672,884 results match your criteria Acta Alimentaria[Journal]


Mouthguard use and TMJ injury prevention with different occlusions: A three-dimensional finite element analysis.

Dent Traumatol 2020 May 27. Epub 2020 May 27.

Department of Oral Cell Biology and Functional Anatomy, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and VU UniversityAmsterdam, Amsterdam, The Netherlands.

Background/aims: There is a lack of data regarding the temporomandibular joint's mechanical response during an impact to the orofacial region. The aim of this study was to analyze the biomechanical effects of wearing a mouthguard (MG) on the impact response of the mandibular condyle and articular disc according to the type of occlusion. The hypothesis was that the MG would minimize the effect in those structures, regardless of the occlusion type. Read More

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http://dx.doi.org/10.1111/edt.12577DOI Listing

Influence of maternal region of birth on neonatal outcomes of babies born small.

Acta Paediatr 2020 May 27. Epub 2020 May 27.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.

Aim: To compare neonatal outcomes of Small for Gestational Age (SGA) infants born to South Asian (SA)-born women, and Australia New Zealand (ANZ)-born women.

Methods: Retrospective cohort study at a hospital network in Australia. Maternal and neonatal data was collected for infants born SGA between 2013-2017 to SA or ANZ-born women. Read More

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http://dx.doi.org/10.1111/apa.15375DOI Listing

Delayed Diagnosis of Pediatric Appendicitis during the COVID-19 Pandemic.

Acta Paediatr 2020 May 27. Epub 2020 May 27.

Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Aim: To present seven pediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic.

Methods: Cases were collected from three pediatric surgical wards. Comparison between complicated appendicitis rates in the COVID-19 era and similar period in previous year was performed. Read More

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http://dx.doi.org/10.1111/apa.15376DOI Listing

Acquired hemophilia A revealed by spontaneous bleeding in an 80-year-old man: a marginal diagnosis?

Acta Clin Belg 2020 May 27:1-3. Epub 2020 May 27.

Department of Hematology, Hôpital Erasme, Université Libre De Bruxelles , Brussels, Belgium.

This case report illustrates the difficulty associated with diagnosing acquired hemophilia A by reviewing the case of an 80-year-old man admitted to the hospital for anemia. A prolonged activated partial thromboplastin time (aPTT) was not noticed until the patient developed a severe hemorrhagic syndrome. Read More

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http://dx.doi.org/10.1080/17843286.2020.1768735DOI Listing

[COVID-19 and The Invisible Damage: The Role of The Family Physician].

Authors:
Maria Gouveia

Acta Med Port 2020 May 27. Epub 2020 May 27.

Unidade de Saúde Familiar de São Julião. Agrupamento de Centros de Saúde de Lisboa Ocidental e Oeiras. Lisboa. Portugal.

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http://dx.doi.org/10.20344/amp.14157DOI Listing

Desloratadine and loratadine stand out among common H-antihistamines for association with improved breast cancer survival.

Acta Oncol 2020 May 27:1-7. Epub 2020 May 27.

Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.

As tumors maintain an inflammatory microenvironment, anti-inflammatory medication can be useful in cancer therapy. We have previously shown an association with improved survival in melanoma for use of the H-antihistamines desloratadine and loratadine, and here we examine use of H-antihistamines and breast cancer mortality. We investigated use of the six major H-antihistamines (cetirizine, clemastine, desloratadine, ebastine, fexofenadine and loratadine) and breast cancer-specific and overall mortality in a nation-wide register-based study of all 61,627 Swedish women diagnosed with breast cancer 2006-2013. Read More

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http://dx.doi.org/10.1080/0284186X.2020.1769185DOI Listing

Efficiency of chemical versus mechanical disruption methods of DNA extraction for the identification of oral Gram-positive and Gram-negative bacteria.

J Int Med Res 2020 May;48(5):300060520925594

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objective: Clinical diagnostics often requires the detection of multiple bacterial species in limited clinical samples with a single DNA extraction method. This study aimed to compare the bacterial DNA extraction efficiency of two lysis methods automated with the MagNA-Pure LC instrument. The samples included five oral bacterial species (three Gram-positive and two Gram-negative) with or without human saliva background. Read More

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http://dx.doi.org/10.1177/0300060520925594DOI Listing

TBK1, a central kinase in innate immune sensing of nucleic acids and beyond.

Acta Biochim Biophys Sin (Shanghai) 2020 May 27. Epub 2020 May 27.

MOE Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.

Sensing of intracellular and extracellular environments is one of the fundamental processes of cell. Surveillance of aberrant nucleic acids, derived either from invading pathogens or damaged organelle, is conducted by pattern recognition receptors (PRRs) including RIG-I-like receptors, cyclic GMP-AMP synthase, absent in melanoma 2, and a few members of toll-like receptors. TANK-binding kinase 1 (TBK1), along with its close analogue I-kappa-B kinase epsilon, is a central kinase in innate adaptor complexes linking activation of PRRs to mobilization of transcriptional factors that transcribe proinflammatory cytokines, type I interferon (IFN-α/β), and myriads interferon stimulated genes. Read More

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http://dx.doi.org/10.1093/abbs/gmaa051DOI Listing

High-intensity vessel sign on fluid-attenuated inversion recovery imaging: a novel imaging marker of high-risk carotid stenosis-a MRI and SPECT study.

Acta Neurochir (Wien) 2020 May 26. Epub 2020 May 26.

Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

Background: Measurement of luminal stenosis and determination of plaque instability using MR plaque imaging are effective strategies for evaluating high-risk carotid stenosis. Nevertheless, new methods are required to identify patients with carotid stenosis at risk of future stroke. We aimed to clarify the mechanisms and clinical implications of the hyperintense vessel sign (HVS) as a marker of high-risk carotid stenosis. Read More

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http://dx.doi.org/10.1007/s00701-020-04408-4DOI Listing

Superior accuracy and precision of SEEG electrode insertion with frame-based vs. frameless stereotaxy methods.

Acta Neurochir (Wien) 2020 May 26. Epub 2020 May 26.

Department of Neurosurgery, University of California Davis School of Medicine, 4860 Y St. Suite 3740, Sacramento, 95817, USA.

Background: Stereotactic electroencephalography (SEEG) has largely become the preferred method for intracranial seizure localization in epileptic patients due to its low morbidity and minimally invasive approach. While robotic placement is gaining popularity, many centers continue to use manual frame-based and frameless methods for electrode insertion. However, it is unclear how these methods compare in regard to accuracy, precision, and safety. Read More

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http://dx.doi.org/10.1007/s00701-020-04427-1DOI Listing

Promoted off-on recognition of HO based on the fluorescence of silicon quantum dots assembled two-dimensional PEG-MnO nanosheets hybrid nanoprobe.

Mikrochim Acta 2020 May 26;187(6):347. Epub 2020 May 26.

Guangdong Provincial Engineering Technology Research Center for Optical Agriculture, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

An "off-on" assay system for HO determination was developed based on assembling ultra-bright fluorescent silicon quantum dots (SiQDs) and PEG-MnO nanosheets. Among them, SiQDs acted as fluorometric reporter, which can effectively eliminate the interference of plant pigments under excitation of 365 nm. PEG-MnO nanosheets played dual function of nanoquencher and HO recognizer. Read More

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http://dx.doi.org/10.1007/s00604-020-04276-wDOI Listing

In situ encapsulation of horseradish peroxidase in zeolitic imidazolate framework-8 enables catalyzing luminol reaction under near-neutral conditions for sensitive chemiluminescence determination of cholesterol.

Mikrochim Acta 2020 May 26;187(6):346. Epub 2020 May 26.

Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.

HRP@ZIF-8 nanocomposite was prepared by in situ encapsulation of horseradish peroxidase (HRP) in the frame of zeolitic imidazolate framework-8 (ZIF-8) with a simple one-pot method. The HRP@ZIF-8 nanocomposite displays outstanding thermal stability and efficiently catalyzes the chemiluminescence (CL) reaction of luminol with hydrogen peroxide (HO) under near-neutral pH condition (pH 7-8). This CL system has a good response to HO with a linear range of 0. Read More

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http://dx.doi.org/10.1007/s00604-020-04313-8DOI Listing

Baicalin prevents LPS-induced activation of TLR4/NF-κB p65 pathway and inflammation in mice via inhibiting the expression of CD14.

Acta Pharmacol Sin 2020 May 26. Epub 2020 May 26.

School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.

Previous studies have shown that baicalin, an active ingredient of the Chinese traditional medicine Huangqin, attenuates LPS-induced inflammation by inhibiting the activation of TLR4/NF-κBp65 pathway, but how it affects this pathway is unknown. It has been shown that CD14 binds directly to LPS and plays an important role in sensitizing the cells to minute quantities of LPS via chaperoning LPS molecules to the TLR4/MD-2 signaling complex. In the present study we investigated the role of CD14 in the anti-inflammatory effects of baicalin in vitro and in vivo. Read More

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http://dx.doi.org/10.1038/s41401-020-0411-9DOI Listing

Blockage of sphingosine-1-phosphate receptor 2 attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice.

Acta Pharmacol Sin 2020 May 26. Epub 2020 May 26.

College of Pharmacy, Pusan National University, Busan, 46241, Republic of Korea.

Sphingosine-1-phosphate (S1P) and its receptors have been implicated in functions of Langerhans cells and atopic dermatitis. In this study, we investigated the roles of S1P receptor type 2 (S1P) in a mouse model of atopic dermatitis, which was induced by topical application of 2,4-dinitrochlorobenzene (DNCB) on ventral skin on D0, followed by repeated DNCB challenge on both ears from D7 to D49. Wild-type mice with atopic dermatitis displayed severe inflammation and mast cell accumulation in ear tissues and elevated IgE levels in serum. Read More

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http://dx.doi.org/10.1038/s41401-020-0412-8DOI Listing

Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.

Acta Pharmacol Sin 2020 May 26. Epub 2020 May 26.

State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism, China Pharmaceutical University, Nanjing, 210009, China.

Programmed cell death (PCD), including apoptosis, apoptotic necrosis, and pyroptosis, is involved in various organ dysfunction syndromes. Recent studies have revealed that a substrate of caspase-3, gasdermin E (GSDME), functions as an effector for pyroptosis; however, few inhibitors have been reported to prevent pyroptosis mediated by GSDME. Here, we developed a class of GSDME-derived inhibitors containing the core structure of DMPD or DMLD. Read More

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http://dx.doi.org/10.1038/s41401-020-0434-2DOI Listing

Application of targeted therapy strategies with nanomedicine delivery for atherosclerosis.

Acta Pharmacol Sin 2020 May 26. Epub 2020 May 26.

Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China.

Atherosclerosis (AS) is the main pathological cause of coronary heart disease (CHD). Current clinical interventions including statin drugs can effectively reduce acute myocardial infarction and stroke to some extent, but residual risk remains high. The current clinical treatment regimens are relatively effective for early atherosclerotic plaques and can even reverse their progression. Read More

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http://dx.doi.org/10.1038/s41401-020-0436-0DOI Listing

Author Correction: Ophiopogonin D maintains Ca homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/ EETs and suppressing ER stress.

Acta Pharmacol Sin 2020 May 26. Epub 2020 May 26.

Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing, 100850, China.

An amendment to this paper has been published and can be accessed via a link at the top of the paper. Read More

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http://dx.doi.org/10.1038/s41401-020-0428-0DOI Listing

Diabetic Striatopathy.

Acta Med Port 2020 May 26. Epub 2020 May 26.

Department of Medicine. Faculty of Medicine. Chulalongkorn University. Bangkok. Excellent Center in Diabetes, Hormone and Metabolism. King Chulalongkorn Memorial Hospital. Thai Red Cross Society. Bangkok. Thailand.

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http://dx.doi.org/10.20344/amp.13111DOI Listing

The use of tear ferning test in cats for evaluation of ocular surface.

Acta Vet Scand 2020 May 26;62(1):23. Epub 2020 May 26.

Department of Agrarian and Environmental Sciences, Santa Cruz State University, Rodovia Jorge Amado, Ilheus, Bahia, 45662-900, Brazil.

Background: The tear film is a trilaminar fluid composed mainly of lipids, electrolytes, proteins and water. It is responsible for lubrication, nutrition and protection against microbial and toxic agents. Disruption of any these components may weaken the ocular surface, making it more susceptible to disease. Read More

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http://dx.doi.org/10.1186/s13028-020-00523-5DOI Listing

Change in Norwegian consumer attitudes towards piglet castration: increased emphasis on animal welfare.

Acta Vet Scand 2020 May 26;62(1):22. Epub 2020 May 26.

Animalia, Norwegian Meat and Poultry Research Centre, Lørenveien 38, 0585, Oslo, Norway.

Background: Male piglets are surgically castrated at a young age primarily to prevent pork meat from being tainted with boar taint, an offensive taste and odor that can be present in uncastrated male pigs. The practice of surgical castration is considered to be both stressful and painful for the piglets, and is therefore under scrutiny due to animal welfare concerns. Rearing of intact males or vaccination against boar taint (immunocastration) are two potential alternatives to surgical castration, but in order to successfully implement either of these alternatives, consumer acceptance of the different methods must be taken into consideration as it will be central for future sales of pork products. Read More

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http://dx.doi.org/10.1186/s13028-020-00522-6DOI Listing

Plasminogen deficiency does not prevent sodium retention in a genetic mouse model of experimental nephrotic syndrome.

Acta Physiol (Oxf) 2020 May 26. Epub 2020 May 26.

Department of Internal Medicine, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, Germany.

Aim: Sodium retention is the hallmark of nephrotic syndrome (NS) and mediated by the proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases. Plasmin is highly abundant in nephrotic urine and has been proposed to be the principal serine protease responsible for ENaC activation in NS. However, a proof of the essential role of plasmin in experimental NS is lacking. Read More

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http://dx.doi.org/10.1111/apha.13512DOI Listing

Primary Synovial Sarcoma of the Thyroid: Challenges in Cytologic Diagnosis and Review of the Literature.

Acta Cytol 2020 May 26:1-9. Epub 2020 May 26.

Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA.

Background: Primary synovial sarcoma (SS) of the thyroid (PSST) is extremely rare. Its differential diagnosis from other neoplasms is essential since it has different management protocols and prognosis.

Case: A 26-year-old man with a 4. Read More

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http://dx.doi.org/10.1159/000507312DOI Listing

COVID-19 and Nasal Cytobrush Cytology.

Acta Cytol 2020 May 26:1-2. Epub 2020 May 26.

Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

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http://dx.doi.org/10.1159/000508768DOI Listing

A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology: The Sydney System.

Acta Cytol 2020 May 26:1-17. Epub 2020 May 26.

Department of Medicine and Surgery, Università degli Studi di Salerno, Fisciano, Salerno, Italy,

Background: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC.

Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. Read More

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http://dx.doi.org/10.1159/000506497DOI Listing

Sequence matters: Combining Prolonged Exposure and EMDR therapy for PTSD.

Psychiatry Res 2020 May 16;290:113032. Epub 2020 May 16.

Research department PSYTREC, Bilthoven, The Netherlands; Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, The Netherlands; School of Health Sciences, Salford University, Manchester, United Kingdom; Institute of Health and Society, University of Worcester, United Kingdom; School of Psychology, Queen's University, Belfast Northern Ireland. Electronic address:

Objective: Investigating the influence of the sequence in which two evidence-based trauma-focused treatments are offered to PTSD-patients.

Methods: PTSD-patients were treated using an intensive eight-day treatment program, combining Prolonged Exposure (PE) and EMDR therapy. Forty-four patients received a PE session in the morning and an EMDR session in the afternoon, while 62 patients received the reversed sequence (EMDR followed by PE). Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113032DOI Listing

Functional BOD-Ad-Cmyc@BSA complex nanosensor for Cu(II) and the detection of live E. coli.

Spectrochim Acta A Mol Biomol Spectrosc 2020 May 14;239:118483. Epub 2020 May 14.

School of the Environment and Safety Engineering, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jingkou District, Xuefu Road, 212013, People's Republic of China. Electronic address:

Escherichia coli (E. coli) is abundantly present in nature. It is generally harmless to humans but some strains have been deemed very dangerous. Read More

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http://dx.doi.org/10.1016/j.saa.2020.118483DOI Listing

Copper mediates mitochondrial biogenesis in retinal pigment epithelial cells.

Biochim Biophys Acta Mol Basis Dis 2020 May 23:165843. Epub 2020 May 23.

R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address:

Age related macular degeneration (AMD) is a multifactorial disease with genetic, biochemical and environmental risk factors. We observed a significant increase in copper levels in choroid-RPE from donor eyeballs with AMD. Adult retinal pigment epithelial cells (ARPE19 cells) exposed to copper in-vitro showed a 2-fold increase in copper influx transporter CTR1 and copper uptake at 50 μM concentration. Read More

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http://dx.doi.org/10.1016/j.bbadis.2020.165843DOI Listing

Self-assembling Prodrug Nanotherapeutics for Synergistic Tumor Targeted Drug Delivery.

Acta Biomater 2020 May 23. Epub 2020 May 23.

Skaggs Pharmaceutical Sciences Center, Department of Pharmacology & Toxicology, College of Pharmacy, The University of Arizona, Tucson, Arizona, 85721, United States; NCI-designated University of Arizona Comprehensive Cancer Center, Tucson, Arizona, 85721, United States; Southwest Environmental Health Sciences Center, The University of Arizona, Tucson, 85721, United States; BIO5 Institute, The University of Arizona, Tucson, Arizona, 85721, United States. Electronic address:

Self-assembling prodrugs represents a robust and effective nanotherapeutic approach for delivering poorly soluble anticancer drugs. With numerous intrinsic advantages, self-assembling prodrugs possess the maximum drug loading capacity, controlled drug release kinetics, prolonged blood circulation, and preferential tumor accumulation based on the enhanced permeability and retention (EPR) effect. These prodrug conjugates allow for efficient self-assembly into nanodrugs with the potential of encapsulating other therapeutic agents that have different molecular targets, enabling simultaneous temporal-spatial release of drugs for synergistic antitumor efficacy with reduced systemic side effects. Read More

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http://dx.doi.org/10.1016/j.actbio.2020.05.026DOI Listing

Glycogen synthase kinase-3 signaling in cellular and behavioral responses to psychostimulant drugs.

Biochim Biophys Acta Mol Cell Res 2020 May 23:118746. Epub 2020 May 23.

Center for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA; Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA. Electronic address:

Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase implicated in numerous physiological processes and cellular functions through its ability to regulate the function of many proteins, including transcription factors and structural proteins. GSK-3β has been demonstrated to function as a regulator of multiple behavioral processes induced by drugs of abuse, particularly psychostimulant drugs. In this review, we provide an overview of the regulation of GSK-3β activity produced by psychostimulants, and the role of GSK-3β signaling in psychostimulant-induced behaviors including drug reward, associative learning and memory which play a role in the maintenance of drug-seeking. Read More

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http://dx.doi.org/10.1016/j.bbamcr.2020.118746DOI Listing

How well do laboratories adhere to recommended guidelines for dyslipidaemia management in Europe? The CArdiac MARker Guideline Uptake in Europe (CAMARGUE) Study.

Clin Chim Acta 2020 May 23. Epub 2020 May 23.

Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, Helsinki, Finland.

Background: The CArdiac MARker Guidelines Uptake in Europe Study (CAMARGUE) initiated by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) aims to survey the current use of evidence-based guidelines for dyslipidemia testing in Europe.

Methods: In 2019 a web-based questionnaire was distributed via EFLM National Societies to clinical laboratories in Europe. Questions covered pre-analytics, analytical methods, measurement units, flagging of decision thresholds, and use of decision-enhancing comments. Read More

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http://dx.doi.org/10.1016/j.cca.2020.05.038DOI Listing

An evidence for correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and outcome of COVID-19.

Authors:
Mostafa Saadat

Clin Chim Acta 2020 May 23. Epub 2020 May 23.

Department of Biology, College of Sciences, Shiraz University, Shiraz 71467-13565, Iran.

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http://dx.doi.org/10.1016/j.cca.2020.05.041DOI Listing

Malaria transmission and individual variability of the naturally acquired IgG antibody against the Plasmodium vivax blood-stage antigen in an endemic area in Brazil.

Acta Trop 2020 May 23:105537. Epub 2020 May 23.

Universidade Federal do Pará, Instituto de Ciências Biológicas, CEP: 66075-110, Belém, Pará, Brazil.

Plasmodium vivax remains an important cause of malaria in South America and Asia, and analyses of the antibody immune response are being used to identify biomarker of parasite exposure. The IgG antibody naturally acquired predominantly occurs against targets on blood-stage parasites, including C-terminal of the merozoite surface protein 1 (MSP1-19). Epidemiological and immunological evidence has been showed that antibodies to malaria parasite antigens are lost in the absence of ongoing exposure. Read More

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http://dx.doi.org/10.1016/j.actatropica.2020.105537DOI Listing

Arbovirus expansion: new species of culicids infected by the Chikungunya virus in an urban park of Brazil.

Acta Trop 2020 May 23:105538. Epub 2020 May 23.

Laboratory of Entomology Research, Department of Microbiology and Parasitology, Universidade Federal do Rio Grande do Norte, 59.078-970, Natal, Rio Grande do Norte, Brazil.

The Dengue, Zika and Chikungunya viruses have been spreading in tropical regions, causing epidemics with high morbidity rates and fatal cases. The aim of this study was to assess the diversity and abundance of culicid species and the presence of arboviruses in mosquitoes, at the epicenter of an epidemic outbreak that occurred in people living near an urban Atlantic Forest park. Mosquitoes were captured with a Shannon trap between 2 and 6 pm in seven months of 2019. Read More

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http://dx.doi.org/10.1016/j.actatropica.2020.105538DOI Listing

The effect of hydrophobic alkyl sidechains on size and solution behaviors of nanodiscs formed by alternating styrene maleamic copolymer.

Biochim Biophys Acta Biomembr 2020 May 23:183360. Epub 2020 May 23.

Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada. Electronic address:

The development of amphipathic polymers, including various formulations of styrene-maleic acid (SMA) copolymers, has allowed the purification of increasing sizes and complexities of biological membrane protein assemblies in native nanodiscs. However, the factors determining the sizes and shapes of the resulting bio-nano particles remain unclear. Here, we show how grafting on short alkyl amine sidechains onto the polar residues leads to a broad set of nanoparticle sizes with improved solution behavior. Read More

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http://dx.doi.org/10.1016/j.bbamem.2020.183360DOI Listing

Molecular organization in mixed SOPC and SDPC model membranes: Water permeability studies of polyunsaturated lipid bilayers.

Biochim Biophys Acta Biomembr 2020 May 23:183365. Epub 2020 May 23.

Department of Chemistry, Iona College, 715 North Avenue, New Rochelle, NY 10801, USA. Electronic address:

Polyunsaturated phospholipids in plasma membranes modulate order and dynamics of the lipid bilayer and influence integral membrane protein function. In this study, we investigate the effects of polyunsaturated fatty acid (PUFA) chains in phosphatidylcholine (PC) on osmotic water permeability and packing characteristics, using a droplet interface bilayer (DIB) as a model cell membrane. The lipid bilayer system is composed of mixtures of PC lipids with varying ratio of 1-stearoyl-2-oleoylphosphatidylcholine (SOPC, 18: 0-18:1 PC) to 1-stearoyl-2-docosahexaenoylphosphatidylcholine (SDPC, 18:0-22:6 PC). Read More

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http://dx.doi.org/10.1016/j.bbamem.2020.183365DOI Listing

Prevalence of retinitis pigmentosa in Singapore: the Singapore Epidemiology of Eye Diseases Study.

Acta Ophthalmol 2020 May 26. Epub 2020 May 26.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

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http://dx.doi.org/10.1111/aos.14483DOI Listing

Personalized medicine for the embryo and the fetus - Options in modern genetics influence preconception and prenatal choices.

Acta Obstet Gynecol Scand 2020 Jun;99(6):689-691

Center for Fetal Diagnostics, Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1111/aogs.13882DOI Listing

A sepsis risk calculator can decrease antibiotic exposure in neonatal early-onset sepsis screening.

Acta Paediatr 2020 May 26. Epub 2020 May 26.

Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1111/apa.15332DOI Listing

Agreement between three-dimensional planimetry and mitral navigation method in the assessment of mitral valve area in rheumatic severe mitral stenosis.

Acta Cardiol 2020 May 26:1-7. Epub 2020 May 26.

Department of Cardiology, Medipol University Hospital, Istanbul, Turkey.

Rheumatic heart disease predisposes to structural changes in the mitral valve including commissural fusion and calcification with subsequent narrowing of the mitral valve orifice resulting in rheumatic mitral stenosis (RMS). To define the best therapeutic strategy, an accurate measurement of mitral valve area (MVA) for RMS is of paramount importance. The propose of the present study was to assess the agreement between the mitral navigation method (MVN) and three-dimensional (3D) planimetry in the assessment of MVA in patients with RMS. Read More

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http://dx.doi.org/10.1080/00015385.2020.1764208DOI Listing

Predictors of in-hospital mortality in patients with infective endocarditis.

Acta Cardiol 2020 May 26:1-8. Epub 2020 May 26.

Division of Cardiology, Department of Medicine II, Kansai Medical University, Osaka, Japan.

Infective endocarditis is a serious septic disease, and the epidemiological profile has changed over the last decade. However, there is a paucity of data regarding the current outcome and predictor of in-hospital mortality in patients with infective endocarditis. Consecutive patients diagnosed as infective endocarditis based on the modified Duke criteria at Kansai Medical University hospital from January 2006 to June 2019 were prospectively included. Read More

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http://dx.doi.org/10.1080/00015385.2020.1767368DOI Listing

Q fever endocarditis.

Acta Cardiol 2020 May 26:1-2. Epub 2020 May 26.

Department of Cardiovascular Disease, CHU UCL Namur, Université Catholique de Louvain, Yvoir, Belgium.

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http://dx.doi.org/10.1080/00015385.2020.1762028DOI Listing

Impact of plaque burden and composition on coronary slow flow in ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: intravascular ultrasound and virtual histology analysis.

Acta Cardiol 2020 May 26:1-11. Epub 2020 May 26.

Department of Cardiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

Coronary slow flow (SF) is an important complication of percutaneous coronary intervention (PCI) associated with poor prognosis. The aim was to assess grey-scale intravascular ultrasound (IVUS) and virtual histology (VH-IVUS) characteristics of culprit lesion in ST-elevation myocardial infarction (STEMI). A total of 295 consecutive patients with STEMI underwent coronary angiogram and IVUS. Read More

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http://dx.doi.org/10.1080/00015385.2020.1767842DOI Listing

18F-FDG micro-PET/CT for intra-operative margin assessment during breast-conserving surgery.

Acta Chir Belg 2020 May 26:1-22. Epub 2020 May 26.

Department of Gynecology, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, Belgium.

Positive surgical margins for invasive breast cancer (BC) treated with breast-conserving surgery (BCS) are defined as ink on tumor. The rate of positive margins are approximately 20%, since a time- and cost-effective method for margin assessment is lacking. In this study, we investigated margin status by intra-operative imaging using high-resolution F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) and X-ray computed tomography (CT). Read More

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A new standard radiographic reference for proximal fibular height in children.

Acta Orthop 2020 May 26:1-6. Epub 2020 May 26.

Children's Orthopedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster.

Background and purpose - To date there is a lack of studies defining the anatomical position of the proximal fibula. This is especially relevant when planning surgical interventions affecting the knee joint such as permanent or temporary epiphysiodesis to correct leg length discrepancies or angular deformities in growing patients. The goal of this study is to establish a standardized measurement technique and radiological reference values for the position of the proximal fibula in children. Read More

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http://dx.doi.org/10.1080/17453674.2020.1769378DOI Listing

Implant migration and bone mineral density measured simultaneously by low-dose CT scans: a 2-year study on 17 acetabular revisions with impaction bone grafting.

Acta Orthop 2020 May 26:1-5. Epub 2020 May 26.

Department of Orthopedics Gävle Hospital, Center for Research & Development, Uppsala University/County Council of Gävleborg, Sweden.

Background and purpose - Early postoperative implant migration predicts failure of joint replacements. Bone mineral density reflects bone quality and bone-graft incorporation. Implant migration and bone densitometry analysis usually require special equipment. Read More

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http://dx.doi.org/10.1080/17453674.2020.1769295DOI Listing

Effective radiation dose in radiostereometric analysis of the hip.

Acta Orthop 2020 May 26:1-9. Epub 2020 May 26.

Department of Orthopaedic Surgery, Reinier de Graaf Groep, Delft, The Netherlands.

Background and purpose - Radiostereometric analysis (RSA) is the gold standard to study micromotion of joint replacements. RSA requires the acquisition of additional radiographs increasing the radiation dose of patients included in RSA studies. It is important to keep this dose as low as possible. Read More

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http://dx.doi.org/10.1080/17453674.2020.1767443DOI Listing

Aggressive fibromatosis of the upper arm: an unusual cause of radial nerve paresis.

Acta Neurol Belg 2020 May 25. Epub 2020 May 25.

Department of Radiology, AZ Sint-Maarten Mechelen, Liersesteenweg 435, 2800, Mechelen, Belgium.

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http://dx.doi.org/10.1007/s13760-020-01386-3DOI Listing

Author's response to letter from Drs. Vetrano, Devigili, and Nazzi.

Acta Neurochir (Wien) 2020 May 25. Epub 2020 May 25.

Friendly Foot Care, PC, 50 W. 94th Place, Crown Point, IN, 46307, USA.

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http://dx.doi.org/10.1007/s00701-020-04411-9DOI Listing
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