90,150 results match your criteria Accounting And Finance[Journal]


The Association of Non-Alcoholic Fatty Liver Disease and Cardiac Structure and Function - Framingham Heart Study.

Liver Int 2020 Jul 11. Epub 2020 Jul 11.

Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Boston, MA, United States.

Background & Aims: Non-alcoholic fatty liver disease confers increased risk for cardiovascular disease, including heart failure, for reasons that remain unclear. Possible pathways could involve an association of liver fat with cardiac structural or functional abnormalities even after accounting for body size.

Methods: We analyzed N=2,356 Framingham Heart Study participants (age 52±12 years, 52% women) who underwent echocardiography and standardized computed tomography (CT) measures of liver fat. Read More

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http://dx.doi.org/10.1111/liv.14600DOI Listing

Budget impact analysis of the use of oral and intravenous therapy regimens for the treatment of relapsed or refractory multiple myeloma in Germany.

Eur J Health Econ 2020 Jul 11. Epub 2020 Jul 11.

Health Economics, WifOR, Darmstadt, Germany.

Background: In Germany, several triplet therapies for treating relapsed or refractory multiple myeloma (rrMM) patients have recently been approved. While most of them are administered intravenously, ixazomib-based combination is the only orally bioavailable regimen.

Objective: To conduct a 1-year and 3-year budget impact analysis (BIA) of different novel triplets to treat patients with rrMM in second or subsequent therapy lines accounting for costs covered by German statutory health insurance (SHI). Read More

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http://dx.doi.org/10.1007/s10198-020-01219-3DOI Listing

Clinical Features and Prognosis of Merkel Cell Carcinoma in Elderly Patients.

Med Sci Monit 2020 Jul 12;26:e924570. Epub 2020 Jul 12.

Department of Plastic Surgery, Anhui Medical University, Hefei, Anhui, China (mainland).

BACKGROUND Merkel cell carcinoma (MCC) occurs primarily among elderly patients over 70 years old, but the ability to predict the prognosis of these elderly patients is poor. This population-based study aimed to identify prognostic risk factors for elderly patients with MCC. MATERIAL AND METHODS The survival and disease information of MCC patients age 65 years or older was downloaded from the SEER database, and all data were split into 2 groups based on age 80 years, with overall survival and MCC-specific survival as the main outcome indicators. Read More

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http://dx.doi.org/10.12659/MSM.924570DOI Listing

Development and validation of the Barriers to Physical Activity and Sport Questionnaire for lesbian, gay, bisexual, transgender and queer/questioning persons.

Public Health 2020 Jul 9;185:202-208. Epub 2020 Jul 9.

Departament d'Educació Física i Esportiva, Facultat de Ciències de l'Activitat Física i l'Esport, Universitat de València, Valencia, 46010 Spain. Electronic address:

Objective: The objective of the study was to develop the Barriers to Physical Activity and Sport Questionnaire for lesbian, gay, bisexual, transgender and queer/questioning (BPASQ-LGBTQ+ [encompassing all spectrums of sexuality and gender]) persons (BPASQ-LGBT), which measures barriers using a socio-ecological model, and to validate it through exploratory and confirmatory factor analysis.

Study Design: Validation study.

Methods: First, content validity was achieved by (a) developing a bank of items, (b) discussing the adequacy of the items in a committee of experts and classifying the selected ones under three socio-ecological levels (intrapersonal, interpersonal, environmental) and (c) refining wording and relevance of the items after a pilot test. Read More

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http://dx.doi.org/10.1016/j.puhe.2020.05.020DOI Listing

Heterogeneity in Temporal Ordering of Depression and Participation After Traumatic Brain Injury.

Arch Phys Med Rehabil 2020 Jul 9. Epub 2020 Jul 9.

Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle WA.

Objectives: To examine heterogeneity in the temporal patterns of depression and participation over the first two years post-TBI.

Design: Observational prospective longitudinal study.

Setting: Inpatient rehabilitation centers, with 1- and 2-year follow-up conducted primarily by telephone. Read More

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http://dx.doi.org/10.1016/j.apmr.2020.05.026DOI Listing

Prevalence and association of Panton-Valentine Leukocidin gene with the risk of sepsis in patients infected with Methicillin Resistant Staphylococcus aureus.

J Infect Public Health 2020 Jul 8. Epub 2020 Jul 8.

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; Hospital Universiti Sains Malaysia, Health Campus, USM, 16150 Kubang Kerian, Kelantan, Malaysia. Electronic address:

Background: Panton-Valentine Leukocidin (PVL), is one of the virulence gene expressed by Methicillin Resistant Staphylococcus aureus (MRSA) and is known to be associated with severe form of community acquired MRSA infection. The aim of this study is to investigate its prevalence in our setting and patient's clinical outcome.

Methods: A cross sectional study involve retrospective record review were done involving 90 MRSA positive isolates between November 2016 and October 2017. Read More

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http://dx.doi.org/10.1016/j.jiph.2020.06.018DOI Listing

Severity of Intervertebral Disc Herniation Regulates Cytokine and Chemokine Levels In Patients with Chronic Radicular Back Pain.

Osteoarthritis Cartilage 2020 Jul 9. Epub 2020 Jul 9.

Department of Orthopedic Surgery, Columbia University, New York, NY; Department of Biomedical Engineering, Columbia University, New York, NY. Electronic address:

Objective: The contributions of intervertebral disc disease and subject-specific covariates to systemic inflammation in low back pain are unknown. We examined the effects of symptomatic disc herniation (DH) and MRI herniation severity on serum cytokine levels in clinical subjects.

Design: Cytokine levels from lumbar DH subjects (N=78) were compared to control subjects (N=57) accounting for effects of DH, age, BMI and gender. Read More

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http://dx.doi.org/10.1016/j.joca.2020.06.009DOI Listing

Pollution sources of atmospheric fine particles and secondary aerosol characteristics in Beijing.

J Environ Sci (China) 2020 Sep 16;95:91-98. Epub 2020 Apr 16.

School of Municipal and Environmental Engineering, Co-Innovation Center for Green Building of Shandong Province, Shandong Jianzhu University, Jinan 250101, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3), Department of Environmental Science and Engineering, Fudan University, Shanghai 200438, China. Electronic address:

To investigate the secondary formation and pollution sources of atmospheric particles in urban Beijing, PM and its chemical components were collected and determined by URG-9000D ambient ion monitor (AIM) from March 2016 to January 2017. Among water-soluble ions (WSIs), NO, SO and NH (SNA) had the largest proportion (77.8%) with the total concentration of 23. Read More

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http://dx.doi.org/10.1016/j.jes.2020.04.002DOI Listing
September 2020

Emission patterns of biogenic volatile organic compounds from dominant forest species in Beijing, China.

J Environ Sci (China) 2020 Sep 15;95:73-81. Epub 2020 Apr 15.

College of Environmental Science and Engineering, Beijing Forestry University, Beijing 100083, China. Electronic address:

Biogenic volatile organic compounds (BVOCs) have significant effects on atmospheric chemistry, ozone formation and secondary organic aerosol formation. Considering few investigations about BOVCs emissions in north China where is facing serious air pollution in recent years, emissions of various BVOCs from 24 dominant forest species in Beijing were measured from June to September in 2018, using a dynamic headspace sampling method. More than one hundred BVOCs in the collected samples were identified by using an automatic thermal desorption-gas chromatography/mass spectrometry, and their emission rates based on leaf biomass were calculated. Read More

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http://dx.doi.org/10.1016/j.jes.2020.03.049DOI Listing
September 2020

Cause of PM pollution during the 2016-2017 heating season in Beijing, Tianjin, and Langfang, China.

J Environ Sci (China) 2020 Sep 7;95:201-209. Epub 2020 May 7.

Chinese Research Academy of Environmental Sciences, Beijing 100012, China.

To investigate the cause of fine particulate matter (particles with an aerodynamic diameter less than 2.5 µm, PM) pollution in the heating season in the North China Plain (specifically Beijing, Tianjin, and Langfang), water-soluble ions and carbonaceous components in PM were simultaneously measured by online instruments with 1-hr resolution, from November 15, 2016 to March 15, 2017. The results showed extreme severity of PM pollution on a regional scale. Read More

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http://dx.doi.org/10.1016/j.jes.2020.03.024DOI Listing
September 2020

Characteristics and ozone formation potential of volatile organic compounds in emissions from a typical Chinese coking plant.

J Environ Sci (China) 2020 Sep 4;95:183-189. Epub 2020 May 4.

State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.

Coking industry is an important volatile organic compounds (VOCs) emission source in China, however, detailed information on VOCs emissions is lacking. Therefore, we selected a typical mechanized coking plant and collected air samples according to the Emission Standard of Pollutants for Coking Chemical Industry (GB16171-2012). Using gas chromatography-mass spectrometry method, we analyzed the VOCs in the air samples, and applied maximum increment reactivity (MIR) rule to estimate ozone formation potential (OFP) of the VOCs emitted from the coke production. Read More

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http://dx.doi.org/10.1016/j.jes.2020.03.018DOI Listing
September 2020

Meningococcal carriage 7 years after introduction of a serogroup A meningococcal conjugate vaccine in Burkina Faso: results from four cross-sectional carriage surveys.

Lancet Infect Dis 2020 Jul 9. Epub 2020 Jul 9.

Norwegian Institute of Public Health, Skøyen, Oslo, Norway.

Background: In the first 2 years after a nationwide mass vaccination campaign of 1-29-year-olds with a meningococcal serogroup A conjugate vaccine (MenAfriVac) in Burkina Faso, carriage and disease due to serogroup A Neisseria meningitidis were nearly eliminated. We aimed to assess the long-term effect of MenAfriVac vaccination on meningococcal carriage and herd immunity.

Methods: We did four cross-sectional studies of meningococcal carriage in people aged 9 months to 36 years in two districts of Burkina Faso between May 2, 2016, and Nov 6, 2017. Read More

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http://dx.doi.org/10.1016/S1473-3099(20)30239-5DOI Listing

Temporal contiguity and ageing: The role of memory organization in cognitive decline.

J Neuropsychol 2020 Jul 11. Epub 2020 Jul 11.

Faculty of Psychology, Liverpool John Moores University, Liverpool, UK.

The temporal contiguity effect is the tendency to form associations between items presented in nearby study positions. In the present study, we explored whether temporal contiguity predicted conversion to cognitively unimpaired-declining (CUD) status from a baseline of unimpaired older adults. Data from 419 participants were drawn from the Wisconsin Registry of Alzheimer's Prevention (WRAP) data set and analysed with binary logistic regressions. Read More

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http://dx.doi.org/10.1111/jnp.12219DOI Listing

From one-side to two-sides: the effects of stomatal distribution on photosynthesis.

New Phytol 2020 Jul 11. Epub 2020 Jul 11.

Research Group on Plant Biology under Mediterranean Conditions, Universitat de les Illes Balears / Instituto de Investigaciones Agroambientales y de Economía del Agua (INAGEA), Carretera de Valldemossa Km 7.5, 07121, Palma de Mallorca, Illes Balears, Spain.

The functions of stomata have been studied for a long time, however, a clear understanding of the influences of stomatal distribution on photosynthesis, especially the CO diffusion, is still unclear. Here, we investigated the stomatal morphology, distribution on leaf surfaces, vein traits and gas exchange parameters of 61 species of which 29 were amphistomatous, spanning in 32 families. Photosynthesis (A) was tightly coupled with operational stomatal conductance (g ) and mesophyll conductance (g ) whether or not accounting for phylogenetic relationships. Read More

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http://dx.doi.org/10.1111/nph.16801DOI Listing

Antithrombotic medication and endovascular interventions associated with short-term exposure to particulate air pollution: A nationwide case-crossover study.

Environ Pollut 2020 Jul 4;266(Pt 1):115130. Epub 2020 Jul 4.

Centre for Environment and Health - Department of Public Health and Primary Care, KU Leuven, Herestraat 49, 3000 Leuven, Belgium; Epidemiology and Health Policy, Department of Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium. Electronic address:

Short-term exposure to air pollution has pro-thrombotic effects and triggers thrombo-embolic events such as myocardial infarction or stroke in adults. This study evaluates the association between short-term variation in air pollution and treatments for acute thrombo-embolic events among the whole Belgian population. In a bidirectional time-stratified case-crossover design, we included 227,861 events treated with endovascular intervention and 74,942 with antithrombotic enzymes that were reimbursed by the Belgian Social Security between January 1st, 2009 and December 31st, 2013. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.115130DOI Listing

A Practical Perspective on the Concordance Index for the Evaluation and Selection of Prognostic Time-to-Event Models.

J Biomed Inform 2020 Jul 8:103496. Epub 2020 Jul 8.

Department of Information Engineering, University of Padova, Padova, Italy. Electronic address:

Developing a prognostic model for biomedical applications typically requires mapping an individual's set of covariates to a measure of the risk that he or she may experience the event to be predicted. Many scenarios, however, especially those involving adverse pathological outcomes, are better described by explicitly accounting for the timing of these events, as well as their probability. As a result, in these cases, traditional classification or ranking metrics may be inadequate to inform model evaluation or selection. Read More

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http://dx.doi.org/10.1016/j.jbi.2020.103496DOI Listing

Risk factors for assaultive reinjury and death following a nonfatal firearm assault injury: A population-based retrospective cohort study.

Prev Med 2020 Jul 8:106198. Epub 2020 Jul 8.

Violence Prevention Research Program, Department of Emergency Medicine, University of California Davis School of Medicine, United States of America; University of California Firearm Violence Research Center, United States of America.

Individuals with a firearm injury are at high risk of subsequent firearm victimization, but characteristics associated with sustaining recurrent firearm injuries are not well understood. In this retrospective cohort study, we sought to quantify the hazards of sustaining subsequent assaultive firearm injuries among people with an initial firearm assault injury and to identify characteristics associated with recurrent victimization. Using hospital discharge, emergency department, and mortality records, we identified and followed all individuals aged ≥15 years with a nonfatal firearm assault injury resulting in an emergency department visit or hospital admission in California, 2005-2013. Read More

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http://dx.doi.org/10.1016/j.ypmed.2020.106198DOI Listing

How China is fostering sustainable growth: the interplay of green investment and production-based emission.

Environ Sci Pollut Res Int 2020 Jul 10. Epub 2020 Jul 10.

Department of Accounting and Information, Ling Tung University, Taichung City, Taiwan.

To mitigate environmental problems and to achieve sustainability, China is striving to transition to low-carbon urban economies. Among several significant steps, the country has made remarkable success in controlling the emissions from transportation, buildings, and energy by shutting down or relocating several polluting industries. This study contributes to the issue of sustainable growth debate using time series data from China for the period 1998-2017 and empirically examines the effects of green investment and renewable energy consumption on production-based carbon emissions for China. Read More

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http://dx.doi.org/10.1007/s11356-020-09933-4DOI Listing

Role of nebulized epinephrine in moderate bronchiolitis: a quasi-randomized trial.

Ir J Med Sci 2020 Jul 10. Epub 2020 Jul 10.

Department of Paediatric Medicine, University Hospital Kerry, Tralee, Ireland.

Background/aims: Bronchiolitis is the most common lower respiratory illness that characteristically affects the children below 2 years of age accounting about 2-3% of patients admitted to hospital each year [1-4]. We compared the effect of racemic epinephrine (RE) and 3% hypertonic saline (HS) nebulization on the length of stay (LOS) in the hospital.

Methods: We looked at the infants with moderate bronchiolitis, from October 2013 to March 2014. Read More

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http://dx.doi.org/10.1007/s11845-020-02293-5DOI Listing

Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy.

Commun Biol 2020 Jul 10;3(1):372. Epub 2020 Jul 10.

Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo, 162-8480, Japan.

Raman imaging has become an attractive technology in molecular biology because of its ability to detect multiple molecular components simultaneously without labeling. Two major limitations in accurately accounting for spectral features, viz., background removal and spectral unmixing, have been overcome by employing a modified and effective routine in multivariate curve resolution (MCR). Read More

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http://dx.doi.org/10.1038/s42003-020-1100-4DOI Listing

BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia.

J Parkinsons Dis 2020 Jul 8. Epub 2020 Jul 8.

Department of Biomedical Sciences, Cagliari University, Cagliari, Italy.

Background: We recently showed that striatal overexpression of brain derived neurotrophic factor (BDNF) by adeno-associated viral (AAV) vector exacerbated L-DOPA-induced dyskinesia (LID) in 6-OHDA-lesioned rats. An extensive sprouting of striatal serotonergic terminals accompanied this effect, accounting for the increased susceptibility to LID.

Objective: We set to investigate whether the BDNF effect was restricted to LID, or extended to dyskinesia induced by direct D1 receptor agonists. Read More

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http://dx.doi.org/10.3233/JPD-202061DOI Listing

River basin salinization as a form of aridity.

Proc Natl Acad Sci U S A 2020 Jul 10. Epub 2020 Jul 10.

Masdar Institute, Khalifa University of Science and Technology, PO Box 54224, Abu Dhabi, United Arab Emirates;

Soil-salinization affects, to a different extent, more than one-third of terrestrial river basins (estimate based on the Food and Agriculture Organization Harmonized World Soil Database, 2012). Among these, many are endorheic and ephemeral systems already encompassing different degrees of aridity, land degradation, and vulnerability to climate change. The primary effect of salinization is to limit plant water uptake and evapotranspiration, thereby reducing available soil moisture and impairing soil fertility. Read More

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http://dx.doi.org/10.1073/pnas.2005925117DOI Listing

The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure.

Authors:
Rodrigo Barquera Diana Iraíz Hernández-Zaragoza Alicia Bravo-Acevedo Esteban Arrieta-Bolaños Stephen Clayton Víctor Acuña-Alonzo Julio César Martínez-Álvarez Concepción López-Gil Carmen Adalid-Sáinz María Del Rosario Vega-Martínez Araceli Escobedo-Ruíz Eva Dolores Juárez-Cortés Alexander Immel Hanna Pacheco-Ubaldo Liliana González-Medina Abraham Lona-Sánchez Julio Lara-Riegos María Guadalupe de Jesús Sánchez-Fernández Rosario Díaz-López Gregorio Ulises Guizar-López Carolina Elizabeth Medina-Escobedo María Araceli Arrazola-García Gustavo Daniel Montiel-Hernández Ofelia Hernández-Hernández Flor Del Rocío Ramos-de la Cruz Francisco Juárez-Nicolás Jorge Arturo Pantoja-Torres Tirzo Jesús Rodríguez-Munguía Vicencio Juárez-Barreto Héctor Delgado-Aguirre Ariadna Berenice Escutia-González Isis Goné-Vázquez Gamaliel Benítez-Arvizu Francia Paulina Arellano-Prado Víctor Eduardo García-Arias Marla Estefanía Rodríguez-López Patricia Méndez-Mani Raquel García-Álvarez Marisela Del Rocío González-Martínez Guadalupe Aquino-Rubio Néstor Escareño-Montiel Tannya Verónica Vázquez-Castillo María Guadalupe Uribe-Duarte María de Jesús Ruíz-Corral Andrea Ortega-Yáñez Natalia Bernal-Felipe Benjamín Gómez-Navarro Agustín Jericó Arriaga-Perea Virginia Martínez-Bezies Rosa María Macías-Medrano Jesús Abraham Aguilar-Campos Raúl Solís-Martínez Ricardo Serrano-Osuna Mario J Sandoval-Sandoval Yolanda Jaramillo-Rodríguez Antonio Salgado-Adame Federico Juárez-de la Cruz Bárbara Novelo-Garza María de Los Ángeles Pavón-Vargas Norma Salgado-Galicia Maria Cátira Bortolini Carla Gallo Gabriel Bedoya Francisco Rothhammer Rolando González-José Andrés Ruiz-Linares Samuel Canizales-Quinteros Sandra Romero-Hidalgo Johannes Krause Joaquín Zúñiga Edmond J Yunis Carolina Bekker-Méndez Julio Granados

Hum Immunol 2020 Jul 7. Epub 2020 Jul 7.

Department of Transplantation, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" (INCMNSZ), Mexico City, Mexico. Electronic address:

We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) allele groups and alleles by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of the country divided into 78 sample sets, providing information regarding allelic and haplotypic frequencies and their linkage disequilibrium, as well as admixture estimates and genetic substructure. We identified the presence of 4268 unique HLA extended haplotypes across Mexico and find that the ten most frequent (HF > 1%) HLA haplotypes with significant linkage disequilibrium (Δ'≥0.1) in Mexico (accounting for 20% of the haplotypic diversity of the country) are of primarily Native American ancestry (A*02~B*39~DRB1*04~DQB1*03:02, A*02~B*35~DRB1*08~DQB1*04, A*68~B*39~DRB1*04~DQB1*03:02, A*02~B*35~DRB1*04~DQB1*03:02, A*24~B*39~DRB1*14~DQB1*03:01, A*24~B*35~DRB1*04~DQB1*03:02, A*24~B*39~DRB1*04~DQB1*03:02, A*02~B*40:02~DRB1*04~DQB1*03:02, A*68~B*35~DRB1*04~DQB1*03:02, A*02~B*15:01~DRB1*04~DQB1*03:02). Read More

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http://dx.doi.org/10.1016/j.humimm.2020.06.008DOI Listing

The impact of historical racism on modern gun violence: Redlining in the city of Louisville, KY.

Injury 2020 Jun 25. Epub 2020 Jun 25.

Department of Surgery, University of Louisville School of Medicine, 530 South Jackson Street, Louisville, KY 40203. Electronic address:

Background: The Home Owner's Loan Corporation (HOLC) was created in 1933 to provide government backing of troubled mortgages during the Great Depression. Residential security maps were created to guide investment in over 200 US cities. Neighborhoods were assigned grades of 'A' through 'D' (with corresponding color coding of green, blue, yellow and red) to indicate desirability for investment. Read More

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http://dx.doi.org/10.1016/j.injury.2020.06.042DOI Listing

Clinicopathologic implications of Myb and Beta-catenin expression in adenoid cystic carcinoma.

J Otolaryngol Head Neck Surg 2020 Jul 10;49(1):48. Epub 2020 Jul 10.

Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, California, USA.

Background: Adenoid cystic carcinoma (ACC) is the second most common malignancy of the salivary glands, accounting for ~ 1% of malignant tumors of the head and neck region and 10% of salivary gland neoplasms. Predicting the long-term outcomes of patients with ACC is still challenging, as reliable prognostic biomarkers are not available. Among salivary gland tumors, Myb overexpression is highly specific for ACC. Read More

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http://dx.doi.org/10.1186/s40463-020-00446-1DOI Listing

Consumption of non-nutritive sweeteners by pre-schoolers of the food and environment Chilean cohort (FECHIC) before the implementation of the Chilean food labelling and advertising law.

Nutr J 2020 Jul 10;19(1):69. Epub 2020 Jul 10.

Institute of Nutrition and Food Technology, University of Chile, Av. El Líbano 5524, Macul, Casilla 138-11, Santiago, Chile.

Background: Consumption of non-nutritive sweeteners (NNS) is becoming increasingly more frequent, particularly in the context of obesity prevention policies. The aim of this study was to describe the consumption of NNS in an ongoing cohort of pre-schoolers (4-6-year-old) before the implementation of the Chilean Food Labelling and Advertising Law, identify sociodemographic and anthropometric characteristics associated with their consumption, and describe the main dietary sources of each NNS sub-type.

Methods: In 959 low-medium income pre-schoolers from the Food and Environment Chilean Cohort (FECHIC), dietary data from a single 24-h recall was linked to NNS content information obtained from packaged foods (n = 12,233). Read More

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http://dx.doi.org/10.1186/s12937-020-00583-3DOI Listing

Incremental validity of coronaphobia: Coronavirus anxiety explains depression, generalized anxiety, and death anxiety.

J Anxiety Disord 2020 Jul 1;74:102268. Epub 2020 Jul 1.

Christopher Newport University, United States.

The adverse psychological effects of COVID-19 have increased globally. Moreover, the psychological toll may be worsening for this health crisis due to the growing numbers of mass deaths and unemployment levels. Coronaphobia, a relatively new pandemic-related construct, has been shown to be strongly related to functional impairment and psychological distress. Read More

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http://dx.doi.org/10.1016/j.janxdis.2020.102268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328548PMC

Perfluoroalkyl substances in the Yangtze River: Changing exposure and its implications after operation of the Three Gorges Dam.

Water Res 2020 May 16;182:115933. Epub 2020 May 16.

College of Environmental Sciences and Engineering, Peking University, The Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing 100871, China; School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, China. Electronic address:

Potential ecological risk from perfluoroalkyl substances (PFASs) under changing exposure in large river systems has become a new challenge recently. Based on systematic monitoring of PFASs at 43 hydrologic stations along a 4300 km continuum of the Yangtze River, we investigated the ecological risk of PFASs under changing exposure resulting from operation of the Three Gorges Dam (TGD). Importantly, perfluorooctanoic acid (PFOA) was found extensively exposed in most mainstream water samples, accounting for about 90% of the total content of PFASs in both spring and autumn, while short-chain PFASs contributed more than PFOA in sediment. Read More

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http://dx.doi.org/10.1016/j.watres.2020.115933DOI Listing

Efficacy of the modified frailty index and the modified Charlson comorbidity index in predicting complications in patients undergoing operative management of proximal humerus fracture.

J Shoulder Elbow Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Orthopaedic Surgery, Loma Linda University Medical Center, Loma Linda, CA, USA. Electronic address:

Background: Comorbidity indices such as the 5-factor modified Frailty Index (mFI-5) and modified Charlson Comorbidity Index (mCCI) are widely used in outcomes research.

Methods: 3,893 patients who underwent total shoulder arthroplasty (TSA, n=975), hemiarthroplasty (HA, n=495), or open reduction and internal fixation (ORIF, n=2,423) for the treatment of proximal humerus fracture (PHFx) from 2005-2017 were identified from the National Surgical Quality Improvement Program (NSQIP) database. Data regarding demographics, comorbidities, ASA class, and postoperative complications were collected, and the mFI-5 and mCCI were calculated for each case. Read More

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http://dx.doi.org/10.1016/j.jse.2020.06.014DOI Listing

The Ulnar Collateral Ligament Responds to Stress in Professional Pitchers.

J Shoulder Elbow Surg 2020 Jul 7. Epub 2020 Jul 7.

Director of Baseball Science, Los Angeles Angels, Anaheim, CA, USA.

Background: Our purpose with this study was to determine the response of the UCL in professional pitchers following exposure to a season of pitching and to rest during an off-season.

Methods: In a prospective study supported by Major League Baseball, all pitchers within a single professional baseball club were enrolled. An ultrasound (US) of the ligament was then performed by a single fellowship-trained ultrasonographer at the beginning of the season (T1), the end of the season (T2), and the beginning of the following season (T3). Read More

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http://dx.doi.org/10.1016/j.jse.2020.06.027DOI Listing

Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries.

PLoS One 2020 10;15(7):e0236064. Epub 2020 Jul 10.

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.

Background: The best management of hypertension in frail oldest-old (≥80 years of age) remains unclear and we still lack guidelines that provide specific recommendations. Our study aims to investigate guideline use in general practitioners (GPs) and to examine if guideline use relates to different decisions when managing hypertension in frail oldest-old.

Design/setting: Cross-sectional study among currently active GPs from 29 countries using a case-vignettes survey. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236064PLOS

Measuring the drafting alignment of patent documents using text mining.

PLoS One 2020 10;15(7):e0234618. Epub 2020 Jul 10.

Division of Accounting and Law, Babson College, Babson Park, Massachusetts, United States of America.

How would an inventor, entrepreneur, investor, or patent examiner quantify the extent to which the inventive claims listed in a patent document align with patent specification? Since a specification that is poorly aligned with the inventive claims can render an invention unpatentable and can invalidate an already issued patent, an effective measure of alignment is necessary. We define a novel measure of drafting alignment using Latent Dirichlet Allocation (LDA). The measure is defined for each patent document by first identifying the latent topics underlying the claims and the specification, and then using the Hellinger distance to find the proximity between the topical coverages. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234618PLOS

Scoring Interpersonal Violence Measures: Methodological Considerations.

Nurs Res 2020 Jul 2. Epub 2020 Jul 2.

Assistant Professor, University of North Carolina at Chapel Hill School of Nursing, Chapel Hill, NC Assistant Professor, University of California, Irvine, Sue & Bill Gross School of Nursing, Irvine, CA Assistant Professor, Pennsylvania State University College of Nursing, University Park, PA Associate Professor, Duke University School of Nursing, Durham, NC.

Background: Interpersonal violence, such as intimate partner violence, sexual assault, and adverse childhood experiences, is a significant global health concern. A major challenge to nurses and others working in the field of interpersonal violence deals with the complexity involved in measuring interpersonal violence. Numerous validated instruments exist; however, there is no standard approach for scoring these instruments. Read More

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http://dx.doi.org/10.1097/NNR.0000000000000461DOI Listing

Impact of Socioeconomic Position on Access to the US Lung Transplant Waiting List in a Matched Cystic Fibrosis Cohort.

Ann Am Thorac Soc 2020 Jul 10. Epub 2020 Jul 10.

Cleveland Clinic , Pulmonary Medicine , Cleveland , Ohio, United States;

Rationale: Referrals for lung transplant and transplant rates in the United States are lower than in Canada for patients with advanced cystic fibrosis (CF) lung disease. Further study of factors limiting access are needed to optimize referral and transplant for this population.

Objective(s): To determine the effect of socioeconomic position, while accounting for disease severity, on the likelihood of wait-listing for lung transplant in the United States. Read More

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http://dx.doi.org/10.1513/AnnalsATS.202001-030OCDOI Listing

Phytoestrogen intake and other dietary risk factors for low motile sperm count and poor sperm morphology.

Andrology 2020 Jul 10. Epub 2020 Jul 10.

Division of Preventive Medicine, University of Alberta, Edmonton, Canada.

Background: Few potentially modifiable risk factors of male infertility have been identified and while different diets and food groups have been associated with male infertility, evidence linking dietary factors including phytoestrogens and semen quality is limited and contradictory.

Objectives: To study the associations between phytoestrogen intake and other dietary factors and semen quality.

Materials And Methods: A case-referent study was undertaken of the male partners, of couples attempting conception with unprotected intercourse for 12 months or more without success, recruited from 14 UK assisted reproduction clinics. Read More

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http://dx.doi.org/10.1111/andr.12858DOI Listing

Cerebrovascular Perfusion among Older Adults with and Without Cardiovascular Disease.

J Neuroimaging 2020 Jul 10. Epub 2020 Jul 10.

Department of Psychology, University of Georgia, Athens, GA.

Background And Purpose: Cardiovascular disease (CVD) encompasses a range of disorders that affect health and functioning in older adults. While cognitive declines have been linked to both cardiovascular and cerebral blood perfusion, protective neurovascular mechanisms raise the question whether cerebrovascular perfusion differs as a function of cardiovascular health status. The present study examined whether cerebrovascular perfusion significantly differs between healthy older adults with and without diagnosed CVD. Read More

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http://dx.doi.org/10.1111/jon.12757DOI Listing

Influenza sequelae: from immune modulation to persistent alveolitis.

Clin Sci (Lond) 2020 Jul;134(13):1697-1714

Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, U.S.A.

Acute influenza virus infections are a global public health concern accounting for millions of illnesses worldwide ranging from mild to severe with, at time, severe complications. Once an individual is infected, the immune system is triggered in response to the pathogen. This immune response can be beneficial ultimately leading to the clearance of the viral infection and establishment of immune memory mechanisms. Read More

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http://dx.doi.org/10.1042/CS20200050DOI Listing

Distribution of metal contamination and grain size in the sediments of Nakdong River, Korea.

Environ Monit Assess 2020 Jul 9;192(8):502. Epub 2020 Jul 9.

Nakdong River Environment Research Center, National Institute of Environmental Research, 24-11, Gukgasandan-daero 52-gil, Guji-myeon, Dalseong-gun, Daegu, Republic of Korea.

To assess distribution of metal contamination and grain size in the sediments of Nakdong River (South Korea), surface sediments were collected from 21 sites and analyzed. Within the study area, sand was typically the dominant grain size. However, because of the reduced flow rate and flow velocity, sites adjacent to weirs were composed of relatively fine sediments. Read More

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http://dx.doi.org/10.1007/s10661-020-08475-zDOI Listing

Refractive state and visual acuity of children with extremely low birth weight at 3 years old in Japan.

Jpn J Ophthalmol 2020 Jul 10. Epub 2020 Jul 10.

Office for Clinical Research Support, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.

Purpose: To investigate the refractive status and visual acuity of 3-year-old children with extremely low birth weight (ELBW).

Study Design: Retrospective cohort study.

Methods: We examined 161 children born between January 2009 and December 2014. Read More

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http://dx.doi.org/10.1007/s10384-020-00754-zDOI Listing

Establishment and characterization of NCC-ASPS1-C1: a novel patient-derived cell line of alveolar soft-part sarcoma.

Hum Cell 2020 Jul 10. Epub 2020 Jul 10.

Division of Rare Cancer Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Alveolar soft-part sarcoma is a mesenchymal malignancy characterized by the rearrangement of ASPSCR1 and TFE3 and a histologically distinctive pseudoalveolar pattern. Although alveolar soft-part sarcoma takes an indolent course, its long-term prognosis is poor because of late distant metastases. Currently, curative treatments have not been found for alveolar soft-part sarcoma, and hence, a novel therapeutic strategy has long been required. Read More

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http://dx.doi.org/10.1007/s13577-020-00382-2DOI Listing

DNA Chisel, a versatile sequence optimizer.

Bioinformatics 2020 Jul 9. Epub 2020 Jul 9.

Edinburgh Genome Foundry, SynthSys, School of Biological Sciences, University of Edinburgh, EH93BF Edinburgh, UK.

Motivation: Accounting for biological and practical requirements in DNA sequence design often results in challenging optimization problems. Current software solutions are problem-specific and hard to combine.

Results: DNA Chisel is an easy-to-use, easy-to-extend sequence optimization framework allowing to freely define and combine optimization specifications via Python scripts or Genbank annotations. Read More

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http://dx.doi.org/10.1093/bioinformatics/btaa558DOI Listing

Prescription Patterns and Risk Factors for Prolonged Opioid Dependence in Elective Anterior Cruciate Ligament Reconstruction in a Military Population.

Orthop J Sports Med 2020 Jun 29;8(6):2325967120926489. Epub 2020 Jun 29.

Department of Surgery Division of Orthopaedics, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

Background: Limited data are available regarding excessive opioid prescribing in the perioperative period after routine orthopaedic procedures in US military personnel.

Purpose: To examine the demographic profile of the patients receiving these medications and to identify potential risk factors for prolonged opioid use after anterior cruciate ligament reconstruction (ACLR) in the active duty military population.

Study Design: Case-control study; Level of evidence, 3. Read More

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http://dx.doi.org/10.1177/2325967120926489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325468PMC

Analysis of the clinical characteristics of 176 patients with pathologically confirmed cryptogenic organizing pneumonia.

Ann Transl Med 2020 Jun;8(12):763

Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University, School of Medicine, Shanghai, China.

Background: Cryptogenic organizing pneumonia (COP), is a form of idiopathic interstitial pneumonia (IIP) and is diagnosed by clinical-radiologic-pathologic (CRP) diagnosis. To summarize the clinical, imaging, pathological, and prognostic characteristics of 176 patients with confirmed COP.

Methods: Patients who were diagnosed with organizing pneumonia (OP) by lung biopsy between January 1, 2000, and December 31, 2013, in our hospital were retrospectively analyzed and followed up until 12/31/2017. Read More

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http://dx.doi.org/10.21037/atm-20-4490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333162PMC

Lighting system bioinspired by Haworthia obtusa.

Sci Rep 2020 Jul 9;10(1):11246. Epub 2020 Jul 9.

Department of Mechanical Engineering, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-ku, Tokyo, 135-8548, Japan.

Electricity plays an important role in modern societies, with lighting and illumination accounting for approximately one-fifth of the global demand for electricity. Haworthia obtusa has the remarkable ability to collect solar light through a so-called 'window' which allows it to photosynthesise in the dark. Inspired by this unique characteristic, we developed a novel lighting system that does not use electricity. Read More

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http://dx.doi.org/10.1038/s41598-020-68196-8DOI Listing

Attrition from specialised rehabilitation associated with an elevated mortality risk: results from a vital status tracing study in Swiss spinal cord injured patients.

BMJ Open 2020 Jul 9;10(7):e035752. Epub 2020 Jul 9.

Swiss Paraplegic Research, Nottwil, Switzerland.

Introduction: Study drop-out and attrition from treating clinics is common among persons with chronic health conditions. However, if attrition is associated with adverse health outcomes, it may bias or mislead inferences for health policy and resource allocation.

Methods: This retrospective cohort study uses data attained through the Swiss Spinal Cord Injury (SwiSCI) cohort study on persons with spinal cord injury (SCI). Read More

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http://dx.doi.org/10.1136/bmjopen-2019-035752DOI Listing

Prognostic Impact of Race in Patients Undergoing PCI: Analysis From 10 Randomized Coronary Stent Trials.

JACC Cardiovasc Interv 2020 Jul;13(13):1586-1595

Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

Objectives: The aim of this study was to assess race-based differences in patients undergoing percutaneous coronary intervention from a large pooled database of randomized controlled trials.

Background: Data on race-based outcomes after percutaneous coronary intervention are limited, deriving mainly from registries and single-center studies.

Methods: Baseline characteristics and outcomes at 30 days, 1 year, and 5 years were assessed across different races, from an individual patient data pooled analysis from 10 randomized trials. Read More

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http://dx.doi.org/10.1016/j.jcin.2020.04.020DOI Listing

Surgical management of acetabular fractures - A contemporary literature review.

Injury 2020 Jun 24. Epub 2020 Jun 24.

Royal Adelaide Hospital, Orthopaedic Trauma, Adelaide, Australia; The University of Adelaide, Trauma & Orthopaedics, Adelaide, Australia.

Surgical management of acetabular fractures is now commonplace for almost all displaced or unstable fractures. Over the last 20 years however, the patient population has aged, and there have been significant changes to safety in motor vehicles and the work-place, and people's activity types and levels have changed. The surgical specialty has also developed with time, and as a result acetabular fracture surgery today is different to 20 years ago. Read More

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http://dx.doi.org/10.1016/j.injury.2020.06.016DOI Listing

Zinc Level and Its Role in Recurrent Infection: A Case Report and Literature Review.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620941315

Geisinger Lewistown Hospital, Lewistown, PA, USA.

infection is a common nosocomial infection in US hospitals, accounting for approximately 12 800 deaths annually in the United States. These infections are often associated with the use of antibiotics, which can alter the gut microbiome and thus render patients susceptible to infection. is often spread via fecal oral transmission. Read More

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http://dx.doi.org/10.1177/2324709620941315DOI Listing

Exosomal MicroRNAs and Organotropism in Breast Cancer Metastasis.

Cancers (Basel) 2020 Jul 7;12(7). Epub 2020 Jul 7.

Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.

Breast cancer is the most frequent malignancy for women in which one in eight women will be diagnosed with the disease in their lifetime. Despite advances made in treating primary breast cancer, there is still no effective treatment for metastatic breast cancer. Consequently, metastatic breast cancer is responsible for 90% of breast cancer-related deaths while only accounting for approximately one third of all breast cancer cases. Read More

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http://dx.doi.org/10.3390/cancers12071827DOI Listing