2,970 results match your criteria Abruptio Placentae

Impact of endocrine disorders on stillbirth: a prospective cohort study.

Gynecol Endocrinol 2022 May 4:1-5. Epub 2022 May 4.

International Doctorate School in Clinical and Experimental Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.

Objective: Among risk factors for SB, maternal endocrine diseases (ED), such as thyroids dysfunction and gestational diabetes mellitus (GDM), are the most frequent. This study aimed to investigate the rate of ED in a population of SB cases collected prospectively, and the relationship between these and causes of death.

Methods: This is an area-based, prospective cohort study conducted in Emilia-Romagna, Italy between January 2014 and December 2020. Read More

View Article and Full-Text PDF

Roberts syndrome with tetraphocomelia: A case report and literature review.

SAGE Open Med Case Rep 2022 21;10:2050313X221094077. Epub 2022 Apr 21.

Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.

Roberts syndrome is a rare genetic disorder characterized by symmetrical reductive limb malformation and craniofacial abnormalities. It is caused by mutation in the "Establishment of cohesion 1 homolog 2" genes, resulting in the loss of acetyltransferase activities and manifesting as premature centromere separation in metaphase chromosomes. The affected individual grows slowly during pregnancy and after birth with associated mild to severe intellectual impairment. Read More

View Article and Full-Text PDF

A praeeclampsia két arca.

Orv Hetil 2022 Apr 24;163(17):663-669. Epub 2022 Apr 24.

1 Pécsi Tudományegyetem, Egészségtudományi Kar, Doktori Iskola Pécs Magyarország.

Összefoglaló. Egészséges terhességben mintegy két literrel nő a vér mennyisége. A vérvolumen növekedésének elmaradása, de extrém mértékű növekedése is súlyos következményekkel szövődhet. Read More

View Article and Full-Text PDF

Perinatal outcomes of women with Müllerian anomalies.

Arch Gynecol Obstet 2022 Apr 15. Epub 2022 Apr 15.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, No. 20, 3rd section, South Renmin Road, Chengdu, 610041, Sichuan, China.

Purpose: To investigate the perinatal outcomes of singleton pregnant women with Müllerian anomalies (MuAs).

Methods: A retrospective cohort study was conducted on singleton pregnant women with MuAs who delivered at the West China Second University Hospital between January 1, 2009 and December 31, 2020.

Results: Four hundred fifty-seven cases of MuAs were identified, with an incidence of 0. Read More

View Article and Full-Text PDF

Longitudinal changes in angiogenesis biomarkers within 72 h of diagnosis and time-to-delivery in early-onset preeclampsia.

Pregnancy Hypertens 2022 Mar 30;28:139-145. Epub 2022 Mar 30.

Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (imas12), Universidad Complutense de Madrid, Madrid, Spain. Electronic address:

Objectives: To evaluate the association between the increment of the sFlt-1/PlGF ratio within the first 72 h after the diagnosis of early-onset preeclampsia (PE) and the time-to-delivery. Secondarily we aimed to test its predictive value for maternal adverse outcomes.

Study Design: Retrospective cohort study of 155 women with early-onset PE and measurement of sFlt-1/PlGF at diagnosis and delivery from which the expected distributions of the daily increment (Δ) of sFlt-1/PlGF ratio, sFlt-1 and PlGF were obtained. Read More

View Article and Full-Text PDF

The environmental risk factors prior to conception associated with placental abruption: an umbrella review.

Syst Rev 2022 Apr 1;11(1):55. Epub 2022 Apr 1.

School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: The present umbrella review evaluated risk factors prior to conception associated with placental abruption based on meta-analyses and systematic reviews.

Methods: We searched PubMed, Scopus, and Web of Science until June 25, 2021. All meta-analyses that had focused on assessing the risk factors associated with placental abruption were included. Read More

View Article and Full-Text PDF

Levothyroxine Supplementation in Euthyroid Pregnant Women With Positive Autoantibodies: A Systematic Review and Meta-Analysis.

Front Endocrinol (Lausanne) 2022 17;13:759064. Epub 2022 Feb 17.

Center for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy.

Objectives: To explore the role of levothyroxine (LT4) supplementation in affecting the outcome of pregnant euthyroid women with thyroperoxidase (TPO) antibodies.

Methods: MEDLINE, EMBASE, Google Scholar, and the Web of Science databases were searched. The primary outcome was pre-term birth (PTB), defined as live birth before 37 weeks of gestation; secondary outcomes were gestational hypertension, pre-eclampsia (PE), placental abruption, miscarriage, intra-uterine death (IUD), and admission to neonatal intensive care unit (NICU). Read More

View Article and Full-Text PDF

Assessment of placental abruption with diffusion-weighted imaging.

J Obstet Gynaecol Res 2022 Apr 22;48(4):930-937. Epub 2022 Feb 22.

Department of Obstetrics and Gynaecology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Aim: To investigate whether placental abruption without fetal distress could be assessed by apparent diffusion coefficient (ADC) values in magnetic resonance imaging (MRI).

Methods: We conducted a retrospective case-control study at a single center. ADC values at the lesions of placental abruption in the abruption group (n = 8) were compared to those in the control group (n = 32). Read More

View Article and Full-Text PDF

Pregnancy complications and risk of uterine rupture among women with singleton pregnancies in China.

BMC Pregnancy Childbirth 2022 Feb 16;22(1):131. Epub 2022 Feb 16.

National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Background: The goal of this study was to investigate whether pregnancy complications are associated with an increased risk of uterine rupture (UR) and how that risk changes with gestational age.

Methods: We obtained all data from China's National Maternal Near Miss Surveillance System (NMNMSS) between 2012 and 2018. Poisson regression analysis was used to assess the risk of UR with pregnancy complications (preeclampsia, gestational diabetes mellitus, placental abruption, placenta previa and placenta percreta) among 9,454,239 pregnant women. Read More

View Article and Full-Text PDF
February 2022

Maternal Outcomes of Eclampsia at the Lagos University Teaching Hospital: A Six-Year Retrospective Review.

West Afr J Med 2022 Jan;39(1):20-23

Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos/Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria.

Background: Eclampsia is one of the leading causes of maternal morbidity and mortality.

Objectives: To determine the incidence as well as the maternal outcomes of eclampsia at the Lagos University Teaching Hospital (LUTH).

Methods: This was a retrospective review. Read More

View Article and Full-Text PDF
January 2022

Optimal blood pressure target to prevent severe hypertension in pregnancy: A systematic review and meta-analysis.

Hypertens Res 2022 May 8;45(5):887-899. Epub 2022 Feb 8.

Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan.

Severe hypertension in pregnancy is a hypertensive crisis that requires urgent and intensive care due to its high maternal and fetal mortality. However, there is still a conflict of opinion on the recommendations of antihypertensive therapy. This study aimed to identify the optimal blood pressure (BP) levels to prevent severe hypertension in pregnant women with nonsevere hypertension. Read More

View Article and Full-Text PDF

Adverse perinatal outcomes in a large United States birth cohort during the COVID-19 pandemic.

Am J Obstet Gynecol MFM 2022 May 1;4(3):100577. Epub 2022 Feb 1.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, George Washington University, Washington, DC (Dr Ahmadzia).

Background: The impact of coronavirus disease 2019 (COVID-19) on adverse perinatal outcomes remains unclear.

Objective: This study aimed to investigate whether COVID-19 is associated with adverse perinatal outcomes in a large national dataset and to examine the rates of adverse outcomes during the pandemic compared with the rates of adverse outcomes during the prepandemic period.

Study Design: This observational cohort study included 683,905 patients, between the ages of 12 and 50, hospitalized for childbirth and abortion between January 1, 2019, and May 31, 2021. Read More

View Article and Full-Text PDF

Maternal and neonatal complications in women with medical comorbidities and preeclampsia.

Pregnancy Hypertens 2022 Mar 16;27:62-68. Epub 2021 Dec 16.

Department of Obstetrics and Gynaecology, Monash University, Level 5, Monash Medical Centre, 246 Clayton Road, Clayton 3168, Victoria, Australia; Monash Womens' and Newborn, Monash Health, 246 Clayton Road, Clayton 3168, Victoria, Australia.

Objectives: To evaluate how medical comorbidities - chronic hypertension, pre-gestational or gestational diabetes and obesity - influence maternal and neonatal complications from preeclampsia.

Study Design: We undertook a retrospective cohort study of women delivering in Victoria, Australia, between 2009 and 2017. We compared the likelihood of having a maternal complication before delivery or neonatal complication after birth between women with and without comorbidities. Read More

View Article and Full-Text PDF

Correlation of platelet parameters with adverse maternal and neonatal outcomes in severe preeclampsia: A case-control study.

Heliyon 2021 Dec 26;7(12):e08484. Epub 2021 Nov 26.

Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, P.M.B 102 Abakaliki, Ebonyi state, Nigeria.

Background: Pre-eclampsia (PET) is a potentially devastating multi-systemic disorder resulting in the generation of oxidative stress. Platelet activation causes vasoconstriction and release of inflammatory cytokines, resulting in an intensified inflammatory response, endothelial damage, and coagulopathy which culminate in adverse pregnancy outcomes.

Aim: To compare the platelet parameters between preeclamptic and normotensive pregnant women and their relationship to adverse outcomes in women with pre-eclampsia. Read More

View Article and Full-Text PDF
December 2021

Impact of Co-Existing Placental Pathologies in Pregnancies Complicated by Placental Abruption and Acute Neonatal Outcomes.

J Clin Med 2021 Dec 3;10(23). Epub 2021 Dec 3.

Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Placental abruption (PA) is a concern for maternal and neonatal morbidity. Adverse neonatal outcomes in the setting of PA include higher risk of prematurity. Placental pathologies include maternal vascular malperfusion (MVM), fetal vascular malperfusion (FVM), acute chorioamnionitis, and villitis of unknown etiology (VUE). Read More

View Article and Full-Text PDF
December 2021

Maternal-Fetal Outcomes in Women with Endometriosis and Shared Pathogenic Mechanisms.

Medicina (Kaunas) 2021 Nov 17;57(11). Epub 2021 Nov 17.

Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

The connection between endometriosis and pregnancy outcomes is trending among the research topics. Until recently, endometriosis and its painful symptomatology were considered to be alleviated by pregnancy. However, these beliefs have shifted, as emerging literature has demonstrated the role of this condition in affecting pregnancy evolution. Read More

View Article and Full-Text PDF
November 2021

Analysis of Selected Risk Factors Depending on the Type of Cerebral Palsy.

Brain Sci 2021 Oct 30;11(11). Epub 2021 Oct 30.

Department of Pediatric Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.

Cerebral palsy (CP) is not a defined, separate disease classification, but a set of etiologically diverse symptoms that change with the child's age. According to the up-to-date definition, CP is a group of permanent but not unchanging disorders of movement and/or posture and motor function, which are due to a nonprogressive interference, lesion, or abnormality of the developing/immature brain. CP is one of the most frequent causes of motor disability in children. Read More

View Article and Full-Text PDF
October 2021

The role of confounding in the association between pregnancy complications and subsequent preterm birth: a cohort study.

BJOG 2022 May 30;129(6):890-899. Epub 2021 Nov 30.

Curtin School of Population Health, Curtin University, Bentley, Western Australlia, Australia.

Objective: To estimate the degree of confounding necessary to explain the associations between complications in a first pregnancy and the subsequent risk of preterm birth.

Design: Population-based cohort study.

Setting: Western Australia. Read More

View Article and Full-Text PDF

Maternal and neonatal outcomes in pregnancies complicated by eclampsia - analysis of cases from 2008-2018.

Ceska Gynekol 2021 ;86(5):297-303

Objective: Evaluation of perinatal results in a set of pregnancies complicated by eclampsia.

Methods: Analysis of 67,304 births performed at the Department of Gynecology and Obstetrics, Masaryk University, Faculty of Medicine and University Hospital, Brno from 2008-2018. During the given period, eclampsia was dia-gnosed in 16 mothers (0. Read More

View Article and Full-Text PDF
November 2021

Pregnancy and Birth Outcomes during the Early Months of the COVID-19 Pandemic: The MOACC-19 Cohort.

Int J Environ Res Public Health 2021 10 18;18(20). Epub 2021 Oct 18.

Faculty of Medicine, Universidad de Cantabria, 39011 Santander, Spain.

The new coronavirus, SARS-CoV-2, is devastating for specific groups of patients, but currently there is not enough information concerning its effects on pregnant women. The purpose of this study is to identify the impact of SARS-CoV-2 infection on pregnancy and the consequences that it could cause. We studied a cohort of pregnant ladies who were tested for SARS-CoV-2 infection by RT-PCR and classified as infected or not infected. Read More

View Article and Full-Text PDF
October 2021

Trauma and pregnancy: Is flow cytometry detection and quantification of fetal red blood cells useful?

Eur J Obstet Gynecol Reprod Biol 2021 11 17;266:48-54. Epub 2021 Sep 17.

Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, The Hebrew University School of Medicine, Jerusalem, Israel. Electronic address:

Objective: To assess whether positive flow cytometry quantification of fetal red blood cells is associated with adverse maternal and neonatal outcomes in cases of mild trauma during pregnancy.

Study Design: A retrospective database study was conducted at a single tertiary center between 2013 and 2019. All pregnant women with viable gestation involved in trauma who underwent flow cytometry quantification of fetal red blood cells were included in the study. Read More

View Article and Full-Text PDF
November 2021

Placental Abruption after Fetoscopic Laser Surgery in Twin-Twin Transfusion Syndrome: The Role of the Solomon Technique.

Fetal Diagn Ther 2021 23;48(9):660-666. Epub 2021 Sep 23.

Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.

Introduction: Twin-twin transfusion syndrome (TTTS) is a complication in monochorionic twin pregnancies which is preferably treated with fetoscopic laser surgery. A few small studies suggested a possible association between the Solomon laser technique and placental abruption.

Methods: The objective of this study is to compare the rate of and to explore potential risk factors for placental abruption in TTTS treated with fetoscopic laser surgery according to the Selective and Solomon laser technique. Read More

View Article and Full-Text PDF
November 2021

Factor V Leiden G1691A and Prothrombin Gene G20210A Mutations on Pregnancy Outcome.

Cureus 2021 Aug 15;13(8):e17185. Epub 2021 Aug 15.

Internal Medicine, JC Medical Center, Orlando, USA.

Factor V Leiden (FVL) G1619A mutation and prothrombin gene (PTG) G20210A are the most common inherited thrombophilias. They have been associated with various obstetric complications such as venous thromboembolism, recurrent pregnancy loss, preeclampsia, abruptio placentae, and small for gestational age fetus. The prevalence of these two mutations is 3-15% in Caucasians and is assumed to be far less common in other ethnic populations. Read More

View Article and Full-Text PDF

Determinants of the decision-to-delivery interval and the effect on perinatal outcome after emergency caesarean delivery: a cross-sectional study.

Malawi Med J 2021 03;33(1):28-36

Obstetrics & Gynaecology Department, University of Ilorin/University of Ilorin Teaching Hospital, PMB 1515, Ilorin, Nigeria.

Background: Preventing prolongation of the decision-to-delivery interval (DDI) for emergency caesarean delivery (CD) remains central to improving perinatal health. This study evaluated the effects of the DDI on perinatal outcome following emergency CD.

Methods: A prospective cross-sectional study involving 205 consenting women who had emergency CD at a tertiary hospital in Nigeria was conducted. Read More

View Article and Full-Text PDF

Utero-placental apoplexy during induction of therapeutic abortion in a 18-week pregnancy.

Eur Rev Med Pharmacol Sci 2021 Jul;25(13):4456-4458

Department of Gynecology and Obstetrics - University of L'Aquila (Italy), Medical School, University of L'Aquila, L'Aquila, Italy.

Utero-Placental Apoplexy, or Couvelaire Uterus, is a third-trimester major obstetrical complication, occurring especially during labor. It consists of placental abruption followed by an acute intradecidual hemorrhage produced by the rupture of the uterus-placental spiral arterioles leading to a retroplacental hematoma. This hemorrhage infiltrates the uterine wall up to intra- and retro-peritoneal areas. Read More

View Article and Full-Text PDF

Shock caused by spontaneous rupture uterine vessels during puerperal period: a case report and literature review.

Eur Rev Med Pharmacol Sci 2021 07;25(13):4451-4455

Tianjin Third Central Hospital, Obstetrics & Gynecology Department, Hedong District, China; Technology Research Central of Public Health Ministry, Tianjin, China.

Hemoperitoneum caused by spontaneous rupture of uterine vessels during delivery is relatively rare in obstetric hemorrhage, and even rarer during the puerperal period. It can be life-threatening without timely diagnosis and treatment; therefore, the literature on this topic is very scarce. To explore its etiology and identify its diagnosis and treatment principle, we are reporting a case of shock caused by spontaneous rupture of uterine vessels admitted in our hospital. Read More

View Article and Full-Text PDF

Maternal Cardiovascular and Cerebrovascular Health After Placental Abruption: A Systematic Review and Meta-Analysis (CHAP-SR).

Am J Epidemiol 2021 12;190(12):2718-2729

Placental abruption and cardiovascular disease (CVD) have common etiological underpinnings, and there is accumulating evidence that abruption may be associated with future CVD. We estimated associations between abruption and coronary heart disease (CHD) and stroke. The meta-analysis was based on the random-effects risk ratio (RR) and 95% confidence interval (CI) as the effect measure. Read More

View Article and Full-Text PDF
December 2021

Intrauterine fetoscopic closure of myelomeningocele: Clinical case and literature review.

Taiwan J Obstet Gynecol 2021 Jul;60(4):766-770

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Żwirki I Wigury Str. 61, 02-091, Warsaw, Poland.

Objective: Spina bifida (SB) is a congenital birth defect defined as a failure of the neural tube formation during the embryonic development phase. Fetoscopic repair of SB is a novel treatment technique that allows to close spinal defect early and prevent potential neurological and psychomotor complications.

Case Report: We present a case report of a 32-year-old-multigravida whose fetus was diagnosed with lumbosacral myelomeningocele at 23rd week. Read More

View Article and Full-Text PDF

Molecular Changes on Maternal-Fetal Interface in Placental Abruption-A Systematic Review.

Int J Mol Sci 2021 Jun 21;22(12). Epub 2021 Jun 21.

Center of Postgraduate Medical Education, Second Department of Obstetrics and Gynecology, 01-809 Warsaw, Poland.

Placental abruption is the separation of the placenta from the lining of the uterus before childbirth. It is an infrequent perinatal complication with serious after-effects and a marked risk of maternal and fetal mortality. Despite the fact that numerous placental abruption risk factors are known, the pathophysiology of this issue is multifactorial and not entirely clear. Read More

View Article and Full-Text PDF

Successful outcome of giant chorioangioma.

J Family Med Prim Care 2021 May 31;10(5):2038-2040. Epub 2021 May 31.

Department of Cytopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Chorioangioma is the most common benign non trophoblastic tumor of the placenta. It is a rare presentation with incidence of 0.6-1% of all pregnancies. Read More

View Article and Full-Text PDF