890 results match your criteria Acta Dermatovenerologica Croatica ADC [Journal]


Desmoplastic Melanoma as a Diagnostic Pitfall.

Acta Dermatovenerol Croat 2020 Jul;28(1):49-50

Dear Editor, Desmoplastic melanoma (DM) is a rare histological subtype of melanoma, usually presenting as a slowly-growing, amelanotic, discoid, and/or firm lesion composed of spindle cells with abundant collagen (1). It is more common on sun-exposed areas, especially on head and neck in elderly patients (2). Regional lymph node involvement is reported to be less frequent than in other cutaneous melanomas (3). Read More

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Tattoo Pigment within Regional Lymph Nodes Mimicking Cutaneous Melanoma Metastasis.

Acta Dermatovenerol Croat 2020 Jul;28(1):47-48

Nikolina Jurišić, MD,

Dear Editor, The diagnosis of malignant melanoma accounts for 1-2% of all cancer diagnoses, around 4% of all malignant skin diseases, and 80% of all skin cancer deaths (1). The prognosis depends on several factors including tumor size, Clark level, Breslow thickness, location, ulceration, and presence of metastases. Detection of lymph node metastasis is initially accomplished by clinical examination and by operative evaluation for occult metastasis using sentinel lymph node biopsy (SLNB) when indicated (2). Read More

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Unusual Case of Granuloma Annulare Associated with Diabetes Mellitus.

Acta Dermatovenerol Croat 2020 Jul;28(1):45-46

Associate Professor Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb , Croatia;

Dear Editor, Granuloma annulare (GA) is an asymptomatic, chronic, and relatively common granulomatous skin condition which presents with annular papules usually slowly progressing into plaques on the extremities and the trunk. It usually presents with non-scaly, erythematous, annular plaques on the distal extremity (1,2). The pathogenesis of GA is still unknown, although a variety of possible factors contributing the disease have been reported, including drugs (3), insect bites, sun exposure, trauma, vaccinations, and viral infections (e. Read More

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Expression of p16 Protein in Cutaneous Basal Cell Carcinoma: Still far from Being Clearly Understood.

Authors:
Vladimir Bartoš

Acta Dermatovenerol Croat 2020 Jul;28(1):43-44

Vladimir Bartoš, MD, Faculty Hospital, Žilina, Slovakia;

Dear Editor, p16INK4a protein (p16) is an important tumor suppressor protein involved in the carcinogenesis of many human malignancies. I have read with interest an article by Donati et al. (1) in this journal, who investigated an expression of p16 and proliferation marker Ki-67 in cutaneous tumors. Read More

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Do Athletes Practicing Outdoors Know and Care Enough About the Importance of Photoprotection?

Acta Dermatovenerol Croat 2020 Jul;28(1):41-42

Prof. Marija Buljan, MD, PhD, Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Centre, Vinogradska 29, 10000 Zagreb, Croatia;

Athletes practicing and competing outdoors are exposed to considerable UV radiation and at an increased risk for the development of UV-related skin conditions, including skin cancer. Risk factors for skin cancer include genetics, immune status, and particularly UV radiation. Independent factors, such as phototype, family or personal history of melanoma, number of nevi, atypical nevi and solar lentigines, as well as sunburn history are also important risk indicators for skin cancer, especially melanoma (1-3). Read More

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Incomplete Schnitzler Syndrome.

Acta Dermatovenerol Croat 2020 Jul;28(1):38-40

Mattias A.S. Henning, MD, Department of Dermatology, Zealand University Hospital, Sygehusvej 5, 4000 Roskilde, Denmark;

Schnitzler syndrome (SS) is a rare autoinflammatory disease that presents with chronic urticaria and monoclonal immunoglobulin (Ig) M or G, accompanied by fever, abnormal bone remodeling, skin biopsy with a neutrophilic dermal infiltrate, leukocytosis, or elevated C-reactive protein. It is usually refractory to antihistamines and immunosuppression. We present a case report of clinical SS without monoclonal Ig with robust response to interleukin-1 inhibitor anakinra. Read More

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Topical Imiquimod for Management of Recurrent Lentigo Maligna Melanoma in Situ.

Acta Dermatovenerol Croat 2020 Jul;28(1):34-37

Professor Igor Bartenjev, MD, PhD, Department of Dermatovenerology, Medical faculty, University of Ljubljana, Pod kostanji 4, 1000 Ljubljana, Slovenia;

Topical imiquimod is a medication approved for the treatment of external genital and perianal warts, actinic keratosis, and superficial basal cell carcinoma. There have also been reports of its successful use in patients with lentigo maligna melanoma in situ. An 80-year-old female patient was diagnosed with lentigo maligna melanoma in situ which was then surgically removed. Read More

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Sight-threatening Complication of Cicatricial Ectropion in a Patient with Lamellar Ichthyosis - Case Report.

Acta Dermatovenerol Croat 2020 Jul;28(1):29-33

Natália Rybárová, MD, Oční klinika FN Brno, Jihlavská 20, 625 00 Brno, Czech Republic;

We report a case of lamellar ichthyosis and sight-threatening complications of cicatricial ectropion in an adult male patient which was surgically managed with tectonic penetrating keratoplasty. We present a case of autosomal-recessive lamellar ichthyosis in a 47-year-old man who was referred to our outpatient eye clinic for treatment of primary keratouveitis of the right eye with keratolysis and exudation in the anterior chamber. A diagnosis of cicatricial ectropion with serious lagophthalmos was established on examination. Read More

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Long-Term Efficacy of Treatment with Intravenous Immunoglobulin in Scleromyxedema.

Acta Dermatovenerol Croat 2020 Jul;28(1):24-28

Katarina Trčko, MD, PhD, Department of Dermatology and Venereal Diseases, University Medical Centre Maribor, Ljubljanska ulica 5, 2000 Maribo,r Slovenia;

Scleromyxedema or generalized lichen myxedematosus is a rare depositional disorder. Diagnostic criteria encompass a generalized papular and sclerodermoid eruption, monoclonal gammopathy (paraproteinemia), most often with G-lambda type immunoglobulin, a characteristic microscopic triad (mucin deposition, fibroblast proliferation, fibrosis), and absence of thyroid disease. Many internal manifestations of scleromyxedema have been described to date, leading to high mortality and morbidity. Read More

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Syphilis and Pharmaceutical Industry Marketing Between the Two World Wars in Croatia.

Acta Dermatovenerol Croat 2020 Jul;28(1):14-23

Martin Kuhar, MD, Division for the History of Medical Sciences, Croatian Academy of Sciences and Arts, Gundulićeva 24/III, 10000 Zagreb, Croatia;

Between the two World Wars, the pharmaceutical industry strengthened its influence within the Croatian medical community. Due to the scarcity of professional biomedical journals in the Croatian language, larger pharmaceutical companies started to publish free promotional journals, magazines, and booklets which quickly became popular. They thus succeeded in creating a broad network of opinion leaders by recruiting physicians as authors, primarily writing on their experiences with application of certain drugs. Read More

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Understanding the Relationship Between Smoking and Hidradenitis Suppurativa.

Acta Dermatovenerol Croat 2020 Jul;28(1):9-13

Joško Miše, MD, Department of Dermatology and Venereology, University Hospital Center Zagreb, School of Medicine, University of Zagreb, Šalata 4 , 10000 Zagreb, Croatia;

Hidradenitis suppurativa (HS) is a chronic skin disease affecting hair follicles in intertriginous areas, characterized by deep, recurrent, painful nodules and abscesses, fistulae, sinus tracts, and scarring. With a prevalence of 1-4%, HS is not an uncommon disease. Several risk factors have been linked with the development of HS, such as genetic predisposition, smoking, and obesity, leading to the hypothesis that HS develops as a result of environmental triggers in a genetically susceptible individual. Read More

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Risk Factors for HIV Transmission and HIV Testing Among Medical Students.

Acta Dermatovenerol Croat 2020 Jul;28(1):2-8

Associate Professor Pavel V. Chernyshov, MD, PhD, Department of Dermatology and Venereology, National Medical University, 13 Bulvar Shevchenko, 01601 Kiev, Ukraine;

Risky behavior in students is not infrequent. The prevalence of HIV in Ukraine is one of the highest in Europe. The aim of this study was to investigate risk factors of HIV transmission and prevalence of HIV testing in medical students from Ukraine. Read More

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What a challenging beginning of the year!

Acta Dermatovenerol Croat 2020 Jul;28(1)

At the beginning of the 28th year of the life of our Acta Dermatovenerologica Croatica Journal, we experienced so many challenges which are quite difficult to grasp of and which nobody could predicted in advance. It all began with some vague information from Wuhan about a new virus which was spreading quickly and which eventually led to a lock-down in our country as well. We had hoped that this would not have such a big impact on the life of the Journal, in fact we hoped that may some of our potential authors would have more time to finalize their previous research and send us their manuscripts. Read More

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Desmoplastic Trichoepithelioma: An Uncommon but Diagnostically Problematic Benign Adnexal Tumor.

Acta Dermatovenerol Croat 2019 Dec;27(4):282-284

Vladimír Bartoš, MD, PhD, MPH, Deapartment of Pathology Faculty Hospital in Žilina, Vojtecha Spanyola 43, 012 07 Žilina, Slovakia;

Dear Editor, I read an interesting recent article by Karimzadeh et al. (1) in an earlier issue of your journal, who provided a comprehensive review addressing a relatively rare benign tumor originating from the hair follicles - trichoepithelioma (TE). They rightly claimed that trichoepithelioma can be divided into the following 3 subgroups: a) multiple familiar TE, b) solitary non-hereditary TE, and c) desmoplastic trichoepithelioma (DTE). Read More

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December 2019

Human Orf: An Under-recognized Entity.

Acta Dermatovenerol Croat 2019 Dec;27(4):280-281

Luis Santiago, MD, Dermatology Department Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal;

Dear Editor, Orf, also called contagious ecthyma, contagious pustular dermatitis, sore mouth, or scabby mouth, is a highly contagious zoonotic disease which is caused by a double-stranded DNA virus, ORFV (Parapoxvirus genus of the family Poxviridae) (1). The infection is endemic to sheep and goats, and humans are infected either through direct transmission from active lesions on infected animals or through contact with fomites (2). Orf is an occupational hazard and the population at risk includes shepherds, butchers, farmers, wool shearers, and veterinarians (2,3). Read More

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December 2019

Dermoscopy of Mycobacterium marinum Skin infection: A Challenging Diagnosis.

Acta Dermatovenerol Croat 2019 Dec;27(4):278-279

Claudio Conforti, MD, Dermatology Clinic, Hospital Maggiore, Trieste, Italy;

Dear Editor, Mycobacterium (M.) marinum is a slow-growing atypical mycobacterium found mainly in saltwater environments. Infection occurs following inoculation of a skin lesion and manifests as a localized granuloma; in fact, the most common cause of infection with M. Read More

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December 2019

Topics and PRISMA Checklist Compliance for Meta-analyses in Dermatology: Journal Case Study.

Acta Dermatovenerol Croat 2019 Dec;27(4):275-277

Inés Poveda-Montoyo, MD, Department of Dermatology , Hospital General Universitario de Alicante, Pintor Baeza 11, Alicante 03010, Spain;

Meta-analyses are usually the final step of systematic reviews and provide robust scientific evidence (1,2). The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) Statement is a useful tool to improve the reporting of meta-analyses (3). There are few data available on the current topics and characteristics of meta-analyses in dermatology or on the clarity and comprehensiveness of the information they report (4-8). Read More

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December 2019

The Unna Boot: A Historical Dressing for Varicose Ulcers.

Acta Dermatovenerol Croat 2019 Dec;27(4):273-274

Assoc. Prof. Halil Tekiner, MD, PhD, Department of the History of Pharmacy and Ethics, Erciyes University School of Pharmacy , 38280 Kayseri, Turkey;

The German dermatologist Paul Gerson Unna (1850-1929) is a prominent figure in the history of medicine for pioneering modern dermatopathology and dermotherapy (Figure 1) (1). Aside from writing extensively on anatomy, histopathology, and treatment of skin diseases, he contributed to medicine in many other ways: he originated the idea of using coated pills to enhance local absorption in the intestine, introduced ammonium bituminosulfonate (ichthyol) and resorcinol into medicine, and described several skin conditions including seborrheic dermatitis. Moreover, in 1881 he established a private clinic in Hamburg, Germany, which became a leading expert center in the diagnosis and treatment of skin disorders, hosting postgraduate physicians from all over the world for training (2). Read More

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December 2019

Coexistence of Anogenital Psoriasis and Genital Warts - Is There an Optimal Treatment?

Acta Dermatovenerol Croat 2019 Dec;27(4):270-272

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology, Zagreb University Hospital Center, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;

The prevalence of psoriasis is 2% of the world's population (1). Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body. The prevalence of only anogenital involvement appears to be low, but involvement of the anogenital area together with other areas is found in up to 45% of patients with psoriasis (2). Read More

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December 2019

PHACES Syndrome with Intestinal Hemangiomatosis.

Acta Dermatovenerol Croat 2019 Dec;27(4):265-269

Professor Vjekoslav Krželj, MD, PhD, University of Split, School of Medicine , Department of Health Studies, Ruđera Boškovića 35, 21000 Split, Croatia;

We present a rare case of a neonate with PHACES syndrome (posterior fossa malformations, large facial hemangiomas, cerebral arterial anomalies, cardiovascular anomalies, eye anomalies and sternal clefting or supraumbilical raphe) and diffuse hemangiomatosis of the ileum, presenting with multiple intestinal perforations and peritonitis. The infant was successfully treated with propranolol and methylprednisolone as well as octreotide, tranexamic acid, and supportive therapy for massive intestinal bleeding. Read More

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December 2019

Gingival Papillomatosis as the Oral Sign of Cowden Syndrome: A Case Report.

Acta Dermatovenerol Croat 2019 Dec;27(4):260-264

Professor Marinka Mravak-Stipetić, DMD, MSc, PhD, School of Dental Medicine University of Zagreb, University Dental Clinic University Hospital Center Zagreb, Department of Oral Medicine, Gundulićeva 5, 10000 Zagreb, Croatia;

Cowden syndrome (CS) is a rare autosomal dominant, hereditary, multiorgan disease with higher risk for malignancies (breast, thyroid, endometrium). Mucocutaneous lesions occur in 90% of cases and are characterized by facial trichilemmomas, oral mucosal papillomas, and benign acral keratoses. We present the case of a 39-year-old female patient with the chief complaint of "white spots" on the upper and lower attached gingiva accompanied with skin changes on the face, hands, and soles. Read More

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December 2019
0.581 Impact Factor

Clinical Efficacy of Combination Therapy with Podophyllotoxin and Liquid Nitrogen Cryotherapy in the Treatment of Genital Warts in Men.

Acta Dermatovenerol Croat 2019 Dec;27(4):250-259

Prof. Zoran Golušin, MD, PhD, University of Novi Sad, Faculty of Medicine, Hajduk Veljkova 3, 21000 Novi Sad, Serbia;

High prevalence, peculiar etiopathogenesis, and ineffective therapies have contributed to the fact that genital warts are one of the most challenging issues in modern medicine. This prospective study was aimed at determining the clinical efficacy of combination therapy with 0.5% podophyllotoxin solution and liquid nitrogen cryotherapy in the local treatment of genital warts in men. Read More

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December 2019

Human Skin Microbiota in Various Phases of Atopic Dermatitis.

Acta Dermatovenerol Croat 2019 Dec;27(4):245-249

Assist. Prof. Elvina Murzina, MD, PhD, Department of Dermatovenereology Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine;

Skin microbiota can be used to assess the macroorganism's overall health. The quantitative and qualitative microbiota composition depends on the macroorganism's state, while microbiota bacteria can cause and maintain cutaneous inflammation, in turn worsening the macroorganism's state. This leads to placing additional focus on determination of skin microbiota when studying the pathogenesis of allergic dermatoses. Read More

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December 2019

Effectiveness and Pharmacokinetic evaluation of Geonistin® (Oxytetracyline and Nystatin) Vaginal Tablets for Unspecific and Mixed Vulvovaginal Infections (GENIE Study).

Acta Dermatovenerol Croat 2019 Dec;27(4):235-244

Mirjana Matrapazovski Kukuruzović, MD, PLIVA Croatia LTD, Prilaz baruna Filipovića 25, 10000 Zagreb, Croatia;

The GENIE study was performed to evaluate the effectiveness and systemic exposure to oxytetracycline in local treatment of unspecific and mixed vulvovaginal infections characterized by vaginal discharge with Geonistin® vaginal tablets (100 mg oxytetracycline and 100 000 IU nystatin). The total number of subjects enrolled was 189. The treatment had beneficial effects in 100% of the study population. Read More

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December 2019

Dermatomycosis in Cutaneous Tumors is a Predictor for Non-malignancy: A Cross-sectional Study.

Acta Dermatovenerol Croat 2019 Dec;27(4):231-12

Leo Čabrijan, MD, PhD, Department of Dermatology and Venereology Clinical Hospital Centre Rijeka, Krešimirova 42, 51000 Rijeka, Croatia;

The aim of this study was to evaluate the presence of spores and/or hyphae in benign cutaneous tumors (CT) and compare their presence in malignant cutaneous tumors. In this cross-sectional study we evaluated 328 CTs positive for spores and/or hyphae. The results show that the greatest number of involved CTs which contained spores and/or hyphae were found in compound nevi 181 (55. Read More

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December 2019

Clinicopathological Characteristics of BRAF V600E Mutated Melanomas in the Dalmatian Region of Croatia.

Acta Dermatovenerol Croat 2019 Dec;27(4):225-230

Joško Bezić, MD, MSc, Clinical Hospital Centre Split Institute of Pathology, Forensic Medicine and Cytology, Spinčićeva 1, 21 000 Spli,t Croatia;

A high proportion of cutaneous melanomas harbor activating mutations of the BRAF or NRAS genes, which are components of mitogen-activated protein kinase (MAPK) signal transduction pathway. The importance of BRAF V600E mutation in melanoma is not only related to the possibility of the administration of the targeted therapy, but also to the fact that BRAF V600E mutated melanomas have distinct clinicopathological features. We investigated the clinicopathological features of 80 primary skin melanomas with known BRAF V600E mutation status excised in the Dalmatian region of Croatia, with comparison of these features between the mutated and wild-type group. Read More

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December 2019

Intralesional Vitamin D3 in Recalcitrant Palmoplantar and Periungual Warts: A Prospective, Observational Study.

Acta Dermatovenerol Croat 2019 Dec;27(4):215-224

Assist. Prof. Mohammad Adil, MD, Department of Dermatology, Jawaharlal Nehru Medical College , Aligarh Muslim University, Aligarh, India;

Cutaneous warts are particularly difficult to treat with conventional treatment on sites such as the palms, soles, and periungual region. Immunotherapy boosts the host immune response and helps clear warts with less chance of recurrence. Vitamin D plays an important role in proliferation and differentiation of keratinocytes. Read More

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December 2019

Lymphomatoid Papulosis Type B in a Patient with Crohn's Disease Treated with TNF-Alpha Inhibitors Infliximab and Adalimumab.

Acta Dermatovenerol Croat 2019 Sep;27(3):202-204

Márta Medvecz, MD, PhD, Department of Dermatology, Venerology and Dermatooncology, Semmelweis University, Mária utca 41, 1085 Budapest, Hungary;

Dear Editor, Lymphomatoid papulosis (LP) is a chronic, recurrent, usually self-limited papulonecrotic or papulonodular skin disease, which belongs to the group of primary cutaneous CD30+ lymphoproliferative disorders (1). Three main histological subtypes of LP have been recognized: type A (histiocytic), type B (mycosis fungoides-like), and type C (anaplastic large cell lymphoma-like). Recently, new histologic LP variants classified as type D (CD8-positive, cytotoxic form) and type E (angioinvasive form) have also been described. Read More

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September 2019
7 Reads

Rowell Syndrome in Nigeria: Systemic Lupus Erythematosus Presenting as Recurrent Erythema Multiforme in a Young Woman.

Acta Dermatovenerol Croat 2019 Sep;27(3):200-201

Richard Akintayo, MD, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria;

Dear Editor, Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by diverse patterns of auto-antibody production with multi-organ affectation. Cutaneous involvement, either alone or in association with other systemic illnesses, is one of its most common manifestations (1). Dermatologic disorders like malar and discoid rashes are quite suggestive of SLE. Read More

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September 2019
2 Reads

Tridimensional Matryoshka Tattoo: An Important.

Acta Dermatovenerol Croat 2019 Sep;27(3):198-199

Antonella Tammaro, MD, PhD, NESMOS, Sant'Andrea Hospital, Dermatology Unit, Sapienza, University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy;

Dear Editor, Tattooing is a global and ancient practice that has endured until the present day. It was originally used to indicate religious beliefs, tribal affiliation, loyalty to a leader, or had a therapeutic function. Adverse reactions from tattooing are common, and cutaneous reactions to red pigment have been widely reported (1,2). Read More

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September 2019
2 Reads

Oral and Vulvar Lichen Sclerosus.

Acta Dermatovenerol Croat 2019 Sep;27(3):195-197

Ivana Škrinjar, MD, Department of Oral Medicine, University Hospital Center Zagreb, Gundulićeva 5, 10000 Zagreb, Croatia;

Lichen sclerosus (LS) is a chronic, inflammatory, mucocutaneous disorder of genital and extragenital skin (1). Simultaneous involvement of the oral mucosa is extremely rare, but it may be the only affected area (2). A 55-year-old woman was referred to the Department of Oral Medicine, School of Dental Medicine University of Zagreb due to whitish lesions on the right ventrolateral part of the tongue and buccal mucosa with desquamative gingivitis (Figure 1, a-c). Read More

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September 2019
3 Reads

Grover's Disease in a Kidney Transplant Recipient.

Acta Dermatovenerol Croat 2019 Sep;27(3):192-194

Professor Nikolina Bašić-Jukić, MD, PhD, Department of Nephrology, Arterial , Hypertension, Dialysis and Transplantation, University Hospital Centre Zagreb, Kišpaticeva 12, 10000 Zagreb, Croatia;

Dear Editor, It is not unusual for patients with renal insufficiency to develop skin pathologies. There are reports in the literature of increased incidence of calciphylaxis, pruritus, perforating dermatoses, and porphyria cutanea tarda in this patient population (1). Although it is quite rare, Grover's disease (GD) has been reported in several patients with renal insufficiency, but only once in a renal transplant recipient (2). Read More

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September 2019
5 Reads
0.581 Impact Factor

Furuncular Myiasis of the Lower Leg.

Acta Dermatovenerol Croat 2019 Sep;27(3):190-191

Ferdinand Toberer, MD, Department of Dermatology, Venerology and Allergology, University Medical Center, Ruprecht-Karls-University, Im Neuenheimer Feld, 69120 Heidelberg, Germany;

A 35-year-old Caucasian woman, otherwise healthy, presented with a four weeks history of painful, inflammatory nodules, each with a central opening on her right lower leg (Figure 1). Intermittently, a marked serosanguinous secretion was noted. The remaining skin and mucosa were not affected. Read More

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September 2019
3 Reads

Occupational Airborne Contact Dermatitis Caused by Omeprazole.

Acta Dermatovenerol Croat 2019 Sep;27(3):188-189

Ružica Jurakić Tončić, MD, Department of Dermatology and Venereology University Hospital Center Zagreb, School of Medicine University of Zagreb, Croatia, Šalata 4, 10000 Zagreb, Croatia;

Airborne contact dermatitis (ACD) is a frequent condition, and there has been increasing recognition of the occupational origin of airborne contact dermatitis. ACD caused by drugs is often occupation-related and occurs mainly in healthcare workers who use the drugs for therapeutic aims and employees of pharmaceutical industries involved in the production of the drugs (1). Omeprazole (OM) is a proton pump inhibitor from the benzimidazole group used for treatment of gastric acid-related disorders (2). Read More

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September 2019
3 Reads

Baclofen-Induced Dyshidrosiform Bullous Pemphigoid in a Paraplegic Patient Complicated by Methicillin-Resistant Staphylococcus aureus (MRSA) and Urinary Infection.

Acta Dermatovenerol Croat 2019 Sep;27(3):184-187

Professor Liborija Lugović Mihić, MD, PhD, Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Vinogradska cesta 29, 10 000 Zagreb, Croatia;

Bullous pemphigoid (BP) is an autoimmune disorder which is usually chronic, with blistering that predominantly affects the skin and occasionally the mucosa, and which includes several different types. One of them is a very rare dyshidrosiform type which is localized on the hands and feet with small or large blisters on the palmoplantar surfaces. BP resulting from a drug reaction is a relatively rare occurrence, and so far more than 50 different medications have been identified as triggers. Read More

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September 2019
1 Read

Eruptive Nevi on the Palms and Soles with no Association with an Underlying Disease or Medications.

Acta Dermatovenerol Croat 2019 Sep;27(3):180-183

Danica Tiodorović, MD, PhD, Clinic of Dermatovenerology, Clinical Center of Niš, Medical Faculty, University of Niš, Bulevar Nemanjića 48, 18 000 Niš, Serbia;

Eruptive melanocytic nevi are an unusual phenomenon characterized by sudden onset of multiple melanocytic nevi on previously unaffected skin. The majority of case reports have linked this condition with blistering skin disease or immunosuppression. There are only three reports of eruptive nevi developing on the palms and /or soles in healthy individuals. Read More

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September 2019
2 Reads

The Role of the Skin Barrier in Periorificial Dermatitis.

Acta Dermatovenerol Croat 2019 Sep;27(3):169-179

Professor Branka Marinović, MD, PhD, Department of Dermatology and Venereology, University Hospital Centre Zagreb, School of Medicine University of Zagreb, 10000 Zagreb, Croatia;

Periorificial dermatitis, mostly known as perioral dermatitis, is a benign inflammatory facial dermatosis which can be a severe burden and even disfiguring and psychologically disturbing. The disease still presents a challenge for physicians when it comes to etiology and appropriate therapy. Although a variety of extrinsic and intrinsic factors have been proposed as etiopathogenetic factors, none of these fully explain complex pathogenesis of the disease. Read More

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September 2019

Melanoma Development: Current Knowledge on Melanoma Pathogenesis.

Acta Dermatovenerol Croat 2019 Sep;27(3):163-168

Professor Liborija Lugović-Mihić, MD, PhD, Department of Dermatovenerology , Sestre milosrdnice University Hospital Center, Vinogradska cesta 29, 10 000 Zagreb, Croatia;

The pathogenic features of melanomas include growth and amplification of atypical melanocytes associated with several features (self-sufficiency of growth factors, insensitivity to growth inhibitors, evasion of cellular apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion, and metastasis). These melanoma pathogenic events can be triggered by activating oncogenes or inactivating tumor-suppressor genes by means of molecular mechanisms such as dotted mutations, deletions, and translocations or epigenetic mechanisms such as microRNA expression and promoter methylation. In melanomas, an analysis of the gene aberrations in the genome has led to the discovery of the complex interaction of signaling pathways. Read More

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September 2019

The Role of CD8+ T-Cells and their Cytokines in the Pathogenesis of Psoriasis.

Acta Dermatovenerol Croat 2019 Sep;27(3):159-162

Professor Larisa Prpić-Massari, MD, PhD, Department of Dermatovenerology , Clinical Hospital Center Rijeka, University of Rijeka, Krešimirova 42, 51000 Rijeka; Croatia.

The important role of CD8+ T-cells in the pathogenesis of psoriasis is well-determined. However, besides type 1 cytokines that were formerly known, it was recently found that these cells secrete type 17 and type 22 cytokines. The majority of IL-17A+CD8+ T-cells in the blood belong to a subset of innate T-cells named mucosa-associated invariant T-cells (MAIT). Read More

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September 2019
1 Read

Mycosis Fungoides: A 10-year Turkish Experience.

Acta Dermatovenerol Croat 2019 Sep;27(3):153-158

Leyla Baykal Selçuk, MD, Department of Dermatology Karadeniz Techinical University School of Medicine, Trabzon, 61080, Turkey;

Mycosis fungoides is the most common primary cutaneous T cell lymphoma, characterized by erythematous patches and plaque lesions with slow progression to cutaneous tumors or extracutaneous involvements in some patients. We aimed to evaluate the clinical characteristics, treatment responses, disease courses, and mortality rates of our MF cases. The data of 100 patients with MF were retrospectively examined from medical records in our clinic between January 2005 and January 2015. Read More

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September 2019
4 Reads

Dermoscopic Differentiation of Facial Lentigo Maligna from Pigmented Actinic Keratosis and Solar Lentigines.

Acta Dermatovenerol Croat 2019 Sep;27(3):146-152

Ozlem Ozbagcivan, MD, Dokuz Eylul University, Faculty of Medicine, Department of Dermatology, 35340 Inciralti, Izmir, Turkey;

The differential diagnosis of lentigo maligna (LM) from pigmented actinic keratosis (PAK) and solar lentigines (SL) remains a challenge for clinicians, especially in the early stages of LM when there are no distinctive dermoscopic features. Objective of this study was to evaluate the frequencies of selective dermoscopic criteria in LM, PAK, and SL and to find the specific combination of distinguishing dermoscopic criteria for LM. Dermoscopists blinded to histopathological diagnosis evaluated 42 LM, 107 PAK, and 16 SL for the presence of predefined dermoscopic criteria. Read More

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September 2019
5 Reads

Application of Indirect Immunofluorescence on the Diagnosis of Pemphigus.

Acta Dermatovenerol Croat 2019 Sep;27(3):142-145

Suying Feng, MD, Zhiliang Li, MD,

Pemphigus is an autoimmune bullous disease, and although several diagnostic methods are now in use indirect immunofluorescence (IIF) is still considered an important tool for diagnosing pemphigus because of its convenience, repeatability, and reduced pain for patients. The goal of the present study was to evaluate the diagnostic value of IIF on normal human skin (NS), monkey esophagus (ME), and salt-split skin (SS) for better diagnosis of pemphigus. Clinical data of 70 patients with pemphigus and 56 control were collected. Read More

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September 2019
2 Reads

Identification and Antifungal Activity Profile of Candida Species Isolated from Patients with Pemphigus Vulgaris with Oral Lesions.

Acta Dermatovenerol Croat 2019 Sep;27(3):137-141

Keyvan Pakshir, PhD, Department of Parasitology and Mycology,, Basic Sciences in Infectious Diseases Research Center School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran;

Pemphigus vulgaris is an autoimmune disease that mostly affects the mucosa and oral cavity. Candida species can invade the mucosal lesions of these patients and cause diseases. The aim of this study was to identify the fungal agents isolated from mucosal lesions and evaluate antifungal activity profile against the isolates. Read More

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September 2019

Hyperpigmented Mycosis Fungoides - A Rare Entity.

Acta Dermatovenerol Croat 2019 Jun;27(2):131-132

Jaka Radoš, MD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Dear Editor, A 67-year-old man of Kosovar-Albanian ethnic origin (skin phenotype IV) presented to our dermatology clinic with generalized hyperpigmented patches and plaques all over the body, so-called melanoerythroderma (Figure 1). The lesions, which first appeared nearly six years ago, developed gradually; they were diagnosed as mycosis fungoides (MF), and were subsequently treated only with topical corticosteroids. We performed further examinations upon admission to our department. Read More

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June 2019
3 Reads

Dermoscopic Features of a Digital Myxoid Cyst.

Acta Dermatovenerol Croat 2019 Jun;27(2):129-130

Prof. Abián Mosquera Fernández, MD, University of A Coruña - Department of Health Sciences, San Ramón s/n 15471 Ferrol (A Coruña), Spain;

Dear Editor, We report a case of a patient admitted to our Department presenting a typical digital myxoid cyst. A 54-year-old man was referred by his general practitioner to the Department of Dermatology at our hospital due to the presence of an asymptomatic lesion on the third right toe. Physical examination revealed a rounded, red-bluish lesion in the eponychium less than 0. Read More

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June 2019
4 Reads

Giant Lumbar Polypoid Tumor with Bullae on its Surface.

Acta Dermatovenerol Croat 2019 Jun;27(2):127-128

Dr. Jorge Ocampo-Candiani, Chair of the Dermatology Department, University Hospital "Dr. José E. González", Universidad Autónoma de Nuevo León, Mitras Centro, Avenida Gonzalitos y Madero S/N, 64460 Monterrey, Mexico;

Dear Editor, Acrochordons are common benign neoplasms found in everyday practice. We present a rare case of a giant and single acrochordon on the lumbar region with signs of ischemia. The correlation of clinical, dermatoscopic, and histopathological analyses may help the clinician differentiate this entity from other benign and malignant dermatoses. Read More

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June 2019
10 Reads

Rowell's Syndrome Triggered by Omeprazole.

Acta Dermatovenerol Croat 2019 Jun;27(2):124-126

Lyubomir Dourmishev MD, PhD, Department of Dermatology and Venereology, Medical University - Sofia, Bulgaria, 1st Georgi Sofiiski Blvd,. 1431 Sofia, Bulgaria.

Dear Editor, Rowell's syndrome is a rare disease, characterized by the appearance of erythema multiforme (EM)-like lesions in patients with lupus erythematosus. It was initially reported by Rowell (1) in 1963 and its existence as a separate clinical entity is currently under debate (2,3). A few cases may have been induced by drugs such as systemic antimycotics, antibiotics, anticonvulsants, and more recently proton pump inhibitors (PPIs). Read More

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June 2019
7 Reads
0.581 Impact Factor

Adalimumab - Safe and Effective Therapy for an Adolescent Patient with Severe Psoriasis and Immune Thrombocytopenia.

Acta Dermatovenerol Croat 2019 Jun;27(2):121-123

Mariusz Sikora, MD, PhD, Department of Dermatology Medical University of Warsaw, Koszykowa 82A 02-008, Warsaw Poland;

Psoriasis has been linked to several comorbidities, including metabolic syndrome, atopy, and celiac disease. However, the association between immune thrombocytopenia and psoriasis has rarely been described. We report the case of an adolescent with severe psoriasis and concomitant immune thrombocytopenia who obtained remission during treatment with adalimumab. Read More

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June 2019
2 Reads

Cutaneous Pseudolymphoma: A Case Report.

Acta Dermatovenerol Croat 2019 Jun;27(2):116-120

Professor Liborija Lugović Mihić, MD, PhD, Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Vinogradska c. 29, 10000 Zagreb, Croatia;

Pseudolymphoma is a benign, reversible, inflammatory, reactive, and polyclonal lymphocyte proliferation, which regresses spontaneously or heals after elimination of the causal factor. A female patient, aged 33, presented with a painful, erythematosus, radiant tumor formation on the skin in the temporal region. The patient had enlarged lymph nodes on the right side of the neck before the appearance of that tumor formation. Read More

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June 2019
15 Reads

The Dermoscopic Rainbow Pattern - A Review of the Literature.

Acta Dermatovenerol Croat 2019 Jun;27(2):111-115

Mihai Lupu, MD, Department of Dermatology, "Carol Davila", University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, 050474 Bucharest, Romania;

The "rainbow" pattern is a relatively new dermoscopic term that describes a bluish-reddish coloration together with various colors of the rainbow observable mainly through polarized light dermoscopy. Despite several theories, the rainbow pattern has not yet been clearly associated with any particular histological structure. This feature has been described in skin lesions with abundant vascularization such as Kaposi's sarcoma, basal cell carcinoma, scars, squamous cell carcinoma, melanoma, and others. Read More

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June 2019
3 Reads