2,922 results match your criteria Abruptio Placentae


Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality.

J Assist Reprod Genet 2018 Oct 17. Epub 2018 Oct 17.

Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Purpose: To evaluate the risk of prematurity and infant mortality by maternal fertility status, and for in vitro fertilization (IVF) pregnancies, by oocyte source and embryo state combinations.

Methods: Women in 14 States who had IVF-conceived live births during 2004-13 were linked to their infant's birth and death certificates; a 10:1 sample of non-IVF births was selected for comparison; those with an indication of infertility treatment on the birth certificate were categorized as subfertile, all others were categorized as fertile. Risks were modeled separately for the fertile/subfertile/IVF (autologous-fresh only) group and for the IVF group by oocyte source-embryo state combinations, using logistic regression, and reported as adjusted odds ratios (AORs) and 95% confidence intervals (CI). Read More

View Article
October 2018
1 Read

Birth Certificate Validity and the Impact on Primary Cesarean Section Quality Measure in New York State.

J Community Health 2018 Oct 15. Epub 2018 Oct 15.

Office of Quality and Patient Safety, New York State Department of Health, Corning Tower, Empire State Plaza, Albany, NY, 12237, USA.

In New York (NY), birth certificate data are routinely used for assessing quality of care and health outcomes such as primary cesarean section (PCS) rates. However rare events are often underreported. This study compared birth certificates to medical records, and examined the impact of underreporting on risk adjustment variables for PCS. Read More

View Article
October 2018
6 Reads

Abruptio Placentae Caused by Hypertriglyceridemia-Induced Acute Pancreatitis during Pregnancy: Case Report and Literature Review.

Case Rep Obstet Gynecol 2018 5;2018:3869695. Epub 2018 Sep 5.

Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul Health Sciences University, Istanbul, Turkey.

Background: Hormonal effects during pregnancy can compromise otherwise controlled lipid levels in women with hypertriglyceridemia and predispose to pancreatitis leading to increased morbidity for mother and fetus. Elevation of triglyceride levels is a risk factor for development of pancreatitis if it exceeds 1000 mg/dL. Pancreatitis should be considered in emergency cases of abdominal pain and uterine contractions in Emergency Department at any stage of pregnancy. Read More

View Article
September 2018
4 Reads

Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study.

Am J Obstet Gynecol 2018 Dec 5;219(6):617.e1-617.e17. Epub 2018 Sep 5.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

Background: Abruptio placentae is a complex multifactorial disease that is associated with maternal and neonatal death and morbidity. Abruptio placentae's high recurrence rate, high prevalence of heritable thrombophilia among women with abruptio placentae, and aggregation of cases in families of women with the disease support the possibility of a genetic predisposition. Previous genome-wide and candidate gene association studies have identified single nucleotide polymorphisms in mitochondrial biogenesis and oxidative phosphorylation genes that potentially are associated with abruptio placentae risk. Read More

View Article
December 2018
4 Reads

Stillbirth rate and causes in a low-resource setting, Mpilo Central Hospital, Bulawayo, Zimbabwe.

Authors:
Solwayo Ngwenya

Trop Doct 2018 Oct 8;48(4):310-313. Epub 2018 Aug 8.

1 Consultant Obstetrician and Gynaecologist, Head of Department of Obstetrics & Gynaecology, Clinical Director, Mpilo Central Hospital, Mzilikazi, Zimbabwe.

A global concern is to end preventable stillbirths by the year 2030. The objective of this study was to document the stillbirth rate and causes of stillbirths in a low-resource setting. This was a retrospective descriptive study carried out at Mpilo Central Hospital, a tertiary teaching referral government hospital in Bulawayo, Zimbabwe during the period January to December 2016. Read More

View Article
October 2018
11 Reads

Placental Chorioangioma with Nonimmune Hydrops Fetalis.

South Med J 2018 08;111(8):457-459

From the Department of Pediatrics, West Virginia University School of Medicine, Charleston, and the Departments of Obstetrics and Gynecology, Pathology, and Pediatrics, Marshall University Joan C. Edwards School of Medicine, Huntington, WV.

A 38-year-old woman was found to have a large placental chorioangioma. The fetus was studied using ultrasound. The pregnancy became complicated by hydrops fetalis, polyhydramnios, and abruptio placenta. Read More

View Article
August 2018
11 Reads

Assesment of pregnancy outcomes among twin pregnancies with single fetal demise regarding chorionicity and fetal death time.

J Turk Ger Gynecol Assoc 2018 07 31. Epub 2018 Jul 31.

Department of Obstetrics and Gynecology, Zeynep Kamil Maternity and Pediatric Research and Training Hospital, İstanbul, Turkey.

Objectives: The objective of this study is to assess maternal and perinatal outcome of twin pregnancies with single fetal demise in terms of chorionicity and fetal death time.

Material And Methods: All the deliveries between January 2008 and July 2015 were reviewed retrospectively and 85 twin pregnancies with single fetal demise were included. These cases were grouped according to chorionicity and fetal death time. Read More

View Article
July 2018
2 Reads

Usefulness of maternal fetal red blood cell count in rhesus-positive pregnant women.

Horm Mol Biol Clin Investig 2018 Jul 31;35(3). Epub 2018 Jul 31.

UZA Antwerp University Hospital, Departement of Gynecology and Obstetrics, Edegem, Belgium.

Background Fetal red blood cells (FRBC) in maternal blood are counted in rhesus-negative women to determine the amount of anti-D immunoglobulin to be administered in the case of a rhesus-positive fetus. In rhesus-positive pregnant women this is done in not always very well-defined indications including trauma, miscarriage, fetal death and diminished fetal movements. The aim of this study is to determine if the detection of FRBC is useful in rhesus-positive pregnant woman. Read More

View Article
July 2018
2 Reads

Effect of homocysteine on pregnancy: A systematic review.

Chem Biol Interact 2018 Sep 24;293:70-76. Epub 2018 Jul 24.

West-Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan.

Research purpose was to put together the available pieces of present scientific data and to close the gap in the knowledge of Hcy levels in pregnancy and its association with some pregnancy complications. Scientific data were taken from research papers published between January 1990 and December 2017, and found on the Internet (PubMed, ClinicalKey and Embase databases) by the following tags entered in English, Russian, French and German languages: pregnancy, homocysteine, pregnancy complications, pregnancy loss, preeclampsia, intrauterine growth restriction, and placental abruption. The review showed that Hcy levels range in uncomplicated pregnancy. Read More

View Article
September 2018
1 Read

Tracking stillbirths by referral pattern and causes in a rural tertiary hospital in Southern Nigeria.

Niger Postgrad Med J 2018 Apr-Jun;25(2):87-93

Department of Obstetrics and Gynaecology, Madonna University Teaching Hospital, Rivers State, Nigeria.

Background: The burden of stillbirth is disproportionately more in rural areas of developing countries where unskilled birth attendants contribute a large quota in the management of pregnant women. Tracking stillbirth should include the pattern of referral from the primary institutions that take care of these women.

Aims And Objectives: This study evaluated the causes and determinants of stillbirth by the referral pattern in a rural area in southern Nigeria. Read More

View Article
July 2018
5 Reads

Placental abruption: etiopathogenic aspects, diagnostic and therapeutic implications.

Rom J Morphol Embryol 2018 ;59(1):187-195

Department of Obstetrics and Gynecology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; Department of Family Medicine, Faculty of Midwifery and Nursing, University of Medicine and Pharmacy of Craiova, Romania;

The severe form of retroplacental hematoma is a serious accident in the second stage of pregnancy and at birth with frightening for the mother and fetus that often lead to death. The pathological mechanism presumes conditions for a "special ground" capital for the "efficiency" of the acute intradecidual vascular accident with the rupture of the uterus-placental arterioles. The complete clinical picture of this severe form of retroplacental hematoma - the placental abruption, observed and mentioned by the classics (vascular drama of Couvelaire) consists of five syndromes, 18 signs and symptoms, four paradoxes, phenomena not fully met in the other forms of retroplacental hematoma (minor and intermediate). Read More

View Article
October 2018
1 Read

Maternal, fetal, and neonatal outcomes among different types of hypertensive disorders associating pregnancy needing intensive care management.

J Matern Fetal Neonatal Med 2018 Sep 9:1-8. Epub 2018 Sep 9.

c Obstetrics and Gynecology Department , Fayoum University , Fayoum , Egypt.

Objective: To assess the relationship between maternal, fetal, and neonatal outcomes and different forms of hypertensive disorders associating pregnancy in women needed intensive care units (ICUs) admission.

Methods: A prospective case control study was conducted on 1238 women admitted to hypertensive ICU at three university hospitals. They were classified into four groups. Read More

View Article
September 2018
14 Reads

Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies.

Placenta 2018 Jun 16;66:8-16. Epub 2018 Apr 16.

Center for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA.

Introduction: Accumulating epidemiological evidence points to strong genetic susceptibility to placental abruption (PA). However, characterization of genes associated with PA remains incomplete. We conducted a genome-wide association study (GWAS) of PA and a meta-analysis of GWAS. Read More

View Article
June 2018
4 Reads

Effect of twin pregnancy chorionic properties on maternal and fetal outcomes.

Taiwan J Obstet Gynecol 2018 Jun;57(3):351-354

Department of Obstetrics and Gynecology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.

Objective: This study aimed to determine the effect of twin pregnancy chorionic properties on pregnancy complications and fetal outcomes.

Materials And Methods: A total of 559 subjects with gemellary pregnancy were included in the retrospective analysis, and clinical data, such as monitoring data during pregnancy and maternal and fetal outcomes, were recorded in detail. Based on the ultrasound results and methods of the postpartum pathologic examination of the placental membranes, the subjects were divided into the twin group with monochorionic diamnion (MCDA group, n = 198) and twin group with dichorionic diamnion (DCDA group, n = 361). Read More

View Article
June 2018
5 Reads

The effect of advanced maternal age on maternal and neonatal outcomes of placenta previa: A register-based cohort study.

Eur J Obstet Gynecol Reprod Biol 2018 Aug 19;227:1-7. Epub 2018 May 19.

Department of Obstetrics and Gynecology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.

Objectives: Advanced maternal age (AMA) at the time of delivery generally worsens obstetric outcomes, but its effects on specific pregnancy problems, such as placenta previa, have not been adequately assessed. Therefore, the objective of the study was to explore the effect of AMA on adverse maternal and neonatal outcomes among pregnancies complicated by placenta previa.

Study Design: The study was a register-based cohort study using data of three Finnish health registries, including information of 283 324 women and their newborns. Read More

View Article
August 2018
3 Reads

Determinants of infant mortality for children of women prisoners: a longitudinal linked data study.

BMC Pregnancy Childbirth 2018 Jun 1;18(1):202. Epub 2018 Jun 1.

Health Economics and Social Policy Group, Centre for Population Health Research, Sansom Institute, School of Health Sciences, University of South Australia, GPO Box 2471, Adelaide, SA, 5001, Australia.

Background: There is limited information on the determinants of infant mortality outcomes for the children of women prisoners. This study aimed to explore determinants of infant mortality for Indigenous and non-Indigenous children, with a specific focus on maternal imprisonment during pregnancy as a risk factor.

Methods: Using linked administrative data we obtained a longitudinal sample of 42,674 infants born in Western Australia between October 1985 and June 2013. Read More

View Article

Prenatal predictors of neonatal intensive care unit admission due to respiratory distress.

Pediatr Int 2018 Jun;60(6):560-564

Department of Neonatal Intensive Care Unit, Nara Prefecture General Medical Center, Nara, Japan.

Background: Admission to the neonatal intensive care unit (NICU) due to respiratory distress is determined according to subjective clinician judgement. We investigated prenatal factors predictive of NICU admission in neonates with respiratory distress.

Methods: This case-control study was conducted at Nara Prefecture General Medical Center, Nara, Japan, from February 2013 to April 2017 and included neonates with birthweight ≥2,000 g, ≥36 weeks of gestational age, who required oxygen due to respiratory distress at birth. Read More

View Article
June 2018
2 Reads

Ultrasonographic prediction of antepartum deterioration of growth-restricted fetuses after late preterm.

J Obstet Gynaecol Res 2018 Jun 2;44(6):1057-1062. Epub 2018 Apr 2.

Department of Maternal Fetal Medicine, Osaka Medical Center Research Institute for Maternal and Child Health, Osaka, Japan.

Aim: To examine the predictive value of ultrasound parameters for antepartum non-reassuring fetal status (NRFS) in fetal growth restriction (FGR) cases after late preterm.

Methods: Retrospective review of singleton FGR cases before 37 weeks gestation who delivered after 34 weeks gestation was performed. The association between ultrasound parameters that was assessed from 34 to 36 weeks gestation and the development of antepartum NRFS that was diagnosed by nonstress test and biophysical profile was analyzed by using multivariate Cox proportional hazards analyses. Read More

View Article
June 2018
2 Reads

Labor induction versus expectant management at early term in pregnancies with second trimester elevated human chorionic gonadotropin or alpha fetoprotein.

J Obstet Gynaecol Res 2018 Jun 8;44(6):1049-1056. Epub 2018 Mar 8.

Department of Obstetrics and Gynecology, Emek Medical Center, Afula, Israel.

Aim: Elevated human chorionic gonadotropin (HCG) and alpha fetoprotein (AFP) have been linked to placental dysfunction and associated morbidities. We aimed to compare the induction of labor with expectant management at term in those pregnancies for the prevention of neonatal and maternal morbidities.

Methods: Women with second trimester HCG ≥ 2 and/or AFP ≥ 2 multiples of the median, without additional maternal or fetal complications, from their 38th gestational week were offered the choice of labor induction or expectant management. Read More

View Article
June 2018
5 Reads

Placental abruption after amnioreduction for polyhydramnios caused by chorioangioma.

BMJ Case Rep 2018 Mar 5;2018. Epub 2018 Mar 5.

Department of Obstetrics and Gynecology, Harbor UCLA Medical Center, Torrance, California, USA.

Placental chorioangioma is the most common type of a benign placental tumour that occurs in 1% of pregnancies. A large chorioangioma is associated with adverse pregnancy outcomes. We present a case of placental abruption necessitating preterm delivery after multiple amnioreductions for polyhydramnios caused by a large chorioangioma. Read More

View Article
March 2018
5 Reads

Size of uterine leiomyoma is a predictor for massive haemorrhage during caesarean delivery.

Eur J Obstet Gynecol Reprod Biol 2018 Apr 21;223:60-63. Epub 2018 Feb 21.

Department of Obstetrics and Gynecology, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan.

Background: Uterine leiomyoma is a common benign tumour, and a risk factor for various complications during pregnancy and peripartum period. Peripartum haemorrhage is the most critical complication that can cause maternal death. Although the relationship of leiomyoma and peripartum haemorrhage has been indicated, little is known about the characteristics of leiomyoma as predictors for massive haemorrhage in caesarean delivery. Read More

View Article
April 2018
2 Reads

Advanced maternal age and its association with placenta praevia and placental abruption: a meta-analysis.

Cad Saude Publica 2018 Feb 19;34(2):e00206116. Epub 2018 Feb 19.

Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.

This study aimed to investigate the existence and magnitude of the association between advanced maternal age (AMA) and occurrence of placenta praevia (PP) and placental abruption (PA) among nulliparous and multiparous women, by a systematic review and meta-analysis. We searched articles published between January 1, 2005 and December 31, 2015, in any language, in the following databases: PubMed, Scopus, Web of Science, and LILACS. Women were grouped into two age categories: up to 34 years old and 35 years or older. Read More

View Article
February 2018
2 Reads

Unique fluid-fluid level ultrasonic appearance in subacute placenta abruption with massive subchorionic hematoma.

Int J Gynaecol Obstet 2018 06 13;141(3):391-392. Epub 2018 Mar 13.

Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

View Article
June 2018
5 Reads

Relevant obstetric factors associated with fetal heart rate monitoring for cerebral palsy in pregnant women with hypertensive disorder of pregnancy.

J Obstet Gynaecol Res 2018 Apr 23;44(4):647-654. Epub 2018 Jan 23.

University of Miyazaki, Miyazaki, Japan.

Aim: The study identifies the relevant obstetric factors associated with fetal heart rate (FHR) monitoring for cerebral palsy (CP) in pregnant women with hypertensive disorders of pregnancy (HDP).

Methods: The subjects were neonates with CP (birth weight ≥ 2000 g, gestational age ≥ 33 weeks) who were approved for compensation for CP by the Operating Organization of the Japan Obstetric Compensation System between 2009 and 2012. After selection of women with antepartum HDP, obstetric characteristics associated with FHR monitoring were analyzed. Read More

View Article
April 2018
3 Reads
0.930 Impact Factor

Caesarean delivery-related blood transfusion: correlates in a tertiary hospital in Southwest Nigeria.

BMC Pregnancy Childbirth 2018 01 10;18(1):24. Epub 2018 Jan 10.

Department of Obstetrics and Gynaecology, Lagos State University College of Medicine/Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.

Background: Caesarean delivery carries a risk of major intra-operative blood loss and its performance is often delayed by non-availability of blood and blood products. Unnecessary cross-matching and reservation of blood lead to apparent scarcity in centres with limited supply. This study set out to identify the risk factors for blood transfusion in women who underwent caesarean delivery at a tertiary obstetric unit with a view to ensuring efficient blood utilization. Read More

View Article
January 2018
7 Reads

Meta-analysis on the effect of aspirin use for prevention of preeclampsia on placental abruption and antepartum hemorrhage.

Am J Obstet Gynecol 2018 05 3;218(5):483-489. Epub 2018 Jan 3.

Harris Birthright Research Centre of Fetal Medicine, Fetal Medicine Research Institute, King's College Hospital, London, UK.

Objective Data: Impaired placentation in the first 16 weeks of pregnancy is associated with increased risk of subsequent development of preeclampsia, birth of small-for-gestational-age neonates, and placental abruption. Previous studies reported that prophylactic use of aspirin reduces the risk of preeclampsia and small-for-gestational-age neonates with no significant effect on placental abruption. However, meta-analyses of randomized controlled trials that examined the effect of aspirin in relation to gestational age at onset of therapy and dosage of the drug reported that significant reduction in the risk of preeclampsia and small-for-gestational-age neonates is achieved only if the onset of treatment is at ≤16 weeks of gestation and the daily dosage of the drug is ≥100 mg. Read More

View Article
May 2018
35 Reads

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 - 2014; a descriptive study.

BMC Pregnancy Childbirth 2018 01 4;18(1). Epub 2018 Jan 4.

The National Perinatal Epidemiology Centre, University College Cork, Cork, Ireland.

Background: Intrapartum fetal death, the death of a fetus during labour, is a tragic outcome of pregnancy. The intrapartum death rate of a country is reflective of the care received by mothers and babies in labour and it is through analysing these cases that good aspects of care, as well as areas for improvement can be identified. Investigating unexpected neonatal deaths that may be associated with an intrapartum event is also helpful to fully appraise intrapartum care. Read More

View Article
January 2018
3 Reads

ACOG Practice Bulletin No. 188: Prelabor Rupture of Membranes.

Authors:

Obstet Gynecol 2018 01;131(1):e1-e14

Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (1, 2). Preterm prelabor rupture of membranes (also referred to as premature rupture of membranes) (PROM) complicates approximately 3% of all pregnancies in the United States (3). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Read More

View Article
January 2018
9 Reads

ACOG Practice Bulletin No. 188 Summary: Prelabor Rupture of Membranes.

Authors:

Obstet Gynecol 2018 01;131(1):187-189

Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (1, 2). Preterm prelabor rupture of membranes (also referred to as premature rupture of membranes) (PROM) complicates approximately 3% of all pregnancies in the United States (3). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Read More

View Article
January 2018
6 Reads

Auditing stillbirths at Lower Umfolozi War Memorial Regional Hospital: A 12-month review.

Authors:
I Govender

S Afr Med J 2017 Nov 27;107(12):1121-1126. Epub 2017 Nov 27.

KwaZulu-Natal Department of Health, Lower Umfolozi War Memorial Regional Hospital, Empangeni, South Africa.

Background: Although the total number of stillbirths worldwide was estimated at 2.6 million in 2009, there is currently a dearth of literature on stillbirths in developing countries and rural settings, where the majority of such births occur. The 'Hands Up' Mortality and Morbidity Extraction Tool (HUMMET), developed at Lower Umfolozi War Memorial Regional Hospital (LUWMRH) in 2010, outlines a systematic approach to summarising individual cases of adverse perinatal outcomes. Read More

View Article
November 2017
7 Reads

[Risk Factors for Blood Transfusion in Women with Postpartum Hemorrhage: a Case-control Study].

Sichuan Da Xue Xue Bao Yi Xue Ban 2017 Nov;48(6):937-940

Department of Obstetrics and Gynecology,West China Second University Hospital,Sichuan University,Chengdu 610041,China.

Objective: To investigate the risk factors for increased red blood cells (RBCs) transfusion ratio in the women with postpartum hemorrhage (PPH).

Methods: This case-control study obtained the inpatient medical records of 112 441 pregnant women from 37 hospitals in 2011. There were 4 131 women diagnosed with PPH,record data of those patients were analyzed,including basic characteristics of patients,the level of hospital,pregnancy related complications,prenatal hemoglobin (Hb),mode of delivery,details of postpartum blood loss and blood transfusion,and maternal and neonatal outcomes. Read More

View Article
November 2017
13 Reads

Lessons Learned from 78 Long Days in the NICU.

Authors:
Alaina Pyle

Narrat Inq Bioeth 2017 ;7(3):192-194

View Article
December 2018

Placental abruption leading to hysterectomy.

BMJ Case Rep 2017 Dec 11;2017. Epub 2017 Dec 11.

Department of Obstetrics and Gynaecology, King Edward Memorial Hospital, Subiaco, Western Australia, Australia.

A 32-year-old multigravid patient at 21 weeks gestation presents with major concealed placental abruption and subsequent fetal demise. During an eventually failed misoprostol regime aiming for vaginal delivery she develops severe disseminated intravascular coagulopathy. Subsequent hysterotomy reveals Couvelaire uterus with major haemorrhage and requires subtotal hysterectomy for haemostasis. Read More

View Article
December 2017

Placental Abruption With Delayed Fetal Compromise in Maternal Acetaminophen Toxicity.

Obstet Gynecol 2017 12;130(6):1385

Department of OB/GYN, Albany Medical College, Albany, New York Division of Maternal Fetal Medicine, Albany Medical College, Albany, New York.

View Article
December 2017
29 Reads

Heat and pregnancy-related emergencies: Risk of placental abruption during hot weather.

Environ Int 2018 02 14;111:295-300. Epub 2017 Nov 14.

University of Montreal Hospital Research Centre, 900 Saint Denis St, Montreal, Quebec H2X 0A9, Canada; Institut national de santé publique du Québec, 190 Cremazie Blvd E, Montreal, Quebec H2P 1E2, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1020 Pine Avenue W, Montreal, Quebec H3A 1A2, Canada; School of Public Health, University of Montreal, 7101 Parc Avenue, Montreal, Quebec H3N 1X9, Canada. Electronic address:

Introduction: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. Read More

View Article
February 2018
4 Reads

Placental Complications Associated With Psychostimulant Use in Pregnancy.

Obstet Gynecol 2017 12;130(6):1192-1201

Department of Epidemiology, Harvard T.H. Chan School of Public Health, the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, and the Department of Anesthesiology, Brigham and Women's Hospital and Harvard Medical School, and the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

Objective: To evaluate whether psychostimulants used to treat attention-deficit/hyperactivity disorder (ADHD) are associated with risk of adverse placental-associated pregnancy outcomes including preeclampsia, placental abruption, growth restriction, and preterm birth.

Methods: We designed a population-based cohort study in which we examined a cohort of pregnant women and their liveborn neonates enrolled in Medicaid from 2000 to 2010. Women who received amphetamine-dextroamphetamine or methylphenidate monotherapy in the first half of pregnancy were compared with unexposed women. Read More

View Article
December 2017
26 Reads

Society for Maternal-Fetal Medicine (SMFM) Consult Series #44: Management of bleeding in the late preterm period.

Am J Obstet Gynecol 2018 01 25;218(1):B2-B8. Epub 2017 Oct 25.

Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA.

Third-trimester bleeding is a common complication arising from a variety of etiologies, some of which may initially present in the late preterm period. Previous management recommendations have not been specific to this gestational age window, which carries a potentially lower threshold for delivery. The purpose of this document is to provide guidance on management of late preterm (34 0/7-36 6/7 weeks of gestation) vaginal bleeding. Read More

View Article
January 2018
20 Reads

Prediction of adverse pregnancy outcomes by extreme values of first trimester screening markers.

Obstet Med 2017 Sep 16;10(3):132-137. Epub 2017 May 16.

Department of Obstetrics and Gynecology, Alto Minho Local Healthcare Unit, Viana do Castelo, Portugal.

Background: To determine the association between extreme values of first trimester markers and adverse pregnancy outcomes.

Methods: A retrospective cohort study of 916 women who underwent first-trimester combined screening during 2015 was performed. Extreme values of NT, pregnancy-associated plasma protein-A (PAPP-A) and free β-hCG, and their association with adverse pregnancy outcomes were analyzed. Read More

View Article
September 2017
5 Reads

An increase in rates of obstetric haemorrhage in a setting of high HIV seroprevalence.

S Afr Med J 2017 Jun 30;107(7):602-605. Epub 2017 Jun 30.

Department of Obstetrics and Gynaecology, Nelson R Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Background: Obstetric haemorrhage (OH) is the leading cause of maternal mortality worldwide, although, indirectly, HIV is also a leading cause of maternal mortality in some settings with a high HIV seroprevalence.

Objective: To determine the possible association between increasing rates of OH and HIV or its treatment.

Methods: We conducted a retrospective chart review of women with OH at King Edward VIII Hospital, Durban, South Africa, over a 3-year period (2009 - 2011), during which the drug regimen for the prevention of mother-to-child transmission was evolving from single-dose nevirapine to antenatal zidovudine combined with intrapartum nevirapine (also referred to as dual therapy), and finally to a combination or highly active antiretroviral therapy (cART or HAART). Read More

View Article
June 2017
12 Reads

Pregnancy Outcomes Among Deaf Women in Washington State, 1987-2012.

Obstet Gynecol 2017 11;130(5):953-960

Department of Epidemiology, School of Public Health, and the Departments of Obstetrics and Gynecology and Rehabilitation Medicine, School of Medicine, University of Washington, and the Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

Objective: To evaluate pregnancy and neonatal outcomes among deaf women using population-based vital records data in Washington State from 1987 to 2012.

Methods: We performed a retrospective cohort study using the Washington State birth and fetal death records linked to state hospital discharge records to identify women with diagnosis codes for deafness indicated at their delivery hospitalization and compared them with randomly selected women without these codes. Pregnancy conditions and outcomes evaluated included gestational diabetes, preeclampsia, placental abruption, labor induction, and cesarean delivery. Read More

View Article
November 2017
18 Reads

Abruptio Placentae with Type II Respiratory Failure Secondary to Acute Interstitial Pneumonia Responsive to Steroids.

J Coll Physicians Surg Pak 2017 Sep;27(9):S106-S107

Department of Critical Care, Patel Hospital, Karachi.

Acute Interstitial Pneumonia (AIP) is categorized as Idiopathic Interstitial Pneumonia (IIP), in which the cause is unknown. Ayoung female of 22 years presented in 34 weeks gestation with abruptio placentae (AP) and underwent Lower Segment Caesarian Section (LSCS) for AP. It progressed to type II respiratory failure secondary to AIPon 4th day post-surgery. Read More

View Article
September 2017
2 Reads

Mortality and causes of death among women with a history of placental abruption.

Acta Obstet Gynecol Scand 2017 Nov 19;96(11):1315-1321. Epub 2017 Sep 19.

Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Introduction: Women with a history of placental abruption have an increased later morbidity, but not much is known of the later mortality.

Material And Methods: Data on women with placental abruption (index cohort) between 1969 and 2005 (n = 7805) were collected from the Finnish Hospital Discharge Register and the Finnish Medical Birth Register. A matched reference cohort consisted of women without placental abruption (n = 23 523). Read More

View Article
November 2017
8 Reads

The histologic evolution of revealed, acute abruptions.

Hum Pathol 2017 09 18;67:187-197. Epub 2017 Aug 18.

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114. Electronic address:

There is considerable interest in using pathology to confirm acute abruptions. It has been suggested that pathologic findings can help to determine the timing of abruptions. Because of the dearth of evidence in the literature supporting this claim and its medicolegal implications, we undertook this study to explore further the possibility of timing abruptions by histopathology. Read More

View Article
September 2017
4 Reads

Maternal and fetal risk factors for stillbirth in Northern Tanzania: A registry-based retrospective cohort study.

PLoS One 2017 15;12(8):e0182250. Epub 2017 Aug 15.

Department of Community Health, Institute of Public Health, Kilimanjaro Christian Medical College, Moshi, Tanzania.

Background: Stillbirth is a major cause of perinatal mortality and occurs disproportionately in developing countries including Tanzania. However, there is scant information regarding the predictors of this condition in Tanzania. This study aimed to determine maternal and fetal risk factors for stilbirth in northen Tanzania. Read More

View Article
October 2017
21 Reads

Intrauterine fetal death caused by seatbelt injury.

Taiwan J Obstet Gynecol 2017 Aug;56(4):558-560

Department of Obstetrics and Gynecology, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji-cho, Fukui 910-1193, Japan.

Objective: Severe motor vehicle accidents involving pregnant women can result in fetal and neonatal death. We describe a case in which fetal death occurred due to relatively mild seatbelt injuries and present the characteristic magnetic resonance imaging (MRI) findings of the placenta.

Case Report: A 26-year-old primigravid woman at 20 weeks gestation was involved in an automobile accident. Read More

View Article
August 2017
5 Reads

Factors contributing to adverse maternal outcomes in patients with HELLP syndrome.

J Matern Fetal Neonatal Med 2018 Nov 8;31(21):2870-2876. Epub 2017 Aug 8.

b Zekai Tahir Women's Health Education and Research Hospital, Obstetrics and Gynecology Perinatology Clinic , Ankara , Turkey.

Objective: To determine the prognostic factors for adverse maternal outcomes in women with complete HELLP syndrome.

Methods: A retrospective cohort study was carried out by searching the hospital data for the diagnosis of HELLP syndrome according to Tennessee classification from January 2007 to January 2014. Data included a total of 171 patients between January 2007 and January 2014. Read More

View Article
November 2018
25 Reads

Placenta Percreta in a Gravid Bicornuate Unicollis Uterus.

Case Rep Obstet Gynecol 2017 11;2017:4082182. Epub 2017 Jun 11.

University of Nairobi, Nairobi, Kenya.

Background: Identifying bicornuate uterus can be challenging especially as a cause of early pregnancy bleeding. On ultrasonographic examination, it is difficult to misdiagnose pregnancy in a bicornuate uterus as an ectopic pregnancy due to the continuity of the endometrium. A rudimentary horn of a bicornuate uterus in early pregnancy can occasionally be misdiagnosed for an ectopic pregnancy especially when compounded by severe abdominal pains and supportive sonographic evidence. Read More

View Article
June 2017
5 Reads

Low expression of soluble human leukocyte antigen G in early gestation and subsequent placenta-mediated complications of pregnancy.

J Obstet Gynaecol Res 2017 Sep 10;43(9):1391-1396. Epub 2017 Jul 10.

Department of Surgical Sciences, Obstetrics and Gynecology, University of Turin, Sant'Anna University Hospital, Turin, Italy.

Aim: Abnormal placentation is a common pathogenic mechanism of many placenta-mediated complications of late pregnancy, including pre-eclampsia, fetal growth restriction, stillbirth, and placental abruption. During successful placentation, the trophoblast (which is a semi-allograft) is not rejected by decidual immune cells because of maternal immune tolerance, mainly induced by human leukocyte antigen G (HLA-G). Deficient HLA-G expression seems to be associated with the development of complications of pregnancy. Read More

View Article
September 2017
6 Reads

An update on the risk factors for and management of obstetric haemorrhage.

Womens Health (Lond) 2017 08 6;13(2):34-40. Epub 2017 Jul 6.

St George's University Hospitals NHS Foundation Trust, London, UK.

Obstetric haemorrhage is associated with increased risk of serious maternal morbidity and mortality. Postpartum haemorrhage is the commonest form of obstetric haemorrhage, and worldwide, a woman dies due to massive postpartum haemorrhage approximately every 4 min. In addition, many experience serious morbidity such as multi-organ failure, complications of multiple blood transfusions, peripartum hysterectomy and unintended damage to pelvic organs, loss of fertility and psychological sequelae, including posttraumatic stress disorders. Read More

View Article
August 2017
50 Reads