660,030 results match your criteria Across Languages And Cultures[Journal]


Abrupt changes in Great Britain vegetation carbon projected under climate change.

Glob Chang Biol 2020 May 28. Epub 2020 May 28.

Global Systems Institute, College of Life and Environmental Sciences, University of Exeter, Exeter, UK.

Past abrupt 'regime shifts' have been observed in a range of ecosystems due to various forcing factors. Large-scale abrupt shifts are projected for some terrestrial ecosystems under climate change, particularly in tropical and high-latitude regions. However, there is very little high-resolution modelling of smaller-scale future projected abrupt shifts in ecosystems, and relatively less focus on the potential for abrupt shifts in temperate terrestrial ecosystems. Read More

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http://dx.doi.org/10.1111/gcb.15144DOI Listing

The EACVI survey on cardiac imaging in cardio-oncology.

Eur Heart J Cardiovasc Imaging 2020 May 28. Epub 2020 May 28.

Department of Cardiology, Oslo University Hospital, Postboks 4950 Nydalen, 0424 Oslo, Norway.

Early and late cardiovascular (CV) toxicities related to many cancer treatments may complicate the clinical course of patients, offsetting therapeutic benefits, and altering prognosis. The early detection, monitoring, and treatment of cardiotoxicity have therefore become essential parts of cancer patient care. CV imaging is a cornerstone of every cardio-oncology unit, but its use may vary across Europe because of the non-uniform availability of advanced imaging techniques and differences in the organization and logistics of cardio-oncology services. Read More

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http://dx.doi.org/10.1093/ehjci/jeaa111DOI Listing

Effect of fetal growth restriction on urinary podocalyxin levels at birth in preterm neonates.

Pediatr Res 2020 May 28. Epub 2020 May 28.

Department of Neonatology, Government Medical College Hospital, Chandigarh, India.

Background: Small-for-gestational-age (SGA) neonates are at a higher risk of adult-onset metabolic disorders because of fetal programming in the presence of growth restriction. Nephrogenesis may also be affected in fetal growth restriction. This study hypothesized that urinary podocalyxin levels, a marker of nephrogenesis, would be lower among preterm SGA neonates as compared to appropriate-for-gestational-age (AGA) controls. Read More

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http://dx.doi.org/10.1038/s41390-020-0987-2DOI Listing

Ambient particle radioactivity and gestational diabetes: A cohort study of more than 1 million pregnant women in Massachusetts, USA.

Sci Total Environ 2020 May 11;733:139340. Epub 2020 May 11.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Background: Exposure to ionizing radiation increases the risk of chronic metabolic disorders such as insulin resistance and type 2 diabetes. Internal ionizing radiation from inhaled radioactive aerosol may contribute to the associations between fine particulate matter (PM) and gestational diabetes mellitus (GDM).

Methods: We used the Massachusetts Registry of Vital Records to study 1,061,937 pregnant women from 2001 to 2015 with a singleton pregnancy without pre-existing diabetes. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139340DOI Listing

Inclusion of seasonal variation in river system microbial communities and phototroph activity increases environmental relevance of laboratory chemical persistence tests.

Sci Total Environ 2020 Apr 30;733:139070. Epub 2020 Apr 30.

School of Life Sciences, Gibbet Hill Campus, University of Warwick, Coventry CV4 7AL, UK.

Regulatory tests assess crop protection product environmental fate and toxicity before approval for commercial use. Although globally applied laboratory tests can assess biodegradation, they lack environmental complexity. Microbial communities are subject to temporal and spatial variation, but there is little consideration of these microbial dynamics in the laboratory. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139070DOI Listing

Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study.

EBioMedicine 2020 May 25;56:102785. Epub 2020 May 25.

Department of Neurosurgery, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary; Neurotrauma Research Group, Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, H-7624 Pécs, Hungary.

Background: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to correlate serum biomarkers with clinical severity, care path and imaging abnormalities in TBI, and explore their incremental value over clinical characteristics in predicting computed tomographic (CT) abnormalities.

Methods: We analyzed six serum biomarkers (S100B, NSE, GFAP, UCH-L1, NFL and t-tau) obtained <24 h post-injury from 2867 patients with any severity of TBI in the Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI) Core Study, a prospective, multicenter, cohort study. Read More

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http://dx.doi.org/10.1016/j.ebiom.2020.102785DOI Listing

Arthropod biodiversity patterns point to the Mesovoid Shallow Substratum (MSS) as a climate refugium.

Zoology (Jena) 2020 Apr 25;141:125771. Epub 2020 Apr 25.

Research Team on Soil Biology and Subterranean Ecosystems, Department of Life Science, Faculty of Science, University Campus, University of Alcalá, A.P. 20, E-28871, Alcalá de Henares, Madrid, Spain.

The determinants of biodiversity patterns in the subterranean habitat called Mesovoid Shallow Substratum (MSS) are not well-understood. In this study, thirty-three scree slopes at high altitudes were selected across the Sierra de Guadarrama National Park in central Spain to investigate the effect of ten environmental variables on the abundance and species diversity of the spider and springtail assemblages from the colluvial MSS. In each locality, a multiperforated PVC tube with a pitfall trap inside was buried up to 1 m deep, and generalized linear models and Mantel tests were used to analyze the effect of mainly climate- and habitat-related variables on the diversity patterns of both taxa. Read More

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http://dx.doi.org/10.1016/j.zool.2020.125771DOI Listing

Effects of transcranial direct current stimulation using miniaturized devices vs sertraline for depression in Korea: A 6 week, multicenter, randomized, double blind, active-controlled study.

J Psychiatr Res 2020 May 8;127:42-47. Epub 2020 May 8.

Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Gyeonggi, South Korea; Center for Digital Health, Yongin Severance Hospital, Yonsei University Health System, Yongin, Gyeonggi, South Korea. Electronic address:

We compared the efficacy and safety of transcranial direct current stimulation (tDCS) vs. Sertraline in the treatment of Major Depressive Disorder (MDD) in South Korean participants. This was a multi-center, double blind, active controlled study with non-inferiority testing. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2020.04.012DOI Listing

Alcohol advertisement characteristics that increase the likelihood of code breaches.

Int J Drug Policy 2020 May 25;81:102776. Epub 2020 May 25.

Cancer Council Western Australia, 420 Bagot Road, Subiaco, WA, 6008. Electronic address:

Background: Exposure to alcohol advertising is associated with adverse outcomes among youth. Alcohol advertising codes attempt to ensure that alcohol promotion meets community standards, especially in relation to minimising the exposure of children and young people. The aim of the present study was to assess the characteristics of Australian alcohol advertisements that breach the Alcohol Advertising Review Board's (AARB) Code, with a particular focus on provisions relating to youth exposure. Read More

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http://dx.doi.org/10.1016/j.drugpo.2020.102776DOI Listing

Detailed evaluation of Mobius3D dose calculation accuracy for volumetric-modulated arc therapy.

Phys Med 2020 May 25;74:125-132. Epub 2020 May 25.

Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

Purpose: To perform a detailed evaluation of dose calculation accuracy and clinical feasibility of Mobius3D. Of particular importance, multileaf collimator (MLC) modeling accuracy in the Mobius3D dose calculation algorithm was investigated.

Methods: Mobius3D was fully commissioned by following the vendor-suggested procedures, including dosimetric leaf gap (DLG) optimization. Read More

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http://dx.doi.org/10.1016/j.ejmp.2020.05.015DOI Listing

Item Response Theory analyses of DSM-5 substance use disorder criteria in French outpatient addiction clinic participants. How much is craving special?

Drug Alcohol Depend 2020 May 12;212:108036. Epub 2020 May 12.

University of Bordeaux, Phenomenology and Determinants of Appetitive Behaviors (Addiction Team), Sleep, Addiction and Neuropsychiatry Laboratory (SANPSY), USR CNRS 3413, 146 Bis Rue Léo Saignat, 33076, Bordeaux, France; Pôle Addictologie, CH Ch. Perrens and CHU de Bordeaux, 121 Rue De La Béchade, 33076, Bordeaux, France; Center for Studies of Addiction, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market St, Suite 4000, Philadelphia, PA 19104, USA. Electronic address:

Background: To evaluate the dimensionality and psychometric validity of the 11 DSM-5 criteria for 5 substance use disorders, with a focus on craving, and taking into account age, gender and psychiatric comorbidities in a French sample of subjects seeking addiction treatment.

Methods: This cross-sectional study, included participants with DSM-5 substance use disorders that sought treatment for at least one addiction from outpatient clinics. Diagnostic criteria were evaluated with the Mini international Neuropsychiatric Interview. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2020.108036DOI Listing

Evaluating peripheral versus central contributions to spectral context effects in speech perception.

Hear Res 2020 May 15;392:107983. Epub 2020 May 15.

Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY, 40292, USA. Electronic address:

Perception of a sound is influenced by spectral properties of surrounding sounds. When frequencies are absent in a preceding acoustic context before being introduced in a subsequent target sound, detection of those frequencies is facilitated via an auditory enhancement effect (EE). When spectral composition differs across a preceding context and subsequent target sound, those differences are perceptually magnified and perception shifts via a spectral contrast effect (SCE). Read More

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http://dx.doi.org/10.1016/j.heares.2020.107983DOI Listing

ROTEM diagnostic capacity for measuring fibrinolysis in neonatal sepsis.

Thromb Res 2020 May 20;192:103-108. Epub 2020 May 20.

Laboratory of Haematology and Blood Bank Unit, "Attiko" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

Background: Hypofibrinolysis has been demonstrated in several studies in adult sepsis. Although fibrinolysis is an important and integral part of the hemostatic system, few data are available regarding its role in neonatal sepsis. Our purpose was to define fibrinolytic profiles across neonatal sepsis spectrum using rotational thromboelastometry (ROTEM). Read More

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http://dx.doi.org/10.1016/j.thromres.2020.05.028DOI Listing

Ranking of ecosystem services on the basis of willingness to pay: Monetary assessment of a subset of ecosystem services in the Heihe River basin.

Sci Total Environ 2020 May 14;734:139447. Epub 2020 May 14.

College of Economics and Management, Northwest A&F University, Yangling 712100, Shaanxi, China. Electronic address:

The identification of public preferences and the welfares of river system evaluation are consequential for effective renovation of river system as well as viable river management. For this reason, the focus of current study was emphasized on respondent's willingness to pay through implementation of Random Parameter Logit model using data collected through choice experiment technique, in which the preferences of sampled respondent's in urban, rural and pooled data was evaluated for different abiotic and biotic ecosystem services across the entire Heihe River Basin. The estimated results revealed that average urban households are willing to pay more for the restoration of ecosystem services compared to rural residents. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139447DOI Listing

Good times, bad times: Resource pulses influence mammal diversity in meridional Brazilian highlands.

Sci Total Environ 2020 May 15;734:139473. Epub 2020 May 15.

Universidade de São Paulo (USP), Escola Superior de Agricultura "Luiz de Queiroz" (ESALQ), Departamento de Ciências Florestais, Laboratório de Ecologia, Manejo e Conservação de Fauna Silvestre (LEMaC), Piracicaba, SP 13418-900, Brazil.

Understanding spatiotemporal patterns of species distributions and their determinants is paramount in ecology. Here, we explore the relationship between the diversity of surviving mammals and two of the main alimentary resources (araucaria seeds and feijoa fruits) across the Araucaria Forest (FOM) in South America. First, we investigated the influence of landscape and environment on the species distribution and pulse of forest productivity. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139473DOI Listing

Cumulative impact assessment for ecosystem-based marine spatial planning.

Sci Total Environ 2020 May 11;734:139024. Epub 2020 May 11.

NIVA Denmark Water Research, Copenhagen, Denmark.

Claims for ocean space are growing while marine ecosystems suffer from centuries of insufficient care. Human pressures from runoff, atmospheric emissions, marine pollution, fishing, shipping, military operations and other activities wear on habitats and populations. Ecosystem-based marine spatial planning (MSP) has emerged worldwide as a strategic instrument for handling conflicting spatial claims among competing sectors and the environment. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139024DOI Listing

Synchrony of globally invasive Aedes spp. immature mosquitoes along an urban altitudinal gradient in their native range.

Sci Total Environ 2020 May 13;734:139365. Epub 2020 May 13.

School of Tropical Medicine and Global Health, Nagasaki University, Sakamoto 1-12-4, Nagasaki 852-8523, Japan.

Mosquito-borne infections often have concerted peaks, or are synchronous, across landscapes. This phenomenon might be driven by vector responses to similar environmental conditions that synchronize their abundance. While adult mosquito populations can be synchronous over spatial scales ranging from a few meters to a few kilometers, little to nothing is known about immature mosquito synchrony, including its relationship with mosquito colonization and persistence in larval habitats. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139365DOI Listing

Control it and it is yours: Children's reasoning about the ownership of living things.

Cognition 2020 May 25;202:104319. Epub 2020 May 25.

Department of Psychology, University of Toronto, Canada. Electronic address:

One of the hallmarks of ownership is the right to control one's property. Living beings thus pose an interesting puzzle for ownership, since they have some capacity to decide what happens to themselves-they can direct their own motion, pursue their own goals, and make their own decisions. Recent work has shown that adults consider this autonomy to be the key factor in determining whether a human (or human-like) being can be owned. Read More

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http://dx.doi.org/10.1016/j.cognition.2020.104319DOI Listing

Risk Scores Did Not Reliably Predict Individual Risk Of Mortality For Patients With Decompensated Heart Failure.

J Clin Epidemiol 2020 May 25. Epub 2020 May 25.

Istituti Clinici Scientifici Maugeri, I.R.C.C.S, Pavia. Italy.

Objective: We investigated the performance of four prognostic tools in predicting 180-day mortality for patients admitted for decompensated heart failure (ADHF) by calculating sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) over a range of risk thresholds, in addition to discrimination and calibration.

Study Design And Setting: We studied 1,458 patients. Risk assessment was performed using the ADHERE model and the GWTG, ADHF/NT-proBNP, and ASCEND risk scores. Read More

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http://dx.doi.org/10.1016/j.jclinepi.2020.05.020DOI Listing

Improved tolerability of neratinib in patients with HER2-positive early-stage breast cancer: diarrheal toxicity in the CONTROL trial.

Ann Oncol 2020 May 25. Epub 2020 May 25.

Breast Cancer Research Centre-WA & Curtin University, Perth, WA, Australia.

Background: Neratinib is an irreversible pan-HER tyrosine kinase inhibitor approved for extended adjuvant treatment in early-stage HER2-positive breast cancer based on the phase III ExteNET study. In that trial, in which no anti-diarrheal prophylaxis was mandated, grade 3 diarrhea was observed in 40% of patients and 17% discontinued due to diarrhea. The international, open-label, sequential-cohort, phase II CONTROL study is investigating several strategies to improve tolerability. Read More

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http://dx.doi.org/10.1016/j.annonc.2020.05.012DOI Listing

Molecular mechanisms of Guadecitabine induced FGFR4 down regulation in alveolar rhabdomyosarcomas.

Neoplasia 2020 May 25;22(7):274-282. Epub 2020 May 25.

Division of Hematology-Oncology, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

Fibroblast growth factor receptor 4 (FGFR4) aberrant expression and activity have been linked to the pathogenesis of a variety of cancers including rhabdomyosarcomas (RMS). We found that treatment of alveolar rhabdomyosarcoma (aRMS) cells with Guadecitabine (SGI-110), a next-generation DNA methyltransferase inhibitor (DNMTi), resulted in a significant reduction of FGFR4 protein levels, 5 days post treatment. Chromatin immunoprecipitation-sequencing (ChIP-seq) in aRMS cells revealed attenuation of the H3K4 mono-methylation across the FGFR4 super enhancer without changes in tri-methylation of either H3K4 or H3K27. Read More

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http://dx.doi.org/10.1016/j.neo.2020.05.001DOI Listing

Poorly suited heart valve prostheses heighten the plight of patients with rheumatic heart disease.

Int J Cardiol 2020 May 25. Epub 2020 May 25.

Christiaan Barnard Department of Cardiothoracic Surgery, University of Cape Town, South Africa. Electronic address:

Rheumatic heart disease (RHD) still affects more patients globally than degenerative valve disease. The vast majority of these patients live in low- to middle-income countries. Once symptomatic, they will need heart valve surgery. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.05.073DOI Listing

An analytical workflow for seed-based correlation and independent component analysis in interventional resting-state fMRI studies.

Neurosci Res 2020 May 25. Epub 2020 May 25.

Centre for Microscopy, Characterisation and Analysis, Research Infrastructure Centres, The University of Western Australia, Perth, WA, Australia; School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia. Electronic address:

Resting-state functional MRI (rs-fMRI) is a task-free method of detecting spatially distinct brain regions with correlated activity, which form organised networks known as resting-state networks (RSNs). The two most widely used methods for analysing RSN connectivity are seed-based correlation analysis (SCA) and independent component analysis (ICA) but there is no established workflow of the optimal combination of analytical steps and how to execute them. Rodent rs-fMRI data from our previous longitudinal brain stimulation studies were used to investigate these two methods using FSL. Read More

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http://dx.doi.org/10.1016/j.neures.2020.05.006DOI Listing

Acute Kidney Injury Events in Patients With Type 2 Diabetes Using SGLT2 Inhibitors Versus Other Glucose-Lowering Drugs: A Retrospective Cohort Study.

Am J Kidney Dis 2020 May 25. Epub 2020 May 25.

University of Manitoba, Rady Faculty of Health Sciences, Max Rady College of Medicine, Department of Internal Medicine; Seven Oaks Hospital, Chronic Disease Innovation Centre.

Rationale & Objective: Sodium glucose cotransporter 2 (SGLT2) inhibitors slow the progression of chronic kidney disease and prevent heart failure events. However, SGLT2 inhibitors may increase the risk of acute kidney injury (AKI). Our objective was to assess whether SGLT2 inhibitor use, compared to all other glucose lowering drugs (oGLD), is associated with increased rates of AKI. Read More

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http://dx.doi.org/10.1053/j.ajkd.2020.03.019DOI Listing

Generalization and Discrimination of Molecularly Similar Odorants in Detection Canines and the Influence of Training.

Behav Processes 2020 May 25:104148. Epub 2020 May 25.

Florida International University, International Forensic Research Institute, Chemistry Department, 11200 SW 8(th)St., Miami, FL, 33199, USA.

Operationally-deployed canine detectors are often trained on one or a limited number of materials representing a single target odor, and training frequently occurs using materials of a high purity grade in controlled scenarios with minimal other background odors. Conversely, in the field, canine detectors are expected to generalize and identify variations of the target odor, while discriminating from similar extraneous or background odors. This exemplifies the balance between generalization and discrimination required for effective canine detectors. Read More

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http://dx.doi.org/10.1016/j.beproc.2020.104148DOI Listing

The effects of novelty on food consumption in male and female rats.

Physiol Behav 2020 May 25:112970. Epub 2020 May 25.

Department of Psychology & Neuroscience, Boston College, Chestnut Hill, MA 02467, United States. Electronic address:

Novelty powerfully impacts feeding behavior and can override homeostatic and hedonic drives, because consumption of a new food could lead to illness or even death. New foods and new feeding environments can decrease or inhibit feeding, but how the two interact and whether there are sex differences has not been determined. The current study examined consumption of a palatable (high sucrose) novel food compared to a familiar food in adult male and female rats that were fed in a familiar or a novel environment. Read More

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http://dx.doi.org/10.1016/j.physbeh.2020.112970DOI Listing

Countermeasures-based Improvements in Stress, Immune System Dysregulation and Latent Herpesvirus Reactivation onboard the International Space Station - Relevance for Deep Space Missions and Terrestrial Medicine.

Neurosci Biobehav Rev 2020 May 25. Epub 2020 May 25.

JES Tech, Houston, Texas, United States.

The International Space Station (ISS) has continued to evolve from an operational perspective and multiple studies have monitored both stress and the immune system of ISS astronauts. Alterations were ascribed to a potentially synergistic array of factors, including microgravity, radiation, psychological stress, and circadian misalignment. Comparing similar data across 12 years of ISS construction and operations, we report that immunity, stress, and the reactivation of latent herpesviruses have all improved in ISS astronauts. Read More

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http://dx.doi.org/10.1016/j.neubiorev.2020.05.007DOI Listing

Relationship Between Behavioral and Stimulus Frequency Otoacoustic Emissions Delay-Based Tuning Estimates.

J Speech Lang Hear Res 2020 May 28:1-11. Epub 2020 May 28.

Roxelyn and Richard Pepper Department of Communication Sciences & Disorders, Northwestern University, Evanston, IL.

Purpose The phase delay of stimulus frequency otoacoustic emissions (SFOAEs) has been proposed as a noninvasive, objective, and fast source for estimating cochlear mechanical tuning. However, the implementation of SFOAEs clinically has been thwarted by the gaps in understanding of the stability of SFOAE delay-based tuning estimates and their relationship to behavioral measures of tuning. Therefore, the goals of this study were (a) to investigate the relationship between delay-based tuning estimates from SFOAEs and simultaneously masked psychophysical tuning curves (PTCs) and (b) to assess the across- and within-session repeatability of tuning estimates from behavioral and OAE measures. Read More

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http://dx.doi.org/10.1044/2020_JSLHR-19-00386DOI Listing

Interdental Cleaning and Oral Health Status in an Adult Cohort, 2015 to 2018.

J Dent Res 2020 May 28:22034520926139. Epub 2020 May 28.

Division of Oral Epidemiology and Dental Public Health, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.

Interdental cleaning is routinely recommended, despite limited evidence supporting efficacy to prevent advanced oral disease endpoints, such as caries and periodontal disease. We aimed to examine associations between interdental cleaning and oral health in a large, generalizable prospective cohort of adults in the United States. Data were drawn from wave 3 (2015 to 2016, = 26,086 included in analysis) and wave 4 (2016 to 2018, = 22,585) of the adult component (age ≥18 y) of the nationally representative Population Assessment of Tobacco and Health Study. Read More

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http://dx.doi.org/10.1177/0022034520926139DOI Listing

The changing nature of organic carbon over the United States.

Environ Sci Technol 2020 May 28. Epub 2020 May 28.

Total organic carbon (TOC) mass concentrations are decreasing across the contiguous US (CONUS). We investigate decadal trends in organic carbon (OC) thermal fractions (OC1 (volatilizes at 140 °C), OC2 (280 °C), OC3 (480 °C), OC4 (580 °C)), and pyrolyzed carbon (PC), reported at 121 locations in the Interagency Monitoring of PROtected Visual Environments (IMPROVE) network from 2005-2015 for 23 regions across the CONUS. Reductions in PC and OC2 drive decreases in TOC (TOC=OC1+OC2+OC3+OC4+PC) mass concentrations. Read More

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http://dx.doi.org/10.1021/acs.est.0c02225DOI Listing

Understanding Virtual Urology Clinics: A Systematic Review.

BJU Int 2020 May 28. Epub 2020 May 28.

Division of Surgery, Imperial Prostate, Department of Surgery and Cancer, Imperial College London, Charing Cross Campus, W6 8RF, UK.

Objective: To perform a systematic review to identify the clinical, fiscal and environmental evidence on the use of urological telehealth and/or virtual clinic strategies. Our secondary aim was to highlight research gaps in this rapidly evolving field.

Methods: Our PROSPERO registered (CRD42019151946) systematic search of Embase, Medline and Cochrane Review Database was performed for original research articles pertaining to adult urology telehealth or virtual clinic strategies. Read More

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http://dx.doi.org/10.1111/bju.15125DOI Listing

Clinical Study of the Influence of Ambient Lighting Conditions on the Mesh Quality of an Intraoral Scanner.

J Prosthodont 2020 May 28. Epub 2020 May 28.

Assistant Faculty Mechanical Engineering, Texas A&M University, College Station, TX.

Purpose: To compute the effect of ambient light illuminance settings on the mesh quality of the digital scans accomplished in a subject.

Material And Methods: A subject was recruited. The maxillary dentition did not present any dental restoration. Read More

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http://dx.doi.org/10.1111/jopr.13205DOI Listing

The gut microbiota of invasive bullfrog tadpoles responds more rapidly to temperature than a non-invasive congener.

Mol Ecol 2020 May 28. Epub 2020 May 28.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.

Environmental temperature can alter the composition, diversity, and function of ectothermic vertebrate gut microbial communities, which may result in negative consequences for host physiology, or conversely, increase phenotypic plasticity and persistence in harsh conditions. The magnitude of either of these effects will depend on the length of time animals are exposed to extreme temperatures, and how quickly the composition and function of the gut microbiota can respond to temperature change. However, the temporal effects of temperature on gut microbiota are currently unknown. Read More

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http://dx.doi.org/10.1111/mec.15487DOI Listing

Allometric constraints and competition enable the simulation of size structure and carbon fluxes in a dynamic vegetation model of tropical forests (LM3PPA-TV).

Glob Chang Biol 2020 May 28. Epub 2020 May 28.

Smithsonian Tropical Research Institute, 0843-03092, Balboa, Ancón, Panamá.

Tropical forests are a key determinant of the functioning of the Earth system, but remain a major source of uncertainty in carbon cycle models and climate change projections. In this study, we present an updated land model (LM3PPA-TV) to improve the representation of tropical forest structure and dynamics in Earth system models (ESMs). The development and parameterization of LM3PPA-TV drew on extensive datasets on tropical tree traits and long-term field censuses from Barro Colorado Island (BCI), Panama. Read More

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http://dx.doi.org/10.1111/gcb.15188DOI Listing

BEVA primary care clinical guidelines: Wound Management in the Horse.

Equine Vet J 2020 May 28. Epub 2020 May 28.

Waikato Equine Veterinary Centre, Cambridge, New Zealand.

Background: There are currently no evidence summaries on wounds in the horse.

Objectives: To develop evidence-based guidelines on wound management in the horse. Study design Evidence review using the GRADE framework METHODS: Research questions were proposed by a panel of veterinarians, and developed into PICO format. Read More

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http://dx.doi.org/10.1111/evj.13289DOI Listing

Foliar functional traits from imaging spectroscopy across biomes in eastern North America.

New Phytol 2020 May 28. Epub 2020 May 28.

Department of Forest and Wildlife Ecology, University of Wisconsin-Madison, 1630 Linden Drive, Madison, WI, 53706, USA.

Foliar functional traits are widely used to characterize leaf and canopy properties that drive ecosystem processes and to infer physiological processes in Earth system models. Imaging spectroscopy provides great potential to map foliar traits to characterize continuous functional variation and diversity, but few studies have demonstrated consistent methods for mapping multiple traits across biomes. With airborne imaging spectroscopy data and field data from 19 sites, we developed trait models using partial least squares regression, and mapped 26 foliar traits in 7 NEON (National Ecological Observatory Network) ecoregions (domains) including temperate and subtropical forests and grasslands of eastern North America. Read More

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http://dx.doi.org/10.1111/nph.16711DOI Listing

Macroevolutionary patterns in seed component mass and different evolutionary trajectories across seed desiccation responses.

New Phytol 2020 May 28. Epub 2020 May 28.

Millennium Seed Bank, Royal Botanic Gardens Kew, Wakehurst, West Sussex, RH17 6TN, UK.

Seed coat and seed reserve show substantial mass variation, play different roles in plant life strategies and are shaped by different selective forces. However, remarkably little is known about the macroevolution of the relative allocation in seed components and its influence on important ecophysiological processes. Using phylogenetic comparative methods and evolutionary modelling approaches, we modelled mass changes in seed components along individual lineages for 940 species and compared the patterns across seed desiccation responses. Read More

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http://dx.doi.org/10.1111/nph.16706DOI Listing

Nurse Graduates' Perceived Educational Needs After the Death of a Patient: A Descriptive Qualitative Research Study.

J Contin Educ Nurs 2020 Jun;51(6):267-273

Background: Nurse graduates (NGs) are ill prepared when faced with patient death and dying, despite receiving educational preparation on end-of-life (EOL) care in their prelicensure nursing programs.

Method: This qualitative descriptive study included a convenience sample of NGs (n = 20) who experienced a first adult patient death during their first 18 months of practice at a large teaching hospital with an extensive NG transition program, including preceptor-guided orientations, nurse internship programs, and nurse residency programs.

Results: Six major themes described the NG experience: Navigating the Process, Not Prepared, Support, Missed Opportunities, Preparing NGs for Death and Dying, and Guiding NGs Through Practice. Read More

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http://dx.doi.org/10.3928/00220124-20200514-06DOI Listing

Cortical Volume Differences in Subjects at Risk for Psychosis Are Driven by Surface Area.

Schizophr Bull 2020 May 28. Epub 2020 May 28.

The Zurich Program for Sustainable Development of Mental Health Services (ZInEP), University Hospital of Psychiatry Zurich, Zurich, Switzerland.

In subjects at risk for psychosis, the studies on gray matter volume (GMV) predominantly reported volume loss compared with healthy controls (CON). However, other important morphological measurements such as cortical surface area (CSA) and cortical thickness (CT) were not systematically compared. So far, samples mostly comprised subjects at genetic risk or at clinical risk fulfilling an ultra-high risk (UHR) criterion. Read More

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http://dx.doi.org/10.1093/schbul/sbaa066DOI Listing

Radiation risks and uncertainties: a scoping review to support communication and informed decision-making.

J Radiol Prot 2020 May 28;40(2):612-632. Epub 2020 May 28.

Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium. University of Antwerp, Antwerp, Belgium.

Although radiation protection is challenged by many uncertainties, there is no systematic study investigating the definitions and types of these uncertainties. To address this gap, in this paper we offer a scoping review to comprehensively analyse, for the first time, peer-reviewed scientific articles (n = 33) related to uncertainties in the following radiation exposure situations: nuclear emergencies, decommissioning of nuclear/radiological installations and long-term radiological exposure situations (e.g. Read More

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http://dx.doi.org/10.1088/1361-6498/ab885fDOI Listing

Positioning and utilization of information and communication technology (ICT) in community pharmacies: a cross sectional study from Selangor, Malaysia.

JMIR Med Inform 2020 May 13. Epub 2020 May 13.

Unaizah College of Pharmacy, Qassim University, Unaizah, SA.

Background: Information and communication technology (ICT) is an essential element of modern "smart" cities. These smart cities have integrated housing, marketplace, public amenities, services, business and transportation linked via the ICT. ICT is also used widely in urban healthcare delivery. Read More

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http://dx.doi.org/10.2196/17982DOI Listing

Patient Medication Adherence Among Pharmacies Participating in a North Carolina Enhanced Services Network.

J Manag Care Spec Pharm 2020 Jun;26(6):718-722

University of Minnesota College of Pharmacy, Minneapolis.

Background: Improving medication adherence can reduce health care spending, and studies have demonstrated community pharmacists can positively affect adherence through the provision of enhanced services. The North Carolina (NC) Community Pharmacy Enhanced Services Network (CPESN) was formed in early 2014 with the goal of enhancing the care provided through its network pharmacies.

Objective: To evaluate differences in medication adherence performance scores between pharmacies that participated in the NC-CPESN and control pharmacies in NC that did not. Read More

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http://dx.doi.org/10.18553/jmcp.2020.26.6.718DOI Listing

The journey from nurse to advanced nurse practitioner: applying concepts of role transitioning.

Br J Nurs 2020 May;29(10):561-565

Head of Research Ethnics/Professor of Health Psychology, Centre for Behavioural Science and Applied Psychology, Sheffield Hallam University, Sheffield.

The advanced nurse practitioner (ANP) role was established in Ireland in 2001 and represents an important nursing role development within Irish healthcare. Currently there are 336 ANPs registered with the Nursing and Midwifery Board of Ireland, working across 40 specialties. This number is increasing exponentially in response to emerging and anticipated future service needs and population demand projecting to a critical mass of 750 by 2021. Read More

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http://dx.doi.org/10.12968/bjon.2020.29.10.561DOI Listing

Formulation of pluronic F127/TPGS mixed micelles to improve the oral absorption of Glycyrrhizic acid.

Drug Dev Ind Pharm 2020 May 28:1-21. Epub 2020 May 28.

Pharmacy college, Chengdu University of Traditional Chinese Medicine, Chengdu, 611139, China.

Glycyrrhizic acid (GL), a pentacyclic triterpenoid glycoside, has been used as a hepatoprotective agent for the treatment of acute and chronic hepatitis. However, its poor solubility and permeability across the gastrointestinal mucosa limit its clinical efficacy. This study aimed to develop mixed micelles based on pluronic F127 and D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) to improve the oral bioavailability of GL. Read More

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http://dx.doi.org/10.1080/03639045.2020.1775634DOI Listing

A Systematic Review of the Physiological Effects of the Effortful Swallow Maneuver in Adults With Normal and Disordered Swallowing.

Am J Speech Lang Pathol 2020 May 28:1-19. Epub 2020 May 28.

Department of Communication Sciences and Disorders, Syracuse University, NY.

Purpose This systematic review summarizes the biomechanical and functional effects of the effortful swallow in adults with and without dysphagia, highlighting clinical implications and future research needs. Specifically, the effects of the effortful swallow on swallowing physiology, safety, and efficiency were identified, as well as the strengths and limitations of current research. Method Recommendations specified by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses were followed. Read More

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http://dx.doi.org/10.1044/2020_AJSLP-19-00132DOI Listing

Achieving Participation-Focused Intervention Through Shared Decision Making: Proposal of an Age- and Disorder-Generic Framework.

Am J Speech Lang Pathol 2020 May 28:1-26. Epub 2020 May 28.

Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson.

Introduction The World Health Organization's International Classification of Functioning, Disability and Health calls on speech-language pathologists (SLPs) to provide care that impacts all aspects of an individual's experience with a communication disorder, including their participation in valued life situations. However, SLPs often report feeling unprepared to implement and document interventions that target life participation. The purpose of this article is to propose a framework to guide participation-focused intervention practices. Read More

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http://dx.doi.org/10.1044/2020_AJSLP-19-00043DOI Listing

Convenient Route to Heterometallic Group 4-Zinc Precursors for Binary Oxide Nanomaterials.

Inorg Chem 2020 May 28. Epub 2020 May 28.

Łukasiewicz Research Network - PORT Polish Center For Technology Development, 147 Stablowicka, 54-066 Wrocław, Poland.

In this study, simple and efficient synthetic routes to a family of uncommon group 4-zinc heterometallic alkoxides were developed. Single-source molecular precursors with the structures [CpTiZn(μ,η-OR)(THF)Cl] (), [ZrZn(μ-O)(μ,η-OR)(μ-OH)(μ,η-OR)(μ,η-OR)Cl] (), and [HfZn(μ-O)(μ,η-OR)(μ-OH)(μ,η-OR)(μ,η-OR)Cl] () were prepared via reduction of CpTiCl with metallic zinc or protonolysis of the metal-cyclopentadienyl bond in CpM'Cl (M' = Zr or Hf) in the presence of 2-methoxyethanol (ROH) and Zn(OR). This synthetic route enables the creation of compounds with well-defined molecular structures and therefore provides precursors suitable for obtaining group 4-zinc oxides. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.0c00399DOI Listing

Specific learning disorders in sex chromosome aneuploidies: Neural circuits of literacy and mathematics.

Am J Med Genet C Semin Med Genet 2020 May 28. Epub 2020 May 28.

Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, California, USA.

Sex chromosome aneuploidies (SCA) are associated with an increased risk for specific learning disorders (SLD). Individuals with Klinefelter Syndrome (KS) show an increased incidence of developmental dyslexia and individuals with Turner Syndrome (TS) are often affected by developmental dyscalculia. Accordingly, KS frequently coincides with verbal deficits, and TS with visual-spatial impairments. Read More

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http://dx.doi.org/10.1002/ajmg.c.31801DOI Listing

Assessment of Brix refractometry to estimate immunoglobulin G concentration in beef cow colostrum.

J Vet Intern Med 2020 May 28. Epub 2020 May 28.

Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, Calgary, Alberta, Canada.

Background: Brix refractometry can be used to assess colostral immunoglobulin G (IgG) concentration, but studies identifying Brix percentages to detect high- and low-IgG colostrum are lacking for beef cows and interlaboratory agreement is unknown.

Objectives: Evaluate Brix refractometer performance and interlaboratory agreement for assessing beef cow colostrum IgG concentration, including determination of thresholds to identify colostrum containing IgG concentrations <100 g/L and ≥150 g/L.

Animals: Beef cows (n = 416) from 11 cow-calf operations in Alberta, Canada. Read More

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http://dx.doi.org/10.1111/jvim.15805DOI Listing

ZIF-induced d-band Modification in Bimetallic Nanocatalyst: Achieving >44% Efficiency in Ambient Nitrogen Reduction Reaction.

Angew Chem Int Ed Engl 2020 May 28. Epub 2020 May 28.

Nanyang Technological University, Division of Chemistry & Biological Chemistry, 21 Nanyang Link,, Nanyang Technological University,, 637371, Singapore, SINGAPORE.

Electrochemical nitrogen reduction reaction (NRR) offers a sustainable solution towards ammonia production but suffers poor reaction performance due to preferential catalyst-H formation and the consequential hydrogen evolution reaction (HER). Herein, we electronically modify PtAu electrocatalyst d-band structure using zeolitic-imidazole framework (ZIF) to achieve a faradaic efficiency (FE) of >44% with high ammonia yield rate of >161 µg.mg cat -1 . Read More

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http://dx.doi.org/10.1002/anie.202006071DOI Listing
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