13,354 results match your criteria Acne Vulgaris


[Effect of Gaseous Pollutant Concentration on the Number of Daily Outpatient Visits for Acne in Lanzhou].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Apr;43(2):180-187

Information Center,Lanzhou University Second Hospital,Lanzhou 730000,China.

Objective To determine the relationship between air pollutants [SO,NO,8 hours average concentration of ozone(O8h)] and outpatient visits for acne in Lanzhou,China. Methods Data of daily outpatient visits for acne and concentrations of air pollutants(SO,NO,and O8h)from January 2013 to December 2017 were collected.With the control of long-term trend and day-of-week effect,a distributed lag nonlinear model was used to analyze the lag and cumulative effects of air pollutants on the outpatient visits. Read More

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An increase in normetanephrine in hair follicles of acne lesions through the sympatho-adrenal medullary system in acne patients with anxiety.

J Dermatol 2021 May 7. Epub 2021 May 7.

Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.

Acne vulgaris, a chronic inflammatory skin disease, has been associated with not only sebaceous gland dysfunction but also various endogenous and exogenous stresses. Since sebaceous glands are under neuroendocrine control, including the hypothalamic-pituitary-adrenal axis and neuro-autocrine mechanisms, it remains unclear how psychological stress relates to the pathogenesis of acne. In this study, we investigated the relationship between psychological stress and catecholamine in acne lesions from 18 patients with mild or moderate acne. Read More

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Treatment challenges in adult female acne and future directions.

Expert Rev Clin Pharmacol 2021 May 7. Epub 2021 May 7.

Department of Specialized Medicine, Discipline of Dermatology - Universidade Federal do Piauí, Brazil.

Introduction: Acne is a chronic, inflammatory, and immune mediated disease of the pilosebaceous unit, highly prevalent in adolescents. However, an increasing number of adults over 25 years old with facial acne, particularly women, have been observed. It is considered a different disease when compared to acne vulgaris. Read More

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Effects of ısotretinoin on the growth rate and thickness of the nail plate.

Int J Dermatol 2021 May 5. Epub 2021 May 5.

Department of Dermatology, Balıkesir University Faculty of Medicine, Balikesir, Turkey.

Background: Isotretinoin has various effects on nails. However, the mechanism of how isotretinoin affects the nail plate is unknown. We aimed to investigate the effects of isotretinoin on morphology, growth rate, and thickness of the nail plate. Read More

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Self-limited acne agminate-like granulomatous reaction to facial laser rejuvenation in a patient with comedonal acne vulgaris.

J Cosmet Laser Ther 2021 May 4:1-3. Epub 2021 May 4.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Minimally invasive fractional rejuvenation was developed to overcome the drawbacks of the traditional ablative laser. The Fotona 4D laser is one of these lasers used for face lifting. This laser uses two wavelengths such as Nd-YAG 1064 and Er-YAG 2940 nm in four different modes of non-ablative and ablative fractional laser to induce bulk heating in different tissue layers of facial skin. Read More

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Home-based devices in dermatology: a systematic review of safety and efficacy.

Arch Dermatol Res 2021 May 3. Epub 2021 May 3.

Department of Dermatology, State University of New York, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY, 11203, USA.

There is increasing demand for home-based devices for the treatment of dermatologic conditions and cosmesis. Commercially available devices include intense pulsed light, laser diodes, radiofrequency, light-emitting diodes, and ultraviolet B phototherapy. The objective of this report is to evaluate the current evidence regarding the efficacy and safety of home-based devices for the treatment of skin conditions. Read More

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The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color.

Skinmed 2021 1;19(2):110-115. Epub 2021 Apr 1.

Department of Dermatology and Venerology, Faculty of Medicine, University of Hasanuddin, Makassar, South Sulawesi, Indonesia.

Post-acne hyperpigmentation (PAH) occurs secondary to acne vulgaris and may cause significant adverse effects. Although may occur in any skin types, PAH has been found to be more common and severe in people with colored skin. This study aimed to assess the effectiveness of combination serum containing galactomyces ferment filtrate (GFF), dexpanthenol, and for treating PAH. Read More

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A Deep Learning Based Framework for Diagnosing Multiple Skin Diseases in a Clinical Environment.

Front Med (Lausanne) 2021 16;8:626369. Epub 2021 Apr 16.

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Numerous studies have attempted to apply artificial intelligence (AI) in the dermatological field, mainly on the classification and segmentation of various dermatoses. However, researches under real clinical settings are scarce. This study was aimed to construct a novel framework based on deep learning trained by a dataset that represented the real clinical environment in a tertiary class hospital in China, for better adaptation of the AI application in clinical practice among Asian patients. Read More

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Awareness on Teratogenic Effects of Isotretinoin and Compliance with Precautionary Measures among Women of Childbearing Age in Makkah Province, Saudi Arabia.

Obstet Gynecol Int 2021 10;2021:9966300. Epub 2021 Apr 10.

East Jeddah General Hospital, Ministry of Health, Jeddah, Saudi Arabia.

Acne vulgaris ranks among the most common dermatologic conditions encountered during adolescence up to adulthood. For moderate to severe cases of acne, isotretinoin is indicated as it is considered the most efficacious medication against acne. However, isotretinoin use is known to have its side effects and most importantly is the drug's teratogenic potential. Read More

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Incidence and Clinical Implications of Autoimmune Thyroiditis in the Development of Acne in Young Patients.

Diagnostics (Basel) 2021 Apr 28;11(5). Epub 2021 Apr 28.

Department of Psycho-Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.

Autoimmune thyroiditis (AIT) is on the rise among the population, and is frequently associated with patients with acne vulgaris, especially females aged between 18-55 years old. The connection between the two is not fully elucidated. In this study, 236 patients diagnosed with acne in the dermatological office of the private Pelican Hospital and in few private dermatological offices from Oradea, Romania, during January 2018-December 2020, aged between 12 and 55 years old, were endocrinologically investigated to determine AIT and its influence on the severity of the acne. Read More

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Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris.

Pharmaceutics 2021 Apr 16;13(4). Epub 2021 Apr 16.

Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.

Acne vulgaris is a common, multifactorial, inflammatory skin disease affecting the pilosebaceous unit. Topical therapy is the first choice in the treatment of mild to moderate acne, and azelaic acid (AZA) is one of the most commonly used drugs. The aim of this study was to evaluate the safety and efficacy of a low-dose azelaic acid nanocrystal (AZA-NC) hydrogel in the treatment of mild to moderate facial acne. Read More

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Effects of CJLP55 on Clinical Improvement, Skin Condition and Urine Bacterial Extracellular Vesicles in Patients with Acne Vulgaris: A Randomized, Double-Blind, Placebo-Controlled Study.

Nutrients 2021 Apr 19;13(4). Epub 2021 Apr 19.

Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Gyeongggi-do, Korea.

CJLP55 has anti-pathogenic bacterial and anti-inflammatory activities in vitro. We investigated the dietary effect of CJLP55 supplement in patients with acne vulgaris, a prevalent inflammatory skin condition. Subjects ingested CJLP55 or placebo ( = 14 per group) supplements for 12 weeks in this double-blind, placebo-controlled randomized study. Read More

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A Correlation between Serum Level of Alkaline Phosphatase and Acne Severity in Children and Adolescents: A Retrospective Cross-Sectional Study.

Ann Dermatol 2020 Jun 24;32(3):206-212. Epub 2020 Apr 24.

Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea.

Background: Acne is a chronic inflammatory disease of the pilosebaceous unit and usually affects adolescents when the peak concentrations of growth hormone, insulin-like growth factor 1, and androgen are demonstrated. The activity of alkaline phosphatase (ALP), which increases physiologically in growing children and adolescents, in the pilosebaceous unit has been reported. However, the correlation between the serum level of ALP and the number of acne lesions has not been studied. Read More

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Sex Hormones, Metabolic Status, and Obesity in Female Patients with Acne Vulgaris Along with Clinical Correlation: An Observational Cross-Sectional Study.

Indian J Dermatol 2021 Jan-Feb;66(1):60-66

Department of Dermatology, Venereology and Leprosy, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.

Background: Acne vulgaris is a common dermatological disorder. Several hormones are suspected to play a role in its etiopathogenesis.

Aims And Objectives: The aim of this study was to analyze the role of sex-hormones, metabolic status, and obesity in acne vulgaris and correlate with its severity and symptom load. Read More

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Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist.

Authors:
Leon H Kircik

Expert Opin Pharmacother 2021 Apr 27:1-6. Epub 2021 Apr 27.

Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

: Increased circulating androgens are key to the multifactorial pathogenesis of acne. Clascoterone is the first topical androgen antagonist developed to treat acne in both male and female patients and the first such agent to receive U.S. Read More

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[Atypical keloids with an unusual myofibroblastic differentiation in a patient with acne vulgaris].

Hautarzt 2021 Apr 27. Epub 2021 Apr 27.

Haut- und Laserzentrum Heidelberg, Bergheimer Str. 56a, 69115, Heidelberg, Deutschland.

We present the case of a patient with a discreet acne and multiple keloids in the area of the upper trunk, histologically showing an unusual myofibroblastic differentiation. So far, the clinical course shows a poor response to the treatment, including cryotherapy, intralesional corticosteroid injections, occlusive silicone dressings and dye laser. Read More

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[Acne vulgaris].

MMW Fortschr Med 2021 04;163(8):58-65

CentroDerm GmbH, 42287, Wuppertal, Germany.

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[Scientometric analysis of evidence-based studies of physical methods of post-acne scar correction].

Authors:
I G Kurganskaya

Vopr Kurortol Fizioter Lech Fiz Kult 2021 ;98(2):45-54

Skin and venereal clinic N4, St.-Petersburg, Russia.

The scope of physical methods for correcting the pathological skin scars is rapidly growing but the results of their use are often unsatisfactory. An inadequate approach to therapy without taking into account the assessment of their effectiveness leads to relapses, increased growth of scar tissue or the absence of a clinically significant effect which requires strict scientific evidence in the course of benign scientific studies.

Objective: Scientometric analysis of evidence-based studies on the use of therapeutic physical factors in the correction of post-acne scars. Read More

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A review of Nigella sativa plant-based therapy in dermatology.

Int J Dermatol 2021 Apr 26. Epub 2021 Apr 26.

Veterans Affairs Medical Center, Brooklyn, NY, USA.

Nigella sativa (N. sativa) is a widely used medicinal herb with a rich cultural and religious history in Unani, Ayurveda, Chinese, and Arabic medicine. N. Read More

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Oral isotretinoin treatment in patients with acne vulgaris during the COVID-19 pandemic: A retrospective cohort study in a tertiary care hospital.

J Cosmet Dermatol 2021 Apr 22. Epub 2021 Apr 22.

Department of Dermatology and Venereology, Uşak University Training and Research Hospital, Uşak, Turkey.

Background: Patients with acne vulgaris continue to present increasingly in dermatology outpatient clinics and seek treatment during the COVID-19 pandemic. As far as we know, the effect of isotretinoin on COVID-19 has not been studied before.

Aim: We aimed to evaluate whether patients receiving oral isotretinoin are at increased risk of COVID-19 infection by comparing them with patients on topical treatment for acne vulgaris. Read More

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Role of Adenosine Deaminase in Patients with Erythematotelangiectatic Rosacea and Positivity.

Iran J Parasitol 2020 Oct-Dec;15(4):596-601

Department of Medical Microbiology, Faculty of Medicine, Giresun University, Giresun, Turkey.

Background: Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxyadenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. species have been reported to be transmitted between humans through close contact and to play a role in the pathogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micropapillary-pruritic dermatitis and blepharitis. Read More

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Comment on "Androgens and women: COVID-19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism".

Int J Dermatol 2021 Apr 20. Epub 2021 Apr 20.

Unit of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.

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A New Era for Truncal Acne: Emerging from a Legacy of Neglect.

Dermatol Ther (Heidelb) 2021 Apr 20. Epub 2021 Apr 20.

CentroDerm Clinic, Wuppertal, Germany.

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Why We Should Consider Evidence-Based Treatment Options for Truncal Acne.

Dermatol Ther (Heidelb) 2021 Apr 19. Epub 2021 Apr 19.

CentroDerm Clinic, Heinz-Fangman-Straße 57, 42287, Wuppertal, Germany.

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Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris.

Expert Opin Drug Deliv 2021 Apr 19. Epub 2021 Apr 19.

University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh, India 160 014.

: The combination therapy of Isotretinoin (ITR) and antibacterial formulations administered through topical route suffer from several limitations including reduced therapeutic efficacy and low patient-compliance.: The present study aimed to develop biocompatible lipid-based mixed micelles of ITR in combination with Clindamycin phosphate (CLIN) employing self-assembly method to improve its skin delivery, photostability, biocompatibility and pharmacodynamic efficacy.: The MTT assay and cellular uptake studies showed non-cytotoxic effect to HaCat cell lines. Read More

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Consumer preferences of top-rated over-the-counter acne treatment products: a cohort study.

Arch Dermatol Res 2021 Apr 17. Epub 2021 Apr 17.

Department of Dermatology, Temple University, Philadelphia, PA, USA.

Over 70% of patients with acne vulgaris wait at least 1 year before seeing a dermatologist and instead use over-the-counter (OTC) acne treatments. This study determined the association between product characteristics (ingredients, vehicles, and marketing claims) and consumer-reported positive and negative features of top-rated acne OTCs. This cohort study evaluated the top 1% of acne OTCs across the five largest online retailers. Read More

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Effectiveness of Wet Cupping on Patients with Facial Acne Vulgaris: A 12-Week, Randomized, Single-Blind, Intervention-Sham-Controlled Trial.

Complement Med Res 2021 Apr 16:1-8. Epub 2021 Apr 16.

Department of Internal and Integrative Medicine, Evang. Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany.

Introduction: Acne vulgaris is a widespread skin disorder. The aim of this study was to assess the effectiveness of wet cupping in the treatment of moderate to severe facial acne vulgaris.

Methods: Between August 2018 and January 2020, eligible patients with moderate to severe facial acne were recruited in this single-blind, intervention-sham-controlled clinical trial in Iran. Read More

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5-Aminolaevulinic acid photodynamic therapy amplifies intense inflammatory response in the treatment of acne vulgaris via CXCL8.

Exp Dermatol 2021 Apr 15. Epub 2021 Apr 15.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.

Acne vulgaris is a chronic inflammatory cutaneous disease. 5-Aminolaevulinic acid photodynamic therapy (ALA-PDT) is a novel and effective approach for severe acne vulgaris treatment. However, its specific treatment mechanism still remains unclear. Read More

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Excoriation (skin-picking) disorder among adolescents and young adults with acne-induced postinflammatory hyperpigmentation and scars.

Int J Dermatol 2021 Apr 16. Epub 2021 Apr 16.

Psychology Unit, Department of General Science and Maths, Prince Sultan University, Riyadh, Saudi Arabia.

A plethora of health-related concerns, including skin disorders, are particularly common during the critical periods of adolescence and young adulthood. Their reactions to skin-related disorders can be different from their reactions to other disorders. While medical problems could be physiologically impacting, skin disorders like excoriation disorder can, in addition, directly affect their physical appearance in ways that have psychological consequences like anxiety, low self-esteem, and impaired quality of life. Read More

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A New Approach to Harness Probiotics Against Common Bacterial Skin Pathogens: Towards Living Antimicrobials.

Probiotics Antimicrob Proteins 2021 Apr 15. Epub 2021 Apr 15.

DWI Leibniz-Institute for Interactive Materials, 52074, Aachen, Germany.

In this study, the potential of certain lactic acid bacteria-classified as probiotics and known to be antimicrobially active against pathogens or food-poisoning microorganisms-was evaluated with respect to their activity against bacterial skin pathogens. The aim of the study was to develop a plaster/bandage for the application of inhibitory substances produced by these probiotics when applied to diseased skin. For this purpose, two Streptococcus salivarius strains and one Lactobacillus plantarum were tested for production of antimicrobials (bacteriocin-like substances) active against Gram-positive and Gram-negative pathogens using established methods. Read More

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