48,305 results match your criteria Abstracts Published in Conference Program [Journal]


Meta-Analysis: 13-Year Follow-Up of Psychotherapy Effects on Youth Depression.

J Am Acad Child Adolesc Psychiatry 2019 Apr 17. Epub 2019 Apr 17.

Objective: Youth depression is a debilitating condition that constitutes a major public health concern. A 2006 meta-analysis found modest benefits for psychotherapy vs. control. Read More

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http://dx.doi.org/10.1016/j.jaac.2019.04.002DOI Listing

A systematic review of measures of therapist competence in psychodynamic, interpersonal, and/or relational models.

Psychol Psychother 2019 Apr 19. Epub 2019 Apr 19.

Centre for New Treatments and Understanding in Mental Health (CeNTrUM), School of Health Sciences, University of Manchester, UK.

Purpose: Assessment of psychotherapeutic competence is increasingly regarded as important in the delivery of psychological services and training programmes. This article reviews tools designed to assess clinical competence in psychodynamic, interpersonal, and relational models of therapy.

Methods: PsycINFO, CINAHL, and Web of Science online databases were reviewed using terms relating to competence, psychotherapy, and measurement. Read More

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http://dx.doi.org/10.1111/papt.12231DOI Listing

Use of Immunosuppressive therapy for management of myelodysplastic syndromes: a systematic review and meta-analysis.

Haematologica 2019 Apr 19. Epub 2019 Apr 19.

Department of Internal Medicine, Section of Hematology, Yale School of Medicine;

Immunosuppressive therapy is one therapy option for treatment of patients with lower-risk myelodysplastic syndromes. However, the use of several different immunosuppressive regimens, the lack of high-quality studies, and the absence of validated predictive biomarkers pose important challenges. We conducted a systematic review and meta-analysis according to the Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines and searched MEDLINE via PubMed, Ovid EMBASE, COCHRANE registry of clinical trials (CENTRAL), and the Web of Science without language restriction from inception through September 2018 as well as relevant conference proceedings and abstracts. Read More

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http://dx.doi.org/10.3324/haematol.2019.219345DOI Listing

Rapidly decreasing prevalence of Helicobacter pylori among Japanese children and adolescents.

J Infect Chemother 2019 Apr 16. Epub 2019 Apr 16.

Department of Public Health, Aichi Medical University School of Medicine, Japan. Electronic address:

Background: The secular trend in the prevalence of Helicobacter pylori (H. pylori) infection among children and adolescents in Japan has not been well documented.

Materials And Methods: We reviewed all relevant literature published between 1991 and 2017, focusing on the relationship between the prevalence of H. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.02.016DOI Listing

The effectiveness of group exercise for improving activity and participation in adult stroke survivors: a systematic review.

Physiotherapy 2019 Jan 19. Epub 2019 Jan 19.

School of Health and Related Research (ScHARR), University of Sheffield, Regent Court, 30 Regent Street, Sheffield, South Yorkshire S14DA, United Kingdom. Electronic address:

Background: Following post stroke rehabilitation, group exercise interventions can be used to continue improving cardiovascular fitness, activity levels, balance, gait, movement efficiency, and strengthening. However, little is known of the effectiveness of group exercise for improving activity and participation in stroke survivors.

Objectives: This review aims to assess the effectiveness of group exercise for improving activity and participation in adult stroke survivors. Read More

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http://dx.doi.org/10.1016/j.physio.2019.01.005DOI Listing
January 2019

Augmented and virtual reality in dental medicine: A systematic review.

Comput Biol Med 2019 Mar 15;108:93-100. Epub 2019 Mar 15.

Department of Reconstructive Dentistry, University Center for Dental Medicine Basel, University of Basel, Switzerland, Hebelstr. 3, CH-4056, Basel, Switzerland.

Background: The aim of this systematic review was to provide an update on the contemporary knowledge and scientific development of augmented reality (AR) and virtual reality (VR) in dental medicine, and to identify future research needs to accomplish its clinical translation.

Method: A modified PICO-strategy was performed using an electronic (MEDLINE, EMBASE, CENTRAL) plus manual search up to 12/2018 exploring AR/VR in dentistry in the last 5 years. Inclusion criteria were limited to human studies focusing on the clinical application of AR/VR and associated field of interest in dental medicine. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2019.03.012DOI Listing

Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.

Cochrane Database Syst Rev 2019 Apr 19;4:CD011385. Epub 2019 Apr 19.

Van Creveldkliniek / Department of Haematology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, Netherlands, 3584CT.

Background: Minor oral surgery or dental extractions (oral or dental procedures) are widely performed and can be complicated by hazardous oral bleeding, especially in people with an inherited bleeding disorder such as haemophilia or Von Willebrand disease (VWD). The amount and severity of singular bleedings depend on disease-related factors, such as the severity of the haemophilia, both local and systemic patient factors (such as periodontal inflammation, vasculopathy or platelet dysfunction) and intervention-related factors (such as the type and number of teeth extracted or the dimension of the wound surface). Similar to local haemostatic measures and suturing, antifibrinolytic therapy is a cheap, safe and potentially effective treatment to prevent bleeding complications in individuals with bleeding disorders undergoing oral or dental procedures. Read More

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http://dx.doi.org/10.1002/14651858.CD011385.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474399PMC

A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR.

Biomed Res Int 2019 14;2019:6074984. Epub 2019 Mar 14.

Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Background: Four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) is a noninvasive novel imaging technology that can be used to visualise and assess right ventricular function. The aim of this systematic review is to summarise the literature available on 4D flow CMR methods used to determine right ventricular diastolic function.

Methods: A systematic review of current literature was carried out to ascertain what is known about right ventricular assessment by quantification of 4D flow CMR. Read More

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https://www.hindawi.com/journals/bmri/2019/6074984/
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http://dx.doi.org/10.1155/2019/6074984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437735PMC
March 2019
1 Read

2019 Annual Session Semifinalists? Research Abstracts.

Authors:

Pediatr Dent 2019 Mar;41(2):152-156

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Understanding patient engagement in health system decision-making: a co-designed scoping review.

Syst Rev 2019 Apr 18;8(1):97. Epub 2019 Apr 18.

The Department Community Health Sciences, Teaching Research and Wellness Building, 3280 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada.

Background: With healthcare striving to shift to a more person-centered delivery model, patient and family involvement must have a bigger role in shaping this. While many initiatives involving patients and family members focus on self-care, a broader understanding of patient participation is necessary. Ensuring a viable and sustainable critical number of qualified patients and family members to support this shift will be of utmost importance. Read More

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https://systematicreviewsjournal.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/s13643-019-0994-8DOI Listing
April 2019
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Social capital components and social support of persons with multiple sclerosis: a systematic review of the literature from 2000 to 2018.

Disabil Rehabil 2019 Apr 18:1-13. Epub 2019 Apr 18.

c Neurology, Public Health, Disability Unit and Coma Research Centre , Fondazione IRCCS Istituto Neurologico Carlo Besta , Milan , Italy.

Purpose: To identify experiences of persons with multiple sclerosis (MS) in terms of social capital and its components (i.e., social networks, trust, and interpersonal relationships) and social support based on the current scientific knowledge. Read More

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http://dx.doi.org/10.1080/09638288.2019.1597182DOI Listing

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma.

Cochrane Database Syst Rev 2019 Apr 19;4:CD011875. Epub 2019 Apr 19.

Ophthalmology, Singapore National Eye Centre, Singapore, Singapore.

Background: Glaucoma affects more than 70 million people worldwide, with about 10% being bilaterally blind, making it the leading cause of irreversible blindness globally. In patients with advanced glaucoma or those who have failed medical treatment without achieving adequate intraocular pressure (IOP) control, trabeculectomy (glaucoma filtration surgery where an ostium is created into the anterior chamber from underneath a partial thickness scleral flap to allow for aqueous flow out of the anterior chamber intointo the subconjunctival space forming a filtering bleb) and aqueous shunt surgery for more complex and refractory cases remain the mainstay therapies. Proliferation of fibrous tissue around an implanted aqueous shunt may block the diffusion of aqueous humour. Read More

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http://doi.wiley.com/10.1002/14651858.CD011875.pub2
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http://dx.doi.org/10.1002/14651858.CD011875.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472957PMC
April 2019
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Child sexual abuse, disclosure and PTSD: A systematic and critical review.

Child Abuse Negl 2019 Apr 15;92:196-208. Epub 2019 Apr 15.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.

Background: Child sexual abuse (CSA) is a prevalent exposure with potentially serious, negative health consequences, including post-traumatic stress disorder (PTSD) and its symptomatology.

Objective: To conduct a systematic and critical review in order to investigate the relationship between CSA disclosure patterns and PTSD.

Participants And Setting: Studies included clinical, college and community-based samples of adults' and children's experiences of CSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01452134193013
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http://dx.doi.org/10.1016/j.chiabu.2019.04.006DOI Listing
April 2019
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Detecting pathological complete response in esophageal cancer after neoadjuvant therapy based on imaging techniques: a diagnostic systematic review and meta-analysis.

J Thorac Oncol 2019 Apr 15. Epub 2019 Apr 15.

Department of surgery.

Background: Up to 32% of patients with esophageal cancer show a pathological complete response (ypCR) after neoadjuvant therapy. In order to prevent overtreatment, the indication to perform esophagectomy in these patients should be reconsidered. Implementing an organ preserving strategy for patients with ypCR requires an accurate assessment of residual disease after neoadjuvant treatment. Read More

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http://dx.doi.org/10.1016/j.jtho.2019.04.004DOI Listing

Incidence and factors associated with substance abuse and patient-related violence in the emergency department: A literature review.

Australas Emerg Care 2018 Nov 2;21(4):159-170. Epub 2018 Nov 2.

Austin Clinical School of Nursing, La Trobe University, Heidelberg, Victoria, Australia.

Background: The level of workplace violence in emergency departments worldwide has reached an alarming level. Substance abuse is thought to play a major part in the escalation of aggressive and violent behaviour and is suspected to be responsible for the majority of violent escalations in the emergency department. The aim of this scoping review was (1) to investigate the incidence of workplace violence in the emergency department, their association to substance abuse and (2) to identify factors associated with workplace violence such as perpetrator characteristics and environmental factors. Read More

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http://dx.doi.org/10.1016/j.auec.2018.10.004DOI Listing
November 2018
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Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus.

Cochrane Database Syst Rev 2019 Apr 18;4:CD012368. Epub 2019 Apr 18.

Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen N, Denmark, 2200.

Background: The number of people with type 2 diabetes mellitus (T2DM) is increasing worldwide. The combination of metformin and sulphonylurea (M+S) is a widely used treatment. Whether M+S shows better or worse effects in comparison with other antidiabetic medications for people with T2DM is still controversial. Read More

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http://dx.doi.org/10.1002/14651858.CD012368.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472662PMC

Defining Frailty in Research Abstracts: A Systematic Review and Recommendations for Standardization.

J Frailty Aging 2019 ;8(2):67-71

Ariela R. Orkaby, MD MPH, Instructor in Medicine, Harvard Medical School, Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, 150 South Huntington St, Boston, MA 02130 USA, Phone: 857-364-3646; Fax: 857-364-2784, Email:

Multiple definitions of frailty are used. We sought to quantify the frequency that frailty is insufficiently defined in published abstracts. We conducted a systematic review of MEDLINE/PubMed for English abstracts of original research investigating frailty as an exposure or outcome in humans from 2015-2017. Read More

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http://dx.doi.org/10.14283/jfa.2019.4DOI Listing
January 2019

Systematic Review of Lesser Known Parasitoses: Maxillofacial Dirofilariasis.

J Maxillofac Oral Surg 2019 Jun 2;18(2):180-189. Epub 2018 Aug 2.

6Department of Pathology, AIIMS Jodhpur, Jodhpur, India.

Background: Dirofilariasis is an endemic disease in tropical and subtropical countries caused by about 40 different species of dirofilari. Dirofilariasis of the oral cavity is extremely rare and is usually seen as mucosal or submucosal nodules. We also present a case of dirofilariasis of the mandibular third molar region submucosally in a 26 year old male patient. Read More

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http://dx.doi.org/10.1007/s12663-018-1139-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441424PMC

Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis.

F1000Res 2018 30;7:1359. Epub 2018 Aug 30.

Division of Infectious Diseases, Geneva University Hospital, Geneva, 1205, Switzerland.

Dolutegravir-containing maintenance therapy is a promising simplification strategy for virologically suppressed HIV-infected individuals. However, most of the available data to inform this strategy come from small, uncontrolled studies. We estimated the proportion of HIV-infected patients experiencing virological failure (VF) and developing drug resistance on dolutegravir (DTG)-based maintenance therapy. Read More

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https://f1000research.com/articles/7-1359/v1
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http://dx.doi.org/10.12688/f1000research.15995.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134332.2PMC
August 2018
6 Reads

Guidelines for Postoperative care in Cesarean Delivery: Enhanced Recovery After Surgery (ERAS) Society Recommendations (Part 3 ).

Am J Obstet Gynecol 2019 Apr 14. Epub 2019 Apr 14.

Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, United States.

This Enhanced Recovery After Surgery (ERAS) Guideline for postoperative care in Cesarean Delivery (CD) will provide best practice, evidenced-based, recommendations for post-operative care with, primarily a maternal focus. The pathway process for scheduled and unscheduled CD, for this ERAS CD guideline, will consider time from completion of cesarean until maternal hospital discharge. The literature search (1966-2017) used Embase and PubMed to search medical subject headings including "Cesarean Section", "Cesarean Delivery", "Cesarean Section Delivery" and all post-operative ERAS® items. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193057
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http://dx.doi.org/10.1016/j.ajog.2019.04.012DOI Listing
April 2019
2 Reads

Coverage of ethics within the artificial intelligence and machine learning academic literature: The case of disabled people.

Assist Technol 2019 Apr 17:1-7. Epub 2019 Apr 17.

a Community Rehabilitation and Disability Studies, Department of Community Health Sciences, Cumming School of Medicine , University of Calgary , Calgary , Alberta , Canada.

Disabled people are often the anticipated users of scientific and technological products and processes advanced and enabled by artificial intelligence (AI) and machine learning (ML). Disabled people are also impacted by societal impacts of AI/ML. Many ethical issues are identified within AI/ML as fields and within individual applications of AI/ML. Read More

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http://dx.doi.org/10.1080/10400435.2019.1593259DOI Listing

Mechanistic study of the reaction of CHF with Cl atoms in the absence and presence of CH or CH: decomposition of CHFOH and fate of the CHFO radical.

Phys Chem Chem Phys 2019 Apr 17. Epub 2019 Apr 17.

Department of Chemical Engineering, University of Melbourne, Victoria 3010, Australia.

To assess the atmospheric fate of fluorinated compounds, chamber experiments were performed with Fourier transform infrared spectroscopy investigating the products of difluoromethane, CH2F2, at 296 ± 2 K. The reactions were initiated by reaction of CH2F2 with Cl atoms in the absence and presence of CH4 or C2H6 in air or O2. No evidence of formation of the fluorinated alcohol, CHF2OH, from the reactions of the CHF2O2 radical with either CH3O2 or CH3CH2O2 was observed. Read More

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http://dx.doi.org/10.1039/c8cp06425cDOI Listing

Linking Bisphenol S to Adverse Outcome Pathways Using a Combined Text Mining and Systems Biology Approach.

Environ Health Perspect 2019 Apr;127(4):47005

1 University Paris Descartes , ComUE Sorbonne Paris Cité, Paris, France.

Background: Available toxicity data can be optimally interpreted if they are integrated using computational approaches such as systems biology modeling. Such approaches are particularly warranted in cases where regulatory decisions have to be made rapidly.

Objectives: The study aims at developing and applying a new integrative computational strategy to identify associations between bisphenol S (BPS), a substitute for bisphenol A (BPA), and components of adverse outcome pathways (AOPs). Read More

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https://ehp.niehs.nih.gov/doi/10.1289/EHP4200
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http://dx.doi.org/10.1289/EHP4200DOI Listing
April 2019
2 Reads

Fertility preservation in female cancer patients-state of the art.

Minerva Ginecol 2019 Apr 15. Epub 2019 Apr 15.

Department for Gynecology, Obstetrics and Reproductive Medicine, University Hospital of Saarland, Homburg, Germany.

Protecting fertility in the presence of cancer has become highly significant, as the desire to give birth to a child is increasingly postponed to later in life, and long-term survival with cancer has increased. A variety of fertility-preserving methods have been developed. To find them we did a literature search in Medline with the term "female fertility preservation in cancer" in December 2017. Read More

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https://www.minervamedica.it/index2.php?show=R09Y9999N00A190
Publisher Site
http://dx.doi.org/10.23736/S0026-4784.19.04387-9DOI Listing
April 2019
1 Read

Passive Ultrasonic Irrigation Efficacy in the Vapor Lock Removal: Systematic Review and Meta-Analysis.

ScientificWorldJournal 2019 12;2019:6765349. Epub 2019 Mar 12.

Department of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy.

Passive Ultrasonic Irrigation (PUI) represents one of the most used systems to improve the endodontic irrigants activity. PUI acts increasing the reaction rate of NaOCl, with an increase of dentinal debris and smear layer removal. There is a stronger shear stress and a vapor lock reduction. Read More

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http://dx.doi.org/10.1155/2019/6765349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434262PMC

Practical Implications of New Antibiotic Agents for the Treatment of Carbapenem-Resistant Enterobacteriaceae.

Microbiol Insights 2019 4;12:1178636119840367. Epub 2019 Apr 4.

Department of Clinical Health Professions, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.

Objective: To provide insight into the practical implications of the use of ceftazidime/avibactam and meropenem/vaborbactam for the management of carbapenem-resistant Enterobacteriaceae (CRE) and to identify strategies for overcoming barriers to the use of these agents in clinical practice.

Data Sources: A literature search of PubMed was conducted using the following search terms: ceftazidime/avibactam, meropenem/vaborbactam, carbapenem-resistant Enterobacteriaceae, antimicrobial stewardship, and clinical laboratory standards institute. Abstracts from infectious diseases conferences, article bibliographies, and relevant drug monographs were also reviewed. Read More

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http://dx.doi.org/10.1177/1178636119840367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449805PMC

Effects of high-fat diets on fetal growth in rodents: a systematic review.

Reprod Biol Endocrinol 2019 Apr 16;17(1):39. Epub 2019 Apr 16.

Department of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.

Background: Maternal nutrition during pregnancy has life-long consequences for offspring. However, the effects of maternal overnutrition and/ or obesity on fetal growth remain poorly understood, e.g. Read More

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http://dx.doi.org/10.1186/s12958-019-0482-yDOI Listing

Cognitive Function in Primary Sjögren's Syndrome: A Systematic Review.

Brain Sci 2019 Apr 15;9(4). Epub 2019 Apr 15.

Department of Old Age Psychiatry, Central and North West London NHS Foundation Trust, London UB8 3NN, UK.

Background: Cognitive disorders are reported to be common in patients with primary Sjogren's syndrome (pSS). In some cases, they are the first clinical manifestation, preceding the diagnosis of pSS by two years on average.

Aim: A systematic review was conducted to explore cognitive impairment in pSS, with reference to diagnostic methods and their relationship with laboratory data and clinical manifestations. Read More

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http://dx.doi.org/10.3390/brainsci9040085DOI Listing
April 2019
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A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements.

Environ Res 2019 Apr 8;173:528-538. Epub 2019 Apr 8.

Child Health, University of Aberdeen, Aberdeen, UK. Electronic address:

Background: Reduced birth weight is associated with many maternal environmental exposures during pregnancy, but the gestational age at onset of this association is unknown. We have previously reported associations between maternal smoking and fetal size.

Objective: To report on our systematic review of the literature describing associations between antenatal size and growth and maternal exposures during pregnancy. Read More

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http://dx.doi.org/10.1016/j.envres.2019.04.005DOI Listing
April 2019
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A review of measurement practice in studies of clinical decision support systems 1998-2017.

J Am Med Inform Assoc 2019 Apr 16. Epub 2019 Apr 16.

Schools of Medicine, Information and Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Objective: To assess measurement practice in clinical decision support evaluation studies.

Materials And Methods: We identified empirical studies evaluating clinical decision support systems published from 1998 to 2017. We reviewed titles, abstracts, and full paper contents for evidence of attention to measurement validity, reliability, or reuse. Read More

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http://dx.doi.org/10.1093/jamia/ocz035DOI Listing

Is trigonitis a neglected, imprecise, misunderstood, or forgotten diagnosis?

Low Urin Tract Symptoms 2019 Apr 15. Epub 2019 Apr 15.

Urology Department, UT Southwestern Medical Center, Dallas, Texas.

To consolidate our understanding of "trigonitis" and its relevance in current urologic practice, we reviewed the literature on this entity. The MEDLINE, EMBASE, and Cochrane databases (1905 to present) were systematically reviewed for any English language articles addressing the following terms: trigonitis, cystitis trigoni, cystitis cystica, squamous metaplasia, pseudomembranous trigonitis, vaginal metaplasia, infection or inflammation of the trigone, and trigonitis in recurrent urinary tract infections (rUTI). Abstracts or articles not focused on trigonitis, or those only repeating findings from other original articles on trigonitis, and studies in children or men were excluded. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/luts.12264
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http://dx.doi.org/10.1111/luts.12264DOI Listing
April 2019
2 Reads

BSCR Autumn Meeting Abstracts.

Authors:

Cardiovasc Drugs Ther 2019 Apr 16. Epub 2019 Apr 16.

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http://dx.doi.org/10.1007/s10557-019-06879-9DOI Listing

Rate and Predictors of Publication of Resident Abstracts Presented at Oman Medical Specialty Board Scientific Meetings.

Sultan Qaboos Univ Med J 2018 Nov 28;18(4):e501-e506. Epub 2019 Mar 28.

Nizwa Polyclinic, Directorate of Nursing, Nizwa, Oman.

Objectives: This study aimed to examine the rate and factors associated with the publication of abstracts presented by residents at Oman Medical Specialty Board (OMSB) scientific meetings.

Methods: This retrospective study was performed in February 2018. Two previous national OMSB scientific meetings at which resident abstracts were presented were identified, having taken place in January 2014 and December 2016, respectively. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443282PMC
November 2018

Patient preferences for disease modifying anti-rheumatic drug treatment in rheumatoid arthritis: A systematic review.

J Rheumatol 2019 Apr 15. Epub 2019 Apr 15.

From the Department of Medicine and Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta; Arthritis Research Canada; Centre for Health Evaluation and Outcome Sciences, Providence Health Care, St Paul's Hospital, Vancouver, British Columbia. The work was supported in part by a Canadian Initiative for Outcomes in Rheumatology Care (CIORA) grant. Dr. Hazlewood is supported by a Canadian Institute of Health Research (CIHR) New Investigator Salary Award and The Arthritis Society Young Investigator Salary Award. Dr. Marshall is supported by a CIHR Canada Research Chair in Health Services and Systems Resea. Address correspondence to Dr. Glen Hazlewood, 3330 Hospital Dr NW, Calgary, Alberta, Canada, T2N 4N1 Tel: (403) 220-5903, Fax: (403) 210-7367 Email:

Objective: To summarize patients' preferences for disease modifying anti-rheumatic drug (DMARD) therapy in rheumatoid arthritis (RA).

Methods: We conducted a systematic review to identify English-language studies in adult RA patients that measured patients' preferences for DMARDs or health states and treatment outcomes relevant to DMARD decisions. Study quality was assessed using a published quality assessment tool. Read More

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http://dx.doi.org/10.3899/jrheum.181165DOI Listing
April 2019
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Exploring standardisation, monitoring and training of medical devices in assisted vaginal birth studies: protocol for a systematic review.

BMJ Open 2019 Apr 14;9(4):e028300. Epub 2019 Apr 14.

Centre for Surgical Research, School of Social and Community Medicine, University of Bristol, Bristol, UK.

Introduction: Assisted vaginal birth (AVB) can markedly improve maternal and neonatal outcomes arising from complications in the second stage of labour. Historically, both forceps and ventouse devices have been used to assist birth; however, they are not without risk and are associated with complications, such as cephalohaematoma, retinal haemorrhage and perineal trauma. As new devices are developed to overcome the limitations of existing techniques, it is necessary to establish their efficacy and effectiveness within randomised controlled trials (RCTs). Read More

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http://dx.doi.org/10.1136/bmjopen-2018-028300DOI Listing
April 2019
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Real-world persistence and adherence with oral bisphosphonates for osteoporosis: a systematic review.

BMJ Open 2019 Apr 14;9(4):e027049. Epub 2019 Apr 14.

Department of Health Professions, Manchester Metropolitan University, Manchester, UK.

Objectives: This study examined patient adherence and persistence to oral bisphosphonates for the treatment of osteoporosis in real-world settings.

Methods: A systematic review was completed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Allied and Complementary Medicine Database (AMED), Database of Abstracts of Reviews of Effects (DARE), Health Technology Assessment (HTA) and National Health Service Economic Evaluation Database NHS EED) databases were searched for studies published in English language up to April 2018. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02704
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http://dx.doi.org/10.1136/bmjopen-2018-027049DOI Listing
April 2019
2 Reads

Influence of adjuvant antibiotics on fistula formation following incision and drainage of anorectal abscesses: a systematic review protocol.

Syst Rev 2019 Apr 15;8(1):95. Epub 2019 Apr 15.

Clinical Epidemiology Program, The University of Ottawa, Ottawa, Canada.

Background: Development of fistula-in-ano following incision and drainage (I&D) of anorectal abscesses occurs in over 30% of patients. It is associated with significant patient morbidity and societal cost. The use of antibiotics following drainage is controversial, with randomized controlled trials reporting opposing conclusions regarding their influence on the rate of fistula formation. Read More

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https://systematicreviewsjournal.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/s13643-019-1002-zDOI Listing
April 2019
1 Read

Relative efficacy of interventions in the treatment of second-line non-small cell lung cancer: a systematic review and network meta-analysis.

BMC Cancer 2019 Apr 15;19(1):353. Epub 2019 Apr 15.

Ohio State University Medical Center, Columbus, OH, USA.

Background: Locally advanced or metastatic non-small cell lung cancer (NSCLC) that has progressed after first-line treatment has a poor prognosis. Recent randomized clinical trials (RCTs) have demonstrated survival benefits of alternative treatments to docetaxel. However, information is lacking on which patients benefit the most and what drug or regimen is optimal. Read More

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http://dx.doi.org/10.1186/s12885-019-5569-5DOI Listing
April 2019
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Review of Methodologies for Assessing Sustainable Diets and Potential for Development of Harmonised Indicators.

Int J Environ Res Public Health 2019 Apr 2;16(7). Epub 2019 Apr 2.

School of Health Sciences, College of Health Science, Massey University, Palmerston North 4442, New Zealand.

The underlying values and priorities that drive policy responses depend largely on the constructs that researchers and decision makers select to measure and the metrics used. Despite much recent attention being given to sustainable diets and food systems and to the importance of clearly measuring sustainability to meet targets, to achieve goals, and to appraise dietary and environmental policies, it is not commonly agreed how the different indicators of sustainable diets are assessed. The evidence base for assessment of these indicators are frequently weak, fragmented, and arbitrary. Read More

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https://www.mdpi.com/1660-4601/16/7/1184
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http://dx.doi.org/10.3390/ijerph16071184DOI Listing
April 2019
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Association between perioperative stroke and 30-day mortality in carotid endarterectomy: A meta-analysis.

Clin Neurol Neurosurg 2019 Apr 1;181:44-51. Epub 2019 Apr 1.

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Electronic address:

Objectives: Perioperative stroke is a known complication of carotid endarterectomy (CEA) for patients with symptomatic and asymptomatic carotid stenosis. The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) has shown that stroke following CEA is associated with nearly a 3-fold increase in the 4-year mortality compared to patients without such an event. However, no studies to date can establish whether the stroke was the cause of the short term mortality. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.03.028DOI Listing

Evaluating automated entity extraction with respect to drug and non-drug treatment strategies.

J Biomed Inform 2019 Apr 12:103177. Epub 2019 Apr 12.

School of Information Sciences, University of Illinois at Urbana Champaign.

Objectives: Treatment used in a randomized clinical trial is a critical data element both for physicians at the point of care and reviewers who are evaluating different interventions. Much of existing work on treatment extraction from the biomedical literature has focused on the extraction of pharmacological interventions. However, non-pharmacological interventions (e. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15320464193009
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http://dx.doi.org/10.1016/j.jbi.2019.103177DOI Listing
April 2019
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An Academic Research Coach: An Innovative Approach to Increasing Scholarly Productivity in Medicine.

J Hosp Med 2019 Apr 8;14:E1-E5. Epub 2019 Apr 8.

Department of Medicine, Division of General Internal Medicine, University of Washington, Seattle, Washington.

Background: Academic faculty who devote most of their time to clinical work often struggle to engage in meaningful scholarly work. They may be disadvantaged by limited research training and limited time. Simply providing senior mentors and biostatistical support has limited effectiveness. Read More

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http://dx.doi.org/10.12788/jhm.3194DOI Listing

Evaluation of Biochemical Parameters Present in the Saliva of Patients with Chronic Periodontitis: Results from a Meta-Analysis.

Genet Test Mol Biomarkers 2019 Apr;23(4):255-263

Laboratory of Histological Analysis and Preparation (LAPHIS), Federal University of Piauí, Parnaíba, Brazil.

Aims: Periodontitis results from the presence of periodontopathogenic bacterial activity in the region of the gingival sulcus promoting tissue degradation and alveolar bone resorption. Biochemical analysis of the saliva can be used as a less invasive method for disease prognosis. This study aimed to evaluate the relationship between biochemical protein levels in the saliva sample of patients with chronic periodontitis and healthy patients. Read More

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http://dx.doi.org/10.1089/gtmb.2017.0272DOI Listing

Ghostwriting in biomedicine: a review of the published literature.

Curr Med Res Opin 2019 Apr 15. Epub 2019 Apr 15.

d Janssen Global Services, LLC , Raritan , NJ , USA.

Introduction: The systematic review of biomedical ghostwriting has proven challenging due to problems in consistency and in study design. Moreover, authorship guidelines established by the International Committee of Medical Journal Editors (ICMJE) may have inadvertently created opportunities to potentiate ghostwriting. Given continued interest in ghostwriting by the International Society of Medical Publication Professionals (ISMPP) and other organizations, we undertook an analysis of ghostwriting in the biomedical literature. Read More

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http://dx.doi.org/10.1080/03007995.2019.1608101DOI Listing

The effectiveness and safety of moxibustion for dry eye: Protocol for a systematic review.

Medicine (Baltimore) 2019 Apr;98(15):e15178

Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China.

Background: Dry eye (DE) is a common type of ocular surface disease that affects many people. Moxibustion has been widely used in China to treat ocular surface diseases, especially DE. Many clinical trials have demonstrated that moxibustion can increase the tear secretion quantity and improve tear film stability. Read More

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http://dx.doi.org/10.1097/MD.0000000000015178DOI Listing
April 2019
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