1,804 results match your criteria Abortion Incomplete

Fatal necrotizing fasciitis in illegal abortion and the negligence tort.

Leg Med (Tokyo) 2021 Jun 7;53:101927. Epub 2021 Jun 7.

Department of Forensic Medicine & Toxicology, Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry 605006, India; Department of Forensic Medicine & Toxicology, Jawaharlal Institute of Postgraduate Medical Education & Research, Karaikal, India.

The present paper is a case-based review on rare complications of illegal abortion, i.e., necrotizing fasciitis missed early by the treating gynecologists which landed up into a negligence tort against the physicians. Read More

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Post-abortion care services at Red Sea State - Sudan.

J Family Med Prim Care 2021 Feb 27;10(2):780-782. Epub 2021 Feb 27.

Associate Professor, Kassala University, Sudan.

Background: Although there are safe and effective methods of abortion, unsafe abortions still widely spread, mainly in underdeveloped countries.

Objective: Study of post abortion care services at Red Sea State to address rate and utilization of post-abortion care package.

Methods: This is a descriptive (observational hospital-based study), conducted at Port Sudan Maternity hospital (May 2018-May 2019). Read More

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February 2021

Determination of misoprostol acid in plasma samples by UPLC-MS/MS with application in a maternal-fetal pharmacokinetic study following a low misoprostol dose vaginally to induce labor.

J Pharm Biomed Anal 2021 Aug 11;202:114138. Epub 2021 May 11.

Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address:

Misoprostol is a prostaglandin E1 synthetic analogous used for elective interruptions of early pregnancy, treatment of incomplete abortion, postpartum hemorrhage and induction of full-term labor. Its a lipophilic drug, passing by extensive and rapid pre-systemic metabolism into the active metabolite, misoprostol acid (MA). The objective of this study was to develop and validate a highly sensitive method for MA determination in plasma using UPLC-MSMS, with application in a study of maternal-fetal pharmacokinetics in healthy parturients women (n = 10) after administration of 25 μg misoprostol vaginally. Read More

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The circadian clock ensures successful DNA replication in cyanobacteria.

Proc Natl Acad Sci U S A 2021 May;118(20)

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637;

Disruption of circadian rhythms causes decreased health and fitness, and evidence from multiple organisms links clock disruption to dysregulation of the cell cycle. However, the function of circadian regulation for the essential process of DNA replication remains elusive. Here, we demonstrate that in the cyanobacterium , a model organism with the simplest known circadian oscillator, the clock generates rhythms in DNA replication to minimize the number of open replication forks near dusk that would have to complete after sunset. Read More

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A Stalled Revolution? Misoprostol and the Pharmaceuticalization of Reproductive Health in Francophone Africa.

Siri Suh

Front Sociol 2021 12;6:590556. Epub 2021 Apr 12.

Brandeis University, Waltham, MA, United States.

Misoprostol entered the global market under the name Cytotec in the mid-1980s for the treatment of gastric ulcers. Decades of research have since demonstrated the safety and effectiveness of off-label use of misoprostol as a uterotonic in pregnant women to prevent and treat post-partum hemorrhage, treat incomplete abortion, or terminate first-trimester pregnancy. Global health experts emphasize misoprostol's potential to revolutionize access to reproductive health care in developing countries. Read More

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The Impact of Abortion Underreporting on Pregnancy Data and Related Research.

Matern Child Health J 2021 Apr 30. Epub 2021 Apr 30.

Guttmacher Institute, 125 Maiden Lane, 7th Floor, New York, NY, 10038, USA.

Introduction: The impact on research findings that use pregnancy data from surveys with underreported abortions is not well-established. We estimate the percent of all pregnancies missing from women's self-reported pregnancy histories because of abortion underreporting.

Methods: We obtained abortion and fetal loss data from the 2006-2015 National Survey of Family Growth (NSFG), annual counts of births from US vital statistics, and external abortion counts from the Guttmacher Institute. Read More

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Risk factors associated to neural tube defects among mothers who gave birth in North Shoa Zone Hospitals, Amhara Region, Ethiopia 2020: Case control study.

PLoS One 2021 26;16(4):e0250719. Epub 2021 Apr 26.

Epidemiology Department, Institute of Health Science, Jimma University, Jimma, Ethiopia.

Introduction: Neural tube defects affect the brain and the spinal cord of the developing embryo. The defects occur due to incomplete or failure of closure of the neural tube. The condition eventually causes death and lifelong disability. Read More

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Perspectives on self-managed abortion among providers in hospitals along the Texas-Mexico border.

BMC Womens Health 2021 03 30;21(1):132. Epub 2021 Mar 30.

Advancing New Standards in Reproductive Health (ANSIRH), Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, 1330 Broadway, Suite 1100, Oakland, CA, 94612, USA.

Background: Following self-managed abortion (SMA), or a pregnancy termination attempt outside of the formal health system, some patients may seek care in an emergency department. Information about provider experiences treating these patients in hospital settings on the Texas-Mexico border is lacking.

Methods: The study team conducted semi-structured interviews with physicians, advanced practice clinicians, and nurses who had experience with patients presenting with early pregnancy complications in emergency and/or labor and delivery departments in five hospitals near the Texas-Mexico border. Read More

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Clinical Conundrum: Neisseria meningitidis Septic Abortion.

J Obstet Gynaecol Can 2021 04;43(4):497-499

Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS.

Septic shock after abortion is an important cause of global maternal mortality but is rarely encountered in developed countries. We describe a case of septic abortion with a novel associated pathogen: Neisseria meningitidis. A 30-year-old multiparous woman presented in septic shock after an incomplete spontaneous abortion. Read More

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Women's experiences using drugs to induce abortion acquired in the informal sector in Colombia: qualitative interviews with users in Bogotá and the Coffee Axis.

Sex Reprod Health Matters 2021 Dec;29(1):1890868

Executive Director, Fundación Oriéntame, Bogotá, Colombia.

In 2006, abortion in Colombia was decriminalised under certain circumstances. Yet some women continue to avail themselves of ways to terminate pregnancies outside of the formal health system. In-depth interviews (IDIs) with women who acquired drugs outside of health facilities to terminate their pregnancies (= 47) were conducted in Bogotá and the Coffee Axis in 2018. Read More

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December 2021

Medical management of induced and incomplete first-trimester abortion by non-physicians in low- and middle-income countries: A systematic review and meta-analysis of randomized controlled trials.

Acta Obstet Gynecol Scand 2021 04 18;100(4):718-726. Epub 2021 Mar 18.

Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Introduction: Unsafe abortion is the cause of a substantial number of maternal mortalities and morbidities globally, but specifically in low- and middle-income countries. Medical abortion methods provided by non-physicians may be a way to reduce the burden of unsafe abortions. Currently, only one systematic review comparing non-physicians with physicians for medical abortion exists. Read More

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Perampanel and pregnancy.

Epilepsia 2021 Mar;62(3):698-708

Department of Neuroscience, Central Clinical School, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia.

Objective: The objective was to summarize pregnancy and fetal/postnatal outcomes following maternal perampanel exposure using preclinical and clinical data, and to use physiologically based pharmacokinetic (PBPK) modeling to improve understanding of perampanel pharmacokinetics (PK) during pregnancy.

Methods: Preclinical developmental studies with perampanel were conducted in pregnant rats and rabbits. Clinical data were collated from the Eisai global perampanel safety database, comprising reports of perampanel exposure during pregnancy from routine clinical settings, interventional studies, and non-interventional post-marketing studies, searched for events coded to Medical Dictionary for Regulatory Activities (MedDRA) high-level group terms of Pregnancy, Labor, Delivery, and Postpartum Conditions and/or the Standardized MedDRA Query terms of Congenital, Familiar, and Genetic Disorders. Read More

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Pregnancy in Pateints With Exstrophy-Epispadias Complex: Are Higher Rates of Complications and Spontaneous Abortion Inevitable?

Urology 2021 Mar 1. Epub 2021 Mar 1.

Urology Department, Fundació Puigvert, Barcelona, Spain. Electronic address:

Objective: To report on the characteristics of pregnancy in female patients with EEC (exstrophy-epispadias complex), determining in particular whether they are at higher risk of spontaneous abortion or complications.

Materials And Method: Fifty patients diagnosed with EEC and treated in a reference center for this pathology were reviewed. Those with an incomplete medical history were excluded, leaving a total of 37 women with a median follow-up of 26 years (1-48 years). Read More

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Ultrasonographic technique to differentiate enhanced myometrial vascularity/arteriovenous malformation from retained products of conception.

J Ultrasound 2021 Mar 2. Epub 2021 Mar 2.

Department of Obstetrics, Gynecology and Women's Health, Spectrum Health Medical Group, Grand Rapids, MI, USA.

Purpose: To objective of this study is to discuss the ultrasonographic technique to diagnose uterine enhanced myometrial vascularity/arteriovenous malformation (EMV/AVM) and differentiate it from retained products of conception. The study also reviews the management and outcome of EMV/AVM.

Methods: We present a series of three women who developed EMV after early pregnancy loss and a control case of incomplete abortion, where colour Doppler ultrasound was used to distinguish retained products of conception from features of EMV. Read More

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Maternal and Perinatal Outcome of Maternal Obesity at RSCM in 2014-2019.

Obstet Gynecol Int 2021 9;2021:6039565. Epub 2021 Feb 9.

Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo National General Hospital Jakarta, Pangeran Diponegoro Street 71, Jakarta, Indonesia.

Obesity is a pandemic found in many countries. It is estimated that, in 2025, more than 21% of women in the world will suffer from obesity and its number keeps increasing yearly. Obesity in pregnancy is one of the important challenges in obstetric services given the prevalence and potential adverse effects on the mother and fetus. Read More

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February 2021

Two cases of angular pregnancy with incomplete abortion treated with hysteroscopy: a case report and review of literature.

BMC Surg 2021 Feb 9;21(1):76. Epub 2021 Feb 9.

Department of Gynecology, The Second Affiliated Hospital of Zhejiang University School of Medicine, No88, Jiefang Road, Shangcheng District, Hangzhou, 310002, Zhejiang, People's Republic of China.

Background: Angular pregnancy is characterized as implant medial to the uterotubal junction in lateral angular of uterine. It was a rare obstetric complication with severe complications like uterine rupture and retained placenta.

Case Presentation: We report a case of 2 incomplete aborted angular pregnancy that was diagnosed and treated with hysteroscopy. Read More

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February 2021

Telemedicine medical abortion at home under 12 weeks' gestation: a prospective observational cohort study during the COVID-19 pandemic.

BMJ Sex Reprod Health 2021 Feb 4. Epub 2021 Feb 4.

Queen's Medical Research Institute, University of Edinburgh MRC Centre for Reproductive Health, Edinburgh, UK.

Background: In response to the COVID-19 pandemic, legislation and guidance were introduced in Scotland permitting medical abortion at home by telemedicine for pregnancies at less than 12 weeks' gestation. Women had a telephone consultation with a clinician. Routine ultrasound was not performed. Read More

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February 2021

Pathogenesis of uteroplacental acute atherosis: An update on current research.

Shu Li Yan-Wei Hu

Am J Reprod Immunol 2021 06 19;85(6):e13397. Epub 2021 Feb 19.

Department of Clinical Laboratory, Guangzhou Women & Children Medical Center, Guangzhou Medical University, Guangzhou, China.

Uteroplacental acute atherosis is a type of arterial vascular disease that affects the placenta during pregnancy and predominates in the maternal spiral arteries in the decidua basalis layer of the pregnant uterus. This condition is characterized by fibrin-like necrosis of the blood vessel walls, the accumulation of macrophages containing fat (foam cells), and the infiltration of macrophages around blood vessels. Uteroplacental acute atherosis is rare in normal pregnancy but occurs more frequently in patients with pregnancy complications, including preeclampsia, spontaneous preterm labor, preterm prelabor rupture of membranes, mid-trimester spontaneous abortion, fetal death, and small-for-gestational age. Read More

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Early pregnancy loss.

JAAPA 2021 03;34(3):22-27

Toni Jackson is an assistant professor in the PA program at Wake Forest University School of Medicine in Winston-Salem, N.C. At the time this article was written, she was an assistant professor in the PA program at High Point (N.C.) University. Elyse Watkins is an associate professor in the PA program at the University of Lynchburg in Lynchburg, Va., and an assistant clinical professor in the PA program at Florida State University in Tallahassee, Fla. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Abstract: Previously called spontaneous abortion, early pregnancy loss (EPL) is the preferred term encompassing threatened abortion, incomplete abortion, complete abortion, and anembryonic pregnancy. EPL has many causes, including chromosomal abnormalities, immunologic and infectious causes, and underlying maternal risk factors. Because many patients present with first-trimester bleeding, clinicians must know the appropriate evaluation and management techniques. Read More

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Identifying the risk factors and incidence of Asherman Syndrome in women with post-abortion uterine curettage.

J Obstet Gynaecol Res 2021 Apr 18;47(4):1549-1555. Epub 2021 Jan 18.

Department of Obstetrics and Gynecology, Memorial Ankara Hospital, Ankara, Turkey.

Aim: To evaluate the risk factors and incidence of Asherman Syndrome in women with post-abortion uterine evacuation and curettage.

Methods: A total of 2546 patients who had surgical abortion (uterine evacuation and curettage) before the 20th gestational week with indications of missed abortion, anembryonic pregnancy, incomplete abortion, and elective curettage in a tertiary antenatal care center were recruited. The patients were called and surveyed for their symptoms; including infertility, oligo-amenorrhea and recurrent pregnancy loss, preterm birth and intrauterine growth retardation and abnormal placentation as criteria of Asherman Syndrome. Read More

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Emergency hysterectomy in a tertiary care hospital: indications, surgical outcomes and challenges: a 2-year retrospective descriptive cross-sectional study.

Pan Afr Med J 2020 1;37:106. Epub 2020 Oct 1.

Directorate of Obstetrics and Gynaecology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Introduction: emergency hysterectomy (EH) remains a life-saving procedure in cases of life-threatening obstetric hemorrhage and other gynaecological emergencies. We aim to determine the indications, surgical outcomes and challenges of EH in our tertiary centre.

Methods: an ethically approved retrospective descriptive cross-sectional study on all EHs performed at a tertiary hospital during the period of 1 January 2018 to 31 December 2019 was conducted. Read More

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January 2021

Prophylactic antibiotics for preventing genital tract infection in women undergoing surgical procedures for incomplete abortion: a systematic review and meta-analysis of randomised controlled trials.

BJOG 2021 Jul 12;128(8):1273-1281. Epub 2021 Jan 12.

Department of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.

Background: Findings about the effect of prophylactic antibiotics in preventing genital tract infection (GTI) associated with surgical procedures used for incomplete abortions are conflicting. Some reported a decrease in infection associated with the use of antibiotic prophylaxis, whereas others found no significant reduction in GTI.

Objective: To synthesise systematically the evidence on the effect of prophylactic antibiotics compared with placebo in women undergoing surgical procedures for incomplete abortion. Read More

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Cervical priming before surgical abortion up to 13 weeks' gestation: a systematic review and metaanalyses for the National Institute for Health and Care Excellence-new clinical guidelines for England.

Am J Obstet Gynecol MFM 2020 11 2;2(4):100220. Epub 2020 Sep 2.

Sexual and Reproductive Health Services, NHS Lothian and the University of Edinburgh, Edinburgh, United Kingdom.

Objective: This study aimed to determine the optimal cervical priming regimen before surgical abortion up to and including 13 weeks' gestation.

Data Sources: Embase, MEDLINE, and the Cochrane Library were searched for publications up to February 2020. Experts were consulted for any ongoing or missed trials. Read More

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November 2020

Intrauterine bony fragments - An unexpected finding in the hysterectomy specimen.

Autops Case Rep 2020 Sep 2;10(4):e2020182. Epub 2020 Sep 2.

Lokmanya Tilak Municipal Medical College and Lokmanya Tilak Municipal General Hospital (LTMGH), Pathology Department. Mumbai, Maharashtra, India.

Intrauterine bony fragments (IUBF) are an unusual finding in hysterectomy specimen received in a histopathology laboratory. Females harboring IUBF may present non-specific symptoms like vaginal bleeding, leukorrhea, chronic pelvic pain, and secondary infertility. Herein we report the case of a 35-year-old female who presented vaginal discharge and bleeding for two years, since when she had an abortion. Read More

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September 2020

Chemical Fingerprint Analysis and Ultra-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Study of the Protective Effect of Buxue Yimu Granule in Medical-Induced Incomplete Abortion Rats.

Front Pharmacol 2020 30;11:578217. Epub 2020 Nov 30.

School of Medicine, Chengdu University, Chengdu, China.

Medical abortion is a common method to terminate an early pregnancy and often causes serious complications such as abnormal uterine bleeding and endometritis. Buxue Yimu granule (BYG) is a well-known traditional Chinese medicine prescription composed of five kinds of drugs and is widely used in gynecology and obstetrics. The aim of the present study was to establish the quality standard of BYG and investigate its protective effect on incomplete abortion. Read More

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November 2020

Options for Teens with No Options: A Self-Managed Second Trimester Abortion.

J Pediatr Adolesc Gynecol 2021 Apr 23;34(2):226-227. Epub 2020 Nov 23.

Mount Sinai Adolescent Health Center, Department of Pediatrics, Kravis Children's Hospital, Mount Sinai Hospital, New York, New York.

Background: Several states have deemed abortions as nonessential services, effectively calling for a halt to abortion care during the COVID-19 pandemic. In response, women might elect for self-managed abortions by obtaining abortion medications online.

Case: A 15-year-old girl presented with abdominal cramping and vaginal discharge after taking misoprostol obtained from an online retailer for a self-managed abortion in her second trimester during the COVID-19 pandemic. Read More

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Safety and efficacy of manual vacuum suction compared with conventional dilatation and sharp curettage and electric vacuum aspiration in surgical treatment of miscarriage: a randomized controlled trial.

BMC Pregnancy Childbirth 2020 Nov 16;20(1):695. Epub 2020 Nov 16.

Department of Obstetrics and Gynecology, International University of Health and Welfare Hospital, 537- 3 Iguchi, 329-2763, Nasushiobara City, Tochigi, Japan.

Background: The World Health Organization does not recommend dilatation and sharp curettage (D&C) for the surgical treatment of miscarriage during the first trimester because this may cause Asherman's syndrome due to endometrial damage; therefore, suction remains the primary treatment option. While manual vacuum aspiration (MVA) has been widely used since the 1990s outside Japan, the use of an MVA device (Women's MVA system) was approved in Japan in October 2015. Here, we examined the efficacy of the MVA kit in women surgically treated for miscarriage. Read More

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November 2020

Surgical and Reproductive Outcomes after Hysteroscopic Removal of Retained Products of Conception: A Systematic Review and Meta-analysis.

J Minim Invasive Gynecol 2021 02 6;28(2):204-217. Epub 2020 Nov 6.

Department of Woman, Child and General and Specialized Surgery, Obstetrics and Gynecology Unit, University of Campania, Luigi Vanvitelli, Naples, Italy (Drs. Stefano Cianci, Antonio Schiattarella, Gaetano Riemma, Pasquale De Franciscis).

Objective: To evaluate the impact of hysteroscopy for retained products of conception (RPOC) removal on surgical and reproductive outcomes.

Data Sources: Electronic databases (MEDLINE, Scopus, ClinicalTrials.gov, SciELO, EMBASE, and the Cochrane Central Register of Controlled Trials at the Cochrane Library) were searched from inception to March 2020. Read More

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February 2021

Systematic review: fetal death reporting and risk in Zika-affected pregnancies.

Trop Med Int Health 2021 02 27;26(2):133-145. Epub 2020 Nov 27.

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.

Objectives: Zika virus is linked to several adverse pregnancy outcomes. We assessed whether Zika infection during pregnancy is associated with increased risk of foetal death (miscarriage, stillbirth, abortion) and whether there is incomplete reporting of such deaths.

Methods: We searched PubMed, Embase, CINAHL, Web of Science and LILACS for studies reporting Zika-affected completed pregnancies (ending in foetal death or live birth), excluding studies whose aim required live birth. Read More

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February 2021