716 results match your criteria Acta Biotheoretica[Journal]


Control by Viability in a Chemotherapy Cancer Model.

Acta Biotheor 2019 Apr 4. Epub 2019 Apr 4.

TSI Team, Faculty of Sciences, University Moulay Ismail, Meknes, Morocco.

The aim of this study is to provide a feedback control, called the Chemotherapy Protocol Law, with the purpose to keep the density of tumor cells that are treated by chemotherapy below a "tolerance level" [Formula: see text], while retaining the density of normal cells above a "healthy level" [Formula: see text]. The mathematical model is a controlled dynamical system involving three nonlinear differential equations, based on a Gompertzian law of cell growth. By evoking viability and set-valued theories, we derive sufficient conditions for the existence of a Chemotherapy Protocol Law. Read More

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http://dx.doi.org/10.1007/s10441-019-09344-0DOI Listing
April 2019
1 Read

Mathematical Modeling of Substrates Fluxes and Tumor Growth in the Brain.

Acta Biotheor 2019 Mar 13. Epub 2019 Mar 13.

Laboratoire de Mathématiques et Applications, UMR CNRS 7348, SP2MI, Equipe DACTIM-MIS, Université de Poitiers, Boulevard Marie et Pierre Curie - Téléport 2, 86962, Chasseneuil Futuroscope Cedex, France.

The aim of this article is to show how a tumor can modify energy substrates fluxes in the brain to support its own growth. To address this question we use a modeling approach to explain brain nutrient kinetics. In particular we set up a system of 17 equations for oxygen, lactate, glucose concentrations and cells number in the brain. Read More

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http://dx.doi.org/10.1007/s10441-019-09343-1DOI Listing

An Organisational Approach to Biological Communication.

Acta Biotheor 2019 Feb 2. Epub 2019 Feb 2.

Department of Logic and Philosophy of Science, IAS-Research Centre for Life, Mind and Society, University of the Basque Country (UPV/EHU), Avenida de Tolosa 70, 20018, Donostia-San Sebastian, Spain.

This paper aims to provide a philosophical and theoretical account of biological communication grounded in the notion of organisation. The organisational approach characterises living systems as organised in such a way that they are capable to self-produce and self-maintain while in constant interaction with the environment. To apply this theoretical framework to the study of biological communication, we focus on a specific approach, based on the notion of influence, according to which communication takes place when a signal emitted by a sender triggers a change in the behaviour of the receiver that is functional for the sender itself. Read More

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http://dx.doi.org/10.1007/s10441-019-09342-2DOI Listing
February 2019
1 Read

The Coherence of Evolutionary Theory with Its Neighboring Theories.

Authors:
Seungbae Park

Acta Biotheor 2019 Jan 24. Epub 2019 Jan 24.

Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.

Evolutionary theory coheres with its neighboring theories, such as the theory of plate tectonics, molecular biology, electromagnetic theory, and the germ theory of disease. These neighboring theories were previously unconceived, but they were later conceived, and then they cohered with evolutionary theory. Since evolutionary theory has been strengthened by its several neighboring theories that were previously unconceived, it will be strengthened by infinitely many hitherto unconceived neighboring theories. Read More

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http://dx.doi.org/10.1007/s10441-019-09341-3DOI Listing
January 2019

Multidrug Therapy for HIV Infection: Dynamics of Immune System.

Acta Biotheor 2018 Dec 4. Epub 2018 Dec 4.

Department of Mathematics, Kurukshetra University, Kurukshetra, Haryana, India.

A mathematical model of the dynamics of the immune system is considered to illustrate the effect of its response to HIV infection, i.e. on viral growth and on T-cell dynamics. Read More

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http://dx.doi.org/10.1007/s10441-018-9340-0DOI Listing
December 2018

From Biological Determination to Entangled Causation.

Acta Biotheor 2019 Mar 4;67(1):19-46. Epub 2018 Sep 4.

Laboratoire ERRAPHIS, PhSciVi, Université Toulouse Jean Jaurès, Maison de la Recherche 5 allée Antonio-Machado, 31058, Toulouse Cedex 9, France.

Biologists and philosophers often use the language of determination in order to describe the nature of developmental phenomena. Accounts in terms of determination have often been reductionist. One common idea is that DNA is supposed to play a special explanatory role in developmental explanations, namely, that DNA is a developmental determinant. Read More

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http://dx.doi.org/10.1007/s10441-018-9339-6DOI Listing

Design Methodologies and the Limits of the Engineering-Dominated Conception of Synthetic Biology.

Authors:
Tero Ijäs

Acta Biotheor 2019 Mar 18;67(1):1-18. Epub 2018 Aug 18.

Practical Philosophy, University of Helsinki, Unioninkatu 40, P.O. Box 24, 00014, Helsinki, Finland.

Synthetic biology is described as a new field of biotechnology that models itself on engineering sciences. However, this view of synthetic biology as an engineering field has received criticism, and both biologists and philosophers have argued for a more nuanced and heterogeneous understanding of the field. This paper elaborates the heterogeneity of synthetic biology by clarifying the role of design and the variability of design methodologies in synthetic biology. Read More

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http://dx.doi.org/10.1007/s10441-018-9338-7DOI Listing
March 2019
3 Reads

Proceedings of the First Vietnamese-French Joint Conference on Applications of Mathematics to Ecology, Bio-economics, Epidemiology and Health Care: Hanoi and Tuanchau, Vietnam, December 12-15, 2016.

Acta Biotheor 2018 Dec 10;66(4):255-256. Epub 2018 Aug 10.

IRD, Sorbonne Universités, UPMC Univ Paris 06, Unité Mixte Internationale de Modélisation Mathématique et Informatique des Systèmes Complexes (UMMISCO), 32 Avenue Henri Varagnat, 93143, Bondy Cedex, France.

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http://dx.doi.org/10.1007/s10441-018-9337-8DOI Listing
December 2018
6 Reads

Mathematical Assessment of the Role of Early Latent Infections and Targeted Control Strategies on Syphilis Transmission Dynamics.

Acta Biotheor 2019 Mar 3;67(1):47-84. Epub 2018 Jul 3.

School of Mathematical and Statistical Sciences, Arizona State University, Arizona, USA.

A new multi-stage deterministic model for the transmission dynamics of syphilis, which incorporates disease transmission by individuals in the early latent stage of syphilis infection and the reversions of early latent syphilis to the primary and secondary stages, is formulated and rigorously analysed. The model is used to assess the population-level impact of preventive (condom use) and therapeutic measures (treatment using antibiotics) against the spread of the disease in a community. It is shown that the disease-free equilibrium of the model is globally-asymptotically stable whenever the associated control reproduction number (denoted by [Formula: see text]) is less than unity. Read More

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http://dx.doi.org/10.1007/s10441-018-9336-9DOI Listing

Study of the Population Dynamics of Busseola fusca, Maize Pest.

Acta Biotheor 2018 Dec 14;66(4):379-397. Epub 2018 Jun 14.

Laboratory of Mathematics, Department of Mathematics and Computer Science, Faculty of Science, University of Douala, PO Box 24157, Douala, Cameroon.

Busseola fusca is a maize and sorghum pest that can cause significant damage to both crops. Given that maize is one of the main cereals grown in the worldwide, this pest is a major challenge for maize production and therefore for the economies of several countries . In this paper , based on the life cycle of B. Read More

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http://dx.doi.org/10.1007/s10441-018-9335-xDOI Listing
December 2018
15 Reads

Correction to: Graphical Representation and Similarity Analysis of DNA Sequences Based on Trigonometric Functions.

Acta Biotheor 2018 09;66(3):251-253

School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China.

In the original publication of the article, the y axis labels present in Figs. 1a and 2a are incorrect. The correct Figs. Read More

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http://dx.doi.org/10.1007/s10441-018-9334-yDOI Listing
September 2018

An Inverse Problem: Trappers Drove Hares to Eat Lynx.

Authors:
Bo Deng

Acta Biotheor 2018 Sep 30;66(3):213-242. Epub 2018 May 30.

Mathematics and Science College, Shanghai Normal University, Shanghai, 200234, China.

The Canadian lynx and snowshoe hare pelt data by the Hudson Bay Company did not fit the classical predator-prey theory. Rather than following the peak density of the hare, that of the lynx leads it, creating the hares-eat-lynx (HEL) paradox. Although trappers were suspected to play a role, no mathematical model has ever demonstrated the HEL effect. Read More

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http://dx.doi.org/10.1007/s10441-018-9333-zDOI Listing
September 2018
1 Read

Permanence and Extinction of a Diffusive Predator-Prey Model with Robin Boundary Conditions.

Acta Biotheor 2018 Dec 28;66(4):367-378. Epub 2018 May 28.

Department of Mathematics, Faculty of Sciences, University of Tlemcen, B.P. 119, 13000, Tlemcen, Algeria.

The main concern of this paper is to study the dynamic of a predator-prey system with diffusion. It incorporates the Holling-type-II and a modified Leslie-Gower functional responses under Robin boundary conditions. More concretely, we study the dissipativeness of the system by using the comparison principle, and we derive a criteria for permanence and for predator extinction. Read More

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http://dx.doi.org/10.1007/s10441-018-9332-0DOI Listing
December 2018

Descriptive Modeling of the Dynamical Systems and Determination of Feedback Homeostasis at Different Levels of Life Organization.

Acta Biotheor 2018 Sep 24;66(3):177-199. Epub 2018 May 24.

Kharkiv National University of Radio Electronics, Nauky ave., 14, Kharkiv, 61166, Ukraine.

The state-of-art research in the field of life's organization confronts the need to investigate a number of interacting components, their properties and conditions of sustainable behaviour within a natural system. In biology, ecology and life sciences, the performance of such stable system is usually related to homeostasis, a property of the system to actively regulate its state within a certain allowable limits. In our previous work, we proposed a deterministic model for systems' homeostasis. Read More

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http://dx.doi.org/10.1007/s10441-018-9321-3DOI Listing
September 2018

Importance of Initial Concentration of Factor VIII in a Mechanistic Model of In Vitro Coagulation.

Authors:
M Susree M Anand

Acta Biotheor 2018 Sep 14;66(3):201-212. Epub 2018 May 14.

Department of Chemical Engineering, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India.

This computational study generates a hypothesis for the coagulation protein whose initial concentration greatly influences the course of coagulation. Many clinical malignancies of blood coagulation arise due to abnormal initial concentrations of coagulation factors. Sensitivity analysis of mechanistic models of blood coagulation is a convenient method to assess the effect of such abnormalities. Read More

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http://dx.doi.org/10.1007/s10441-018-9329-8DOI Listing
September 2018

Natural Selection and Drift as Individual-Level Causes of Evolution.

Authors:
Pierrick Bourrat

Acta Biotheor 2018 Sep 14;66(3):159-176. Epub 2018 May 14.

Department of Philosophy, Macquarie University, North Ryde, NSW, 2109, Australia.

In this paper I critically evaluate Reisman and Forber's (Philos Sci 72(5):1113-1123, 2005) arguments that drift and natural selection are population-level causes of evolution based on what they call the manipulation condition. Although I agree that this condition is an important step for identifying causes for evolutionary change, it is insufficient. Following Woodward, I argue that the invariance of a relationship is another crucial parameter to take into consideration for causal explanations. Read More

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http://dx.doi.org/10.1007/s10441-018-9331-1DOI Listing
September 2018

Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why.

Acta Biotheor 2018 Dec 9;66(4):345-365. Epub 2018 May 9.

INSERM and Université Paris 11 Unit 935, Villejuif, France.

Systems biology is today such a widespread discipline that it becomes difficult to propose a clear definition of what it really is. For some, it remains restricted to the genomic field. For many, it designates the integrated approach or the corpus of computational methods employed to handle the vast amount of biological or medical data and investigate the complexity of the living. Read More

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http://dx.doi.org/10.1007/s10441-018-9330-2DOI Listing
December 2018

Theoretical Assessment of the Impact of Climatic Factors in a Vibrio Cholerae Model.

Acta Biotheor 2018 Dec 4;66(4):279-291. Epub 2018 May 4.

Department of Mathematics and Computer Science, Faculty of Science, University of Ngaoundere, PO Box 454, Ngaoundere, Cameroon.

A mathematical model for Vibrio Cholerae (V. Cholerae) in a closed environment is considered, with the aim of investigating the impact of climatic factors which exerts a direct influence on the bacterial metabolism and on the bacterial reservoir capacity. We first propose a V. Read More

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http://dx.doi.org/10.1007/s10441-018-9322-2DOI Listing
December 2018

The Origin of Species by Means of Mathematical Modelling.

Acta Biotheor 2018 Dec 30;66(4):333-344. Epub 2018 Apr 30.

Institut Camille Jordan, UMR 5208 CNRS, University Lyon 1, 69622, Villeurbanne, France.

Darwin described biological species as groups of morphologically similar individuals. These groups of individuals can split into several subgroups due to natural selection, resulting in the emergence of new species. Some species can stay stable without the appearance of a new species, some others can disappear or evolve. Read More

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http://dx.doi.org/10.1007/s10441-018-9328-9DOI Listing
December 2018
2 Reads

Drug Repositioning by Integrating Known Disease-Gene and Drug-Target Associations in a Semi-supervised Learning Model.

Acta Biotheor 2018 Dec 26;66(4):315-331. Epub 2018 Apr 26.

School of Computer Science and Engineering, Thuyloi University, 175 Tay Son, Dong Da, Hanoi, Vietnam.

Computational drug repositioning has been proven as a promising and efficient strategy for discovering new uses from existing drugs. To achieve this goal, a number of computational methods have been proposed, which are based on different data sources of drugs and diseases. These methods approach the problem using either machine learning- or network-based models with an assumption that similar drugs can be used for similar diseases to identify new indications of drugs. Read More

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http://dx.doi.org/10.1007/s10441-018-9325-zDOI Listing
December 2018

Mathematical Basis of Predicting Dominant Function in Protein Sequences by a Generic HMM-ANN Algorithm.

Authors:
Siddhartha Kundu

Acta Biotheor 2018 Jun 26;66(2):135-148. Epub 2018 Apr 26.

Department of Biochemistry, Dr. Baba Saheb Ambedkar Medical College and Hospital, Government of NCT of Delhi, Sector - 6, Rohini, Delhi, 110085, India.

The accurate annotation of an unknown protein sequence depends on extant data of template sequences. This could be empirical or sets of reference sequences, and provides an exhaustive pool of probable functions. Individual methods of predicting dominant function possess shortcomings such as varying degrees of inter-sequence redundancy, arbitrary domain inclusion thresholds, heterogeneous parameterization protocols, and ill-conditioned input channels. Read More

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http://dx.doi.org/10.1007/s10441-018-9327-xDOI Listing

Adaptive Control Based Harvesting Strategy for a Predator-Prey Dynamical System.

Acta Biotheor 2018 Dec 23;66(4):293-313. Epub 2018 Apr 23.

Computational and Data Sciences, IISc, Bangalore, 560012, India.

This paper deals with designing a harvesting control strategy for a predator-prey dynamical system, with parametric uncertainties and exogenous disturbances. A feedback control law for the harvesting rate of the predator is formulated such that the population dynamics is asymptotically stabilized at a positive operating point, while maintaining a positive, steady state harvesting rate. The hierarchical block strict feedback structure of the dynamics is exploited in designing a backstepping control law, based on Lyapunov theory. Read More

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http://dx.doi.org/10.1007/s10441-018-9323-1DOI Listing
December 2018

Graphical Representation and Similarity Analysis of DNA Sequences Based on Trigonometric Functions.

Acta Biotheor 2018 Jun 19;66(2):113-133. Epub 2018 Apr 19.

School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China.

In this paper, we propose two four-base related 2D curves of DNA primary sequences (termed as F-B curves) and their corresponding single-base related 2D curves (termed as A-related, G-related, T-related and C-related curves). The constructions of these graphical curves are based on the assignments of individual base to four different sinusoidal (or tangent) functions; then by connecting all these points on these four sinusoidal (tangent) functions, we can get the F-B curves; similarly, by connecting the points on each of the four sinusoidal (tangent) functions, we get the single-base related 2D curves. The proposed 2D curves are all strictly non degenerate. Read More

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http://dx.doi.org/10.1007/s10441-018-9324-0DOI Listing
June 2018
1 Read

Culture and the Trajectories of Developmental Pathology: Insights from Control and Information Theories.

Authors:
Rodrick Wallace

Acta Biotheor 2018 Jun 3;66(2):79-112. Epub 2018 Apr 3.

Division of Epidemiology, The New York State Psychiatric Institute, New York, USA.

Cognition in living entities-and their social groupings or institutional artifacts-is necessarily as complicated as their embedding environments, which, for humans, includes a particularly rich cultural milieu. The asymptotic limit theorems of information and control theories permit construction of a new class of empirical 'regression-like' statistical models for cognitive developmental processes, their dynamics, and modes of dysfunction. Such models may, as have their simpler analogs, prove useful in the study and re-mediation of cognitive failure at and across the scales and levels of organization that constitute and drive the phenomena of life. Read More

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http://dx.doi.org/10.1007/s10441-018-9320-4DOI Listing
June 2018
2 Reads

Quaternion-Based Texture Analysis of Multiband Satellite Images: Application to the Estimation of Aboveground Biomass in the East Region of Cameroon.

Acta Biotheor 2018 Mar 21;66(1):17-60. Epub 2018 Mar 21.

UMMISCO, SAM Team, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon.

Within the last decade, several approaches using quaternion numbers to handle and model multiband images in a holistic manner were introduced. The quaternion Fourier transform can be efficiently used to model texture in multidimensional data such as color images. For practical application, multispectral satellite data appear as a primary source for measuring past trends and monitoring changes in forest carbon stocks. Read More

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http://dx.doi.org/10.1007/s10441-018-9317-zDOI Listing

A 3D Individual-Based Model to Study Effects of Chemotaxis, Competition and Diffusion on the Motile-Phytoplankton Aggregation.

Acta Biotheor 2018 Dec 15;66(4):257-278. Epub 2018 Mar 15.

IRD, UMI 209, UMMISCO, Bondy, France.

In this paper, we develop a 3D-individual-based model (IBM) to understand effect of various small-scale mechanisms in phytoplankton cells, on the cellular aggregation process. These mechanisms are: spatial interactions between cells due to their chemosensory abilities (chemotaxis), a molecular diffusion and a demographical process. The latter is considered as a branching process with a density-dependent death rate to take into account the local competition on resources. Read More

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http://dx.doi.org/10.1007/s10441-018-9318-yDOI Listing
December 2018
1 Read

Prediction of Apoptosis Protein's Subcellular Localization by Fusing Two Different Descriptors Based on Evolutionary Information.

Acta Biotheor 2018 Mar 12;66(1):61-78. Epub 2018 Mar 12.

School of Mathematics and Statistics, Xidian University, Xi'an, 710071, People's Republic of China.

The apoptosis protein has a central role in the development and the homeostasis of an organism. Obtaining information about the subcellular localization of apoptosis protein is very helpful to understand the apoptosis mechanism and the function of this protein. Prediction of apoptosis protein's subcellular localization is a challenging task, and currently the existing feature extraction methods mainly rely on the protein's primary sequence. Read More

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http://dx.doi.org/10.1007/s10441-018-9319-xDOI Listing
March 2018
2 Reads

R: Host Longevity Matters.

Acta Biotheor 2018 Mar 19;66(1):1-16. Epub 2018 Feb 19.

Biometris, Department of Mathematical and Statistical Methods, Wageningen University, Wageningen, The Netherlands.

The basic reproduction ratio, R, is a fundamental concept in epidemiology. It is defined as the total number of secondary infections brought on by a single primary infection, in a totally susceptible population. The value of R indicates whether a starting epidemic reaches a considerable part of the population and causes a lot of damage, or whether it remains restricted to a relatively small number of individuals. Read More

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http://dx.doi.org/10.1007/s10441-018-9315-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874282PMC

A Model of Isotope Separation in Plants.

Acta Biotheor 2017 Dec 24;65(4):271-284. Epub 2017 Nov 24.

Ural Federal University, Yekaterinburg, Russia.

A model representing isotope separation during water evaporation in plants was constructed. The model accounts for substance diffusion, convective transfer and evaporation from the surface of the leaves. The dependence of the system's separation and enrichment coefficients on various parameters (liquid velocity, diffusion coefficient, and potential barriers for molecules and their thermal velocities) was determined. Read More

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http://dx.doi.org/10.1007/s10441-017-9314-7DOI Listing
December 2017

On Scott-Phillips' General Account of Communication.

Authors:
Ronald J Planer

Acta Biotheor 2017 Dec 8;65(4):253-270. Epub 2017 Aug 8.

School of Philosophy, The Australian National University, Canberra, Australia.

The purpose of this paper is to critically engage with a recent attempt by Thom Scott-Phillips to offer a general account of communication. As a general account, it is intended to apply equally well to both non-human and human interactions which are prima facie communicative in character. However, so far, Scott-Phillips has provided little detail regarding how his account is supposed to apply to the latter set of cases. Read More

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http://dx.doi.org/10.1007/s10441-017-9313-8DOI Listing
December 2017

Microscale Gaseous Slip Flow in the Insect Trachea and Tracheoles.

Acta Biotheor 2017 Sep 11;65(3):211-231. Epub 2017 Jul 11.

School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Private Bag 3 Wits, Johannesburg, 2050, South Africa.

An analytical investigation into compressible gas flow with slight rarefactions through the insect trachea and tracheoles during the closed spiracle phase is undertaken, and a complete set of asymptotic analytical solutions is presented. We first obtain estimates of the Reynolds and Mach numbers at the channel terminal ends where the tracheoles directly deliver respiratory gases to the cells, by comparing the magnitude of the different forces in the compressible gas flow. The 2D Navier-Stokes equations with a slip boundary condition are used to investigate compressibility and rarefied effects in the trachea and tracheoles. Read More

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http://link.springer.com/10.1007/s10441-017-9312-9
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http://dx.doi.org/10.1007/s10441-017-9312-9DOI Listing
September 2017
3 Reads

What do Biologists Make of the Species Problem?

Acta Biotheor 2017 Sep 13;65(3):179-209. Epub 2017 May 13.

Department of Biology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000, Zagreb, Croatia.

The concept of species is one of the core concepts in biology and one of the cornerstones of evolutionary biology, yet it is rife with conceptual problems. Philosophers of biology have been discussing the concept of species for decades, and in doing so they sometimes appeal to the views of biologists. However, their statements as to what biologists think are seldom supported by empirical data. Read More

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http://dx.doi.org/10.1007/s10441-017-9311-xDOI Listing
September 2017
1 Read

Establishing a Framework for a Natural Area Taxonomy.

Acta Biotheor 2017 Sep 10;65(3):167-177. Epub 2017 May 10.

, Private Bag, Kaukapakapa, 0843, New Zealand.

The identification of areas of endemism is essential in building an area classification, but plays little role in how natural areas are discovered. Rather area monophyly, derived from cladistics, is essential in the discovery of natural area classifications or area taxonomy. We propose Area Taxonomy to be a new sub-discipline of historical biogeography, one that can be revised and debated, and which has its own area nomenclature. Read More

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http://dx.doi.org/10.1007/s10441-017-9310-yDOI Listing
September 2017

Asymptotic Behavior of a Chemostat Model with Constant Recycle Sludge Concentration.

Acta Biotheor 2017 Sep 4;65(3):233-252. Epub 2017 May 4.

Laboratoire Systèmes Dynamiques et Applications, Tlemcen University, BP 119, 13000, Tlemcen, Algeria.

In this work, we study a several species aerobic chemostat model with constant recycle sludge concentration in continuous culture. We reduce the number of parameters by considering a dimensionless model. First, the existence of a global positive uniform attractor for the model with different removal rates is proved using the theory of dissipative dynamical systems. Read More

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http://dx.doi.org/10.1007/s10441-017-9309-4DOI Listing
September 2017
52 Reads

Skewed Exposure to Environmental Antigens Complements Hygiene Hypothesis in Explaining the Rise of Allergy.

Acta Biotheor 2017 Jun 24;65(2):117-134. Epub 2017 Mar 24.

Genomics Research Center, Academia Sinica, Taipei, 11529, Taiwan.

The Hygiene Hypothesis has been recognized as an important cornerstone to explain the sudden increase in the prevalence of asthma and allergic diseases in modernized culture. The recent epidemic of allergic diseases is in contrast with the gradual implementation of Homo sapiens sapiens to the present-day forms of civilization. This civilization forms a gradual process with cumulative effects on the human immune system, which co-developed with parasitic and commensal Helminths. Read More

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http://dx.doi.org/10.1007/s10441-017-9306-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418306PMC
June 2017
30 Reads

Stability of a Stochastic Model of an SIR Epidemic with Vaccination.

Authors:
P J Witbooi

Acta Biotheor 2017 Jun 21;65(2):151-165. Epub 2017 Mar 21.

Department of Mathematics and Applied Mathematics, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa.

We prove almost sure exponential stability for the disease-free equilibrium of a stochastic differential equations model of an SIR epidemic with vaccination. The model allows for vertical transmission. The stochastic perturbation is associated with the force of infection and is such that the total population size remains constant in time. Read More

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http://dx.doi.org/10.1007/s10441-017-9308-5DOI Listing

External Noise and External Signal Induced Transition of Gene Switch and Coherence Resonance in the Genetic Regulatory System.

Acta Biotheor 2017 Jun 17;65(2):135-150. Epub 2017 Mar 17.

College of Chemistry and Material Science, Guangxi Teachers Education University, Nanning, 530001, China.

The transition of gene switch induced by external noises (multiplicative external noise and additive external noise) and external signals is investigated in the genetic regulatory system. Results show that the state-to-state transition of gene switch as well as resonant behaviors, such as the explicit coherence resonance (ECR), implicit coherence resonance (ICR) and control parameter coherence biresonance (CPCBR), can appear when noises are injected into the genetic regulatory system. The ECR is increased with the increase of the control parameter value when starting from the supercritical Hopf bifurcation parameter point, and there exists a critical control parameter value for the occurrence of ECR. Read More

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http://link.springer.com/10.1007/s10441-017-9307-6
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http://dx.doi.org/10.1007/s10441-017-9307-6DOI Listing
June 2017
3 Reads

Mapping Biological Transmission: An Empirical, Dynamical, and Evolutionary Approach.

Acta Biotheor 2017 Jun 14;65(2):97-115. Epub 2017 Feb 14.

Atelier des Jours à Venir, 97 allée Théodore Monod, 64210, Bidart, France.

The current debate over extending inheritance and its evolutionary impact has focused on adding new categories of non-genetic factors to the classical transmission of DNA, and on trying to redefine inheritance. Transmitted factors have been mainly characterized by their directions of transmission (vertical, horizontal, or both) and the way they store variations. In this paper, we leave aside the issue of defining inheritance. Read More

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http://dx.doi.org/10.1007/s10441-017-9305-8DOI Listing

Dual Causality and the Autonomy of Biology.

Authors:
Walter J Bock

Acta Biotheor 2017 Mar 2;65(1):63-79. Epub 2017 Jan 2.

Department of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, Mail Box 2428, New York, NY, 10027, USA.

Ernst Mayr's concept of dual causality in biology with the two forms of causes (proximate and ultimate) continues to provide an essential foundation for the philosophy of biology. They are equivalent to functional (=proximate) and evolutionary (=ultimate) causes with both required for full biological explanations. The natural sciences can be classified into nomological, historical nomological and historical dual causality, the last including only biology. Read More

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http://dx.doi.org/10.1007/s10441-016-9303-2DOI Listing
March 2017
3 Reads

On the Role of Imitation on Adolescence Methamphetamine Abuse Dynamics.

Acta Biotheor 2017 Mar 18;65(1):37-61. Epub 2016 Dec 18.

Department of Mathematics, University of Zimbabwe, Box MP 167, Mount Pleasant, Harare, Zimbabwe.

Adolescence methamphetamine use is an issue of considerable concern due to its correlation with later delinquency, divorce, unemployment and health problems. Understanding how adolescents initiate methamphetamine abuse is important in developing effective prevention programs. We formulate a mathematical model for the spread of methamphetamine abuse using nonlinear ordinary differential equations. Read More

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http://dx.doi.org/10.1007/s10441-016-9302-3DOI Listing
March 2017
9 Reads

Discrete Mesh Approach in Morphogenesis Modelling: the Example of Gastrulation.

Acta Biotheor 2016 Dec 16;64(4):427-446. Epub 2016 Nov 16.

TIMC-IMAG, Faculty of Medicine of Grenoble, University J. Fourier, 38700, La Tronche, France.

Morphogenesis is a general concept in biology including all the processes which generate tissue shapes and cellular organizations in a living organism. Many hybrid formalizations (i.e. Read More

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http://dx.doi.org/10.1007/s10441-016-9301-4DOI Listing
December 2016
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Wound Healing and Scale Modelling in Zebrafish.

Acta Biotheor 2016 Dec 11;64(4):343-358. Epub 2016 Nov 11.

Institut Camille Jordan, UMR 5208 CNRS, University Lyon 1, 69622, Villeurbanne, France.

We propose to study the wound healing in Zebrafish by using firstly a differential approach for modelling morphogens diffusion and cell chemotactic motion, and secondly a hybrid model of tissue regeneration, where cells are considered as individual objects and molecular concentrations are described by partial differential equations. Read More

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http://dx.doi.org/10.1007/s10441-016-9298-8DOI Listing
December 2016

Interactions Between the Cross-Shore Structure of Small Pelagic Fish Population, Offshore Industrial Fisheries and Near Shore Artisanal Fisheries: A Mathematical Approach.

Acta Biotheor 2016 Dec 26;64(4):479-493. Epub 2016 Oct 26.

Institut de Recherche pour le Développement (IRD), UMR 195 Lemar, Co ISRA-CRODT, B.P. 1386, Hann, Dakar, Senegal.

This work presents a mathematical model describing the interactions between the cross-shore structure of small pelagic fish population an their exploitation by coastal and offshore fisheries. The complete model is a system of seven ODE's governing three stocks of small pelagic fish population moving and growing between three zones. Two types of fishing fleets are inter-acting with the fish population, industrial boats, constrained to offshore area, and artisanal boats, operating from the shore. Read More

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http://link.springer.com/10.1007/s10441-016-9299-7
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http://dx.doi.org/10.1007/s10441-016-9299-7DOI Listing
December 2016
7 Reads

Preface.

Acta Biotheor 2016 Dec 21;64(4):309-310. Epub 2016 Oct 21.

Université de Poitiers, Laboratoire de Mathématiques et Applications, UMR CNRS 7348, SP2MI, Futuroscope, France.

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http://dx.doi.org/10.1007/s10441-016-9300-5DOI Listing
December 2016
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Basin of Attraction of Solutions with Pattern Formation in Slow-Fast Reaction-Diffusion Systems.

Acta Biotheor 2016 Dec 21;64(4):311-325. Epub 2016 Oct 21.

UNIHAVRE, LMAH, FR-CNRS-3335, ISCN, Normandie Univ, 76600, Le Havre, France.

This article is devoted to the characterization of the basin of attraction of pattern solutions for some slow-fast reaction-diffusion systems with a symmetric property and an underlying oscillatory reaction part. We characterize some subsets of initial conditions that prevent the dynamical system to evolve asymptotically toward solutions which are homogeneous in space. We also perform numerical simulations that illustrate theoretical results and give rise to symmetric and non-symmetric pattern solutions. Read More

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http://dx.doi.org/10.1007/s10441-016-9294-zDOI Listing
December 2016

Can Fishing Pressure Invert the Outcome of Interspecific Competition? The Case of the Thiof and of the Octopus Along the Senegalese Coast.

Acta Biotheor 2016 Dec 21;64(4):519-536. Epub 2016 Oct 21.

Institut de Recherche pour le Développement (IRD), UMR 248 MARBEC, LABEP-AO (IRD-IFAN), BP 1386, Dakar, Senegal.

We present a mathematical model of two competing marine species that are harvested. We consider three models according to different levels of complexity, without and with species refuge and density-independent and density-dependent species movement between fishing area and refuge. We particularly study the effects of the fishing pressure on the outcome of the competition. Read More

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http://dx.doi.org/10.1007/s10441-016-9292-1DOI Listing
December 2016
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Effects of Behavioural Strategy on the Exploitative Competition Dynamics.

Acta Biotheor 2016 Dec 21;64(4):495-517. Epub 2016 Oct 21.

School of Applied Mathematics and Informatics, Hanoi University of Science and Technology, No 1, Dai Co Viet Street, Hanoi, Vietnam.

We investigate a system of two species exploiting a common resource. We consider both abiotic (i.e. Read More

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http://dx.doi.org/10.1007/s10441-016-9297-9DOI Listing
December 2016

A Greedy Algorithm for Brain MRI's Registration.

Acta Biotheor 2016 Dec 19;64(4):359-374. Epub 2016 Oct 19.

LMA, Université de Poitiers, Poitiers, France.

This document presents a non-rigid registration algorithm for the use of brain magnetic resonance (MR) images comparison. More precisely, we want to compare pre-operative and post-operative MR images in order to assess the deformation due to a surgical removal. The proposed algorithm has been studied in Chesseboeuf et al. Read More

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http://dx.doi.org/10.1007/s10441-016-9296-xDOI Listing
December 2016

Recursive Model Identification for the Evaluation of Baroreflex Sensitivity.

Acta Biotheor 2016 Dec 18;64(4):469-478. Epub 2016 Oct 18.

INSERM, U1099, Rennes, 35000, France.

A method for the recursive identification of physiological models of the cardiovascular baroreflex is proposed and applied to the time-varying analysis of vagal and sympathetic activities. The proposed method was evaluated with data from five newborn lambs, which were acquired during injection of vasodilator and vasoconstrictors and the results show a close match between experimental and simulated signals. The model-based estimation of vagal and sympathetic contributions were consistent with physiological knowledge and the obtained estimators of vagal and sympathetic activities were compared to traditional markers associated with baroreflex sensitivity. Read More

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http://dx.doi.org/10.1007/s10441-016-9295-yDOI Listing
December 2016
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A Mathematical Model for Alternation of Polygamy and Parthenogenesis: Stability Versus Efficiency and Analogy with Parasitism.

Acta Biotheor 2016 Dec 13;64(4):537-552. Epub 2016 Oct 13.

Laboratoire Jacques-louis Lions, UPMC Univ Paris 06 and CNRS, UMR 7598, Sorbonne Universités, 75005, Paris, France.

The present work is a contribution to the understanding of the sempiternal problem of the "burden of factor two" implied by sexual reproduction versus asexual one, as males are energy consumers not contributing to the production of offspring. We construct a deterministic mathematical model in population dynamics where a species enjoys both sexual and parthenogenetic capabilities of reproduction and lives on a limited resource. We then show how polygamy implies instability of a parthenogenetic population with a small number of sexually born males. Read More

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http://dx.doi.org/10.1007/s10441-016-9293-0DOI Listing
December 2016