1,811 results match your criteria Achilles Tendon Injuries and Tendonitis


How many runners with new-onset Achilles tendinopathy develop persisting symptoms? A large prospective cohort study.

Scand J Med Sci Sports 2020 Jul 2. Epub 2020 Jul 2.

Department of Orthopaedic Surgery and Sports Medicine, Erasmus MC, University Medical Center Rotterdam, Zuid-Holland, The Netherlands.

Background: Achilles tendinopathy(AT) occurs in half of elite runners. AT is a difficult to treat tendon disease, which may progress from new-onset to a chronic state. It is unknown how many runners with new-onset AT develop persisting symptoms and which prognostic factors are associated with this course. Read More

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http://dx.doi.org/10.1111/sms.13760DOI Listing

Current pharmacological approaches to the treatment of tendinopathy.

Expert Opin Pharmacother 2020 Jun 8:1-11. Epub 2020 Jun 8.

Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno , Baronissi, Italy.

Introduction: Tendinopathies are common in elite and recreational athletes: traditionally considered overuse injuries, they involve excessive tensile loading and subsequent breakdown of the loaded tendon. Many pharmacological treatments have been proposed for the management of tendinopathy, with no agreement regarding the overall best option available both for Achilles and patellar tendinopathy.

Areas Covered: The present article reports the best scientific evidence regarding the efficacy and safety of different pharmacological treatments in different types of tendinopathy, focusing on Achilles and patellar tendinopathy, the conditions on which more studies have been published. Read More

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http://dx.doi.org/10.1080/14656566.2020.1763306DOI Listing

Effect of low intensity photobiomodulation associated with norbixin-based poly (hydroxybutyrate) membrane on post-tenotomy tendon repair. In vivo study.

Acta Cir Bras 2020 22;35(3):e202000303. Epub 2020 May 22.

Postgraduate Program in Material Engineering (PPGEM), IFPI, Teresina, PI, Brazil.

Purpose: To evaluate the in vivo response of photobiomodulation therapy associated with norbixin-based poly(hydroxybutyrate) membrane (PHB) in tenotomized calcaneal tendon.

Methods: Thirty rats were randomly allocated to six groups (n=5 each): LED groups (L1, L2 and L3) and membrane + LED groups (ML1, ML2 and ML3). The right calcaneal tendons of all animals were sectioned transversely and were irradiated with LED daily, one hour after surgery every 24 hours, until the day of euthanasia. Read More

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http://dx.doi.org/10.1590/s0102-865020200030000003DOI Listing
June 2020
0.570 Impact Factor

Genetic factors in rotator cuff pathology: potential influence of col 5A1 polymorphism in outcomes of rotator cuff repair.

BMC Med Genet 2020 Apr 17;21(1):82. Epub 2020 Apr 17.

Department of Orthopaedics and Trauma Surgery, Campus Bio-Medico University of Rome, Rome, Italy.

Background: Investigations in genetics have provided valuable information about the correlation between gene variants and tendinopathy. Single Nucleotide Polymorphisms of COL5A1 gene are reported to be involved in Achilles tendinopathy, chronic degenerative tendon changes at the elbow, and other tendinopathies. The influence of Single Nucleotide Polymorphisms of COL5A1 was previously analyzed in rotator cuff disease with confounding results. Read More

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http://dx.doi.org/10.1186/s12881-020-01022-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165385PMC

Is genu varum a risk factor for the prevalence and severity of achilles tendinopathy? A cross-sectional study of Nigerian elite track and field athletes.

Niger Postgrad Med J 2020 Apr-Jun;27(2):87-92

Department of Physiotherapy, College of Medicine, University of Lagos, Lagos, Nigeria.

Background: Achilles tendinopathy (AT) is one of the most frequently reported ankle and foot overuse injuries. Prior studies have reported altered biomechanical variables of the lower limb as risk factors for the prevalence and severity of AT in athletes, especially in Caucasians, but there are few reports on African elite athletes. Because it is established that anthropometric and biomechanical values vary with racial disposition, this study was designed to investigate the association between selected physical and biomechanical variables of the lower limb and the prevalence and severity of AT in Nigerian elite track and field athletes. Read More

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http://dx.doi.org/10.4103/npmj.npmj_179_19DOI Listing

Achilles Tendinopathy: Pathophysiology, Epidemiology, Diagnosis, Treatment, Prevention, and Screening.

J Spec Oper Med 2020 ;20(1):125-140

Achilles tendinopathy (AT) is a clinical term describing a nonrupture injury of the Achilles tendon where the patient presents with pain, swelling, and reduced performance and symptoms exacerbated by physical activity. About 52% of runners experience AT in their lifetime and in the United States military the rate of clinically diagnosed AT cases was 5/1000 person-yr in 2015. The pathophysiology can be viewed on a continuum proceeding from reactive tendinopathy where tenocytes proliferate, protein production increases, and the tendon thickens; to tendon disrepair in which tenocytes and protein production increase further and there is focal collagen fiber disruption; to degenerative tendinopathy involving cell death, large areas of collagen disorganization, and areas filled with vessels and nerves. Read More

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Systematic Review of Photobiomodulation Therapy (PBMT) on the Experimental Calcaneal Tendon Injury in Rats.

Photochem Photobiol 2020 Mar 19. Epub 2020 Mar 19.

Post-graduation program in Biomedical Engineering, Universidade Brasil, Sao Paulo, Brazil.

This systematic review analyzed the light parameters and the effects of photobiomodulation therapy (PBMT) through low-level laser therapy (LLLT) and/or LED (light-emitting diode) on tendon repair of rats submitted to calcaneal injury. This study was conducted in accordance with the guidelines of the Preferred Reporting Items for Meta-Analysis, and PubMed and MEDLINE databases were accessed to search eligible studies published in English. The search terms were as follows: "Achilles tendon" or "Calcaneal tendon" or "tendon injuries" or "soft tissue injuries" and "tendinopathy" or "tendinitis" and "low-level light therapy" or "low-level laser therapy" or "low intensity power therapy" or "light-emitting diode" or photobiomodulation. Read More

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http://dx.doi.org/10.1111/php.13262DOI Listing

A Rare Presentation of Gout: Achilles Tendinopathy, Ultrasonographic Assessment.

Am J Med Sci 2020 04 23;359(4):245-246. Epub 2020 Jan 23.

Department of Physical Medicine and Rehabilitation Health Sciences University, Ankara Training and Research Hospital Ankara, Turkey.

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http://dx.doi.org/10.1016/j.amjms.2020.01.016DOI Listing

The shift in macrophages polarisation after tendon injury: A systematic review.

J Orthop Translat 2020 Mar 24;21:24-34. Epub 2019 Dec 24.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

Background: The role of macrophages (Mφs) in tendon injury healing is controversy. The aims of this study were to determine whether there is a shift in Mφs polarisation after an acute and chronic tendon injury ​and to assess whether the Mφs polarisation between the partial and complete rupture is different.

Methods: This systematic review of the scientific literature was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Cochrane guidelines. Read More

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http://dx.doi.org/10.1016/j.jot.2019.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013123PMC

Functional COL1A1 variants are associated with the risk of acute musculoskeletal soft tissue injuries.

J Orthop Res 2020 Feb 4. Epub 2020 Feb 4.

Division of Exercise Science and Sports Medicine, Department of Human Biology, Health Through Physical Activity, Lifestyle and Sport Research Centre, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Studies have reported the association of the COL1A1 Sp1 binding site variant (rs1800012) with the risk of acute musculoskeletal soft tissue injuries. Interaction with the COL1A1 promoter variant (rs1107946) has also been proposed to modulate acute injury risk. Conversely, neither of these loci have been associated with chronic musculoskeletal soft tissue phenotypes. Read More

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http://dx.doi.org/10.1002/jor.24621DOI Listing
February 2020

Spectrum of Tendon Pathologies: Triggers, Trails and End-State.

Int J Mol Sci 2020 Jan 28;21(3). Epub 2020 Jan 28.

Experimental Trauma Surgery, Department of Trauma Surgery, University Medical Center Regensburg, Am Biopark 9, 93053 Regensburg, Germany.

The biggest compartment of the musculoskeletal system is the tendons and ligaments. In particular, tendons are dense tissues connecting muscle to bone that are critical for the integrity, function and locomotion of this system. Due to the increasing age of our society and the overall rise in engagement in extreme and overuse sports, there is a growing prevalence of tendinopathies. Read More

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http://dx.doi.org/10.3390/ijms21030844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037288PMC
January 2020

Extracorporeal Shock Wave Therapy for Achilles Tendinopathy.

Biomed Res Int 2019 26;2019:3086910. Epub 2019 Dec 26.

Institute of Sport Sciences, The Jerzy Kukuczka Academy of Physical Education, Mikolowska 72A, 40-065 Katowice, Poland.

Extracorporeal shock wave therapy (ESWT) is among the conservative treatments for Achilles tendinopathy. Unfortunately, no optimal application parameters have been determined that would ensure ESWT effectiveness in this condition. The aim of the paper is to use research reports on ESWT in patients with Achilles tendinopathy to help practising physiotherapists establish the most effective intervention parameters. Read More

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http://dx.doi.org/10.1155/2019/3086910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948318PMC

Systemic inflammatory response to the Radial Pressure Wave Therapy (RPWT) in collagenase-induced Achilles tendinopathy treated with Adipose Derived Stem Cells or Platelet Rich Plasma.

Pol J Vet Sci 2019 Dec;22(4):735-742

Department of Surgery with Clinic, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, pl. Grunwaldzki 51, 50-366 Wrocław, Poland.

Novel tendinopathy treatment protocols should be assessed for safety. The goal of this work was to compare differences in selected systemic inflammatory marker concentrations after two treatment protocols for collagenase induced Achilles tendinopathy in sheep. 14 sheep (aged 5 and 6 years, Polish Mountain Sheep breed, weight 60-70kg) were injected with bacterial collagenase type 1A-S (Clostridium histolyticum, C-5894, Sigma Aldrich, Poznań, Poland) bilaterally to Achilles tendons. Read More

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http://dx.doi.org/10.24425/pjvs.2019.131403DOI Listing
December 2019

Influence of Radial Pressure Wave Therapy (RPWT) on collagenase-induced Achilles tendinopathy treated with Platelet Rich Plasma and Autologous Adipose Derived Stem Cells.

Pol J Vet Sci 2019 Dec;22(4):743-751

Department of Surgery with Clinic, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, pl. Grunwaldzki 51, 50-366 Wrocław, Poland.

Tendinopathy treatment poses a current challenge for sport medicine due to unique physiology and biomechanics of tendons. The goal of this work was to compare the efficacy of the addition of the radial pressure wave therapy (RPWT) treatment to injection of autologous Adipose Derived Stem Cells (ADSCs) or Platelet Rich Plasma (PRP) in the therapeutic procedure for collagenase induced Achilles tendinopathy in sheep. 14 sheep (aged 5 and 6 years, Polish Mountain Sheep breed, weight 60-70 kg) were injected bacterial collagenase type 1A-S (Clostridium histolyticum, C-5894, Sigma Aldrich, Poznań, Poland) bilaterally to Achilles tendons. Read More

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http://dx.doi.org/10.24425/pjvs.2019.131405DOI Listing
December 2019

Mechanical Demands at the Ankle Joint During Saut de Chat and Temps levé Jumps in Classically Trained Ballet Dancers.

Open Access J Sports Med 2019 6;10:191-197. Epub 2019 Dec 6.

Department of Health and Human Development, Western Washington University, Bellingham, WA, USA.

Background: During ballet, injuries to the Achilles tendon are associated with the take-off phase of various jumps.

Research Question: The purpose of the study was to assess differences in mechanical demand on the body, specifically at the ankle, in two single-leg jumps commonly trained in ballet: a saut de chat (SDC) and a temps levé (TL).

Methods: Fifteen classically trained female dancers had 16 reflective markers placed on the lower body and each dancer performed each jump three times on a force plate. Read More

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http://dx.doi.org/10.2147/OAJSM.S234289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902839PMC
December 2019

Gouty Achilles Tendinopathy: A Case Report.

J Am Podiatr Med Assoc 2019 Jul;109(4):327-333

Tendinopathy in the presence of gouty arthropathy is relatively common, yet the clinical suspicion for gout involvement in acute tendon pain remains low. A 49-year-old man presented with an acute, tender, erythematous mass to the right posterior heel. A computed tomographic scan was obtained, which revealed a septated fluid collection superficial to the Achilles tendon. Read More

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http://dx.doi.org/10.7547/18-129DOI Listing

Variability within the human iNOS gene and Achilles tendon injuries: Evidence for a heterozygous advantage effect.

J Sci Med Sport 2020 Apr 8;23(4):342-346. Epub 2019 Nov 8.

Centre for Sport, Exercise and Life Sciences, Coventry University, The University of Northampton, UK. Electronic address:

Objectives: The aim of this case control genetic association study was to explore whether two variants within the inducible nitric oxide synthase (iNOS) gene, rs2779249 (C/A) and rs2248814 (A/G), influenced the risk of Achilles tendinopathy in a British population.

Design: Candidate gene, case control association study.

Method: We recruited 145 individuals diagnosed with Achilles tendon pathology and 132 asymptomatic controls. Read More

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http://dx.doi.org/10.1016/j.jsams.2019.11.001DOI Listing

Inhibition of CD44 induces apoptosis, inflammation, and matrix metalloproteinase expression in tendinopathy.

J Biol Chem 2019 12 15;294(52):20177-20184. Epub 2019 Nov 15.

Department of Nursing, College of Nursing, Chung Hwa University of Medical Technology, Tainan, Taiwan

Apoptosis has emerged as a primary cause of tendinopathy. CD44 signaling pathways exert anti-apoptotic and -inflammatory effects on tumor cells, chondrocytes, and fibroblast-like synoviocytes. The aim of this study was to examine the association among CD44, apoptosis, and inflammation in tendinopathy. Read More

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http://dx.doi.org/10.1074/jbc.RA119.009675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937571PMC
December 2019

Controlled trial to compare the Achilles tendon load during running in flatfeet participants using a customized arch support orthoses vs an orthotic heel lift.

BMC Musculoskelet Disord 2019 Nov 13;20(1):535. Epub 2019 Nov 13.

Department of Orthopaedics and Traumatology, Faculty of Medicine, CUHK, Hong Kong, Hong Kong.

Background: Achilles tendinopathy is one of the most common overuse injuries in running, and forefoot pronation, seen in flatfeet participants, has been proposed to cause additional loading across the Achilles tendon. Foot orthoses are one of the common and effective conservative treatment prescribed for Achilles tendinopathy, it works by correcting the biomechanical malalignment and reducing tendon load. Previous studies have shown reduction of Achilles Tendon load (ATL) during running by using customized arch support orthosis (CASO) or an orthotic heel lift (HL). Read More

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http://dx.doi.org/10.1186/s12891-019-2898-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854722PMC
November 2019

Characterisation of Achilles tendon pain in recreational runners using multidimensional pain scales.

J Sci Med Sport 2020 Mar 30;23(3):258-263. Epub 2019 Oct 30.

Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town. South Africa. Electronic address:

Objectives: The main assessment tool for Achilles tendinopathy (AT) is the VISA-A. However, the VISA-A only assesses the physical impairments that result from tendon pain. This study sought to describe and assess tendon pain using other multidimensional pain scales; the short forms of the McGill pain questionnaire (sf-MPQ) and the Brief Pain Inventory (sf-BPI). Read More

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http://dx.doi.org/10.1016/j.jsams.2019.10.016DOI Listing

Treatment with Human Amniotic Suspension Allograft Improves Tendon Healing in a Rat Model of Collagenase-Induced Tendinopathy.

Cells 2019 11 8;8(11). Epub 2019 Nov 8.

Harvard Medical School, the Harvard Stem Cell Institute, and Department of Orthopedic Surgery, Brigham and Women's Hospital, 7 Divinity Avenue, Cambridge, MA 02138, USA.

Treatment of tendon injuries is challenging, with neither conservative nor surgical approaches providing full recovery. Placental-derived tissues represent a promising tool for the treatment of tendon injuries. In this study, human amniotic suspension allograft (ASA) was investigated in a pre-clinical model of Achilles tendinopathy. Read More

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http://dx.doi.org/10.3390/cells8111411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912389PMC
November 2019
3 Reads

The Apoptosis Pathway and CASP8 Variants Conferring Risk for Acute and Overuse Musculoskeletal Injuries.

J Orthop Res 2020 03 11;38(3):680-688. Epub 2019 Nov 11.

Department of Human Biology, Division of Exercise Science and Sports Medicine, Faculty of Health Sciences, University of Cape Town, Postal: No 1 Boundary Road, ESSM Level 3, SISSA Building Newlands, Cape Town, 7700, South Africa.

Rotator cuff tendinopathy (RCT), anterior cruciate ligament (ACL) ruptures, and carpal tunnel syndrome (CTS), are examples of chronic (RCT and CTS) and acute (ACL ruptures) musculoskeletal soft tissue injuries. These injuries are multifactorial in nature, with several identified intrinsic and extrinsic risk factors. Previous studies have implicated specific sequence variants within genes encoding structural and regulatory components of the extracellular matrix of tendons and/ligaments to predispose individuals to these injuries. Read More

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http://dx.doi.org/10.1002/jor.24504DOI Listing
March 2020
1 Read

Traumatic Double-Level Unilateral Achilles Tendon Rupture: A Case Report.

Am J Case Rep 2019 Oct 12;20:1500-1504. Epub 2019 Oct 12.

Department of Orthopedic Surgery, Bahrain Defense Force Royal Medical Service, Riffa, Bahrain.

BACKGROUND Unilateral double-level Achilles tendon tear is a rare presentation that has not been previously reported in the English literature. Diagnosis and management of these cases are challenging, and outcomes are not well described in the literature. CASE REPORT A 46-year-old man presented to us with ankle pain following a football sports injury. Read More

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http://dx.doi.org/10.12659/AJCR.917972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802605PMC
October 2019
1 Read

Intrinsic foot muscles morphological modifications in patients with Achilles tendinopathy: A novel case-control research study.

Phys Ther Sport 2019 Nov 3;40:208-212. Epub 2019 Oct 3.

Facultad de Enfermería, Físioterapia y Podologia. Universidad Complutense de Madrid, Madrid. Spain.

Objective: To compare the thickness and cross-sectional area (CSA) of the Abductor Hallucis Brevis (AHB), Flexor Digitorum Brevis (FDB) and Flexor Hallucis Brevis (FHB) in subjects with and without chronic mid-portion Achilles tendinopathy (AT).

Design: A case-control research study.

Setting: A private clinic. Read More

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http://dx.doi.org/10.1016/j.ptsp.2019.09.014DOI Listing
November 2019
1 Read

[Conservative Therapy of Achilles Tendinopathy in Sports Medicine].

Praxis (Bern 1994) 2019 Sep;108(13):851-858

ALTIUS Swiss Sportmed Center AG, Rheinfelden.

Conservative Therapy of Achilles Tendinopathy in Sports Medicine Due to its key role in power transmission, the Achilles tendon is a common site of acute and overuse injuries in running athletes. Therefore, a sports physician needs to know some anatomic, diagnostic and therapeutic key points to be able to establish an individualized therapy approach. With regard to the «in» and «out of season» period, there is a primary focus on physio- and shock-wave therapy. Read More

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http://dx.doi.org/10.1024/1661-8157/a003296DOI Listing
September 2019
4 Reads

HMGB1 mediates the development of tendinopathy due to mechanical overloading.

PLoS One 2019 27;14(9):e0222369. Epub 2019 Sep 27.

MechanoBiology Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

Mechanical overloading is a major cause of tendinopathy, but the underlying pathogenesis of tendinopathy is unclear. Here we report that high mobility group box1 (HMGB1) is released to the tendon extracellular matrix and initiates an inflammatory cascade in response to mechanical overloading in a mouse model. Moreover, administration of glycyrrhizin (GL), a naturally occurring triterpene and a specific inhibitor of HMGB1, inhibits the tendon's inflammatory reactions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222369PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764662PMC
March 2020
1 Read
3.234 Impact Factor

Cigarette smoking intensifies tendinopathy of the LHBT. A microscopic study after arthroscopic treatment.

Pol J Pathol 2019 ;70(2):134-138

Department of Clinical Pathomorphology, Ludwik Rydygier's Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.

Smoking has a damaging effect on the musculoskeletal system, which was presented by authors in the rotator cuff and Achilles tendons studies; however, there are a lack of data about the effect of smoking on disorders of the long head of the biceps tendon (LHBT), particularly at the microscopic level. The purpose of this study was to investigate the effect of the tobacco smoking on the histopathologic alterations of the LHBT. Thirty-six patients with preoperatively diagnosed tendinopathy of the LHBT were referred to the Orthopaedics Department. Read More

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http://dx.doi.org/10.5114/pjp.2019.87104DOI Listing
October 2019
1 Read

Reliability of a two-probe ultrasound imaging procedure to measure strain in the Achilles tendon.

J Foot Ankle Res 2019 18;12:49. Epub 2019 Sep 18.

1Department of Podiatry, School of Clinical Sciences, Faculty of Health & Environmental Sciences, Auckland University of Technology, Private Bag 92006, Auckland, 1142 New Zealand.

Background: Alteration in the strain properties of the Achilles tendon may lead to adaptations such as pathological stiffening. Stiff tendons have reduced adaptive ability, which may increase the risk for developing tendinopathy. Strain can be measured using musculoskeletal ultrasound imaging. Read More

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http://dx.doi.org/10.1186/s13047-019-0358-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751664PMC
May 2020
1 Read

Central Tendon-Splitting Approach and Double Row Suturing for the Treatment of Insertional Achilles Tendinopathy.

Biomed Res Int 2019 21;2019:4920647. Epub 2019 Aug 21.

Departments of Joint Surgery and Orthopedic Trauma, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong, China.

Background: To assess the clinical outcomes of central tendon-splitting approach and double row anchor suturing for the treatment of insertional Achilles tendinopathy.

Methods: 28 patients (28 feet) diagnosed with insertional Achilles tendinopathy were included in this study. The inclusions were symptom of hindfoot pain around the insertion of the Achilles tendon, radiographic demonstration of calcification, or degeneration of the Achilles tendon, showing no symptom improvement even after standard nonsurgical treatment for more than six months. Read More

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http://dx.doi.org/10.1155/2019/4920647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720369PMC
February 2020
4 Reads

Education and exercise supplemented by a pain-guided hopping intervention for male recreational runners with midportion Achilles tendinopathy: A single cohort feasibility study.

Phys Ther Sport 2019 Nov 14;40:107-116. Epub 2019 Aug 14.

Sports and Exercise Medicine. Queen Mary University of London, London, UK; Department of Physiotherapy, Monash University, Australia. Electronic address:

Objectives: To examine the feasibility of recommended education and exercise supplemented by a hopping intervention implemented based on self-reported pain over 12 weeks for recreational runners with Achilles tendinopathy.

Design: Single cohort feasibility study.

Setting: One private physiotherapy clinic in Melbourne, Australia. Read More

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http://dx.doi.org/10.1016/j.ptsp.2019.08.007DOI Listing
November 2019

In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy.

J Orthop Res 2020 01 13;38(1):59-69. Epub 2019 Sep 13.

Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia.

The deposition of aggrecan/hyaluronan (HA)-rich matrix within the tendon body and surrounding peritenon impede tendon healing and result in compromised biomechanical properties. Hence, the development of novel strategies to achieve targeted removal of the aggrecan-HA pericellular matrix may be effective in treating tendinopathy. The current study examined the therapeutic potential of a recombinant human hyaluronidase, rHuPH20 (FDA approved for reducing HA accumulation in tumors) for treating murine Achilles tendinopathy. Read More

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http://dx.doi.org/10.1002/jor.24459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917826PMC
January 2020
3 Reads
2.986 Impact Factor

Updates in Tendinopathy Treatment Options.

Clin Podiatr Med Surg 2019 Oct 18;36(4):543-552. Epub 2019 Jul 18.

California College of Podiatric Medicine, Samuel Merritt University, 3100 Telegraph Ave, Oakland, CA 94609, USA.

Tendinopathy is a common but disabling condition. The term describes a complex, multifaceted pathology of the tendon characterized by pain, decreased function, and reduced exercise tolerance. Tendinopathy accounts for up to 30% of general practice musculoskeletal consultations. Read More

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http://dx.doi.org/10.1016/j.cpm.2019.06.002DOI Listing
October 2019
2 Reads

The current role of Astym therapy in the treatment of musculoskeletal disorders.

Postgrad Med 2020 Jan 28;132(1):66-71. Epub 2019 Aug 28.

Department of Physical Medicine and Rehabilitation, "Cruz Roja San Jose and Santa Adela" University Hospital, Madrid, Spain.

: In general, chronic problems of soft tissues (muscles, tendons, ligaments) are due to scarring or degeneration. Astym therapy (Performance Dynamics, Inc. Muncie, Indiana) has been reported to address tendinopathy by stimulating regeneration in soft tissues (muscles, tendons, ligaments) and the resorption of unwanted scar tissue that causes pain and limits mobility. Read More

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http://dx.doi.org/10.1080/00325481.2019.1654836DOI Listing
January 2020
3 Reads

Flexor Hallucis Longus Transfer Improves Achilles Tendon Load to Failure in Surgery for Non-Insertional Tendinopathy: A Biomechanical Study.

J Bone Joint Surg Am 2019 Aug;101(16):1505-1512

University of Connecticut Health Center, Farmington, Connecticut.

Background: Non-insertional Achilles tendinopathy is a common disorder that may be treated with surgical debridement. A flexor hallucis longus (FHL) transfer is recommended if debridement of ≥50% is performed; however, there are no biomechanical data to support this. The purpose of this study was to assess the added biomechanical strength provided by an FHL transfer with incrementally sized non-insertional Achilles tendon defects. Read More

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http://dx.doi.org/10.2106/JBJS.18.01338DOI Listing
August 2019
1 Read

Current trends in tendinopathy management.

Best Pract Res Clin Rheumatol 2019 02 8;33(1):122-140. Epub 2019 Mar 8.

La Trobe University Sport and Exercise Medicine Research Centre, La Trobe University, Corner of Plenty Road and Kingsbury Drive, Bundoora, Victoria, 3083, Australia. Electronic address:

Tendinopathy (pain and dysfunction in a tendon) is a prevalent clinical musculoskeletal presentation across the age spectrum, mostly in active and sporting people. Excess load above the tendon's usual capacity is the primary cause of clinical presentation. The propensity towards chronicity and the extended times for recovery and optimal function and the challenge of managing tendinopathy in a sporting competition season make this a difficult condition to treat. Read More

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http://dx.doi.org/10.1016/j.berh.2019.02.001DOI Listing
February 2019
6 Reads

Altered Strength Profile in Achilles Tendinopathy: A Systematic Review and Meta-Analysis.

J Athl Train 2019 Aug 6;54(8):889-900. Epub 2019 Aug 6.

Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar.

Background: Persistent strength deficits secondary to Achilles tendinopathy (AT) have been postulated to account for difficulty engaging in tendon-loading movements, such as running and jumping, and may contribute to the increased risk of recurrence. To date, little consensus exists on the presence of strength deficits in AT. Consequently, researchers are uncertain about the appropriate methods of assessment that may inform rehabilitation in clinical practice. Read More

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http://dx.doi.org/10.4085/1062-6050-43-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761911PMC
August 2019
2 Reads

Significance of Asymptomatic Tendon Pathology in Athletes.

Curr Sports Med Rep 2019 Jun;18(6):192-200

McGaw Medical Center of Northwestern University/Shirley Ryan AbilityLab, Chicago, IL.

Symptomatic tendinopathy can be a disabling condition for athletes. Common sites of tendinopathy in athletes include the rotator cuff (RTC), Achilles, and patellar tendons. Advanced imaging modalities, such as magnetic resonance imaging and ultrasound occasionally identify tendinopathic changes in asymptomatic individuals. Read More

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http://Insights.ovid.com/crossref?an=00149619-201906000-0000
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http://dx.doi.org/10.1249/JSR.0000000000000600DOI Listing
June 2019
3 Reads

Updates in the Management of Acute and Chronic Lesions of the Achilles Tendon.

Authors:
Phinit Phisitkul

Foot Ankle Clin 2019 Sep 18;24(3):xv-xvi. Epub 2019 Jun 18.

Tri-State Specialists, LLP 2730 Pierce Street, Suite 300, Sioux City, IA 51104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fcl.2019.05.003DOI Listing
September 2019

Surgical Strategies for the Treatment of Insertional Achilles Tendinopathy.

Foot Ankle Clin 2019 Sep 18;24(3):533-559. Epub 2019 Jun 18.

Department of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT 84108, USA.

Insertional Achilles tendinopathy is one of the most common Achilles tendon disorders and often results in substantial heel pain and functional disability. There is consensus that treatment of insertional Achilles tendinopathy should start with nonoperative modalities. Surgery should be reserved for patients who fail exhaustive conservative treatment for a period of 3 months to 6 months and include débridement of insertional calcifications. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.005DOI Listing
September 2019
7 Reads

Minimally Invasive and Endoscopic Treatment of Haglund Syndrome.

Foot Ankle Clin 2019 Sep 18;24(3):515-531. Epub 2019 May 18.

Department of Orthopaedics and Traumatology, North District Hospital, 9 Po Kin Road, Sheung Shui, NT, Hong Kong SAR 999077, China.

Haglund syndrome is a triad of posterosuperior calcaneal prominence (Haglund deformity), retrocalcaneal bursitis, and insertional Achilles tendinopathy. The sources of pain include the posterior calcaneal wall cartilage, retrocalcaneal and subcutaneous adventitial bursa, and the Achilles tendon. Resection of the posterosuperior calcaneal tubercle, bursectomy, excision of the Achilles tendon pathology, reattachment of the Achilles tendon, gastrocnemius aponeurotic recession, and flexor hallucis longus transfer have been proposed as surgical treatment options. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10837515193004
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http://dx.doi.org/10.1016/j.fcl.2019.04.006DOI Listing
September 2019
8 Reads

Nonsurgical Treatment Options for Insertional Achilles Tendinopathy.

Foot Ankle Clin 2019 Sep 22;24(3):505-513. Epub 2019 May 22.

Department of Physical Therapy and Rehabilitation Science, University of Iowa, 500 Newton Road, 1-252 Medical Education Building, Iowa City, IA 52242, USA. Electronic address:

Most nonoperative treatments for insertional Achilles tendinopathy (IAT) have insufficient evidence to support treatment recommendations. Exercise has the highest level of evidence supporting the ability of this treatment option to reduce IAT pain. The effects of exercise may be enhanced by a wide variety of other treatments, including soft tissue treatment, nutritional supplements, iontophoresis, education, stretching, and heel lifts. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216975PMC
September 2019
2 Reads

Minimally Invasive and Endoscopic Approach for the Treatment of Noninsertional Achilles Tendinopathy.

Foot Ankle Clin 2019 Sep 21;24(3):495-504. Epub 2019 May 21.

Tri-State Specialists, LLP, 2730 Pierce Street Suite 300, Sioux City, IA 51104, USA.

Minimally invasive treatment can offer an earlier recovery with less pain and scarring compared with traditional open surgeries. The goals of minimally invasive surgery are to debride degenerative tendon, stimulate healing, and, when appropriate, repair damaged tendon. Sclerotherapy and prolotherapy have been shown to reduce neovascularization and pain. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.007DOI Listing
September 2019
3 Reads

Biologics in the Treatment of Achilles Tendon Pathologies.

Foot Ankle Clin 2019 Sep 21;24(3):471-493. Epub 2019 May 21.

Humanitas San Pio X, via Francesco Nava, 31, 20159 Milano, Lombardia, Italy.

Regenerative medicine is gaining more and more space for the treatment of Achilles pathologic conditions. Biologics could play a role in the management of midportion Achilles tendinopathy as a step between conservative and surgical treatment or as an augmentation. Higher-level studies are needed before determining a level of treatment recommendation for biologic strategies for insertional Achilles tendinopathy. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.009DOI Listing
September 2019

Maximizing Return to Sports After Achilles Tendon Rupture in Athletes.

Foot Ankle Clin 2019 Sep 18;24(3):439-445. Epub 2019 May 18.

Department of Orthopedic Surgery, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, 622 West 168th Street, PH11-Center Wing, New York, NY 10032, USA. Electronic address:

Achilles tendon ruptures are devastating injuries to athletes, with return-to-sports rates around 70% and some risk for diminished performance post-injury. Surgical management in athletes is often favored for a number of reasons, although evidence guiding the optimal treatment is limited. Functional rehabilitation has been supported as a key component of operative and nonoperative treatment plans. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.003DOI Listing
September 2019
3 Reads

Anatomical and Functional Considerations in Achilles Tendon Lesions.

Foot Ankle Clin 2019 Sep;24(3):371-385

Department of Orthopaedic Surgery, University of North Carolina, 130 Mason Farm Rd, Chapel Hill, NC 27599, USA. Electronic address:

The pathologic conditions of the Achilles tendon are best understood in the context of its unique anatomy and functional demands. Some of these unique considerations include its high physiologic load demands, microscopic tissue composition, muscular origin spanning the knee joint, intimate insertional relationship with the plantar fascia, sensory innervation, and vascular supply with watershed areas. Risks of both acute rupture and chronic tendinopathy are affected by the tendon's anatomy and its functional demands. Read More

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http://dx.doi.org/10.1016/j.fcl.2019.04.001DOI Listing
September 2019
3 Reads

Biomechanical alterations in individuals with Achilles tendinopathy during running and hopping: A systematic review with meta-analysis.

Gait Posture 2019 09 12;73:189-201. Epub 2019 Jul 12.

Sports and Exercise Medicine. Queen Mary University of London, United Kingdom; Physiotherapy Department, Barts Health NHS Trust, London, United Kingdom. Electronic address:

Introduction: Biomechanical alterations during running and hopping in people with Achilles tendinopathy (AT) may provide treatment and prevention targets. This review identifies and synthesises research evaluating biomechanical alterations among people with AT during running, jumping and hopping.

Method: MEDLINE, EMBASE, CiNAHL and SPORTDiscus were searched in July 2018 for case control, cross-sectional and prospective studies investigating kinematics, kinetics, plantar pressures and neuromuscular activity in AT participants during running or hopping. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183179
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http://dx.doi.org/10.1016/j.gaitpost.2019.07.121DOI Listing
September 2019
4 Reads

[Experimental study of platelet-rich plasma in treatment of Achilles tendinopathy in rabbits].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Jul;33(7):871-876

Department of Orthopedics, the 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou Gansu, 730050,

Objective: To explore the effect of platelet-rich plasma (PRP) in treatment of Achilles tendinopathy in rabbits, and provide experimental evidence for the clinical application of PRP in treatment of Achilles tendinopathy.

Methods: Forty-eight adult New Zealand white rabbits, weighing 2.5-3. Read More

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http://dx.doi.org/10.7507/1002-1892.201809045DOI Listing
July 2019
5 Reads

Fluoroquinolones and the risk of tendon injury: a systematic review and meta-analysis.

Eur J Clin Pharmacol 2019 Oct 4;75(10):1431-1443. Epub 2019 Jul 4.

Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal.

Purpose: Tendinopathy is a known adverse reaction associated to fluoroquinolones, but a meta-analysis was not yet published. The aim of this study was to conduct a systematic review and a meta-analysis of the scientific evidence evaluating the risk of tendon injury associated with fluoroquinolones.

Methods: A literature search was conducted to identify observational studies which reported results on the risk of Achilles tendon rupture (ATR), risk of Achilles tendinitis (AT), or risk of any tendon disorders (ATD). Read More

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http://dx.doi.org/10.1007/s00228-019-02713-1DOI Listing
October 2019
3 Reads

Prevalence and factors associated with asymptomatic Achilles tendon pathology in male distance runners.

Phys Ther Sport 2019 Sep 17;39:64-68. Epub 2019 Jun 17.

Deakin University, Centre for Sport Research, School of Exercise and Nutrition Sciences, Melbourne, Australia; Auckland University of Technology, Sport Performance Research Institute New Zealand, Auckland, New Zealand. Electronic address:

Objectives: This study investigated the prevalence of tendon pathology and associated factors in experienced, high mileage male endurance runners with no history of Achilles tendon pain.

Design: Cross-sectional study.

Setting: Achilles tendinopathy is a debilitating running injury affecting 50% of distance runners over their lifetime. Read More

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http://dx.doi.org/10.1016/j.ptsp.2019.06.006DOI Listing
September 2019
5 Reads

Pressure changes in the Kager fat pad at the extremes of ankle motion suggest a potential role in Achilles tendinopathy.

Knee Surg Sports Traumatol Arthrosc 2020 Jan 29;28(1):148-154. Epub 2019 Jun 29.

Fortius Clinic, London, UK.

Introduction: The Kager fat pad is one of the largest soft tissue structures local to the ankle joint, yet it is poorly understood. It has been hypothesised to have a role in Achilles tendinopathy. This study aimed to investigate the pressure areas in the Kager fat pad adjacent to the Achilles tendon and to assess the anatomy and deformation of the Kager fat pad in cadavers. Read More

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http://dx.doi.org/10.1007/s00167-019-05585-1DOI Listing
January 2020
5 Reads