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    757 results match your criteria Acta Dermatovenerologica Croatica ADC [Journal]

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    In Memoriam Assistant Professor Krešimir Kostović, MD, PhD 16 October 1969 - 15 October 2017.
    Acta Dermatovenerol Croat 2018 Apr;26(1):77-78
    On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Read More

    Activation of Herpes Simplex Infection after Tattoo.
    Acta Dermatovenerol Croat 2018 Apr;26(1):75-76
    Antigona Begolli Gerqari, MD, Dermatovenerology Clinic, University Clinical Center 10000 Pristina , Republic of Kosovo;
    Tattooing is a procedure where ink is applied to an area of the skin, mostly intraepidermally (1). This procedure is carried out mainly for aesthetic purposes. Lately, it has been used as a corrective medical procedure following amputation of mammilla. Read More

    Cutaneous Manifestations of Tuberous Sclerosis.
    Acta Dermatovenerol Croat 2018 Apr;26(1):73-74
    Vladimir Prelević, MD, Clinic for Nephrology Clinical Center of Montenegro, Ljubljanska bb 81101 Podgorica, Montenegro;
    Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). Read More

    Urticarial Lesions in a Pregnant Woman.
    Acta Dermatovenerol Croat 2018 Apr;26(1):71-72
    Sergio Santos-Alarcon, MD, Department of Dermatology, , Hospital Universitario Doctor Peset, Avinguda Gaspar Aguilar Nº 90, 4601 Valencia, Spain;
    Dear Editor, Gestational pemphigoid (GP) is a rare autoimmune bullous dermatosis in pregnancy. GP usually occurs during the second or third month of pregnancy. It clinically manifests as the development of either early-onset urticarial lesions or late-onset subepidermal blisters that may linger for weeks or even months. Read More

    Tatami Mats: A Source of Pitted Keratolysis in a Martial Arts Athlete?
    Acta Dermatovenerol Croat 2018 Apr;26(1):68-70
    Daniela Ledić Drvar, MD, PhD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;
    Dear Editor, Pitted keratolysis (PK), also known as keratosis plantaris sulcatum, is a non-inflammatory, bacterial, superficial cutaneous infection, characterized by many discrete superficial crateriform ''pits'' and erosions in the thickly keratinized skin of the weight-bearing regions of the soles of the feet (1). The disease often goes unnoticed by the patient, but when it is noticed it is because of the unbearable malodor and hyperhidrosis of the feet, which are socially unacceptable and cause great anxiety to many of the patients. PK occurs worldwide, with the incidence rates varying based on the environment and occupation. Read More

    Role of In Vivo Reflectance Confocal Microscopy in the Analysis of Melanocytic Lesions.
    Acta Dermatovenerol Croat 2018 Apr;26(1):64-67
    Elena-Daniela Serban, MD, Department of Medical Oncology, University of Bologna, 40138 Bologna; Italy.
    Worldwide melanoma incidence and mortality are increasing (1). Despite the ongoing research, advanced melanoma is still incurable; therefore, the most appropriate solution seems to be early detection combined with complete surgical excision (2). Since the diagnostic protocol of suspicious lesions includes a complete excision with safety margins (2), the problem of unnecessary scarring is significant. Read More

    Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
    Acta Dermatovenerol Croat 2018 Apr;26(1):61-63
    Benigno Monteagudo-Sánchez, MD, Hospital Arquitecto Marcide, Avenida Residencia SN , 15405 Ferrol (A Coruńa), A Coruńa, Spain;
    Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). Read More

    Reasons for not Using Condoms among Heterosexual Men in Belgrade, Serbia.
    Acta Dermatovenerol Croat 2018 Apr;26(1):58-60
    Milan Bjekić, MD, City Institute for Skin and Venereal Diseases , Džordža Vašingtona 17, 11000 Belgrade, Serbia;
    Dear Editor, Proper and consistent use of male condoms can be a highly effective method of preventing the transmission of sexually transmitted infections (STIs) and HIV (1), but this method relies on men's willingness and ability to use condoms. In the United States of America, about 20% overall and less than 50% of adults with multiple partners used a condom at last intercourse (2). In Serbia in 2013 (3), 50. Read More

    Lymphangioma Circumscriptum Post Radiotherapy for Penile Cancer Treated with CO₂ Laser.
    Acta Dermatovenerol Croat 2018 Apr;26(1):53-57
    Ancuta Proca Nicula, MD, PhD student, "Victor Babes" University of Medicine and Pharmacy, Dermatology Department, Eftimie Murgu No 2, 300041 Timisoara, Romania;
    Lymphangioma circumscriptum (LC) is a rare, benign condition, predominantly characterized by the malformation of lymphatic skin vessels. Its onset may be congenital or due to secondary causes such as radiotherapy, infections, or surgical procedures. We present the case of a 55-year-old patient with a pathologic history of squamous cell carcinoma of the penis followed by radical penectomy. Read More

    Poikilodermatous Mycosis Fungoides - Rare Entity, Different Treatment Modalities.
    Acta Dermatovenerol Croat 2018 Apr;26(1):48-52
    Prof. Romana Čeović, MD, PhD, Department of Dermatovenereology University Hospital Center Zagreb, University of Zagreb School of Medicine , Šalata 4, 10000 Zagreb, Croatia;
    Poikilodermatous mycosis fungoides (PMF) is a rare clinical variant of early-stage MF with peculiar histological features. Poikiloderma occurs in many different clinical conditions, which makes a diagnostic procedure more complicated. PMF belongs to a group of MF variants with low risk of disease progression. Read More

    Drug-induced Subacute Cutaneous Lupus Erythematosus Caused by a Topical Beta Blocker - Timolol.
    Acta Dermatovenerol Croat 2018 Apr;26(1):44-47
    Monika Bilewicz-Stebel, MD Department of Internal Medicine, Dermatology and Allergology, Curie-Skłodowskiej 10, 41-800 Zabrze, Poland, School of Public Health Medical University of Silesia in Katowice 40-027 Katowice, Poland;
    Drug-induced lupus erythematosus (DI-LE) is an autoimmune condition secondary to a recent pharmacological intervention. There are no established specific diagnostic criteria for DI-LE, and the disease is recognized based on the medical history of the patient. Typically, the onset is closely related to a recent drug exposure, and the disease terminates after discontinuation of the inducing factor. Read More

    Orthopedic and Cutaneous Reactions to Nickel after Total Hip Replacement.
    Acta Dermatovenerol Croat 2018 Apr;26(1):39-43
    Assist. Prof. Zrinjka Paštar, MD, PhD, Department of Health Studies , University of Zadar , Splitska 1 , 23000 Zadar, Croatia;
    Implant degradation products have shown signs of a cutaneous allergic response after implantation of a metal orthopedic replacement, loosening and failure of the joints as well as skin rashes, general fatigue, pain, and impaired wounds and bone healing. The prevalence of contact skin sensitivity in patients with a joint replacement device is higher than that in the general population. This delayed hypersensitivity to metallic orthopedic implants is more clearly defined and is a contributing factor to implant failure. Read More

    Treatment of Scabies and Pediculosis in Health Education Publications and Folk Medicine of Eastern Croatia - Slavonija, Baranja, and Western Srijem County.
    Acta Dermatovenerol Croat 2018 Apr;26(1):33-38
    Ivanka Muršić, MD, University Hospital Centre Osijek, Department of Dermatology and Venereology J. Huttlera 4, 31000 Osijek, Croatia;
    Scabies and pediculosis are common parasitic infestations of the skin and hair, manifesting with intense pruritus and effectively treated with modern medications. Because of the attached social stigma linking it with poverty and poor hygiene, patients will often attempt alternative folk-based remedies before confiding in their physicians. We conducted a comprehensive bibliographical study of historic folk literature and interviewed 70 individuals experienced in everyday application of folk medicine in order to categorize available remedies and provide a modern, scientific comment on their effectiveness and dangers. Read More

    Sexual Behaviors, Attitudes, and Knowledge about Sexually Transmitted Infections: A Cross-sectional Study in Romania.
    Acta Dermatovenerol Croat 2018 Apr;26(1):25-32
    Loredana Ungureanu, MD, 3-6 Clinicilor Street, Cluj-Napoca, Romania;
    Sexually transmitted infections (STIs) are serious public health problems. Little is known about sex knowledge, attitudes, and sexual behaviors among young adults in Romania; an effective preventive campaigns should be based on an appropriate understanding of these factors. The aim of the present study was to obtain data about sexual behavior, attitudes, and knowledge about STIs among university students aged 18-25 in Romania. Read More

    Diagnostic and Treatment Strategies of Dermatologists for Treating Morphea in Hungary.
    Acta Dermatovenerol Croat 2018 Apr;26(1):21-24
    Gabor Bali, MD, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41. 1085 Budapest, Hungary;
    Localized scleroderma is an uncommon disease, only infrequently encountered by dermatologists in private practices or even in larger academic centers. Because of its rarity, current treatment guidelines are mostly based on low-level clinical evidence and expert opinions. The aim of this study was to evaluate treatment strategies to treat localized scleroderma. Read More

    The Value of High-frequency 20 MHz Ultrasonography for Preoperative Measurement of Cutaneous Melanoma Thickness.
    Acta Dermatovenerol Croat 2018 Apr;26(1):15-20
    Andrea Kozárová, MD, Dermatovenereology Clinic University Hospital Martin, Kollárova 2, 036 01 Martin, Slovakia;
    High-frequency ultrasonography has become an important diagnostic tool in dermatovenerology. It is used for assessment of the cutaneous layers in diverse benign and malignant skin lesions and diseases. Herein we present the practical value of preoperative measurement of cutaneous melanoma thickness, the explanation of the possible reasons for different sonographic and histologic Breslow thickness, and the practical importance of high-frequency 20 MHz ultrasonography in preoperative measurements of cutaneous melanoma thickness. Read More

    Mycosis Fungoides and Vitamin D Status: Analyses of Serum 25-Hydroxyvitamin D Levels and Single Nucleotide Polymorphisms in the Vitamin D Receptor Gene.
    Acta Dermatovenerol Croat 2018 Apr;26(1):8-14
    Pinar Incel Uysal, MD, Talatpasa Bulvari, Ankara Numune Training and Research Hospital Dermatology Department, 06100, Altindag, Ankara , Turkey;
    Various types of cancer, including melanoma and non-melanoma skin cancer, are associated with vitamin D receptor (VDR) polymorphisms. However, few studies have addressed VDR polymorphisms in patients with mycosis fungoides (MF), and previous studies have reported conflicting results. Aim of this case-control study was to assess the correlation between VDR single nucleotide polymorphisms (SNPs) Cdx2, Fok1, Apa1, Bsm1, and Taq1 and MF. Read More

    Evaluation of Symptomatic Patients with Resistant Discharge.
    Acta Dermatovenerol Croat 2018 Apr;26(1):1-7
    Cemile Sonmez , PhD, Public Health General Directorate Ministry of Health, Adnan Saygun Street No: 55 , Sihhiye Ankara, Turkey;
    The aim of this study was to detect the presence of Chlamydia trachomatis, Neisseria (N.) gonorrhoeae, Mycoplasma (M.) hominis, M. Read More

    Bullous Pemphigoid Masquerading as Erythema Annulare Centrifugum.
    Acta Dermatovenerol Croat 2017 Oct;25(3):255-256
    Sheng-Yiao Lin, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan;
    Dear Editor, Bullous pemphigoid (BP), a relatively common autoimmune blistering disease in the elderly, is characterized by large, tense bullae on urticarial, erythematous, or normal skin. However, atypical BP with polymorphic clinical presentations is rarely encountered, leading to misdiagnosis and delayed treatments (1). BP with lesions resembling erythema gyratum repens or figurate erythema has been regarded as a paraneoplastic phenomenon (1). Read More

    Heart Rate Variability in Patients with Psoriasis Treated with Etanercept Therapy.
    Acta Dermatovenerol Croat 2017 Oct;25(3):254
    Ertugrul Kurtoglu, MD, Ankara Cad. Ozalper Mah, 44100, Malatya, Turkey;
    In their article, Potenza et al. evaluated the influence of etanercept therapy on autonomic cardiovascular regulation in young patients with moderate-to-severe psoriasis without cardiovascular risk factors by measuring the time domain and frequency domain heart rate variability (HRV) parameters from 5-minute electrocardiogram (ECG) recordings (1). The authors used low frequency (LF), high frequency (HF) power, and LF/HF ratio as indices of frequency domain HRV and standard deviation of normal-to-normal intervals (SDNN); the mean root square of the sum of the squares of differences between consecutive R-R intervals (RMSSD) was used as the index of time domain HRV. Read More

    Nicolau's syndrome: A rare but preventable iatrogenic disease.
    Acta Dermatovenerol Croat 2017 Oct;25(3):251-253
    Assist. Prof. Tasleem Arif, MD, Postgraduate Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University, Aligarh, India;
    Dear Editor, Nicolau's syndrome, also called embolia cutis medicamentosa or livedoid dermatitis, is a rare injection site reaction characterized by immediate intense pain at the injection site followed by erythema and a hemorrhagic patch with a livedoid reticular pattern after injections of non-steroidal anti-inflammatory drugs (NSAIDS), antiepileptics, antibiotics, antihistaminics, corticosteroids, etc. (1). To the best of our knowledge, only one case of Nicolau's syndrome has been reported after the use of triamcinolone acetonide. Read More

    Folliculotropic Mycosis Fungoides Associated with Autoimmune Hepatitis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):248-250
    Prof. Romana Čeović, MD, PhD, University Hospital Center Zagreb, Department of Dermatology and Venereology School of Medicine, University of Zagreb, 10000 Zagreb, Šalata 4, Croatia;
    Dear Editor, the association between lymphomas and autoimmune manifestations, as well as the prevalence of the cases of coexistent lymphomas and autoimmune conditions, has not been completely established (1-3). Since cutaneous T-cell lymphoma (CTCL) cases are rare, any hypothesis can only be based on case reports or small case series. We present the case of a male patient with folliculotropic mycosis fungoides (FMF) and synchronous autoimmune hepatitis (AIH) with extremely high levels of cancer antigen 19-9 (CA 19-9). Read More

    Bevacizumab-associated Sudden Onset of Multiple Monomorphic Comedones on the Scalp Successfully Treated with 30% Salicylic Acid Peels.
    Acta Dermatovenerol Croat 2017 Oct;25(3):245-247
    Eftychia Platsidaki, MD, 5 Ionos Dragoumi Str, 16121 Athens, Greece;
    Bevacizumab is a humanized monoclonal antibody against vascular endothelial factor (VEGF) that targets tumor cell angiogenesis and proliferation. Although it is usually well tolerated, many side-effects have been reported. These include hypertension, bleeding, and thromboembolic events among others. Read More

    Long Lasting Allergic Patch Test Reactions: A Literature Review.
    Acta Dermatovenerol Croat 2017 Oct;25(3):238-244
    Giuseppe Mancuso, MD, Via Pescantini 33, 48022 Lugo Ravenna, Italy;
    Long-lasting allergic patch test reactions (LLAPTR) are those in which the clinical features of palpable erythema are still present at the site of a positive allergic patch test reaction 14 or more days after application of the allergen. LLAPTR have been described for a wide range of contact allergens, many of these included in the baseline patch test series. LLAPTR are far from uncommon; they occur in consecutive patients with positive patch tests to baseline allergens with frequency up to 17. Read More

    Aquagenic Urticaria: A Perplexing Physical Phenomenon.
    Acta Dermatovenerol Croat 2017 Oct;25(3):234-237
    Professor Robert A Schwartz MD, MPH, DSc (Hon), FRCP Edin Dermatology Rutgers New Jersey Medical School, 185 South Orange Avenue H-576, Newark, New Jersey 07103;
    Aquagenic urticaria (AQ) is a rare physical urticaria induced by contact with water. It may be distinctive clinically, evident as 1-2 mm folliculopapular urticaria, a pattern also characteristic of cholinergic urticaria. AQ has a truncal and upper extremity distribution within 20-30 minutes after contact with water, regardless of its temperature or source. Read More

    Bilateral Sacroiliitis Confirmed with Magnetic Resonance Imaging during Isotretinoin Treatment: Assessment of 11 Patients and a Review of the Literature.
    Acta Dermatovenerol Croat 2017 Oct;25(3):228-233
    Aslıhan Yonca Kocak, MD, Dumlupınar Üniversitesi Kütahya Evliya Çelebi Eğitim, ve Araştırma Hastanesi, 43100 Kütahya, Turkey;
    In recent years, several cases pointing at sacroiliitis due to isotretinoin treatment have been reported, but a causal association remains unproven. The aim of this study was to assess the characteristics of patients in whom bilateral sacroiliitis was detected while using isotretinoin treatment for acne and to review previous sacroiliitis cases treated with isotretinoin. In total, 11 patients who were diagnosed with sacroiliitis during isotretinoin treatment were identified, and patient characteristics were noted. Read More

    Real-Time Investigation of Skin Blood Flow Changes Induced by Topical Capsaicin.
    Acta Dermatovenerol Croat 2017 Oct;25(3):223-227
    Constantin Caruntu, MD, PhD, Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Ave. 050474 Bucharest, Romania;
    Capsaicin induces a localized inflammatory process known as neurogenic inflammation upon its topical administration on the skin, due to the release of various neuropeptides from the cutaneous sensory nerve endings. In this study, we investigated real-time skin blood flow changes that occur in neurogenic inflammation induced by topical capsaicin by means of in vivo reflectance confocal microscopy. 27 healthy subjects (15 women and 12 men, mean age ± Standard Deviation: 22. Read More

    The Impact of Changes in Psoriasis Area and Severity Index by Body Region on Quality of Life in Patients with Psoriasis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):215-222
    Professor Slavenka Janković, MD, PhD, Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Višegradska 26, 11000 Belgrade, Serbia;
    Psoriasis severity varies by body region, with each affected region having a different impact on patient quality of life (QoL). The aim of this study was to assess the impact of changes in the Psoriasis Area and Severity Index (PASI) scores by body region on QoL in patients with psoriasis after treatment. A total of 100 patients with psoriasis were recruited to the study. Read More

    Risk of Attention-Deficit/Hyperactivity Disorder in Children with Atopic Dermatitis.
    Acta Dermatovenerol Croat 2017 Oct;25(3):210-214
    Amir Horev, MD, Pediatric dermatology service, Soroka University Medical Center, PO Box 151, Beer-Sheva, Israel;
    Atopic dermatitis (AD) is a common, chronic, inflammatory, pruritic skin disorder that affects up to 20% of the children in Western countries. Attention-Deficit/Hyperactivity disorder (ADHD) has been reported to be more frequent in children with AD. The purpose of this study was to explore the risk for ADHD in our population of patients with AD. Read More

    The Value of the BIOCHIP Mosaic-based Indirect Immunofluorescence Technique in the Diagnosis of Pemphigus and Bullous Pemphigoid in Turkish Patients.
    Acta Dermatovenerol Croat 2017 Oct;25(3):202-209
    Prof. Soner Uzun, MD, Department of Dermatology and Venerology Akdeniz University, School of Medicine, 07058 Antalya, Turkey;
    Autoimmune bullous diseases (ABD) are a rarely seen group of diseases, of which pemphigus and bullous pemphigoid (BP) are the major groups. Diagnosis is generally based on the combination of clinical features, histopathologic and immunofluorescence (IF) findings, and/or enzyme-linked immunosorbent assay (ELISA). Aims of the work were to determine the value of the innovative BIOCHIP mosaic-based indirect IF technique in the diagnosis of pemphigus and BP in Turkish patients. Read More

    Spectrum of Autoimmune Bullous Diseases in Northern Greece. A 4-year Retrospective Study and Review of the Literature.
    Acta Dermatovenerol Croat 2017 Oct;25(3):195-201
    Foteini Lamprou, MD, MSc, PhD candidate, 2nd University Department of Dermatology Papageorgiou General Hospital Aristotle University of Thessaloniki, Ring Road, Municipality of Pavlos Melas, Area of N. Efkarpia, 56403 Thessaloniki, Greece;
    Bullous Diseases Unit at the 2nd Department of Dermatology and Venereology, Aristotle University of Thessaloniki was founded with the aim to provide the optimal diagnostic approach and treatment of patients with autoimmune bullous diseases (AΙBD). We processed all AIBD files of patients diagnosed from 2011 to 2014 in order to record all epidemiological data and therapeutic manipulations during monitoring. 57 patients were diagnosed with intraepidermal and 62 with subepidermal bullous diseases. Read More

    HLA-E*0101/0103X is Associated with Susceptibility to Pemphigus Vulgaris: A Case-control Study.
    Acta Dermatovenerol Croat 2017 10;25(3):189-194
    Assoc. Prof. Savas Yayli, MD, Department of Dermatology Faculty of Medicine Karadeniz Technical University, TR 61080 Trabzon, Turkey;
    Pemphigus vulgaris (PV) is a life-threatening, autoimmune blistering disease of the skin and mucous membranes. The relationship between PV and human leukocyte antigen (HLA) has been studied in several reports. Previous reports have demonstrated that HLA-E polymorphisms may have a role in the susceptibility to various autoimmune diseases. Read More

    Epidemiology of Pemphigus in Turkey: One-year Prospective Study of 220 Cases.
    Acta Dermatovenerol Croat 2017 Oct;25(3):181-188
    Assoc. Prof. Savas Yayli, MD, Department of Dermatology Faculty of Medicine Karadeniz Technical University, 61080 Trabzon, Turkey;
    Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. Read More

    Xanthoma-like Skin Changes in an Elderly Woman with a Normal Lipid Profile.
    Acta Dermatovenerol Croat 2017 Jul;25(2):167-169
    Professor Joanna Maj, MD, PhD, Department and Clinic of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1, PL-50-368 Wrocław, Poland;
    Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Read More

    Topical Imiquimod is an Effective and Safe Drug for Molluscum Contagiosum in Children.
    Acta Dermatovenerol Croat 2017 Jul;25(2):164-166
    Efstathia Pasmatzi, MD, Department of Dermatology School of Medicine University of Patras, 26504 Rio-Patras, Greece;
    Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. Read More

    Diffuse Palmoplantar Keratoderma, Onychodystrophy, universal Hypotrichosis and Cysts.
    Acta Dermatovenerol Croat 2017 Jul;25(2):161-163
    Assist. Prof. Tasleem Arif, MD, MBSS (Dermatology, STD AND Leprosy) Postgraduate Department of Dermatology, STDs and Leprosy Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India;
    Dear Editor, Clouston syndrome, also called hidrotic ectodermal dysplasia (HED), is an autosomal dominant ectodermal dysplasia characterized by a clinical triad of onychodystrophy, generalized hypotrichosis, and palmoplantar keratoderma (1). Herein we report the case of a 24-year-old male with the distinctive clinical triad associated with multiple epidermoid cysts, which probably reflects the phenotype of Clouston syndrome. A 24-year-old male presented to our Department with diffuse thickening of the skin of his palms and soles since infancy. Read More

    Prognostic Predictors of Thin Melanoma in Clinico-Pathological Practice.
    Acta Dermatovenerol Croat 2017 Jul;25(2):159-160
    Luca Roncati MD, PhD , Department of Diagnostic and Clinical Medicine and of Public Health, Section of Pathology University of Modena and Reggio Emilia Policlinico Hospital, I-41124 Modena (MO), Italy;
    The latest reviews on thin melanoma (TM) continue to consider it a melanoma within 1 mm in thickness, but no consensus exists as to which patients with TM are at risk for lymph node metastases (1). Numerous studies have evaluated the impact of various predictors (Breslow thickness, Clark level, ulceration, regression, vascular invasion, mitotic activity, location, sex) for nodal disease in melanoma, but the conclusions have not been homogenous (2,3). For this reason, we read the paper by Homolak et al. Read More

    A 12-year-old Girl with Severe Plaque Psoriasis and Down Syndrome Treated Successfully with Etanercept.
    Acta Dermatovenerol Croat 2017 Jul;25(2):155-158
    Michał Adamczyk, MD, Department of Dermatology, Venerology and Paediatric Dermatology Medical University of Lublin, Radziwillowska 13, 20-080 Lublin, Poland;
    The association between Down syndrome and psoriasis is unclear. Immunological abnormalities that present in individuals with Down syndrome result in mild immune debilitation, thus the risk of infectious complications during immunosuppressive therapy might be higher in this group of patients. We present a case of 12-year-old girl with severe plaque psoriasis and Down syndrome, who was initially treated with cyclosporine with good response. Read More

    Kerion Celsi due to Microsporum canis with a Dermatophytid Reaction.
    Acta Dermatovenerol Croat 2017 Jul;25(2):151-154
    Biljana Gorgievska-Sukarovska, MD, Dermatology and Venereology Unit, Zabok General Hospital, Bračak 8, 49210 Zabok, Croatia;
    Microsporum (M.) canis is the most common fungus to cause tinea capitis in Europe, especially in the Mediterranean region and South and Central Europe. Fungal scalp infections caused by M. Read More

    Can Hematologic Parameters be an Indicator of Metabolic Disorders Accompanying Rosacea?
    Acta Dermatovenerol Croat 2017 Jul;25(2):145-150
    Asli Akin Belli, MD, Mugla Sitki Kocman University, Department of Dermatology, 48000, Mugla, Turkey;
    Recently, diverse hematologic parameters have been used as an indicator of the presence or severity of inflammatory and cardiovascular diseases. Our aim was to investigate the ratios of neutrophils to lymphocytes (NL), monocytes to high-density lipoprotein (HDL) cholesterol (MHC), and platelets to lymphocytes (PL) in patients with rosacea in comparison with the control group and determine whether there was a correlation between these ratios and metabolic disorders in patients with rosacea. We conducted a case-control study on 61 patients with rosacea and 60 healthy controls between January 2015 and January 2016 at the Dermatology Outpatient Clinic, Mugla, Turkey. Read More

    Association of Generalized Psoriasis and Mixed Glomerulonephritis in a 10-year-old Girl.
    Acta Dermatovenerol Croat 2017 Jul;25(2):142-144
    Prof. Danko Milošević, MD, PhD, Department of Pediatric Nephrology, Dialysis and Transplantation, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia;
    Generalized psoriasis and renal function disorder were previously described in sporadic adult cases, revealing a new entity - psoriatic nephropathy. So far there have been only two cases describing this association in children. We present and discuss a case of 10-year-old girl with the unique biopsy findings of double glomerulonephritis associated with the simultaneous onset of generalized psoriasis. Read More

    The Impact of Pyschological Stress on Acne.
    Acta Dermatovenerol Croat 2017 Jul;25(2):1133-141
    Anamaria Jović, MD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;
    Acne is one of the most common skin disorders. It is a multifactorial and complex disease, originating in the pilosebaceous follicle where a hereditary background, androgens, skin lipids, disorders of keratinization, inflammatory signaling, and regulatory neuropeptides seem to be mainly involved. Even though emotional stress has long been suspected to trigger or exacerbate acne, its influence on acne severity has been mostly underestimated until recently when studies have brought new data about the different mechanisms and possible factors involved in this interaction. Read More

    Sociodemographic, Sexual Behavior, and Microbiological Profiles of Men Attending Public Health Laboratories for Testing for Sexually Transmitted Diseases.
    Acta Dermatovenerol Croat 2017 Jul;25(2):125-132
    Assoc. Prof. Suncanica Ljubin-Sternak, MD, PhD¸, Clinical Microbiology Department, Dr. Andrija Štampar Teaching Institute of Public Health, Mirogojska 16, 10000 Zagreb, Croatia;
    In order to identify the groups at risk of sexually transmitted diseases (STDs), we assessed the sociodemographic profiles of men testing for STD, their sexual habits, and the results of microbiological analysis. During a three-year period, a total of 700 men older than 18 years of age completed the questionnaire regarding sociodemographic and sexual behavior. Urethral swabs were taken for microbiological analysis. Read More

    Translation and Validation of the Serbian Version of the Skindex-29 Instrument for Measuring Impact of Skin Disease on Quality of Life.
    Acta Dermatovenerol Croat 2017 Jul;25(2):120-127
    Prof. Slobodan M. Jankovic, MD, DSc, MSc, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica Street 69, 34000 Kragujevac, Serbia;
    The Skindex-29 instrument, which is intended for measuring the influence of skin diseases on quality of life, was developed and validated in several languages. However, a Serbian translation of the instrument is not available. The aim of this study was to translate the Skindex-29 from English to Serbian, to make necessary cultural adaptations, and to test its psychometric properties in a sample of outpatients with various skin diseases. Read More

    Mast Cell Disorders, Melanoma and Pancreatic Carcinoma: From a Clinical Observation to a Brief Review of the Literature.
    Acta Dermatovenerol Croat 2017 Jul;25(2):112-119
    Dario Didona, MD Istituto Dermopatico dell'Immacolata-IRCCS Via dei Monti di Creta 104, 00167 Rome Italy
    Mastocytosis can be associated with other clonal or non-clonal hematologic diseases as well as a variety of non-hematologic malignancies. A 75-year-old Caucasian male patient was referred to us with a 5-month history of neutrophilic leukocytosis and mild splenomegaly. He had developed a cutaneous melanoma sixteen years ago. Read More

    Comparison of Doxycycline and Benzathine Penicillin G for the Treatment of Early Syphilis.
    Acta Dermatovenerol Croat 2017 Jul;25(2):107-111
    Prof. Hongqing Tian, Prof. Furen Zhang, Shandong Provincial Institute of Dermatology and Venereology, 27397 Jingshi Road, Jinan, Shandong Province, 250022 China,
    Doxycycline is the preferred recommended second-line treatment for the treatment of early syphilis. Recent reports showed a declining efficacy trend of doxycycline in treatment of early syphilis. The aim of our study was to assess the serological response to the treatment for early syphilis with doxycycline compared with benzathine penicillin G and evaluate whether doxycycline is still an effective agent for the treatment of early syphilis. Read More

    Predictive Value of Intraoperative Sentinel Lymph Node Imprint Cytology Analysis for Metastasis in Patients with Melanoma.
    Acta Dermatovenerol Croat 2017 Jul;25(2):99-106
    Prof. Larisa Prpić Massari, MD, PhD Department of Dermatology, Clinical Hospital Center Rijeka, Krešimirova 42, 51000 Rijeka, Croatia;
    Since there are no standardized protocols regarding the detection of microscopic melanoma deposits in sentinel lymph nodes (SLN), the aim of this study was to present our experience with intraoperative cytological evaluation of SLN in patients with melanoma. The study included 475 SLN biopsies (SLNB) from 201 patients with primary cutaneous melanoma of intermediate thickness. Each lymph node was cut in half; touch imprint cytology (TIC) preparations of all cut surfaces were performed and stained according to a modified May-Grünwald-Giemsa method. Read More

    Development and Significance of the E-surveillance System for Contact Allergies in Slovenia.
    Acta Dermatovenerol Croat 2017 Jul;25(2):91-98
    Aleksandra Dugonik, MD, Department of Dermatology and Venereology, University Medical Centre, Ljubljanska street 2, 2000 Maribor, Slovenia;
    This paper describes the development and significance of online systems for the collection and analysis of medical data (patch test results) with a web application. Modern digital tools greatly aid in collecting, combining, and preserving the data in a way that is friendly, undemanding and time-efficient for the dermatologist. Creating a central database for the results of patch testing provides a better picture of contact sensitivity and characteristics of allergic contact dermatitis in Slovenia. Read More

    Thin Melanoma: A Generic Term Including Four Histological Subtypes of Cutaneous Melanoma.
    Acta Dermatovenerol Croat 2016 Dec;24(4):169-174
    Luca Roncati MD, PhD, Department of Diagnostic and Clinical Medicine and of Public Health Section of Pathology, University of Modena and Reggio Emilia, Policlinico Hospital, I-41124 Modena (MO), Italy;
    Today, the scientific community is focusing on the prognostic significance of different histological subtypes of thin melanoma (1). The current staging system for melanoma of the American Joint Committee on Cancer (AJCC) uses Breslow thickness as the primary attribute: melanomas with up to 1 mm thickness is defined as thin, because they present a good prognosis after surgical excision, with a 10-year survival rate of 85-90% in case of a tumor-free margin ≥1 cm (2). There is a significant interaction between mitotic rate and Breslow depth, so the predictive value of the mitotic rate on sentinel lymph node (SLN) positivity can be dependent on Breslow thickness (3). Read More

    Gestational Pityriasis Rosea: Suggestions for Approaching Affected Pregnant Women.
    Acta Dermatovenerol Croat 2016 Dec;24(4):312-313
    Efstathia Pasmatzi, MD, Department of Dermatology, School of Medicine, University of Patras, 26504 Rio-Patras, Greece;
    Dear Editor, Pityriasis rosea is a common, acute, and self-limiting dermatosis, which is associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7 (1). It predominantly affects individuals of both sexes in their second or third decade of life and is clinically characterized by the occurrence of an initial erythematosquamous plaque followed by the appearance of disseminated similar but smaller lesions one or two weeks later. Several patients develop systemic symptoms such as nausea, anorexia, malaise, headache, fever, arthralgia, and lymphadenopathy that may precede or accompany the eruption; the latter follows the cleavage lines of the trunk creating the configuration of a Christmas tree and spontaneously resolves within 4 to 8 weeks. Read More

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