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    739 results match your criteria Acta Dermatovenerologica Croatica ADC [Journal]

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    Bullous Pemphigoid Masquerading as Erythema Annulare Centrifugum.
    Acta Dermatovenerol Croat 2017 Oct;25(3):255-256
    Sheng-Yiao Lin, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan;
    Dear Editor, Bullous pemphigoid (BP), a relatively common autoimmune blistering disease in the elderly, is characterized by large, tense bullae on urticarial, erythematous, or normal skin. However, atypical BP with polymorphic clinical presentations is rarely encountered, leading to misdiagnosis and delayed treatments (1). BP with lesions resembling erythema gyratum repens or figurate erythema has been regarded as a paraneoplastic phenomenon (1). Read More

    Heart Rate Variability in Patients with Psoriasis Treated with Etanercept Therapy.
    Acta Dermatovenerol Croat 2017 Oct;25(3):254
    Ertugrul Kurtoglu, MD, Ankara Cad. Ozalper Mah, 44100, Malatya, Turkey;
    In their article, Potenza et al. evaluated the influence of etanercept therapy on autonomic cardiovascular regulation in young patients with moderate-to-severe psoriasis without cardiovascular risk factors by measuring the time domain and frequency domain heart rate variability (HRV) parameters from 5-minute electrocardiogram (ECG) recordings (1). The authors used low frequency (LF), high frequency (HF) power, and LF/HF ratio as indices of frequency domain HRV and standard deviation of normal-to-normal intervals (SDNN); the mean root square of the sum of the squares of differences between consecutive R-R intervals (RMSSD) was used as the index of time domain HRV. Read More

    Nicolau's syndrome: A rare but preventable iatrogenic disease.
    Acta Dermatovenerol Croat 2017 Oct;25(3):251-253
    Assist. Prof. Tasleem Arif, MD, Postgraduate Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University, Aligarh, India;
    Dear Editor, Nicolau's syndrome, also called embolia cutis medicamentosa or livedoid dermatitis, is a rare injection site reaction characterized by immediate intense pain at the injection site followed by erythema and a hemorrhagic patch with a livedoid reticular pattern after injections of non-steroidal anti-inflammatory drugs (NSAIDS), antiepileptics, antibiotics, antihistaminics, corticosteroids, etc. (1). To the best of our knowledge, only one case of Nicolau's syndrome has been reported after the use of triamcinolone acetonide. Read More

    Folliculotropic Mycosis Fungoides Associated with Autoimmune Hepatitis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):248-250
    Prof. Romana Čeović, MD, PhD, University Hospital Center Zagreb, Department of Dermatology and Venereology School of Medicine, University of Zagreb, 10000 Zagreb, Šalata 4, Croatia;
    Dear Editor, the association between lymphomas and autoimmune manifestations, as well as the prevalence of the cases of coexistent lymphomas and autoimmune conditions, has not been completely established (1-3). Since cutaneous T-cell lymphoma (CTCL) cases are rare, any hypothesis can only be based on case reports or small case series. We present the case of a male patient with folliculotropic mycosis fungoides (FMF) and synchronous autoimmune hepatitis (AIH) with extremely high levels of cancer antigen 19-9 (CA 19-9). Read More

    Bevacizumab-associated Sudden Onset of Multiple Monomorphic Comedones on the Scalp Successfully Treated with 30% Salicylic Acid Peels.
    Acta Dermatovenerol Croat 2017 Oct;25(3):245-247
    Eftychia Platsidaki, MD, 5 Ionos Dragoumi Str, 16121 Athens, Greece;
    Bevacizumab is a humanized monoclonal antibody against vascular endothelial factor (VEGF) that targets tumor cell angiogenesis and proliferation. Although it is usually well tolerated, many side-effects have been reported. These include hypertension, bleeding, and thromboembolic events among others. Read More

    Long Lasting Allergic Patch Test Reactions: A Literature Review.
    Acta Dermatovenerol Croat 2017 Oct;25(3):238-244
    Giuseppe Mancuso, MD, Via Pescantini 33, 48022 Lugo Ravenna, Italy;
    Long-lasting allergic patch test reactions (LLAPTR) are those in which the clinical features of palpable erythema are still present at the site of a positive allergic patch test reaction 14 or more days after application of the allergen. LLAPTR have been described for a wide range of contact allergens, many of these included in the baseline patch test series. LLAPTR are far from uncommon; they occur in consecutive patients with positive patch tests to baseline allergens with frequency up to 17. Read More

    Aquagenic Urticaria: A Perplexing Physical Phenomenon.
    Acta Dermatovenerol Croat 2017 Oct;25(3):234-237
    Professor Robert A Schwartz MD, MPH, DSc (Hon), FRCP Edin Dermatology Rutgers New Jersey Medical School, 185 South Orange Avenue H-576, Newark, New Jersey 07103;
    Aquagenic urticaria (AQ) is a rare physical urticaria induced by contact with water. It may be distinctive clinically, evident as 1-2 mm folliculopapular urticaria, a pattern also characteristic of cholinergic urticaria. AQ has a truncal and upper extremity distribution within 20-30 minutes after contact with water, regardless of its temperature or source. Read More

    Bilateral Sacroiliitis Confirmed with Magnetic Resonance Imaging during Isotretinoin Treatment: Assessment of 11 Patients and a Review of the Literature.
    Acta Dermatovenerol Croat 2017 Oct;25(3):228-233
    Aslıhan Yonca Kocak, MD, Dumlupınar Üniversitesi Kütahya Evliya Çelebi Eğitim, ve Araştırma Hastanesi, 43100 Kütahya, Turkey;
    In recent years, several cases pointing at sacroiliitis due to isotretinoin treatment have been reported, but a causal association remains unproven. The aim of this study was to assess the characteristics of patients in whom bilateral sacroiliitis was detected while using isotretinoin treatment for acne and to review previous sacroiliitis cases treated with isotretinoin. In total, 11 patients who were diagnosed with sacroiliitis during isotretinoin treatment were identified, and patient characteristics were noted. Read More

    Real-Time Investigation of Skin Blood Flow Changes Induced by Topical Capsaicin.
    Acta Dermatovenerol Croat 2017 Oct;25(3):223-227
    Constantin Caruntu, MD, PhD, Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Ave. 050474 Bucharest, Romania;
    Capsaicin induces a localized inflammatory process known as neurogenic inflammation upon its topical administration on the skin, due to the release of various neuropeptides from the cutaneous sensory nerve endings. In this study, we investigated real-time skin blood flow changes that occur in neurogenic inflammation induced by topical capsaicin by means of in vivo reflectance confocal microscopy. 27 healthy subjects (15 women and 12 men, mean age ± Standard Deviation: 22. Read More

    The Impact of Changes in Psoriasis Area and Severity Index by Body Region on Quality of Life in Patients with Psoriasis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):215-222
    Professor Slavenka Janković, MD, PhD, Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Višegradska 26, 11000 Belgrade, Serbia;
    Psoriasis severity varies by body region, with each affected region having a different impact on patient quality of life (QoL). The aim of this study was to assess the impact of changes in the Psoriasis Area and Severity Index (PASI) scores by body region on QoL in patients with psoriasis after treatment. A total of 100 patients with psoriasis were recruited to the study. Read More

    Risk of Attention-Deficit/Hyperactivity Disorder in Children with Atopic Dermatitis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):210-214
    Amir Horev, MD, Pediatric dermatology service, Soroka University Medical Center, PO Box 151, Beer-Sheva, Israel;
    Atopic dermatitis (AD) is a common, chronic, inflammatory, pruritic skin disorder that affects up to 20% of the children in Western countries. Attention-Deficit/Hyperactivity disorder (ADHD) has been reported to be more frequent in children with AD. The purpose of this study was to explore the risk for ADHD in our population of patients with AD. Read More

    The Value of the BIOCHIP Mosaic-based Indirect Immunofluorescence Technique in the Diagnosis of Pemphigus and Bullous Pemphigoid in Turkish Patients.
    Acta Dermatovenerol Croat 2017 Oct;25(3):202-209
    Prof. Soner Uzun, MD, Department of Dermatology and Venerology Akdeniz University, School of Medicine, 07058 Antalya, Turkey;
    Autoimmune bullous diseases (ABD) are a rarely seen group of diseases, of which pemphigus and bullous pemphigoid (BP) are the major groups. Diagnosis is generally based on the combination of clinical features, histopathologic and immunofluorescence (IF) findings, and/or enzyme-linked immunosorbent assay (ELISA). Aims of the work were to determine the value of the innovative BIOCHIP mosaic-based indirect IF technique in the diagnosis of pemphigus and BP in Turkish patients. Read More

    Spectrum of Autoimmune Bullous Diseases in Northern Greece. A 4-year Retrospective Study and Review of the Literature.
    Acta Dermatovenerol Croat 2017 Oct;25(3):195-201
    Foteini Lamprou, MD, MSc, PhD candidate, 2nd University Department of Dermatology Papageorgiou General Hospital Aristotle University of Thessaloniki, Ring Road, Municipality of Pavlos Melas, Area of N. Efkarpia, 56403 Thessaloniki, Greece;
    Bullous Diseases Unit at the 2nd Department of Dermatology and Venereology, Aristotle University of Thessaloniki was founded with the aim to provide the optimal diagnostic approach and treatment of patients with autoimmune bullous diseases (AΙBD). We processed all AIBD files of patients diagnosed from 2011 to 2014 in order to record all epidemiological data and therapeutic manipulations during monitoring. 57 patients were diagnosed with intraepidermal and 62 with subepidermal bullous diseases. Read More

    HLA-E*0101/0103X is Associated with Susceptibility to Pemphigus Vulgaris: A Case-control Study.
    Acta Dermatovenerol Croat 2017 10;25(3):189-194
    Assoc. Prof. Savas Yayli, MD, Department of Dermatology Faculty of Medicine Karadeniz Technical University, TR 61080 Trabzon, Turkey;
    Pemphigus vulgaris (PV) is a life-threatening, autoimmune blistering disease of the skin and mucous membranes. The relationship between PV and human leukocyte antigen (HLA) has been studied in several reports. Previous reports have demonstrated that HLA-E polymorphisms may have a role in the susceptibility to various autoimmune diseases. Read More

    Epidemiology of Pemphigus in Turkey: One-year Prospective Study of 220 Cases.
    Acta Dermatovenerol Croat 2017 Oct;25(3):181-188
    Assoc. Prof. Savas Yayli, MD, Department of Dermatology Faculty of Medicine Karadeniz Technical University, 61080 Trabzon, Turkey;
    Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. Read More

    Xanthoma-like Skin Changes in an Elderly Woman with a Normal Lipid Profile.
    Acta Dermatovenerol Croat 2017 Jul;25(2):167-169
    Professor Joanna Maj, MD, PhD, Department and Clinic of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1, PL-50-368 Wrocław, Poland;
    Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Read More

    Topical Imiquimod is an Effective and Safe Drug for Molluscum Contagiosum in Children.
    Acta Dermatovenerol Croat 2017 Jul;25(2):164-166
    Efstathia Pasmatzi, MD, Department of Dermatology School of Medicine University of Patras, 26504 Rio-Patras, Greece;
    Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. Read More

    Diffuse Palmoplantar Keratoderma, Onychodystrophy, universal Hypotrichosis and Cysts.
    Acta Dermatovenerol Croat 2017 Jul;25(2):161-163
    Assist. Prof. Tasleem Arif, MD, MBSS (Dermatology, STD AND Leprosy) Postgraduate Department of Dermatology, STDs and Leprosy Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India;
    Dear Editor, Clouston syndrome, also called hidrotic ectodermal dysplasia (HED), is an autosomal dominant ectodermal dysplasia characterized by a clinical triad of onychodystrophy, generalized hypotrichosis, and palmoplantar keratoderma (1). Herein we report the case of a 24-year-old male with the distinctive clinical triad associated with multiple epidermoid cysts, which probably reflects the phenotype of Clouston syndrome. A 24-year-old male presented to our Department with diffuse thickening of the skin of his palms and soles since infancy. Read More

    Prognostic Predictors of Thin Melanoma in Clinico-Pathological Practice.
    Acta Dermatovenerol Croat 2017 Jul;25(2):159-160
    Luca Roncati MD, PhD , Department of Diagnostic and Clinical Medicine and of Public Health, Section of Pathology University of Modena and Reggio Emilia Policlinico Hospital, I-41124 Modena (MO), Italy;
    The latest reviews on thin melanoma (TM) continue to consider it a melanoma within 1 mm in thickness, but no consensus exists as to which patients with TM are at risk for lymph node metastases (1). Numerous studies have evaluated the impact of various predictors (Breslow thickness, Clark level, ulceration, regression, vascular invasion, mitotic activity, location, sex) for nodal disease in melanoma, but the conclusions have not been homogenous (2,3). For this reason, we read the paper by Homolak et al. Read More

    A 12-year-old Girl with Severe Plaque Psoriasis and Down Syndrome Treated Successfully with Etanercept.
    Acta Dermatovenerol Croat 2017 Jul;25(2):155-158
    Michał Adamczyk, MD, Department of Dermatology, Venerology and Paediatric Dermatology Medical University of Lublin, Radziwillowska 13, 20-080 Lublin, Poland;
    The association between Down syndrome and psoriasis is unclear. Immunological abnormalities that present in individuals with Down syndrome result in mild immune debilitation, thus the risk of infectious complications during immunosuppressive therapy might be higher in this group of patients. We present a case of 12-year-old girl with severe plaque psoriasis and Down syndrome, who was initially treated with cyclosporine with good response. Read More

    Kerion Celsi due to Microsporum canis with a Dermatophytid Reaction.
    Acta Dermatovenerol Croat 2017 Jul;25(2):151-154
    Biljana Gorgievska-Sukarovska, MD, Dermatology and Venereology Unit, Zabok General Hospital, Bračak 8, 49210 Zabok, Croatia;
    Microsporum (M.) canis is the most common fungus to cause tinea capitis in Europe, especially in the Mediterranean region and South and Central Europe. Fungal scalp infections caused by M. Read More

    Can Hematologic Parameters be an Indicator of Metabolic Disorders Accompanying Rosacea?
    Acta Dermatovenerol Croat 2017 Jul;25(2):145-150
    Asli Akin Belli, MD, Mugla Sitki Kocman University, Department of Dermatology, 48000, Mugla, Turkey;
    Recently, diverse hematologic parameters have been used as an indicator of the presence or severity of inflammatory and cardiovascular diseases. Our aim was to investigate the ratios of neutrophils to lymphocytes (NL), monocytes to high-density lipoprotein (HDL) cholesterol (MHC), and platelets to lymphocytes (PL) in patients with rosacea in comparison with the control group and determine whether there was a correlation between these ratios and metabolic disorders in patients with rosacea. We conducted a case-control study on 61 patients with rosacea and 60 healthy controls between January 2015 and January 2016 at the Dermatology Outpatient Clinic, Mugla, Turkey. Read More

    Association of Generalized Psoriasis and Mixed Glomerulonephritis in a 10-year-old Girl.
    Acta Dermatovenerol Croat 2017 Jul;25(2):142-144
    Prof. Danko Milošević, MD, PhD, Department of Pediatric Nephrology, Dialysis and Transplantation, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia;
    Generalized psoriasis and renal function disorder were previously described in sporadic adult cases, revealing a new entity - psoriatic nephropathy. So far there have been only two cases describing this association in children. We present and discuss a case of 10-year-old girl with the unique biopsy findings of double glomerulonephritis associated with the simultaneous onset of generalized psoriasis. Read More

    The Impact of Pyschological Stress on Acne.
    Acta Dermatovenerol Croat 2017 Jul;25(2):1133-141
    Anamaria Jović, MD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;
    Acne is one of the most common skin disorders. It is a multifactorial and complex disease, originating in the pilosebaceous follicle where a hereditary background, androgens, skin lipids, disorders of keratinization, inflammatory signaling, and regulatory neuropeptides seem to be mainly involved. Even though emotional stress has long been suspected to trigger or exacerbate acne, its influence on acne severity has been mostly underestimated until recently when studies have brought new data about the different mechanisms and possible factors involved in this interaction. Read More

    Sociodemographic, Sexual Behavior, and Microbiological Profiles of Men Attending Public Health Laboratories for Testing for Sexually Transmitted Diseases.
    Acta Dermatovenerol Croat 2017 Jul;25(2):125-132
    Assoc. Prof. Suncanica Ljubin-Sternak, MD, PhD¸, Clinical Microbiology Department, Dr. Andrija Štampar Teaching Institute of Public Health, Mirogojska 16, 10000 Zagreb, Croatia;
    In order to identify the groups at risk of sexually transmitted diseases (STDs), we assessed the sociodemographic profiles of men testing for STD, their sexual habits, and the results of microbiological analysis. During a three-year period, a total of 700 men older than 18 years of age completed the questionnaire regarding sociodemographic and sexual behavior. Urethral swabs were taken for microbiological analysis. Read More

    Translation and Validation of the Serbian Version of the Skindex-29 Instrument for Measuring Impact of Skin Disease on Quality of Life.
    Acta Dermatovenerol Croat 2017 Jul;25(2):120-127
    Prof. Slobodan M. Jankovic, MD, DSc, MSc, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica Street 69, 34000 Kragujevac, Serbia;
    The Skindex-29 instrument, which is intended for measuring the influence of skin diseases on quality of life, was developed and validated in several languages. However, a Serbian translation of the instrument is not available. The aim of this study was to translate the Skindex-29 from English to Serbian, to make necessary cultural adaptations, and to test its psychometric properties in a sample of outpatients with various skin diseases. Read More

    Mast Cell Disorders, Melanoma and Pancreatic Carcinoma: From a Clinical Observation to a Brief Review of the Literature.
    Acta Dermatovenerol Croat 2017 Jul;25(2):112-119
    Dario Didona, MD Istituto Dermopatico dell'Immacolata-IRCCS Via dei Monti di Creta 104, 00167 Rome Italy
    Mastocytosis can be associated with other clonal or non-clonal hematologic diseases as well as a variety of non-hematologic malignancies. A 75-year-old Caucasian male patient was referred to us with a 5-month history of neutrophilic leukocytosis and mild splenomegaly. He had developed a cutaneous melanoma sixteen years ago. Read More

    Comparison of Doxycycline and Benzathine Penicillin G for the Treatment of Early Syphilis.
    Acta Dermatovenerol Croat 2017 Jul;25(2):107-111
    Prof. Hongqing Tian, Prof. Furen Zhang, Shandong Provincial Institute of Dermatology and Venereology, 27397 Jingshi Road, Jinan, Shandong Province, 250022 China,
    Doxycycline is the preferred recommended second-line treatment for the treatment of early syphilis. Recent reports showed a declining efficacy trend of doxycycline in treatment of early syphilis. The aim of our study was to assess the serological response to the treatment for early syphilis with doxycycline compared with benzathine penicillin G and evaluate whether doxycycline is still an effective agent for the treatment of early syphilis. Read More

    Predictive Value of Intraoperative Sentinel Lymph Node Imprint Cytology Analysis for Metastasis in Patients with Melanoma.
    Acta Dermatovenerol Croat 2017 Jul;25(2):99-106
    Prof. Larisa Prpić Massari, MD, PhD Department of Dermatology, Clinical Hospital Center Rijeka, Krešimirova 42, 51000 Rijeka, Croatia;
    Since there are no standardized protocols regarding the detection of microscopic melanoma deposits in sentinel lymph nodes (SLN), the aim of this study was to present our experience with intraoperative cytological evaluation of SLN in patients with melanoma. The study included 475 SLN biopsies (SLNB) from 201 patients with primary cutaneous melanoma of intermediate thickness. Each lymph node was cut in half; touch imprint cytology (TIC) preparations of all cut surfaces were performed and stained according to a modified May-Grünwald-Giemsa method. Read More

    Development and Significance of the E-surveillance System for Contact Allergies in Slovenia.
    Acta Dermatovenerol Croat 2017 Jul;25(2):91-98
    Aleksandra Dugonik, MD, Department of Dermatology and Venereology, University Medical Centre, Ljubljanska street 2, 2000 Maribor, Slovenia;
    This paper describes the development and significance of online systems for the collection and analysis of medical data (patch test results) with a web application. Modern digital tools greatly aid in collecting, combining, and preserving the data in a way that is friendly, undemanding and time-efficient for the dermatologist. Creating a central database for the results of patch testing provides a better picture of contact sensitivity and characteristics of allergic contact dermatitis in Slovenia. Read More

    Thin Melanoma: A Generic Term Including Four Histological Subtypes of Cutaneous Melanoma.
    Acta Dermatovenerol Croat 2016 Dec;24(4):169-174
    Luca Roncati MD, PhD, Department of Diagnostic and Clinical Medicine and of Public Health Section of Pathology, University of Modena and Reggio Emilia, Policlinico Hospital, I-41124 Modena (MO), Italy;
    Today, the scientific community is focusing on the prognostic significance of different histological subtypes of thin melanoma (1). The current staging system for melanoma of the American Joint Committee on Cancer (AJCC) uses Breslow thickness as the primary attribute: melanomas with up to 1 mm thickness is defined as thin, because they present a good prognosis after surgical excision, with a 10-year survival rate of 85-90% in case of a tumor-free margin ≥1 cm (2). There is a significant interaction between mitotic rate and Breslow depth, so the predictive value of the mitotic rate on sentinel lymph node (SLN) positivity can be dependent on Breslow thickness (3). Read More

    Gestational Pityriasis Rosea: Suggestions for Approaching Affected Pregnant Women.
    Acta Dermatovenerol Croat 2016 Dec;24(4):312-313
    Efstathia Pasmatzi, MD, Department of Dermatology, School of Medicine, University of Patras, 26504 Rio-Patras, Greece;
    Dear Editor, Pityriasis rosea is a common, acute, and self-limiting dermatosis, which is associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7 (1). It predominantly affects individuals of both sexes in their second or third decade of life and is clinically characterized by the occurrence of an initial erythematosquamous plaque followed by the appearance of disseminated similar but smaller lesions one or two weeks later. Several patients develop systemic symptoms such as nausea, anorexia, malaise, headache, fever, arthralgia, and lymphadenopathy that may precede or accompany the eruption; the latter follows the cleavage lines of the trunk creating the configuration of a Christmas tree and spontaneously resolves within 4 to 8 weeks. Read More

    Vesicular Contact Reaction May Progress into Erythema Multiforme.
    Acta Dermatovenerol Croat 2016 Dec;24(4):307-309
    Prof. Magdalena Czarnecka-Operacz, MD, PhD, Department of Dermatology, 49 Przybyszewski Str., 60-355 Poznań, Poland.
    Dear Editor, Erythema multiforme is considered an acute skin condition, characterized by a self-limiting and sometimes recurrent course. It is regarded as a type IV hypersensitivity reaction associated with certain infections, medications, and other various triggers. Allergic contact dermatitis is in turn a delayed type of induced allergy as a result of cutaneous contact with a specific allergen to which the patient develops specific sensitivity. Read More

    Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome.
    Acta Dermatovenerol Croat 2016 Dec;24(4):305-306
    Hanna Przepiera-Będzak, MD, Department of Rheumatology and Internal Diseases, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
    The antiphospholipid antibody syndrome is defined by the presence of antiphospholipid antibodies in patients with recurrent venous or arterial thromboembolism (1). SAPHO syndrome is a rare disease, characterized by specific clinical manifestations of synovitis, acne pustulosis, hyperostosis, and osteitis. It is a disease that manifests with a combination of osseous and articular manifestations associated with skin lesions (2). Read More

    Boils at Frictional Locations in a Patient with Hidradenitis Suppurativa.
    Acta Dermatovenerol Croat 2016 Dec;24(4):303-304
    Jurr Boer, MD, PhD, Department of Dermatology Deventer Hospital, Nico Bolkesteinlaan 75, 7416 SE Deventer, The Netherlands;
    Dear Editor, Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease. The primary clinical presentation are painful inflamed nodules or boils of inverse areas, i.e. Read More

    Sonographic Detection of Subcutaneous Foreign Bodies in 3 Cases.
    Acta Dermatovenerol Croat 2016 Dec;24(4):299-302
    Tsuneo Watanabe, PhD, Division of Clinical Laboratory, Gifu University Hospital, 1-1, Yanagido, Gifu, 501-1194, Japan;
    Subcutaneous masses caused by foreign bodies are frequently encountered in daily practice. Although the majority of foreign bodies such as metals can be detected by radiography, substances such as vegetative materials or wood are difficult to detect. To our knowledge, only a few studies have described the sonographic characteristics of foreign bodies. Read More

    A Giant Basal Cell Carcinoma Misdiagnosed and Mistreated as a Chronic Venous Ulcer.
    Acta Dermatovenerol Croat 2016 Dec;24(4):296-298
    Dijana Celić, MD, PhD. Medikol Outpatient Department. Voćarska 106. 10 000 Zagreb, Croatia;
    Basal cell carcinoma (BCC) is the most common cutaneous malignancy. Giant BCCs are quite rare. They can cause extensive local invasion, disfigurement, and metastasis. Read More

    Dermoscopic Findings in Patients with Pigmented Purpuric Dermatoses.
    Acta Dermatovenerol Croat 2016 Dec;24(4):291-295
    Seray Külcü Çakmak, MD, Aykon Park sit. A Blok no:14 742.sokak, Yıldızevler Çankaya,
    Pigmented purpuric dermatoses (PPD) are a group of chronic and relapsing cutaneous disorders characterized by a distinct purpuric rash. The diagnosis is made with clinical and histopathological findings. Dermoscopy has rarely been used in the diagnosis of PPD. Read More

    Seroprevalence of Syphilis among Pregnant Women in the Varna Region (Bulgaria).
    Acta Dermatovenerol Croat 2016 Dec;24(4):288-290
    Tatina Todorova, PhD, Department of Preclinical and Clinical Sciences Faculty of Pharmacy, Medical University Varna, 3, Bregalnica Str. 9000 Varna, Bulgaria;
    Syphilis is a sexually transmitted disease with continuously rising rates among European countries. The vertical (mother to child) transmission is an important way of dissemination, often leading to stillbirth and permanent impairment of the newborn. We present a retrospective cross-sectional analysis of 2702 pregnant women tested for syphilis seropositivity. Read More

    Is There a Link between Human Herpesvirus Infection and Toll-like Receptors in the Pathogenesis of Pityriasis Rosea? A Case-control Study.
    Acta Dermatovenerol Croat 2016 Dec;24(4):282-287
    Corresponding author: Rania Abdel Hay, MD, 13th Abrag Othman, Kournish el Maadi, Cairo 11431, Egypt;
    Human herpesvirus (HHV) 6 and 7 are involved in the pathogenesis of pityriasis rosea (PR). Our aim was to evaluate the role of the innate immune response in PR through the detection of Toll-like receptors (TLR) 2, 3, 4, 7, 8, and 9 expression in the skin of affected patients and to detect the possibility of being induced by HHV-6 and/or HHV-7 viral coexistence in these patients. Twenty-four patients with PR and 24 healthy controls were included in this case-control study. Read More

    Distribution of Malassezia Species in Patients with Different Dermatological Disorders and Healthy Individuals.
    Acta Dermatovenerol Croat 2016 Dec;24(4):274-281
    Professor Asja Prohić, MD, PhD, Department of Dermatovenerology, University Clinical Center of Sarajevo, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina;
    There are differences with respect to the commonly isolated Malassezia species, not only between healthy individuals and the patients with various skin diseases, but also between different countries. We investigated the species composition of Malassezia microflora on the skin of patients with Malassezia-associated diseases and of healthy subjects (HS). Two hundred and fifty skin scrapings from patients with pityriasis versicolor (PV), seborrheic dermatitis (SD), atopic dermatitis (AD), psoriasis (PS), and healthy subjects (HS), fifty each, were inoculated into Sabouraud dextrose agar and into modified Dixon agar and identified using conventional culture-based methods. Read More

    Serum Cytokine Profiles in Infants with Atopic Dermatitis.
    Acta Dermatovenerol Croat 2016 Dec;24(4):268-273
    Asuman Gürkan, MD, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, Department of Dermatology, Telsizler, 06080, Ankara, Turkey;
    Atopic dermatitis (AD) in infancy is believed to have distinct features as compared to AD in other age groups, and little is known about cytokine production in infants with AD. We aimed to measure the serum cytokine levels of infants with atopic dermatitis and evaluate the association of new anti-inflammatory cytokines with the disease. Eighty-one infant patients with AD and 52 healthy controls were involved in this study. Read More

    Assessment of Cardiovascular Risk Factors in Patients with Psoriasis.
    Acta Dermatovenerol Croat 2016 Dec;24(4):261-267
    Szczerkowska-Dobosz Aneta, MD, PhD, 7th Debinki St., 80-211 Gdansk, Poland;
    Psoriasis is a chronic inflammatory skin disorder associated with increased cardiovascular risk. Aim of this work was to evaluate the association between psoriasis and chosen cardiovascular risk factors, echocardiographic parameters, and carotid intima-media thickness. A total of 50 patients with psoriasis and 50 controls were enrolled in the study. Read More

    Under the Surface of Subcutaneous Adipose Tissue Biology.
    Acta Dermatovenerol Croat 2016 Dec;24(4):250-260
    Vlatka Pandžić Jakšić, MD, PhD, Dubrava University Hospital, Av. G. Šuška 6, 10000 Zagreb, Croatia;
    The global obesity epidemic enhanced contemporary interest in adipose tissue biology. Two structurally and functionally distinct depots, subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT), are spread throughout the body. Their distribution was recognized to be a major determinant of metabolic risk. Read More

    The Role of Androgens and Estrogens in Hidradenitis Suppurativa - A Systematic Review.
    Acta Dermatovenerol Croat 2016 Dec;24(4):239-249
    Peter Theut Riis, MD, Department of Dermatology University Hospital Zealand, Køgevej 7-13, 4000 Roskilde, Denmark;
    Hidradenitis suppurativa (HS) is an inflammatory skin disease. Several observations imply that sex hormones may play a role in its pathogenesis. HS is more common in women, and the disease severity appears to vary in intensity according to the menstrual cycle. Read More

    Tinea on a Tattoo.
    Acta Dermatovenerol Croat 2016 Aug;24(3):223-4
    Marius Irimie, MD, 40, Zizinului Street, Bl. 31, Sc. C, Ap. 2, 500414, Brasov, Romania;
    In the last twenty years, the prevalence of individuals with tattoos in the general population has increased in Europe (1) as well as in Australia (2) and the United States of America (3). A series of complications such as acute inflammatory reactions, allergic contact dermatitis (4,5), photoinduced, lichenoid, and granulomatous reactions (6, 7), pseudolymphoma (8), pseudoepitheliomatous hyperplasia (9), skin infections (6), and skin cancers (10) may occur on tattoos. Infectious complications on tattoos include bacterial infections (pyoderma, leprosy, syphilis, cutaneous tuberculosis, mycobacteriosis) (11-14), viral infections (molluscum contagiosum, warts, herpes simplex, hepatitis B and C) (15-17), and fungal infections (sporotrichosis, dermatophytosis) (18,19). Read More

    Acupuncture as a Complementary Method of Traditional Psoriasis Treatment: Myth or Reality?
    Acta Dermatovenerol Croat 2016 Aug;24(3):221-2
    Assist. Prof. Darija Mahović, MD, PhD, School of Medicine Zagreb, University of Zagreb, Department of Neurology, University Hospital Center Zagreb, Kispaticeva 12, 1000 Zagreb, Croatia;
    Dear Editor, the practitioners of traditional Chinese medicine described psoriasis some 2000 years ago (1). Psoriasis vulgaris is a common, chronic inflammatory skin disease whose worldwide prevalence ranges from 0.1-3% (2,3). Read More

    Mycosis Fungoides Associated with Kaposi's Sarcoma, T-cell Rich B-cell Lymphoma, and T-cell Lymphoma with Angioimmunoblastic Features.
    Acta Dermatovenerol Croat 2016 Aug;24(3):218-20
    Ilan Goldberg, MD, Department of Dermatology, Tel Aviv Sourasky Medical Center, 6, Weizmann Street, Tel Aviv 64239, Israel;
    A patient with mycosis fungoides (MF), Kaposi's sarcoma, T-cell rich B-cell lymphoma, and T-cell lymphoma with angioimmunoblastic features is described. The appearance of multiple malignancies in this patient may have been caused by previous exposure to radiation in the Chernobyl accident and/or systemic chemotherapy for the initial T-cell rich B-cell lymphoma which he underwent. Read More

    PUVA-induced Bullous Pemphigoid in Psoriasis.
    Acta Dermatovenerol Croat 2016 Aug;24(3):214-7
    Irina Arsovska-Bezhoska, MD, Department of Dermatology, University of Ss. Cyril and Methodius, Naroden Front 35/13, Skopje, R. of Macedonia;
    The association between psoriasis vulgaris and bullous pemphigoid is due to the still unclear autoimmune process. The common disease site is the dermo-epidermal junction or basal membrane zone (BMZ), with specific alterations for both diseases. Photochemotherapy (PUVA) is one of the therapeutic modalities for psoriasis and can trigger production of autoantibodies against antigens in the BMZ in patients with subclinical bullous pemphigoid. Read More

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