11,677 results match your criteria Acneiform Eruptions


Novel Tretinoin 0.05% Lotion for Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris in a Hispanic Population

J Drugs Dermatol 2019 Jan;18(1):32-38

Background: Acne vulgaris (acne) is the most common dermatologic disease seen in a racially, geographically, politically, culturally, and socioeconomically diverse Hispanic population. Despite their growing demographics in the US, there are few studies evaluating acne treatment in this population. Potential for skin irritation and dryness, as well as pigmentary changes are key concerns. Read More

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January 2019

Reaccion acneiforme noduloquistica secundaria a vemurafenib con buena respuesta a isotretinoina oralSevere acneiform eruption associated with vemurafenib with response to isotretinoin.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Department of Dermatology, Hospital Universitario Fundacion Alcorcon, Madrid.

Vemurafenib, a kinase inhibitor that targets tumors with the BRAF V600E mutation, is a promising option for unresectable or metastatic melanoma. Cutaneous side-effects have been reported including alopecia, photosensitivity, squamous cell carcinoma, keratoacanthomas, keratosis pilaris-like eruption, and palmoplantar hyperkeratosis. Acneiform eruptions have been reported in 3%-6% of the patients treated with BRAF inhibitors,and 5 cases are described in the literature. Read More

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August 2018
2 Reads

[Advancement in phodynamic therapy for non-neoplastic skin diseases].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Dec;43(12):1380-1383

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Photodynamic therapy is mainly used in dermatology to treat skin tumors, precancerous lesions, and condyloma acuminatum. Due to its excellent tissue selectivity, easy operation and good cosmetic effect, it has been gradually applied to the treatment of various non-neoplastic skin diseases, such as verruca acuminata, acne, rosacea, chronic skin ulcer, fungal diseases, keloid, and so on. Here is the review on the advancement in photodynamic therapy for non-neoplastic skin diseases. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.12.016DOI Listing
December 2018
1 Read

Acne Vulgaris.

Authors:
Fei Han

N Engl J Med 2019 01;380(2):199

Suqian First Hospital, Suqian, China

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http://dx.doi.org/10.1056/NEJMc1814789DOI Listing
January 2019

Acne Vulgaris.

N Engl J Med 2019 01;380(2):199-200

Penn State Hershey Medical Center, Hershey, PA

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http://dx.doi.org/10.1056/NEJMc1814789DOI Listing
January 2019

Retinoids in Acne Management: Review of Current Understanding, Future Considerations, and Focus on Topical Treatments

Authors:
Anna Chien

J Drugs Dermatol 2018 Dec;17(12):s51-55

Acne vulgaris is the most common skin condition affecting adolescents and young adults with a tremendous psychosocial impact. Its pathogenic hallmarks include follicular dyskeratosis, increased sebum production, and inflammation induced by Cutibacterium (formerly Propionibacterium) acnes within the follicle. Retinoids, derived from vitamin A, are the mainstays of acne treatment given they address the key pathogenic pathways of acne. Read More

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December 2018
3 Reads

Evaluation, Prevention, and Management of Acne Scars: Issues, Strategies, and Enhanced Outcomes

J Drugs Dermatol 2018 Dec;17(12):s44-48

Acne is a common disease affecting a high percentage of the younger population. Without appropriate and effective primary prevention of scarring, post-acne scars occur in about 80-95% of all patients. Acne scarring is the result of an alteration of the healing process and it can have deep psychosocial implications for patients. Read More

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December 2018
5 Reads

Acne and Scarring: Facing the Issue to Optimize Outcomes

Authors:
Jerry Tan

J Drugs Dermatol 2018 Dec;17(12):s43

This supplement summarize recent advances in the scientific understanding of acne pathogenesis as it relates to effective treatment acne in patients of all skin types and describes the role of retinoids in the management of acne and effective treatment and prevention strategies for hypertrophic and atrophic acne scarring in all skin types. Read More

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December 2018
4 Reads

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.

Nat Commun 2018 12 12;9(1):5075. Epub 2018 Dec 12.

Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London, London, SE1 9RT, UK.

Acne vulgaris is a highly heritable common, chronic inflammatory disease of the skin for which five genetic risk loci have so far been identified. Here, we perform a genome-wide association study of 3823 cases and 16,144 controls followed by meta-analysis with summary statistics from a previous study, with a total sample size of 26,722. We identify 20 independent association signals at 15 risk loci, 12 of which have not been previously implicated in the disease. Read More

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http://dx.doi.org/10.1038/s41467-018-07459-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290788PMC
December 2018
2 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 Nov;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
10 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 Nov;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
12 Reads

Once-Daily Topical Dapsone Gel, 7.5%: Effective for Acne Vulgaris Regardless of Baseline Lesion Count, With Superior Efficacy in Females

J Drugs Dermatol 2018 Nov;17(11):1192-1198

Introduction: Acne vulgaris is more common in females than males and is challenging to treat. A post hoc analysis of 2 clinical trials evaluated the effect of dapsone gel, 7.5% based on sex and baseline acne lesion count. Read More

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November 2018
9 Reads

Integrated Cooling-Vacuum-Assisted Non-Fractional 1540-nm Erbium:Glass Laser: A New Modality for the Simultaneous Effective Treatment of Acne Lesions and Scars

J Drugs Dermatol 2018 11;17(11):1173 - 1176

Introduction: Acne vulgaris is a common skin disorder with a significant impact on patients' quality of life. There is currently no treatment designated to treat acne lesions and scars concurrently. However, mid-infrared lasers may promote neocollagenesis within atrophic scars, while exerting a beneficial effect on acne lesions. Read More

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November 2018
4 Reads

Managing polycystic ovary syndrome in primary care.

Singapore Med J 2018 Nov;59(11):567-571

Department of Endocrinology, Changi General Hospital, Singapore.

Polycystic ovary syndrome (PCOS) presents with a spectrum of conditions resulting from androgen excess, anovulation and metabolic syndrome. Patients with PCOS may see their primary care physicians for various presentations, including hirsutism, acne, menstrual irregularities, infertility, obesity, and psychiatric disorders such as anxiety and depression. Management of these patients should include screening for Type 2 diabetes mellitus, dyslipidaemia and hypertension. Read More

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http://dx.doi.org/10.11622/smedj.2018135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250763PMC
November 2018
3 Reads

Transconjugation of erm(X) conferring high-level resistance of clindamycin for Cutibacterium acnes.

J Med Microbiol 2019 Jan 15;68(1):26-30. Epub 2018 Nov 15.

1​Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.

Cutibacterium acnes (C. acnes) can become an exacerbating factor in acne vulgaris. Clindamycin has been most frequently used for the treatment of inflammatory acne vulgaris. Read More

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http://dx.doi.org/10.1099/jmm.0.000875DOI Listing
January 2019

Treatment of Moderate Acne Vulgaris in Fitzpatrick Skin Type V or VI: Efficacy and Tolerability of Fixed Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.75% Gel.

J Drugs Dermatol 2018 Oct;17(10):1107-1112

Background: Acne vulgaris (acne) is the most common skin disease in patients who have darker skin with most frequent sequelae of post inflammatory hyperpigmentation (PIH).

Methods: Open label study in 20 patients (mean age 32 years) with Fitzpatrick Skin Type V or VI and with moderate facial acne treated with clindamycin phosphate 1.2%/benzoyl peroxide 3. Read More

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October 2018
11 Reads

Novel Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris: Assessment of Efficacy and Safety in Patients Aged 9 Years and Older.

J Drugs Dermatol 2018 Oct;17(10):1084-1091

Background: Topical tretinoin has been extensively studied in clinical trials, and its essential role in the treatment of acne vulgaris (acne) established through evidence-based guidelines.

Objective: To evaluate efficacy, safety, and tolerability of a novel tretinoin 0.05% lotion in moderate-to-severe acne in patients aged 9 years and older. Read More

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October 2018
8 Reads

Effectiveness and Safety of Acne Scar Treatment With Nonanimal Stabilized Hyaluronic Acid Gel.

Dermatol Surg 2018 11;44 Suppl 1:S10-S18

Galderma Aesthetics, Uppsala, Sweden.

Background: Acne scarring affects most patients with acne and have a negative impact on quality of life. New effective treatment options offering minimal downtime are therefore needed.

Objective: To evaluate improvement in overall facial appearance after hyaluronic acid (HA) treatment of atrophic acne scars. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001689DOI Listing
November 2018
10 Reads

СLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH ADOLESCENCE ACNE AND ACNE TARDA.

Georgian Med News 2018 Sep(282):103-106

JSC "Astana Medical University", Kazakhstan.

Acne is a chronic recurrent androgen-mediated disease of the pilosebaceous complex with a multifactorial genetically determined development mechanism. Currently, there is a tendency to persistent course of the disease, resistance to therapy forms of acne, late debut and change the clinical picture of acne. This could be due to various factors, such as polycystic ovary syndrome, microadenoma and pituitary adenoma, congenital adrenal hyperplasia, SAHA syndrome, etc. Read More

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September 2018
2 Reads

Highly efficient and biocompatible nanoparticle-based photosensitizer for treatment of acne vulgaris.

Nanomedicine (Lond) 2018 10 19;13(20):2629-2636. Epub 2018 Oct 19.

Department of Chemistry, University of Cincinnati, Cincinnati 45221, OH, USA.

Aim: Nanoparticle-based photosensitizers containing silver core and mesoporous silica shell with hematoporphyrin IX embedded were developed to treat vulgaris photodynamically.

Materials & Methods: The hybrid photosensitizers were dispersed in 30% polyethylene glycol (PEG-200) solution and used for the photodynamic treatment of Staphylococcus epidermidis and Propionibacterium acnes under the illumination of a portable LED (∼410 nm).

Results: After a 5 min illumination by the LED, the hybrid photosensitizers of 50 μg/ml displayed killing efficacy of approximately 5-log for S. Read More

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https://www.futuremedicine.com/doi/10.2217/nnm-2018-0125
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http://dx.doi.org/10.2217/nnm-2018-0125DOI Listing
October 2018
13 Reads

Plasma 25-Hydroxy Vitamin D is not Associated with Acne Vulgaris.

Nutrients 2018 Oct 17;10(10). Epub 2018 Oct 17.

Department Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Box 24923, Safat 13110, Kuwait.

Few studies have investigated the association between Acne vulgaris (AV) and vitamin D level. In this study we aimed to investigate the association between 25-hydroxyvitamin D (25-OH-VitD) level and AV in a country with plenty of sunshine. A cross-sectional study was conducted on 714 adolescents who were randomly selected from public schools using multistage cluster random sampling with probability proportional to size. Read More

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http://www.mdpi.com/2072-6643/10/10/1525
Publisher Site
http://dx.doi.org/10.3390/nu10101525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212990PMC
October 2018
10 Reads
3.148 Impact Factor

Prescribing isotretinoin for transgender youth: A pledge for more inclusive care.

Pediatr Dermatol 2019 Jan 15;36(1):169-171. Epub 2018 Oct 15.

Department of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.

As the transgender community has become increasingly visible in public life, a greater awareness of this group's unique health needs and obstacles to optimal medical care has developed. Unfortunately, transgender youth face multiple barriers within the health care system, including access to equitable and gender-affirming care. As dermatologists who care for children and adolescents, we must be aware of the challenges facing transgender youth and work to correct the disparities that exist for this vulnerable group. Read More

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http://dx.doi.org/10.1111/pde.13694DOI Listing
January 2019

Omentin Val/Val genotype increases predisposition to acne vulgaris without changing omentin serum level.

Cell Mol Biol (Noisy-le-grand) 2018 Sep 30;64(12):81-86. Epub 2018 Sep 30.

Department of Medical Biology and Genetics, Duzce University Institute of Health Science, Duzce, Turkey.

Acne vulgaris is the most frequent and multifactorial inflammatory skin disorder in all races. Obesity is considered to be a risk factor for acne due to its contribution to inflammation. The involvements of inflammatory (leptin and resistin) and anti-inflammatory (adiponectin) adipokines in the pathogenesis of acne were reported. Read More

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September 2018
4 Reads

Acne Vulgaris.

N Engl J Med 2018 Oct;379(14):1343-1352

From the Departments of Dermatology and Pediatrics, Penn State Hershey Medical Center, Pennsylvania State University College of Medicine, Hershey.

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http://dx.doi.org/10.1056/NEJMcp1702493DOI Listing
October 2018
10 Reads

Low-dose blue light irradiation enhances the antimicrobial activities of curcumin against Propionibacterium acnes.

J Photochem Photobiol B 2018 Dec 26;189:21-28. Epub 2018 Sep 26.

Department of Laboratory Medicine and Biotechnology, Tzu-Chi University, Hualien 970, Taiwan. Electronic address:

Propionibacterium acnes (P. acnes) is an opportunistic infection in human skin that causes acne vulgaris. Antibiotic agents provide the effective eradication of microbes until the development of drug-resistant microbes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10111344183015
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http://dx.doi.org/10.1016/j.jphotobiol.2018.09.021DOI Listing
December 2018
6 Reads

Development of Patient Decision Aids for Plaque Psoriasis and Acne.

Dermatol Online J 2018 Jul 15;24(7). Epub 2018 Jul 15.

Windsor Clinical Research Inc. Windsor.

Introduction: Despite proven benefits in other medical specialties, there is a paucity of patient decision aids (PDAs) in dermatology. The present study developed online PDAs for acne and psoriasis, incorporating iterative patient and physician feedback, in accordance with International Patient Decision Aid Standards (IPDAS).

Design And Method: Content was adapted from clinical practice guidelines and primary research and formatted for an 8th grade reading level. Read More

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July 2018
9 Reads

Serum irisin: A prognostic marker for severe acne vulgaris.

J Cosmet Dermatol 2018 Oct 20;17(5):931-934. Epub 2018 Sep 20.

Department of Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Benha, Egypt.

Background: Acne vulgaris is a common chronic inflammatory skin disease involving pilosebaceous units. Adipokines are secreted by adipose tissue and function as signaling networks communicating it with different organs. They may have role in pathogenesis of acne vulgaris and the associated insulin resistance. Read More

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http://dx.doi.org/10.1111/jocd.12753DOI Listing
October 2018
5 Reads

Artificial Intelligence for the Objective Evaluation of Acne Investigator Global Assessment.

J Drugs Dermatol 2018 Sep;17(9):1006-1009

Introduction: The evaluation of Acne using ordinal scales reflects the clinical perception of severity but has shown low reproducibility both intra- and inter-rater. In this study, we investigated if Artificial Intelligence trained on images of Acne patients could perform acne grading with high accuracy and reliabilities superior to those of expert physicians.

Methods: 479 patients with acne grading ranging from clear to severe and sampled from three ethnic groups participated in this study. Read More

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September 2018
13 Reads

Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials.

J Drugs Dermatol 2018 Sep;17(9):987-996

Background: Side effects may limit the use of current tetracycline-class antibiotics for acne.

Objective: Evaluate the efficacy and safety of once-daily sarecycline, a novel, narrow-spectrum tetracycline-class antibiotic, in moderate to severe acne.

Methods: Patients 9-45 years with moderate to severe facial acne (Investigator's Global Assessment [IGA] score ≥ 3, 20-50 inflammatory and ≤ 100 noninflammatory lesions, and ≤ 2 nodules) were randomized 1:1 to sarecycline 1. Read More

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September 2018
31 Reads

Acneiform eruptions: An unusual dermatological side effect of ribavirin.

Dermatol Ther 2018 09 19;31(5):e12679. Epub 2018 Sep 19.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/dth.12679DOI Listing
September 2018
2 Reads

Nanotechnological Carriers for Treatment of Acne.

Recent Pat Antiinfect Drug Discov 2018 ;13(2):105-126

I. K. Gujral Punjab Technical University, Jalandhar-Punjab 144601, India.

Background: Acne is a multifactorial skin disease associated with pilosebaceous unit and caused by bacteria Propionibacterium acnes and Acne vulgaris. Near about 95% people throughout the world suffer from acne at some point in their life span. This disease is more prominent in adults compared to neonates and prepubescent children. Read More

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http://dx.doi.org/10.2174/1574891X13666180918114349DOI Listing
January 2019
17 Reads

Mesothelial Stem Cells and Stromal Vascular Fraction: Use in Functional Disorders, Wound Healing, Fat Transfer, and Other Conditions.

Facial Plast Surg Clin North Am 2018 Nov 16;26(4):487-501. Epub 2018 Aug 16.

UCLA Department of Otolaryngology Head and Neck Surgery, Facial Plastic Surgery, 200 UCLA Medical Plaza, Suite 500, Los Angeles, CA 90095, USA.

Autologous human fat-derived mesenchymal stem cells are present in stromal vascular fraction. Stromal vascular fraction can be easily and safely extracted from lipoaspirate. The regenerative, antiinflammatory and immunomodulatory effects of stromal vascular fraction are being documented in ongoing therapeutic response studies. Read More

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http://dx.doi.org/10.1016/j.fsc.2018.06.009DOI Listing
November 2018
2 Reads

Is PASH Syndrome a Biofilm Disease?: A Case Series and Review of the Literature.

Wounds 2018 Aug;30(8):216-223

Barry University School of Podiatric Medicine, Miami Shores, FL.

Introduction: When occurring together, pyoderma gangrenosum, severe acne, and hidradenitis suppurativa have been described as PASH syndrome. Due to the chronic autoinflammatory state existing in affected patients, PASH syndrome has been attributed to the dysregulation of wound healing.

Case Reports: Two cases are presented that demonstrate the paradigmatic clinical features of PASH syndrome and its potential link as an expanding spectrum of bacterial biofilm disorder. Read More

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August 2018
33 Reads

Combination chemical peels are more effective than single chemical peel in treatment of mild-to-moderate acne vulgaris: A split face comparative clinical trial.

J Cosmet Dermatol 2018 Oct 10;17(5):802-810. Epub 2018 Sep 10.

Department of Dermatology and Venereology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Successful management of acne involves choosing proper medication. Chemical peeling is a well-known option in treatment of acne vulgaris.

Objective: To evaluate and compare the clinical efficacy and safety of combination chemical peels vs single peel in treatment of mild-to-moderate acne. Read More

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http://dx.doi.org/10.1111/jocd.12763DOI Listing
October 2018
2 Reads

Dermatoscopy and Reflectance Confocal Microscopy Correlations in Nonmelanocytic Disorders.

Dermatol Clin 2018 Oct 16;36(4):487-501. Epub 2018 Aug 16.

Dermatology Clinic, University of Catania, Via Santa Sofia 78, Catania 95123, Italy.

Dermatoscopy and in vivo reflectance confocal microscopy are noninvasive techniques that provide a horizontal approach, with an en face view of the skin structures. Both techniques assist in the clinical diagnosis of a variety of inflammatory and infectious cutaneous disorders. In many cases, they have shown concordance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183108
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http://dx.doi.org/10.1016/j.det.2018.05.015DOI Listing
October 2018
16 Reads

Tretinoin Loaded Nanoemulsion for Acne Vulgaris: Fabrication, Physicochemical and Clinical Efficacy Assessments.

Skin Pharmacol Physiol 2018 10;31(6):316-323. Epub 2018 Sep 10.

Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.

Background And Aim: Acne vulgaris is a common inflammatory skin condition which is treated using Tretinoin (TRE), a widely used retinoid. Nano emulations (NEs) are colloidal nano-sized particles that enhance the therapeutic efficacy of TRE and minimize adverse effects. This study is aimed at developing a TRE-loaded NE (NE-TRE) and at assessing the therapeutic effects of the formulation in acne vulgaris lesions, compared to conventional 0. Read More

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http://dx.doi.org/10.1159/000488993DOI Listing
November 2018
3 Reads
2.370 Impact Factor

Expression of inflammatory and fibrogenetic markers in acne hypertrophic scar formation: focusing on role of TGF-β and IGF-1R.

Arch Dermatol Res 2018 Oct 29;310(8):665-673. Epub 2018 Aug 29.

Department of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.

Acne vulgaris is a universal skin disease and it may leave a scar when the original skin lesion disappears. These scars can cause cosmetic problems and psychological burden, leading to poor quality of life of patients. Acne scars are classified into atrophic scars and hypertrophic scars. Read More

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http://link.springer.com/10.1007/s00403-018-1856-2
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http://dx.doi.org/10.1007/s00403-018-1856-2DOI Listing
October 2018
16 Reads

L. Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study.

Molecules 2018 Aug 28;23(9). Epub 2018 Aug 28.

Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

Antibiotics are often prescribed in acne treatment; however, and , the two of the major acne-associated bacteria, developed antibiotic resistance. Essential oils (EOs) present a natural, safe, efficacious and multifunctional alternative treatment. This study aimed to assess the potential anti-acne activity of selected seven EOs commonly used in Mediterranean folk medicine. Read More

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http://www.mdpi.com/1420-3049/23/9/2164
Publisher Site
http://dx.doi.org/10.3390/molecules23092164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225355PMC
August 2018
8 Reads

Effectiveness of photopneumatic technology: a descriptive review of the literature.

Lasers Med Sci 2018 Nov 24;33(8):1631-1637. Epub 2018 Aug 24.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., 2nd Floor, Unit 2099, Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.

Usage of photopneumatic technology has recently increased for treatment of different skin conditions such as acne, keratosis pilaris (KP), and rosacea. Photopneumatic devices combine gentle negative pressure with broad band pulsed light simultaneously to attack multiple targets in the skin for better treatment outcomes. In this literature review, we evaluate the efficacy of photopneumatic therapy on treatment of acne, keratosis pilaris (KP), and rosacea. Read More

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http://link.springer.com/10.1007/s10103-018-2619-1
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http://dx.doi.org/10.1007/s10103-018-2619-1DOI Listing
November 2018
21 Reads

Progestins and acne vulgaris: a review.

Dermatol Online J 2018 May 15;24(5). Epub 2018 May 15.

Department of Dermatology, University of California, Davis, Sacramento, California.

The role of exogenous progestin in the development of acne is unclear. Progestins are known for their androgenic potential, but newer generations of progestins have low or anti-androgenic activity. This review will evaluate the association between progestins found in hormonal long-acting reversible contraceptives (intrauterine devices and subdermal implants) and acne, as well as the role of oral contraceptives in acne management. Read More

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May 2018
4 Reads

Diet and dermatology: Google search results for acne, psoriasis, and eczema.

Cutis 2018 Jul;102(1):44;46;48

Goldenberg Dermatology, PC, New York, USA.

It is difficult to regulate the abundance of medical information that is available to patients on the Internet. This systematic review evaluated content available online related to diet and 3 dermatologic conditions: acne, psoriasis, and eczema. Ultimately, our results indicated that most of the information that can be found online regarding diet and these dermatologic conditions is unfounded and/or misleading. Read More

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July 2018
3 Reads

Acne treatment: analysis of acne-related social media posts and the impact on patient care.

Cutis 2018 Jul;102(1):41-43

Denver VA Medical Center, Colorado, and the College of Medicine, University of Colorado, Denver, USA.

Many patients use social media as a source of medical information on dermatologic diseases. Social media offers accessible methods of communicating with physicians, other patients, and pharmacies. The information gathered through social media posts has the potential to influence patients' views of their conditions and treatment options, though the source often is unknown. Read More

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July 2018
7 Reads

Update on acne scar treatment.

Cutis 2018 Jul;102(1):21;25;47;48

Goldenberg Dermatology, PC, New York, USA.

Acne vulgaris and postacne scarring are common in the general population. Even after lesions have resolved, scarring can lead to detrimental psychologic effects and can negatively impact patients' quality of life. Fortunately, there have been several recent advances in therapeutic options to treat acne scarring. Read More

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July 2018
14 Reads

Acne in Lomé, Togo: clinical aspects and quality of life of patients.

BMC Dermatol 2018 08 22;18(1). Epub 2018 Aug 22.

Dermatology Unit, Sylvanus Olympio Teaching Hospital, University of Lomé, B.P, 30785, Lomé, Togo.

Background: Acne is a chronic inflammatory condition affecting the pilosebaceous follicle that mainly affects adolescents and young adults. The aim of this study was to assess the quality of life (QOL) of patients with acne, and to determine the correlation between the QOL and the severity of acne, in Lomé (Togo).

Method: From July 2017 to February 2018, we conducted a study in three dermatology departments of Lomé. Read More

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https://bmcdermatol.biomedcentral.com/articles/10.1186/s1289
Publisher Site
http://dx.doi.org/10.1186/s12895-018-0075-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106930PMC
August 2018
8 Reads

pH and Acne.

Authors:
Nanna Schürer

Curr Probl Dermatol 2018 21;54:115-122. Epub 2018 Aug 21.

Acne is based on a complex, multifactorial pathophysiology beginning with a microcomedo. Comedogenesis involves follicular hyperproliferation and disturbed keratinization, hyperseborrhea and hyperplasia of sebaceous glands as well as disturbances in skin microbiome. Acne is treated with antibiotics, retinoids, keratolytics, hormonal and anti-inflammatory agents. Read More

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https://www.karger.com/Article/FullText/489525
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http://dx.doi.org/10.1159/000489525DOI Listing
December 2018
18 Reads

Gut microbiota alterations in moderate to severe acne vulgaris patients.

J Dermatol 2018 Oct 13;45(10):1166-1171. Epub 2018 Aug 13.

Department of Dermatology, Peking University Third Hospital, Beijing, China.

Acne vulgaris is a chronic inflammatory dermatosis affecting approximately 85% of adolescents. There are many factors contributing to the development of this ailment. A recent study indicated that gut microbiota takes part in the pathogenesis of acne. Read More

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http://doi.wiley.com/10.1111/1346-8138.14586
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http://dx.doi.org/10.1111/1346-8138.14586DOI Listing
October 2018
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Phase I dose-escalation trial of Sym004, an anti-EGFR antibody mixture, in Japanese patients with advanced solid tumors.

Cancer Sci 2018 Oct 25;109(10):3253-3262. Epub 2018 Sep 25.

National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

Sym004 is a 1:1 mixture of two antibodies targeting non-overlapping epitopes of the epidermal growth factor receptor that antagonizes ligand binding and induces receptor downregulation. In preclinical models, it has superior antitumor activity to cetuximab and panitumumab. Japanese adults aged ≥20 years with an Eastern Cooperative Oncology Group status of 0/1 and life expectancy ≥3 months were eligible. Read More

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http://dx.doi.org/10.1111/cas.13767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172077PMC
October 2018
7 Reads

Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults.

Nutrients 2018 Aug 9;10(8). Epub 2018 Aug 9.

Department of Production, Research, and Innovation, Region Zealand, 4180 Sorø, Denmark.

A meta-analysis can help inform the debate about the epidemiological evidence on dairy intake and development of acne. A systematic literature search of PubMed from inception to 11 December 2017 was performed to estimate the association of dairy intake and acne in children, adolescents, and young adults in observational studies. We estimated the pooled random effects odds ratio (OR) (95% CI), heterogeneity (²-statistics, -statistics), and publication bias. Read More

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http://dx.doi.org/10.3390/nu10081049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115795PMC
August 2018
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Lactase Persistence, Milk Intake, and Adult Acne: A Mendelian Randomization Study of 20,416 Danish Adults.

Nutrients 2018 Aug 8;10(8). Epub 2018 Aug 8.

Department of Production, Research, and Innovation, Region Zealand, 4180 Sorø, Denmark.

Whether there is a causal relationship between milk intake and acne is unknown. We tested the hypothesis that genetically determined milk intake is associated with acne in adults using a Mendelian randomization design. (rs4988235) is associated with lactase persistence () in Northern Europeans. Read More

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http://dx.doi.org/10.3390/nu10081041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115808PMC
August 2018
5 Reads

EGFR inhibitor-induced cut-like skin lesions of the fingers.

BMJ Case Rep 2018 Aug 1;2018. Epub 2018 Aug 1.

Lucy Curci Cancer Center, Eisenhower Health, Rancho Mirage, California, USA.

Cetuximab and osimertinib are epidermal growth factor receptors (EGFRs) inhibitors used in the treatment of several malignancies. These agents have been associated with several skin lesions, the most common being papulopustular acneiform rash involving the face, neck, chest and back. Herein, we describe a unique toxic effect of these agents involving the fingertips and lateral aspects of fingers in a small patient series. Read More

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http://dx.doi.org/10.1136/bcr-2017-224144DOI Listing
August 2018
16 Reads