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    The Effect of Skin Sebum, pH, and Moisture on Demodex Infestation in Acne Vulgaris and Rosacea Patients.
    Turkiye Parazitol Derg 2017 Sep;41(3):143-147
    Özel Melid Park Hastanesi, Malatya, Türkiye.
    Objective: Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. Read More

    Efficacy and tolerability of liposomal polyvinylpyrrolidone-iodine hydrogel for the localized treatment of chronic infective, inflammatory, dermatoses: an uncontrolled pilot study.
    Clin Cosmet Investig Dermatol 2017 22;10:373-384. Epub 2017 Sep 22.
    Mundipharma Research GmbH & Co.KG, Limburg (Lahn), Germany.
    Infection is common in many chronic, inflammatory skin conditions but is often difficult to treat, in part due to growing bacterial resistance to antibiotics. Liposomal polyvinyl-pyrrolidone (PVP)-iodine hydrogel has a unique mode of action, combining the antiseptic and anti-inflammatory actions of PVP-iodine with the drug delivery and moisturizing properties of liposomes. We investigated the utility of liposomal PVP-iodine to treat infective dermatoses. Read More

    Network pharmacology-based approach of novel traditional Chinese medicine formula for treatment of acute skin inflammation in silico.
    Comput Biol Chem 2017 Sep 14;71:70-81. Epub 2017 Sep 14.
    Department of Medical Research, China Medical University Hospital, Taichung 40447, Taiwan; Department of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou 510275, China. Electronic address:
    Matrix metalloproteinase-9 (MMP-9) appears to play an important role in acute skin inflammation. Subantimicrobial dose of tetracycline has been demonstrated to inhibit the activity of MMP-9 protein. However, long-term use tetracycline will induce side effect. Read More

    Treatment of Moderate-to-severe Acne Vulgaris in a Hispanic Population: A Post-hoc Analysis of the Efficacy and Tolerability of Clindamycin 1.2%/Benzoyl Peroxide 3.75% Gel.
    J Clin Aesthet Dermatol 2017 Jun 1;10(6):36-43. Epub 2017 Jun 1.
    Valeant Pharmaceuticals North America LLC, Bridgewater, New Jersey.
    Background: Acne vulgaris (acne) is highly prevalent in the Hispanic population as it is in other racial/ethnic groups. While nuances in the presentation, quality-of-life impact, and approach to therapy of acne have been reported in various racial ethnic groups and skin types, data on the Hispanic population are limited, and yet they are the fastest growing population in the United States. Potential for irritation, dryness, and pigmentary alteration (due to acne and/or treatment) are key concerns in the management of acne in Hispanic populations. Read More

    Living with Acne: Belief and Perception in a Sample of Indian Youths.
    Indian J Dermatol 2017 Sep-Oct;62(5):491-497
    Department of Dermatology, MMIMSR, Ambala, Haryana, India.
    Background: Acne vulgaris is a common disease among adolescent. There is paucity of information on knowledge and understanding of acne patients about their condition.

    Objective: This study was carried out to evaluate beliefs and perception of acne patient toward their understanding of disease, treatment option, and information source. Read More

    Psychosocial impact of acne and postinflammatory hyperpigmentation.
    An Bras Dermatol 2017 Jul-Aug;92(4):505-509
    Department of Psychiatry and Behavioral Sciences; University of Miami Miller School of Medicine - Miami (FL), USA.
    Background:: Acne is one of the most common skin diseases. It has significant effect on self-image and negative impact on quality of life. Postinflammatory hyperpigmentation is an acquired hypermelanosis that occurs after a skin injury or cutaneous inflammation. Read More

    Relationship between acne vulgaris and cosmetic usage in Sri Lankan urban adolescent females.
    J Cosmet Dermatol 2017 Sep 22. Epub 2017 Sep 22.
    Faculty of Medicine, Medical Education Development and Research Centre, University of Colombo, Colombo, Sri Lanka.
    Background: Acne vulgaris is one of the commonest skin disorders affecting up to 80% of the world population at least during adolescence. Significant psychosocial effects such as depression and poor personality development have been linked with acne, especially in female adolescents. Various causative factors, including cosmetic exposure, have been attributed toward acne. Read More

    Help-seeking behaviours, opportunistic treatment and psychological implications of adolescent acne: cross-sectional studies in schools and hospital outpatient departments in the UK.
    BMJ Open 2017 Sep 21;7(9):e016964. Epub 2017 Sep 21.
    Department of Adolescent Endocrinologist, University College London Hospitals NHS Foundation Trust, London, UK.
    Background: Acne vulgaris (acne) is a common adolescent skin condition. It is associated with negative psychological impacts and sufferers do not easily seek help, hence is undertreated.

    Objectives: We investigated the self-reported prevalence, severity and psychological sequelae of acne, together with assessing help-seeking behaviour and its barriers, in separate school and hospital samples. Read More

    Efficacy and Safety of Tazarotene 0.1% Plus Clindamycin 1% Gel Versus Adapalene 0.1% Plus Clindamycin 1% Gel in Facial Acne Vulgaris: A Randomized, Controlled Clinical Trial.
    Clin Drug Investig 2017 Sep 14. Epub 2017 Sep 14.
    Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
    Background: Acne vulgaris is a multifactorial disorder which is ideally treated with combination therapy with topical retinoids and antibiotics.

    Objectives: The present study was conducted to compare the efficacy and safety of tazarotene plus clindamycin against adapalene plus clindamycin in facial acne vulgaris.

    Methods: This study is a randomized, open-label, parallel design clinical trial conducted on 60 patients with facial acne at the outpatient dermatology department in a tertiary healthcare center. Read More

    Doxycycline-Induced Acute Pancreatitis: A Rare Adverse Event.
    Gastroenterology Res 2017 Aug 31;10(4):244-246. Epub 2017 Aug 31.
    Department of Pharmacology, St John's Medical College, Bangalore, India.
    Doxycycline is a broad-spectrum antibiotic belonging to the tetracycline group which acts by inhibiting bacterial protein synthesis. It is considered to be a relatively safe drug. We report a case of doxycycline-induced acute pancreatitis (DIAP) in an adult female patient who was started on the usual therapeutic dose 1 week before for acne vulgaris. Read More

    Chemical Peels: Indications and Special Considerations for the Male Patient.
    Dermatol Surg 2017 Sep 4. Epub 2017 Sep 4.
    *Division of Dermatology, Loyola University Medical Center, Maywood, Illinois; †Division of Dermatology & Dermatologic Surgery, Scripps Clinic, La Jolla, California.
    Background: Chemical peels are a mainstay of aesthetic medicine and an increasingly popular cosmetic procedure performed in men.

    Objective: To review the indications for chemical peels with an emphasis on performing this procedure in male patients.

    Materials And Methods: Review of the English PubMed/MEDLINE literature and specialty texts in cosmetic dermatology, oculoplastic, and facial aesthetic surgery regarding sex-specific use of chemical peels in men. Read More

    The Skin Bacterium Propionibacterium acnes Employs Two Variants of Hyaluronate Lyase with Distinct Properties.
    Microorganisms 2017 Sep 12;5(3). Epub 2017 Sep 12.
    Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
    Hyaluronic acid (HA) and other glycosaminoglycans are extracellular matrix components in the human epidermis and dermis. One of the most prevalent skin microorganisms, Propionibacterium acnes, possesses HA-degrading activity, possibly conferred by the enzyme hyaluronate lyase (HYL). In this study, we identified the HYL of P. Read More

    Fractional carbon dioxide laser for the treatment of facial atrophic acne scars: prospective clinical trial with short and long-term evaluation.
    Lasers Med Sci 2017 Sep 11. Epub 2017 Sep 11.
    Department of Dermatology and Venereology, Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey.
    The aim of this study was to evaluate the efficacy and safety of fractional carbon dioxide laser for the treatment of acne scars. Thirty-one participants, 15 female and 16 male, whose mean age was 34.84 ± 10. Read More

    Acne Scars: How Do We Grade Them?
    Am J Clin Dermatol 2017 Sep 11. Epub 2017 Sep 11.
    Department of Dermatology, University of California, Davis, 3301 C Street, Suite 1400, Sacramento, CA, 95816, USA.
    Acne vulgaris is a chronic inflammatory skin disease that can lead to permanent scarring. Although grading scales exist for acne scarring, there are many limitations, and there is still a need for a well validated gold standard scale for use in clinical practice or research trials. An objective measure of scar severity should be a component of global acne severity evaluations. Read More

    Potential Role of Curcumin Against Biofilm-Producing Organisms on the Skin: A Review.
    Phytother Res 2017 Sep 7. Epub 2017 Sep 7.
    Department of Dermatology, University of California, Davis, 3301 C Street, Suite 1400, Sacramento, CA, USA.
    Turmeric root (Curcuma longa) is predominantly used as a spice, but has also long been known to possess antimicrobial, analgesic, antiinflammatory, and anticancer properties. One predominant group of active compounds in turmeric are curcuminoids, namely bright yellow-pigmented curcumin. While modern science has yet to fully investigate the therapeutic claims of turmeric and its derivatives, results have proven promising in decreasing pain and inflammation in arthritis, improving insulin sensitivity in diabetes, and even curing a variety of infections. Read More

    Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation.
    Inflammation 2017 Sep 5. Epub 2017 Sep 5.
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
    Inflammatory responses induced by Propionibacterium acnes are a major etiological factor in the pathogenesis of acne vulgaris. Schisandrin A, schisandrin B, and schisandrin C are the representative lignans of Schisandra chinensis (Turcz.) Baill. Read More

    Comparison of salicylic acid 30% peel and pneumatic broadband light in the treatment of mild to moderately severe facial acne vulgaris.
    Cutis 2017 Jul;100(1):43-48
    Department of Dermatology, Perelman School of Medicine at University of Pennsylvania, Philadelphia, and Penn Medicine Radnor, Pennsylvania, USA.
    Acne patients experience not only a medical disease but also an aesthetic condition, and this latter complication greatly motivates patients to seek out the best treatment regimen to hasten improvement in their appearance. The available clinical procedures for acne treatment include salicylic acid 30% peel and pneumatic broadband light (PBBL). The objective of this study was to compare the efficacy of salicylic acid 30% peel and PBBL treatments in patients with mild to moderately severe facial acne vulgaris. Read More

    Translation and Validation of the Serbian Version of the Skindex-29 Instrument for Measuring Impact of Skin Disease on Quality of Life.
    Acta Dermatovenerol Croat 2017 Jul;25(2):120-127
    Prof. Slobodan M. Jankovic, MD, DSc, MSc, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica Street 69, 34000 Kragujevac, Serbia;
    The Skindex-29 instrument, which is intended for measuring the influence of skin diseases on quality of life, was developed and validated in several languages. However, a Serbian translation of the instrument is not available. The aim of this study was to translate the Skindex-29 from English to Serbian, to make necessary cultural adaptations, and to test its psychometric properties in a sample of outpatients with various skin diseases. Read More

    Physicochemical Screening and Shelf Life Evaluation of Kuṅkumādi Ghṛta Prepared using Kesara and Nāgakesara.
    Anc Sci Life 2017 Jan-Mar;36(3):129-135
    Department of Rasashastra and Bhaishajya Kalpana including Drug Research, I.P.G.T. and R.A., G.A.U, Jamnagar, Gujarat, India.
    Introduction: Kuṅkumādi Ghṛta (KG) is an Ayurvedic formulation commonly recommended in skin disorders, especially Mukhadūṣikā (Acne vulgaris). Kesara (stigma of Crocus sativus Linn.) is a prime ingredient in the formulation. Read More

    Dietary Supplements, Isotretinoin, and Liver Toxicity in Adolescents: A Retrospective Case Series.
    Pediatrics 2017 Oct 1;140(4). Epub 2017 Sep 1.
    University of California, San Diego/Rady Children's Hospital, San Diego, California.
    Isotretinoin is the most effective acne therapy available, but has the potential for a number of adverse side effects, including transaminitis. The iPLEDGE isotretinoin program recommends avoiding some herbals and supplements due to potential side effects. However, little is known about the effects of protein supplements on the liver, particularly in patients taking isotretinoin. Read More

    Chronic cutaneous lupus erythematosus presenting as atypical acneiform and comedonal plaque: case report and literature review.
    Lupus 2017 Jan 1:961203317726377. Epub 2017 Jan 1.
    Hospital do Servidor Público Municipal de São Paulo (HSPM), São Paulo, Brazil.
    Introduction Chronic cutaneous lupus erythematosus (CCLE) usually presents as characteristic erythematous patches and infiltrated coin-shaped plaques. However, there are some atypical clinical variants that may mimic other dermatological conditions. Haroon et al. Read More

    Predictive value of serum markers for postacne scarring.
    J Cosmet Dermatol 2017 Aug 30. Epub 2017 Aug 30.
    Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Benha, Egypt.
    Background: Postacne scarring is the main concern of many acne patients. Predicting the liability to scarring can alter the management protocols and help in preventing such disfigurement.

    Methods: Sixty patients with moderate to severe acne vulgaris (according to Global Acne Grading system) were included, only 35 of them had postacne scars. Read More

    The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming.
    World Allergy Organ J 2017 22;10(1):29. Epub 2017 Aug 22.
    In-FLAME Global Network, of the World Universities Network (WUN), West New York, USA.
    Skin barrier structure and function is essential to human health. Hitherto unrecognized functions of epidermal keratinocytes show that the skin plays an important role in adapting whole-body physiology to changing environments, including the capacity to produce a wide variety of hormones, neurotransmitters and cytokine that can potentially influence whole-body states, and quite possibly, even emotions. Skin microbiota play an integral role in the maturation and homeostatic regulation of keratinocytes and host immune networks with systemic implications. Read More

    Evaluation of autologous platelet rich plasma plus ablative carbon dioxide fractional laser in the treatment of acne scars.
    J Cosmet Laser Ther 2017 Aug 30. Epub 2017 Aug 30.
    a Department of Dermatology and Venerology (Laser Unit), Al-Hussein Hospital, Faculty of Medicine , Al- Azhar University , Cairo , Egypt.
    Introduction: Acne scar is a common distressing complication of acne vulgaris. CO2 laser resurfacing proved effective for treatment of such problem but the associated complications may limit its use. Platelet rich plasma (PRP) may increase the chance of favorable outcome. Read More

    Racial disparities in the management of acne: evidence from the National Ambulatory Medical Care Survey, 2005-2014.
    J Dermatolog Treat 2017 Sep 11:1-3. Epub 2017 Sep 11.
    a Department of Dermatology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
    Purpose: Racial health disparities are widespread in the United States, but little is known about racial disparities in the management of dermatological conditions.

    Materials And Methods: Nationally representative data on the management of acne vulgaris were gathered from the National Ambulatory Medical Care Survey (NAMCS) for the years 2005-2014. Visits to any specialist were included. Read More

    Management of severe acne during pregnancy: A case report and review of the literature.
    Int J Womens Dermatol 2017 Sep 13;3(3):145-150. Epub 2017 Jul 13.
    Department of Dermatology, University of Connecticut Health Center, Farmington, CT.
    The treatment of acne during pregnancy is often limited by the potential toxicities that are posed to the fetus by the most common and effective acne therapies. As with all dermatoses during pregnancy, the treatment of acne vulgaris in this population requires a thorough understanding of the risks and benefits that are inherent to each treatment. We report on a case of a 30-year-old pregnant patient with severe acne conglobata who showed significant improvement with a combination treatment of topical modalities, oral metronidazole, and low dose prednisone during pregnancy. Read More

    Evaluation of Anti-inflammatory and Antimicrobial Activity of AHPL/AYCAP/0413 Capsule.
    Pharmacognosy Res 2017 Jul-Sep;9(3):273-276
    Manager - Analytical Department, R & D Center, Ari Healthcare Private Limited, Unit No. 401, International Biotech Park, BTS 2 Building, Chrysalis Enclave, 4 Floor, Plot No - 2A, MIDC Phase II, Hinjewadi, Pune, Maharashtra, India.
    Background: Conventional therapeutic agents used for treatment of Acne are associated with various adverse effects necessitating development of safe and effective alternative therapeutic agents. In this context, a polyherbal formulation AHPL/AYCAP/0413 was developed for treatment of Acne.

    Objectives: To evaluate Anti-inflammatory and antimicrobial activity of AHPL/AYCAP/0413. Read More

    Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer.
    Nutr Metab (Lond) 2017 15;14:55. Epub 2017 Aug 15.
    Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Am Finkenhügel 7a, D-49076 Osnabrück, Germany.
    There is accumulating evidence that milk shapes the postnatal metabolic environment of the newborn infant. Based on translational research, this perspective article provides a novel mechanistic link between milk intake and milk miRNA-regulated gene expression of the transcription factor p53 and DNA methyltransferase 1 (DNMT1), two guardians of the human genome, that control transcriptional activity, cell survival, and apoptosis. Major miRNAs of milk, especially miRNA-125b, directly target TP53 and complex p53-dependent gene regulatory networks. Read More

    Sebocytes contribute to skin inflammation by promoting the differentiation of Th17 cells.
    Br J Dermatol 2017 Aug 11. Epub 2017 Aug 11.
    ZAUM - Center for Allergy and Environment, Technische Universität and Helmholtz Center Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
    Background: The main function of sebocytes is considered to be the lipid production for moisturizing the skin. However, it became recently apparent that sebocytes release chemokines and cytokines and respond to pro-inflammatory stimuli as well as presence of bacteria.

    Objectives: To analyze the functional communication between human sebocytes and T cells. Read More

    Propionibacterium acnes and the Th1/Th17 Axis, Implications in Acne Pathogenesis and Treatment.
    Indian J Dermatol 2017 Jul-Aug;62(4):392-394
    Department of Dermatology & STD, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
    Acne vulgaris is one of the most commonly seen conditions and the immunological link is a topic of active research. Recently, the Th17 pathway has been found to play a pivotal role in acne. The adaptive immune response toward Propionibacterium acnes leads to activation of Th17 axis. Read More

    The oral adverse effects of isotretinoin treatment in acne vulgaris patients: A prospective, case-control study.
    Niger J Clin Pract 2017 Jul;20(7):860-866
    Department of Operative Dentistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
    Background: Isotretinoin is the most effective therapy to treat severe acne vulgaris and its systemic adverse effects have been well documented, but little is known on dental side effects over the course of treatment.

    Objectives: This prospective case-control study aimed to evaluate the oral adverse effects of isotretinoin in Turkish patients with acne vulgaris; compare oral conditions between patients and normal controls; and investigate the association between salivary parameters and International Caries Detection and Assessment System (ICDAS) scores.

    Materials And Methods: For 6 months, the patients (n = 45) received isotretinoin daily (0. Read More

    Clinical efficacy and safety of benzoyl peroxide for acne vulgaris: Comparison between Japanese and Western patients.
    J Dermatol 2017 Aug 9. Epub 2017 Aug 9.
    Data Science Department, Maruho Co. Ltd, Kyoto, Japan.
    Benzoyl peroxide (BPO) has been well established as a common medication for acne vulgaris in many countries (e.g. in Europe and the USA), where clinical data have been accumulated over a long time. Read More

    Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients.
    Front Microbiol 2017 25;8:1381. Epub 2017 Jul 25.
    Joseph Banks Laboratories, School of Life Sciences, University of LincolnLincoln, United Kingdom.
    Emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in medicine especially in dermatology contexts where long term treatment with antibiotics is common. Remarkably, non-antibiotic therapy in the form of isotretinoin - a non-antimicrobial retinoid is effective at reducing or eradicating the anaerobe Propionibacterium acnes which is causally involved in the complex pathogenesis of Acne vulgaris. This study measured the extent of colonization of P. Read More

    Type 2 Minocycline-induced hyperpigmentation successfully treated with the novel 755 nm picosecond alexandrite laser - a case report.
    Laser Ther 2017 Jun;26(2):137-144
    Department of Dermatology, Keio University School of Medicine.
    Background And Aim: Minocycline therapy for acne vulgaris is associated with the occasional induction of various types of unsightly and often persistent hyperpigmentation, which is frequently resistant to hydroquinone treatment. Pigment-specific lasers have achieved some success with multiple treatment sessions. Recently, the picosecond domain 755 nm alexandrite laser (ps-Alex) has attracted attention in tattoo removal. Read More

    Laser treatments of active acne.
    Lasers Med Sci 2017 Aug 4. Epub 2017 Aug 4.
    The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, 10016, USA.
    The utility of laser therapy is increasingly being recognized in the treatment of active acne vulgaris. We aimed to perform a narrative review of the medical literature on the use of laser therapy for the treatment of active acne vulgaris. We performed a PubMed literature search on September 1, 2016 using the search terms "active acne," "acne," "laser therapy," and "laser surgery. Read More

    Acne Fulminans: Treatment Experience from 26 Patients.
    Dermatology 2017 29;233(2-3):136-140. Epub 2017 Jul 29.
    Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Dessau, Germany.
    Background /Aim: Acne fulminans is a rare form of acne vulgaris with acute clinical deterioration including systemic signs. Etiopathogenesis and management remain largely unknown. Our aim is to assess the efficacy of a combined therapeutic regimen of systemic isotretinoin and prednisolone following the recent concepts of acne pathogenesis and drug kinetics. Read More

    Treatment of Facial Acne Scarring With Fractional Carbon Dioxide Laser in Asians, a Retrospective Analysis of Efficacy and Complications.
    Dermatol Surg 2017 Sep;43(9):1137-1143
    *All authors are affiliated with the National Skin Centre, Singapore.
    Background: Fractional carbon dioxide (CO2) laser resurfacing unites the idea of fractional photothermolysis with an ablative 10,600-nm wavelength. This technology permits effective treatment of acne scarring, with shorter recovery and a decreased side effect profile as compared to traditional CO2 laser resurfacing.

    Objective: The aims of this study were to study the efficacy and safety of fractional CO2 laser for acne scars in Asian patients. Read More

    Evaluation of sequential effect of isotretinoin on the haematological parameters in patients with acne vulgaris.
    Cutan Ocul Toxicol 2017 Aug 9:1-4. Epub 2017 Aug 9.
    a Department of Dermatology, Faculty of Medicine , Celal Bayar University , Manisa , Turkey.
    Purpose: Isotretinoin is the most effective drug for acne with some side effects. Few studies exist regarding the effects of isotretinoin on haematological parameters with different results. Mostly, baseline values with a single value during or at the end of the treatment were compared. Read More

    Optimization of genotypic and biochemical methods to profile P. acnes isolates from a patient population.
    J Microbiol Methods 2017 Oct 18;141:17-24. Epub 2017 Jul 18.
    Microbiology Department, Faculty of Sciences, C/Fuentenueva s/n. University of Granada, 18071 Granada, Spain. Electronic address:
    Propionibacterium acnes is a key factor in the pathogenesis of acne vulgaris, although currently it is also being associated with medical-device infections. The aim of this work was to validate a safe and quick identification and typing of 24 clinical isolates of Propionibacterium acnes, applying a range of biochemical as well as genetic methods, and investigating the pathogenic potential to associate the different types with human health. RAPD-PCRs revealed the existence of two discernible clusters in correspondence with the phylogroups I and II, according to the PAtig gene polymorphism, leading them to be assigned as P. Read More

    Acne prevalence and associations with lifestyle: a cross-sectional online survey of adolescents/young adults in 7 European countries.
    J Eur Acad Dermatol Venereol 2017 Jul 14. Epub 2017 Jul 14.
    Pierre Fabre Dermatologie, Les Cauquillous, Lavaur, France.
    Background: Although acne vulgaris is a common skin disorder, limited epidemiological data exist specifically for European populations.

    Objective: To determine the prevalence of self-reported acne among young people in Europe and evaluate the effect of lifestyle on acne.

    Methods: We conducted a cross-sectional population-based online survey in representative samples of individuals aged 15-24 years in Belgium, Czech and Slovak Republics, France, Italy, Poland and Spain (n = 10 521), identified by a quota sampling method based on age, geographic location and socio-professional category. Read More

    The effect of personal, familial, and environmental characteristics on acne vulgaris: a prospective, multicenter, case controlled study from Turkey.
    G Ital Dermatol Venereol 2017 07 11. Epub 2017 Jul 11.
    Ankara University, School of Medicine, Department of Dermatology, Ankara, Turkey.
    Background: There are only a few studies about epidemiological features of acne vulgaris in the literature. The aim of this study was to analyze demographic, clinical, familial and environmental characteristics of acne, the role of diet and aggravating factors and association of these factors with acne severity.

    Methods: Patients with a diagnosis of mild-moderate to severe acne were consecutively interviewed at the participating centers during the study period. Read More

    Microneedling: Where do we stand now? A systematic review of the literature.
    J Plast Reconstr Aesthet Surg 2017 Jun 17. Epub 2017 Jun 17.
    Department of Plastic and Reconstructive Surgery - Burn Center, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium.
    Background: Patients who suffer from scars or wrinkles have several therapeutic options to improve the appearance of their skin. The available treatment modalities that provide desirable results are often overtly invasive and entail a risk of undesirable adverse effects. Microneedling has recently emerged as a non-ablative alternative for treating patients who are concerned with the aesthetic changes that result from injury, disease or ageing. Read More

    Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu.
    J Drugs Dermatol 2017 Jun;16(6):591-598

    BACKGROUND: Acne vulgaris has varying physical and psychological effects in men and women of different ages, races, and ethnicities.

    OBJECTIVE: This analysis assessed the relationship of age, sex, and race to treatment response with once-daily topical dapsone gel, 7.5%. Read More


    Adapalene/Benzoyl Peroxide Gel 0.3%/2.5%: Effective Acne Therapy Regardless of Age or Gender.
    J Drugs Dermatol 2017 Jun;16(6):582-589

    BACKGROUND: Acne vulgaris affects a diverse group of people, and there is an increasingly wide variety of acne treatments. Because of the many options, clinicians have a better ability to individualize treatment; however, achieving optimal results relies on understanding how various agents perform in specific population segments. Fixed-combination adapalene plus benzoyl peroxide (A/BPO) is a first-line recommended acne therapy and is available in two adapalene concentrations (0. Read More


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