11,737 results match your criteria Acneiform Eruptions


Cutaneous toxicities of antineoplastic agents: data from a large cohort of Greek patients.

Support Care Cancer 2019 Mar 27. Epub 2019 Mar 27.

Dermato-Oncology Department, Cutaneous Toxicities Clinic, Andreas Sygros Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Purpose: Cutaneous toxicities from novel anticancer treatments are an emerging problem in dermato-oncology. However, the prevalence of those toxicities and necessity of skin consultations are currently unknown. The purpose of our study was to perform an epidemiologic analysis of cutaneous toxicities that were referred to our cutaneous toxicity clinic in Athens, Greece. Read More

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http://link.springer.com/10.1007/s00520-019-04751-y
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http://dx.doi.org/10.1007/s00520-019-04751-yDOI Listing
March 2019
3 Reads

Pulsed-dye laser as an adjuvant treatment for papulopustular eruptions from epidermal growth factor receptor inhibitors, a randomized blinded split-faced controlled trial.

Lasers Surg Med 2019 Mar 7. Epub 2019 Mar 7.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Skin and Allergy Research Unit, Chulalongkorn University, Bangkok, Thailand.

Objectives: To investigate the efficacy of pulsed-dye laser (PDL) as an adjunctive treatment for facial papulopustular eruptions from EGFR inhibitors (EGFRi).

Methods: Fourteen patients with facial acneiform eruptions were recruited. Half side of the face was randomized to receive PDL treatment while the other side served as a control. Read More

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http://dx.doi.org/10.1002/lsm.23080DOI Listing
March 2019
2 Reads

Cutaneous reactions to targeted therapies in children with CNS tumors: A cross-sectional study.

Pediatr Blood Cancer 2019 Jun 28;66(6):e27682. Epub 2019 Feb 28.

Dermatology Program, Boston Children's Hospital, Boston, Massachusetts.

Background: MAPK (RAS-RAF-MEK-ERK-MAP) and mTOR inhibitors are novel treatments for pediatric central nervous system (CNS) tumors. The literature on common cutaneous adverse reactions to these therapies is sparse in the pediatric population. The aim of this study was to describe common cutaneous adverse reactions to BRAF, MEK, and mTOR inhibitors in children with CNS tumors. Read More

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http://dx.doi.org/10.1002/pbc.27682DOI Listing
June 2019
1 Read

Adult female acne: a guide to clinical practice.

An Bras Dermatol 2019 Jan-Feb;94(1):62-75

Service of Cosmiatry, Department of Dermatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo (SP), Brazil.

Background: Acne in women is often associated with anxiety and depression, and may persist from adolescence as well as manifest for the first time in adulthood. Genetic and hormonal factors contribute to its etiopathogenesis, and maintenance treatment is required, usually for years, due to its clinical evolution.

Objective: To develop a guide for the clinical practice of adult female acne. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20198203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360964PMC
February 2019

Eosinophilic pneumonia: remember topical drugs as a potential etiology.

J Bras Pneumol 2018 Nov-Dec;44(6):522-524

. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.

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http://dx.doi.org/10.1590/S1806-37562018000000028DOI Listing
March 2019
1 Read

Novel Tretinoin 0.05% Lotion for Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris in a Hispanic Population

J Drugs Dermatol 2019 01;18(1):32-38

Background: Acne vulgaris (acne) is the most common dermatologic disease seen in a racially, geographically, politically, culturally, and socioeconomically diverse Hispanic population. Despite their growing demographics in the US, there are few studies evaluating acne treatment in this population. Potential for skin irritation and dryness, as well as pigmentary changes are key concerns. Read More

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January 2019
14 Reads

Reaccion acneiforme noduloquistica secundaria a vemurafenib con buena respuesta a isotretinoina oralSevere acneiform eruption associated with vemurafenib with response to isotretinoin.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Department of Dermatology, Hospital Universitario Fundacion Alcorcon, Madrid.

Vemurafenib, a kinase inhibitor that targets tumors with the BRAF V600E mutation, is a promising option for unresectable or metastatic melanoma. Cutaneous side-effects have been reported including alopecia, photosensitivity, squamous cell carcinoma, keratoacanthomas, keratosis pilaris-like eruption, and palmoplantar hyperkeratosis. Acneiform eruptions have been reported in 3%-6% of the patients treated with BRAF inhibitors,and 5 cases are described in the literature. Read More

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August 2018
3 Reads

Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris in a preadolescent population.

Pediatr Dermatol 2019 Mar 18;36(2):193-199. Epub 2019 Jan 18.

Dow Pharmaceutical Sciences Inc., Petaluma, California.

Background: Acne vulgaris (acne) is a common skin condition in children and adolescents. Efficacy of tretinoin is well documented in studies that included pediatric patients (12-18 years of age). With acne routinely presenting in younger patients, data are needed in this important group. Read More

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http://dx.doi.org/10.1111/pde.13744DOI Listing
March 2019
3 Reads

The microbiome in preadolescent acne: Assessment and prospective analysis of the influence of benzoyl peroxide.

Pediatr Dermatol 2019 Mar 18;36(2):200-206. Epub 2019 Jan 18.

Department of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, California.

Background/objectives: The pathogenesis of preadolescent acne has not been well studied, and it is uncertain if Cutibacterium acnes is a predominant organism in the microbiome in this age group. The aim of this study was to analyze the microbiome of preadolescent females and to assess whether benzoyl peroxide impacts the microbiome.

Methods: The study enrolled girls, aged 7-12 years, with evidence of at least six acne lesions who had not been previously treated. Read More

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http://dx.doi.org/10.1111/pde.13741DOI Listing
March 2019
2 Reads

[Advancement in phodynamic therapy for non-neoplastic skin diseases].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Dec;43(12):1380-1383

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Photodynamic therapy is mainly used in dermatology to treat skin tumors, precancerous lesions, and condyloma acuminatum. Due to its excellent tissue selectivity, easy operation and good cosmetic effect, it has been gradually applied to the treatment of various non-neoplastic skin diseases, such as verruca acuminata, acne, rosacea, chronic skin ulcer, fungal diseases, keloid, and so on. Here is the review on the advancement in photodynamic therapy for non-neoplastic skin diseases. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.12.016DOI Listing
December 2018
2 Reads

Hop Extract Acts as an Antioxidant with Antimicrobial Effects against and .

Molecules 2019 Jan 9;24(2). Epub 2019 Jan 9.

Research Centre skinitial, Department of Dermatology, University Medical Center, 79104 Freiburg, Germany.

Acne is associated with hyperkeratosis, elevated levels of skin sebum and growth of () and (). Furthermore, promotes inflammation by inducing IL-6 production and oxidative stress. The aim of this study was to assess the antioxidant, anti-inflammatory and antibacterial potential of a hop-CO₂-extract with 50% humulone and lupulone. Read More

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http://dx.doi.org/10.3390/molecules24020223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359372PMC
January 2019
1 Read

Clinical Characteristics of Japanese Patients with Palmoplantar Pustulosis.

Clin Drug Investig 2019 Mar;39(3):241-252

Department of Dermatology, Fukushima Medical University, Hikarigaoka 1, Fukushima, 960-1295, Japan.

Palmoplantar pustulosis (PPP) is a chronic inflammatory disorder characterized by sterile pustules predominantly involving the palms and soles. The purpose of this review was to describe the characteristics of Japanese PPP patients as PPP is frequently observed within the Japanese population. Most Japanese dermatologists consider PPP a distinct entity, and co-existence of PPP and psoriasis is rare; however, outside Japan, PPP is often considered to be palmoplantar psoriasis, and an extra-palmoplantar lesion associated with PPP is considered to be psoriasis. Read More

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http://link.springer.com/10.1007/s40261-018-00745-6
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http://dx.doi.org/10.1007/s40261-018-00745-6DOI Listing
March 2019
19 Reads

Acne Vulgaris.

Authors:
Fei Han

N Engl J Med 2019 01;380(2):199

Suqian First Hospital, Suqian, China

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http://dx.doi.org/10.1056/NEJMc1814789DOI Listing
January 2019

Acne Vulgaris.

N Engl J Med 2019 01;380(2):199-200

Penn State Hershey Medical Center, Hershey, PA

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http://dx.doi.org/10.1056/NEJMc1814789DOI Listing
January 2019

Recent advances in understanding ( ) in acne.

F1000Res 2018 19;7. Epub 2018 Dec 19.

Department of Dermatology, Andreas Syggros Hospital, University of Athens, Athens, Greece.

The skin commensal , recently renamed , along with the other major pathophysiological factors of increased seborrhea, hyperkeratinization of the pilosebaceous unit, and inflammation, has long been implicated in the pathogenesis of acne. Recent advances have contributed to our understanding of the role of in acne. Although there are no quantitative differences in of the skin of patients with acne compared with controls, the phylogenic groups display distinct genetic and phenotypic characteristics, biofilms are more frequent in acne, and different phylotypes may induce distinct immune responses in acne. Read More

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https://f1000research.com/articles/7-1953/v1
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http://dx.doi.org/10.12688/f1000research.15659.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305227PMC
March 2019
12 Reads

Retinoids in Acne Management: Review of Current Understanding, Future Considerations, and Focus on Topical Treatments

Authors:
Anna Chien

J Drugs Dermatol 2018 Dec;17(12):s51-55

Acne vulgaris is the most common skin condition affecting adolescents and young adults with a tremendous psychosocial impact. Its pathogenic hallmarks include follicular dyskeratosis, increased sebum production, and inflammation induced by Cutibacterium (formerly Propionibacterium) acnes within the follicle. Retinoids, derived from vitamin A, are the mainstays of acne treatment given they address the key pathogenic pathways of acne. Read More

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December 2018
5 Reads

Evaluation, Prevention, and Management of Acne Scars: Issues, Strategies, and Enhanced Outcomes

J Drugs Dermatol 2018 12;17(12):s44-48

Acne is a common disease affecting a high percentage of the younger population. Without appropriate and effective primary prevention of scarring, post-acne scars occur in about 80-95% of all patients. Acne scarring is the result of an alteration of the healing process and it can have deep psychosocial implications for patients. Read More

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December 2018
9 Reads

Acne and Scarring: Facing the Issue to Optimize Outcomes

Authors:
Jerry Tan

J Drugs Dermatol 2018 12;17(12):s43

This supplement summarize recent advances in the scientific understanding of acne pathogenesis as it relates to effective treatment acne in patients of all skin types and describes the role of retinoids in the management of acne and effective treatment and prevention strategies for hypertrophic and atrophic acne scarring in all skin types. Read More

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December 2018
6 Reads

Dermatology today and tomorrow: from symptom control to targeted therapy.

J Eur Acad Dermatol Venereol 2019 Jan;33 Suppl 1:3-36

Department of Dermatology, Clinical Research and Development Center, Pierre Fabre Dermo-Cosmétique, Toulouse University Hospital, Toulouse, France.

For many decades and until recently, medical approach to dermatologic diseases has been based on the physician's ability to recognize and treat symptoms. Nowadays, advances in the understanding of the biology of diseases and in technologies for intervening against them have allowed physicians to diagnose and treat underlying disease processes rather than simply addressing the symptoms. This means that rather than addressing 'the disease in humans', physicians can now address the particular pathologic (biologic, molecular) disturbance as it presents in the individual patient, i. Read More

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http://doi.wiley.com/10.1111/jdv.15335
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http://dx.doi.org/10.1111/jdv.15335DOI Listing
January 2019
11 Reads

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.

Nat Commun 2018 12 12;9(1):5075. Epub 2018 Dec 12.

Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London, London, SE1 9RT, UK.

Acne vulgaris is a highly heritable common, chronic inflammatory disease of the skin for which five genetic risk loci have so far been identified. Here, we perform a genome-wide association study of 3823 cases and 16,144 controls followed by meta-analysis with summary statistics from a previous study, with a total sample size of 26,722. We identify 20 independent association signals at 15 risk loci, 12 of which have not been previously implicated in the disease. Read More

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http://dx.doi.org/10.1038/s41467-018-07459-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290788PMC
December 2018
5 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 11;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
15 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 11;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
17 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 11;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
17 Reads

Integrated Cooling-Vacuum-Assisted Non-Fractional 1540-nm Erbium:Glass Laser: A New Modality for the Simultaneous Effective Treatment of Acne Lesions and Scars

J Drugs Dermatol 2018 11;17(11):1173 - 1176

Introduction: Acne vulgaris is a common skin disorder with a significant impact on patients' quality of life. There is currently no treatment designated to treat acne lesions and scars concurrently. However, mid-infrared lasers may promote neocollagenesis within atrophic scars, while exerting a beneficial effect on acne lesions. Read More

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November 2018
6 Reads

Managing polycystic ovary syndrome in primary care.

Singapore Med J 2018 Nov;59(11):567-571

Department of Endocrinology, Changi General Hospital, Singapore.

Polycystic ovary syndrome (PCOS) presents with a spectrum of conditions resulting from androgen excess, anovulation and metabolic syndrome. Patients with PCOS may see their primary care physicians for various presentations, including hirsutism, acne, menstrual irregularities, infertility, obesity, and psychiatric disorders such as anxiety and depression. Management of these patients should include screening for Type 2 diabetes mellitus, dyslipidaemia and hypertension. Read More

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http://dx.doi.org/10.11622/smedj.2018135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250763PMC
November 2018
5 Reads

New Concepts, Concerns, and Creations in Acne.

Dermatol Clin 2019 Jan 1;37(1):1-9. Epub 2018 Nov 1.

The Acne Treatment and Research Center of the DermGroup, 310 Madison Avenue, Morristown, NJ 07960, USA; Rutgers Robert Wood Johnson Medical Center, Piscataway, NJ 08820, USA. Electronic address:

Laboratory monitoring for patients on isotretinoin should include creatinine kinase in athletic males and the more liver-specific gamma glutamyltransferase. There is mounting evidence that acne pathophysiology includes a barrier defect and subsequent microbiome disruption. Avoidance of acne scars with early and aggressive treatment is a more efficient and cost-effective option than subsequent treatment. Read More

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http://dx.doi.org/10.1016/j.det.2018.07.002DOI Listing
January 2019
49 Reads

Transconjugation of erm(X) conferring high-level resistance of clindamycin for Cutibacterium acnes.

J Med Microbiol 2019 Jan 15;68(1):26-30. Epub 2018 Nov 15.

1​Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.

Cutibacterium acnes (C. acnes) can become an exacerbating factor in acne vulgaris. Clindamycin has been most frequently used for the treatment of inflammatory acne vulgaris. Read More

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http://dx.doi.org/10.1099/jmm.0.000875DOI Listing
January 2019
1 Read

Novel nicotinamide skin-adhesive hot melt extrudates for treatment of acne.

Expert Opin Drug Deliv 2018 12 15;15(12):1165-1173. Epub 2018 Nov 15.

a Centre for Pharmaceutical Engineering Science , University of Bradford , Bradford , UK.

Objectives: Hot melt extrusion is a continuous process with wide industrial applicability. Till current date, there have been no reports on the formulation of extrudates for topical treatment of dermatological diseases.

Methods: The aim of the present work was to prepare and characterize medicated hot melt extrudates based on Soluplus polymer and nicotinamide, and to explore their applicability in acne treatment. Read More

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http://dx.doi.org/10.1080/17425247.2018.1546287DOI Listing
December 2018
4 Reads

Is acne in adolescence associated with prostate cancer risk? Evidence from a meta-analysis.

PLoS One 2018 7;13(11):e0206249. Epub 2018 Nov 7.

Department of Geriatrics, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Introduction: Previous studies regarding the relationship between acne and prostate cancer risk have reported inconsistent results. We performed the present meta-analysis of observational studies to summarize the evidence on this association.

Methods: A comprehensive literature search up to March 2018 was performed in PubMed, Scopus, Web of Science, and Chinese National Knowledge Infrastructure (CNKI) databases. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206249PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221330PMC
April 2019
13 Reads

The effect of continuous high versus low dose oral isotretinoin regimens on dermcidin expression in patients with moderate to severe acne vulgaris.

Dermatol Ther 2018 11 5;31(6):e12715. Epub 2018 Nov 5.

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

The continuous low dose (LD) isotretinoin is frequently used in the treatment regimen for acne vulgaris. However, data about its antimicrobial are lacking. The present study aimed to investigate dermcidin expression and the effects of low and conventional dose isotretinoin on its expression in acne vulgaris patients. Read More

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http://dx.doi.org/10.1111/dth.12715DOI Listing
November 2018
1 Read

Social Appearance Anxiety in Adult Patients with Acne: A Cross-Sectional Study.

Acta Dermatovenerol Croat 2018 Oct;26(3):220-225

Fatma Sule Afsar, MD 2040/4 Sok. No:5 (Flamingo 20) D:65 35540 Mavisehir, Izmir, Turkey;

The severity of acne may not directly reflect the psychological state of a patient. The aim of the present study was to evaluate the social appearance anxiety with overall morbidity in patients with acne. One hundred adult patients with acne and 67 age and sex-matched healthy controls were enrolled in the study. Read More

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October 2018
2 Reads

Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.

Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39

Institut Universitaire du Cancer Toulouse - Oncopole, 1 avenue Irène Joliot-Curie, 31059, TOULOUSE Cedex 9, France.

Targeted therapies and immunotherapies are associated with a wide range of dermatologic adverse events (dAEs) resulting from common signaling pathways involved in malignant behavior and normal homeostatic functions of the epidermis and dermis. Dermatologic toxicities include damage to the skin, oral mucosa, hair, and nails. Acneiform rash is the most common dAE, observed in 25-85% of patients treated by epidermal growth factor receptor and mitogen-activated protein kinase kinase inhibitors. Read More

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http://link.springer.com/10.1007/s40257-018-0384-3
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http://dx.doi.org/10.1007/s40257-018-0384-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244569PMC
November 2018
16 Reads

Treatment of Moderate Acne Vulgaris in Fitzpatrick Skin Type V or VI: Efficacy and Tolerability of Fixed Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.75% Gel.

J Drugs Dermatol 2018 Oct;17(10):1107-1112

Background: Acne vulgaris (acne) is the most common skin disease in patients who have darker skin with most frequent sequelae of post inflammatory hyperpigmentation (PIH).

Methods: Open label study in 20 patients (mean age 32 years) with Fitzpatrick Skin Type V or VI and with moderate facial acne treated with clindamycin phosphate 1.2%/benzoyl peroxide 3. Read More

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October 2018
14 Reads

Novel Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris: Assessment of Efficacy and Safety in Patients Aged 9 Years and Older.

J Drugs Dermatol 2018 Oct;17(10):1084-1091

Background: Topical tretinoin has been extensively studied in clinical trials, and its essential role in the treatment of acne vulgaris (acne) established through evidence-based guidelines.

Objective: To evaluate efficacy, safety, and tolerability of a novel tretinoin 0.05% lotion in moderate-to-severe acne in patients aged 9 years and older. Read More

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October 2018
11 Reads

Effectiveness and Safety of Acne Scar Treatment With Nonanimal Stabilized Hyaluronic Acid Gel.

Dermatol Surg 2018 11;44 Suppl 1:S10-S18

Galderma Aesthetics, Uppsala, Sweden.

Background: Acne scarring affects most patients with acne and have a negative impact on quality of life. New effective treatment options offering minimal downtime are therefore needed.

Objective: To evaluate improvement in overall facial appearance after hyaluronic acid (HA) treatment of atrophic acne scars. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001689DOI Listing
November 2018
18 Reads

СLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH ADOLESCENCE ACNE AND ACNE TARDA.

Georgian Med News 2018 Sep(282):103-106

JSC "Astana Medical University", Kazakhstan.

Acne is a chronic recurrent androgen-mediated disease of the pilosebaceous complex with a multifactorial genetically determined development mechanism. Currently, there is a tendency to persistent course of the disease, resistance to therapy forms of acne, late debut and change the clinical picture of acne. This could be due to various factors, such as polycystic ovary syndrome, microadenoma and pituitary adenoma, congenital adrenal hyperplasia, SAHA syndrome, etc. Read More

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September 2018
4 Reads

Highly efficient and biocompatible nanoparticle-based photosensitizer for treatment of acne vulgaris.

Nanomedicine (Lond) 2018 10 19;13(20):2629-2636. Epub 2018 Oct 19.

Department of Chemistry, University of Cincinnati, Cincinnati 45221, OH, USA.

Aim: Nanoparticle-based photosensitizers containing silver core and mesoporous silica shell with hematoporphyrin IX embedded were developed to treat vulgaris photodynamically.

Materials & Methods: The hybrid photosensitizers were dispersed in 30% polyethylene glycol (PEG-200) solution and used for the photodynamic treatment of Staphylococcus epidermidis and Propionibacterium acnes under the illumination of a portable LED (∼410 nm).

Results: After a 5 min illumination by the LED, the hybrid photosensitizers of 50 μg/ml displayed killing efficacy of approximately 5-log for S. Read More

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https://www.futuremedicine.com/doi/10.2217/nnm-2018-0125
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http://dx.doi.org/10.2217/nnm-2018-0125DOI Listing
October 2018
16 Reads

Plasma 25-Hydroxy Vitamin D is not Associated with Acne Vulgaris.

Nutrients 2018 Oct 17;10(10). Epub 2018 Oct 17.

Department Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Box 24923, Safat 13110, Kuwait.

Few studies have investigated the association between Acne vulgaris (AV) and vitamin D level. In this study we aimed to investigate the association between 25-hydroxyvitamin D (25-OH-VitD) level and AV in a country with plenty of sunshine. A cross-sectional study was conducted on 714 adolescents who were randomly selected from public schools using multistage cluster random sampling with probability proportional to size. Read More

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http://www.mdpi.com/2072-6643/10/10/1525
Publisher Site
http://dx.doi.org/10.3390/nu10101525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212990PMC
October 2018
16 Reads
3.148 Impact Factor

Prescribing isotretinoin for transgender youth: A pledge for more inclusive care.

Pediatr Dermatol 2019 Jan 15;36(1):169-171. Epub 2018 Oct 15.

Department of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.

As the transgender community has become increasingly visible in public life, a greater awareness of this group's unique health needs and obstacles to optimal medical care has developed. Unfortunately, transgender youth face multiple barriers within the health care system, including access to equitable and gender-affirming care. As dermatologists who care for children and adolescents, we must be aware of the challenges facing transgender youth and work to correct the disparities that exist for this vulnerable group. Read More

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http://dx.doi.org/10.1111/pde.13694DOI Listing
January 2019

Omentin Val/Val genotype increases predisposition to acne vulgaris without changing omentin serum level.

Cell Mol Biol (Noisy-le-grand) 2018 Sep 30;64(12):81-86. Epub 2018 Sep 30.

Department of Medical Biology and Genetics, Duzce University Institute of Health Science, Duzce, Turkey.

Acne vulgaris is the most frequent and multifactorial inflammatory skin disorder in all races. Obesity is considered to be a risk factor for acne due to its contribution to inflammation. The involvements of inflammatory (leptin and resistin) and anti-inflammatory (adiponectin) adipokines in the pathogenesis of acne were reported. Read More

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September 2018
4 Reads

Approaches to limit systemic antibiotic use in acne: Systemic alternatives, emerging topical therapies, dietary modification, and laser and light-based treatments.

J Am Acad Dermatol 2019 Feb 5;80(2):538-549. Epub 2018 Oct 5.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Acne is one of the most common diseases worldwide and affects ∼50 million individuals in the United States. Oral antibiotics are the most common systemic agent prescribed for the treatment of acne. However, their use might be associated with a variety of adverse outcomes including bacterial resistance and disruption of the microbiome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183267
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http://dx.doi.org/10.1016/j.jaad.2018.09.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333507PMC
February 2019
22 Reads

Demographic and clinical features of hidradenitis suppurativa in Korea.

J Dermatol 2018 Dec 8;45(12):1389-1395. Epub 2018 Oct 8.

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS in Korea. Read More

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http://dx.doi.org/10.1111/1346-8138.14656DOI Listing
December 2018
8 Reads

Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris.

Microbiome 2018 10 2;6(1):177. Epub 2018 Oct 2.

Department of Dermatology, University of California San Diego, La Jolla, CA, 92037, USA.

Acne is one of the most common skin diseases worldwide and results in major health care costs and significant morbidity to severely affected individuals. However, the pathophysiology of this disorder is not well understood. Host-microbiome interactions that affect both innate and adaptive immune homeostasis appear to be a central factor in this disease, with recent observations suggesting that the composition and activities of the microbiota in acne is perturbed. Read More

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http://dx.doi.org/10.1186/s40168-018-0558-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169095PMC
October 2018
5 Reads

Acne Vulgaris.

N Engl J Med 2018 Oct;379(14):1343-1352

From the Departments of Dermatology and Pediatrics, Penn State Hershey Medical Center, Pennsylvania State University College of Medicine, Hershey.

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http://dx.doi.org/10.1056/NEJMcp1702493DOI Listing
October 2018
10 Reads

Daily Intake of Soft Drinks and Moderate-to-Severe Acne Vulgaris in Chinese Adolescents.

J Pediatr 2019 01 28;204:256-262.e3. Epub 2018 Sep 28.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; Hunan Key Laboratory of Skin Cancer and Psoriasis, Changsha, China; Hunan Engineering Center of Skin Health and Disease, Changsha, China. Electronic address:

Objectives: To investigate the association of soft drink consumption and the intake of sugar from soft drinks with the prevalence of acne in adolescents.

Study Design: This was a university-based epidemiologic investigation that included 8226 students who underwent health examinations and a questionnaire survey inquiring about the intake of soft drinks. Skin diseases were diagnosed by certificated dermatologists during the health examination. Read More

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http://dx.doi.org/10.1016/j.jpeds.2018.08.034DOI Listing
January 2019
15 Reads
3.790 Impact Factor

Low-dose blue light irradiation enhances the antimicrobial activities of curcumin against Propionibacterium acnes.

J Photochem Photobiol B 2018 Dec 26;189:21-28. Epub 2018 Sep 26.

Department of Laboratory Medicine and Biotechnology, Tzu-Chi University, Hualien 970, Taiwan. Electronic address:

Propionibacterium acnes (P. acnes) is an opportunistic infection in human skin that causes acne vulgaris. Antibiotic agents provide the effective eradication of microbes until the development of drug-resistant microbes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10111344183015
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http://dx.doi.org/10.1016/j.jphotobiol.2018.09.021DOI Listing
December 2018
6 Reads

Stigma predicts health-related quality of life impairment, psychological distress, and somatic symptoms in acne sufferers.

PLoS One 2018 28;13(9):e0205009. Epub 2018 Sep 28.

Department of Psychology and Centre for Social Issues Research, Faculty of Education and Health Sciences, University of Limerick, Limerick, Republic of Ireland.

Acne vulgaris has been associated with deficits in psychological well-being and health-related quality of life. Few studies have investigated how stigma contributes to our understanding of the well-being of acne sufferers, although it is clear that acne is stigmatized and stigmatization is associated with impaired well-being. The current study aimed to investigate the ability of perceived stigma to predict health-related quality of life, psychological distress, and somatic symptoms over and above established predictors. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205009PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161901PMC
March 2019
8 Reads

Development of Patient Decision Aids for Plaque Psoriasis and Acne.

Dermatol Online J 2018 Jul 15;24(7). Epub 2018 Jul 15.

Windsor Clinical Research Inc. Windsor.

Introduction: Despite proven benefits in other medical specialties, there is a paucity of patient decision aids (PDAs) in dermatology. The present study developed online PDAs for acne and psoriasis, incorporating iterative patient and physician feedback, in accordance with International Patient Decision Aid Standards (IPDAS).

Design And Method: Content was adapted from clinical practice guidelines and primary research and formatted for an 8th grade reading level. Read More

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July 2018
13 Reads

The therapeutic effect of tanshinone IIA on Propionibacterium acnes-induced inflammation in vitro.

Authors:
Yifan Li Yali Zhou

Dermatol Ther 2018 11 24;31(6):e12716. Epub 2018 Sep 24.

Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, China.

Acne vulgaris, a chronic inflammatory skin disease, affects many adolescents. New therapeutic agents for acne allow for a higher therapeutic activity, but fewer side effects. Tanshinone IIA, a natural product, has been proved to exhibit antibacterial and anti-inflammatory abilities in many diseases. Read More

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http://dx.doi.org/10.1111/dth.12716DOI Listing
November 2018
2 Reads

A provider global assessment quality measure for clinical practice for inflammatory skin disorders.

J Am Acad Dermatol 2019 03 20;80(3):823-828. Epub 2018 Sep 20.

Department of Dermatology, University of Iowa, Iowa City, Iowa.

In our evolving health care system, dermatologists are increasingly being asked to prove the value of care they provide to patients with severe skin diseases. Current quality measures for inflammatory dermatoses have limited validity and feasibility. Through collaboration and a modified Delphi process, International Dermatology Outcome Measures and the American Academy of Dermatology sought to reach consensus on a valid and feasible provider-assessed global disease severity metric to be incorporated into a quality measure for inflammatory dermatoses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183259
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http://dx.doi.org/10.1016/j.jaad.2018.09.017DOI Listing
March 2019
13 Reads
4.450 Impact Factor