13,479 results match your criteria Acneiform Eruptions

An epidemiological study on face masks and acne in a Nigerian population.

PLoS One 2022 19;17(5):e0268224. Epub 2022 May 19.

Dermatology Unit Department of Internal Medicine, National Hospital Abuja, Abuja, Nigeria.

Background: Acne vulgaris is a skin disorder that affects males and females with significant impact on quality of life. The onset of the COVID-19 pandemic led to a series of non-pharmaceutical interventions globally to reduce the spread of the virus particularly since there have been no known cures or definitive treatment for the disease. One key non-pharmaceutical intervention was recommendation on wearing of face masks. Read More

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Hormonal Intrauterine Devices and Acne.

Obstet Gynecol 2022 May 5;139(5):919-921. Epub 2022 Apr 5.

Boston University School of Medicine and the Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; and the Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana.

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Can Extracts from the Leaves and Fruits of the Species Be Considered Promising Anti-Acne Agents?

Molecules 2022 May 2;27(9). Epub 2022 May 2.

Department of Pharmaceutical Botany, Medical University of Lublin, 20-093 Lublin, Poland.

This study aimed to evaluate the phenolic profile and biological activity of the extracts from the leaves and fruits of and . Considering that miscellaneous species of are thought to be healing in traditional Asian medicine, we assumed that this uninvestigated species may reveal significant therapeutic properties. Here, we report the simultaneous assessment of chemical composition as well as biological activities (antioxidant, anti-inflammatory, antibacterial, and cytotoxic properties) of tested species. Read More

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Contact Allergy in Patients with Rosacea.

Actas Dermosifiliogr 2022 May 10. Epub 2022 May 10.

Servicio de Dermatología, Hospital General Universitario de Valencia, Spain.

Background And Objective: Rosacea is a chronic acneiform skin disorder in which impaired skin barrier function can lead to sensitization to allergens. We aimed to analyze contact allergies in our patients with rosacea.

Material And Methods: Retrospective cohort study of all patients who underwent patch testing in our skin allergy clinic between May 1991 and May 2019. Read More

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[Clinical Observation of Recombinant Bovine Basic Fibroblast Growth Factor as an Adjuvant Therapy for Patients with Atrophic Acne Scar].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2022 Apr;44(2):208-212

Department of Medical Cosmetology,Xinyang Central Hospital,Xinyang,Henan 464000,China.

Objective To study the influence of recombinant bovine basic fibroblast growth factor as an adjuvant therapy on scar alleviation and inflammatory cytokines in patients with atrophic acne scar. Methods The random number table was employed to randomly assign 120 patients with atrophic acne scar into a test group and a control group.Both groups of patients were treated with CO lattice laser. Read More

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Sarecycline: A Narrow-Spectrum Antibiotic.

Skin Therapy Lett 2022 May;27(3):5-7

Center for Clinical Studies, Webster, TX, USA.

Tetracycline-class drugs have been used for first-line treatment of moderate-to-severe acne and rosacea for decades. Recently, a new third generation tetracycline, sarecycline, was US FDA-approved for the treatment of moderate-to-severe acne. This narrow-spectrum tetracycline-derived antibiotic has been shown to be effective with an improved safety profile. Read More

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Significant and Sustained Response with Short Cycle of Low-Dose Isotretinoin in Morbihan Disease.

Skinmed 2022 30;20(2):157-158. Epub 2022 Apr 30.

Pathological Anatomy Department, Hospital de Santarém EPE, Santarém, Portugal.

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[Preparation of tanshinone Ⅱ_A-glycyrrhetinic acid solid lipid nanoparticles and its inhibitory effect on acne].

Zhongguo Zhong Yao Za Zhi 2022 May;47(9):2449-2456

Guizhou University of Traditional Chinese Medicine Guiyang 550001, China.

The optimal prescription of tanshinone Ⅱ_A(TSN)-glycyrrhetinic acid(GA) solid lipid nanoparticles(GT-SLNs) was explored and evaluated in vivo and in vitro, and its effect on acne after oral administration was investigated. The preparation processing and prescription were optimized and verified by single factor and response surface methodology. The in vitro release of GA and TSN in GT-SLNs was determined by ultra-performance liquid chromatography(UPLC). Read More

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Perifollicular Xanthoma Occurring in Patients after Erlotinib Treatment.

Dermatol Ther (Heidelb) 2022 May 4;12(5):1281-1286. Epub 2022 May 4.

Department of Dermatology, College of Medicine, Chungbuk National University, Chungdae-ro 1, Seowon-Gu, Cheongju, Chungbuk, 28644, South Korea.

Erlotinib (Tarceva) is a drug used for the treatment of non-small cell lung cancer in patients with epidermal growth factor receptor (EGFR) mutations. Since EGFR is expressed in the skin, EGFR inhibitors commonly develop cutaneous side effects such as acneiform eruption, paronychia, telangiectasias, and abnormal eyelash growth. A 56-year-old man and a 46-year-old man visited the dermatology clinic complaining of yellowish papuloplaques and acneiform eruption on the face. Read More

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[ACNES syndrome, exploring the abdominal wall as source of abdominal pain].

Andes Pediatr 2022 Feb 28;93(1):86-92. Epub 2022 Mar 28.

Hospital Universitario Fundación Alcorcón, Madrid, España.

Abdominal wall pain, specifically ACNES syndrome (Anterior Cutaneous Nerve Entrapment Syn drome), is part of the differential diagnosis of chronic abdominal pain. This syndrome is frequently overlooked and therefore underdiagnosed.

Objectives: To describe the clinical and evolutionary cha racteristics of patients diagnosed with ACNES and to draw attention to this pathology. Read More

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February 2022

Skin microbiome reconstruction and lipid metabolism profile alteration reveal the treatment mechanism of Cryptotanshinone in the acne rat.

Phytomedicine 2022 Jul 18;101:154101. Epub 2022 Apr 18.

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. Electronic address:

Background: Acne has become one of the most prevalent skin disorders, affecting mostly young people's physical and mental health globally. Cryptotanshinone (CPT) is a potential drug for acne, but its mechanism of acne treatment has not been thoroughly studied on the microbiota. Till date, only a few studies are directed to the impact of acne therapy on skin microbiota and lipid metabolites. Read More

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Acne and diet: a review of pathogenic mechanisms.

Bol Med Hosp Infant Mex 2022 ;79(2):83-90

Servicio de Dermatología Pediátrica, Hospital Infantil de México Federico Gómez, Mexico City.

Acne is a chronic inflammatory disease of the pilosebaceous unit with multifactorial etiology. Abnormal proliferation of keratinocytes, altered sebum production, inflammation of the sebaceous follicle, and colonization by Cutibacterium acnes have been traditionally implicated. However, the diet has also been highlighted in the pathogenesis because of its direct relation with some biochemical markers and the transcription of specific genes associated with sebaceous gland activity, inflammation, and bacterial proliferation, which together promote the development of the disease, affect the severity of the condition, and modify its response to treatment. Read More

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Prognostic Factors Determining Success in Acne Treatment-Part II: Treatment Factors.

Skinmed 2022 28;20(1):58-61. Epub 2022 Feb 28.

Department of Dermatology, Memorial Atasehir Hospital, Istanbul, Turkey.

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[Clinical efficacy of 585 nm Q-switched laser treatment on inflammatory lesion and postinflammatory erythema of acne vulgaris].

Beijing Da Xue Xue Bao Yi Xue Ban 2022 Apr;54(2):283-288

Department of Dermatology, Peking University First Hospital; National Clinical Research Center For Skin and Immune Diseases; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses; National Medical Products Administration Key Laboratory for Quality Control and Evaluation of Cosmetics, Beijing 100034, China.

Objective: To evaluate the efficacy and safety of 585 nm Q-switched laser in the treatment of acne inflammatory lesions and postinflammatory erythema.

Methods: A total of 25 patients with moderate facial acne, symmetrical distribution of inflammatory lesions and postinflammatory erythema on both sides of the face, were enrolled. Among the 25 patients, 22 patients completed all the treatment and evaluation, and 3 patients were lost to follow-up. Read More

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Female Pelvic Conditions: Polycystic Ovary Syndrome.

FP Essent 2022 04;515:26-31

Department of Family Medicine - University of California San Diego School of Medicine, 402 Dickinson St, San Diego, CA 92103.

It is estimated that polycystic ovary syndrome (PCOS) affects about 10% of women of reproductive age in the United States. Principal risk factors include obesity and a family history of PCOS. A diagnosis of PCOS should be considered in women with irregular or absent menstrual cycles, issues related to hyperandrogenism, or infertility. Read More

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BMAL1 regulates -induced skin inflammation via REV-ERBα in mice.

Int J Biol Sci 2022 21;18(6):2597-2608. Epub 2022 Mar 21.

Institute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese Medicine, Guangzhou, China.

Acne vulgaris is a common skin disease, affecting over 80% of adolescents. Inflammation is known to play a central role in acne development. Here, we aimed to investigate the role of the central clock gene in acne-associated inflammation in mice. Read More

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Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders.

Int J Mol Sci 2022 Mar 30;23(7). Epub 2022 Mar 30.

Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8549, USA.

Adipocytes from the superficial layer of subcutaneous adipose tissue undergo cyclic de- and re-differentiation, which can significantly influence the development of skin inflammation under different cutaneous conditions. This inflammation can be connected with local loading of the reticular dermis with lipids released due to de-differentiation of adipocytes during the catagen phase of the hair follicle cycle. Alternatively, the inflammation parallels a widespread release of cathelicidin, which typically takes place in the anagen phase (especially in the presence of pathogens). Read More

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Suppression of -Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin.

Int J Mol Sci 2022 Mar 25;23(7). Epub 2022 Mar 25.

School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325015, China.

() is a common commensal bacterium that is closely associated with the pathogenesis of acne. Fibroblast growth factor 21 (FGF21), as a favorable regulator of glucose and lipid metabolism and insulin sensitivity, was recently shown to exert anti-inflammatory effects. The role and mechanism of FGF21 in the inflammatory reactions induced by , however, have not been determined. Read More

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Prediction of Antibacterial Peptides against from the Peptidomes of Mucus Fractions.

Molecules 2022 Mar 31;27(7). Epub 2022 Mar 31.

Department of Zoology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.

Acne vulgaris is a common skin disease mainly caused by the Gram-positive pathogenic bacterium, . This bacterium stimulates the inflammation process in human sebaceous glands. The giant African snail () is an alien species that rapidly reproduces and seriously damages agricultural products in Thailand. Read More

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Effect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial.

Nutrients 2022 Mar 23;14(7). Epub 2022 Mar 23.

Department of Bromatology, Poznan University of Medical Sciences, 60-806 Poznan, Poland.

Background: Acne vulgaris is one of the most common skin diseases. One of the therapeutic options recommended for severe acne or acne that has not responded to previous therapies is isotretinoin. However, its use may lead to adverse changes in the serum lipid profile and increased levels of transaminases. Read More

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Neue Fixkombination zur Behandlung von Akne.

MMW Fortschr Med 2022 04;164(7):66

Springer Medizin, München, Germany.

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Non-conventional therapeutical approaches to acne vulgaris related to its association with metabolic disorders.

Eur J Pharmacol 2022 May 1;923:174936. Epub 2022 Apr 1.

Department of Psycho-neurosciences and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073, Oradea, Romania. Electronic address:

The ever-increasing frequency of metabolic syndrome (MetS) is still a major challenge of the public health care system, worldwide. In recent years, researchers have been drawn to the uncommon (at first look) link between skin illnesses and MetS. Because of the pro-inflammatory mechanisms and insulin resistance (IR) that are upregulated in metabolic syndrome, many skin disorders are correlated to metabolic dysfunctions, including acne vulgaris. Read More

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Going global with assessing the acne burden: is the evidence worth the effort?

Luigi Naldi

Br J Dermatol 2022 04;186(4):605

Centro Studi GISED, Bergamo, and Department of Dermatology, AULSS8, San Bortolo General Hospital, Vicenza, Italy.

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qPCR-Based Antibiotics Resistance Assay (ACQUIRE) Reveals Widespread Macrolide Resistance in Acne Patients and Can Eliminate Macrolide Misuse in Acne Treatment.

Front Public Health 2022 18;10:787299. Epub 2022 Mar 18.

Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha, China.

Background: Macrolides have been widely used to treat moderate-to-severe acne for more than 50 years. However, the prevalent antibiotic resistance of Propionibacterium acnes, along with the absence of clinically available resistance tests, has made macrolide misuse a frequent occurrence around the globe, with serious consequences.

Objective: We developed (qPCR)-based antibiotics resistance assay (ACQUIRE) to enable fast and accurate detection of macrolide resistance in clinical settings, representing an opportunity to administer antibiotics more wisely and improve the quality of care. Read More

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Hormonal Treatment of Acne and Hidradenitis Suppurativa in Adolescent Patients.

Dermatol Clin 2022 Apr 4;40(2):167-178. Epub 2022 Mar 4.

Penn State/ Hershey Medical Center, Department of Dermatology, 500 University Drive, Hershey, PA 17033, USA; Penn State/ Hershey Medical Center, Departments of Dermatology and Pediatrics, 500 University Drive, Hershey, PA 17033, USA. Electronic address:

Homeostasis of the cutaneous microenvironment is complex and depends on multiple intrinsic and extrinsic factors, including the influence of hormones. Hormones exert action on the hair follicle and associated sebaceous glands via both endocrine and intracrine mechanisms. The profound impact of hormonal action on follicular homeostasis can be leveraged in the treatment of disorders, such as acne and hidradenitis suppurativa. Read More

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Prevention and management of acneiform rash associated with EGFR inhibitor therapy: A systematic review and meta-analysis.

Asia Pac J Clin Oncol 2022 Mar 29. Epub 2022 Mar 29.

Australian National University Medical School, College of Health and Medicine, The Australian National University, Canberra, Australian Capital Territory, Australia.

Introduction: Epidermal growth factor receptor (EGFR) inhibitors are established therapies for advanced lung, colorectal, and head and neck cancers. They commonly cause acneiform eruptions that affect patient quality of life and may lead to discontinuation of therapy.

Methods: A systematic review and meta-analysis was undertaken to assess strategies for the prevention and reactive management of acneiform rash associated with EGFR inhibitor therapy for advanced lung, colorectal, and head and neck cancers. Read More

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Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting.

PLoS Pathog 2022 03 28;18(3):e1010420. Epub 2022 Mar 28.

Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders such as acne vulgaris. Read More

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MicroRNA Cross-Involvement in Acne Vulgaris and Hidradenitis Suppurativa: A Literature Review.

Int J Mol Sci 2022 Mar 17;23(6). Epub 2022 Mar 17.

Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Via Consolare Valeria-Gazzi, 98125 Messina, Italy.

Acne Vulgaris (AV) and Hidradenitis suppurativa (HS) are common chronic inflammatory skin conditions that affect the follicular units that often coexist or are involved in differential diagnoses. Inflammation in both these diseases may result from shared pathways, which may partially explain their frequent coexistence. MicroRNAs (miRNAs) are a class of endogenous, short, non-protein coding, gene-silencing or promoting RNAs that may promote various inflammatory diseases. Read More

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Bee Venom and Its Major Component Melittin Attenuated - and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway.

Int J Mol Sci 2022 Mar 15;23(6). Epub 2022 Mar 15.

Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.

Acne vulgaris is the most common disease of the pilosebaceous unit. The pathogenesis of this disease is complex, involving increased sebum production and perifollicular inflammation. Understanding the factors that regulate sebum production is important in identifying novel therapeutic targets for the treatment of acne. Read More

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