857 results match your criteria Acta Cardiologica Sinica[Journal]


Clinical Efficacy and Safety of Reduced-Dose Prasugrel versus Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Acta Cardiol Sin 2022 Jul;38(4):425-434

Department of Pharmacy.

Objectives: This systematic review and meta-analysis of randomized controlled trials (RCTs) compared the clinical efficacy and safety of reduced-dose prasugrel (loading dose: 20 mg; daily maintenance dose: 3.75 mg) and clopidogrel in patients undergoing percutaneous coronary intervention (PCI).

Methods: PubMed, Embase, and the Cochrane Library database were searched for relevant articles from inception to March 8, 2021. Read More

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Performance of the EuroSCORE II Model in Predicting Short-Term Mortality of General Cardiac Surgery: A Single-Center Study in Taiwan.

Acta Cardiol Sin 2022 Jul;38(4):495-503

Department of Cardiovascular Surgery, Kaohsiung Veterans General Hospital.

Background: The latest European System for Cardiac Operative Risk Evaluation (EuroSCORE) II is a well-accepted risk evaluation system for mortality in cardiac surgery in Europe.

Objectives: To determine the performance of this new model in Taiwanese patients.

Methods: Between January 2012 and December 2014, 657 patients underwent cardiac surgery at our institution. Read More

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Effects of Ivabradine on Patients with Depressed Left Ventricular Function after Cardiac Resynchronization Therapy.

Acta Cardiol Sin 2022 Jul;38(4):475-484

Faculty of Medicine, Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei.

Background: The potential synergistic effect of ivabradine and cardiac resynchronization therapy (CRT) in heart failure (HF) patients has rarely been studied. We aimed to evaluate the clinical benefits of ivabradine in patients with left ventricular dysfunction following CRT implantation.

Methods: Two hundred and thirty-one patients receiving CRT were consecutively enrolled between January 2014 and December 2018 from two HF centers. Read More

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Future Perspectives of Pulmonary Hypertension Treatment.

Acta Cardiol Sin 2022 Jul;38(4):435-442

Division of Cardiology, Department of Internal Medicine, Chi-Mei Medical Center.

Since the discovery of three major pathophysiological mechanisms of pulmonary arterial hypertension (PAH), including prostacyclin, endothelin and nitric oxide pathways, the therapeutic options for PAH have increased. Nevertheless, despite these advances, the prognosis remains unsatisfactory for many patients with PAH. With the progress of both pre-clinical and clinical research on PAH, several novel therapeutic targets have been identified for the treatment of PAH. Read More

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Delta Increment in Pacing QRS Duration Predicts Cardiovascular Mortality in Patients with Pre-Existing Bundle Branch Block Receiving Permanent Pacemakers.

Acta Cardiol Sin 2022 Jul;38(4):504-515

Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.

Background: The clinical implication of pre-existing intraventricular conduction disturbance (IVCD) in permanent pacemaker (PPM) recipients is unknown.

Objectives: To explore the clinical outcomes in patients with pre-existing IVCD after implantation of PPMs.

Methods: A total of 1424 patients who received PPMs were categorized into three groups by pre-procedural electrocardiography: patients without IVCD (n = 1045), patients with right bundle branch block (RBBB) (n = 309), and patients with left bundle branch block (LBBB) (n = 70). Read More

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Risks of Ventricular Tachyarrhythmia and Mortality in Patients with Amyloidosis - A Long-Term Cohort Study.

Acta Cardiol Sin 2022 Jul;38(4):464-474

Heart Rhythm Center and Division of Cardiology, Taipei Veterans General Hospital.

Background: The presence of ventricular tachycardia (VT) is associated with higher mortality. The annual incidence of VT after a diagnosis of amyloidosis and the associated cardiovascular (CV) outcomes have not been well assessed in a large cohort.

Methods: A total of 12,139 amyloidosis patients were identified from the Taiwan National Health Insurance Research Database. Read More

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Vascular Trauma in the Extremities: Factors Associated with the Outcome and Assessment of Amputation Indexes.

Acta Cardiol Sin 2022 Jul;38(4):455-463

Division of Cardiovascular Surgery.

Background: Traumatic vascular injury in the extremities may be associated with a low mortality rate but can lead to limb loss that seriously affects patients' functionality. Multiple scoring systems have been designed to evaluate the prognosis, but none are 100% predictive. The management of traumatic vascular injury remains challenging and depends mostly on the surgeon's experience. Read More

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An Effective Strategy to Activate Physicians to Promote High Cardiovascular Risk Patients to Quit Smoking.

Acta Cardiol Sin 2022 Jul;38(4):521-525

Cardiovascular Center, MacKay Memorial Hospital, Taipei & MacKay Medical College, New Taipei City.

Background: Adult patients cared for by cardiologists, neurologists, and diabetologists are highly vulnerable to cardiovascular diseases (CVDs), which are worsened by smoking. In the past, physicians of these three specialties at major hospitals in Taiwan always referred patients to family medicine and chest medicine departments for smoking cessation programs. However, the participation rate in these programs was unsatisfactory. Read More

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A Tragic Case with Multifocal Cerebral, Coronary and Abdominal Aneurysms.

Acta Cardiol Sin 2022 Jul;38(4):546-548

Department of Internal Medicine, College of Medicine, National Taiwan University.

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Effects of Addition of Inspiratory Muscle Training to Exercise-Based Cardiac Rehabilitation on Inspiratory Muscle Strength, Peak Oxygen Consumption, and Selected Hemodynamics in Chronic Heart Failure.

Acta Cardiol Sin 2022 Jul;38(4):485-494

Department of Physiotherapy, National Heart Institute, Giza, Egypt.

Background: Evidence supports the clinical benefits of isolated inspiratory muscle training (IMT) in patients with chronic heart failure (CHF); however, the rationale of IMT in combination with exercise training in cardiac rehabilitation settings for CHF has yet to be confirmed.

Objective: This study aimed to assess the effect of the addition of IMT in combination with aerobic/resistance training (AT/RT) on maximal inspiratory pressure (PImax), peak oxygen consumption (VO), selected hemodynamic variables, and health-related quality of life (HRQoL) compared to sham-IMT combined with AT/RT in patients with CHF.

Methods: Twenty-five male patients with CHF completed a 6-month cardiac rehabilitation program of either a sham-IMT/AT/RT program (control group, 51. Read More

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A Novel Variant Gene in Relation with Hereditary Pulmonary Arterial Hypertension Combined with Pulmonary Arteriovenous Malformations.

Acta Cardiol Sin 2022 Jul;38(4):542-545

Pulmonary Hypertension Interventional Medicine, Division of Cardiology, Cardiovascular Center / Department of Internal Medicine, MacKay Memorial Hospital.

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A Cardiac Rehabilitation Program Increases the Acute Response of Endothelial Progenitor Cells to Maximal Exercise in Heart Failure Patients.

Acta Cardiol Sin 2022 Jul;38(4):516-520

Clinical Ergospirometry, Exercise & Rehabilitation Laboratory, "Evaggelismos" General Hospital, School of Medicine, National and Kapodistrian University of Athens.

Purpose: The purpose of this study was to investigate the effect of a cardiac rehabilitation program on the acute response on endothelial progenitor cells and circulating endothelial cells after maximal exercise in patients with chronic heart failure of different severity.

Methods: Forty-four chronic heart failure patients were enrolled in a 36-session cardiac rehabilitation program. All patients underwent an initial maximal cardiopulmonary exercise test before and a final maximal cardiopulmonary exercise test after the cardiac rehabilitation program. Read More

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Massive Coronary Stent Thrombosis Treated with Ultra-Slow Thrombolytic Therapy in a Patient with Coronavirus Disease 2019.

Acta Cardiol Sin 2022 Jul;38(4):536-538

Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.

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Dual versus Single Antiplatelet Therapy in Medically Treated Acute Myocardial Infarction Patients with Baseline Thrombocytopenia - Insights from a Multi-Institute Cohort Study.

Acta Cardiol Sin 2022 Jul;38(4):443-454

Division of Cardiology, Department of Internal Medicine.

Background: The safety and efficacy of dual antiplatelet therapy (DAPT) in medically treated acute myocardial infarction (AMI) patients with baseline thrombocytopenia (platelet count < 150 × 10/uL) are unclear.

Methods: In this multi-institute retrospective cohort study, we included 468 patients with medically treated AMI with baseline thrombocytopenia and separated them into single antiplatelet therapy (SAPT) and DAPT groups according to the discharge anti-thrombotic strategy. The primary outcome was net clinical adverse events (NACEs), defined as a composite of death, ischemic events (myocardial infarction, ischemic stroke, and transient ischemic attack), and major bleeding within 30 days. Read More

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Heart Failure and Polycythemia: A Case Report and Literature Review.

Acta Cardiol Sin 2022 Jul;38(4):532-535

Division of Cardiovascular Medicine, Department of Internal Medicine, Chi-Mei Medical Center.

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Wire Transfer from the Femoral to Axillary Vein to Implant a Coronary Sinus Lead.

Acta Cardiol Sin 2022 May;38(3):405-408

Department of Cardiology, Division of Arrhythmia and Electrophysiology, University of Health Sciences, Yuksek Ihtisas Cardiovascular Building, Ankara City Hospital, Ankara, Turkey.

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Detecting Patent Foramen Ovale after Cryptogenic Stroke - A Single Center Experience in Taiwan.

Acta Cardiol Sin 2022 May;38(3):373-380

Children's Medical Center, Taichung Veterans General Hospital.

Background: Cryptogenic strokes related to a patent foramen ovale (PFO) in young patients have been reported. Percutaneous transcatheter occlusion is considered a safe and effective method for achieving PFO closure. Here, we present our experience of PFO closure in a series of young patients diagnosed with cryptogenic stroke. Read More

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Prognostic Value of Apical Sparing of Longitudinal Strain in Patients with Symptomatic Aortic Stenosis.

Acta Cardiol Sin 2022 May;38(3):341-351

Department of Cardiology, University of Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Background: Older patients with aortic stenosis (AS) have a higher incidence of wild-type transthyretin cardiac amyloidosis (ATTR-CA). This study aimed to determine whether apical sparing of longitudinal strain (LS) could help diagnose ATTR-CA and provide useful prognostic information in symptomatic AS.

Methods: We performed vendor-independent two-dimensional speckle-tracking analysis of regional and global left ventricular LS in 16 patients with ATTR-CA and 31 patients with non-obstructive hypertrophic cardiomyopathy to determine the best cutoff value of the apical sparing ratio (APSR) for diagnosing ATTR-CA. Read More

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Time Management in Chronic Total Occlusion Percutaneous Coronary Interventions: When Do We Need to Change the Crossing Strategy?

Acta Cardiol Sin 2022 May;38(3):334-340

Department of Invasive Cardiology, Meshalkin National Medical Research Center, Ministry of Health of Russian Federation, Novosibirsk, Russia.

Background: Most complex chronic total occlusions (CTOs) require the utilization of multiple recanalization strategies. However, data on wire manipulation time within CTO percutaneous coronary intervention (PCI) are limited.

Objectives: We sought to investigate the impact of crossover time between crossing strategies on CTO PCI technical success. Read More

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Acute ST-Segment Elevation Myocardial Infarction Happened Within 2 Hours after First Dose of COVID-19 Vaccine.

Acta Cardiol Sin 2022 May;38(3):417-420

Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University.

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Prognostic Value of Nutritional Indexes in Evaluating the 1-Year Results after Implantation of the Carillon Mitral Contour System.

Acta Cardiol Sin 2022 May;38(3):362-372

Department of Cardiology, Gulhane Training and Research Hospital, Ankara, Turkey.

Background: The prognostic importance of nutritional indexes has been shown in some diseases. We aimed to examine the prognostic value of these indexes in patients implanted with the Carillon Mitral Contour System (CMCS).

Methods: Fifty-four patients who underwent successful CMCS implantation were evaluated. Read More

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A Novel Electrocardiographic Score Predicts the Severity of Coronary Artery Disease and Clinical Outcomes in Patients with Non-ST Segment Elevation Myocardial Infarction.

Acta Cardiol Sin 2022 May;38(3):326-333

Department of Cardiology, Kafkas University School of Medicine, Kars, Turkey.

Background: There are many electrocardiographic (ECG) changes in non-ST segment elevation myocardial infarction (NSTEMI). However, the diagnostic power is limited in determining the severity of coronary artery disease (CAD) and clinical outcomes.

Objective: This study investigated the role of a risk-based ECG score in predicting the severity of CAD and clinical outcomes in NSTEMI patients. Read More

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Ictal Asystole in a Patient with Right Temporal Lobe Epilepsy.

Acta Cardiol Sin 2022 May;38(3):400-404

Department of Neurology, Koc University Hospital, Istanbul, Turkey.

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Lipoprotein(a) is Associated with Cardiovascular Events in Low Risk Males: Results from a Health Checkup Cohort with Long-Term Follow-Up.

Acta Cardiol Sin 2022 May;38(3):381-390

Division of Cardiology, Chang Gung Memorial Hospital Linkou Medical Center and Chang Gung University.

Objective: Elevated lipoprotein(a) level is an independent risk factor for atherosclerotic cardiovascular disease. However, the strength of this association in healthy individuals is unknown.

Methods: In this retrospective cohort study, we reviewed medical records obtained from a Health Examination Program. Read More

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Protocolized Post-Cardiac Arrest Care with Targeted Temperature Management.

Acta Cardiol Sin 2022 May;38(3):391-399

Department of Emergency Medicine.

Improvements in teamwork and resuscitation science have considerably increased the success rate of cardiopulmonary resuscitation. Cerebral injury, myocardial dysfunction, systemic ischemia and reperfusion response, and precipitating pathology after the return of spontaneous circulation (ROSC) constitute post-cardiac arrest syndrome. Because the entire body is involved in cardiac arrest and the early post-arrest period, protocolized post-arrest care consisting of cardiovascular optimization, ventilation and oxygenation adjustment, coronary revascularization, targeted temperature management (TTM), and control of seizures and blood sugar would benefit survival and neurological outcomes. Read More

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2022 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension.

Acta Cardiol Sin 2022 May;38(3):225-325

Division of Cardiology, Department of Internal Medicine Kaohsiung Medical University Hospital.

Hypertension is the most important modifiable cause of cardiovascular (CV) disease and all-cause mortality worldwide. Despite the positive correlations between blood pressure (BP) levels and later CV events since BP levels as low as 100/60 mmHg have been reported in numerous epidemiological studies, the diagnostic criteria of hypertension and BP thresholds and targets of antihypertensive therapy have largely remained at the level of 140/90 mmHg in the past 30 years. The publication of both the SPRINT and STEP trials (comprising > 8,500 Caucasian/African and Chinese participants, respectively) provided evidence to shake this 140/90 mmHg dogma. Read More

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