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Turk J Obstet Gynecol 2022 Jun;19(2):111-117

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.

Objective: To analyse the outcome of patients with symptomatic arterio-venous malformation (AVM), formed following pregnancy and managed by uterine artery embolization (UAE).

Materials And Methods: This retrospective study was conducted after ethical approval and included 15 patients presenting with abnormal uterine bleeding following pregnancy, who were suspected to have an AVM which later was confirmed by angiography and managed with UAE. Presenting symptoms, post-UAE complications and subsequent fertility outcomes were noted. Read More

World Neurosurg 2022 Jun 26. Epub 2022 Jun 26.

Department of Neurosurgery, Cooper University Hospital, Camden, NJ, United States. Electronic address:

Background: Middle meningeal artery embolization (MMAE) is a novel approach for treatment of chronic subdural hematoma (cSDH). Studies comparing different procedural techniques for MMAE are lacking. It is unclear whether isolated use of coils results in suboptimal outcomes compared to when particle embolization is also performed. Read More

Stud Fam Plann 2022 Jun 29. Epub 2022 Jun 29.

Centre for Distributive, Labor, and Social Studies (CEDLAS-UNLP, Argentina), National Council of Scientific and Technical Research (CONICET, Argentina), CP(1900) La Plata, Buenos Aires, Argentina and Centre for Economic Research (CINVE, Uruguay), Montevideo, 11200, Uruguay.

The Latin American and Caribbean adolescent fertility rates are among the highest in the world: about 1.7 million children are born to teen mothers every year, and most of them are declared unintended pregnancies. The region also has the highest rate of unintended pregnancy of any world region, and nearly half of such pregnancies end in abortion. Read More

Cad Saude Publica 2022 27;38(6):e00109721. Epub 2022 Jun 27.

Universidad Nacional Autónoma de México, Ciudad de México, México.

The objective was to estimate the direct medical cost of pregnancy care attributable to the failure of Mexico's teenage pregnancy prevention policy. From the provider's perspective, this economic study estimated the mean cost of prenatal care, childbirth, puerperium, abortion and complications. To quantify the costs attributable to policy failure, three scenarios were constructed: (a) total number of pregnancies; (b) number of pregnancies above the target; (c) number of unwanted pregnancies. Read More

J Med Virol 2022 Jun 28. Epub 2022 Jun 28.

Microbiology Unit, Hospital of Legnano, ASST Ovest Milanese, Legnano (Milan), Italy.

Parvovirus B19 (B19V) infection in pregnancy is mostly asymptomatic, but can cause complications including abortion and foetal hydrops. Although its infection is ubiquitous, seroprevalence among pregnant women varies according to different geographical areas. Since seroprevalence data in Italy are limited, the prevalence of antibodies and DNA in pregnant women was evaluated retrospectively, correlating the clinical situation of mothers and newborns. Read More

J Korean Med Sci 2022 Jun 27;37(25):e200. Epub 2022 Jun 27.

Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Background: To assess the clinical efficacy of intravenous immunoglobulin G (IVIG) administration combined with low-dose aspirin in women with unexplained recurrent pregnancy loss (RPL).

Methods: We retrospectively analyzed the medical records of patients who had been diagnosed with unexplained RPL and treated with IVIG and low-dose aspirin between January 2000 and March 2020 at Asan Medical Center. We analyzed pregnancy outcomes and their association with the percentage of natural killer (NK) cells. Read More

Contraception 2022 Jun 24. Epub 2022 Jun 24.

Rush University Medical Center, Department of Obstetrics and Gynecology. 1653 W Congress Parkway, Suite 208 Kellogg Chicago, IL, US 60612.

Objective: Compare complication rates of second trimester induction for abortion or fetal demise for patients with and without prior cesarean delivery.

Study Design: Retrospective cohort study examining induction for abortion or fetal demise for pregnancies from 14w0d-23w6d gestation at two urban academic medical centers from 2009-2019. Exclusion criteria included preterm labor or cervical insufficiency, neonatal interventions, or if misoprostol was not the primary induction method. Read More

Pathogens 2022 Jun 8;11(6). Epub 2022 Jun 8.

Food Microbiology Unit, Istituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", 00178 Rome, Italy.

Listeriosis is currently the fifth most common foodborne disease in Europe. Most cases are sporadic; however, outbreaks have also been reported. Compared to other foodborne infections, listeriosis has a modest incidence but can cause life-threatening complications, especially in elderly or immunocompromised people and pregnant women. Read More

Medicina (Kaunas) 2022 Jun 7;58(6). Epub 2022 Jun 7.

Division of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.

Several reports indicate that women with von Willebrand disease (VWD) are at an increased risk of bleeding and other complications during pregnancy and childbirth. The aim of this study was to investigate the effect of VWD on the course of pregnancy, childbirth, and the postpartum period. This was a retrospective study that compared many variables between women with VWD ( = 26) and women without VWD ( = 297,111) who gave birth between 2002 and 2016 in Slovenia. Read More

Int J Mol Sci 2022 Jun 14;23(12). Epub 2022 Jun 14.

Department of Obstetrics and Perinatology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland.

Kisspeptins are the family of neuropeptide products of the gene that exert the biological action by binding with the G-protein coupled receptor 54 (GPR54), also known as the KISS-1 receptor. The kisspeptin level dramatically increases during pregnancy, and the placenta is supposed to be its primary source. The role of kisspeptin has already been widely studied in hypogonadotropic hypogonadism, fertility, puberty disorders, and insulin resistance-related conditions, including type 2 diabetes mellitus, polycystic ovary syndrome, and obesity. Read More

Front Endocrinol (Lausanne) 2022 6;13:878853. Epub 2022 Jun 6.

Department of Traditional Chinese Medicine Gynecology, Changhai Hospital, Shanghai, China.

Purpose: This work aimed to evaluate the adverse effect of polycystic ovary syndrome (PCOS) on pregnancy outcomes of singletons after vitrification in women with frozen-thawed embryo transfer (FET).

Methods: Patients with/without PCOS who underwent FET from January 2013 and December 2018 were included. Propensity score matching (PSM) was used to reduce the influence of bias. Read More

Otolaryngol Head Neck Surg 2022 Jun 21:1945998221107547. Epub 2022 Jun 21.

Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Objective: The utilization of image-guided navigation during endoscopic sinus surgery (ESS) has increased significantly since its introduction. However, the most common associated complications are still unknown. This study describes and analyzes adverse events related to image-guided ESS. Read More

BMC Pregnancy Childbirth 2022 Jun 20;22(1):501. Epub 2022 Jun 20.

NHC Key Lab. of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Fudan University, 400020, Shanghai, China.

Background: Reproductive tract infections can cause serious adverse outcomes for pregnant women such as spontaneous abortion and preterm birth. However, it is unclear whether maternal reproductive tract infection before pregnancy would also be related to any adverse pregnancy outcomes. This study aims to investigate the association of maternal preconception reproductive tract infections with subsequent adverse pregnancy outcomes. Read More

BMC Immunol 2022 Jun 20;23(1):32. Epub 2022 Jun 20.

University of Aberdeen, Scotland, UK.

Background: Impaired spermatozoa immunogenicity can result in pregnancy complications such as recurrent spontaneous abortion (RSA). Given that spermatozoa contact with microbiota, it is possible that inappropriate microbiota composition in the reproductive tract could result in the alteration of spermatozoa antigenicity. Probiotics, as a representative of microbiota, may therefore have a beneficial effect on this altered immunogenicity. Read More

Sante Publique 2022 ;33(5):675-683

Introduction: Brazilian legislation restricts the practice of abortion. In Brazil, abortion is a major public health problem due to the morbidity, mortality and hospitalization caused by the practice of unsafe abortions. Complications related to induced abortion and miscarriages are treated in “maternity wards”, where obstetric violence can be perpetrated. Read More

Biomed Res Int 2022 9;2022:5095282. Epub 2022 Jun 9.

Department of Anesthesiology, Maternal and Child Health Hospital of Hubei Province, China.

Background: Patients have widely accepted abortion as a remedy for contraceptive failure all over the world. Esketamine is a new anesthetic, sedative, and analgesic drug. Fentanyl is an opioid receptor agonist and a commonly used sedative. Read More

Front Immunol 2022 1;13:918550. Epub 2022 Jun 1.

Key Laboratory of Organ Regeneration & Transplantation of Ministry of Education, Department of Obstetrics and Gynecology, The First Hospital of Jilin University, Changchun, China.

Uterine natural killer (uNK) cells are an immune subset located in the uterus. uNK cells have distinct tissue-specific characteristics compared to their counterparts in peripheral blood and lymphoid organs. Based on their location and the pregnancy status of the host, uNK cells are classified as endometrial NK (eNK) cells or decidua NK (dNK) cells. Read More

Knee Surg Sports Traumatol Arthrosc 2022 Jun 18. Epub 2022 Jun 18.

Gelenkpunkt - Sports and Joint Surgery, FIFA Medical Centre of Excellence, Olympiastraße 39, 6020, Innsbruck, Austria.

Purpose: The purpose of this systematic review is to describe the complications and downsides of robotic systems in total knee arthroplasty (TKA).

Methods: A comprehensive search according to the PRISMA guidelines was performed across PubMed, MEDLINE, Cochrane Central Register of Controlled Trials, Scopus, and Google Scholar from inception until December 2021. All articles of any study design directly reporting on complications and downsides of the robotic system in TKA were considered for inclusion. Read More

J Crohns Colitis 2022 Jun 16. Epub 2022 Jun 16.

Clinical and Research Centre for Inflammatory Bowel Disease, ISCARE a.s., Charles University in Prague, Czech Republic.

Background And Aims: Evidence on the safety of newer biologics during pregnancy is limited. We aimed to assess the safety of ustekinumab and vedolizumab treatment during gestation on pregnancy and infant outcome. Furthermore, we evaluated the placental transfer of these agents. Read More

Lupus Sci Med 2022 06;9(1)

Rheumatology, Barbara Volcker Center for Women and Rheumatic Diseases, Hospital for Special Surgery, Weill Cornell Medicine, New York, New York, USA

Objectives: To describe the outcomes of pregnancies in antiphospholipid antibody (aPL)-positive patients since the inception of the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Registry.

Methods: We identified persistently aPL-positive patients recorded as 'pregnant' during prospective follow-up, and defined as a composite of: (1) Preterm live delivery (PTLD) at or before 37th week due to pre-eclampsia (PEC), eclampsia, small-for-gestational age (SGA) and/or placental insufficiency (PI); or (2) Otherwise unexplained fetal death after the 10th week of gestation. The primary objective was to describe the characteristics of patients with and without aPL-related composite outcomes based on their first observed pregnancies following registry recruitment. Read More

Clin Cosmet Investig Dent 2022 7;14:153-170. Epub 2022 Jun 7.

Mizan Dental Clinic, Department of Dental Medicine, Mizan Aman, Ethiopia.

Background: Periodontal disease is characterized by the inflammation of all tissues that surround and support the teeth, and it is the most common public health problem worldwide. It has many different contributing factors, such as poor oral hygiene, smoking, anemia, bacterial plaque, poor economic status, and nutritional deficiency. It also causes different feto-maternal complications like preeclampsia, gestational diabetes, preterm labor, low birth weight, and early abortion. Read More

Afr J Prim Health Care Fam Med 2022 May 31;14(1):e1-e9. Epub 2022 May 31.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, United States of America.

Background:  Tanzania is a country experiencing multiple sexual health challenges, but providers receive no formal training in sexual health.

Aim:  This study aimed to assess (1) what sexual health challenges are commonly seen in clinics in Tanzania, (2) which are raised by patients, (3) which are not addressed and (4) which topics to prioritise for a sexual health curriculum.

Setting:  Healthcare settings in Tanzania. Read More

J Obstet Gynaecol 2022 Jun 9:1-9. Epub 2022 Jun 9.

Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.

In this retrospective study, we analysed clinical and demographic data from the medical records of 31 pregnant women with coronavirus disease 2019 (COVID-19) who were treated at our hospital between April 2020 and April 2021. The most common symptom was a fever; ∼10% of patients were asymptomatic. One patient with rapidly worsening pneumonia needed a Caesarean Section at 30 weeks and was admitted for intensive care. Read More

Front Endocrinol (Lausanne) 2022 23;13:851213. Epub 2022 May 23.

State Key Laboratory of Reproductive Medicine, Clinical Center of Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Objective: To study the influence of the previous cesarean section on the pregnancy outcomes and perinatal outcomes in single embryo transfer (SET) cycles in an fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) setting compared to those with previous vaginal delivery (VD). In addition, the association between fertility outcomes and different cesarean scar defect (CSD) sizes was studied.

Method: This was a retrospective cohort study conducted in the Reproductive Center of the First Affiliated Hospital of Nanjing Medical University. Read More

Eur J Obstet Gynecol Reprod Biol 2022 Jul 30;274:182-190. Epub 2022 May 30.

Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center, Houston, TX, USA.

Objective: Determine the impact of indication for selective reduction (SR) on co-twin survival in monochorionic gestations undergoing radiofrequency ablation (RFA) or bipolar cord coagulation (BCC).

Methods: PubMed and Web of Science were systematically searched from inception of databases to April 2021. Frequency of indications was compared between post-intervention co-twin survival and demise groups undergoing SR. Read More

PLoS One 2022 3;17(6):e0267545. Epub 2022 Jun 3.

Department of Maternity and Reproductive Health Nursing, College of Medicine and Health Science, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

Background: Unintended pregnancy due to disuse of family planning is the main cause of abortion globally. Women with a history of abortion are at higher risk of developing another unintended pregnancy, which may lead to repeated abortions and life-threatening complications. The immediate post-abortion period before women leave health institutions is a crucial time to provide family planning services. Read More

Front Cell Infect Microbiol 2022 17;12:838405. Epub 2022 May 17.

Microbiology, Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

A deep comprehension of the vaginal ecosystem may hold promise for unraveling the pathophysiology of pregnancy and may provide novel biomarkers to identify subjects at risk of maternal-fetal complications. In this prospective study, we assessed the characteristics of the vaginal environment in a cohort of pregnant women throughout their different gestational ages and puerperium. Both the vaginal bacterial composition and the vaginal metabolic profiles were analyzed. Read More

Am J Bioeth 2022 Jun 2:1-13. Epub 2022 Jun 2.

University of Virginia.

The upcoming U.S. Supreme Court decision in has the potential to eliminate or severely restrict access to legal abortion care in the United States. Read More

Curr Opin Obstet Gynecol 2022 06;34(3):114-121

IVIRMA.

Purpose Of Review: To summarize recent findings related to the risk of miscarriage in women with elevated BMI undergoing IVF, and the mechanisms involved in said risk.

Recent Findings: Miscarriage rates are increased in overweight and obese women in both natural and assisted reproduction. Oocyte and embryo quality assessed according to classic morphological static parameters does not seem to be affected by excessive female body weight. Read More

Fertil Steril 2022 Jul 28;118(1):111-122. Epub 2022 May 28.

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom; Birmingham Women's and Children's Foundation Hospital Trust, Edgbaston, Birmingham, United Kingdom.

Objective: To investigate whether a significant association between vitamin D status and the risk of miscarriage or recurrent miscarriage (RM) exists.

Design: Systematic review and meta-analysis.

Setting: Not applicable. Read More