928 results match your criteria Acta Dermatovenerologica Croatica[Journal]


A Case of Dominant Dystrophic Epidermolysis Bullosa with a G2043R Mutation in the Type VII Collagen Gene.

Acta Dermatovenerol Croat 2020 Dec;28(4):251-252

Sayaka Yamaguchi, MD, PhD, Department of Dermatology Graduate School and Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0125, Japan;

Dear Editor, Dystrophic epidermolysis bullosa (DEB) is a subepidermal bulla, characterized by severe itching, lichenoid or nodular prurigo-like lesions, skin erosion, scars, milia, and nail dystrophy, resulting from COL7A1 mutation. Herein, we report a case of dominant DEB with a G2043R mutation in COL7A1. A-25-year-old Japanese woman was referred to our clinic for recurrent intense pruritis and hypertrophic scars on the abdomen (Figure 1, a). Read More

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December 2020

A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.

Acta Dermatovenerol Croat 2020 Dec;28(4):249-250

Hisayoshi Imanishi, MD, PhD, Division of Dermatology, Daito Central Hospital, 2-1-11 Ono, Daito, Osaka 574-0042, Japan;

Dear Editor, Dapsone is a dual-function drug with antimicrobial and antiprotozoal effects and anti-inflammatory features (1). In dermatology, it is a first choice for conditions such as leprosy, IgA pemphigus, dermatitis herpetiformis, and linear IgA bullous dermatosis, or an adjunctive treatment for, e.g. Read More

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December 2020

Born in the Purple: An Exceptional Case of Cutis Marmorata Telangiectatica Congenita.

Acta Dermatovenerol Croat 2020 Dec;28(4):247-248

Department of Dermatology, University General Hospital of Patras, Rion, Greece, Greece;

A full-term, 2-day-old female neonate with a congenital non-tender reticular patch that did not disappear with local warming was referred to our department for consultation. The family history as well as the antenatal course and delivery were unremarkable. On examination, we evidenced a fixed, marbled, bluish to deep purple lesion with a fishnet appearance extending over the right side of her body, face, and scalp. Read More

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December 2020

Plexiform Neurofibroma Without Neurofibromatosis Type 1.

Acta Dermatovenerol Croat 2020 Dec;28(7):245-246

Professor Uwe Wollina, MD, Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Friedrichtstrasse 41, 01067 Dresden, Germany;

Dear Editor, Plexiform neurofibroma (PNF) is a particular subtype of benign nerve sheath tumors with a reticular growth pattern not respecting tissue borders and involving several nerve branches or fascicles. It is most commonly reported in patients with neurofibromatosis type-1 (NF-1) and represents in up to 30% of NF-1 patients (1,2). Other possible associations include schwannomatosis, multiple cutaneous schwannomas syndrome, and rarely neurofibromatosis type-2 (NF-2) (3). Read More

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December 2020

Unusual Clinical Presentation of Giant Extragenital Condyloma.

Acta Dermatovenerol Croat 2020 Dec;28(7):240-241

Andrija Jovic, MD, Clinical Center of Nis, Clinic of Dermatovenereology , Bulevar Zorana Djindjica 48, Nis, Serbia;

Dear editor, Condylomata accuminatum (CA) is a human papillomavirus (HPV) related sexually transmitted infection (STI), clinically characterized by solitary or even clustered dark red or pink lesions solely affecting the anogenital area (1). CA involving the extragenital, non-mucosal skin has been sporadically reported (2-4). Diagnosis of CA is usually straightforward when the lesions are located on the anogenital area. Read More

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December 2020

Multiple Primary Melanomas in a Young Patient.

Acta Dermatovenerol Croat 2020 Dec;28(7):238-239

Georgia Kyriakou, MD, MsC, cPhD., Department of Dermatology, University General Hospital of Patras, University General Hospital of Patras, Rion 265 04, Greece;

A 45-year-old HIV-negative Caucasian man with no reported past medical history was referred to our Department with a large (7 cm in diameter) oozing nodule on the occipital region of the scalp with spontaneous periodical bloody or purulent discharge. The lesion had appeared over a period of six months, had an irregular color, non-specific dermoscopic features, and resembled squamous cell carcinoma. The physical examination revealed three more atypical melanocytic lesions (on the abdomen, back, and buccal mucosa), and multiple swollen occipital, postauricular, as well as superficial and deep cervical lymph nodes. Read More

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December 2020

The Histogenetic Model of Melanoma in the Modern Era of Personalized Medicine.

Acta Dermatovenerol Croat 2020 Dec;28(7):236-237

Prof. Luca Roncati, MD, DMLS, PhD , Polyclinic Hospital, Largo del Pozzo 71 - 41124 , Modena (MO), Italy;

Malignant melanoma (M) can be defined, quite simply, as a malignant neoplasm derived from melanocytes; however, there is great histological and, consequently, clinical variability from case to case (1). In order to try to overcome this intrinsic difficulty, various classification systems have been proposed over the years; as part of this effort, the World Health Organization (WHO) introduced its famous classification about half a century ago (2). Currently, the International Classification of Diseases for Oncology (ICD-O), provided by the WHO International Agency for Research on Cancer (IARC), distinguishes the in situ forms from invasive ones, recognizing four main morphological subtypes: nodular M, superficial spreading M, lentigo maligna M, and acral lentiginous M (3). Read More

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December 2020

Dermoscopic Features of Giant Molluscum Contagiosum in a Patient with Acquired Immunodeficiency Syndrome.

Acta Dermatovenerol Croat 2020 Dec;28(7):233-235

Martyna Sławińska MD, PhD, Department of Dermatology, Venereology and Allergology Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214 Gdańsk;

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to typical molluscum contagiosum, dermoscopic features of giant lesions have been poorly described, and none of the reports included multiple giant lesions in an immunocompromised patient. We present a patient with acquired immunodeficiency syndrome diagnosed with multiple giant molluscum contagiosum along with the dermoscopic features of this entity. Read More

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December 2020

A Recurrent Case of Targetoid Hemosiderotic Hemangioma: A Case Report and a Comprehensive Review of the Literature.

Acta Dermatovenerol Croat 2020 Dec;28(7):228-232

Roxana Chiorean, MD, Frankfurter Str 90, PLZ 63110, Rodgau, Germany;

Targetoid hemosiderotic hemangioma is an acquired vascular malformation of unknown origin. We report the case of a 31-year-old man with a recurrent and spontaneous regressive targetoid hemosiderotic hemangioma. Diagnosis relied on clinical and histological findings. Read More

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December 2020

Tophaceous Gout - When the Skin Comes First.

Acta Dermatovenerol Croat 2020 Dec;28(7):223-227

Professor Carmen Salavastru, MD, PhD, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania;

Gout represents a metabolic disorder with systemic echo, in which needle-like crystals of monosodium urate are deposited in various tissular structures. Crystals accumulation in the connective tissue (tophi) represents the late, chronic stage of this disease, usually emerging after an average of 10 years after disease onset. Herein we report three cases of patients aged 70, 33, and 53 who presented with painful subcutaneous nodules located on various body areas. Read More

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December 2020

Were All Compulsorily Committed Women Prostitutes? Closed Venereology Wards in East Germany.

Acta Dermatovenerol Croat 2020 Dec;28(7):215-222

Assistant Professor Maximilian Schochow, MD , Ulm University, Institute of the History, Philosophy and Ethics of Medicine, Parkstraße 11, D-89073 Ulm, Germany;

Were the women that were compulsorily committed to closed venereology wards in the Soviet Occupation Zone (SOZ) and German Democratic Republic (GDR) prostitutes and sexually promiscuous individuals? 1,241 patient records of the closed venereology ward in Leipzig-Thonberg were researched in the Leipzig Municipal Archive and evaluated using the historical-critical method. Two periods were investigated: June 1946 to February 1961 (the period of validity of the Orders of the Soviet Military Administration in Germany - SMAG) and March 1961 to August 1990 (period of validity of the GDR regulation).During the two periods of investigation, 3% of the women compulsorily committed to the closed venereology ward Leipzig-Thonberg were prostitutes. Read More

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December 2020

Mohs Surgery Outside Usual Indications: A Review.

Acta Dermatovenerol Croat 2020 Dec;28(7):210-214

Pedro Rodríguez-Jiménez, MD, Dermatology Department, Hospital Universitario de la Princesa, Madrid, Calle Diego de Leon 62, 28006 Madrid, Spain;

The body of literature supporting the use of Mohs micrographic surgery (MMS) in tumors outside the main indications (basal cell carcinoma, squamous cell carcinoma, dermatofibrosacroma protuberans, lentigo maligna) is constantly growing, but it is still based on case reports, case series, or at best institutional case series that focus on a single malignancy. Our aim in this review was to assess use of MMS in an array of rare tumors outside the usual indications. A review was performed using the MEDLINE database and the search engine ClinicalKey®. Read More

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December 2020

Candida Distribution in Onychomycosis and in vitro Susceptibility to Antifungal Agents.

Acta Dermatovenerol Croat 2020 Dec;28(7):204-209

Algimantas Paškevičius, PhD, Laboratory of Biodeterioration Research, Nature Research Centre, Vilnius, Lithuania;

The aim of this study was to determine distribution of the Candida (C.) species in onychomycosis and analyses in vitro susceptibility to fluconazole and itraconazole. In recent years, cases of onychomycosis in Lithuania caused by Candida have increased significantly. Read More

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December 2020

Contact Sensitivity in Patients with Atopic Dermatitis.

Acta Dermatovenerol Croat 2020 Dec;28(7):197-203

Professor Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology , University Hospital Center Zagreb , University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;

Atopic dermatitis (AD) is a common chronic and relapsing, non-contagious inflammatory skin disorder, characterized by skin barrier impairment and baseline immune irregularities. The literature on the relationship between AD and cutaneous delayed-type hypersensitivity is inconclusive. There is an ongoing debate whether contact sensibility (CS) is found more or less often among patients with AD. Read More

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December 2020

Eosinophilic Fasciitis - Clinical Features and Therapeutic Management.

Acta Dermatovenerol Croat 2020 Dec;28(3):190-192

Monika Bilewicz-Stebel, MD, Department of Internal Medicine, Dermatology and Allergology, Curie-Skłodowskiej 10, 41-800 Zabrze, Poland;

Eosinophilic fasciitis is a rare disease from the group of scleroderma-like connective tissue diseases with unclear etiopathogenesis. It may be occasionally accompanied with other eosinophilic or autoimmune dysfunctions (1,2). Lack of international diagnostic criteria and treatment consensus may lead to diagnostic and therapeutic difficulties. Read More

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December 2020

Frontal Fibrosing Alopecia: Successfully Treated with Methotrexate or Just the Natural Disease Progression?

Acta Dermatovenerol Croat 2020 Dec;28(3):188-189

Matheo Augusto Morandi Stumpf, MD, Av. Carlos Cavalcanti, 4748, Medicine Department, Uvaranas, CEP: 84030-900, Ponta Grossa, Brazil;

A 53 year-old-woman presented to our dermatology clinic with a 3-year history of hair loss and pruritus of the anterior scalp. She denied drug use, comorbidities, and other systemic symptoms. Physical examination revealed a band-like recession of the frontotemporal hairline with loss of the eyebrows and perifollicular erythema. Read More

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December 2020

Sexually Transmitted Infections in a Cohort of 15,921 Refugees (1926-1940) in the Region of Imathia, Northern Greece.

Acta Dermatovenerol Croat 2020 Dec;28(3):180-187

Spyros N. Michaleas, BA, MA, PhD candidate, Department of History of Medicine and Medical Deontology, Medical School, University of Crete, Heraklion, Greece;

This historical epidemiological study evaluates sexually transmitted infections (STIs) among Greek refugees during the Interwar period in the region of Imathia, Central Macedonia, Greece, as a part of the effort against sexually transmitted infections in Greece (1910-1940). We examined the archives of the Refugee Hospital of Veroia - the capital of the regional unit of Imathia (March 5, 1926 to October 27, 1940). This is a report of previously unpublished primary material comprising a cohort of 15,921 cases, among whom 41 patients were hospitalized on account of syphilis and 19 on account of gonococcal infection. Read More

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December 2020

On- and Off-Label Uses of Apremilast in Dermatology.

Acta Dermatovenerol Croat 2020 Dec;28(3):171-179

Kerasia-Maria Plachouri, MD University General Hospital of Patras,, Rio 265 04 Patras, Greece;

Apremilast is an oral small-molecule phosphodiesterase 4 inhibitor with a multilevel immunomodulating mechanism of action. It has received approval in many countries for the use in moderate-to-severe plaque psoriasis and active psoriatic arthritis in adults. Herein, we review the literature concerning the use of apremilast in dermatology, with a focus on both the on- and the off-label uses of this medication in dermatologic conditions. Read More

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December 2020

What is the Best Way to Treat Patients with Raynaud's Phenomenon and a Tendency towards Hypotension?

Acta Dermatovenerol Croat 2020 Dec;28(3):166-170

Hanna H. Drobek. MD, Medical University of Silesia in Katowice, Katowice, Poland;

Episodes of excessive vasospasm are common in patients with Raynaud's phenomenon (RP). Pharmacological treatment may often result in side-effects such as hypotension, leading to discontinuation of treatment. Review of therapeutic interventions with regard to tendency towards hypotension was done in medical databases including PubMed, Scopus, and Medline to summarize the current state of the knowledge. Read More

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December 2020

Noninvasive Imaging Techniques for the Diagnosis of Nonmelanoma Skin Cancers.

Acta Dermatovenerol Croat 2020 Dec;28(3):157-165

Mirela Krišto, MD, Department of Dermatology and Venereology Sestre milosrdnice University Hospital Center , Vinogradska cesta 29, 10 000 Zagreb, Croatia;

Nonmelanoma skin cancers (NMSC), basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (cSCC) are the most common neoplasms worldwide. Their incidence has been continually rising. This is due to several risk factors such as chronic sun exposure, longer life expectancy, sun-damaged skin, genetic predisposition, and immunosuppression. Read More

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December 2020

Concomitant Hidradenitis Suppurativa and Eruptive Xanthomas Presenting with Phimosis - The Importance of Timely Diagnosis.

Acta Dermatovenerol Croat 2020 Dec;28(3):154-156

Rune Kjærsgaard Andersen, MD, Dept. of Dermatology, University Hospital Zealand, Sygehusvej 10, 4000 Roskilde, Denmark;

A 49-year-old man diagnosed with metabolic syndrome (MetS) was referred to us for treatment of xanthoma elements. Physical examination revealed widespread confluent yellow firm papules on his fingers, toes, arms, legs, and back. The diagnosis of eruptive xanthoma (EX) was clinically confirmed. Read More

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December 2020

Influence of Non-pharmacological Treatment on Pain, Morning Stiffness, Fatigue, and Physical Function in Patients with Psoriatic Arthritis.

Acta Dermatovenerol Croat 2020 Dec;28(3):148-153

Stjepan Čota, MD, Children's Hospital Zagreb, Klaićeva 16, 10000 Zagreb, Croatia;

Naphthalanotherapy (NT) is a therapeutic procedure that uses mineral oil obtained from petroleum. The aim of this study was to investigate the influence of the duration of NT combined with an individually adjusted rehabilitation program (IARP) on pain, morning stiffness (MS), fatigue, and physical function in patients with psoriatic arthritis (PsA). A total of 29 consecutive patients with PsA were divided into two groups. Read More

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December 2020

How to Cope with Psoriasis: Data from Patient Tests and Surveys.

Acta Dermatovenerol Croat 2020 Dec;28(3):141-147

Prof. Liborija Lugović-Mihić, MD, PhD, Department of Dermatovenereology Sestre milosrdnice University Hospital Center, 10000 Zagreb, Croatia;

There are a limited number of studies that have addressed coping strategies in patients with psoriasis, so the aim of this study was to examine how patients with psoriasis cope with their illness. We included 122 participants in the study: 56 patients with psoriasis vulgaris and 66 healthy subjects. They filled out the Recent Life Changes Questionnaire (RLCQ), blinded to their stress and clinical status, and the Brief COPE questionnaire with 28 questions measuring 14 coping strategies that are either adaptive or maladaptive. Read More

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December 2020

The Skin as a Mirror of Internal Disease: Comorbidities and Epidemiology of Acne Vulgaris and Adult Female Acne - A Cross-sectional Study and Current State of Knowledge.

Acta Dermatovenerol Croat 2020 Dec;28(3):133-140

Katarzyna P. Kaleta, MD, Department of Dermatology Jagiellonian University Medical College, 8 Skawinska St, 30-066 Krakow, Poland;

Acne vulgaris is a common skin condition affecting an increasing number of adults and might be a clue to identifying systemic disease. Objective of this study is assessment of the demographic and clinical characteristic, including comorbidities, of patients with acne with a special focus on adult female acne (AFA). This cross-sectional study analyzed the medical records of 354 patients with acne (323 outpatients and 31 hospitalized). Read More

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December 2020

Biologic and Targeted Therapy in the Treatment of Psoriasis - A Retrospective Study from a National Referral Center.

Acta Dermatovenerol Croat 2020 Dec;28(3):127-132

Valentina Saint-Georges, MD, Department of Dermatovenereology , Pula General Hospital, Zagrebačka 32, 52100 Pula, Croatia;

Psoriasis is one of the most common chronic inflammatory skin disorders worldwide with a significant number of patients suffering from moderate to severe disease and requiring systemic therapy. Over the past two decades, better knowledge of disease pathophysiology has translated into treatment advances for both primary disease and its associated comorbidities. However, it is important to review the use of biologic or targeted therapy in a clinical setting in order to understand how to optimize therapeutic results and recognize any unmet needs in this patient subpopulation. Read More

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December 2020

Paraneoplastic Dermatomyositis in a Patient with Metastatic Gastric Carcinoma.

Acta Dermatovenerol Croat 2020 Aug;28(2):120-122

Lyubomir Dourmishev, Address: 1 St. Georgi Sofiiski Blvd., Sofia 1431, Bulgaria;

Dear Editor, Paraneoplastic dermatomyositis is a distinct clinical variant of dermatomyositis (DM) in which the typical cutaneous features and muscle weakness appear before, simultaneously, or after the diagnosis of an internal malignancy. It occurs in approximately one-third of patients with DM, predominantly adults, after the age of 40 (1). Different neoplasms have been described in association with DM, the most common of which are lung, breast, ovarian, gastrointestinal, prostate, and bladder cancers. Read More

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Morbihan Disease - An Old and Rare Entity Still Difficult to Treat.

Acta Dermatovenerol Croat 2020 Aug;28(2):118-119

Associate Professor Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb,, Croatia;

Morbihan disease (MD), also known as Morbihan syndrome, "solid persistent facial edema and erythema", "rosacea lymphedema", and "solid facial edema in acne", is a rare and often unrecognizable entity, that presents with a slow occurrence of persistent lymphoedema of the upper two-thirds of the face (1,2). A 30-year-old woman presented to our Department with persistent, asymptomatic face edema and erythema lasting for 18 months. She was previously treated for rosacea with doxycycline (100 mg/day for four months) without improvement. Read More

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Cutaneous Leiomyoma Mimicking a Keloid.

Acta Dermatovenerol Croat 2020 Aug;28(2):116

Emine Boyuk, MD, Department of Dermatology, Eskişehir Osmangazi University,, Faculty of Medicine, Eskişehir, , Turkey;

Dear Editor, Cutaneous leiomyomas (CL) are rare, benign smooth muscle tumors of the skin (1). There are 3 subtypes with different origins and histopathologic features: piloleiomyoma, genital leiomyoma, and angioleiomyoma (2). Pilar leiomyoma is the most common subtype originating from arrector pili muscles of pilosebaceous unit. Read More

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Dermoscopic Features of Twin Melanomas of the Lower Leg: A Case Report.

Acta Dermatovenerol Croat 2020 Aug;28(2):113-115

Daniela Ledić Drvar, MD, PhD, University Hospital Centre Zagreb Department of Dermatology and Venereology , School of Medicine University of Zagreb , 10000 Zagreb, Šalata 4, Croatia;

Multiple primary malignancies, including melanoma, usually present singly over time rather than simultaneously. Hovewer, approximatelly one third of the patients develop multiple primary melanomas. We present a case of a 57-year-old woman, with two grossly suspicious, unevenly pigmented lesions on her left lower leg measuring up to 8 and 11 mm. Read More

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Epidermolysis Bullosa Acquisita Mimicking Linear IgA Bullous Disease in a 5-year-old Child.

Acta Dermatovenerol Croat 2020 Aug;28(2):109-112

Karen Manuelyan, MD, PhD, "Prof. St. Kirkovich" University Hospital, 2 General Stoletov Str., Stara Zagora, Bulgaria;

We present a case of a 5-year-old child with epidermolysis bullosa acquisita, clinically resembling linear IgA bullous disease. The case demonstrates that autoimmune bullous dermatoses in childhood may show a clinical overlap, which makes the diagnosis based on clinical features highly unreliable. Specific immunofluorescence and immunoserological tests are crucial for precise diagnosis - in our case circulating antibodies against collagen VII were detected using ELISA and indirect immunofluorescence on transfected cells. Read More

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