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    10033 results match your criteria Acta Dermato-Venereologica [Journal]

    1 OF 201

    Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology and Allergology, University Medical Center Utrecht, Room G02.124, Post Box 85500, NL-3508 GA Utrecht, The Netherlands.

    Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology, No.1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China.
    Prostanoids, including prostaglandins (PGs) and thromboxane A2 (TXA2), are a family of lipid-derived autacoids that modulate many physiological systems and pathological contexts. Prostanoids are generated by sequential metabolism of arachidonic acid, catalysed by cyclo-oxygenase, to PGH2, which is then converted to PGD2, PGE2, PGF2α, PGI2 and TXA2, catalysed by their specific synthases. Recent evidence suggests that prostanoids play a role in regulating hair growth. Read More

    Treatment of Scleroedema Adultorum Buschke: A Systematic Review.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology, Jena University Hospital Erfurter Straße 35, DE-07743 Jena, Germany.
    Scleroedema adultorum Buschke is a rare skin disease, which can be divided into 3 subtypes: "classic type", occurring after respiratory infections; a type lacking association with infections; and a type associated with diabetes. Scleroedema adultorum Buschke is characterized by thickening and tightening of the skin, which typically starts at the neck. In half of patients, spontaneous remission may occur. Read More

    Treatment of Cutaneous Pseudolymphoma: A Systematic Review.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology, Jena University Hospital Erfurter Straße 35, DE-07743 Jena, Germany.
    Cutaneous pseudolymphoma (CPL) is a reactive polyclonal T- or B-cell lymphoproliferative process. CPL may appear as localized or disseminated skin lesions. While most cases of CPL are idiopathic, they may also occur as a response to, for example, contact dermatitis, arthropod reactions, and bacterial infections. Read More

    Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    CIC, INSERM U1232, FR-44093 Nantes, France.
    Propionibacterium acnes, a major member of normal skin microbiota, is subdivided into 6 phylotypes: IA1, IA2, IB, IC, II and III. This study investigated P. acnes subgroups on the face and back in patients with severe acne and in healthy controls. Read More

    Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology and Allergy, Herlev and Gentofte University Hospital, University of Copenhagen, Kildegaardsvej 28, DK-2900 Hellerup, Denmark.
    Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort study of the entire Danish population aged ≥ 18 and ≤ 100 years was conducted, followed from 1997 to 2011 by individual-level linkage of nationwide registries. Multivariable adjusted Cox regression models were used to estimate the hazard ratios (HRs) for a composite cardiovascular disease endpoint. Read More

    Risk Factors for Surgical Site Infections in Dermatological Surgery.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology, Maastricht University Medical Centre, P. Debyelaan 25, NL-6229 HX Maastricht, The Netherlands.
    Current literature on risk factors for surgical site infection (SSI) in dermatological surgery in the absence of antibiotic prophylaxis is limited. The aim of this study was to retrospectively evaluate patients presenting for dermatological surgery. A total of 1,977 procedures were reviewed. Read More

    Chronic Prurigo of Nodular Type: A Review.
    Acta Derm Venereol 2017 Aug 23. Epub 2017 Aug 23.
    Center for Chronic Pruritus, Department of Dermatology, University Hospital Münster, Von- Esmarch-Str. 58, DE-48149 Münster, Germany.
    Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules. PN evolves along with chronic pruritus in the context of diverse dermatological, systemic, neurological or psychiatric conditions. Permanent scratching is possibly a major trigger of PN, although its exact pathophysiology remains unclear. Read More

    Light Chain Deposition Disease with Bullous Skin Lesions Mimicking Atypical Bullous Pemphigoid.
    Acta Derm Venereol 2017 Aug 23. Epub 2017 Aug 23.
    Department of Immunology, Hôpital Saint-Louis, Assistance Publique-Hôpitaux, INSERM UMRS_1165, Université Paris Diderot, 1 avenue Claude Vellefaux, FR-75010 Paris, France.

    German Patients' and Physicians' Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare).
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Department of Dermatology, University Medical Center Mannheim, Heidelberg University, DE-68135 Mannheim, Germany.
    Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients' (n = 222) and physicians' (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using the Relative Importance Score (RIS) for each attribute calculated by dividing the attribute's range by the sum of all attribute ranges times 100. Both groups considered Psoriasis Area and Severity Index 90 (PASI 90) to be most important (RIS 21. Read More

    Search for RASA1 Variants in Capillary Malformations of the Legs in 113 Children: Results From the French National Paediatric Cohort CONAPE.
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Department of Dermatology, CHRU Tours, Hospital Trousseau, Avenue de la République, FR-37044, Tours Cedex 9, France.
    Patients with an inherited autosomal-dominant disorder, capillary malformation-arteriovenous malformation (CM-AVM), frequently have mutations in Ras P21 protein activator 1 (RASA1). The aims of this study were to determine the prevalence of germline RASA1 variants in a French multicentre national cohort of children, age range 2-12 years, with sporadic occurrence of capillary malformation (CM) of the legs, whatever the associated abnormalities, and to identify genotype-phenotype correlates. DNA was extracted from leukocytes in blood samples, purified and amplified, and all exons of the RASA1 gene were analysed. Read More

    Granuloma Annulare and Morphea: Correlation with Borrelia burgdorferi Infections and Chlamydia-related Bacteria.
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Department of Dermatology, Allergology and Venereal Diseases, University of Helsinki and Center of Inflammation, Helsinki University Central Hospital, FIN-00029 Helsinki, Finland.
    A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea histology from patients with suspected tick bite was performed. Biopsies were tested for cutaneous Borrelia burgdorferi DNA using PCR. The same biopsies were analysed for tick-borne novel agents, Chlamydia-related bacteria (members of the Chlamydiales order), using a PCR-based method. Read More

    Correlation Between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis Treated with Ustekinumab.
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Department of Dermatology and Allergy, Herlev and Gentofte University Hospital, University of Copenhagen, Kildegaardsvej 28, DK-2900 Hellerup, Denmark.
    Biologic treatment for psoriasis is based on clinical evaluation and patient's quality of life. However, long-term correlation between Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) in real life has not been studied in patients treated with ustekinumab. All patients with psoriasis treated with ustekinumab at our department were included (n = 120) in this study. Read More

    Estimation of Direct Melanoma-related Costs by Disease Stage and by Phase of Diagnosis and Treatment According to Clinical Guidelines.
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Laboratory of Health Care Services and Health Promotion Evaluation, Unit of Hygiene and Public Health, Department of Cardiologic, Vascular, and Thoracic Sciences and Public Health, University of Padova, Via Loredan, 18, IT-35131 Padova, Italy.
    Cutaneous melanoma is a major concern in terms of healthcare systems and economics. The aim of this study was to estimate the direct costs of melanoma by disease stage, phase of diagnosis, and treatment according to the pre-set clinical guidelines drafted by the AIOM (Italian Medical Oncological Association). Based on the AIOM guidelines for malignant cutaneous melanoma, a highly detailed decision-making model was developed describing the patient's pathway from diagnosis through the subsequent phases of disease staging, surgical and medical treatment, and follow-up. Read More

    Fractional Carbon Dioxide Laser as an "Add-on" Treatment for Vitiligo: A Meta-analysis with Systematic Review.
    Acta Derm Venereol 2017 Nov 7. Epub 2017 Nov 7.
    Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
    Treatment of vitiligo is challenging and requires a multidisciplinary approach. Fractional carbon dioxide (CO2) laser as an add-on to conventional treatment has been reported to be effective, but there is no consensus on its use. A systematic review was performed by searching major databases for relevant publications to February 2017. Read More

    Placebo Effects of Open-label Verbal Suggestions on Itch.
    Acta Derm Venereol 2017 Oct 23. Epub 2017 Oct 23.
    Institute of Psychology, Health, Medical and Neuropsychology unit, Leiden University, NL-2300 RB Leiden, The Netherlands.
    Placebo effects are positive outcomes that are not due to active treatment components, which may be elicited even when patients are aware of receiving an inert substance (open-label). This proof-of-principle study investigated for the first time whether open-label placebo effects on itch can be induced by verbal suggestions alone. Ninety-two healthy volunteers were randomized to experimental (open-label suggestions) or control (no suggestions) groups. Read More

    The Pain Quality Assessment Scale for epidermolysis bullosa.
    Acta Derm Venereol 2017 Oct 23. Epub 2017 Oct 23.
    Department of Dermatology, University Medical Center Groningen, Hanzeplein 1, NL-9700 RB Groningen, The Netherlands.
    Pain is one of the most debilitating B symptoms in epidermolysis bullosa (EB) leading to reduced quality of life. Pain in EB comprises both neuropathic and non-neuropathic qualities. An assessment of pain qualities has not formerly been completed in EB. Read More

    Cutaneous Chronic Graft Versus Host Disease Following Allogeneic Haematopoietic Stem Cell Transplantation in Children: A Retrospective Study.
    Acta Derm Venereol 2017 Oct 23. Epub 2017 Oct 23.
    Department of Dermatology, Hadassah-Hebrew University Medical Center, Kiryat Hadassah, POB 12000, Jerusalem, 9112001, Israel.
    Chronic graft versus host disease (cGVHD) is a complication of allogeneic haematopoietic stem cell transplantation (HSCT). The aim of this study was to clinically characterize childhood cutaneous cGVHD. A retrospective study of children treated with HSCT at 2 tertiary medical centres in Israel between 2011 and 2014 was performed. Read More

    Late-onset Erythropoietic Protoporphyria Associated with Myelodysplastic Syndrome Treated with Azacitidine.
    Acta Derm Venereol 2017 Oct 23. Epub 2017 Oct 23.
    Division of Dermatology, Department of Internal Medicine, Kobe University Graduate School of Medicine , Kobe University Graduate School of Medicine, 6500017 5-2, Kusunoki-cho7, Chuo-ku, Kobe-shi, Hyougo, Kobe, Japan.

    Patients' Illness Perception as a Tool to Improve Individual Disease Management in Primary Cutaneous Lymphomas.
    Acta Derm Venereol 2017 Oct 19. Epub 2017 Oct 19.
    Department of Dermatology, Medical University of Vienna, Waehringer Guertel 18-20, AT-1090 Vienna, Austria.
    The Revised Illness Perception Questionnaire (IPQ-R) has been shown to assess illness perception reproducibly in primary cutaneous T-cell lymphomas (CTCL). Illness perception reflects patients' individual concepts of understanding and interpretation of the disease, influencing illness behaviour and health-related quality of life (HRQOL). This study investigated the clinical relevance of the relationships between illness perception, illness behaviour, and HRQOL in CTCL and cutaneous B-cell lymphomas (CBCL). Read More

    Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area.
    Acta Derm Venereol 2017 Oct 19. Epub 2017 Oct 19.
    Department of Dermatology, Tampere University Hospital, PO Box 2000, FIN-33521 Tampere, Finland.
    Dermatitis herpetiformis (DH) is an extra-intestinal manifestation of coeliac disease. The highest currently reported prevalence of DH is in Finland, but knowledge of diagnostic delay is limited. This study investigated the duration of rash prior to diagnosis in 446 patients with DH, analysing the results in 3 periods of 15 years. Read More

    Clinical Characteristics of Pruritus and Pain in Patients with Hidradenitis Suppurativa.
    Acta Derm Venereol 2017 Oct 3. Epub 2017 Oct 3.
    Department of Dermatology, Venereology and Allergology, Medical University, Chałubińskiego 1, PL-50-368 Wrocław, Poland.
    A growing body of research has indicated that pruritus is an important feature of hidradenitis suppurativa (HS). This study evaluated pruritus and pain among 103 patients with HS. Pruritus and pain intensity were assessed with a visual analogue scale, numerical rating scale and 4-item Itch Questionnaire. Read More

    Burden of Aquagenic Pruritus in Polycythaemia Vera.
    Acta Derm Venereol 2017 Oct 3. Epub 2017 Oct 3.
    Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1,, 50-368 Wrocław, Poland.
    Aquagenic pruritus (AP) has a significant influence on quality of life (QoL) in patients with polycythaemia vera. This study analysed the impact of AP on patient well-being in 102 patients with polycythaemia vera. Intensity of pruritus was evaluated using a visual analogue scale (VAS), verbal rating scale (VRS) and a 4-item Itch Questionnaire. Read More

    Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function.
    Acta Derm Venereol 2017 Oct 2. Epub 2017 Oct 2.
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 890-8520 Kagoshima, Japan.
    Atopic dermatitis (AD) is a chronic inflammatory skin disease. Corticosteroids, which are widely used for AD treatment, have adverse effects, and alternative treatments are urgently needed. This study examined the effect of topical application of high-dose glucose on inflamed skin in a murine model of AD. Read More

    Nail Involvement in Alopecia Areata: A Questionnaire-Based Survey of Impact on Quality of Life and Review of the Literature.
    Acta Derm Venereol 2017 Oct 2. Epub 2017 Oct 2.
    Department of Dermatology, Radboud University Nijmegen Medical Center, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands.
    Alopecia areata (AA) is an immune-mediated disease causing temporary or permanent hair loss. Up to 46% of patients with AA also have nail involvement. The aim of this study was to determine the presence, types, and clinical implications of nail changes in patients with AA. Read More

    Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis.
    Acta Derm Venereol 2017 Oct 2. Epub 2017 Oct 2.
    Department of Dermatology, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582, Japan.
    Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-α)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these disorders. Recently, functional activation of the IL-36 receptor (IL-36R) was discovered to be another driving force in the pathogenesis of psoriasis. Read More

    Tailored Therapist-guided Internet-based Cognitive-behavioural Treatment for Psoriasis and Rheumatoid Arthritis: Two Case Reports.
    Acta Derm Venereol 2017 Sep 27. Epub 2017 Sep 27.
    Department of Medical Psychology, Radboud University Medical Center, Nijmegen, The Netherlands.
    Chronic somatic conditions, such as psoriasis, arthritis psoriatica and rheumatoid arthritis, have a large impact on patients’ lives. Tailored therapist-guided internet-based cognitive-behavioural therapy (ICBT) has been shown to be effective in improving physical and psychological well-being in these patients. Two cases are presented here, in order to provide an in-depth illustration of the course and content of this novel treatment and to investigate the therapeutic alliance in an online treatment. Read More

    Development and Validation of the Basal and Squamous Cell Carcinoma Quality of Life Questionnaire.
    Acta Derm Venereol 2017 Sep 27. Epub 2017 Sep 27.
    Department of Dermatology, Erasmus MC University Medical Centre, Postbus 2040, NL-3000 CA Rotterdam, The Netherlands.
    Health-related quality of life (HRQoL) is important in the management of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Disease-specific questionnaires exist, but with important shortcomings. The aim of this study was to develop and validate a questionnaire suitable for use in all patients with BCC and those with SCC. Read More

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