2,828 results match your criteria Abruptio Placentae


Hypoproteinemia as a parameter of poor perinatal/neonatal outcomes in women with preeclampsia diagnosed as hypertension plus proteinuria.

Pregnancy Hypertens 2020 May 29;21:111-117. Epub 2020 May 29.

Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Objectives: To investigate the relationship between serum total protein (TP) levels and maternal/neonatal outcomes among pregnant women with preeclampsia.

Study Design: TP was measured at preeclampsia diagnosis and delivery in 94 women with singleton pregnancies and preeclampsia as hypertension with proteinuria who delivered at ≥ 22 gestational weeks (GWs). As a control group, measurements were also made in 188 women with singleton pregnancies without hypertension and/or proteinuria. Read More

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http://dx.doi.org/10.1016/j.preghy.2020.05.012DOI Listing

A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia.

Obstet Gynecol Sci 2020 May 3;63(3):270-277. Epub 2020 Apr 3.

Department of Neonatology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Objective: The risk factors, clinical trends, and maternal and fetal health of early- and late-onset preeclampsia have not been adequately studied. We examined the effects of early- and late-onset preeclampsia on maternal and perinatal outcomes as well as the known risk factors of preeclampsia.

Methods: One hundred and fifty women with preeclampsia were consecutively enrolled in each group. Read More

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http://dx.doi.org/10.5468/ogs.2020.63.3.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231936PMC

Term complications and subsequent risk of preterm birth: registry based study.

BMJ 2020 04 29;369:m1007. Epub 2020 Apr 29.

National Institute of Environmental Health Sciences, Durham, NC, USA.

Objective: To explore conditions and outcomes of a first delivery at term that might predict later preterm birth.

Design: Population based, prospective register based study.

Setting: Medical Birth Registry of Norway, 1999-2015. Read More

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http://dx.doi.org/10.1136/bmj.m1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188013PMC

Tobacco and Nicotine Cessation During Pregnancy: ACOG Committee Opinion, Number 807.

Authors:

Obstet Gynecol 2020 May;135(5):e221-e229

Pregnant women should be advised of the significant perinatal risks associated with tobacco use, including orofacial clefts, fetal growth restriction, placenta previa, abruptio placentae, preterm prelabor rupture of membranes, low birth weight, increased perinatal mortality, ectopic pregnancy, and decreased maternal thyroid function. Children born to women who smoke during pregnancy are at an increased risk of respiratory infections, asthma, infantile colic, bone fractures, and childhood obesity. Pregnancy influences many women to stop smoking, and approximately 54% of women who smoke before pregnancy quit smoking directly before or during pregnancy. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003822DOI Listing

Tobacco and Nicotine Cessation During Pregnancy: ACOG Committee Opinion Summary, Number 807.

Authors:

Obstet Gynecol 2020 May;135(5):1244-1246

Pregnant women should be advised of the significant perinatal risks associated with tobacco use, including orofacial clefts, fetal growth restriction, placenta previa, abruptio placentae, preterm prelabor rupture of membranes, low birth weight, increased perinatal mortality, ectopic pregnancy, and decreased maternal thyroid function. Children born to women who smoke during pregnancy are at an increased risk of respiratory infections, asthma, infantile colic, bone fractures, and childhood obesity. Pregnancy influences many women to stop smoking, and approximately 54% of women who smoke before pregnancy quit smoking directly before or during pregnancy. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003825DOI Listing

Perinatal outcomes of cesarean deliveries in Sierra Leone: A prospective multicenter observational study.

Int J Gynaecol Obstet 2020 Apr 19. Epub 2020 Apr 19.

Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Objective: To analyze the indications for cesarean deliveries and factors associated with adverse perinatal outcomes in Sierra Leone.

Methods: Between October 2016 and May 2017, patients undergoing cesarean delivery performed by medical doctors and associate clinicians in nine hospitals were included in a prospective observational study. Data were collected perioperatively, at discharge, and during home visits after 30 days. Read More

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http://dx.doi.org/10.1002/ijgo.13172DOI Listing

Hemodynamic changes after spinal anesthesia in preeclamptic patients undergoing cesarean section at a tertiary referral center in Ethiopia: a prospective cohort study.

Patient Saf Surg 2020 31;14. Epub 2020 Mar 31.

2Department of anesthesia, Univesity of Gondar, Gondar, Ethiopia.

Background: Spinal anesthesia-induced maternal hypotension is the most frequent complication associated with maternal morbidity and mortality during Cesarean section. The aim of this study was to compare the incidence and magnitude of hemodynamic changes in preeclamptic and non-preeclamptic parturients undergone Cesarean section under spinal anesthesia.

Method: A prospective cohort study was conducted from 01 February to 28 May 2019 in preeclamptic and non-preeclamptic parturients. Read More

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http://dx.doi.org/10.1186/s13037-020-00234-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110765PMC

Alcohol and Psychoactive Drugs in Pregnancy.

Maedica (Buchar) 2019 Dec;14(4):397-401

Filantropia Hospital, Department of obstetrics and Gynecology, Bucharest, Romania.

Although often difficult to diagnose, the use of psychoactive drugs during pregnancy has become a commonly encountered occurrence. The present article aims to clarify the effects of alcohol, tobacco, narcotics, antidepressants, stimulants, halucinogenes and canabioids consumption on pregnancy and the newborn. There are differences within the types of drugs consumption: use/abuse/addiction of psychoactive medication during pregnancy. Read More

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http://dx.doi.org/10.26574/maedica.2019.14.4.397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035437PMC
December 2019

Prelabor Rupture of Membranes: ACOG Practice Bulletin, Number 217.

Authors:

Obstet Gynecol 2020 Mar;135(3):e80-e97

Preterm birth occurs in approximately 10% of all births in the United States and is a major contributor to perinatal morbidity and mortality (). Prelabor rupture of membranes (PROM) that occurs preterm complicates approximately 2-3% of all pregnancies in the United States, representing a significant proportion of preterm births, whereas term PROM occurs in approximately 8% of pregnancies (). The optimal approach to assessment and treatment of women with term and preterm PROM remains challenging. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003700DOI Listing

Prelabor Rupture of Membranes: ACOG Practice Bulletin Summary, Number 217.

Authors:

Obstet Gynecol 2020 Mar;135(3):739-743

Preterm birth occurs in approximately 10% of all births in the United States and is a major contributor to perinatal morbidity and mortality (). Prelabor rupture of membranes (PROM) that occurs preterm complicates approximately 2-3% of all pregnancies in the United States, representing a significant proportion of preterm births, whereas term PROM occurs in approximately 8% of pregnancies (). The optimal approach to assessment and treatment of women with term and preterm PROM remains challenging. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003701DOI Listing

Nonfetal Imaging During Pregnancy: Placental Disease.

Radiol Clin North Am 2020 Mar;58(2):381-399

Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA, USA.

Placenta is a vital organ that connects the maternal and fetal circulations, allowing exchange of nutrients and gases between the two. In addition to the fetus, placenta is a key component to evaluate during any imaging performed during pregnancy. The most common disease processes involving the placenta include placenta accreta spectrum disorders and placental masses. Read More

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http://dx.doi.org/10.1016/j.rcl.2019.11.004DOI Listing

Prolonged neuromuscular blockade and insufficient reversal after sugammadex administration in cesarean section under general anesthesia: a case report.

JA Clin Rep 2019 Apr 11;5(1):28. Epub 2019 Apr 11.

Department of Anesthesia, Japan Community Health Care Organization, Kyushu Hospital, 1-8-1 Kishinoura, Yahatanishi-ku, Kitakyushu City, Fukuoka, 806-8501, Japan.

Background: We present a rare case of prolonged neuromuscular blockade and insufficient reversal after sugammadex administration in a pregnant patient being treated with magnesium sulfate and nifedipine undergoing cesarean section under general anesthesia.

Case Presentation: A 37-year-old woman at 34 weeks gestation, weighing 42.5 kg, and receiving magnesium sulfate 94 mg/kg for preeclampsia and nifedipine 20 mg, underwent cesarean section under general anesthesia for abruptio placentae. Read More

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http://dx.doi.org/10.1186/s40981-019-0248-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966907PMC

Correlations of placental abruption with other complications of pregnant women and inflammatory factors in amniotic fluid.

Authors:
H Zhang M Li

J Biol Regul Homeost Agents 2019 Nov-Dec;33(6):1755-1763

Department of Reproductive Center, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

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http://dx.doi.org/10.23812/19-258-LDOI Listing
February 2020

Thrombin-Induced Decidual Colony-Stimulating Factor-2 Promotes Abruption-Related Preterm Birth by Weakening Fetal Membranes.

Am J Pathol 2020 02;190(2):388-399

Department of Obstetrics and Gynecology, University of South Florida, Morsani College of Medicine, Tampa, Florida. Electronic address:

Preterm premature rupture of membranes (PPROM) and thrombin generation by decidual cell-expressed tissue factor often accompany abruptions. Underlying mechanisms remain unclear. We hypothesized that thrombin-induced colony-stimulating factor-2 (CSF-2) in decidual cells triggers paracrine signaling via its receptor (CSF2R) in trophoblasts, promoting fetal membrane weakening and abruption-associated PPROM. Read More

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http://dx.doi.org/10.1016/j.ajpath.2019.10.020DOI Listing
February 2020

Uterine rupture during pregnancy.

Ceska Gynekol 2019 ;84(5):345-350

Objective: A review of contemporary knowledge about uterine rupture during pregnancy, followed by a case-report of a patient with uterine rupture during pregnancy without an uterine scar.

Design: Review and case report.

Setting: Clinic of Obstetrics and Gynecology, University Hospital, Hradec Králové; Department of Gynecology and Obstetrics, Hospital Náchod. Read More

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December 2019

Massive Severe Uteroplacental and Uteropelvic Apoplexy.

Z Geburtshilfe Neonatol 2019 Dec 4;223(6):395-396. Epub 2019 Dec 4.

Ob/Gyn, University Hospital "Sveti Duh", Zagreb, Croatia.

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http://dx.doi.org/10.1055/a-0967-0073DOI Listing
December 2019

[Perinatal Emergencies in Emergency Medical Aid - Obstetric Emergencies Series, Part 4].

Z Geburtshilfe Neonatol 2019 Dec 4;223(6):337-349. Epub 2019 Dec 4.

Institut für Rettungs-und Notfallmedizin, Universitätsklinikum Schleswig-Holstein.

As far as prehospital but in part also clinical obstetrics is concerned, the acute nature of perinatal emergencies is overshadowed by limited diagnostic and therapeutic options. The need for acute and targeted intervention may result from both maternal and fetal indications. As common in emergency services for pregnant women, prehospital primary assessment and logistics management (e. Read More

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http://dx.doi.org/10.1055/a-1021-1873DOI Listing
December 2019

Airborne pollution and pregnancy.

Authors:
E Jauniaux J Grigg

BJOG 2020 02 14;127(3):343-344. Epub 2019 Dec 14.

Centre for Genomics and Child Health, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/1471-0528.16016DOI Listing
February 2020

Association of late second trimester miscarriages with placental histology and autopsy findings.

Eur J Obstet Gynecol Reprod Biol 2019 Dec 22;243:32-35. Epub 2019 Oct 22.

Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.

Objectives: To describe the placental histology and autopsy findings in pregnancies where fetal demise occurred before a gestational age of 22 weeks.

Study Design: This study was a subset of a larger study where the effect of alcohol exposure during pregnancy on stillbirths was studied. In a prospective cohort, 7,010 singleton pregnancies were followed from the first antenatal visit until infant one year of age visit. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876705PMC
December 2019

Exposure to Asian dust within a few days of delivery is associated with placental abruption in Japan: a case-crossover study.

BJOG 2020 02 13;127(3):335-342. Epub 2019 Nov 13.

Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Objective: Asian dust is a natural phenomenon in which dust particles are transported from desert areas in China and Mongolia to East Asia. Short-term exposure to Asian dust has been associated with cardiovascular disease through mechanisms such as systemic inflammation. Because inflammation is a potential trigger of placental abruption, exposure may also lead to abruption. Read More

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http://dx.doi.org/10.1111/1471-0528.15999DOI Listing
February 2020

Traumatic injury in female Drosophila melanogaster affects the development and induces behavioral abnormalities in the offspring.

Behav Brain Funct 2019 Oct 25;15(1):11. Epub 2019 Oct 25.

Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY, 10314, USA.

Traumatic injury (TI) during pregnancy increases the risk for developing neurological disorders in the infants. These disorders are a major concern for the well-being of children born after TI during pregnancy. TI during pregnancy may result in preterm labor and delivery, abruptio placentae, and/or fetomaternal hemorrhage. Read More

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http://dx.doi.org/10.1186/s12993-019-0163-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815055PMC
October 2019
1 Read

Perinatal complications and live-birth outcomes following assisted reproductive technology: a retrospective cohort study.

Chin Med J (Engl) 2019 Oct;132(20):2408-2416

Beijing Jia En De Yun Hospital, Beijing 100191, China.

Background: With the development of assisted reproductive technology (ART) and its increasing success rate in the mainland of China, more attention has been paid to the safety of ART. In this study, we explored the associations between conception by ART and pregnancy/perinatal complications, and neonatal outcomes compared with similar outcomes following spontaneous conception.

Methods: This retrospective cohort study of pregnancies over a 3-year period (2013-2015) was performed at Beijing Obstetrics and Gynecology Hospital, Beijing, China. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831076PMC
October 2019
1 Read

Acute promyelocytic leukemia during pregnancy: A case report and 10-year institutional review of hematologic malignancies during pregnancy.

Pathol Res Pract 2019 Dec 28;215(12):152672. Epub 2019 Sep 28.

Department of Pathology, Divisions of Anatomic and Clinical Pathology, The University of Alabama at Birmingham, Birmingham, AL 35249, USA. Electronic address:

Acute promyelocytic leukemia (APL) manifesting during pregnancy is a very rare but highly challenging gestational complication in part due to its associated profound coagulopathy. We present the case of a 23-year-old Gravida 3 Para 2002 woman admitted to our hospital at 26 weeks of gestation for severe pre-eclampsia with documentation of intrauterine fetal demise (IUFD), thrombocytopenia, and placental abruption. A peripheral blood smear revealed promyelocytes with azure granules, highly concerning for APL. Read More

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http://dx.doi.org/10.1016/j.prp.2019.152672DOI Listing
December 2019
1 Read
1.562 Impact Factor

The impact of pre-pregnancy body mass index and gestational weight gain on placental abruption risk: a systematic review and meta-analysis.

Arch Gynecol Obstet 2019 11 1;300(5):1201-1210. Epub 2019 Oct 1.

Telethon Kids Institute, The University of Western Australia, P.O. Box 855, West Perth, WA, 6872, Australia.

Purpose: The aim of this systematic review was to evaluate the associations between pre-pregnancy body mass index and gestational weight gain and placental abruption.

Methods: Relevant studies were identified from PubMed, EMBASE, Scopus and CINAHL. Unpublished findings from analyses of linked population-based data sets from Western Australia (2012-2015, n = 114,792) were also included. Read More

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http://dx.doi.org/10.1007/s00404-019-05320-8DOI Listing
November 2019

Massive blood transfusion in relation to delivery: incidence, trends and risk factors: a population-based cohort study.

BJOG 2019 12 23;126(13):1577-1586. Epub 2019 Sep 23.

Department of Clinical Sciences and Education, Karolinska Institutet, Stockholm, Sweden.

Objective: To estimate incidence, trends over time, and risk factors for massive blood transfusions in obstetric patients. A secondary aim was to evaluate transfusion ratios in relation to massive transfusion.

Design: Population-based cohort. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1471-0528.15
Publisher Site
http://dx.doi.org/10.1111/1471-0528.15927DOI Listing
December 2019
2 Reads

Cerebrovascular disease after placental abruption: A population-based prospective cohort study.

Neurology 2019 09 16;93(12):e1148-e1158. Epub 2019 Aug 16.

From the Department of Obstetrics, Gynecology, and Reproductive Sciences (C.V.A.), Division of Epidemiology and Biostatistics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ; Department of Health Policy and Administration, Joseph L. Mailman School of Public Health (C.V.A.), Department of Neurology (M.S.V.E.), Division of Neurology Clinical Outcomes Research and Population Sciences (NeuroCORPS), and Department of Epidemiology (M.S.V.E.), Joseph L. Mailman School of Public Health, Columbia University, New York, NY; Department of Public Health (A.V.H., A.-M.N.A.), University of Copenhagen, Denmark; Department of Epidemiology (M.A.W., J.W.R.-E.), Harvard TH Chan School of Public Health; and Department of Medicine (J.W.R.-E.), Division of Women's Health, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

Objective: To test whether abruption during pregnancy is associated with long-term cerebrovascular disease by assessing the incidence and mortality from stroke among women with abruption.

Methods: We designed a population-based prospective cohort study of women who delivered in Denmark from 1978 to 2010. We used data from the National Patient Registry, Causes of Death Registry, and Danish Birth Registry to identify women with abruption, cerebrovascular events, and deaths. Read More

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http://dx.doi.org/10.1212/WNL.0000000000008122DOI Listing
September 2019
1 Read

Temperature, placental abruption and stillbirth.

Environ Int 2019 10 31;131:105067. Epub 2019 Jul 31.

Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, 1200 Pressler St., Houston, TX 77030, USA; Southwest Center for Occupational and Environmental Health (SWCOEH), UTHealth School of Public Health, 1200 Pressler St., Houston, TX 77030, USA. Electronic address:

Background: Pregnant women may be vulnerable to changes in ambient temperature and warming climates. Recent evidence suggests that temperature increases are associated with placental abruption, a risk factor for stillbirth.

Objectives: We investigated the effect of acute exposures to apparent temperature on stillbirths in Harris County, Texas, 2008-2013. Read More

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http://dx.doi.org/10.1016/j.envint.2019.105067DOI Listing
October 2019
5.559 Impact Factor

Effects of maternal smoking on human placental vascularization: A systematic review.

Taiwan J Obstet Gynecol 2019 Jul;58(4):454-459

Emergency Hospital of Cluj-Napoca - Dominic Stanca Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania.

The abnormal development of placental vascularization leads to placental insufficiency, which further reduces the nutrient and trace exchange between maternal circulation and fetal circulation. These changes cause maternal and fetal complications. The objective of our systematic review was to explore the effects of maternal smoking on placental vascularization. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.05.004DOI Listing

Anticonvulsant Mood Stabilizer and Lithium Use and Risk of Adverse Pregnancy Outcomes.

J Clin Psychiatry 2019 06 18;80(4). Epub 2019 Jun 18.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Objective: To determine the comparative safety of mood stabilizers with respect to risk of preeclampsia, placental abruption, growth restriction, and preterm birth.

Methods: A cohort study was carried out using Medicaid Analytic eXtract data for pregnant women linked to live born infants enrolled from 2000 to 2010. Exposure to lamotrigine, valproate, topiramate, carbamazepine, oxcarbazepine, and lithium during the first 20 weeks of pregnancy was assessed. Read More

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http://dx.doi.org/10.4088/JCP.18m12572DOI Listing
June 2019
2 Reads

Hypertensive disorders in pregnancy and maternal and neonatal outcomes in Haiti: the importance of surveillance and data collection.

BMC Pregnancy Childbirth 2019 Jun 20;19(1):208. Epub 2019 Jun 20.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Background: This study aims to determine reported prevalence of hypertensive disorders in pregnancy (HDP) and maternal and neonatal outcomes associated with these disorders among women delivering at selected hospitals across Haiti.

Methods: A retrospective review of 8822 singleton deliveries between January 2012 and December 2014 was conducted at four hospitals in separate Departments across Haiti. Researchers examined the proportion of women with reported HDP (hypertension, preeclampsia, eclampsia) and the association between women with HDP and three neonatal outcomes: low birth weight, preterm birth, and stillbirths; and two maternal outcomes: placental abruption and maternal death in Hôpital Albert Schweitzer (HAS). Read More

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https://bmcpregnancychildbirth.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12884-019-2361-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585002PMC
June 2019
24 Reads

Placental bed research: I. The placental bed: from spiral arteries remodeling to the great obstetrical syndromes.

Am J Obstet Gynecol 2019 11 1;221(5):437-456. Epub 2019 Jun 1.

Department of Gynecology, Obstetrics, and Urology, Sapienza, University of Rome, Rome, Italy.

The term placental bed was coined to describe the maternal-fetal interface (ie, the area in which the placenta attaches itself to the uterus). Appropriate vascularization of this area is of vital importance for the development of the fetus; this is why systematic investigations of this area have now been carried out. Initially, the challenge was the identification and classification of the various successive branching of uterine arteries in this area. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.05.044DOI Listing
November 2019
24 Reads

Placental abruption and long-term neurological hospitalisations in the offspring.

Paediatr Perinat Epidemiol 2019 05;33(3):215-222

Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Background: Placental abruption is a major determinant of maternal and perinatal morbidity and mortality, often related to asphyxia and preterm birth. However, the impact of abruption on the long-term morbidity of the offspring is less investigated.

Methods: We designed a hospital-based cohort study, in which the incidence of long-term neurology-related hospitalisations of offspring to women with and without placental abruption was assessed. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ppe.12553
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http://dx.doi.org/10.1111/ppe.12553DOI Listing
May 2019
18 Reads
2.811 Impact Factor

Placental abruption and neurological disorders in children: Are the associations robust?

Paediatr Perinat Epidemiol 2019 05 14;33(3):223-225. Epub 2019 May 14.

Department of Neurology, Division of Neurology Clinical Outcomes Research and Population Sciences (NeuroCORPS), Columbia University, New York, New York.

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http://dx.doi.org/10.1111/ppe.12558DOI Listing
May 2019
4 Reads

The obstetric complications in women with hereditary thrombophilia.

Med Pharm Rep 2019 Apr 25;92(2):106-110. Epub 2019 Apr 25.

Department of Obstetrics and Gynecology No. 1, Nicolae Testemitanu State University of Medicine and Pharmacy, Kishinev, Republic of Moldova.

All congenital thrombophilias are associated with an increased risk of venous thromboembolism (VTE) during pregnancy. Several studies have confirmed the increased risk of obstetric complications in women with congenital thrombophilias. Case-control, cohort and transversal studies have shown that hereditary thrombophilia is more prevalent in the cohorts of women with pregnancy losses, early onset preeclampsia, abruptio placentae and IUGR. Read More

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http://dx.doi.org/10.15386/cjmed-1097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510366PMC
April 2019
7 Reads

Re-evaluation of abruptio placentae and other maternal complications during expectant management of early onset pre-eclampsia.

Pregnancy Hypertens 2019 Apr 27;16:38-41. Epub 2019 Feb 27.

Department of Obstetrics & Gynaecology, Stellenbosch University and Tygerberg Hospital, Francie Van Zijl Drive, Tygerberg, 7505, South Africa. Electronic address:

Objective: Expectant management of appropriately selected cases of early pre-eclampsia in a dedicated, tertiary in-patient setting with frequent non-invasive maternal and fetal surveillance, prolongs pregnancy, improves perinatal outcome and mitigates the impact of maternal complications. As the rate of abruptio placentae in a large descriptive study performed nearly 20 years ago was 20%, a study to re-evaluate the rate of abruptio placentae and other maternal complications was performed.

Study Design: A retrospective study that included all women admitted for expectant management with stable early pre-eclampsia (≥24 and <34 weeks' gestation) was performed at Tygerberg Hospital, a secondary and tertiary referral centre in South Africa over a period of 12 months. Read More

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http://dx.doi.org/10.1016/j.preghy.2019.02.008DOI Listing
April 2019
10 Reads

Electronic fetal monitoring characteristics of a patient with sudden onset of placental abruption and intrauterine fetal demise: A case report.

Medicine (Baltimore) 2019 May;98(18):e15472

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Introduction: Placental abruption (PA) is a serious complication of pregnancy, associated with significant perinatal complications, including intrauterine fetal demise (IUFD). Continuous electronic fetal monitoring (EFM) has been widely applied in China in recent decades. Exploration of potentially PA-specific patterns of EFM contributes to early detection of PA occurrence. Read More

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http://dx.doi.org/10.1097/MD.0000000000015472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504280PMC
May 2019
8 Reads

Hepatic rupture from haematomas in patients with pre-eclampsia/eclampsia: a case series.

Pan Afr Med J 2018 4;31:86. Epub 2018 Oct 4.

Department of Obstetrics and Gynaecology, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe.

Hepatic rupture from haematomas is a rare complication of severe preeclampsia/eclampsia especially when complicated with the haemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome. It is associated with poor maternal and foetal outcomes as demonstrated by three cases we describe. The first case had eclampsia at 31 weeks gestation with features of abruptio placentae and at caesarean section we found haemoperitoneum of 1. Read More

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http://www.panafrican-med-journal.com/content/article/31/86/
Publisher Site
http://dx.doi.org/10.11604/pamj.2018.31.86.15975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462150PMC
April 2019
22 Reads

Analysis of 62 placental abruption cases: Risk factors and clinical outcomes.

Taiwan J Obstet Gynecol 2019 Mar;58(2):223-226

Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun 130041, China. Electronic address:

Objective: This study aimed to explore the clinical characteristics and outcomes of placental abruption.

Materials And Methods: A total of 62 placental abruption cases were collected from the Second Hospital of Jilin University between January 2007 and December 2012. A retrospective study was conducted to explore the risk factors for placental abruption, clinical characteristics, and maternal and fetal outcomes. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.01.010DOI Listing
March 2019
9 Reads
1.261 Impact Factor

Maternal outcomes following massive obstetric haemorrhage in an inner-city maternity unit.

J Obstet Gynaecol 2019 Jul 1;39(5):601-605. Epub 2019 Mar 1.

a Department of Obstetrics and Gynaecology , North Middlesex University Hospital , London , UK.

This retrospective study evaluates the effects of a massive postpartum haemorrhage (PPH) on maternal outcomes in an inner-city London hospital. One hundred and eighty-four cases of a massive primary PPH (>2000 mL) were identified over a seven-year period. A sub-group analysis was performed to assess whether 2000-3000 mL blood loss (134 cases) was associated with specific maternal characteristics or reduced adverse outcomes compared with >3000 mL blood loss (50 cases). Read More

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http://dx.doi.org/10.1080/01443615.2018.1534814DOI Listing
July 2019
38 Reads

Genetic risk assessment of thrombophilia in patients with adverse obstetric outcomes.

PLoS One 2019 27;14(2):e0211114. Epub 2019 Feb 27.

BCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), Barcelona, Spain.

Objectives: To investigate the incidence of inherited thrombophilias in patients with adverse obstetric outcomes and to compare detection rates of thrombophilias between standard blood tests and a novel genetic test.

Methods: This is a case-control prospective study performed in Hospital Sant Joan de Déu in Barcelona, Spain. Cases had a history of intrauterine growth restriction requiring delivery before 34 weeks gestation, placental abruption before 34 weeks gestation, or severe preeclampsia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392221PMC
November 2019
9 Reads

Unexpected term NICU admissions: a marker of obstetrical care quality?

Am J Obstet Gynecol 2019 04 17;220(4):395.e1-395.e12. Epub 2019 Feb 17.

Departments of Obstetrics and Gynecology and Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Harvard University, Boston, MA.

Background: Unexpected admissions of term neonates to the neonatal intensive care unit and unexpected postnatal complications have been proposed as neonatal-focused quality metrics for intrapartum care. Previous studies have noted significant variation in overall hospital neonatal intensive care unit admission rates; however, little is known about the influence of obstetric practices on these rates or whether variation among unanticipated admissions in low-risk, term neonates can be attributed to systemic hospital practices.

Objective: The objective of the study was to examine the relative effects of patient characteristics and intrapartum events on unexpected neonatal intensive care unit admissions and to quantify the between-hospital variation in neonatal intensive care unit admission rates among this group of neonates. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193032
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http://dx.doi.org/10.1016/j.ajog.2019.02.001DOI Listing
April 2019
4 Reads

The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort.

BMC Pregnancy Childbirth 2019 Feb 19;19(1):75. Epub 2019 Feb 19.

The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Background: Homocysteine is an intermediate metabolite implicated in the risk of placenta-mediated complications, including preeclampsia, placental abruption, fetal growth restriction, and pregnancy loss. Large cohort and case-control studies have reported inconsistent associations between homocysteine and these complications. The purpose of this study was to investigate whether elevated maternal plasma homocysteine concentration in the early to mid-second trimester is associated with an increased risk of placenta-mediated complications. Read More

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http://dx.doi.org/10.1186/s12884-019-2219-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381683PMC
February 2019
27 Reads

Placental findings among newborns with hypoxic ischemic encephalopathy.

J Perinatol 2019 04 15;39(4):563-570. Epub 2019 Feb 15.

Department of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, RI, USA.

Objective: To determine if pre-specified placental abnormalities among newborns with hypoxic-ischemic encephalopathy (HIE) differ compared to newborns admitted to a NICU without encephalopathy.

Study Design: Retrospective case-control study of newborns with HIE (2006-2014) and controls matched for birth year, gestational age, weight, and gender. One pathologist reviewed archived placental sections using pre-specified criteria. Read More

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http://dx.doi.org/10.1038/s41372-019-0334-9DOI Listing
April 2019
2 Reads

Bloody amniotic fluid during labor - Prevalence, and association with placental abruption, neonatal morbidity, and adverse pregnancy outcomes.

Eur J Obstet Gynecol Reprod Biol 2019 Mar 17;234:103-107. Epub 2019 Jan 17.

Department of Obstetrics & Gynecology, The Edith Wolfson Medical Center, Holon, Israel Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Objective: To study the association between bloody amniotic fluid (BAF) during labor and adverse pregnancy outcomes.

Study Design: In the last 10 years we have implemented an institutional protocol that mandates obstetricians/midwives to report their subjective impression of the color of amniotic fluid (clear, meconium stained, bloody) during labor. The medical records, and neonatal charts of all singleton deliveries ≥ 37 weeks between 2008-2018 were reviewed. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.01.011DOI Listing
March 2019
10 Reads

A "miracle" pregnancy outcome of severe placental abruption.

Horm Mol Biol Clin Investig 2019 Jan 17;38(3). Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Sibu Hospital, Ministry of Health Malaysia, 96000 Sibu, Sarawak, Malaysia.

Severe placental abruption is associated with high maternal and perinatal morbidity and mortality. Prompt delivery is usually mandatory in this situation. We report a case of a 33-year-old woman, gravida 5, para 3 + 1, at 26 weeks + 3 days' gestation who had severe placental abruption involving 40% of the placental surface complicated with maternal moderate anaemia and thrombocytopenia. Read More

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http://www.degruyter.com/view/j/hmbci.ahead-of-print/hmbci-2
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http://dx.doi.org/10.1515/hmbci-2018-0059DOI Listing
January 2019
34 Reads

Avoiding paternalism but not moral perplexity.

Authors:
D R Hall

S Afr Med J 2018 Oct 26;108(11):915-916. Epub 2018 Oct 26.

Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

Maternal autonomy has replaced medical paternalism, but conflicts between beneficence and autonomy persist. Read More

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http://dx.doi.org/10.7196/SAMJ.2018.v108i11.13328DOI Listing
October 2018
7 Reads

Childhood abuse, intimate partner violence, and placental abruption among Peruvian women.

Ann Epidemiol 2019 03 21;31:26-31. Epub 2018 Dec 21.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

Purpose: Experiencing childhood abuse (CA) or intimate partner violence (IPV) has been linked to adverse pregnancy outcomes. We examined whether CA history and current IPV are independently and jointly associated with placental abruption (PA).

Methods: We recruited 662 PA cases and 665 controls in Lima, Peru. Read More

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http://dx.doi.org/10.1016/j.annepidem.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420388PMC
March 2019
7 Reads

Multifocal Rounded Intraplacental Hematomas, Placental Abruption and Intrauterine Fetal Demise.

Fetal Pediatr Pathol 2018 Dec 28;37(6):465-469. Epub 2018 Dec 28.

b Laboratory , Children's Hospital of New Orleans , New Orleans , Louisiana , USA.

Background: Rounded intraplacental hematomas (RIH) have a distinct rounded hemorrhagic appearance located within the placental parenchyma. Hemorrhagic villous infarctions (infarcts that when sectioned have hemorrhagic centers) are probably older RIH. RIH have been associated with acute abruptions. Read More

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http://dx.doi.org/10.1080/15513815.2018.1520373DOI Listing
December 2018
3 Reads

[INTERVENTIONS FOR SUPPORTING WOMEN TO STOP SMOKING IN PREGNANCY].

Harefuah 2018 Dec;157(12):783-786

Department of Gynecology and Obstetrics, Rambam Health Care Campus, affiliated with Technion-Israel Institute of Technology, Haifa, Israel.

Introduction: Smoking during pregnancy is a public health problem because of the many adverse effects associated with it. These include intrauterine growth restriction, placenta previa, abruptio placentae, decreased maternal thyroid function, preterm premature rupture of membranes, low birth weight, perinatal mortality, and ectopic pregnancy. An estimated 5-8% of pre-term deliveries, 13-19% of term deliveries of infants with low birth weight, 23-34% cases of sudden infant death syndrome (SIDS), and 5-7% of preterm-related infant deaths can be attributed to prenatal maternal smoking. Read More

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December 2018
41 Reads

[Epidemiological characteristics and related risk factors on placental abruption in Hebei province].

Zhonghua Liu Xing Bing Xue Za Zhi 2018 Dec;39(12):1621-1625

Department of Obstetrics and Gynecology, Hebei General Hospital, Shijiazhuang 050000, China.

The aim of this study was to assess the risk factors and epidemiological characteristics of placental abruption (PA) in Hebei province. A cross-sectional survey was conducted to collect data on 218 880 pregnant women who were hospitalized in 22 hospitals which were under a monitoring program, in Hebei province, from January 1, 2013 to December 31, 2016. Data regarding epidemiological characteristics as time distribution, population distribution and related risk factors of placental abruption were gathered and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2018.12.016DOI Listing
December 2018
8 Reads