Search Our Scientific Publications & Authors

PLoS One 2022 6;17(6):e0269358. Epub 2022 Jun 6.

Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

Background: Birt-Hogg-Dubé (BHD) syndrome is an ultrarare lung disease with unclear prevalence and incidence. Our study aimed to identify the epidemiological and clinical features of BHD syndrome by using nationwide claims data from the Korean Health Insurance Review and Assessment service.

Methods: Patients with BHD syndrome who had the following criteria were included: 1) tested for folliculin gene mutation, and 2) had at least one of the conditions: other specified malformation syndromes, fibrofolliculoma, acrochordon, lung cyst, cancer, and pneumothorax based on International Classification of Disease-10 code. Read More

Pediatr Dermatol 2022 Mar 14. Epub 2022 Mar 14.

Department of Dermatology, Aydın Adnan Menderes University Faculty of Medicine, Aydın, Turkey.

Background: Cutaneous changes in obese adults have been investigated in numerous studies, but this issue has not been adequately investigated in children.

Objectives: We aimed to determine the prevalence of skin manifestations in children with obesity by comparing them to normal-weight children.

Methods: A cross-sectional study was conducted between June 2017 and January 2019 in which 82 children with obesity and 86 normal-weight healthy control children were enrolled. Read More

JNMA J Nepal Med Assoc 2021 Nov 15;59(243):1106-1110. Epub 2021 Nov 15.

Department of Pathology, Manipal Teaching Hospital, Pokhara, Nepal.

Introduction: Skin tumors are relatively uncommon malignancies worldwide, but its incidence has been progressively increased over the last few decades. Skin tumor belongs to a diverse group of neoplasms arising from the epidermis, adnexal structures and dermis rendering the classification difficult. The study aims to find out the prevalence of benign skin neoplasm among the histopathological specimens of skin neoplasm of a teaching hospital. Read More

Int J Clin Pract 2021 Oct 8;75(10):e14687. Epub 2021 Aug 8.

Department of Public Health, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

Aim: In the literature, there are no data examining the association with lichen planus with acanthosis nigricans and acrochordon, which are skin findings of metabolic syndrome (MS).

Materials: A total of 108 lichen planus (LP) patients, age and sex-matched 109 controls, 217 patients in total were prospectively included in the study.

Results: Metabolic Syndrome was found in 55 (50. Read More

Pathogens 2021 Apr 30;10(5). Epub 2021 Apr 30.

Institute of Pathology, Wild Animals, Fish and Bees, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000 Ljubljana, Slovenia.

Papillomaviruses (PVs) are an extremely large group of viruses that cause skin and mucosal infections in humans and various domestic and wild animals. Nevertheless, there is limited knowledge about PVs in wildlife hosts, including mustelid species. This study describes a case in stone marten () with a clinical manifestation of skin tumor, which is rather atypical for infections with PVs. Read More

Cureus 2021 Feb 25;13(2):e13554. Epub 2021 Feb 25.

Department of Dermatology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare cutaneous hamartoma characterized by mature adipocytes in the dermis. Here, we present a unique case of NLCS in a 57-year-old female that strikingly resembled an acrochordon, demonstrating features of the classical and solitary form of NLCS. This presentation of NLCS has not been widely reported and emphasizes that the diagnosis of NLCS should be considered when evaluating suspected acrochordons. Read More

J Clin Aesthet Dermatol 2020 Dec 1;13(12):32-37. Epub 2020 Dec 1.

Ms. Coakley, Mr. Wu, Mr. Kumar, and Ms. Dadrass are with Loyola University Chicago Stritch School of Medicine at Loyola University Medical Center in Maywood, Illinois.

Acrochordon (skin tag) removal by snip excision is a routine dermatologic procedure. Bleeding is a common sequelae of snip excision that requires hemostatic control. Chemical cautery is a common means of achieving hemostasis in this procedure. Read More

BMC Dermatol 2020 11 3;20(1):14. Epub 2020 Nov 3.

Dermatology and Venereology Department, Akdeniz University School of Medicine, Antalya, Turkey.

Background: There are reports that acrochordon (skin tag), the most common fibroepithelial tumor of the skin, may be associated with metabolic syndrome components, particularly insulin metabolism disorders. However, to the best of our knowledge, there is no study examining its association with insulin resistance and tissue levels of insulin-like growth factor 1 receptor (IGF-1R) and insulin-like growth factor 2 receptor (IGF-2R).

Methods: Thirty patients with at least one acrochordon in their body who had no known history of diabetes mellitus and a control group comprised 30 individuals who had no acrochordon or no known history of diabetes mellitus were included. Read More

Skin Res Technol 2021 May 11;27(3):324-331. Epub 2020 Oct 11.

Department of Dermatology, Bispebjerg and Frederiksberg, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Skin tags are common and mostly benign, but occasionally contain skin cancers. This study analysed skin tags by combining three advanced optical imaging technologies: reflectance confocal microscopy (RCM), optical coherence tomography (OCT) and multispectral optoacoustic imaging (MSOT) supplemented by dermoscopy MATERIALS AND METHODS: A prospective clinical study recruiting patients with skin tags from a university hospital clinic over a 2-week period. OCT, RCM and MSOT imaging were performed prior to excisional biopsies. Read More

Hum Antibodies 2020 ;28(4):335-339

Department of Gynecology and Obstetrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Background: Acrochordons are benign hypertrophic lesions of the skin of which the pathophysiology is unclear.

Objective: This study aimed to examine the association of acrochordons with autoimmune disorders in patients with a poor obstetric history.

Methods: This retrospective cohort involved 350 female patients with poor obstetric history who were included in a preconceptional care program to investigate risk factors for obstetric complications. Read More

Sisli Etfal Hastan Tip Bul 2020 27;54(2):257-260. Epub 2020 May 27.

Department of Pathology, Balıkesir Atatürk City Hospital, Balıkesir, Turkey.

Fibroepithelial polyps (acrochordon or skin tag) are benign tumors that usually occur in skin folds, such as the axilla, genital area or neck. They can be solitary or multiple. Their dimensions usually do not exceed 1-2 millimeters. Read More

Indian J Dermatol 2020 Mar-Apr;65(2):112-117

Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Background: Insulin resistance (IR) is a pre-diabetic condition and has been reported in patients with acanthosis nigricans (AN) and acrochordon. AN and acrochordon are claimed to be cutaneous markers of IR.

Aim: The purpose of this paper was to study the association of AN and acrochordon with IR. Read More

Open Access Maced J Med Sci 2019 Sep 31;7(18):2988-2990. Epub 2019 May 31.

Department of Dermatology, University of Rome "G. Marconi", Rome, Italy.

Background: Eccrine poroma is a benign tumour of eccrine duct epithelium. The usual clinical presentation is nodular.

Case Report: We present a 78-year-old man with a painful pendulating flesh-coloured malodorous plantar tumour. Read More

Postgrad Med J 2020 Apr 13;96(1134):237. Epub 2019 Oct 13.

Endocrinology and Diabetes, St. Joseph - St. Luc Hospital, Lyon, France.

Dermatol Clin 2019 Oct 10;37(4):545-554. Epub 2019 Jul 10.

Department of Dermatology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Ezralow Tower, Suite 5301, Los Angeles, CA 90033-9174, USA. Electronic address:

Cutaneous metastasis portends a poor prognosis. Therefore, a high clinical index of suspicion is necessary so that a clinician knows how to recognize the presentation of a cutaneous metastasis, while the pathologist must know the appropriate stains to order. In this review, the authors summarize the common and uncommon ways that these tumors will present. Read More

Acta Dermatovenerol Croat 2019 Jun;27(2):127-128

Dr. Jorge Ocampo-Candiani, Chair of the Dermatology Department, University Hospital "Dr. José E. González", Universidad Autónoma de Nuevo León, Mitras Centro, Avenida Gonzalitos y Madero S/N, 64460 Monterrey, Mexico;

Dear Editor, Acrochordons are common benign neoplasms found in everyday practice. We present a rare case of a giant and single acrochordon on the lumbar region with signs of ischemia. The correlation of clinical, dermatoscopic, and histopathological analyses may help the clinician differentiate this entity from other benign and malignant dermatoses. Read More

Am J Dermatopathol 2019 Jun;41(6):e64-e65

Section of Dermatology, Department of Medicine, University of Chicago, Chicago, IL.

Lichen sclerosus (LS) is a chronic inflammatory dermatosis that classically presents as sclerotic, atrophic plaques in the genital region. We present a case of acrochordon with histological features of LS, clinically mimicking intradermal nevus, in a 53-year-old man with no prior history of LS. Our case highlights an unusual morphologic variant of acrochordon and illustrates the role of chronic pressure and occlusion in the development of secondary features of LS. Read More

North Clin Istanb 2018 21;5(2):114-119. Epub 2018 May 21.

Department of Dermatology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

Objective: Obesity is known to be a risk factor for many diseases including dermatological problems. Here, we aimed to determine the cutaneous manifestations in obese patients and the frequency of the accompanying dermatoses and to investigate the effect of diabetes mellitus in obese patients on cutaneous manifestations compared with the control group.

Methods: Our study included a total of 600 adults: 450 obese volunteers and 150 healthy volunteers. Read More

BMC Med Genet 2018 01 22;19(1):14. Epub 2018 Jan 22.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Background: Birt-Hogg-Dubé syndrome is an autosomal dominant hereditary condition caused by mutations in the folliculin-encoding gene FLCN (NM_144997). It is associated with skin lesions such as fibrofolliculoma, acrochordon and trichodiscoma; pulmonary lesions including spontaneous pneumothorax and pulmonary cysts and renal cancer.

Methods: Genomic DNA was extracted from peripheral venous blood samples of the propositi and their family members. Read More

Clin Dermatol 2018 Jan - Feb;36(1):81-88. Epub 2017 Sep 8.

Department of Dermatology, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.

The cutaneous manifestations of obesity and the associated metabolic syndrome (MetS) may present with a wide variety of cutaneous findings, including acanthosis nigricans, acrochordon, cellulitis, psoriasis, hidradenitis suppurativa, acne, and hirsutism. Being aware of such clinical signs and the underlying systemic disorders may facilitate earlier diagnoses, thereby permitting earlier of therapy initiation and prevention of long-term sequelae. In this process, dermatologists are key figures in the early detection of MetS and its clinical manifestations. Read More

Clin Nucl Med 2017 Jun;42(6):461-462

From the Departments of *Nuclear Medicine, and †Dermatology, Kocaeli University School of Medicine, Kocaeli, Turkey.

Ga prostate-specific membrane antigen (PSMA) PET/CT is a promising tool for imaging of prostate cancer. Ga-PSMA PET/CT uptake of prostate cancer and its metastases are reflective of significant overexpression of PSMA. However, PSMA expression of benign neoplasms and nonprostate epithelial malignancies is not very well defined. Read More

Indian Dermatol Online J 2016 Sep-Oct;7(5):390-392

Department of Pathology, University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

Granular cell tumors (GCTs) are uncommon soft tissue tumors which present as papulonodular lesions and are often diagnosed histopathologically. These usually develop in adulthood and are considered to be of Schwann cell origin. Most of the lesions are benign, but malignant lesions with poor prognosis are known to occur. Read More

Med J Armed Forces India 2016 Jan 22;72(1):67-70. Epub 2014 Nov 22.

Professor & Head, Army College of Medical Sciences, New Delhi, India; Consultant (Pathology), Base Hospital, Delhi Cantt, India.

Background: Nevus Lipomatosis Cutaneous Superficialis (NLCS) is a rare, benign hamartomatous lesion characterized by the ectopic presence of mature adipocytes in the reticular dermis not associated with the underlying subcutaneous tissue. Two clinical forms-classical and solitary occur. The solitary form is relatively uncommon, due to which these lesions are commonly clinically misdiagnosed. Read More

J Clin Diagn Res 2016 Jan 1;10(1):BC09-11. Epub 2016 Jan 1.

Assistant Professor, Department of Dermatology, M R Medical College , Kalaburgi, India .

Introdction: Acrochordon or fibroepithelial polyp, commonly known as Skin tags (STs) are one of the most common benign skin condition, consisting of skin projecting from the surrounding skin, usually occurring on the eyelids, neck and axillae. Studies have found an association of STs with conditions such as obesity, diabetes mellitus and atherogenic lipid profile. Abdominal obesity and the consequent insulin resistance are said be important contributing factors for diabetes, dyslipidaemia and cardiovascular disease. Read More

Indian Dermatol Online J 2015 Nov-Dec;6(6):436-8

Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.

J Coll Physicians Surg Pak 2015 Nov;25(11):839-40

Department of Surgery, Diyarbakir Education and Research Hospital, 21400, Diyarbakir, Turkey.

Acrochordons commonly develop from skin on the neck and axillar region, but may be found on any region of body. Although some predisposing factors have been implicated, the definite etiology has yet to be determined. We report the case of a 46-year female patient who presented with a large mass lesion on the inner aspect of the thigh. Read More

J Am Podiatr Med Assoc 2015 Sep;105(5):440-2

We report on a 63-year-old male who was found to have an acrochordon on his plantar foot. Although acrochordons constitute a common benign clinical finding, this observation represents, to our knowledge, only the second case reported on the foot and the first occuring on the plantar surface. Read More