Neurology 2020 09 6;95(10):e1372-e1380. Epub 2020 Jul 6.
From the Division of Epilepsy and Neurophysiology (A.J.S., M.L.D., T.L. , P.L.P., M.H.L.), Department of Anesthesiology, Critical Care and Pain Medicine (A.A.-A., R.C.T.), Department of Neurology (K.L., T.L., M.J.R., P.L.P., M.H.L., R.C.T.), Department of Psychiatry and Radiology (M.J.R.), and Department of Cardiology, Division of Cardiovascular Critical Care (R.R.T.), Boston Children's Hospital, MA.
Objective: To examine EEG features of major pathophysiology in children undergoing extracorporeal membrane oxygenation (ECMO).
Methods: This was a single-center, retrospective study of 201 pediatric patients on ECMO, using the first 24 hours of continuous EEG (cEEG) monitoring, collating background activity and electrographic seizures (ES) with imaging, ECMO type, and outcome.
Results: Severely abnormal cEEG background occurred in 12% (25/201), and was associated with death (sensitivity 0. Read More