Search our Database of Scientific Publications and Authors

I’m looking for a

    11629 results match your criteria Acne Vulgaris

    1 OF 233

    Immunohistochemical Expression of Cyclo-oxygenase 2 and Liver X Receptor-α in Acne Vulgaris.
    J Clin Diagn Res 2017 Sep 1;11(9):WC01-WC07. Epub 2017 Sep 1.
    Dermatology Specialist, Faculty of Medicine, Menoufiya University, Shibeen El Koom, Egypt.
    Introduction: Acne Vulgaris (AV) is a common inflammatory disease of pilosebaceous units. Liver X Receptor-α (LXR-α) is a ligand activated transcription factor. It controls transcription of genes involved in lipid and fatty acid synthesis. Read More

    Acne in late adolescence and risk of prostate cancer.
    Int J Cancer 2017 Dec 4. Epub 2017 Dec 4.
    Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.
    Accumulating evidence suggest that Propionibacterium acnes may play a role in prostate carcinogenesis, but data are so far limited and inconclusive. The aim of this population-based cohort study was therefore to test whether presence of acne vulgaris during late adolescence is associated with an increased risk of prostate cancer later in life. We identified a large cohort of young men born in Sweden between 1952 and 1956, who underwent mandatory assessment for military conscription around the age of 18 (n= 243,187). Read More

    Prevalence of Flp Pili-Encoding Plasmids in Cutibacterium acnes Isolates Obtained from Prostatic Tissue.
    Front Microbiol 2017 16;8:2241. Epub 2017 Nov 16.
    Department of Biomedicine, Aarhus University, Aarhus, Denmark.
    Inflammation is one of the hallmarks of prostate cancer. The origin of inflammation is unknown, but microbial infections are suspected to play a role. In previous studies, the Gram-positive, low virulent bacterium Cutibacterium (formerly Propionibacterium) acnes was frequently isolated from prostatic tissue. Read More

    G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes.
    Ann Dermatol 2017 Dec 30;29(6):688-698. Epub 2017 Oct 30.
    Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
    Background: Acne vulgaris is a disease of the pilosebaceous unit characterized by increased sebum production, hyperkeratinization, and immune responses to Propionibacterium acnes (PA). Here, we explore a possible mechanism by which a lipid receptor, G2A, regulates immune responses to a commensal bacterium.

    Objective: To elucidate the inflammatory properties of G2A in monocytes in response to PA stimulation. Read More

    Evaluation of the effects of acne vulgaris on quality of life in Turkey by using TAQLI.
    J Cosmet Dermatol 2017 Dec 4;16(4):485-490. Epub 2016 Nov 4.
    Department of Statistics, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
    Background: Acne vulgaris (AV) is a chronic, inflammatory skin disease that may cause various psychiatric and/or psychological problems.

    Objective: In this study, we aimed to determine the effect of AV on the quality of life in the Turkish population using the Turkish Acne Quality of Life Index (TAQLI).

    Methods: A total of 960 patients with AV who attended the dermatology department were included in the study. Read More

    Acne across Europe: an online survey on perceptions and management of acne.
    J Eur Acad Dermatol Venereol 2017 Dec 1. Epub 2017 Dec 1.
    Pierre Fabre Dermatologie, Les Cauquillous, Lavaur, France.
    Background: Acne is common among young people.

    Objective: To describe the burden, management and sources of advice, of acne in a representative sample of young people in Europe.

    Methods: This cross-sectional survey was conducted in a representative sample of individuals aged 15-24 years from Belgium, Czech and Slovak Republics, France, Italy, Poland and Spain (n=3099). Read More

    The role of zinc in the treatment of acne: A review of the literature.
    Dermatol Ther 2017 Nov 28. Epub 2017 Nov 28.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
    Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages. The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Read More

    A new optical intra-tissue fiber irradiation ALA-PDT in the treatment of acne vulgaris in rabbit model: improved safety and tolerability.
    An Bras Dermatol 2017 May-Jun;92(3):350-355
    Institute of Dermatology and Venereology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital - Chengdu, China.
    Background: Photodynamic therapy with topical aminolevulinic acid (ALA-PDT) has been suggested to be effective in treatment of acne vulgaris. However, adverse events occur during and after treatment.

    Objectives: To compare the efficacy and tolerability of optical intra-tissue fiber irradiation (OFI) ALA-PDT versus traditional ALA-PDT in treatment of acne vulgaris in rabbit models. Read More

    Dermatologic manifestations of endocrine disorders.
    Transl Pediatr 2017 Oct;6(4):300-312
    The Ohio State University College of Medicine, Columbus, OH, USA.
    The skin serves as a window for clinicians to understand, diagnose, and monitor endocrine disease. Dermatologic manifestations of endocrinopathies contribute significantly to an individual's health and quality of life. In this review, we outline various disorders of the hypothalamic-pituitary axis, thyroid gland, pancreas, adrenal gland, and androgen axis as well as hereditary endocrine syndromes. Read More

    Clinical behavior of a cohort of adult women with facial acne treated with combined oral contraceptive: ethinylestradiol 20 µg/dienogest 2 mg.
    Int J Womens Health 2017 16;9:835-842. Epub 2017 Nov 16.
    Support for Research, Academic, Scientific and Technological Services (SEACIT), Cali, Colombia.
    Acne vulgaris is the most common skin disease. It affects the young adult female population and generates great impact on physical and mental health. One of the treatments with good results for affected women is combined oral contraceptive pills (COCPs). Read More

    Novel device-based acne treatments: comparison of a 1,450-nm diode laser and micro-needling radiofrequency on mild to moderate acne vulgaris and seborrhea in Korean patients through a 20-week prospective, randomized, split-face study.
    J Eur Acad Dermatol Venereol 2017 Nov 24. Epub 2017 Nov 24.
    Department of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.
    Background: While device-based acne treatments are widely applied for patients not tolerating conventional medications, related controlled studies have been still limited. Recently, non-ablative 1,450-nm diode laser (DL) and fractional micro-needling radiofrequency (FMR) have been effectively used for acne, in addition to well-recognized dermal remodeling effects.

    Objective: To compare the clinical course for acne treatment between DL and FMR. Read More

    Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris.
    J Cosmet Dermatol 2017 Nov 21. Epub 2017 Nov 21.
    Department of Dermatology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
    Background: Superficial chemical peels are frequently used in acne vulgaris treatment. Although glycolic acid (GA) has been widely used in clinical practice, its pH ranges from 0.08-2. Read More

    Serum homocysteine levels in acne patients.
    J Cosmet Dermatol 2017 Nov 21. Epub 2017 Nov 21.
    Department of Dermatology, Clinical Research Center, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
    Objective: This study was designed to investigate serum homocysteine (HCY) levels in acne patients.

    Methods: Acne patients (n = 124) and healthy volunteers (n = 70), matched in terms of both age and sex, were enrolled. Serum HCY levels for all subjects were measured by a clinical laboratory. Read More

    Clinical effects of Zingiber cassumunar (Plai): A systematic review.
    Complement Ther Med 2017 Dec 7;35:70-77. Epub 2017 Oct 7.
    Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; School of Pharmacy, Monash University Malaysia, Selangor, Malaysia; School of Pharmacy, University of Wisconsin, Madison, USA; Asian Centre for Evidence Synthesis in Population, Implementation and Clinical Outcomes (PICO), Health and Well-being Cluster, Global Asia in the 21st Century (GA21) Platform, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia. Electronic address:
    Zingiber cassumunar Roxb. known locally as "Plai" in Thai, has been used for treating bruise, sprain and musculoskeletal pain. Several pre-clinical studies demonstrated the anti-inflammatory effect of Plai. Read More

    An extension of a multicenter, randomized, split-face clinical trial evaluating the efficacy and safety of chromophore gel-assisted blue light phototherapy for the treatment of acne.
    Int J Dermatol 2017 Nov 20. Epub 2017 Nov 20.
    1st Department of Dermatology, Andreas Syggros Hospital, University of Athens, Athens, Greece.
    A variety of laser/light-based devices have been reported to be effective for the treatment of acne, yet no long-term data on efficacy and safety have been published. A first 12-week clinical trial ("Main trial") recently demonstrated that the KLOX BioPhotonic System, an LED blue light device using photo-converter chromophores, can significantly improve moderate and severe facial acne vulgaris with an excellent safety profile. This Extension trial followed the Main trial, using the same BioPhotonic System, with the same dose and instructions for use, on patients having already completed treatment in the Main trial. Read More

    Exacerbation of Behçet's syndrome and familial Mediterranean fever with menstruation.
    Clin Exp Rheumatol 2017 Oct 24. Epub 2017 Oct 24.
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey.
    Obectives: Menstruation triggers several conditions such as migraine, recurrent aphthous stomatitis and acne vulgaris in healthy individuals. There is evidence that Behçet's syndrome (BS) and familial Mediterranean fever (FMF) may exacerbate during menstruation. The aim is to assess whether BS and FMF patients experience menstrual flares. Read More

    Lasers, Light, and the Treatment of Acne: A Comprehensive Review of the Literature.
    J Drugs Dermatol 2017 Nov;16(11):1095-1102
    Introduction: Acne vulgaris is common dermatologic condition with an estimated prevalence of 70 to 87%. Acne has been shown to have a significant impact on patient quality of life and mental health, especially as inflammatory lesions typically occur on cosmetically sensitive areas with the potential for permanent scarring. There have been numerous advances in the treatment of inflammatory acne with light-based and laser devices. Read More

    Pityrosporum Folliculitis: A Retrospective Review of 110 Cases.
    J Am Acad Dermatol 2017 Nov 11. Epub 2017 Nov 11.
    Department of Dermatology University of Massachusetts Medical School, Worcester, Massachusetts.
    Background: Pityrosporum folliculitis is an under-recognized eruption of the face and upper trunk that may be confused with, or occur simultaneously with, acne vulgaris.

    Objective: We sought to characterize risk factors for Pityrosporum folliculitis, its clinical presentation, and response to treatment.

    Methods: A retrospective chart review was performed on all patients aged 0 to 21 years seen from 2010-2015 with Pityrosporum folliculitis confirmed by potassium hydroxide (KOH) preparation. Read More

    Antiandrogenic and antimineralocorticoid health benefits of COC containing newer progestogens: dienogest and drospirenone.
    Oncotarget 2017 Oct 3;8(47):83334-83342. Epub 2017 Aug 3.
    Institut für Medizinische Forschung, Essen, Germany.
    Data have demonstrated that COCs, besides offering a satisfactory and safe contraception, offer a variety of non-contraceptive health benefits and therapeutic positive aspects. Many prescribes and users, however, do not realize these positive aspects especially the non-contraceptive health benefits. While the contraceptive use is the primary indication for COC use for most women, these users should be advised in regard of the non-contraceptive benefits when contraception is discussed and prescribed. Read More

    A comparative study of biological and metabolic biomarkers between healthy individuals and patients with acne vulgaris: A cross-sectional study protocol.
    Medicine (Baltimore) 2017 Nov;96(45):e8554
    aDepartment of Ophthalmology, Otolaryngology and Dermatology, College of Korean Medicine, Kyung Hee University bKorean Medicine Clinical Trial Center, Kyung Hee University Korean Medicine Hospital cCollege of Korean Medicine, Kyung Hee University dDepartment of Education, College of Education, Ewha Womans University, Seoul, Republic of Korea.
    Acne is a multifactorial dermatosis, which is influenced not only by hormones but also by the biochemical relationship between them and the pilosebaceous unit. Inflammatory cytokines, chemokines, active oxygen, and zinc are known to be associated with the development of acne. Further, steroid metabolism is known as one of the important factors related to sebum secretion and comedone formation in acne. Read More

    Utility of Gram staining for diagnosis of Malassezia folliculitis.
    J Dermatol 2017 Nov 13. Epub 2017 Nov 13.
    Department of Dermatology, Taipei Medical University Shuang Ho Hospital, New Taipei City, Taiwan.
    Malassezia folliculitis (MalF) mimics acne vulgaris and bacterial folliculitis in clinical presentations. The role of Gram staining in rapid diagnosis of MalF has not been well studied. In our study, 32 patients were included to investigate the utility of Gram staining for MalF diagnosis. Read More

    Pleiotropic Effects of White Willow Bark and 1,2-Decanediol on Human Adult Keratinocytes.
    Skin Pharmacol Physiol 2017 Nov 8;31(1):10-18. Epub 2017 Nov 8.
    Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
    Background: Acne vulgaris is a common skin defect, usually occurring during adolescence, but often it can persist in adults leaving permanent face scarring. Acne is usually treated with topical drugs, oral antibiotics, retinoids, and hormonal therapies, but medicinal plants are increasingly employed.

    Objective: To investigate the protective role of white willow bark (WWB) and 1,2-decanediol (DD) on the damage caused by lipopolysaccharides (LPS) on human adult keratinocytes (HaCaT). Read More

    Cutibacterium (formerly Propionibacterium) acnes infections associated with implantable devices.
    Expert Rev Anti Infect Ther 2017 Dec 17;15(12):1083-1094. Epub 2017 Nov 17.
    a Division of Infectious Diseases, Department of Internal Medicine , American University of Beirut Medical Center , Beirut , Lebanon.
    Introduction: Cutibacterium acnes (C. acnes), a Gram-positive biofilm-forming rod implicated in acne vulgaris, is increasingly recognized for its role in implant-associated infections. The diagnosis of C. Read More

    PPARγ Pro12Ala and C161T polymorphisms in patients with acne vulgaris: Contribution to lipid and lipoprotein profile.
    Adv Med Sci 2017 Nov 6;63(1):147-151. Epub 2017 Nov 6.
    Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Clinical Biochemistry, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:
    Purpose: The aim of present study was to clarify the role of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala and C161T variants in the pathogenesis of acne vulgaris (AV) and their influence on lipid and lipoprotein profile.

    Methods: The present case-control study consisted of 393 individuals including 198 patients with AV (mild-, moderate-, and severe-AV) and 195 unrelated age-matched healthy individuals from Western Iran. The PPARγ Pro12Ala and C161T polymorphisms were identified using polymerase chain reaction-restriction length polymorphism method. Read More

    Heritability and GWAS Analyses of Acne in Australian Adolescent Twins.
    Twin Res Hum Genet 2017 Dec 7;20(6):541-549. Epub 2017 Nov 7.
    QIMR Berghofer Medical Research Institute,Brisbane,QLD,Australia.
    Acne vulgaris is a skin disease with a multifactorial and complex pathology. While several twin studies have estimated that acne has a heritability of up to 80%, the genomic elements responsible for the origin and pathology of acne are still undiscovered. Here we performed a twin-based structural equation model, using available data on acne severity for an Australian sample of 4,491 twins and their siblings aged from 10 to 24. Read More

    The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris.
    Peptides 2017 Nov 3;99:36-43. Epub 2017 Nov 3.
    Marbio, Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT The Arctic University of Norway, N-9037 Tromsø, Norway. Electronic address:
    Propionibacterium acnes is a commensal bacterium, which is involved in acne inflammation. An antimicrobial peptide named CEN1HC-Br, which was isolated and characterized form the green sea urchin, has been shown to possess broad-spectrum antibacterial activity. Little is known concerning the potential effects of its antibacterial and anti-inflammatory properties against P. Read More

    Skin Surface pH in Acne Vulgaris: Insights from an Observational Study and Review of the Literature.
    J Clin Aesthet Dermatol 2017 Jul 1;10(7):33-39. Epub 2017 Jul 1.
    Drs. Prakash, P. Bhargava, Tiwari and Majumdar are with the Department of Dermatology, Venereology and Leprosy, Sawai Man Singh Medical College and Attached Hospitals, Jaipur, Rajasthan, India.
    OBJECTIVE: Recurrent and chronic course of acne vulgaris, despite effect-proven therapies, point to an underfocused aspect in its pathogenesis and management. This study aims to assess in subjects with and without acne, the skin surface pH, a parameter that cumulatively represents functioning of various units of skin, including the barrier. METHODS: A total of 200 patients with acne and 200 age- and sex-matched controls were included. Read More

    In-vitro evaluation of marine derived fungi against Cutibacterium acnes.
    Anaerobe 2017 Nov 10;49:5-13. Epub 2017 Nov 10.
    TERI-Deakin Nano Biotechnology Centre, Biotechnology and Management of Bioresources Division, The Energy and Resources Institute, New Delhi 110003, India. Electronic address:
    Cutibacterium acnes (or Propionibacterium acnes) is the main target for the prevention and medical treatment of acne vulgaris. The aim of this study was to evaluate the in vitro anti-C. acnes and anti-S. Read More

    Isotretinoin-induced Angle Closure and Myopic Shift.
    J Glaucoma 2017 Nov;26(11):e252-e254
    Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea.
    Purpose: To report and describe the management a rare case of transient bilateral angle closure with increased intraocular pressure (IOP) and myopic shift while on isotretinoin therapy for acne.

    Methods: A 28-year-old woman presented with bilateral myopic shift, angle closure with IOP increase, and supraciliary effusion 1 week after acne therapy with isotretinoin. Two weeks after stopping isotretinoin, and treatment with topical prednisolone acetate, atropine, and fixed combination of timolol and dorzolamide, refraction, IOP returned to normal and supraciliary effusions was decreased on ultrasound biomicroscopy. Read More

    Low-level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne.
    Lasers Surg Med 2017 Nov 2. Epub 2017 Nov 2.
    The Johnson & Johnson Skin Research Center, Johnson & Johnson Consumer Inc., Skillman, New Jersey.
    Background And Objective: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units (PSU), associated with increased sebum production, abnormal follicular keratinization (hyperkeratinization), follicular overgrowth of Propionibacterium acnes (P. acnes), and increased inflammatory mediator release. Light therapy has attracted medical interests as a safe alternative treatment for acne. Read More

    Visually augmented targeted combination light therapy for acne vulgaris: a case report.
    J Med Case Rep 2017 Oct 31;11(1):316. Epub 2017 Oct 31.
    Gordano School, Portishead, Bristol, UK.
    Background: Acne vulgaris is a common skin disease. Pharmacological modalities for treatment are proven to be efficacious but have limitations. Light therapy for acne vulgaris has shown promise in previous studies. Read More

    [Diet in pathogenesis of acne vulgaris].
    Pol Merkur Lekarski 2017 Oct;43(256):186-189
    Chair and Department of Histology and Embriology, Medical University of Warsaw.
    Acne vulgaris is one of the most common dermatologic condition especially among adolescents. Acne is related to excess sebum production by sebaceous glands, inflammation both within and adjacent to the comedones, hyperproliferation of Propionibacterium acnes. Some of investigations show association between acne and diet. Read More

    Antibacterial activity of gold nanorods against Staphylococcus aureus and Propionibacterium acnes: misinterpretations and artifacts.
    Int J Nanomedicine 2017 9;12:7311-7322. Epub 2017 Oct 9.
    Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy, The University of Jordan, Amman, Jordan.
    The antibacterial activity of gold nanorod (GNR) suspensions of different surface functionalities was investigated against standard strains of Staphylococcus aureus and Propionibacterium acnes, taking into consideration two commonly "overlooked" factors: the colloidal stability of GNR suspensions upon mixing with bacterial growth media and the possible contribution of "impurities/molecules" in GNR suspensions to the observed antibacterial activity. The results demonstrated that cationic polyallylamine hydrochloride (PAH)-GNR were severely aggregated when exposed to bacterial growth media compared to other GNR suspensions. In addition, the free cetyltrimethylammonium bromide (CTAB) present in GNR suspensions is most likely the origin of the observed antibacterial activity. Read More

    Chemical peels: A review of current practice.
    Australas J Dermatol 2017 Oct 24. Epub 2017 Oct 24.
    Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
    Chemical peels belong to a group of cutaneous resurfacing procedures that are used in the treatment of photoageing, inflammatory dermatoses, epidermal proliferations, pigmentary disorders and scarring. This review describes best current practice, highlights recent advances in chemical peel technology and discusses the recommended uses for different peel types. It also presents the results of a survey of the chemical peeling practices of 30 Australian dermatologists. Read More

    Topical ALA-PDT as alternative therapeutic option in treatment-recalcitrant dermatosis: Report of 4 cases.
    Photodiagnosis Photodyn Ther 2017 Dec 18;20:189-192. Epub 2017 Oct 18.
    Department of Dermatology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Electronic address:
    Background: Topical Photodynamic therapy (PDT) is widely acknowledged for its safety and effectiveness in treating oncologic skin diseases such as basal cell carcinoma, actinic keratosis and squamous cell carcinoma in situ. Despite its broad applications in dermatology, this method is a relatively new therapeutic option for treating inflammatory/infectious skin diseases.

    Objectives: To determine whether topical PDT is a safe and effective treatment option in treating treatment-recalcitrant dermatosis. Read More

    The Effect of Skin Sebum, pH, and Moisture on Demodex Infestation in Acne Vulgaris and Rosacea Patients.
    Turkiye Parazitol Derg 2017 Sep;41(3):143-147
    Özel Melid Park Hastanesi, Malatya, Türkiye.
    Objective: Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. Read More

    Efficacy and tolerability of liposomal polyvinylpyrrolidone-iodine hydrogel for the localized treatment of chronic infective, inflammatory, dermatoses: an uncontrolled pilot study.
    Clin Cosmet Investig Dermatol 2017 22;10:373-384. Epub 2017 Sep 22.
    Mundipharma Research GmbH & Co.KG, Limburg (Lahn), Germany.
    Infection is common in many chronic, inflammatory skin conditions but is often difficult to treat, in part due to growing bacterial resistance to antibiotics. Liposomal polyvinyl-pyrrolidone (PVP)-iodine hydrogel has a unique mode of action, combining the antiseptic and anti-inflammatory actions of PVP-iodine with the drug delivery and moisturizing properties of liposomes. We investigated the utility of liposomal PVP-iodine to treat infective dermatoses. Read More

    Network pharmacology-based approach of novel traditional Chinese medicine formula for treatment of acute skin inflammation in silico.
    Comput Biol Chem 2017 Dec 14;71:70-81. Epub 2017 Sep 14.
    Department of Medical Research, China Medical University Hospital, Taichung 40447, Taiwan; Department of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou 510275, China. Electronic address:
    Matrix metalloproteinase-9 (MMP-9) appears to play an important role in acute skin inflammation. Subantimicrobial dose of tetracycline has been demonstrated to inhibit the activity of MMP-9 protein. However, long-term use tetracycline will induce side effect. Read More

    Treatment of Moderate-to-severe Acne Vulgaris in a Hispanic Population: A Post-hoc Analysis of the Efficacy and Tolerability of Clindamycin 1.2%/Benzoyl Peroxide 3.75% Gel.
    J Clin Aesthet Dermatol 2017 Jun 1;10(6):36-43. Epub 2017 Jun 1.
    Valeant Pharmaceuticals North America LLC, Bridgewater, New Jersey.
    Background: Acne vulgaris (acne) is highly prevalent in the Hispanic population as it is in other racial/ethnic groups. While nuances in the presentation, quality-of-life impact, and approach to therapy of acne have been reported in various racial ethnic groups and skin types, data on the Hispanic population are limited, and yet they are the fastest growing population in the United States. Potential for irritation, dryness, and pigmentary alteration (due to acne and/or treatment) are key concerns in the management of acne in Hispanic populations. Read More

    Living with Acne: Belief and Perception in a Sample of Indian Youths.
    Indian J Dermatol 2017 Sep-Oct;62(5):491-497
    Department of Dermatology, MMIMSR, Ambala, Haryana, India.
    Background: Acne vulgaris is a common disease among adolescent. There is paucity of information on knowledge and understanding of acne patients about their condition.

    Objective: This study was carried out to evaluate beliefs and perception of acne patient toward their understanding of disease, treatment option, and information source. Read More

    Psychosocial impact of acne and postinflammatory hyperpigmentation.
    An Bras Dermatol 2017 Jul-Aug;92(4):505-509
    Department of Psychiatry and Behavioral Sciences; University of Miami Miller School of Medicine - Miami (FL), USA.
    Background:: Acne is one of the most common skin diseases. It has significant effect on self-image and negative impact on quality of life. Postinflammatory hyperpigmentation is an acquired hypermelanosis that occurs after a skin injury or cutaneous inflammation. Read More

    Relationship between acne vulgaris and cosmetic usage in Sri Lankan urban adolescent females.
    J Cosmet Dermatol 2017 Sep 22. Epub 2017 Sep 22.
    Faculty of Medicine, Medical Education Development and Research Centre, University of Colombo, Colombo, Sri Lanka.
    Background: Acne vulgaris is one of the commonest skin disorders affecting up to 80% of the world population at least during adolescence. Significant psychosocial effects such as depression and poor personality development have been linked with acne, especially in female adolescents. Various causative factors, including cosmetic exposure, have been attributed toward acne. Read More

    Help-seeking behaviours, opportunistic treatment and psychological implications of adolescent acne: cross-sectional studies in schools and hospital outpatient departments in the UK.
    BMJ Open 2017 Sep 21;7(9):e016964. Epub 2017 Sep 21.
    Department of Adolescent Endocrinologist, University College London Hospitals NHS Foundation Trust, London, UK.
    Background: Acne vulgaris (acne) is a common adolescent skin condition. It is associated with negative psychological impacts and sufferers do not easily seek help, hence is undertreated.

    Objectives: We investigated the self-reported prevalence, severity and psychological sequelae of acne, together with assessing help-seeking behaviour and its barriers, in separate school and hospital samples. Read More

    1 OF 233