2,581 results match your criteria Acrodermatitis Chronica Atrophicans
Postepy Dermatol Alergol 2018 Oct 19;35(5):490-494. Epub 2018 Jul 19.
Department of Infectious Diseases and Neuroinfections, Medical University of Białystok, Białystok, Poland.
Introduction: Acrodermatitis chronica atrophicans (ACA) is probably the most common late and chronic manifestation of the Lyme borreliosis seen in European patients.
Aim: To analyze epidemiological data, and to investigate the effects of treatment of patients with ACA.
Material And Methods: Nine patients were included in the study. Read More
Br J Dermatol 2018 Nov 8. Epub 2018 Nov 8.
Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Acrodermatitis continua of Hallopeau (ACH) is a rare acropustular subtype of psoriasis. The characteristic feature of ACH is chronic, painful and destructive disease affecting the hands and feet, especially the fingertips and toes. The pathogenic mechanisms of ACH have not been fully elucidated. Read More
Ticks Tick Borne Dis 2019 Jan 26;10(1):180-185. Epub 2018 Oct 26.
Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia. Electronic address:
Acrodermatitis chronica atrophicans is a late manifestation of European Lyme borreliosis and is characterized by high levels of borrelial IgG antibodies, slowly expanding skin redness usually beginning on distal parts of extremities, and corresponding histologic findings. It very rarely develops in children. The main prerequisite for the diagnosis is clinical suspicion. Read More
Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1199-1202
Department of Dermatology, Jaslok Hospital and Research Center, Mumbai, Maharashtra, India.
Zinc deficiency is an uncommon condition, known to occur in two forms: inherited type, known as Acrodermatitis enteropathies and the acquired type. Cutaneous clinical manifestations observed include characteristic dermatitis on acral, periorificial, and anogenital areas through an unknown mechanism. The patient had a combination of causes which lead to a state of zinc deficiency. Read More
JAMA Dermatol 2018 Nov;154(11):1346
Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus.
J Dermatolog Treat 2018 Sep 22:1-7. Epub 2018 Sep 22.
a Division of Dermatology , S. Chiara Hospital , Trento , Italy.
Acrodermatitis continua of Hallopeau is considered an uncommon variant of pustular psoriasis, characterised by a relapsing, sterile, pustular eruption of hands and feet. It is not easily treated by anti-psoriatic therapies, and may progress toward sclerosis and osteolysis. Numerous topical and systemic treatments have been used, with inconsistent results. Read More
JAAD Case Rep 2018 Sep 19;4(8):842-844. Epub 2018 Sep 19.
Dermatology Department, Hospital Universitario de La Princesa, Madrid, Spain.
Rheumatology (Oxford) 2018 Sep 19. Epub 2018 Sep 19.
Dermatology Department, and Université Paris Diderot-Paris VII, Sorbonne Paris Cité APHP, Saint-Louis Hospital, Paris, France.
Dermatol Res Pract 2018 7;2018:1284568. Epub 2018 Aug 7.
Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield S10 2RX, UK.
We report a family from Tabuk, Saudi Arabia, previously screened for Acrodermatitis Enteropathica (AE), in which two siblings presented with typical features of acral dermatitis and a pustular eruption but differing severity. Affected members of our family carry a rare genetic variant, p.Gly512Trp in the SLC39A4 gene which encodes a zinc transporter; disease is thought to result from zinc deficiency. Read More
Dermatol Online J 2018 May 15;24(5). Epub 2018 May 15.
Department of Dermatology, University of California, Davis, California.
The original article was published on July19, 2017 and corrected on May 15, 2018. The revised version of the article includes a funding source for Dr. Maija Kiuru's participation in this case report, awarded by the National Cancer Institute, National Institutes of Health grant K12CA138464. Read More
Cutis 2018 Jun;101(6):450-453
Department of Dermatology, University of Maryland School of Medicine, Baltimore, USA.
Acrodermatitis enteropathica (AE) is a rare autosomal-recessive disorder of zinc malabsorption, characterized by acral and periorificial dermatitis, alopecia, and diarrhea. Acquired AE is the result of decreased zinc intake, excessive zinc loss, or other malabsorptive processes. We present a case of a 54-year-old woman who developed characteristic skin lesions of acquired AE after zinc supplementation was removed from her total parenteral nutrition (TPN) solution. Read More
J Allergy Clin Immunol 2018 Jul 21. Epub 2018 Jul 21.
Department of Medical and Molecular Genetics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom.
Background: The term pustular psoriasis indicates a group of severe skin disorders characterized by eruptions of neutrophil-filled pustules. The disease, which often manifests with concurrent psoriasis vulgaris, can have an acute systemic (generalized pustular psoriasis [GPP]) or chronic localized (palmoplantar pustulosis [PPP] and acrodermatitis continua of Hallopeau [ACH]) presentation. Although mutations have been uncovered in IL36RN and AP1S3, the rarity of the disease has hindered the study of genotype-phenotype correlations. Read More
Skinmed 2018 1;16(3):205-207. Epub 2018 Jun 1.
Department of Pathology, University College of Medical Sciences, and Associated Guru Teg Bahadur Hospital, Shahdara, Delhi, India.
A 6-month-old, 4-kg, dehydrated girl, an Indian native, was admitted with recurrent episodes of diarrhea that had occurred since age 2 months. She had stopped breastfeeding. She had also had concomitant vomiting and loss of appetite. Read More
J Dtsch Dermatol Ges 2018 Jul;16(7):907-910
Klinik für Dermatologie und Allergologie, Technische Universität München, Deutschland.
J Dtsch Dermatol Ges 2018 Jul 21;16(7):907-910. Epub 2018 Jun 21.
Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
Pediatr Neonatol 2018 May 26. Epub 2018 May 26.
Metro Health Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Clin Case Rep 2018 Jun 14;6(6):1048-1050. Epub 2018 Apr 14.
Pediatric Department Hospital of Divino Espirito Santo of Ponta Delgada, EPER São Miguel Island, Azores Portugal.
Methylmalonic aciduria children must follow an adequate diet with low protein intake and should be regularly monitored to prevent complications. Although skin lesions like acrodermatitis enteropathica are rare in this disease, their appearance should be correlated with possible low plasma isoleucine level and it can be a sign of decompensation. Read More
Acta Dermatovenerol Croat 2018 Apr;26(1):68-70
Daniela Ledić Drvar, MD, PhD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;
Dear Editor, Pitted keratolysis (PK), also known as keratosis plantaris sulcatum, is a non-inflammatory, bacterial, superficial cutaneous infection, characterized by many discrete superficial crateriform ''pits'' and erosions in the thickly keratinized skin of the weight-bearing regions of the soles of the feet (1). The disease often goes unnoticed by the patient, but when it is noticed it is because of the unbearable malodor and hyperhidrosis of the feet, which are socially unacceptable and cause great anxiety to many of the patients. PK occurs worldwide, with the incidence rates varying based on the environment and occupation. Read More
J Dtsch Dermatol Ges 2018 May;16(5):610-612
Abteilung für Dermatologie, Krankenhaus San Pedro, Logroño, Spanien.
Arch Dis Child 2018 May 4. Epub 2018 May 4.
Pediatric Dermatology, Hospital de Clinicas - UFPR, Curitiba, Brazil.
An Bras Dermatol 2018 Mar;93(2):285-287
Department of Dermatology and Radiotherapy, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil.
Pigeon lice are insects that feed on feathers of these birds; their life cycle includes egg, nymph and adult and they may cause dermatoses in humans. Four persons of the same family, living in an urban area, presented with widespread intensely pruritic erythematous papules. A great number of lice were seen in their house, which moved from a nest of pigeons located on the condenser of the air-conditioning to the dormitory of one of the patients. Read More
An Bras Dermatol 2018 Mar;93(2):265-267
Outpatient Clinic of Pediatric Dermatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
We report the case of a male 22-month-old child, with atypical presentation of Gianotti-Crosti syndrome after infection with Epstein-Barr virus. Read More
Dermatol Ther 2018 May 25;31(3):e12595. Epub 2018 Apr 25.
Department of Dermatology, the Affiliated Hospital of Jiangsu University, Zhenjiang, China.
JAAD Case Rep 2018 Apr 7;4(3):277. Epub 2018 Mar 7.
Department of Dermatology, St James's Hospital Dublin, Dublin, Ireland.
J Dtsch Dermatol Ges 2018 May 16;16(5):611-613. Epub 2018 Apr 16.
Department of Dermatology, Hospital San Pedro, Logroño, Spain.
Dtsch Med Wochenschr 2018 Apr 12;143(8):549-550. Epub 2018 Apr 12.
Klinik für Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Krankenhaus Oberhausen, Universität Witten-Herdecke.
J Pediatr 2018 Jul 5;198:320. Epub 2018 Apr 5.
Allergy Immunology Unit Department of Pediatrics Advanced Pediatrics Center Postgraduate Institute of Medical Education and Research Chandigarh, India.
J Eur Acad Dermatol Venereol 2018 Oct 11;32(10):1645-1651. Epub 2018 Apr 11.
Department of Dermatology, Rutgers-New Jersey Medical School, Newark, NJ, USA.
Generalized pustular psoriasis (GPP) is a subtype of pustular psoriasis characterized by painful and occasionally disfiguring cutaneous manifestations with sepsis-like systemic symptoms. Affecting any age and race, GPP can occur with other forms of psoriasis or by itself. Stimuli for flares include medications, infections and environmental triggers. Read More
PLoS Genet 2018 03 22;14(3):e1007264. Epub 2018 Mar 22.
Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Lethal acrodermatitis (LAD) is a genodermatosis with monogenic autosomal recessive inheritance in Bull Terriers and Miniature Bull Terriers. The LAD phenotype is characterized by poor growth, immune deficiency, and skin lesions, especially at the paws. Utilizing a combination of genome wide association study and haplotype analysis, we mapped the LAD locus to a critical interval of ~1. Read More
Dermatol Online J 2017 Jul 15;23(7). Epub 2017 Jul 15.
Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York. vsharon@ northwell.edu.
Acquired zinc deficiency can develop as a consequence of poor nutritional intake or from dependence on total parenteral nutrition. Acquired zinc deficiency dermatitis classically manifests with erosions and scaly plaques in a periorificial and acral distribution. We present a case of a woman on parenteral nutrition who presented with bullous acrodermatitis mimicking pemphigus foliaceus histopathologically. Read More
Nutrients 2018 Feb 16;10(2). Epub 2018 Feb 16.
Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan.
The first manifestations that appear under zinc deficiency are skin defects such as dermatitis, alopecia, acne, eczema, dry, and scaling skin. Several genetic disorders including acrodermatitis enteropathica (also known as Danbolt-Closs syndrome) and Brandt's syndrome are highly related to zinc deficiency. However, the zinc-related molecular mechanisms underlying normal skin development and homeostasis, as well as the mechanism by which disturbed zinc homeostasis causes such skin disorders, are unknown. Read More
Nutrients 2018 Feb 11;10(2). Epub 2018 Feb 11.
Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types of cells. Firstly, we review the physiological functions of Zn and Zn transporters in these cells. Read More
Case Rep Dermatol 2017 Sep-Dec;9(3):259-264. Epub 2017 Dec 18.
Department of Dermatology, King Saud University Medical City, Riyadh, Saudi Arabia.
Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. Read More
J Dermatol Sci 2018 May 1;90(2):105-111. Epub 2018 Feb 1.
Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Classifying inflammatory skin diseases is challenging, especially for the expanding group of disorders triggered by genetic factors resulting in hyperactivated innate immunity that result in overlapping patterns of dermal and epidermal inflammation with hyperkeratosis. For such conditions, the umbrella term "autoinflammatory keratinization diseases" (AIKD) has been proposed. AIKD encompasses diseases with mixed pathomechanisms of autoinflammation and autoimmunity, and includes IL-36 receptor antagonist (IL-36Ra)-related pustulosis, CARD14-mediated pustular psoriasis, pityriasis rubra pilaris (PRP) type V, and familial keratosis lichenoides chronica (KLC). Read More
Rev Paul Pediatr 2018 Apr-Jun;36(2):238-241. Epub 2018 Jan 15.
Universidade de São Paulo, Ribeirão Preto, São Paulo, Brasil.
Objective: To report a case of acrodermatitis enteropathica, a rare disease with autosomal recessive inheritance.
Case Description: An 11-month-old boy was presenting symmetrical erythematous and yellowish-brownish crusted lesions on his face, feet, hands and knees, intermittent diarrhea, fever, and recurrent infections since the age of six months. He was thin and had scarce hair on the scalp. Read More
Psoriasis (Auckl) 2017 16;7:51-63. Epub 2017 Oct 16.
Department of Dermatology, Inselspital, University of Bern, Bern, Switzerland.
Psoriasis is the skin disease that most frequently affects the nails. Depending on the very nail structure involved, different clinical nail alterations can be observed. Irritation of the apical matrix results in psoriatic pits, mid-matrix involvement may cause leukonychia, whole matrix affection may lead to red lunulae or severe nail dystrophy, nail bed involvement may cause salmon spots, subungual hyperkeratosis, and splinter hemorrhages, and psoriasis of the distal nail bed and hyponychium causes onycholysis whereas that of the proximal nail fold causes psoriatic paronychia. Read More
Bol Med Hosp Infant Mex 2017 Jul - Aug;74(4):295-300. Epub 2017 Jul 5.
Servicio de Infectología Pediátrica, Centro Médico Nacional 20 de Noviembre, ISSSTE, Ciudad de México, México.
Introduction: Acrodermatitis enteropathica is a low-incidence disease due to inherited or acquired zinc deficiency. It is characterized by acral dermatitis, alopecia, diarrhea and growth retardation. The dermatological condition may mimic a cutaneous fungal infection or other pathogen-related skin diseases. Read More
Transl Sci Rare Dis 2017 Dec 18;2(3-4):101-139. Epub 2017 Dec 18.
Section on Human Biochemical Genetics, Medical Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA.
Trace elements are chemical elements needed in minute amounts for normal physiology. Some of the physiologically relevant trace elements include iodine, copper, iron, manganese, zinc, selenium, cobalt and molybdenum. Of these, some are metals, and in particular, transition metals. Read More
Clin Exp Dermatol 2018 Apr 15;43(3):315-318. Epub 2018 Jan 15.
Department of Dermatology, St George's Healthcare NHS Trust, London, UK.
Methylmalonic acidaemia (MMA) is an inborn error of amino acid metabolism that may be associated with cutaneous manifestations mimicking other diagnoses, including staphylococcal scalded skin syndrome (SSSS), psoriasis and acrodermatitis enteropathica. Whether this is due to the underlying metabolic disorder itself or occurs as a consequence of dietary restriction has yet to be elucidated. Skin biopsies typically show histological features shared by a number of other metabolic disorders and nutritional deficiency-associated diseases. Read More
Br J Dermatol 2018 Mar 15;178(3):614-618. Epub 2018 Jan 15.
Department of Dermatology, AP-HP Hôpital Saint-Louis, 1 Avenue Claude Vellefaux, Paris CEDEX 10, 75475, France.
Patients with pustular psoriasis or related pustular diseases may have genetic abnormalities impairing the function of key players of the innate skin immune system. Recently, identification of these abnormalities has changed the paradigm of several of these diseases. These include generalized pustular psoriasis, palmoplantar pustular psoriasis and acrodermatitis continua of Hallopeau, and also drug-induced acute exanthematous generalized pustular eruption. Read More
BMJ 2018 01 11;360:j5547. Epub 2018 Jan 11.
St John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK.
J Cutan Pathol 2018 Apr 9;45(4):274-277. Epub 2018 Feb 9.
Departments of Dermatology and Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Lyme disease classically evolves through clinical manifestations according to the stage of illness. Because many of the systemic symptoms are non-specific, and because serology may yield false negative results, cutaneous findings merit even greater importance to diagnosis. The prototypical skin lesion, erythema migrans (EM), occurs early and is the only independent diagnostic clinical feature according to the guidelines of the Infectious Diseases Society of America. Read More
Am J Dermatopathol 2018 May;40(5):367-370
Department of Dermatology, Medical University of Graz, Graz, Austria.
Acrodermatitis chronica atrophicans (ACA) that is characterized by thin, papery dry, translucent, and alopecic patches with visible superficial veins is a late cutaneous manifestation of Lyme borreliosis. Clinical findings, a history of exposure to tick bite, and serology are helpful for the diagnosis of ACA and sometimes a biopsy is performed to rule out other infectious or inflammatory processes. In this study, we report reflectance confocal microscopy (RCM) findings in a case of ACA. Read More
Cutis 2017 11;100(5):E4-E6
Division of Dermatology, David Geffen School of Medicine, University of California Los Angeles, USA.
Case Rep Dermatol Med 2017 25;2017:3905658. Epub 2017 Oct 25.
Division of Nutrition, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Introduction: Maple syrup urine disease (MSUD) is an inborn error of branched chain amino acids (BCAAs) metabolism. We report an infant with MSUD who developed 2 episodes of cutaneous lesions as a result of isoleucine deficiency and zinc deficiency, respectively.
Case Presentation: A 12-day-old male infant was presented with poor milk intake and lethargy. Read More
Skin Appendage Disord 2017 Oct 29;3(4):179-181. Epub 2017 Apr 29.
Department of Dermatology, St George Hospital, and University of New South Wales, Sydney, NSW, Australia.
Cureus 2017 Sep 8;9(9):e1667. Epub 2017 Sep 8.
Internal Medicine, University of Central Florida College of Medicine.
We present a case of severe acquired acrodermatitis enteropathica in a vegan adult female with multiple underlying comorbidities. Acquired acrodermatitis enteropathica or zinc-deficiency dermatitis is the most common diagnosis than many practitioners realize with up to 10% of the patients in developed nations with the risk of zinc deficiency. The condition can be difficult to diagnose due to many similarly-presenting conditions. Read More
J Dermatolog Treat 2018 Jun 9;29(4):353-363. Epub 2017 Nov 9.
c Institute of Dermatology , Guangzhou Medical University , Guangzhou , P.R. China.
Background: There is a few evidence-based information regarding the efficacy and safety of acitretin treatment in children with pustular psoriasis (PP).
Objective: This study aimed to provide an additional evidence for this field.
Methods: A retrospective study was undertaken for 15 children with PP who received acitretin in doses of 0. Read More
J Dermatol 2018 Feb 23;45(2):e41-e42. Epub 2017 Oct 23.
Department of Dermatology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ger Med Sci 2017 5;15:Doc14. Epub 2017 Sep 5.
Klinik für Infektiologie Klinik St Georg, Leipzig, Germany.
This guideline of the German Dermatology Society primarily focuses on the diagnosis and treatment of cutaneous manifestations of Lyme borreliosis. It has received consensus from 22 German medical societies and 2 German patient organisations. It is the first part of an AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e. Read More