosed imported Zika-infections of Hungary, to highlight the challenges of microbiological identification of the pathogen, caused by serological cross-reactivity and short viremia. Read More

Acta Microbiol Immunol Hung 2019 Dec 29;66(4):509-527. Epub 2019 Oct 29.

Department of Microbiology, University of Lagos, Akoka, Nigeria.

Outbreaks of remain a major public health problem globally. This study determined the diversity and antibiotic resistance gene profile of serovars isolated from humans and food animals. Using standard methods, spp. Read More

Acta Microbiol Immunol Hung 2019 Sep;66(3):367-376

Research and Education, Artemis Hospitals, Gurugram, India.

The aim of the study was to find out the carbapenem resistance rate and prevalence of different carbapenemase genes in and from a North Indian corporate hospital that receives both Indian and international patients. A total of 528 clinical isolates of and were included in the study. All isolates that were found resistant to carbapenems by MIC testing (Vitek II Compact) were screened for NDM, OXA-48, VIM, and KPC genes by PCR. Read More

Acta Microbiol Immunol Hung 2019 Dec 29;66(4):443-457. Epub 2019 Jul 29.

Laboratory of Clinical and Experimental Microbiology, The Republican Research and Practical Center for Epidemiology and Microbiology, Minsk, Republic of Belarus.

This study performed an epidemiological survey of strains isolated from patients and from asymptomatic carriers. Altogether, 74 strains (46 invasive and 28 non-invasive) were isolated between February 2011 and May 2018 in different regions of the Republic of Belarus. Serogenotyping was carried out by real-time PCR. Read More

Acta Microbiol Immunol Hung 2019 Dec 14;66(4):469-483. Epub 2019 Jun 14.

Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Methicillin-resistant (MRSA) has emerged as a significant opportunistic pathogen among human immunodeficiency virus (HIV) patients of Ethiopia. This study aimed at delineating the prevalence, antimicrobial resistance, and biofilm-forming potentials of nasally colonized MRSA among HIV patients in the Arba Minch province of Ethiopia. A cross-sectional study was performed in HIV patients who visit anti-retroviral therapy clinic of the Arba Minch Hospital between February and April 2017. Read More

Acta Microbiol Immunol Hung 2019 Dec 14;66(4):499-508. Epub 2019 Jun 14.

Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

is an opportunistic pathogen causing infections related to the usage of implants and medical devices. Pathogenicity of this microorganism is mainly linked to its capability to form biofilm structures. Biofilm formation vastly depends on several factors including different proteins. Read More

Acta Microbiol Immunol Hung 2019 Dec 31;66(4):485-497. Epub 2019 May 31.

Department of Microbiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Human bocavirus (HBoV) was first characterized in nasopharyngeal aspirates from young children with acute respiratory infections. It is prevalent among children with acute wheezing. This study was carried out in order to analyze the infection frequency and coinfection rates of HBoV with respiratory syncytial virus (RSV) and to perform phylogenetic analysis of HBoV in samples of children with acute respiratory infection in Isfahan, Iran. Read More

Acta Microbiol Immunol Hung 2019 Sep 28;66(3):301-306. Epub 2019 May 28.

Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.

Loop-mediated isothermal amplification (LAMP) is a rapid molecular technique that has been introduced into malaria diagnosis. The test is easy to perform and offers high sensitivity. We report a 53-year-old male patient who was hospitalized with fever attacks, chills, and headache caused 9 months after returning from Africa. Read More

Acta Microbiol Immunol Hung 2019 Sep 17;66(3):387-398. Epub 2019 May 17.

Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

The increasing resistance to macrolide, lincosamide, and streptogramin B agents among methicillin-resistant (MRSA) is a worldwide problem for the health community. This study aimed to investigate the prevalence of , and in MRSA strains isolated from burn patients in Ahvaz, southwest of Iran. A total of 76 isolates of were collected from January to May 2017 from Taleghani Burn Hospital in Ahvaz. Read More

Acta Microbiol Immunol Hung 2019 Sep 17;66(3):399-411. Epub 2019 May 17.

Laboratory for Clinical and Experimental Microbiology, The Republican Scientific and Practical Center for Epidemiology and Microbiology, Minsk, Belarus.

The aim of this study was to evaluate the prevalence of genotypes ( and ) directly in gastric biopsy specimens in patients with gastric diseases in Belarus. Gastric biopsies were collected from 461 patients with different gastrointestinal disorders: superficial gastritis (287 subjects), atrophy gastritis (59 subjects), erosive gastritis (47 subjects), duodenal ulcer disease (54 subjects), and stomach ulcer (14 subjects). PCR-based genotyping was used to detect and genes. Read More

Acta Microbiol Immunol Hung 2019 Sep 17;66(3):377-385. Epub 2019 May 17.

Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology, University Hospital "Duilio Casula", University of Cagliari, Monserrato (Cagliari), Italy.

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that can affect major organs possibly leading to life-threatening complications and appears with heterogeneous clinical picture. SLE could present with broad spectrum of clinical and laboratory features that can resemble those of other diseases, such as hemopoietic malignancies, infections, or immune-mediated disorders. Its complexity and protean features overlap with many other diseases, hindering the differential diagnosis. Read More

Acta Microbiol Immunol Hung 2019 Jun 7;66(2):189-202. Epub 2019 May 7.

1 Department of Microbiology, School of Medicine, Iran University of Medical Sciences , Tehran, Iran.

As an important global health challenge, diarrhea kills nearly two million people each year. Postinfectious irritable bowel syndrome (IBS) usually manifests itself as the diarrhea-predominant subtype. Small intestinal bacterial overgrowth has been observed more frequently in patients with IBS compared to healthy controls. Read More

Acta Microbiol Immunol Hung 2019 Dec 5;66(4):459-468. Epub 2019 Mar 5.

Department of Parasitology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

In recent years, increasing dust phenomenon in the west of Iran has led to social, economic, and health concerns. This study aimed to represent the existence and genotyping of spp. in dust phenomenon in Ilam Province, Iran. Read More

Acta Microbiol Immunol Hung 2019 Sep 5;66(3):289-300. Epub 2019 Mar 5.

Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Genus is an opportunistic protozoan that is widely distributed in the environment. Within this genus, numerous species are recognized as human pathogens, potentially causing keratitis (AK). AK is a corneal disease, associated predominantly with contact lens (CL) wear; its epidemiology is related to the specific genotypes. Read More

Acta Microbiol Immunol Hung 2019 Mar 28;66(1):113-130. Epub 2019 Feb 28.

1 Department of Environmental Safety and Ecotoxicology, Szent István University , Gödöllő, Hungary.

The emergence of opportunistic Acinetobacter spp. in healthcare settings poses a significant threat to public health. The major reasons for nosocomial spread of these species are their abilities to develop and transfer drug resistance against various classes of antibiotics. Read More

Acta Microbiol Immunol Hung 2019 Mar 28;66(1):31-55. Epub 2019 Feb 28.

1 Faculty of Tropical Medicine, Department of Microbiology and Immunology Mahidol University , Bangkok, Thailand.

Murine models are suggested as the gold standard for scientific research, but they have many limitations of ethical and logistical concern. Then, the alternative host models have been developed to use in many aspects especially in invertebrate animals. These models are selected for many areas of research including genetics, physiology, biochemistry, evolution, disease, neurobiology, and behavior. Read More

Acta Microbiol Immunol Hung 2019 Sep 26;66(3):327-335. Epub 2019 Feb 26.

Clinical Unit of Microbiology, Department of Microbiology, Hospital Universitario Reina Sofía, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba, Córdoba, Spain.

and are frequently found resistance to aminoglycosides in Turkey. The aim of this study was to investigate aminoglycoside resistance in clinical isolates of and from Turkey using both phenotypic and genotypic methods and screening for the prevalence of gene coding for common aminoglycoside-modifying enzymes (AMEs) and 16S rRNA methylase genes. A total of 88 consecutive, non-duplicated ( = 65) and ( = 23) isolates showing resistance or intermediate resistance to amikacin and/or gentamicin were collected between October 2013 and May 2015 from clinical samples received at Gaziantep Dr. Read More

Acta Microbiol Immunol Hung 2019 Sep 26;66(3):273-287. Epub 2019 Feb 26.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.

Ah-receptors (AhRs) recognize and bind foreign environmental molecules as well as some target hormones of other nuclear receptors. As ligands activate transcription factors, they transmit the information on the presence of these molecules by binding to the DNA, which in turn activate xenobiotic metabolism genes. Cross talk with other nuclear receptors or some non-nuclear receptors also activates or inhibits endocrine processes. Read More

Acta Microbiol Immunol Hung 2019 Jun 26;66(2):261-272. Epub 2019 Feb 26.

3 Department of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Coruh University , Artvin, Turkey.

A carbapenem-resistant strain was isolated in Turkey in 2012 and and genes were observed in this strain. The aim of this study was to investigate transferability of plasmid bearing in and to use whole-genome sequencing in order to understand the genetic context of plasmid. strain was used as donor in conjugation experiments. Read More