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Acoust Phys 2016 Jul 22;62(4):514-522. Epub 2016 Jul 22.

Appalachian State University, Boone, NC, 28608-2071, USA.

An acoustical handheld hydration monitor (HM) for assessing the water balance of the human body was developed. Dehydration is a critical public health problem. Many elderly over age of 65 are particularly vulnerable as are infants and young children. Read More

Acoust Phys 2011 May;57(3):334-343

Moscow State University, Moscow, 119991, Russia.

A novel numerical model was developed to simulate three-dimensional nonlinear fields generated by high intensity focused ultrasound (HIFU) arrays. The model is based on the solution to the Westervelt equation; the developed algorithm makes it possible to model nonlinear pressure fields of periodic waves in the presence of shock fronts localized near the focus. The role of nonlinear effects in a focused beam of a two-dimensional array was investigated in a numerical experiment in water. Read More

Acoust Phys 2010 Sep;56(5):665-674

Department of Acoustics, Physics Faculty, Moscow State University, Leninskie gory, Moscow, 119991 Russia.

The effect of focus splitting after propagation of focused ultrasound through a rib cage is investigated theoretically. It is shown that the mechanism of this effect is caused by the interference of waves from two or more spatially separated sources, such as intercostal spaces. Analytical estimates of the parameters of splitting are obtained, i. Read More

Acoust Phys 2010 Jan;56(3):354-363

Department of Acoustics, Physics Faculty, Moscow State University, Leninskie gory, Moscow, 119991, Russia, ,

Current methods of determining high intensity focused ultrasound (HIFU) fields in tissue rely on extrapolation of measurements in water assuming linear wave propagation both in water and in tissue. Neglecting nonlinear propagation effects in the derating process can result in significant errors. In this work, a new method based on scaling the source amplitude is introduced to estimate focal parameters of nonlinear HIFU fields in tissue. Read More

Acoust Phys 2009 Jul;55(4-5):647-656

ProRhythm, 105 Comac Street, Ronkonkoma, NY 11779, USA.

The application of therapeutic ultrasound for the treatment of atrial fibrillation (AF) is investigated. The results of theoretical and experimental investigation of ultrasound ablation catheter are presented. The major components of the catheter are the high power cylindrical piezoelectric element and parabolic balloon reflector. Read More

Acoust Phys 2009 Jul;55(4-5):463-476

Department of Acoustics, Physics Faculty, Moscow State University, Leninskie gory, Moscow, 119992, Russia.

In this work, the influence of nonlinear and diffraction effects on amplification factors of focused ultrasound systems is investigated. The limiting values of acoustic field parameters obtained by focusing of high power ultrasound are studied. The Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation was used for the numerical modeling. Read More

Acoust Phys 2009 Oct;55(4-5):594-601

Department of Bioengineering, University of Utah, USA.

The article describes the study of targeted chemotherapeutic intervention on solid tumors by means of ultrasound and doxorubicin- or paclitaxel-loaded perfluoropentane nanoemulsions. Nanodroplets of the emulsions accumulated in a tumor by passive targeting. Under the action of a tumor-directed therapeutic ultrasound, the nanodroplets converted into vapor microbubbles. Read More