688,536 results match your criteria Acta Metallurgica Sinica[Journal]


Effect of tunable π bridge on two-photon absorption property and intramolecular charge transfer process of polycyclic aromatic hydrocarbons.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 20;259:119830. Epub 2021 Apr 20.

Department of Physics, Harbin Institute of Technology, Harbin 150001, China.

The influences of the conjugation effect on the charge transfer and nonlinear optical (NLO) properties of polycyclic aromatic hydrocarbons (PAHs) are comprehensively investigated at the microscopic molecular level. We found that the conjugation effect of π bridge is negatively correlated with molecular planarity, excitation energy, two-photon absorption (TPA) cross-section, and the second hyperpolarizability. For the first time, the charge transfer matrix (CTM) is applied to the molecular two-photon transition process. Read More

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Novel luteolin sensor of tannic acid-stabilized copper nanoclusters with blue-emitting fluorescence.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 30;259:119887. Epub 2021 Apr 30.

College of Arts, Taiyuan University of Technology, Jinzhong, 030600, Shanxi, China. Electronic address:

In this work, the fluorescent copper nanoclusters (Cu NCs) were firstly adopted to detect luteolin with excellent performance. The blue-emitting Cu NCs was successfully prepared through a facile one-pot approach by protection of tannic acid (TA) and chemical reduction of ascorbic acid (AA). The water-soluble nanoclusters possessed uniform size and displayed good stability. Read More

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Ethanol-extraction SERS strategy for highly sensitive detection of poisons in oily matrix.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 30;259:119883. Epub 2021 Apr 30.

Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. Electronic address:

The sensitive detection and identification of toxicants in oily matrices have suffered from difficulty in poisoning incidents, therefore it is necessary to develop the rapid and efficient analytical method to realize the on-site screening and analyzing. In this report, the surface-enhanced Raman spectroscopy (SERS) method was used to detect paraquat and diquat poisons in various oily matrix coupled with solvent extraction. The solvent extraction not only remove interfering impurities of oily substrates, but also can enrich and separate the poisons from oily matrix. Read More

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Dynamic confocal Raman spectroscopy of flowing blood in bionic blood vessel.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 29;259:119890. Epub 2021 Apr 29.

Shandong Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment, School of Space Science and Physics, Institute of Space Sciences, Shandong University, Weihai, Shandong 264209, China.

How to quickly and safely identify blood species has always been an urgent problem for scientists. Smear test method has the risk of blood contamination, and the blood itself may carry some unknown viruses or pathogens, which will bring health risks to the testing personnel. Therefore, in order to meet the urgent needs of rapid and safe detection of blood, a technology which can detect dynamic confocal Raman spectroscopy of flowing blood in bionic blood vessel was proposed. Read More

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Bisphenol-based cyanide sensing: Selectivity, reversibility, facile synthesis, bilateral "OFF-ON" fluorescence, C structural and conformational analysis.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 26;259:119881. Epub 2021 Apr 26.

Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Graduate School of Energy, Environment, Water and Sustainability (EEWS), KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea; Advanced Membranes and Porous Materials (AMPM) Center, Physical Science & Engineering, King Abdullah University of Science and Technology (KAUST), 4700 Thuwal, 23955-6900 Kingdom of Saudi Arabia. Electronic address:

A structurally characterized novel dual-pocketed tetra-conjugated bisphenol-based chromophore (fluorescence = 652 nm) was synthesized in gram scale in ~90% yield from its tetraaldehyde. Highly selective, naked-eye detection of CN (DMSO/HO) was confirmed by interferent testing. A detection limit of 0. Read More

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Detection of chlorophyll fluorescence parameters of potato leaves based on continuous wavelet transform and spectral analysis.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 2;259:119768. Epub 2021 Apr 2.

Key Laboratory of Modern Precision Agriculture System Integration Research, Ministry of Education, China Agricultural University, Beijing 100083, China. Electronic address:

The tuber development and nutrient transportation of potato crops are closely related to canopy photosynthesis dynamics. Chlorophyll fluorescence parameters of photosystem II, especially the maximum quantum yield of primary photochemistry (Fv/Fm), are intrinsic indicators for plant photosynthesis. Rapid detection of Fv/Fm of leaves by spectroscopy method instead of time-consuming pulse amplitude modulation technique could help to indicate potato development dynamics and guide field management. Read More

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Infrared spectroscopy quantification of functional carbon groups in kerogens and coals: A calibration procedure.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 24;259:119853. Epub 2021 Apr 24.

ICS, CNRS, Université de Strasbourg, BP 296 R8, 670008 Strasbourg, France.

The determination of the abundances of the CH, C = O and aromatic groups in chondritic Insoluble Organic Matter (IOM) and coals by Infrared (IR) spectroscopy is a challenging issue due to insufficient knowledge on the absorption cross-sections and their sensitivity to the molecular environment. Here, we report a calibration approach based on a C synthetic model material whose composition was unambiguously determined by Direct-Pulse/Magic Angle Spinning Nuclear Magnetic Resonance (DP/MAS NMR). Ratios of the cross-sections of the CH, C = O and aromatic groups have been determined, and the method has been applied to IOM samples extracted from four chondrites as Orgueil (CI), Murchison (CM), Tagish Lake (C2-ungrouped) and EET 92042 (CR2), and to a series of coals. Read More

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Innovative use of σ and π electron acceptors in the development of three high throughput 96-microwell spectrophotometric assays for crizotinib.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 30;259:119884. Epub 2021 Apr 30.

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

Crizotinib (CZT) is a potent and selective tyrosine kinase inhibitor used for treatment of non-small cell lung cancer (NSCLC). The development of high-throughput assays for its quality control (QC) is very essential to assure its therapeutic benefits. CZT molecule has multiple electron-donating atoms that can contribute to the formation of colored charge-transfer (CT) complex with iodine as σ-electron acceptor and with 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone (CHBQ) and 7,7,8,8-tetracyanoquinodimethane (TCNQ) as π-electron acceptors. Read More

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Comment on the paper "Improving Poor Man's Kramers-Kronig analysis and Kramers-Kronig constrained variational analysis".

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 28;259:119849. Epub 2021 Apr 28.

Laboratoire Charles Coulomb, UMR5221 CNRS-Université de Montpellier, 34095 Montpellier, France.

The title paper [Spectrochim. Acta A213 (2019): 391-396] reports an improvement of the "Poor Man's Kramers-Kronig analysis" and of the "Kramers-Kronig constrained variational analysis" thanks to an ad hoc modification of some analytical formulas existing in the literature. This ad hoc modification is not based on mathematical grounds. Read More

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Cell-to-cell heterogeneity of phosphate gene expression in yeast is controlled by alternative transcription, 14-3-3 and Spl2.

Biochim Biophys Acta Gene Regul Mech 2021 May 7:194714. Epub 2021 May 7.

Institute of Biology, Leiden University, Leiden, the Netherlands. Electronic address:

Dependent on phosphate availability the yeast Saccharomyces cerevisiae expresses either low or high affinity phosphate transporters. In the presence of phosphate yeast cells still express low levels of the high affinity phosphate transporter Pho84. The regulator Spl2 is expressed in approximately 90 percent of the cells, and is not expressed in the remaining cells. Read More

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Recent advancements in therapeutic targeting of the Warburg effect in refractory ovarian cancer: A promise towards disease remission.

Biochim Biophys Acta Rev Cancer 2021 May 7:188563. Epub 2021 May 7.

Amity Institute of Molecular Medicine and Stem Cell Research, Amity University, Sector-125, Noida, Uttar Pradesh 201303, India. Electronic address:

Epithelial ovarian cancer, the most lethal gynecological malignancy, is diagnosed at advanced stage, recurs and displays chemoresistance to standard chemotherapeutic regimen of taxane/platinum drugs. Despite development of recent therapeutic approaches including poly-ADP ribose polymerase inhibitors, this fatal disease is diagnosed at advanced stage and heralds strategies for early detection and improved treatment. Recent literature suggests that high propensity of ovarian cancer cells to consume and metabolize glucose via glycolysis even in the presence of oxygen (the 'Warburg effect') can significantly contribute to disease progression and chemoresistance and hence, it has been exploited as novel drug target. Read More

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Mutations in cis that affect mRNA synthesis, processing and translation.

Biochim Biophys Acta Mol Basis Dis 2021 May 7:166166. Epub 2021 May 7.

Sanquin Blood Supply Organization, Dept. of Blood Cell Research, and Landsteiner Laboratory, Amsterdam University Medical Centre, location AMC, University of Amsterdam, Amsterdam, The Netherlands.

Genetic mutations that cause hereditary diseases usually affect the composition of the transcribed mRNA and its encoded protein, leading to instability of the mRNA and/or the protein. Sometimes, however, such mutations affect the synthesis, the processing or the translation of the mRNA, with similar disastrous effects. We here present an overview of mRNA synthesis, its posttranscriptional modification and its translation into protein. Read More

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Exploring lipid-dependent conformations of membrane-bound α-synuclein with the VDAC nanopore.

Biochim Biophys Acta Biomembr 2021 May 7:183643. Epub 2021 May 7.

Section on Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Regulation of VDAC by α-Synuclein (αSyn) is a rich and instructive example of protein-protein interactions catalyzed by a lipid membrane surface. αSyn, a peripheral membrane protein involved in Parkinson's disease pathology, is known to bind to membranes in a transient manner. αSyn's negatively charged C-terminal domain is then available to be electromechanically trapped by the VDAC β-barrel, a process that is observed in vitro as the reversible reduction of ion flow through a single voltage-biased VDAC nanopore. Read More

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Oral immunization with recombinant Lactobacillus plantarum expressing Nudix hydrolase and 43 kDa proteins confers protection against Trichinella spiralis in BALB/c mice.

Acta Trop 2021 May 7:105947. Epub 2021 May 7.

College of Veterinary Medicine, Jilin Agricultural University, Changchun, China; Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Agricultural University, Changchun, China; Key Laboratory of animal production and product quality safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address:

Trichinellosis is a significant food-borne zoonotic parasitic disease caused by parasite Trichinella. Given the side effects of anti-Trichinella drugs (e.g. Read More

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Levels and trends in Chagas disease-related mortality in Brazil, 2000-2019.

Acta Trop 2021 May 7:105948. Epub 2021 May 7.

Institute of Studies in Public Health, Federal University of Rio de Janeiro, Avenida Horácio Macedo, S/N, Ilha do Fundão - Cidade Universitária, 21941-598 Rio de Janeiro, Rio deJaneiro, Brazil; Department of Epidemiology, Social Medicine Institute, State University of Rio de Janeiro, Rua São Francisco Xavier 524, Maracanã, 20550-013 Rio de Janeiro, Rio de Janeiro, Brazil.

Chagas disease remains an important public health problem with high morbidity and mortality in several Latin American countries. This nationwide population-based ecological study analyzes the epidemiological characteristics and time trends of Chagas disease-related mortality in Brazil, 2000-2019. We included all deaths reported in Brazil in which Chagas disease was mentioned in the death certificate either as an underlying or associated cause of death (multiple causes of death). Read More

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Current and Future Challenges in Quality Assurance in Molecular Diagnostics.

Clin Chim Acta 2021 May 7. Epub 2021 May 7.

CPDP Consulting, LLC, Denver, Colorado, USA.

The development and performance of molecular genetic assays has required increasingly complex quality assurance in recent years and continues to pose new challenges. Quality management officers, as well as academic and technical personnel are confronted with new molecular genetic parameters, methods, changing regulatory environments, questions regarding appropriate validation, and quality control for these innovative assays that are increasingly applying quantification and/or multiplex formats. Yet, quality assurance and quality control guidelines are still not widely available or in some circumstances have become outdated. Read More

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Peroxide stimulated transition between the ferryl intermediates of bovine cytochrome c oxidase.

Biochim Biophys Acta Bioenerg 2021 May 7:148447. Epub 2021 May 7.

Center for Interdisciplinary Biosciences, Technology and Innovation Park, University of P. J. Safarik, Jesenna 5, 041 54 Kosice, Slovak Republic. Electronic address:

During catalysis of cytochrome c oxidases (CcO) several ferryl intermediates of the catalytic heme a-Cu center are observed. In the P ferryl state, produced by the reaction of two-electron reduced CcO with O, the ferryl iron of heme a and a free radical are present at the catalytic center. The radical reduction stimulates the transition of the P into another ferryl F state. Read More

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Do 'The Four Principles' Apply to the Improvement of Short-Term Clinical Electives?

Acta Med Port 2021 Mar 1;34(3):238. Epub 2021 Mar 1.

Department of Forensic Medicine. Faculty of Medicine. Hokkaido University. Kita-ku. Sapporo. Hokkaido. Japan.

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[COVID-19 and People with Dementia: A Silent Pandemic?]

Acta Med Port 2021 Mar 1;34(3):242. Epub 2021 Mar 1.

Serviço de Psiquiatria Geriátrica. Centro Hospitalar Psiquiátrico de Lisboa. Lisboa. Portugal.

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[Teleworking: What Are the Mental Health Consequences?]

Authors:
Pedro Afonso

Acta Med Port 2021 Mar 1;34(3):241. Epub 2021 Mar 1.

Clínica Universitária de Psiquiatria e Psicologia Médica. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal.

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[What Makes a Pediatrician a Neonatologist].

Authors:
Daniel Virella

Acta Med Port 2021 Mar 1;34(3):240. Epub 2021 Mar 1.

Unidade de Cuidados Intensivos Neonatais. Hospital Dona Estefânia. Centro Hospitalar Universitário de Lisboa Central. Lisboa. Portugal.

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[Scrofuloderma as Initial Presentation of Mycobacterium tuberculosis Infection].

Acta Med Port 2021 Mar 1;34(3):236. Epub 2021 Mar 1.

Serviço de Infecciologia. Hospital Garcia de Orta, EPE. Almada. Portugal.

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An Incidental Finding of a Double-Lumen Trachea.

Acta Med Port 2021 Mar 1;34(3):229-231. Epub 2021 Mar 1.

Department of Otolaryngology, Head and Neck Surgery. University of Medical Sciences. Poznań. Institute of Human Genetics. Polish Academy of Sciences. Poznań. Poland.

The aim of this case report is to present an incidental finding of a firm tracheal septum in a 61-year-old woman. The patient was admitted to the hospital with mild dyspnea and a preliminary diagnosis of a tracheal subglottic stenosis. During microlaryngoscopy, just below the subglottic stenosis, a firm, vertical symphysis (septum), forming a double-lumen trachea was found. Read More

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[Non-Necrotizing Acute Dermo-Hypodermal Infections: Erysipela and Infectious Cellulitis].

Acta Med Port 2021 Mar 1;34(3):217-228. Epub 2021 Mar 1.

Serviço de Dermatovenereologia. Centro Hospitalar e Universitário do Porto. Porto. Departamento de Dermatovenereologia. Instituto de Ciências Biomédicas Abel Salazar. Porto. Portugal.

Non-necrotizing acute dermo-hypodermal infections are infectious processes that include erysipela and infectious cellulitis, and are mainly caused by group A β-haemolytic streptococcus. The lower limbs are affected in more than 80% of cases and the risk factors are disruption of cutaneous barrier, lymphoedema and obesity. Diagnosis is clinical and in a typical setting we observe an acute inflammatory plaque with fever, lymphangitis, adenopathy and leucocytosis. Read More

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Benzodiazepine Use in Opioid Maintenance Treatment Programme: Risks and Clinical Outcomes.

Acta Med Port 2021 Mar 1;34(3):209-216. Epub 2021 Mar 1.

Drug Addiction Treatment Centre. Agualva-Cacém. Cacém. Portugal.

Introduction: The co-association of benzodiazepines and opioids is associated with an increased risk of overdose, death, and poorer psychosocial prognosis. The aim of this study is to characterize the prevalence, pattern of use, and primary clinical outcomes in benzodiazepines users in a public opioid maintenance treatment unit.

Material And Methods: We conducted a cross-sectional study involving 236 patients treated with opioid substitutes (methadone and buprenorphine). Read More

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Analysis of Medical Device Alerts Issued by the Portuguese Medicines Agency: Scoping the Purpose of New Regulatory Recommendations.

Acta Med Port 2021 Mar 1;34(3):201-208. Epub 2021 Mar 1.

Departamento de Sócio-Farmácia. Faculdade de Farmácia. Universidade de Lisboa. Lisboa. Portugal.

Introduction: Medical devices are healthcare technologies with a significantly growing market worldwide. This study aims to analyze medical device alerts issued by the Portuguese Medicines Agency, INFARMED, I.P. Read More

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[Early Detection of COVID-19 in Portugal: Use of Clinical Records].

Acta Med Port 2021 Mar 1;34(3):176-184. Epub 2021 Mar 1.

Departamento de Epidemiologia. Instituto Nacional de Saúde Doutor Ricardo Jorge. Lisboa. Portugal.

Introduction: Syndromic surveillance allows early detection of changes in the population's morbidity pattern. The aim of this study is to evaluate the usefulness of indicators related to access to healthcare services, in COVID-19 surveillance.

Material And Methods: A time series analysis was performed using the weekly incidence rate of COVID-19 in Mainland Portugal, between weeks 14/2020 (March 30 to April 5) and 25/2020 (June 15 to 21), and six indicators: 1) COVID-19 consultations in primary healthcare; 2) number of COVID-19 emergency department visits; 3) number of emergency department visits due to viral pneumonia; 4) number of hospitalizations due to viral pneumonia; 5) proportion of emergency department visits due to viral pneumonia; and 6) proportion of hospitalizations for viral pneumonia. Read More

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The State of Portuguese-American Health Disparities.

Acta Med Port 2021 Mar 1;34(3):171-172. Epub 2021 Mar 1.

Georgia State University. Atlanta. Georgia. United States.

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Periodontal status in long-term orthodontic retention patients up to 10 years after treatment - a cross-sectional study.

Acta Odontol Scand 2021 May 10:1-7. Epub 2021 May 10.

Section of Orthodontics, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.

Objective: To assess periodontal status in long-term orthodontic retention patients and investigate possible risk indicators.

Materials And Methods: Plaque index (PI), gingival index (GI), probing pocket depth (PPD), gingival recessions (GR) and calculus were recorded in 211 patients with or without fixed retainers.

Results: Periodontal parameters were within the limits of clinically healthy periodontium. Read More

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Effect of a sodium hypochlorite mouthwash on plaque and clinical parameters of periodontal disease.

Int J Dent Hyg 2021 May 10. Epub 2021 May 10.

Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands.

Objective: The present study aimed to establish the efficacy of sodium hypochlorite mouthwash (NaOCl-MW) compared with a control mouthwash on plaque and clinical parameters of periodontal disease.

Methods: MEDLINE-PubMed, Embase, and Cochrane-CENTRAL databases were searched for clinical trials on patients with gingivitis or periodontitis that assessed the effect of NaOCl-MW in comparison with a negative or positive control on plaque index (PI), gingival index (GI), and bleeding index (BI) scores and probing pocket depth (PPD). Data were extracted from the eligible studies. Read More

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