690,103 results match your criteria Acta Carsologica[Journal]

Judging me and you: Task design modulates self-prioritization.

Acta Psychol (Amst) 2021 Jun 8;218:103350. Epub 2021 Jun 8.

School of Psychology, University of Aberdeen, Aberdeen, Scotland, UK.

An extensive literature has revealed the benefits of self-relevance during stimulus processing. Compared to material associated with other persons (e.g. Read More

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A highly selective and sensitive Zn fluorescent sensor based on zinc finger-like peptide and its application in cell imaging.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 2;261:120042. Epub 2021 Jun 2.

School of Chemistry and Chemical Engineering, University of South China, Hengyang, China. Electronic address:

Developing new chemosensors for detection of Zn has attracted great attentions because of the important roles of Zn in biological systems, and it will produce toxic effects with an excessive intake of zinc ion. Metalloproteins are often used as an effective template for the design and development of peptide-based fluorescent sensors. In this study, we designed a new and simple ratiometric fluorescent sensor for Zn, which was based on a zinc finger-like peptide and labeled with a dansyl group, i. Read More

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Fabrication and measurement of fiber optic localized surface plasmon resonance sensor based on gold nanoparticle dimer.

Spectrochim Acta A Mol Biomol Spectrosc 2021 May 29;261:120034. Epub 2021 May 29.

Department of Electronics and Electrical Engineering, Dankook University, Yongin 16890, South Korea. Electronic address:

Fiber optic localized surface plasmon resonance (FO LSPR) sensors capable of portable, real-time, and remote sensing are emerging with the progress of lab-on-fiber technology. However, the small area of the substrate by the optical fiber often restricts the sensitivity of the FO LSPR sensors. To improve the performance of the FO LSPR sensors, it is necessary to enhance the interactions between incident light and plasmonic nanostructures within a defined region. Read More

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Density functional study of trans,trans,trans-[Pt(N)(OH)(Py)] on molecular structure and vibrational spectroscopy.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 2;261:120022. Epub 2021 Jun 2.

School of Life Science, Ludong University, Yantai, Shandong 264025, China. Electronic address:

This study records the selection of the best combination of geometric optimization and frequency calculation methods of the trans,trans,trans-[Pt(N)(OH)(py)](FM-190) by using different density functional calculation methods and basis sets. The results show that the CAM-B3LYP/SDD method has the best fit to the experimental data for geometric optimization, while the LSDA/SDD method has better performance in frequency calculation, and the infrared vibration peak is assigned. In addition, the calculated HOMO and LUMO show the energy gap and the internal charge transfer of this complex. Read More

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A novel 1,8-naphthalimide-based Cu ion fluorescent probe and its bioimaging application.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 1;261:120037. Epub 2021 Jun 1.

School of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221116, People's Republic of China. Electronic address:

A new 1,8-naphthalimide-based Schiff base compound, named as (Z)-2-butyl-6-(((2-hydroxyphenyl)imino)methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (BHBD), has been simply synthesized with high yields. BHBD can be employed as a "turn-on" fluorescent probe for Cu ion with high sensitivity, high selectivity and relatively low detection limit (0.48 × 10 M). Read More

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Identification and composition of carbonate minerals of the calcite structure by Raman and infrared spectroscopies using portable devices.

Spectrochim Acta A Mol Biomol Spectrosc 2021 May 26;261:119980. Epub 2021 May 26.

GeoRessources Laboratory -Université de Lorraine, Faculté des Sciences et Technologies, BP 70239, F-54506 Vandœuvre-lès-Nancy, France.

A portable Raman device with a 532 nm excitation laser and a portable infrared spectrometer with ATR (Attenuated Total Reflection) mode were used to analyse the spectral features associated with the identification and compositional variation of Ca-Mg-Fe-Mn natural carbonate minerals with a calcite structure (calcite, ankerite, dolomite, siderite, rhodochrosite, and magnesite). A systematic study of the variations of the peak positions with various compositional ratios was carried out. Most of the band positions were shifted to lower wavenumbers with increasing ionic radius or atomic mass of the divalent cations but the band of the translational lattice (T) mode in Raman and the symmetric bending (ν) band in the mid-infrared were the most sensitive. Read More

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FTIR spectroscopy with machine learning: A new approach to animal DNA polymorphism screening.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 1;261:120036. Epub 2021 Jun 1.

Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, 79070-900 Campo Grande, MS, Brazil. Electronic address:

Technological advances in recent decades, especially in molecular genetics, have enabled the detection of genetic DNA markers associated with productive characteristics in animals. However, the prospection of polymorphisms based on DNA sequencing is still expensive for the reality of many food-producing regions around the world, such as Brazil, demanding more accessible prospecting methods. In the present study, the Fourier transform infrared spectroscopy (FTIR) and machine learning algorithms were used to identify single nucleotide polymorphism (SNP) in animal DNA. Read More

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Label-free surface-enhanced Raman spectroscopy for diagnosis and analysis of serum samples with different types lung cancer.

Spectrochim Acta A Mol Biomol Spectrosc 2021 May 26;261:120021. Epub 2021 May 26.

School of Physics, Dalian University of Technology, Dalian, 116023, People's Republic of China.

Screening and detection of early lung cancer is important for diagnosis and prognosis. Intervention in early stage of lung cancer can significantly improve the cure and survival of patients. Surface-enhanced Raman spectroscopy (SERS) is an increasingly popular method of diagnosing cancer. Read More

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The involvement of translationally controlled tumor protein during lamb rumen epithelium development.

Acta Histochem 2021 Jun 8;123(5):151737. Epub 2021 Jun 8.

Institute of Animal Husbandry and Veterinary, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China. Electronic address:

Early weaning is usually applied to improve the reproductive efficiency of sheep in mutton production, while the development of rumen is of vital importance for sheep weaning age. Translationally controlled tumor protein (TCTP) is a highly conserved protein which participates in multiple tissue and organ development. Thus, we hypothesized that TCTP was involved in sheep rumen development. Read More

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DGAT2 Stability is Increased in Response to DGAT1 Inhibition in Gene Edited HepG2 Cells.

Biochim Biophys Acta Mol Cell Biol Lipids 2021 Jun 8:158991. Epub 2021 Jun 8.

Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada. Electronic address:

In eukaryotic organisms, two unrelated acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes, DGAT1 and DGAT2, catalyze the final step of the triacylglycerol biosynthetic pathway. Both enzymes are highly expressed in lipogenic tissues, such as adipose tissue, small intestine and the liver. DGAT2 has a prominent role in hepatocyte lipid metabolism synthesizing triacylglycerols that are utilized for very low-density lipoprotein assembly. Read More

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Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.

Biochim Biophys Acta Gene Regul Mech 2021 Jun 8:194723. Epub 2021 Jun 8.

Key Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, Fishery College, Huazhong Agricultural University, Wuhan 430070, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. Electronic address:

The study characterized their regulatory functions of four znt members (znt1, znt2, znt6 and znt8) in Zn homeostasis in vertebrates. We found that the -1281/-1296 bp locus on the znt1 promoter, the -1/-16 bp locus on the znt2 promoter, the -825/-839 bp locus on the znt6 promoter, the -165/-180 bp locus and the -274/-292 bp STAT3 locus on the znt8 promoter were functional MTF-1 binding sites and had metal responsive element (MRE). Zn incubation increased activities of four znt promoters, which was mediated by MRE sites on znt1, znt2, znt6 and znt8 promoters and by STAT3 binding site on znt8 promoter. Read More

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Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines.

Acta Biomater 2021 Jun 8. Epub 2021 Jun 8.

Biomedical Research Institute Sant Pau (IIB Sant Pau), Sant Antoni Mª Claret 167, 08025 Barcelona Spain; Josep Carreras Leukaemia Research Institute (IJC Campus Sant Pau), Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), C/ Monforte de Lemos 3-5, 28029 Madrid, Spain; Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. Electronic address:

Green fluorescent protein (GFP) is a widely used scaffold for protein-based targeted nanomedicines because of its high biocompatibility, biological neutrality and outstanding structural stability. However, being immunogenicity a major concern in the development of drug carriers, the use of exogenous proteins such as GFP in clinics might be inadequate. Here we report a human nidogen-derived protein (HSNBT), rationally designed to mimic the structural and functional properties of GFP as a scaffold for nanomedicine. Read More

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Isolation methods commonly used to study the liposomal protein corona suffer from contamination issues.

Acta Biomater 2021 Jun 8. Epub 2021 Jun 8.

DTU Health Tech, Department of Health Technology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark. Electronic address:

The liposomal protein corona has been the focus of numerous studies, but there is still no consensus regarding its extent and composition. Rather, the literature is full of conflicting reports on the matter. To elucidate whether there could be a methodological explanation for this, we here scrutinize the efficiency of three commonly used liposome isolation methods at isolating stealth liposomes from human plasma. Read More

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Cancer Cell Migration in Collagen-hyaluronan Composite Extracellular Matrices.

Acta Biomater 2021 Jun 8. Epub 2021 Jun 8.

Department of Chemical and Biological Engineering, Iowa State University; Department of Genetics, Development and Cell Biology, Iowa State University. Electronic address:

Hyaluronan (HA) is a key component in the tumor microenvironment (TME) that participates in cancer growth and invasiveness. While the molecular weight (MW) dependent properties of HA can cause tumor-promoting and -repressing effects, the elevated levels of HA in the TME impedes drug delivery. The degradation of HA using hyaluronidases (HYALs), resulting in fragments of HA, is a way to overcome this, but the consequences of changes in HA molecular weight and concentration is currently unknown. Read More

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Human Neutrophil FcγRIIIb Regulates Neutrophil Extracellular Trap Release in Response to Electrospun Polydioxanone Biomaterials.

Acta Biomater 2021 Jun 8. Epub 2021 Jun 8.

Department of Biomedical Engineering, University of Memphis, 3806 Norriswood Avenue, Memphis, TN, USA. Electronic address:

During the acute inflammatory response, the release of neutrophil extracellular traps (NETs) is a pro-inflammatory, preconditioning event on a biomaterial surface. Therefore, regulation of NET release through biomaterial design is one strategy to enhance biomaterial-guided in situ tissue regeneration. In this study, IgG adsorption on electrospun polydioxanone biomaterials with differing fiber sizes was explored as a regulator of in vitro human neutrophil NET release. Read More

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The interaction of SET and protein phosphatase 2A as target for cancer therapy.

Biochim Biophys Acta Rev Cancer 2021 Jun 8:188578. Epub 2021 Jun 8.

Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo, Av.Prof. Lineu Prestes, 1730, room 136, Biomedicas IV Building, São Paulo CEP 05508-000, SP, Brazil. Electronic address:

In cancer cells, tumor suppressor proteins loss-of-function are usually the result of genetic mutations. Protein Phosphatase 2A is a tumor suppressor that inactivates several signaling pathways through removal of phosphate residues important for other proteins stability and/or activation. Different from other tumor suppressors, PP2A is, in many cancer types, inactivated by endogenous inhibitors. Read More

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New ratio as a useful marker for early diagnosis of proximal urea cycle disorders.

Clin Chim Acta 2021 Jun 8. Epub 2021 Jun 8.

Expanded Newborn Screening Laboratory, Referral Center for Inherited Metabolic Disorders, Pediatric Clinical, University-Hospital "Gaspare Rodolico - San Marco", Catania, Italy; Clinical and Experimental Medicine Department, University of Catania, Catania, Italy.

Background And Aims: Proximal urea cycle disorders (PUCDs) are not included in most newborn screening programs due to the lack of adequate markers to monitor. Failure to alter citrulline and glutamine levels, the prognostic markers commonly used, can results in high false negative. Therefore, new biomarkers, prognostic of PUCDs, are strongly desirable. Read More

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Comparison of Cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy.

Clin Chim Acta 2021 Jun 8. Epub 2021 Jun 8.

Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

Renal function is associated with postoperative residual hypertension in aldosterone-producing adenoma(APA) patients. Cystatin C-based glomerular filtration rate (GFR) can more accurately estimate renal function than creatinine-based methods. However, which renal function estimation method can more accurately predict postoperative hypertension in APA patients is still unknown. Read More

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Comment on "High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin America."


Acta Paediatr 2021 Jun 11. Epub 2021 Jun 11.

We read the article "High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin America" by Yock-Corrales.A et.al. Read More

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Severe recalled labor pain and elective cesarean section in a subsequent delivery: a cohort study of Norwegian parous women.

Acta Obstet Gynecol Scand 2021 Jun 11. Epub 2021 Jun 11.

Institute and Policlinic of Occupational and Social Medicine, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.

Introduction: Some women keep on recalling intense labor pain experienced at childbirth to a degree that it may negatively affect their life during the postpartum period or lead them to request a cesarean section (CS) in the subsequent delivery. This longitudinal study aimed to assess the impact of severe recalled labor pain from the previous birth on the preference of and delivery by an elective CS in the subsequent delivery. Further, we investigated if co-occurring maternal demographic, somatic, and mental health factors related to the previous and subsequent delivery explain parts of a potential association. Read More

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miR-379-5p inhibits proliferation and invasion of the endometrial cancer cells by inhibiting expression of ROR1.

Acta Biochim Pol 2021 Jun 11. Epub 2021 Jun 11.

Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, China.

Endometrial cancer is a common gynecological malignancy, and the incidence of this disease has increased in recent years. Recently, some studies suggested that the expression of miR-379-5p suppressed the metastasis of breast cancer cells. However, whether the expression of miR-379-5p could affect the proliferation, migration and invasion of endometrial cancer is unclear. Read More

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First Record of the Cymothoid Isopod Nerocila exocoeti Pillai, 1954 (Crustacea, Isopoda) in the South-West Indian Ocean and First Record of a Perciform Host, Echeneis naucrates, for this Species.

Acta Parasitol 2021 Jun 11. Epub 2021 Jun 11.

Save Our Seas Foundation-D'Arros Research Centre (SOSF-DRC), Rue Philippe Plantamour 20, 1201, Geneva, Switzerland.

Purpose: Cymothoid isopods of the genus Nerocila are generally poorly known. The aim of this work was to document the first record of cymothoid isopod Nerocila exocoeti for the South-West Indian Ocean, representing a significant westward range extension for this species.

Methods: A single adult, female N. Read More

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IgG Subclass Analysis in Patients with Chagas Disease 4 Years After Benznidazole Treatment.

Acta Parasitol 2021 Jun 11. Epub 2021 Jun 11.

Department of Microbiology, Immunology and Parasitology, Institute of Biological and Natural Sciences, Federal University of Triângulo Mineiro. Uberaba, Minas Gerais, Brazil.

Background: In humans, Trypanosoma cruzi infection is controlled by a complex immune response. Immunoglobulin G (IgG) is important for opsonizing blood trypomastigotes, activating the classic complement pathway, and reducing parasitemia. The trypanocidal activity of benznidazole is recognized, but its effects on the prevention and progression of Chagas disease is not well understood OBJECTIVE: We aimed to evaluate the levels of total IgG and cross-specific IgG subclasses in patients with chronic Chagas disease of different clinical forms before and after 4 years of benznidazole treatment. Read More

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Morphological and Molecular Identification of Emerged Lophomonas blattarum Infection in Mazandaran Province, Northern Iran: First Registry-Based Study.

Acta Parasitol 2021 Jun 11. Epub 2021 Jun 11.

Toxoplasmosis Research Center, Communicable Diseases Institute, Iranian National Registry Center for Lophomoniasis (INRCL), Mazandaran University of Medical Sciences, Farah-Abad Road, P.O Box: 48471- 91971, Sari, Iran.

Background: In the last decade, several cases of bronchopulmonary lophomoniasis (BPL) have been recorded. Little information is available about epidemiological aspects on Lophomonas infection among BPL patients. The present study was aimed to investigate the prevalence of Lophomonas spp. Read More

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Letter re: The exact number of misplacements is essential for the reproducibility of statistical findings by Mansoor et al.

Ghassan Kerry

Acta Neurochir (Wien) 2021 Jun 11. Epub 2021 Jun 11.

Department of Neurosurgery, Paracelsus Medical University, Breslauer Strasse 201, 90471, Nuremberg, Germany.

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Ethylenediamine-bound magnetite nanoparticles as dual function colorimetric sensor having charge transfer and nanozyme activity for TNT and tetryl detection.

Mikrochim Acta 2021 Jun 11;188(7):228. Epub 2021 Jun 11.

Engineering Faculty, Chemistry Department, Istanbul University-Cerrahpaşa, Avcilar, Istanbul, Turkey.

A reusable, low-cost, and convenient ethylenediamine (EDA)-bound magnetite nanoparticles (MNPs)-based colorimetric sensor has been developed for dual function colorimetric determination of nitroaromatic explosives such as TNT and tetryl. Colorimetric detection of analytes may occur through two independent routes: (1) nano-FeO- EDA- NH as σ-donor may interact with the σ- and π-acceptor aromatic-poly(NO) groups to produce a colored charge-transfer (CT) complex; (2) nano-FeO-EDA-NH as a Fenton-type nanozyme may generate reactive species that comprise hydroxyl radicals (OH) with HO to oxidize 3,3',5,5'-tetramethylbenzidine (TMB) to a blue-colored diimine (oxTMB-TMB) CT complex, where this color is bleached with TNT/tetryl because of donor-acceptor interactions between the explosive -NO groups and the -NH group of FeO-EDA nanoparticles of restricted nanozyme activity. Both methods can quantify TNT well below the EPA recommended TNT residential screening level in soil, LOD being in the micromolar range. Read More

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The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.

Acta Neuropathol 2021 Jun 11. Epub 2021 Jun 11.

Department of Anatomy and Neurosciences, Clinical Neuroanatomy and Biobanking, Amsterdam Neuroscience, Amsterdam UMC, Location VU University Medical Center, O2 building, room 13 E11, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.

Various post-translationally modified (PTM) proteoforms of alpha-synuclein (aSyn)-including C-terminally truncated (CTT) and Serine 129 phosphorylated (Ser129-p) aSyn-accumulate in Lewy bodies (LBs) in different regions of the Parkinson's disease (PD) brain. Insight into the distribution of these proteoforms within LBs and subcellular compartments may aid in understanding the orchestration of Lewy pathology in PD. We applied epitope-specific antibodies against CTT and Ser129-p aSyn proteoforms and different aSyn domains in immunohistochemical multiple labelings on post-mortem brain tissue from PD patients and non-neurological, aged controls, which were scanned using high-resolution 3D multicolor confocal and stimulated emission depletion (STED) microscopy. Read More

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Capillary basement membrane reduplication in myositis patients with mild clinical features of systemic sclerosis supports the concept of 'scleromyositis'.

Acta Neuropathol 2021 Jun 11. Epub 2021 Jun 11.

Division of Rheumatology, Centre Hospitalier de l'Université de Montréal (CHUM); CHUM Research Center; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.

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Comparison of viscocanalostomy plus suture-assisted near-360-degree trabeculotomy and viscocanalostomy plus rigid probe trabeculotomy in primary congenital glaucoma.

Acta Ophthalmol 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Purpose: To compare the efficacy and safety of viscocanalostomy plus near-360-degree suture trabeculotomy (VST) with viscocanalostomy plus rigid probe trabeculotomy (VT) in treating primary congenital glaucoma (PCG) over a one-year follow-up.

Methods: This consecutive retrospective study included patients with PCG confirmed within 3 years of age from March 2017 to October 2019. Efficacy was evaluated by comparing the postoperative intraocular pressure (IOP) curve and the success rate at one year after surgery. Read More

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Advances in exosome therapies in ophthalmology-From bench to clinical trial.

Acta Ophthalmol 2021 Jun 11. Epub 2021 Jun 11.

Faculty of Life Sciences & Medicine, King's College London, London, UK.

During the last decade, the fields of advanced and personalized therapeutics have been constantly evolving, utilizing novel techniques such as gene editing and RNA therapeutic approaches. However, the method of delivery and tissue specificity remain the main hurdles of these approaches. Exosomes are natural carriers of functional small RNAs and proteins, representing an area of increasing interest in the field of drug delivery. Read More

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