987 results match your criteria Acta Microbiologica Et Immunologica Hungarica[Journal]


Bartonella henselae IgM seropositivity in both adult and pediatric patients with diverse clinical conditions in Turkey.

Acta Microbiol Immunol Hung 2021 Mar 2. Epub 2021 Mar 2.

3Department of Bioistatistic, Faculty of Medicine, Medeniyet University, Istanbul, Turkey.

Bartonella henselae is the causative agent of cat scratch disease (CSD). In this study, we aimed to investigate the clinical data of patients with suspicion of CSD and delineate current epidemiological features.A total of 785 patients with suspected CSD were included in the study. Read More

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Spread of NDM-producing Klebsiella pneumoniae in a tertiary Greek hospital.

Acta Microbiol Immunol Hung 2021 Mar 3. Epub 2021 Mar 3.

2Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Bacterial carbapenem resistance, especially when mediated by transferable carbapenemases, is of important public health concern. An increased number of metallo-β-lactamase (MBL)-producing Klebsiella pneumoniae strains isolated in a tertiary hospital in Thessaloniki, Greece, called for further genetic investigation.The study included 29 non-repetitive carbapenem resistant K. Read More

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Diverse efficacy of CarbaNP test among OXA-48 carbapenemase producing Enterobacterales in an endemic region.

Acta Microbiol Immunol Hung 2021 Mar 3. Epub 2021 Mar 3.

3Department of Medical Microbiology, TOBB ETU, Ankara, Turkey.

After the first description of OXA-48 type carbapenemase, it has become endemic in Europe, Mediterranean and North African countries in a short time. OXA-48 carbapenemase is the most difficult type to determine and accurate diagnosis is crucial especially in endemic areas.The CarbaNP test was described as a rapid phenotypic evaluation method of carbapenemases activity. Read More

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Detection of non-polio and polio enteroviruses in Acute Flaccid Paralysis surveillance in Turkey.

Acta Microbiol Immunol Hung 2021 Feb 27. Epub 2021 Feb 27.

4Ministry of Health, General Directorate of Public Health, Ankara, Turkey.

Poliomyelitis was a disease feared worldwide, striking suddenly and paralysing mainly children for life. Monitoring of suspected cases of poliomyelitis is carried out with Acute Flaccid Paralysis (AFP) surveillance in Turkey. This study examines national data of AFP surveillance and the epidemiology of enteroviruses (EV) in Turkey from 2000 to 2019 and gives an overview of the detected serotypes of EVs. Read More

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February 2021

BCG masking phenomena might depend on the species of Mycobacterium.

Acta Microbiol Immunol Hung 2021 Mar 1. Epub 2021 Mar 1.

5Department of Public Health, Institute of Health Sciences, Vilnius University Faculty of Medicine, M.K. Ciurlionio Str. 21, Vilnius, Lithuania.

This study investigated BCG masking dependency on the species of Mycobacterium through the immune response to the mycobacterial region of deletion 1 (RD-1) associated growth affecting proteins (GEP).To evaluate the effects of GEP, 8-week old female BALB/c mice were immunized with either the wild type Mycobacterium bovis (MBGEP) or the ATCC Mycobacterium avium subsp. avium (MAGEP) strain and then subjected to further exposure with Mycobacterium terrae or M. Read More

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Detection of efflux pump genes in multiresistant Acinetobacter baumannii ST2 in Iran.

Acta Microbiol Immunol Hung 2021 Feb 2. Epub 2021 Feb 2.

11Department of Clinical Psychology, Zahedan University of Medical Sciences, Zahedan, Iran.

Acinetobacter baumannii, as a nosocomial pathogen has become a worldwide concern in recent years. In the current study, the resistance to tetracyclines and colistin were assessed in the isolates from different provinces of Iran.During the timeline of this study, a number of 270 isolates of A. Read More

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February 2021

Ceftazidime/avibactam and eravacycline susceptibility of carbapenem-resistant Klebsiella pneumoniae in two Greek tertiary teaching hospitals.

Acta Microbiol Immunol Hung 2021 Jan 29. Epub 2021 Jan 29.

3Medical School, Demokritus University of Thrace, Thessaloniki, Greece.

The present study evaluated the carbapenem resistance mechanisms of Klebsiella pneumoniae strains isolated in two Greek tertiary teaching hospitals and their susceptibility to currently used and novel antimicrobial agents.Forty-seven carbapenem resistant K. pneumoniae strains were collected in G. Read More

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January 2021

Interactions between immune system and the microbiome of skin, blood and gut in pathogenesis of rosacea.

Acta Microbiol Immunol Hung 2021 Jan 29. Epub 2021 Jan 29.

1Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, Hungary.

The increasingly wide use of next-generation sequencing technologies has revolutionised our knowledge of microbial environments associated with human skin, gastrointestinal tract and blood. The collective set of microorganisms influences metabolic processes, affects immune responses, and so directly or indirectly modulates disease. Rosacea is a skin condition of abnormal inflammation and vascular dysfunction, and its progression is affected by Demodex mites on the skin surface. Read More

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January 2021

Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France.

Acta Microbiol Immunol Hung 2021 Jan 27. Epub 2021 Jan 27.

1Aix Marseille University, IRD, AP-HM, SSA, VITROME, Marseille, France.

We aimed to assess the prevalence of pathogenic bacteria and resistance genes in rectal samples collected among homeless persons in Marseille, France. In February 2014 we enrolled 114 sheltered homeless adults who completed questionnaires and had rectal samples collected. Eight types of enteric bacteria and 15 antibiotic resistance genes (ARGs) were sought by real-time polymerase chain reaction (qPCR) performed directly on rectal samples. Read More

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January 2021

Simultaneous detection of Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae by quantitative PCR from CSF samples with negative culture in Morocco.

Acta Microbiol Immunol Hung 2021 Jan 27. Epub 2021 Jan 27.

2Laboratory of Medical Bacteriology, National Institute of Hygiene in Rabat, 27, Avenue Ibn Batouta, B.P. 769, Rabat 10 000, Morocco.

Bacteriological cultures from cerebrospinal fluids (CSF) have less sensitivity and specificity compared to quantitative PCR (RT-PCR), and multiple facts still conduct to the increase of negative culture. The aims of this study are to determine the molecular epidemiology and the simultaneous detection of bacterial meningitis in Morocco by using RT-PCR and compared this molecular approach with culture method to improve the etiological diagnosis of meningitis. The CSFs were collected over one-year period in 2018 in different hospitals covering all regions of the Kingdom of Morocco, from patients with suspected meningitis. Read More

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January 2021

Detection of colistin resistance among multidrug-resistant Klebsiella pneumoniae and Escherichia coli clinical isolates in Turkey.

Acta Microbiol Immunol Hung 2021 Jan 27. Epub 2021 Jan 27.

3Department of Medical Microbiology, Istanbul University-Cerrahpasa School of Medicine, Istanbul, Turkey.

In this study investigation of plasmid-mediated mcr 1-5 resistance genes was performed among multidrug-resistant (MDR) colistin sensitive and resistant Klebsiella pneumoniae and Escherichia coli strains isolated in our laboratory. We aimed to evaluate automated system (Vitek-2), broth microdilution (BMD) reference method and chromogenic media performance. Totally 94 MDR K. Read More

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January 2021

Distribution of enterovirus genotypes detected in clinical samples in Hungary, 2010-2018.

Acta Microbiol Immunol Hung 2020 Dec 5. Epub 2020 Dec 5.

1Department of Virology, National Public Health Center, Budapest, Hungary.

This report provides the findings of a retrospective surveillance study on the emergence and circulation of enteroviruses with their associated clinical symptoms over a nine-year period detected at the National Enterovirus Reference Laboratory in Hungary between 2010-2018.Enterovirus (EV) detection and genotyping were performed directly from clinical samples. From 4,080 clinical specimens 25 EV types were identified with a median age of patients of 5 years and 68% of all cases affected children aged 10 years or younger, although infections occurred in all age-groups. Read More

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December 2020

Identification and antifungal susceptibility of Saprochaete clavata from invasive infections in Turkey.

Acta Microbiol Immunol Hung 2020 Nov 30;67(4):252-257. Epub 2020 Nov 30.

1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey.

Saprochaete clavata is an emerging opportunistic pathogen, that causes life-threatening infections, but there are limited evidence and information about the evaluation of in vitro antifungal susceptibility test results. The aim of this study was to determine S. clavata isolates from clinical specimens and to investigate their in vitro antifungal susceptibility. Read More

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November 2020

Prevalence and molecular epidemiology of ceftaroline non-susceptible methicillin-resistant Staphylococcus aureus isolates, first clinical report from Iran.

Acta Microbiol Immunol Hung 2020 Dec 1. Epub 2020 Dec 1.

1Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major pathogens in Iran with a high prevalence and a high level of antibiotic resistance. Ceftaroline is a fifth generation cephalosporin binding and inhibiting penicillin binding protein (PBP2a).

Methods: In the present study, 228 clinical MRSA isolates were collected from four cities of Iran and their susceptibility to ceftaroline was evaluated by E-test and the disk diffusion method. Read More

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December 2020

Detection of VIM, NDM and OXA-48 producing carbapenem resistant Enterobacterales among clinical isolates in Southern Hungary.

Acta Microbiol Immunol Hung 2020 Dec 1. Epub 2020 Dec 1.

2Institute of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, Semmelweis utca 6., 6725 Szeged, Hungary.

Infections caused by carbapenem-resistant Enterobacterales (CRE) present an important therapeutic problem, as there are limited number of effective therapeutic alternatives available. In this study, phenotypic and genotypic methods were used to characterize carbapenemase-production and other resistance-determinants (AmpC and ESBL-production, efflux pump-overexpression) in 50 isolates (Klebsiella spp. n = 35, Escherichia coli n = 12 and Enterobacter cloacae complex n = 3) collected at the Albert Szent-Györgyi Clinical Center (University of Szeged) between 2014 and 2017. Read More

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December 2020

Helicobacter pylori infection is associated with anemia, weight loss or both conditions among Bulgarian children.

Acta Microbiol Immunol Hung 2020 Dec 1. Epub 2020 Dec 1.

2Specialized Hospital for Active Pediatric Treatment, Medical University of Sofia, "Acad. Ivan Evstatiev Geshov" Blvd, 1606, Sofia, Bulgaria.

Some studies suggested an association between Helicobacter pylori infection and iron-deficiency anemia, however, the link between weight loss and the infection in childhood remains non-established. In a retrospective cohort study, we compared H. pylori positivity rates of Bulgarian children without or with anemia (47 children in each group) or weight loss (45 children in each group) and both conditions (17 children in each group). Read More

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December 2020

Relationship between MLSB resistance and the prevalent virulence genotypes among Bulgarian Staphylococcus aureus isolates.

Acta Microbiol Immunol Hung 2020 Nov 28. Epub 2020 Nov 28.

Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia, Sofia, Bulgaria.

The aim of this study was to investigate the rate of resistance to macrolide-lincosamide-streptogramin B (MLSB) antibiotics, the mechanisms underlying this resistance and to evaluate their relationship with virulence genes profiles of 435 Bulgarian clinical isolates Staphylococcus aureus. The highest resistance was observed to penicillin (96.09%), followed by resistance to erythromycin and clindamycin (34. Read More

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November 2020

Investigation of carbapenem resistant Acinetobacter baumannii ST2 in Iran.

Acta Microbiol Immunol Hung 2020 Nov 28. Epub 2020 Nov 28.

Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.

This study investigated carbapenem resistance among Acinetobacter baumannii isolated from respiratory specimens. Epidemiological relationship of the isolates was also evaluated. In this study, 81 respiratory specimens of A. Read More

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November 2020

Epidemiology and antibiotic resistance profile of bacterial meningitis in Morocco from 2015 to 2018.

Acta Microbiol Immunol Hung 2020 Nov 21;67(4):243-251. Epub 2020 Nov 21.

1Biosafety Level 3 and Research Laboratory, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10 000, Morocco.

Over a 4-year study period from 2015 to 2018, altogether 183 isolates of bacterial meningitis were collected from 12 hospitals covering the entire Moroccan territory. Neisseria meningitidis represented 58.5%, Streptococcus pneumoniae 35. Read More

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November 2020

Clonal spread of PER-1 and OXA-23 producing extensively drug resistant Acinetobacter baumannii during an outbreak in a burn intensive care unit in Tunisia.

Acta Microbiol Immunol Hung 2020 Nov 18;67(4):222-227. Epub 2020 Nov 18.

2Tunis El Manar University, Faculty of Medicine of Tunis, LR18ES39, 1006, Tunis, Tunisia.

Extensively drug resistant Acinetobacter baumannii (XDR-Ab), has emerged as an important pathogen in several outbreaks. The aim of our study was to investigate the eventual genetic relatedness of XDR-Ab strains recovered from burn patients and environment sites in the largest Tunisian Burn Intensive Care Unit (BICU) and to characterize β-lactamase encoding genes in these strains. Between March 04th, 2019 and April 22nd, 2019 an outbreak of XDR-Ab was suspected. Read More

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November 2020

Antibiotic induced biofilm formation of novel multidrug resistant Acinetobacter baumannii ST2121 clone.

Acta Microbiol Immunol Hung 2020 Nov 11. Epub 2020 Nov 11.

2Department of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Gumushane University, Gümüşhane, Turkey.

The aim of this study was to identify antimicrobial resistance and virulence factor genes exhibited by multidrug resistant (MDR) Acinetobacter baumannii, to analyze biofilm formation and to investigate clonal subtypes of isolate. Whole genome sequencing was done by Illumina NovaSeq 6,000 platform and multilocus sequence typing (MLST) was performed by Oxford and Pasteur typing schemes. Influence of imipenem and levofloxacin on biofilm formation was investigated in 96-well plates at 3 replicates. Read More

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November 2020

Emergence of carbapenemase-producing and colistin resistant Klebsiella pneumoniae ST101 high-risk clone in Turkey.

Acta Microbiol Immunol Hung 2020 Nov 9;67(4):216-221. Epub 2020 Nov 9.

2Department of Microbiology, Faculty of Molecular Biology and Genetics, Usak University, 64200, Usak, Turkey.

Carbapenemase-producing and colistin resistant Klebsiella pneumoniae has become a worldwide healthcare problem. This study describes molecular characterization of carbapenemase-producing and colistin resistant clinical K. pneumoniae isolates. Read More

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November 2020

Possible contribution of trained immunity in faulty hormonal imprinting and DOHaD: Review and hypothesis.

Authors:
György Csaba

Acta Microbiol Immunol Hung 2020 Sep 30;67(3):143-147. Epub 2020 Sep 30.

Department of Genetics, Cell-and Immunobiology, Semmelweis University, Budapest, Hungary.

The faulty hormonal imprinting theory (published in 1980) and the DOHaD (Developmental Origin of Health and Disease theory (published in 1986) are twin-concepts: both justify the manifestation after long time (in adults) diseases which had been provoked in differentiating cells (e.g. during gestation). Read More

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September 2020

Upregulation of efrAB efflux pump among Enterococcus faecalis ST480, ST847 in Iran.

Acta Microbiol Immunol Hung 2020 Sep 25;67(3):187-192. Epub 2020 Sep 25.

1Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Antibiotic resistance and especially multiresistance in Enterococci, is a serious public health issue especially in infections of immunocompromised patients. EfrAB is a heterodimeric multidrug ATP-binding cassette (ABC) transporter that causes endogenous resistance to antimicrobials including fluoroquinolones in Enterococcus spp. The aim of this study was to seek the gene expression rate and role of efrAB efflux pump in ciprofloxacin resistant Enterococcus faecalis and Multilocus Sequence Typing (MLST) of multiresistant isolates. Read More

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September 2020

Herd immunization with childhood vaccination may provide protection against COVID-19.

Authors:
Yongqiang Yu

Acta Microbiol Immunol Hung 2020 Sep 26;67(3):198-200. Epub 2020 Sep 26.

1Mindong Hospital, Fuan, Ningde, China.

It may take time to obtain a vaccine for the current COVID-19, and the virus genome may keep an evolution and mutations, so a universal and effective vaccine for the coronavirus may not be possible. Epidemiological studies reveal the infection of SARS and COVID-19 in children is less frequent and less severe than in adults. Childhood vaccine-mediated cross cellular immunity and immunomodulation might provide protection against the infections of COVID-19. Read More

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September 2020

An alternative for urine cultures: Direct identification of uropathogens from urine by MALDI-TOF MS.

Acta Microbiol Immunol Hung 2020 Sep 24;67(3):193-197. Epub 2020 Sep 24.

Department of Medical Microbiology, Faculty of Medicine, Marmara University, Istanbul, Turkey.

Urinary tract infections are one of the most common bacterial infections and rapid diagnosis of the infection is essential for appropriate antibiotic therapy. The goal of our study was to identify urinary pathogens directly by MALDI-TOF MS and to perform antibiotic susceptibility tests in order to shorten the period spent for culturing.Urine samples submitted for culture to the Clinical Microbiology Laboratory were enrolled in this study. Read More

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September 2020

Effects of different decontaminating solutions used for the treatment of peri-implantitis on the growth of Porphyromonas gingivalis-an in vitro study.

Acta Microbiol Immunol Hung 2020 Aug 25. Epub 2020 Aug 25.

2Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Tisza Lajos körút 64-66.,Szeged, Hungary.

Implants have been considered the treatment of choice to replace missing teeth, unfortunately, peri-implant disease is still an unresolved issue. Contaminated implants may be decontaminated by physical debridement and chemical disinfectants; however, there is a lack of consensus regarding the ideal techniques/agents to be used for the decontamination. The objective of our study was to compare the decontaminating efficacy of different chemical agents on a titanium surface contaminated with Porphyromonas gingivalis, a typical representative of the bacterial flora associated with peri-implantitis. Read More

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Amiodarone that has antibacterial effect against human pathogens may represent a novel catheter lock.

Acta Microbiol Immunol Hung 2020 Jul 6;67(2):133-137. Epub 2020 Jul 6.

1Department of Medical Microbiology, Medical School, University of Pecs, Pecs, Hungary.

Infection is one of the most feared hospital-acquired complications. Infusion therapy is frequently administered through a central line. Infusions facilitating bacterial growth may be a source of central line-associated bloodstream infections. Read More

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Passive immunization: Paradoxical and traditional method for new pandemic challenge COVID-19.

Acta Microbiol Immunol Hung 2020 Jul 3;67(2):87-90. Epub 2020 Jul 3.

Department of Zoology, Government College University Faisalabad, Faisalabad, Pakistan.

World has been suffering from pandemic caused by mysterious Coronavirus. The novel member of Coronaviridae causing COVID-19 disease is named as SARS-Cov-2. Its first case was reported in China by the end of 2019, but its exponential spread has wrapped entire globe, suspended and is penalizing mankind. Read More

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Low prevalence of hypervirulent Klebsiella pneumoniae in Anatolia, screened via phenotypic and genotypic testing.

Acta Microbiol Immunol Hung 2020 Jul 3;67(2):120-126. Epub 2020 Jul 3.

2Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Hypervirulent Klebsiella pneumoniae (hvKP) strains are associated with vigorous clinical presentation and relapses. Initially reported from Asia, these variants have spread globally and become an emerging agent of significant health threat. This study was carried out to identify hvKP strains in a previously uninvestigated region and to evaluate the impact of commonly-employed phenotypic and genotypic markers as diagnostic assays. Read More

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